ZA200802763B - Compositions and methods for preparation of poorly water soluble drugs with increased stability - Google Patents

Compositions and methods for preparation of poorly water soluble drugs with increased stability

Info

Publication number
ZA200802763B
ZA200802763B ZA200802763A ZA200802763A ZA200802763B ZA 200802763 B ZA200802763 B ZA 200802763B ZA 200802763 A ZA200802763 A ZA 200802763A ZA 200802763 A ZA200802763 A ZA 200802763A ZA 200802763 B ZA200802763 B ZA 200802763B
Authority
ZA
South Africa
Prior art keywords
compositions
preparation
methods
water soluble
increased stability
Prior art date
Application number
ZA200802763A
Inventor
De Tapas
Neil P Desai
Yang Andrew
Yim Zachary
Soon-Shiong
M D Patrick
Original Assignee
Abraxis Bioscience Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abraxis Bioscience Llc filed Critical Abraxis Bioscience Llc
Publication of ZA200802763B publication Critical patent/ZA200802763B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38Albumins
    • A61K38/385Serum albumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
ZA200802763A 2005-08-31 2006-08-30 Compositions and methods for preparation of poorly water soluble drugs with increased stability ZA200802763B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71286505P 2005-08-31 2005-08-31

Publications (1)

Publication Number Publication Date
ZA200802763B true ZA200802763B (en) 2009-10-28

Family

ID=41449779

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200802763A ZA200802763B (en) 2005-08-31 2006-08-30 Compositions and methods for preparation of poorly water soluble drugs with increased stability

Country Status (3)

Country Link
NO (1) NO344525B1 (en)
UA (3) UA108840C2 (en)
ZA (1) ZA200802763B (en)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6096331A (en) * 1993-02-22 2000-08-01 Vivorx Pharmaceuticals, Inc. Methods and compositions useful for administration of chemotherapeutic agents
CA2362338A1 (en) * 1998-07-30 2000-02-10 Human Rt. Pharmaceutically acceptable composition comprising an aqueous solution of paclitaxel and albumin
SI21222A (en) * 2002-05-28 2003-12-31 Krka, Tovarna Zdravil, D.D., Novo Mesto Method for preparation of nanoparticles
EP3470084A1 (en) * 2002-12-09 2019-04-17 Abraxis BioScience, LLC Compositions and methods of delivery of pharmacological agents
US7674816B2 (en) * 2003-12-23 2010-03-09 Abraxis Bioscience, Llc Substituted melatonin derivatives, process for their preparation, and methods of use

Also Published As

Publication number Publication date
UA108840C2 (en) 2015-06-25
NO344525B1 (en) 2020-01-27
UA95921C2 (en) 2011-09-26
NO20190306A1 (en) 2008-05-13
UA96273C2 (en) 2011-10-25

Similar Documents

Publication Publication Date Title
IL272236A (en) Compositions and methods for preparation of poorly water soluble drugs with increased stability
IL286802A (en) Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
IL184735A0 (en) Pharmaceutical formulations and methods of use
ZA200707898B (en) Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
ZA200900345B (en) Preparation of pharmaceutical formulations
EP1933862A4 (en) Methods and compositions for oral administration of proteins
IL198397A0 (en) Anilinopiperazine derivatives and methods of use thereof
IL190885A0 (en) Immunogenic compositions and methods of use
EP2024272A4 (en) Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same
HK1117519A1 (en) Substituted benzimidazoles and methods of preparation
IL195491A (en) Pharmaceutical compositions of tmc278 and processes for their preparation
IL198513A0 (en) Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives
IL193211A (en) Indazole-heteroaryl derivatives and pharmaceutical compositions comprising them
IL196594A0 (en) Derivatives of 4-trimethylammonium-3-aminobutyrate and 4-trimethylphosphonium-3-aminobutyrate as cpt-inhibitors
EP2051721A4 (en) Preparation and pharmaceutical use of euterpe oleracea (acai) extract compositions
IL188278A0 (en) Water soluble analgesic formulations and methods for production
IL191922A0 (en) Pharmaceutical formulations of oxcarbazepine and methods for its preparation
IL186277A0 (en) Dnt-maleate and methods of preparation thereof
ZA200802763B (en) Compositions and methods for preparation of poorly water soluble drugs with increased stability
IL192552A0 (en) Dnt-succinate and methods of preparation thereof
GB2452142A8 (en) Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the sa
IL191861A0 (en) Improved jasmonate derivatives, pharmaceutical compositions and methods of use thereof
IL192553A0 (en) Dnt-fumarate and methods of preparation thereof
IL190726A0 (en) Dnt-benzenesulfonate and methods of preparation thereof
IL198994A0 (en) Use of incensole and incensole acetate for the preparation of pharmaceutical compositions