ZA200800848B - Cell-permeable peptide inhibitors of the JNK signal transduction pathway - Google Patents
Cell-permeable peptide inhibitors of the JNK signal transduction pathwayInfo
- Publication number
- ZA200800848B ZA200800848B ZA200800848A ZA200800848A ZA200800848B ZA 200800848 B ZA200800848 B ZA 200800848B ZA 200800848 A ZA200800848 A ZA 200800848A ZA 200800848 A ZA200800848 A ZA 200800848A ZA 200800848 B ZA200800848 B ZA 200800848B
- Authority
- ZA
- South Africa
- Prior art keywords
- cell
- signal transduction
- transduction pathway
- peptide inhibitors
- permeable peptide
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 230000019491 signal transduction Effects 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
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- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/10—Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2740/16322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
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- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Virology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Microbiology (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Vascular Medicine (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/EP2005/009782 WO2007031098A1 (en) | 2005-09-12 | 2005-09-12 | Cell-permeable peptide inhibitors of the jnk signal transduction pathway |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200800848B true ZA200800848B (en) | 2009-05-27 |
Family
ID=35686501
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200800848A ZA200800848B (en) | 2005-09-12 | 2006-09-12 | Cell-permeable peptide inhibitors of the JNK signal transduction pathway |
Country Status (25)
Country | Link |
---|---|
US (5) | US8748395B2 (xx) |
EP (3) | EP2418217B1 (xx) |
JP (3) | JP5386169B2 (xx) |
KR (1) | KR101305533B1 (xx) |
CN (1) | CN101263157B (xx) |
AU (1) | AU2006291541B2 (xx) |
BR (1) | BRPI0616824B8 (xx) |
CA (1) | CA2621337C (xx) |
CY (2) | CY1112924T1 (xx) |
DK (2) | DK2418217T3 (xx) |
EA (1) | EA014330B1 (xx) |
ES (2) | ES2567708T3 (xx) |
HK (3) | HK1118841A1 (xx) |
HR (2) | HRP20120598T1 (xx) |
HU (1) | HUE029132T2 (xx) |
IL (2) | IL189133A (xx) |
ME (2) | ME02426B (xx) |
NO (1) | NO342272B1 (xx) |
PL (2) | PL1928903T3 (xx) |
PT (1) | PT1928903E (xx) |
RS (2) | RS52379B (xx) |
SI (2) | SI1928903T1 (xx) |
UA (1) | UA98101C2 (xx) |
WO (2) | WO2007031098A1 (xx) |
ZA (1) | ZA200800848B (xx) |
Families Citing this family (50)
Publication number | Priority date | Publication date | Assignee | Title |
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US8183339B1 (en) | 1999-10-12 | 2012-05-22 | Xigen S.A. | Cell-permeable peptide inhibitors of the JNK signal transduction pathway |
US20040082509A1 (en) | 1999-10-12 | 2004-04-29 | Christophe Bonny | Cell-permeable peptide inhibitors of the JNK signal transduction pathway |
US8080517B2 (en) | 2005-09-12 | 2011-12-20 | Xigen Sa | Cell-permeable peptide inhibitors of the JNK signal transduction pathway |
WO2007031098A1 (en) | 2005-09-12 | 2007-03-22 | Xigen S.A. | Cell-permeable peptide inhibitors of the jnk signal transduction pathway |
US8063012B2 (en) | 2006-09-19 | 2011-11-22 | Phylogica Limited | Neuroprotective peptide inhibitors of AP-1 signaling and uses therefor |
US8822409B2 (en) | 2007-06-20 | 2014-09-02 | Phylogica Limited | Compositions and uses thereof for the treatment of acute respiratory distress syndrome (ARDS) and clinical disorders associated with therewith |
US11969501B2 (en) | 2008-04-21 | 2024-04-30 | Dompé Farmaceutici S.P.A. | Auris formulations for treating otic diseases and conditions |
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WO2009143864A1 (en) | 2008-05-30 | 2009-12-03 | Xigen S.A. | Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of chronic or non-chronic inflammatory digestive diseases |
WO2009143865A1 (en) * | 2008-05-30 | 2009-12-03 | Xigen S.A. | Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases |
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WO2010072228A1 (en) * | 2008-12-22 | 2010-07-01 | Xigen S.A. | Novel transporter constructs and transporter cargo conjugate molecules |
EP2415478A4 (en) | 2009-03-30 | 2013-01-16 | Santen Pharmaceutical Co Ltd | PROPHYLAXIS OR THERAPY AGENTS FOR KIDNEY DISEASES AND METHODS OF PREVENTING OR TREATING NURSE DISEASES, EACH OF THEM WITH A JNK (C-JUN-N-TERMINAL KINASE) -IMBING PEPTIDE, AND USE OF THE PEPTIDE |
US20120077753A1 (en) * | 2009-06-25 | 2012-03-29 | Laxman Gangwani | Jnk inhibitors for use in treating spinal muscular atrophy |
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AU2014301631A1 (en) * | 2013-06-26 | 2015-08-27 | Xigen Inflammation Ltd. | New use of cell-permeable peptide inhibitors of the JNK signal transduction pathway for the treatment of various diseases |
WO2014206426A1 (en) * | 2013-06-26 | 2014-12-31 | Xigen Inflammation Ltd. | New use for jnk inhibitor molecules for treatment of various diseases |
WO2014206427A1 (en) | 2013-06-26 | 2014-12-31 | Xigen Inflammation Ltd. | New use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases |
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2012
- 2012-01-05 JP JP2012000381A patent/JP5727393B2/ja active Active
- 2012-05-08 HK HK12104474.3A patent/HK1163712A1/zh unknown
- 2012-07-04 CY CY20121100593T patent/CY1112924T1/el unknown
- 2012-07-19 HR HRP20120598TT patent/HRP20120598T1/hr unknown
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2013
- 2013-12-31 US US14/144,938 patent/US9290538B2/en active Active
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2014
- 2014-10-23 JP JP2014216270A patent/JP2015034171A/ja not_active Withdrawn
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2015
- 2015-03-26 IL IL237984A patent/IL237984A0/en unknown
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2016
- 2016-02-16 US US15/045,058 patent/US20160264630A1/en not_active Abandoned
- 2016-04-11 CY CY20161100290T patent/CY1117351T1/el unknown
- 2016-04-12 HR HRP20160379TT patent/HRP20160379T1/hr unknown
- 2016-10-24 HK HK16112196.9A patent/HK1223948A1/zh unknown
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2017
- 2017-06-21 US US15/628,771 patent/US20170320917A1/en not_active Abandoned
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2019
- 2019-07-29 US US16/525,234 patent/US20200062805A1/en not_active Abandoned
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