ZA200704246B - Solid medicinal preparation improved in solubility and stability and process for producing the same - Google Patents
Solid medicinal preparation improved in solubility and stability and process for producing the sameInfo
- Publication number
- ZA200704246B ZA200704246B ZA200704246A ZA200704246A ZA200704246B ZA 200704246 B ZA200704246 B ZA 200704246B ZA 200704246 A ZA200704246 A ZA 200704246A ZA 200704246 A ZA200704246 A ZA 200704246A ZA 200704246 B ZA200704246 B ZA 200704246B
- Authority
- ZA
- South Africa
- Prior art keywords
- solubility
- stability
- producing
- same
- medicinal preparation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/225—Polycarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Emergency Medicine (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2004310254 | 2004-10-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200704246B true ZA200704246B (en) | 2009-09-30 |
Family
ID=38772175
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200704246A ZA200704246B (en) | 2004-10-25 | 2005-10-20 | Solid medicinal preparation improved in solubility and stability and process for producing the same |
Country Status (4)
Country | Link |
---|---|
JP (1) | JP4782695B2 (en) |
KR (1) | KR101129456B1 (en) |
CN (1) | CN101048180B (en) |
ZA (1) | ZA200704246B (en) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20130069484A (en) * | 2011-12-15 | 2013-06-26 | 주식회사 삼양바이오팜 | Solid dispersion comprising celecoxib and a preparation method thereof |
CN104415340A (en) * | 2013-08-23 | 2015-03-18 | 中国科学院大连化学物理研究所 | Solid drug preparation and preparing method thereof |
KR101631846B1 (en) * | 2014-07-08 | 2016-06-20 | 한국유나이티드제약 주식회사 | Solid preparations containing choline alfoscerate and preparing method thereof |
CN104523599A (en) * | 2014-12-20 | 2015-04-22 | 长沙佰顺生物科技有限公司 | Anacetrapib containing solid dispersion and preparation method thereof |
CN104666260B (en) * | 2015-02-03 | 2018-01-19 | 山东新时代药业有限公司 | A kind of Ezetimibe tablet |
CN104546774B (en) * | 2015-02-03 | 2017-08-25 | 山东新时代药业有限公司 | A kind of glimepiride tablet |
CN104666261B (en) * | 2015-02-03 | 2017-11-10 | 山东新时代药业有限公司 | A kind of tablet of everolimus |
CN104523632B (en) * | 2015-02-03 | 2017-09-29 | 山东新时代药业有限公司 | A kind of Azilsartan tablet |
CN104666262B (en) * | 2015-02-03 | 2017-09-15 | 山东新时代药业有限公司 | A kind of razaxaban piece |
CN104546775B (en) * | 2015-02-03 | 2017-08-25 | 山东新时代药业有限公司 | A kind of atorvastatin agent |
CN104586814B (en) * | 2015-02-04 | 2017-11-10 | 山东新时代药业有限公司 | A kind of Aprepitant capsule |
CN104688698B (en) * | 2015-02-04 | 2018-01-19 | 山东新时代药业有限公司 | A kind of Cefditoren pivoxil Cephalosporins tablet |
CN105030703B (en) * | 2015-06-23 | 2018-03-23 | 上海旭东海普药业有限公司 | A kind of razaxaban piece of anti-treatment embolism class diseases and preparation method thereof |
CN107998085A (en) * | 2017-11-29 | 2018-05-08 | 乐普制药科技有限公司 | A kind of tablet containing Atorvastatin calcium alkali solid dispersion and preparation method thereof |
WO2019135420A1 (en) * | 2018-01-03 | 2019-07-11 | 김배용 | Composite using porous material and polymer, and use thereof |
CN114456781B (en) * | 2020-10-21 | 2023-05-26 | 中国石油化工股份有限公司 | Method for preparing solid dosage form from viscous salt-resistant fluid loss additive solution, solid dosage form fluid loss additive and application |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57206612A (en) * | 1982-04-16 | 1982-12-18 | Bayer Ag | Collapsible absorptive compressed mold article of hard soluble medicine |
JPH0597672A (en) * | 1991-10-08 | 1993-04-20 | Terumo Corp | Amide derivative-containing solid preparation and its production |
JP4027535B2 (en) * | 1998-05-26 | 2007-12-26 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | Powder containing fat-soluble drug |
DE19945594A1 (en) * | 1999-09-23 | 2001-03-29 | Boehringer Ingelheim Pharma | Substituted piperazine derivatives, their preparation and their use as medicines |
CA2324800A1 (en) * | 1999-11-10 | 2001-05-10 | Mary Anne Hickman | Use of apo b secretion/mtp inhibitors |
JP2001316248A (en) * | 2000-02-28 | 2001-11-13 | Eisai Co Ltd | Method of producing oily medicine containing composition |
WO2002069932A1 (en) * | 2001-03-05 | 2002-09-12 | Nippon Shinyaku Co., Ltd. | Foaming compositions |
JP3662566B2 (en) | 2002-02-28 | 2005-06-22 | 日本たばこ産業株式会社 | Ester compound and its pharmaceutical use |
SG165154A1 (en) * | 2002-02-28 | 2010-10-28 | Japan Tobacco Inc | Ester compound and medical use thereof |
US20050181049A1 (en) * | 2003-11-19 | 2005-08-18 | Dong Liang C. | Composition and method for enhancing bioavailability |
-
2005
- 2005-10-20 JP JP2006543229A patent/JP4782695B2/en not_active Expired - Fee Related
- 2005-10-20 CN CN2005800364952A patent/CN101048180B/en not_active Expired - Fee Related
- 2005-10-20 KR KR1020107024005A patent/KR101129456B1/en not_active IP Right Cessation
- 2005-10-20 ZA ZA200704246A patent/ZA200704246B/en unknown
Also Published As
Publication number | Publication date |
---|---|
JP4782695B2 (en) | 2011-09-28 |
KR20100120244A (en) | 2010-11-12 |
CN101048180A (en) | 2007-10-03 |
KR101129456B1 (en) | 2012-03-28 |
JPWO2006046623A1 (en) | 2008-05-22 |
CN101048180B (en) | 2011-06-29 |
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