ZA200700537B - Benzyloxy derivatives at MAOB inhibitors - Google Patents
Benzyloxy derivatives at MAOB inhibitorsInfo
- Publication number
- ZA200700537B ZA200700537B ZA200700537A ZA200700537A ZA200700537B ZA 200700537 B ZA200700537 B ZA 200700537B ZA 200700537 A ZA200700537 A ZA 200700537A ZA 200700537 A ZA200700537 A ZA 200700537A ZA 200700537 B ZA200700537 B ZA 200700537B
- Authority
- ZA
- South Africa
- Prior art keywords
- maob inhibitors
- benzyloxy derivatives
- benzyloxy
- derivatives
- maob
- Prior art date
Links
- 102100028116 Amine oxidase [flavin-containing] B Human genes 0.000 title 1
- 101000768078 Homo sapiens Amine oxidase [flavin-containing] B Proteins 0.000 title 1
- 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
- C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04103710 | 2004-08-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200700537B true ZA200700537B (en) | 2008-05-28 |
Family
ID=35456889
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200700537A ZA200700537B (en) | 2004-08-02 | 2007-01-18 | Benzyloxy derivatives at MAOB inhibitors |
Country Status (17)
Country | Link |
---|---|
US (1) | US7456210B2 (ru) |
EP (1) | EP1776337A2 (ru) |
JP (1) | JP4629105B2 (ru) |
CN (1) | CN100560566C (ru) |
AR (1) | AR050193A1 (ru) |
AU (1) | AU2005268894B2 (ru) |
BR (1) | BRPI0514077A (ru) |
CA (1) | CA2575018A1 (ru) |
HK (1) | HK1108432A1 (ru) |
IL (1) | IL180791A0 (ru) |
MX (1) | MX2007001169A (ru) |
NO (1) | NO20070972L (ru) |
NZ (1) | NZ552649A (ru) |
RU (1) | RU2378270C2 (ru) |
TW (1) | TWI291349B (ru) |
WO (1) | WO2006013049A2 (ru) |
ZA (1) | ZA200700537B (ru) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7501528B2 (en) * | 2005-03-15 | 2009-03-10 | Hoffmann-La Roche Inc. | Method for preparing enantiomerically pure 4-pyrrolidino phenylbenzyl ether derivatives |
KR101220182B1 (ko) * | 2009-02-25 | 2013-01-11 | 에스케이바이오팜 주식회사 | 치환된 아졸 유도체 화합물, 이를 포함하는 약제학적 조성물 및 이를 이용한 파킨슨씨 병 치료방법 |
US9624170B2 (en) * | 2013-12-26 | 2017-04-18 | Takeda Pharmaceutical Company Limited | 4-(piperrazin-1-yl)-pyrrolidin-2-one compounds as monoacylglycerol lipase (MAGL) inhibitors |
EP3762364B1 (en) | 2018-03-08 | 2023-08-23 | Sunshine Lake Pharma Co., Ltd. | Pyrrolidineamide derivatives and uses thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2500450A1 (fr) * | 1981-02-25 | 1982-08-27 | Delalande Sa | Nouveaux derives aminomethyl-5 oxazolidiniques, leur procede de preparation et leur application en therapeutique |
US5679715A (en) | 1995-06-07 | 1997-10-21 | Harris; Richard Y. | Method for treating multiple sclerosis |
EP0906090A1 (en) | 1996-03-15 | 1999-04-07 | Somerset Pharmaceuticals, Inc. | Method for preventing and treating peripheral neurophathy by administering selegiline |
WO2001034172A2 (en) | 1999-11-05 | 2001-05-17 | Vela Pharmaceuticals Inc. | Methods and compositions for treating reward deficiency syndrome |
PE20050077A1 (es) | 2002-09-20 | 2005-03-01 | Hoffmann La Roche | Derivados de 4-pirrolidino-fenil-bencil-eter |
-
2005
- 2005-07-27 RU RU2007103236/04A patent/RU2378270C2/ru not_active IP Right Cessation
- 2005-07-27 US US11/190,626 patent/US7456210B2/en not_active Expired - Fee Related
- 2005-07-27 MX MX2007001169A patent/MX2007001169A/es active IP Right Grant
- 2005-07-27 BR BRPI0514077-3A patent/BRPI0514077A/pt not_active IP Right Cessation
- 2005-07-27 JP JP2007524232A patent/JP4629105B2/ja not_active Expired - Fee Related
- 2005-07-27 CN CNB2005800258332A patent/CN100560566C/zh not_active Expired - Fee Related
- 2005-07-27 WO PCT/EP2005/008143 patent/WO2006013049A2/en active Application Filing
- 2005-07-27 NZ NZ552649A patent/NZ552649A/en not_active IP Right Cessation
- 2005-07-27 EP EP05764454A patent/EP1776337A2/en not_active Withdrawn
- 2005-07-27 CA CA002575018A patent/CA2575018A1/en not_active Abandoned
- 2005-07-27 AU AU2005268894A patent/AU2005268894B2/en not_active Expired - Fee Related
- 2005-07-29 TW TW094125837A patent/TWI291349B/zh not_active IP Right Cessation
- 2005-08-01 AR ARP050103193A patent/AR050193A1/es not_active Application Discontinuation
-
2007
- 2007-01-18 IL IL180791A patent/IL180791A0/en unknown
- 2007-01-18 ZA ZA200700537A patent/ZA200700537B/xx unknown
- 2007-02-21 NO NO20070972A patent/NO20070972L/no not_active Application Discontinuation
- 2007-12-18 HK HK07113762.2A patent/HK1108432A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
AU2005268894A1 (en) | 2006-02-09 |
IL180791A0 (en) | 2007-06-03 |
NZ552649A (en) | 2010-05-28 |
RU2378270C2 (ru) | 2010-01-10 |
CN1993319A (zh) | 2007-07-04 |
BRPI0514077A (pt) | 2008-05-27 |
AU2005268894B2 (en) | 2010-12-16 |
AR050193A1 (es) | 2006-10-04 |
US7456210B2 (en) | 2008-11-25 |
NO20070972L (no) | 2007-02-28 |
TW200612912A (en) | 2006-05-01 |
WO2006013049A3 (en) | 2006-06-22 |
CA2575018A1 (en) | 2006-02-09 |
MX2007001169A (es) | 2007-03-12 |
US20060025599A1 (en) | 2006-02-02 |
WO2006013049A2 (en) | 2006-02-09 |
RU2007103236A (ru) | 2008-09-10 |
EP1776337A2 (en) | 2007-04-25 |
JP2008508335A (ja) | 2008-03-21 |
CN100560566C (zh) | 2009-11-18 |
HK1108432A1 (en) | 2008-05-09 |
JP4629105B2 (ja) | 2011-02-09 |
TWI291349B (en) | 2007-12-21 |
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