ZA200306885B - Novel expression vectors - Google Patents

Novel expression vectors

Info

Publication number
ZA200306885B
ZA200306885B ZA200306885A ZA200306885A ZA200306885B ZA 200306885 B ZA200306885 B ZA 200306885B ZA 200306885 A ZA200306885 A ZA 200306885A ZA 200306885 A ZA200306885 A ZA 200306885A ZA 200306885 B ZA200306885 B ZA 200306885B
Authority
ZA
South Africa
Prior art keywords
vectors
present
expression vectors
provides
expression
Prior art date
Application number
ZA200306885A
Other languages
English (en)
Inventor
Daly John
Original Assignee
Gene Stream Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gene Stream Pty Ltd filed Critical Gene Stream Pty Ltd
Publication of ZA200306885B publication Critical patent/ZA200306885B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H6/00—Angiosperms, i.e. flowering plants, characterised by their botanic taxonomy
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Environmental Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physiology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Animal Husbandry (AREA)
  • Botany (AREA)
  • Developmental Biology & Embryology (AREA)
  • Analytical Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Compositions Of Oxide Ceramics (AREA)
  • Image Generation (AREA)
ZA200306885A 2001-03-09 2003-09-03 Novel expression vectors ZA200306885B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27477001P 2001-03-09 2001-03-09

Publications (1)

Publication Number Publication Date
ZA200306885B true ZA200306885B (en) 2009-03-25

Family

ID=23049549

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200306885A ZA200306885B (en) 2001-03-09 2003-09-03 Novel expression vectors

Country Status (13)

Country Link
US (3) US7157272B2 (xx)
EP (1) EP1373528B1 (xx)
JP (2) JP2004530425A (xx)
KR (1) KR100917939B1 (xx)
CN (1) CN100471956C (xx)
AT (1) ATE404679T1 (xx)
AU (1) AU2002242474B2 (xx)
CA (1) CA2440148C (xx)
DE (2) DE02708018T1 (xx)
IL (2) IL157756A0 (xx)
NZ (1) NZ528000A (xx)
WO (1) WO2002072844A1 (xx)
ZA (1) ZA200306885B (xx)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7598079B2 (en) 1998-12-24 2009-10-06 Novation Pharmaceuticals, Inc. Assay for identifying compounds which affect stability of mRNA
CA2440148C (en) * 2001-03-09 2012-07-10 Gene Stream Pty Ltd Novel expression vectors
CA2830887C (en) 2001-06-05 2016-11-29 Curevac Gmbh Pharmaceutical composition containing a stabilised mrna optimised for translation in its coding regions
WO2004025264A2 (en) * 2002-09-16 2004-03-25 Promega Corporation Rapidly degraded reporter fusion proteins
DE102004042546A1 (de) * 2004-09-02 2006-03-09 Curevac Gmbh Kombinationstherapie zur Immunstimulation
AR053279A1 (es) * 2005-05-19 2007-04-25 Monsanto Technology Llc Regulacion post-transcripcional de la expresion genica
US20070212332A1 (en) * 2005-08-11 2007-09-13 Department Of Veterans Affairs Methods for accelerating bone repair
EP1760092A1 (en) * 2005-08-26 2007-03-07 Applied Research Systems ARS Holding N.V. System for screening cells for high expression of a protein of interest
DE102005046490A1 (de) * 2005-09-28 2007-03-29 Johannes-Gutenberg-Universität Mainz Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen
WO2007038757A2 (en) * 2005-09-28 2007-04-05 Attagene Inc. Methods and compositions for non-invasive assessment of gene expression
US20070245258A1 (en) * 2006-04-13 2007-10-18 Codman Neuro Sciences Sàrl Graphical user interface of an external control device for controlling an implantable medical device while minimizing human error
WO2008074025A2 (en) * 2006-12-13 2008-06-19 Idiverse, Inc. Novel genes and rna molecules that confer stress tolerance
US20080189804A1 (en) * 2006-12-13 2008-08-07 Dickman Martin B Novel genes and rna molecules that confer stress tolerance
WO2008074100A1 (en) * 2006-12-21 2008-06-26 Gene Stream Pty Ltd Bioluminescent assays utilising secreted luciferases
EP2176423A1 (en) * 2007-07-11 2010-04-21 Koninklijke Philips Electronics N.V. In vivo expression analysis using ultrasound-induced transfection of reporter constructs
US20110071047A1 (en) * 2007-10-27 2011-03-24 O.D. 260 Inc. Promoter detection and analysis
US20090111099A1 (en) * 2007-10-27 2009-04-30 Yongsheng Ma Promoter Detection and Analysis
KR101204895B1 (ko) 2010-01-27 2012-11-26 단국대학교 산학협력단 Ｐｒｃ１ 유전자 프로모터의 삭제변이 프로모터를 함유하는 암세포 특이적 발현벡터
US8822663B2 (en) 2010-08-06 2014-09-02 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
CA3162352A1 (en) 2010-10-01 2012-04-05 Modernatx, Inc. Modified nucleosides, nucleotides, and nucleic acids, and uses thereof
CN108265038A (zh) 2010-12-03 2018-07-10 基因流股份有限公司 改善的光-发射分子
AU2012236099A1 (en) 2011-03-31 2013-10-03 Moderna Therapeutics, Inc. Delivery and formulation of engineered nucleic acids
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
US9428535B2 (en) 2011-10-03 2016-08-30 Moderna Therapeutics, Inc. Modified nucleosides, nucleotides, and nucleic acids, and uses thereof
EP2791160B1 (en) 2011-12-16 2022-03-02 ModernaTX, Inc. Modified mrna compositions
US9572897B2 (en) 2012-04-02 2017-02-21 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
US9303079B2 (en) 2012-04-02 2016-04-05 Moderna Therapeutics, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
AU2013243946A1 (en) 2012-04-02 2014-10-30 Moderna Therapeutics, Inc. Modified polynucleotides for the production of membrane proteins
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
LT2922554T (lt) 2012-11-26 2022-06-27 Modernatx, Inc. Terminaliai modifikuota rnr
US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
CN104099357B (zh) * 2013-04-12 2016-09-21 中国科学院上海生命科学研究院 检测蛋白质稳定性的方法及其应用
US10023626B2 (en) 2013-09-30 2018-07-17 Modernatx, Inc. Polynucleotides encoding immune modulating polypeptides
CA2926218A1 (en) 2013-10-03 2015-04-09 Moderna Therapeutics, Inc. Polynucleotides encoding low density lipoprotein receptor
EP3452101A2 (en) * 2016-05-04 2019-03-13 CureVac AG Rna encoding a therapeutic protein
MX2018015540A (es) 2016-06-20 2019-04-11 Janssen Vaccines & Prevention Bv Promotor bidireccional potente y equilibrado.
WO2018045177A1 (en) * 2016-09-01 2018-03-08 Chimera Bioengineering, Inc. Gold optimized car t-cells
JP2021518747A (ja) * 2018-02-13 2021-08-05 キメラ・バイオエンジニアリング，インコーポレーテッド Ｒｎａ不安定化エレメントを使用した遺伝子発現の調整
EP4067495A4 (en) * 2019-11-26 2023-06-14 Korea Research Institute of Bioscience and Biotechnology CONSTRUCTION OF mRNA FOR PROTEIN EXPRESSION AND ASSOCIATED USE
WO2022204471A1 (en) * 2021-03-26 2022-09-29 Ptc Therapeutics Inc. Regulation of transgene expression using a small molecule inducible splicing switch
KR20220159909A (ko) * 2021-05-25 2022-12-05 한국생명공학연구원 단백질 발현용 mRNA 제조방법 및 이에 의해 제조된 mRNA의 용도

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE283279T1 (de) * 1993-05-18 2004-12-15 Macfarlane Burnet Ct For Medic Therapeutische inhaltsstoffe
US5464758A (en) 1993-06-14 1995-11-07 Gossen; Manfred Tight control of gene expression in eucaryotic cells by tetracycline-responsive promoters
US5587300A (en) * 1994-04-26 1996-12-24 Wisconsin Ulumni Research Foundation Method to increase regulatory molecule production
US5650135A (en) 1994-07-01 1997-07-22 The Board Of Trustees Of The Leland Stanford Junior University Non-invasive localization of a light-emitting conjugate in a mammal
US5777079A (en) 1994-11-10 1998-07-07 The Regents Of The University Of California Modified green fluorescent proteins
US5625048A (en) 1994-11-10 1997-04-29 The Regents Of The University Of California Modified green fluorescent proteins
US5804387A (en) 1996-02-01 1998-09-08 The Board Of Trustees Of The Leland Stanford Junior University FACS-optimized mutants of the green fluorescent protein (GFP)
DE69738737D1 (de) * 1996-12-16 2008-07-10 Eisai R&D Man Co Ltd Verfahren zur herstellung von retroviralen vektoren für die gentherapie
US6231880B1 (en) * 1997-05-30 2001-05-15 Susan P. Perrine Compositions and administration of compositions for the treatment of blood disorders
US20030083272A1 (en) * 1997-09-19 2003-05-01 Lahive & Cockfield, Llp Sense mrna therapy
US6130313A (en) * 1997-10-02 2000-10-10 Clontech Laboratories, Inc. Rapidly degrading GFP-fusion proteins
US6306600B1 (en) * 1998-04-17 2001-10-23 Clontech Laboratories, Inc. Rapidly degrading GFP-fusion proteins and methods of use
US5965421A (en) * 1997-11-26 1999-10-12 Human Genome Sciences, Inc. Human IRAK-2
JPH11266872A (ja) * 1998-03-20 1999-10-05 Suntory Ltd ＮＦ−κＢの活性化を抑制する物質のスクリーニング方法
US20040002056A1 (en) * 1998-05-12 2004-01-01 Lorens James B. Methods of screening for bioactive agents using cells transformed with self-inactivating viral vectors
US6307123B1 (en) * 1998-05-18 2001-10-23 Dekalb Genetics Corporation Methods and compositions for transgene identification
GB9828709D0 (en) * 1998-12-24 1999-02-17 Novartis Ag Assay
US6635671B1 (en) * 1998-12-24 2003-10-21 Novation Pharmaceuticals Inc. Compounds which affect mRNA stability and uses therefor
US20020102638A1 (en) * 2000-01-31 2002-08-01 Rosen Craig A. Nucleic acids, proteins, and antibodies
US6841362B1 (en) * 2000-02-29 2005-01-11 The Trustees Of Columbia University In The City Of New York Melanoma differentiation associated gene-7 promoter and uses thereof
AU2001257428A1 (en) * 2000-04-28 2001-11-12 Message Pharmaceuticals, Inc. Methods for identifying novel nucleic acid regulatory elements and compounds that affect the regulation
CA2440148C (en) * 2001-03-09 2012-07-10 Gene Stream Pty Ltd Novel expression vectors
WO2012143020A1 (en) * 2011-04-20 2012-10-26 King Faisal Specialist Hospital And Research Centre Multiple interferon and virus response element cell-based fluorescence system
US20180305776A1 (en) * 2017-04-20 2018-10-25 The Board Of Trustees Of The Leland Stanford Junior University Myc-reporters, cells containing myc-reporters and methods of use thereof

Also Published As

Publication number Publication date
CN1503844A (zh) 2004-06-09
EP1373528B1 (en) 2008-08-13
EP1373528A4 (en) 2004-12-29
AU2002242474B2 (en) 2004-05-20
DE02708018T1 (de) 2004-09-30
CA2440148C (en) 2012-07-10
US20040115704A1 (en) 2004-06-17
EP1373528A1 (en) 2004-01-02
KR100917939B1 (ko) 2009-09-21
CA2440148A1 (en) 2002-09-19
US9994858B2 (en) 2018-06-12
JP2011015685A (ja) 2011-01-27
IL157756A (en) 2010-12-30
US20070298417A1 (en) 2007-12-27
US20040209274A2 (en) 2004-10-21
JP2004530425A (ja) 2004-10-07
ATE404679T1 (de) 2008-08-15
KR20030092013A (ko) 2003-12-03
US7157272B2 (en) 2007-01-02
IL157756A0 (en) 2004-03-28
NZ528000A (en) 2005-09-30
WO2002072844A1 (en) 2002-09-19
DE60228212D1 (de) 2008-09-25
US20180305705A1 (en) 2018-10-25
CN100471956C (zh) 2009-03-25

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