ZA200303223B - Novel polymorphic forms of 5-[4-[N-methyl-N-(2-pyridyl)amino]ethoxy]benzyl] thiazolidine-2,4-dione maleate and process for their preparation. - Google Patents

Novel polymorphic forms of 5-[4-[N-methyl-N-(2-pyridyl)amino]ethoxy]benzyl] thiazolidine-2,4-dione maleate and process for their preparation.

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Publication number
ZA200303223B
ZA200303223B ZA200303223A ZA200303223A ZA200303223B ZA 200303223 B ZA200303223 B ZA 200303223B ZA 200303223 A ZA200303223 A ZA 200303223A ZA 200303223 A ZA200303223 A ZA 200303223A ZA 200303223 B ZA200303223 B ZA 200303223B
Authority
ZA
South Africa
Prior art keywords
thiazolidine
pyridyl
ethoxy
benzyl
amino
Prior art date
Application number
ZA200303223A
Inventor
Prabhakar Chebiyyam
Vyas Krishnamurthi
Om Reddy Gaddam
Ramabhadra Sarma Mamillapalli
Vishnuvardhann Reddy Seella
Original Assignee
Reddys Lab Ltd Dr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reddys Lab Ltd Dr filed Critical Reddys Lab Ltd Dr
Publication of ZA200303223B publication Critical patent/ZA200303223B/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA200303223A 2000-09-26 2003-04-24 Novel polymorphic forms of 5-[4-[N-methyl-N-(2-pyridyl)amino]ethoxy]benzyl] thiazolidine-2,4-dione maleate and process for their preparation. ZA200303223B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN805CH2000 2000-09-26

Publications (1)

Publication Number Publication Date
ZA200303223B true ZA200303223B (en) 2004-07-26

Family

ID=29266775

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200303223A ZA200303223B (en) 2000-09-26 2003-04-24 Novel polymorphic forms of 5-[4-[N-methyl-N-(2-pyridyl)amino]ethoxy]benzyl] thiazolidine-2,4-dione maleate and process for their preparation.

Country Status (15)

Country Link
EP (1) EP1322647A1 (en)
JP (1) JP2004509961A (en)
AU (1) AU9123201A (en)
BR (1) BR0114196A (en)
CA (1) CA2426117A1 (en)
CZ (1) CZ2003864A3 (en)
HU (1) HUP0301161A3 (en)
IL (1) IL155036A0 (en)
MX (1) MXPA03002580A (en)
NO (1) NO324968B1 (en)
NZ (1) NZ525498A (en)
PL (1) PL360661A1 (en)
SK (1) SK3752003A3 (en)
WO (1) WO2002026737A1 (en)
ZA (1) ZA200303223B (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020137940A1 (en) 1997-12-16 2002-09-26 Smithkline Beecham P.L.C. 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2, 4-dione, maleic acid salt, hydrate as pharmaceutical
US6664278B2 (en) 1997-12-16 2003-12-16 Smithkline Beecham P.L.C. Hydrate of 5-[4-[2-(N-methyl-N-(2-pyridil)amino)ethoxy]benzyl]thiazolidine-2,4-dione maleic acid salt
GB9726563D0 (en) 1997-12-16 1998-02-11 Smithkline Beecham Plc Novel pharmaceutical
PE20010044A1 (en) 1999-04-23 2001-03-10 Smithkline Beecham Plc SALT POLYMORPH OF MALEIC ACID OF 5- [4- [2- (N-METHYL-N- (2-PYRIDYL) AMINO) ETHOXY] BENZYL] -THAZOLIDINE-2,4-DIONA
HUP0200929A3 (en) 1999-04-23 2004-03-29 Smithkline Beecham Plc Thiazolidinedione derivative and its use as antidiabetic and process for preparation thereof
US20040248945A1 (en) 1999-04-23 2004-12-09 Smithkline Beecham P.L.C. Thiazolidinedione derivative and its use as antidiabetic
WO2004062667A1 (en) * 2003-01-08 2004-07-29 Dr. Reddy's Laboratories Limited Amorphous form of rosiglitazone maleate and process for preparation thereof
GB0307259D0 (en) * 2003-03-28 2003-05-07 Glaxo Group Ltd Process
EP1468997A3 (en) * 2003-04-18 2004-11-03 CHEMI S.p.A. Polymorphous forms of rosiglitazone maleate
GB2405403A (en) * 2003-08-29 2005-03-02 Cipla Ltd Rosiglitazone maleate of particular polymorphic forms and methods of preparing rosiglitazone free base
UA83504C2 (en) 2003-09-04 2008-07-25 Селджин Корпорейшн Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione
AR047541A1 (en) * 2004-02-13 2006-01-25 Sandoz Ag PHOSPHATE OF 5 - [[4- [2-METHYL-2-PYRIDINYL-AMINO-ETOXI] PHENYL] METHYL] -2,4 THYZOLIDINADION (ROSIGLITAZONE) AND ITS POLYMORPHIC FORMS
EP1753759A2 (en) * 2004-03-31 2007-02-21 Sandoz AG Novel co-precipitate of amorphous rosiglitazone
JP2005350451A (en) * 2004-05-11 2005-12-22 Santen Pharmaceut Co Ltd Agent for treating keratoconjunctival trouble
CA2566098A1 (en) * 2004-05-11 2005-11-17 Santen Pharmaceutical Co., Ltd. Therapeutic agent for keratoconjunctival disorder
CZ2004844A3 (en) * 2004-07-27 2006-03-15 Zentiva, A. S Salt of oxalic acid with 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione, process for its preparation and its use
ITMI20041537A1 (en) * 2004-07-28 2004-10-28 Chemi Spa NEW POLYMORPHIC SHAPE OF EVIL ROSIGLITAZONE
CZ298424B6 (en) * 2005-05-24 2007-09-26 Zentiva, A. S. Crystallization process of rosiglitazone and derivatives thereof from mixed solutions
EP2184055A1 (en) 2008-11-07 2010-05-12 LEK Pharmaceuticals d.d. Process for preparing solid dosage forms of rosiglitazone maleate

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0842925A1 (en) * 1987-09-04 1998-05-20 Beecham Group Plc Substituted thiazolidinedione derivatives
GB9218830D0 (en) * 1992-09-05 1992-10-21 Smithkline Beecham Plc Novel compounds
EP0844997A1 (en) * 1996-06-19 1998-06-03 Dr. Reddy's Research Foundation Novel polymorphic forms of troglitazone having enhanced anti-diabetic activity and a process for their preparation
CN1221417A (en) * 1996-07-26 1999-06-30 雷迪博士研究基金会 Thiazolidinedione compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions thereof
GB9726566D0 (en) * 1997-12-16 1998-02-11 Smithkline Beecham Plc Novel pharmaceutical
HUP0200929A3 (en) * 1999-04-23 2004-03-29 Smithkline Beecham Plc Thiazolidinedione derivative and its use as antidiabetic and process for preparation thereof
PE20010044A1 (en) * 1999-04-23 2001-03-10 Smithkline Beecham Plc SALT POLYMORPH OF MALEIC ACID OF 5- [4- [2- (N-METHYL-N- (2-PYRIDYL) AMINO) ETHOXY] BENZYL] -THAZOLIDINE-2,4-DIONA

Also Published As

Publication number Publication date
NO20031356L (en) 2003-05-26
WO2002026737A8 (en) 2003-11-06
CZ2003864A3 (en) 2004-01-14
IL155036A0 (en) 2003-10-31
MXPA03002580A (en) 2003-10-15
HUP0301161A3 (en) 2005-04-28
NZ525498A (en) 2004-11-26
PL360661A1 (en) 2004-09-20
CA2426117A1 (en) 2002-04-04
BR0114196A (en) 2003-07-22
SK3752003A3 (en) 2005-03-04
JP2004509961A (en) 2004-04-02
HUP0301161A2 (en) 2003-11-28
AU9123201A (en) 2002-04-08
NO20031356D0 (en) 2003-03-25
WO2002026737A1 (en) 2002-04-04
EP1322647A1 (en) 2003-07-02
NO324968B1 (en) 2008-01-14

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