YU49995A - Polinukleotidna vakcina za virus herpesa - Google Patents
Polinukleotidna vakcina za virus herpesaInfo
- Publication number
- YU49995A YU49995A YU49995A YU49995A YU49995A YU 49995 A YU49995 A YU 49995A YU 49995 A YU49995 A YU 49995A YU 49995 A YU49995 A YU 49995A YU 49995 A YU49995 A YU 49995A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- hsv
- pnv
- immunization
- animals
- herpes virus
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
POLINUKLEOTIDNA VAKCINA ZA VIRUS HERPESA - Geni koji kodiraju proteine herpes simpleks virusa tipa 2 (HSV-2) se kloniraju u eukariotične ekspresione vaktore da bi ekspresionisali kodirane proteine in vivo i mišićne delije sisara. Životinje se imuniziraju injekcijom ovih DNK konstrukcija, nazvanih polinukleotidne vakcine ili PNV, u njihove mi'Side. U DNK titraciji nadeno je da jedna imunizacija od. 0.5 "F128M".m"F255D".g fledne PNV daje 90% serokonverzije za deset nedelja posle imunizacije. Imuni antiserumi neutralist i HSV-2 i HSV-1 u ćelijskoj kulturi. Kad se životinje izazovu sa HSV-2 postignuta je značajna (p .001) zaštita od letalne infekcije posle PNV vakcinacije.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US27945994A | 1994-07-22 | 1994-07-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
YU49995A true YU49995A (sh) | 1998-05-15 |
Family
ID=23069059
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU49995A YU49995A (sh) | 1994-07-22 | 1995-07-21 | Polinukleotidna vakcina za virus herpesa |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP0772680A1 (sh) |
JP (1) | JPH10503649A (sh) |
AU (1) | AU708460B2 (sh) |
CA (1) | CA2195099A1 (sh) |
CO (1) | CO4410257A1 (sh) |
HR (1) | HRP950412A2 (sh) |
IL (1) | IL114576A0 (sh) |
WO (1) | WO1996003510A1 (sh) |
YU (1) | YU49995A (sh) |
ZA (1) | ZA956106B (sh) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5849719A (en) * | 1993-08-26 | 1998-12-15 | The Regents Of The University Of California | Method for treating allergic lung disease |
AU738835B2 (en) * | 1994-07-22 | 2001-09-27 | Merck & Co., Inc. | A polynucleotide herpes virus vaccine |
US7094767B2 (en) | 1994-07-22 | 2006-08-22 | Merck & Co., Inc. | Polynucleotide herpes virus vaccine |
CA2267645A1 (en) * | 1996-10-01 | 1998-04-09 | Merck & Co., Inc. | A polynucleotide herpes virus vaccine |
JP2001503257A (ja) * | 1996-10-18 | 2001-03-13 | バレンティス・インコーポレーテッド | Il―12遺伝子発現および送達系および使用 |
AU4908197A (en) * | 1996-10-18 | 1998-05-15 | Valentis, Inc. | Gene expression and delivery systems and uses |
GB9720633D0 (en) * | 1997-09-29 | 1997-11-26 | Univ Bristol | BHV-2 vector |
JP2002502884A (ja) * | 1998-02-12 | 2002-01-29 | アメリカン・サイアナミド・カンパニー | インターロイキン−12および単純ヘルペスウイルス抗原を含んでなるワクチン |
US6867000B2 (en) * | 2000-12-07 | 2005-03-15 | Wyeth Holdings Corporation | Method of enhancing immune responses to herpes |
US9012349B1 (en) | 2013-11-01 | 2015-04-21 | Ut-Battelle Llc | Method of synthesizing bulk transition metal carbide, nitride and phosphide catalysts |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3751664T2 (de) * | 1986-08-01 | 1996-06-05 | Commw Scient Ind Res Org | Rekombinanter impfstoff |
ATE240401T1 (de) * | 1989-03-21 | 2003-05-15 | Vical Inc | Expression von exogenen polynukleotidsequenzen in wirbeltieren |
ATE123065T1 (de) * | 1989-07-07 | 1995-06-15 | Takeda Chemical Industries Ltd | Proteine und deren herstellung. |
-
1995
- 1995-07-12 IL IL11457695A patent/IL114576A0/xx unknown
- 1995-07-18 CA CA002195099A patent/CA2195099A1/en not_active Abandoned
- 1995-07-18 EP EP95926736A patent/EP0772680A1/en not_active Withdrawn
- 1995-07-18 JP JP8505831A patent/JPH10503649A/ja not_active Withdrawn
- 1995-07-18 CO CO95031727A patent/CO4410257A1/es unknown
- 1995-07-18 HR HR08/279,459A patent/HRP950412A2/hr not_active Application Discontinuation
- 1995-07-18 WO PCT/US1995/009057 patent/WO1996003510A1/en not_active Application Discontinuation
- 1995-07-18 AU AU31012/95A patent/AU708460B2/en not_active Ceased
- 1995-07-21 YU YU49995A patent/YU49995A/sh unknown
- 1995-07-21 ZA ZA956106A patent/ZA956106B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
JPH10503649A (ja) | 1998-04-07 |
WO1996003510A1 (en) | 1996-02-08 |
AU708460B2 (en) | 1999-08-05 |
IL114576A0 (en) | 1995-11-27 |
ZA956106B (en) | 1996-04-10 |
HRP950412A2 (en) | 1997-10-31 |
CA2195099A1 (en) | 1996-02-08 |
CO4410257A1 (es) | 1997-01-09 |
AU3101295A (en) | 1996-02-22 |
EP0772680A1 (en) | 1997-05-14 |
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