YU49215B - Primena flupirtina za dobijanje medikamenta za tretman neurodegenerativnih oboljenja - Google Patents
Primena flupirtina za dobijanje medikamenta za tretman neurodegenerativnih oboljenjaInfo
- Publication number
- YU49215B YU49215B YU51294A YU51294A YU49215B YU 49215 B YU49215 B YU 49215B YU 51294 A YU51294 A YU 51294A YU 51294 A YU51294 A YU 51294A YU 49215 B YU49215 B YU 49215B
- Authority
- YU
- Yugoslavia
- Prior art keywords
- medicament
- treatment
- flupirtine
- prepare
- neurodegenerative diseases
- Prior art date
Links
- JUUFBMODXQKSTD-UHFFFAOYSA-N N-[2-amino-6-[(4-fluorophenyl)methylamino]-3-pyridinyl]carbamic acid ethyl ester Chemical compound N1=C(N)C(NC(=O)OCC)=CC=C1NCC1=CC=C(F)C=C1 JUUFBMODXQKSTD-UHFFFAOYSA-N 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- 229960003667 flupirtine Drugs 0.000 title abstract 2
- 230000004770 neurodegeneration Effects 0.000 title 1
- 208000015122 neurodegenerative disease Diseases 0.000 title 1
- 201000006474 Brain Ischemia Diseases 0.000 abstract 1
- 206010008120 Cerebral ischaemia Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 206010008118 cerebral infarction Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Confectionery (AREA)
- Medicinal Preparation (AREA)
Abstract
Primena aktivnog sastojka flupirtina za dobijanje medikamenta za lečenje cerebralne ishemije. Prljava sadrži još 11 nezavisnih zahteva.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4327516A DE4327516A1 (de) | 1993-08-17 | 1993-08-17 | Primäre und sekundäre neuroprotektive Wirkung bei neurodegenerativen Erkrankungen von Flupirtin |
Publications (2)
Publication Number | Publication Date |
---|---|
YU51294A YU51294A (sh) | 1998-05-15 |
YU49215B true YU49215B (sh) | 2004-11-25 |
Family
ID=6495312
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU51294A YU49215B (sh) | 1993-08-17 | 1994-08-15 | Primena flupirtina za dobijanje medikamenta za tretman neurodegenerativnih oboljenja |
Country Status (27)
Country | Link |
---|---|
US (1) | US5721258A (sh) |
EP (1) | EP0716602B1 (sh) |
JP (1) | JPH09501664A (sh) |
KR (1) | KR100341952B1 (sh) |
CN (1) | CN1086291C (sh) |
AT (1) | ATE210442T1 (sh) |
AU (1) | AU694447B2 (sh) |
BG (1) | BG62430B1 (sh) |
BR (1) | BR9407293A (sh) |
CA (1) | CA2169718C (sh) |
CZ (1) | CZ289040B6 (sh) |
DE (2) | DE4327516A1 (sh) |
DK (1) | DK0716602T3 (sh) |
EE (1) | EE03204B1 (sh) |
ES (1) | ES2168309T3 (sh) |
HR (1) | HRP940464A2 (sh) |
HU (1) | HU227765B1 (sh) |
IL (1) | IL110681A (sh) |
NO (1) | NO309842B1 (sh) |
NZ (1) | NZ273292A (sh) |
PT (1) | PT716602E (sh) |
RU (1) | RU2166318C2 (sh) |
SK (1) | SK283330B6 (sh) |
UA (1) | UA43351C2 (sh) |
WO (1) | WO1995005175A1 (sh) |
YU (1) | YU49215B (sh) |
ZA (1) | ZA946176B (sh) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19539861A1 (de) * | 1995-10-26 | 1997-04-30 | Asta Medica Ag | Verwendung von 4-Amino-4-(4-fluorbenzylamino)-1-ethoxy-carbonylaminobenzen zur Prophylaxe und Behandlung der Folgen der akuten und chronischen zerebralen Minderdurchblutung sowie neurodegenerativer Erkrankungen |
DE19541405A1 (de) * | 1995-11-07 | 1997-05-15 | Asta Medica Ag | Verwendung von Flupirtin zur Prophylaxe und Therapie von Erkrankungen, die mit einer Beeinträchtigung des hämatopoetischen Zellsystems einhergehen |
DE19625582A1 (de) * | 1996-06-27 | 1998-01-02 | Asta Medica Ag | Verwendung von Flupirtin zur Prophylaxe und Therapie von Erkrankungen die mit einer unphysiologisch hohen Zellsterberate einhergehen |
EP1034783B1 (en) * | 1997-10-27 | 2004-12-15 | Sumitomo Pharmaceuticals Company, Limited | Amide derivatives for the treatment of retinal neurodegenerative disorders |
WO2001034172A2 (en) * | 1999-11-05 | 2001-05-17 | Vela Pharmaceuticals Inc. | Methods and compositions for treating reward deficiency syndrome |
US6821995B1 (en) | 1999-12-01 | 2004-11-23 | Duke University | Method of treating batten disease |
AU1353901A (en) * | 1999-12-01 | 2001-06-12 | Duke University | Method of treating batten disease |
DE10327674A1 (de) | 2003-06-20 | 2005-01-05 | Awd.Pharma Gmbh & Co. Kg | Injizierbare Darreichungsform von Flupirtin |
DE10328260A1 (de) * | 2003-06-23 | 2005-01-27 | Schmidt, K.-G., Dr. med. | Flupirtine-Präparat |
CA2550023C (en) * | 2003-12-16 | 2011-04-12 | Cnsbio Pty Ltd | Treatment of neuropathic pain |
US20080287399A1 (en) * | 2004-12-14 | 2008-11-20 | Astrazeneca Ab | Substituted Aminopyridines and Uses Thereof |
EP1688141A1 (en) | 2005-01-31 | 2006-08-09 | elbion AG | The use of flupirtine for the treatment of overactive bladder and associated diseases, and for the treatment of irritable bowel syndrome |
US20060258708A1 (en) * | 2005-05-16 | 2006-11-16 | Andrulis Peter J Jr | Method for treating Parkinson's disease and other neurological diseases |
US20080279930A1 (en) * | 2007-05-07 | 2008-11-13 | Bernd Terhaag | Controlled-Release Flupirtine Compositions, Compacts, Kits and Methods of Making and Use Thereof |
DE102011006425A1 (de) | 2010-03-31 | 2011-10-06 | Awd.Pharma Gmbh & Co. Kg | Pharmazeutische Zubereitung und deren Verwendung |
DE102010030053A1 (de) | 2010-06-14 | 2011-12-15 | Awd.Pharma Gmbh & Co.Kg | Injizierbare Darreichungsform von Flupirtin |
MX2016001177A (es) * | 2013-07-31 | 2016-04-29 | Teva Pharma | Tratamiento de esclerosis multiple con la combinacion de laquinimod y flupirtina. |
US11369593B2 (en) * | 2017-07-14 | 2022-06-28 | Texas Tech University System | Functionalized pyridine carbamates with enhanced neuroprotective activity |
DE102017007385A1 (de) | 2017-08-02 | 2019-02-07 | Christoph Hoock | Maleatfreie feste Arzneimittelformen |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4481205A (en) * | 1980-09-13 | 1984-11-06 | Degussa Aktiengesellschaft | 2-Amino-3-carbethoxyamino-6-(p-fluoro-benzylamino)-pyridine-maleate |
DE3337593A1 (de) * | 1982-10-27 | 1984-05-03 | Degussa Ag, 6000 Frankfurt | 2-amino-3-acylamino-6-benzylamino-pyridin-derivate mit antiepileptischer wirkung |
EP0110091B1 (de) * | 1982-10-27 | 1987-01-21 | Degussa Aktiengesellschaft | 2-Amino-3-Acylamino-6-benzylamino-pyridin-Derivate mit anti-epileptischer Wirkung |
NO860825L (no) * | 1985-03-23 | 1986-09-24 | Degussa | Fremgangsmaate til fremstilling av 2-amino-3-nitro-6-(4-fluor-benzylamino)-pyridin samt 2-amino-3-karbetoksyamino-6-(4-fluor-benzylamino)-pyridin. |
IN172468B (sh) * | 1990-07-14 | 1993-08-14 | Asta Medica Ag |
-
1993
- 1993-08-17 DE DE4327516A patent/DE4327516A1/de not_active Ceased
-
1994
- 1994-08-10 CZ CZ1996465A patent/CZ289040B6/cs not_active IP Right Cessation
- 1994-08-10 NZ NZ273292A patent/NZ273292A/en not_active IP Right Cessation
- 1994-08-10 EP EP94926828A patent/EP0716602B1/en not_active Expired - Lifetime
- 1994-08-10 BR BR9407293A patent/BR9407293A/pt not_active Application Discontinuation
- 1994-08-10 KR KR1019960700753A patent/KR100341952B1/ko active IP Right Grant
- 1994-08-10 WO PCT/EP1994/002649 patent/WO1995005175A1/en active IP Right Grant
- 1994-08-10 RU RU96105707/14A patent/RU2166318C2/ru active
- 1994-08-10 ES ES94926828T patent/ES2168309T3/es not_active Expired - Lifetime
- 1994-08-10 JP JP7506731A patent/JPH09501664A/ja active Pending
- 1994-08-10 SK SK214-96A patent/SK283330B6/sk not_active IP Right Cessation
- 1994-08-10 DK DK94926828T patent/DK0716602T3/da active
- 1994-08-10 AU AU76528/94A patent/AU694447B2/en not_active Expired
- 1994-08-10 DE DE69429435T patent/DE69429435T2/de not_active Expired - Lifetime
- 1994-08-10 CN CN94193106A patent/CN1086291C/zh not_active Expired - Lifetime
- 1994-08-10 PT PT94926828T patent/PT716602E/pt unknown
- 1994-08-10 CA CA002169718A patent/CA2169718C/en not_active Expired - Lifetime
- 1994-08-10 US US08/602,742 patent/US5721258A/en not_active Expired - Lifetime
- 1994-08-10 HU HU9600355A patent/HU227765B1/hu unknown
- 1994-08-10 AT AT94926828T patent/ATE210442T1/de active
- 1994-08-15 YU YU51294A patent/YU49215B/sh unknown
- 1994-08-16 ZA ZA946176A patent/ZA946176B/xx unknown
- 1994-08-16 IL IL11068194A patent/IL110681A/xx not_active IP Right Cessation
- 1994-08-16 HR HRP4327516.8A patent/HRP940464A2/hr not_active Application Discontinuation
- 1994-10-08 UA UA96030972A patent/UA43351C2/uk unknown
- 1994-10-25 EE EE9400160A patent/EE03204B1/xx unknown
-
1996
- 1996-02-14 BG BG100356A patent/BG62430B1/bg unknown
- 1996-02-15 NO NO960607A patent/NO309842B1/no not_active IP Right Cessation
Also Published As
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