YU41968B - Process for obtaining hypoglycemic guanylamidines - Google Patents
Process for obtaining hypoglycemic guanylamidinesInfo
- Publication number
- YU41968B YU41968B YU398/81A YU39881A YU41968B YU 41968 B YU41968 B YU 41968B YU 398/81 A YU398/81 A YU 398/81A YU 39881 A YU39881 A YU 39881A YU 41968 B YU41968 B YU 41968B
- Authority
- YU
- Yugoslavia
- Prior art keywords
- guanylamidines
- hypoglycemic
- obtaining
- obtaining hypoglycemic
- hypoglycemic guanylamidines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/53—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Furan Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/122,155 US4269837A (en) | 1980-02-19 | 1980-02-19 | Hypoglycemic guanylamidines, compositions and use |
Publications (2)
Publication Number | Publication Date |
---|---|
YU39881A YU39881A (en) | 1983-09-30 |
YU41968B true YU41968B (en) | 1988-04-30 |
Family
ID=22401029
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU398/81A YU41968B (en) | 1980-02-19 | 1981-02-17 | Process for obtaining hypoglycemic guanylamidines |
Country Status (18)
Country | Link |
---|---|
US (1) | US4269837A (de) |
EP (1) | EP0034495B1 (de) |
JP (1) | JPS56147760A (de) |
KR (1) | KR840000930B1 (de) |
AR (1) | AR229350A1 (de) |
AT (1) | ATE3425T1 (de) |
AU (1) | AU517843B2 (de) |
CA (1) | CA1145334A (de) |
DE (1) | DE3160290D1 (de) |
DK (1) | DK70881A (de) |
ES (1) | ES499572A0 (de) |
FI (1) | FI75343C (de) |
GR (1) | GR78339B (de) |
IE (1) | IE50924B1 (de) |
IL (1) | IL62146A (de) |
PH (1) | PH15971A (de) |
PT (1) | PT72516B (de) |
YU (1) | YU41968B (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4404219A (en) * | 1980-03-31 | 1983-09-13 | Pfizer Inc. | Phenylguanidine therapeutic agents |
US5268373A (en) * | 1992-07-28 | 1993-12-07 | Mcneilab, Inc. | Guanidine derivatives, compositions and use |
PT805153E (pt) * | 1996-04-30 | 2002-03-28 | Pfizer | Novos agonistas do receptor muscarinico |
AR008290A1 (es) * | 1996-08-15 | 1999-12-29 | Smithkline Beecham Corp | Nuevos compuestos que contienen guanidina utiles como antagonistas de los receptores de il-8, composiciones farmaceuticas que los contienenprocedimiento para la preparacion de dichos compuestos y procedimiento para la preparacion de intermediarios. |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH478802A (de) | 1966-09-06 | 1969-09-30 | Sandoz Ag | Verfahren zur Herstellung von Pyrazolderivaten |
CS225804B2 (cs) | 1976-03-19 | 1984-02-13 | Mcneilab Inc | Způsob výroby heterocyklických derivátů guanidinu |
-
1980
- 1980-02-19 US US06/122,155 patent/US4269837A/en not_active Expired - Lifetime
-
1981
- 1981-02-16 GR GR64154A patent/GR78339B/el unknown
- 1981-02-16 AR AR284300A patent/AR229350A1/es active
- 1981-02-16 JP JP2133581A patent/JPS56147760A/ja active Granted
- 1981-02-17 AT AT81300634T patent/ATE3425T1/de not_active IP Right Cessation
- 1981-02-17 EP EP81300634A patent/EP0034495B1/de not_active Expired
- 1981-02-17 YU YU398/81A patent/YU41968B/xx unknown
- 1981-02-17 PT PT72516A patent/PT72516B/pt unknown
- 1981-02-17 IE IE311/81A patent/IE50924B1/en unknown
- 1981-02-17 DE DE8181300634T patent/DE3160290D1/de not_active Expired
- 1981-02-17 CA CA000371114A patent/CA1145334A/en not_active Expired
- 1981-02-17 IL IL62146A patent/IL62146A/xx unknown
- 1981-02-18 FI FI810492A patent/FI75343C/fi not_active IP Right Cessation
- 1981-02-18 DK DK70881A patent/DK70881A/da not_active Application Discontinuation
- 1981-02-18 KR KR1019810000507A patent/KR840000930B1/ko active
- 1981-02-18 AU AU67408/81A patent/AU517843B2/en not_active Ceased
- 1981-02-18 ES ES499572A patent/ES499572A0/es active Granted
- 1981-02-19 PH PH25233A patent/PH15971A/en unknown
Also Published As
Publication number | Publication date |
---|---|
FI810492L (fi) | 1981-08-20 |
ATE3425T1 (de) | 1983-06-15 |
AR229350A1 (es) | 1983-07-29 |
IL62146A (en) | 1984-09-30 |
FI75343B (fi) | 1988-02-29 |
EP0034495A2 (de) | 1981-08-26 |
JPS6348265B2 (de) | 1988-09-28 |
DK70881A (da) | 1981-08-20 |
CA1145334A (en) | 1983-04-26 |
EP0034495B1 (de) | 1983-05-18 |
YU39881A (en) | 1983-09-30 |
PT72516B (en) | 1982-10-21 |
GR78339B (de) | 1984-09-26 |
PH15971A (en) | 1983-05-11 |
KR840000930B1 (ko) | 1984-06-29 |
FI75343C (fi) | 1988-06-09 |
US4269837A (en) | 1981-05-26 |
DE3160290D1 (en) | 1983-07-07 |
IE810311L (en) | 1981-08-19 |
PT72516A (en) | 1981-03-01 |
IL62146A0 (en) | 1981-03-31 |
ES8201541A1 (es) | 1981-12-16 |
KR830005188A (ko) | 1983-08-03 |
IE50924B1 (en) | 1986-08-20 |
ES499572A0 (es) | 1981-12-16 |
JPS56147760A (en) | 1981-11-16 |
EP0034495A3 (en) | 1982-01-27 |
AU517843B2 (en) | 1981-08-27 |
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