YU34876B - Process for obtaining novel n-substituted pyrrolidines - Google Patents
Process for obtaining novel n-substituted pyrrolidinesInfo
- Publication number
- YU34876B YU34876B YU306/71A YU30671A YU34876B YU 34876 B YU34876 B YU 34876B YU 306/71 A YU306/71 A YU 306/71A YU 30671 A YU30671 A YU 30671A YU 34876 B YU34876 B YU 34876B
- Authority
- YU
- Yugoslavia
- Prior art keywords
- obtaining novel
- substituted pyrrolidines
- pyrrolidines
- substituted
- novel
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
- C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB697870A GB1309692A (en) | 1970-02-13 | 1970-02-13 | N-substituted lactams |
Publications (2)
Publication Number | Publication Date |
---|---|
YU30671A YU30671A (en) | 1979-10-31 |
YU34876B true YU34876B (en) | 1980-04-30 |
Family
ID=9824325
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU306/71A YU34876B (en) | 1970-02-13 | 1971-02-10 | Process for obtaining novel n-substituted pyrrolidines |
YU01445/78A YU144578A (en) | 1970-02-13 | 1978-06-19 | Process for obtaining new n-substituted pyrrolidones |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU01445/78A YU144578A (en) | 1970-02-13 | 1978-06-19 | Process for obtaining new n-substituted pyrrolidones |
Country Status (15)
Country | Link |
---|---|
JP (2) | JPS535301B1 (en) |
BE (1) | BE762728R (en) |
CH (1) | CH530395A (en) |
CS (2) | CS167911B2 (en) |
DE (1) | DE2106418C2 (en) |
DK (1) | DK137451B (en) |
ES (1) | ES388135A2 (en) |
FI (1) | FI54916C (en) |
FR (1) | FR2081508B2 (en) |
GB (1) | GB1309692A (en) |
MY (1) | MY7400072A (en) |
NL (1) | NL168830C (en) |
SU (2) | SU508186A3 (en) |
YU (2) | YU34876B (en) |
ZA (1) | ZA71877B (en) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1045043B (en) * | 1975-08-13 | 1980-04-21 | Isf Spa | PYROLIDINE DERIVATIVES |
GB1583871A (en) * | 1976-10-19 | 1981-02-04 | Ucb Sa | Anti-aggregants |
BE864269A (en) * | 1977-03-03 | 1978-06-16 | Parke Davis & Co | NEW N- (AMINOALKYL SUBSTITUTE) -2-OXO-1-PYRROLIDINE-ACETAMIDES AND METHODS FOR PRODUCING THEM |
ATE27T1 (en) | 1978-05-08 | 1981-04-15 | Ucb Sa | LACTAM-N-ACETIC ACIDS AND THEIR AMIDES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM |
IT1141287B (en) * | 1979-06-13 | 1986-10-01 | Nattermann A & Cie | PYROLIDIN ACIDS AMIDS- (2) -ON- (1) -ILALKYL-CARBOXYLS, PROCEDURE FOR THEIR PREPARATION AND MEDICINAL PRODUCTS CONTAINING THEM |
FR2515179A1 (en) * | 1981-07-24 | 1983-04-29 | Hoffmann La Roche | PYRROLIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, INTERMEDIATES FOR THEIR SYNTHESIS AND THEIR THERAPEUTIC APPLICATION |
DE3361609D1 (en) * | 1982-03-24 | 1986-02-06 | Prodes Sa | New n-((2-oxo-1-pyrrolidinyl)acetyl)piperazines, the methods of producing such new compounds and their salts as well as pharmaceutical preparations for therapeutic use containing these compounds or salts |
GB8412358D0 (en) * | 1984-05-15 | 1984-06-20 | Ucb Sa | Pharmaceutical composition |
GB8412357D0 (en) * | 1984-05-15 | 1984-06-20 | Ucb Sa | Pharmaceutical composition |
DE3420193A1 (en) * | 1984-05-30 | 1985-12-05 | Boehringer Ingelheim KG, 6507 Ingelheim | NEW SUBSTITUTED PYRROLIDINONES, METHOD FOR THEIR PRODUCTION AND MEDICINAL PRODUCTS |
US4804400A (en) * | 1986-09-12 | 1989-02-14 | Ciba-Geigy Corporation | N-phenyl-maleimides and herbicidal and plant growth regulating methods of use thereof |
GB8827389D0 (en) * | 1988-11-23 | 1988-12-29 | Ucb Sa | Process for preparation of(s)alpha-ethyl-2-oxo-1-pyrrolidineacetamide |
TW544311B (en) * | 1998-08-06 | 2003-08-01 | Daiichi Seiyaku Co | Therapeutic or preventive agent for intractable epilepsies |
GB0004297D0 (en) * | 2000-02-23 | 2000-04-12 | Ucb Sa | 2-oxo-1 pyrrolidine derivatives process for preparing them and their uses |
US6686477B2 (en) | 2000-09-29 | 2004-02-03 | Eastman Chemical Company | Highly enantiomerically pure lactam-substituted propanoic acid derivatives and methods of making and using same |
WO2002094787A1 (en) * | 2001-05-23 | 2002-11-28 | Ucb, S.A. | 2-oxo-piperidinyl- and 2-oxo-azepanyl alkanoic acid derivativ es for the treatment of epilepsy and other neurological disorders |
IL160045A0 (en) | 2001-08-10 | 2004-06-20 | Ucb Sa | Oxopyrrolidine compounds, preparation of said compounds and their use in the manufacturing of levetiracetam and analogues |
CA2461961A1 (en) * | 2001-10-08 | 2003-04-17 | Ucb, S.A. | Use of 2-oxo-1-pyrrolidine derivatives for the treatment of dyskinesia and movement disorders |
US7132552B2 (en) | 2003-02-03 | 2006-11-07 | Teva Pharmaceutical Industries, Ltd. | Process for producing levetiracetam |
ES2214147B1 (en) * | 2003-02-28 | 2005-10-01 | Farma-Lepori S.A. | PROCEDURE FOR OBTAINING AN ANTIEPILEPTIC AGENT. |
US7531673B2 (en) | 2004-02-18 | 2009-05-12 | Dr. Reddy's Laboratories Limited | Preparation of amino acid amides |
CA2488325C (en) | 2004-11-22 | 2010-08-24 | Apotex Pharmachem Inc. | Improved process for the preparation of (s)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide and (r)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide |
EP1863761A1 (en) * | 2005-03-10 | 2007-12-12 | Rubamin Limited | Process for preparing levetiracetam |
EP2308870A3 (en) | 2005-06-01 | 2011-10-19 | UCB Pharma S.A. | 2-oxo-1-pyrrolidine deriatives, processes for preparing them and their uses |
EP2147911A1 (en) | 2008-07-24 | 2010-01-27 | ZaCh System S.p.A. | Process for the preparation of levetiracetam |
CN102227217A (en) | 2008-10-16 | 2011-10-26 | 约翰斯.霍普金斯大学 | Methods and compositions for improving cognitive function |
US8785661B2 (en) | 2009-05-13 | 2014-07-22 | Nektar Therapeutics | Oligome-containing pyrrolidine compounds |
US7939676B2 (en) | 2009-09-17 | 2011-05-10 | Zach System S.P.A. | Process for the preparation of levetiracetam |
EA037187B1 (en) | 2010-02-09 | 2021-02-17 | Дзе Джонс Хопкинс Юниверсити | Method and composition for treating a cognitive disorder |
US10154988B2 (en) | 2012-11-14 | 2018-12-18 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
WO2014144663A1 (en) | 2013-03-15 | 2014-09-18 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
WO2014144801A1 (en) | 2013-03-15 | 2014-09-18 | Agenebio Inc. | Methods and compositions for improving cognitive function |
WO2015110435A1 (en) | 2014-01-21 | 2015-07-30 | Janssen Pharmaceutica Nv | Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use |
LT3096790T (en) | 2014-01-21 | 2019-10-10 | Janssen Pharmaceutica, N.V. | Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use |
CN104059010A (en) * | 2014-06-12 | 2014-09-24 | 浙江华海药业股份有限公司 | Preparation method of 2-(2-oxopyrrolidine-1-yl)-butyrate |
CN106591179B (en) * | 2016-12-05 | 2018-07-03 | 长兴制药股份有限公司 | Methyl packing bacterium and its prepare the application on (S)-α-ethyl -2- oxygen -1- pyrrolidine acetic acid salt in selective fractionation |
RU2663899C1 (en) * | 2017-07-19 | 2018-08-13 | Федеральное государственное унитарное предприятие "Государственный научный центр "Научно-исследовательский институт органических полупродуктов и красителей" | Process for the preparation of 1-carbamoylmethyl-4-phenyl-2-pyrrolidone |
US11384050B1 (en) | 2021-02-03 | 2022-07-12 | Vitaworks Ip, Llc | Method for preparing levetiracetam and intermediates thereof |
US20240132513A1 (en) | 2022-08-19 | 2024-04-25 | Agenebio, Inc. | Benzazepine derivatives, compositions, and methods for treating cognitive impairment |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1039113A (en) * | 1964-08-06 | 1966-08-17 | Ucb Sa | New n-substituted lactams |
-
1970
- 1970-02-13 GB GB697870A patent/GB1309692A/en not_active Expired
-
1971
- 1971-02-08 FR FR7104195A patent/FR2081508B2/fr not_active Expired
- 1971-02-09 NL NLAANVRAGE7101697,A patent/NL168830C/en not_active IP Right Cessation
- 1971-02-10 YU YU306/71A patent/YU34876B/en unknown
- 1971-02-10 DK DK59571AA patent/DK137451B/en not_active IP Right Cessation
- 1971-02-10 CS CS987A patent/CS167911B2/cs unknown
- 1971-02-10 BE BE762728A patent/BE762728R/en active
- 1971-02-10 FI FI383/71A patent/FI54916C/en active
- 1971-02-10 ES ES388135A patent/ES388135A2/en not_active Expired
- 1971-02-11 CH CH200171A patent/CH530395A/en not_active IP Right Cessation
- 1971-02-11 ZA ZA710877A patent/ZA71877B/en unknown
- 1971-02-11 DE DE2106418A patent/DE2106418C2/en not_active Expired
- 1971-02-12 JP JP612471A patent/JPS535301B1/ja active Pending
- 1971-02-12 SU SU1893858A patent/SU508186A3/en active
- 1971-02-12 SU SU1621307A patent/SU508185A3/en active
- 1971-12-10 CS CS140674A patent/CS167912B2/cs unknown
-
1974
- 1974-12-31 MY MY197472A patent/MY7400072A/en unknown
-
1977
- 1977-11-07 JP JP13335277A patent/JPS53130656A/en active Granted
-
1978
- 1978-06-19 YU YU01445/78A patent/YU144578A/en unknown
Also Published As
Publication number | Publication date |
---|---|
YU144578A (en) | 1982-10-31 |
CH530395A (en) | 1972-11-15 |
SU508185A3 (en) | 1976-03-25 |
NL168830C (en) | 1982-05-17 |
JPS535301B1 (en) | 1978-02-25 |
FR2081508B2 (en) | 1975-06-06 |
DE2106418A1 (en) | 1971-08-19 |
MY7400072A (en) | 1974-12-31 |
DK137451B (en) | 1978-03-06 |
CS167911B2 (en) | 1976-05-28 |
DE2106418C2 (en) | 1983-12-22 |
FI54916C (en) | 1979-04-10 |
SU508186A3 (en) | 1976-03-25 |
ES388135A2 (en) | 1973-05-01 |
CS167912B2 (en) | 1976-05-28 |
NL7101697A (en) | 1971-08-17 |
YU30671A (en) | 1979-10-31 |
DK137451C (en) | 1978-07-24 |
JPS5420491B2 (en) | 1979-07-23 |
JPS53130656A (en) | 1978-11-14 |
FR2081508A2 (en) | 1971-12-03 |
FI54916B (en) | 1978-12-29 |
GB1309692A (en) | 1973-03-14 |
ZA71877B (en) | 1971-10-27 |
BE762728R (en) | 1971-08-10 |
NL168830B (en) | 1981-12-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
YU30671A (en) | Process for obtaining novel n-substituted pyrrolidines | |
YU191271A (en) | Process for obtaining novel substituted phenyl-pyrrolidones | |
JPS53149921A (en) | Process for preparing diesterdiamide | |
JPS5436230A (en) | Process for preparing substituted halophenylacetic amide | |
EG10628A (en) | Process for making 7-halolincomycin | |
ZA714007B (en) | Lactam process | |
YU35866B (en) | Process for obtaining benzobicycloalkane amines | |
YU250078A (en) | Process for preparing phenylaminoalkanes | |
YU188374A (en) | Process for obtaining n-substituted p-amino-3-nitro-benzophenones | |
ZA711022B (en) | Process for preparing novel substituted quinoxaline-di-oxides | |
JPS53116397A (en) | Process for preparing imidazoleeribocyclophosphate | |
IL36143A0 (en) | Process for preparing n-alkyl-dimethylamines | |
YU260071A (en) | Process for preparing novel quinazolone-diurethanes | |
YU37160B (en) | Process for obtaining n-substituted cycloserines | |
YU34786B (en) | Process for preparing des-phenylalanine-bi-insulin | |
YU34139B (en) | Process for preparing 9alfa-chloro-11beta-hydroxy-3-keto-delta-4-pregnenes | |
YU268371A (en) | Process for preparing delta-substituted 2-aminomethylbenzylalcohols | |
YU34114B (en) | Process for preparing n-substituted acetaldimines | |
CS194182B2 (en) | Process for preparing n-substituted beta-amino-alpha benylacrylonitriles | |
YU34672B (en) | Process for preparing 1-ethyl-2-amino-methyl pyrrolidine | |
RO72550B (en) | Process for preparing thiolcarbamates | |
YU166071A (en) | Process for preparing novel substituted phenyl-thiol-carbamates | |
YU195871A (en) | Process for preparing thiadiazolyl-carbamides | |
CS194180B2 (en) | Process for preparing n-substituted beta-amino-alpha-benzylacrylonitriles | |
CS194152B2 (en) | Process for preparing n-substituted beta-amino-alpha-benzylacrylonitriles |