YU216177A - Process for preparing 2-bromo ergosine - Google Patents
Process for preparing 2-bromo ergosineInfo
- Publication number
- YU216177A YU216177A YU02161/77A YU216177A YU216177A YU 216177 A YU216177 A YU 216177A YU 02161/77 A YU02161/77 A YU 02161/77A YU 216177 A YU216177 A YU 216177A YU 216177 A YU216177 A YU 216177A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- ergosine
- bromo
- preparing
- bromo ergosine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/02—Ergot alkaloids of the cyclic peptide type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
YU02161/77A YU216177A (en) | 1977-09-09 | 1977-09-09 | Process for preparing 2-bromo ergosine |
US05/932,386 US4219555A (en) | 1977-09-09 | 1978-08-09 | 2-Bromoergosine and pharmacologically compatible acid addition salts thereof as well as their use for the treatment of arterial hypertension and or heart arrythmias |
PT68447A PT68447A (en) | 1977-09-09 | 1978-08-18 | 2-bromoergosine and its acid addition salts a process for the preparation thereof and their use in medicines |
ES472847A ES472847A1 (es) | 1977-09-09 | 1978-08-25 | Procedimiento para la preparacion de la 2-bromoergosina y sus sales acidas de adicion |
FI782666A FI782666A (fi) | 1977-09-09 | 1978-08-31 | 2-bromergosin och dess syraadditions salter dess framstaellningsfoerfarande och anvaendning av dessa foereningar i laekemedel |
CS785746A CS207666B2 (en) | 1977-09-09 | 1978-09-05 | Method of making the 2-bromergosin and the additive salts thereof with the acid |
EP78100835A EP0001115A3 (de) | 1977-09-09 | 1978-09-06 | 2-Bromergosin und seine Säureadditionssalze, Verfahren zu deren Herstellung sowie deren Verwendung als Heilmittel |
SU792732105A SU891674A1 (ru) | 1977-09-09 | 1979-02-28 | 2-Бромэргозин или его аддитивно-кислые соли,про вл ющие гипотензивную активность |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
YU02161/77A YU216177A (en) | 1977-09-09 | 1977-09-09 | Process for preparing 2-bromo ergosine |
Publications (1)
Publication Number | Publication Date |
---|---|
YU216177A true YU216177A (en) | 1984-02-29 |
Family
ID=25557072
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU02161/77A YU216177A (en) | 1977-09-09 | 1977-09-09 | Process for preparing 2-bromo ergosine |
Country Status (8)
Country | Link |
---|---|
US (1) | US4219555A (xx) |
EP (1) | EP0001115A3 (xx) |
CS (1) | CS207666B2 (xx) |
ES (1) | ES472847A1 (xx) |
FI (1) | FI782666A (xx) |
PT (1) | PT68447A (xx) |
SU (1) | SU891674A1 (xx) |
YU (1) | YU216177A (xx) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
YU39786B (en) * | 1976-12-23 | 1985-04-30 | Lek Tovarna Farmacevtskih | Process for preparing 2-bromo-alfa-ergocriptine |
YU39849B (en) * | 1978-09-26 | 1985-04-30 | Lek Tovarna Farmacevtskih | Process for preparing 2-bromo-ergolene and 2-bromo-ergoline compounds |
US4609731A (en) * | 1979-10-10 | 1986-09-02 | Sandoz Ltd. | Process for brominating ergot alkaloids |
CH649300A5 (de) * | 1981-08-07 | 1985-05-15 | Sandoz Ag | Ergopeptinderivate, ihre herstellung und verwendung. |
DE3340025C2 (de) * | 1983-11-03 | 1986-01-09 | Schering AG, 1000 Berlin und 4709 Bergkamen | Verfahren zur Herstellung von 2-Brom-8-ergolinyl-Verbindungen |
GB8426922D0 (en) * | 1984-10-24 | 1984-11-28 | Sandoz Ltd | Galenic formulation |
GB2173189B (en) * | 1985-02-21 | 1988-04-27 | Maruko Pharmaceutical Co | Ergoline derivatives and salts thereof and pharmaceutical compositions thereof |
HU193317B (en) * | 1985-06-12 | 1987-09-28 | Richter Gedeon Vegyeszet | Process for producing 2-bromo-alpha-ergochristin |
HU196394B (en) * | 1986-06-27 | 1988-11-28 | Richter Gedeon Vegyeszet | Process for preparing 2-halogenated ergoline derivatives |
US5668155A (en) * | 1988-05-10 | 1997-09-16 | The General Hospital Corporation | Administration of pirenzepine, methyl scopolamine and other muscarinic receptor antagonists for treatment of lipid metabolism disorders |
US5585347A (en) * | 1988-05-10 | 1996-12-17 | Ergo Science Incorporated | Methods for the determination and adjustment of prolactin daily rhythms |
US5744477A (en) * | 1988-05-10 | 1998-04-28 | The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Method for treatment of obesity using prolactin modulators and diet |
US5830895A (en) * | 1988-05-10 | 1998-11-03 | The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Methods for the determination and adjustment of prolactin daily rhythms |
US5006526A (en) * | 1988-10-17 | 1991-04-09 | Louisiana State University | Method of treating a vertebrate animal to reduce plasma triglycerides and cholesterol levels and to alleviate and prevent atherosclerosis |
IL112106A0 (en) * | 1993-12-22 | 1995-03-15 | Ergo Science Inc | Accelerated release composition containing bromocriptine |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2497214A (en) * | 1946-03-18 | 1950-02-14 | William F Dreyer | Stud extractor tool |
FR7775M (xx) * | 1967-06-28 | 1970-03-23 | ||
CH507249A (de) * | 1968-05-31 | 1971-05-15 | Sandoz Ag | Verfahren zur Herstellung von 2-Brom-a-ergokryptin |
GB1298277A (en) * | 1969-04-18 | 1972-11-29 | Sandoz Ltd | Preparation of ergot peptide alkaloids |
US3920664A (en) * | 1972-07-21 | 1975-11-18 | Lilly Co Eli | D-2-halo-6-alkyl-8-substituted ergolines and related compounds |
US3883655A (en) * | 1973-10-11 | 1975-05-13 | Sandoz Ltd | Ergocornine or 2-bromo-{60 -ergocyptine in the treatment of parkinsonism |
US4138565A (en) * | 1975-05-31 | 1979-02-06 | Sandoz Ltd. | Stable solutions and processes for their preparation |
US4124712A (en) * | 1976-09-06 | 1978-11-07 | Sandoz Ltd. | Ergot peptide alkaloid derivatives |
YU39786B (en) | 1976-12-23 | 1985-04-30 | Lek Tovarna Farmacevtskih | Process for preparing 2-bromo-alfa-ergocriptine |
-
1977
- 1977-09-09 YU YU02161/77A patent/YU216177A/xx unknown
-
1978
- 1978-08-09 US US05/932,386 patent/US4219555A/en not_active Expired - Lifetime
- 1978-08-18 PT PT68447A patent/PT68447A/pt unknown
- 1978-08-25 ES ES472847A patent/ES472847A1/es not_active Expired
- 1978-08-31 FI FI782666A patent/FI782666A/fi unknown
- 1978-09-05 CS CS785746A patent/CS207666B2/cs unknown
- 1978-09-06 EP EP78100835A patent/EP0001115A3/de not_active Withdrawn
-
1979
- 1979-02-28 SU SU792732105A patent/SU891674A1/ru active
Also Published As
Publication number | Publication date |
---|---|
SU891674A1 (ru) | 1981-12-23 |
PT68447A (en) | 1978-09-01 |
EP0001115A3 (de) | 1979-04-04 |
FI782666A (fi) | 1979-03-10 |
ES472847A1 (es) | 1979-10-16 |
CS207666B2 (en) | 1981-08-31 |
US4219555A (en) | 1980-08-26 |
EP0001115A2 (de) | 1979-03-21 |
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