YU197387A - Process for producing izophamide-liophilizate - Google Patents

Process for producing izophamide-liophilizate

Info

Publication number
YU197387A
YU197387A YU01973/87A YU197387A YU197387A YU 197387 A YU197387 A YU 197387A YU 01973/87 A YU01973/87 A YU 01973/87A YU 197387 A YU197387 A YU 197387A YU 197387 A YU197387 A YU 197387A
Authority
YU
Yugoslavia
Prior art keywords
liophilizate
izophamide
producing
ifosfamide
weight
Prior art date
Application number
YU01973/87A
Inventor
D Sauerbier
U P Dammann
O Isaac
Original Assignee
Asta Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Pharma Ag filed Critical Asta Pharma Ag
Publication of YU197387A publication Critical patent/YU197387A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Control Of El Displays (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cephalosporin Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Indole Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Amplifiers (AREA)

Abstract

1. A lyophilized preparation consisting of ifosfamide and 0.1 to 17 parts by weight hexitol per part by weight ifosfamide and, optionally, other standard pharmaceutical auxiliaries.
YU01973/87A 1986-10-31 1987-10-30 Process for producing izophamide-liophilizate YU197387A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3637089 1986-10-31

Publications (1)

Publication Number Publication Date
YU197387A true YU197387A (en) 1988-12-31

Family

ID=6312873

Family Applications (1)

Application Number Title Priority Date Filing Date
YU01973/87A YU197387A (en) 1986-10-31 1987-10-30 Process for producing izophamide-liophilizate

Country Status (25)

Country Link
EP (1) EP0265812B1 (en)
JP (1) JPS63159319A (en)
KR (1) KR900003491B1 (en)
AT (1) ATE55250T1 (en)
AU (1) AU598602B2 (en)
CA (1) CA1314231C (en)
DD (1) DD262582A5 (en)
DE (1) DE3764235D1 (en)
DK (1) DK169308B1 (en)
EG (1) EG18333A (en)
ES (1) ES2017982B3 (en)
FI (1) FI87140C (en)
GE (1) GEP19971025B (en)
GR (1) GR3000708T3 (en)
HU (1) HU197987B (en)
IL (1) IL84312A (en)
IN (1) IN168119B (en)
LV (1) LV10051B (en)
MX (1) MX8958A (en)
NO (1) NO873860L (en)
PT (1) PT86032B (en)
RU (1) RU1836079C (en)
UA (1) UA11075A (en)
YU (1) YU197387A (en)
ZA (1) ZA878183B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE65402T1 (en) * 1988-03-19 1991-08-15 Asta Pharma Ag IFOSFAMIDE MESNA LYOPHILISATE AND PROCESS FOR PRODUCTION THEREOF.
US5227373A (en) * 1991-10-23 1993-07-13 Bristol-Myers Squibb Co. Lyophilized ifosfamide compositions
WO1995007083A1 (en) * 1993-09-10 1995-03-16 F.H. Faulding & Co. Limited Ifosfamide lyophilisate composition
DE19529057B4 (en) * 1995-08-08 2007-12-13 Baxter Healthcare S.A. Ifosfamide lyophilizate preparations
JP2002505282A (en) * 1998-03-03 2002-02-19 塩野義製薬株式会社 Pharmaceutical composition comprising the phospholipase inhibitor sodium [[3- (2-amino-1,2-dioxoethyl) -2-ethyl-1-phenylmethyl) -1H-indol-4-yl] oxy] acetate
BR0314068A (en) * 2002-09-05 2005-07-05 Bharat Serums & Vaccines Ltd Process for the preparation of a stable composition with low toxicity; stable composition containing oxazaphosphorin; use of a stable oxazaphosphorin-containing composition; and method of treatment of a malignant disease
JP4611029B2 (en) * 2002-12-02 2011-01-12 ブハラット セルムズ アンド ヴァクシンズ リミテッド Ifosfamide composition for parenteral administration and method for producing the same
US8436190B2 (en) * 2005-01-14 2013-05-07 Cephalon, Inc. Bendamustine pharmaceutical compositions
RU2470623C2 (en) * 2006-09-29 2012-12-27 Инфа С.А. Pharmaceutical composition container and kit for intravenous introduction
CN105900385B (en) * 2014-12-04 2019-08-27 华为技术有限公司 Load distribution in data communication network

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3732340A (en) * 1966-07-11 1973-05-08 Asta Werke Ag Chem Fab N',o-propylene phosphoric acid ester diamides
DE2750207A1 (en) * 1977-05-09 1978-11-16 Walton J Smith Anhydrous compsn. prodn. by freeze drying hydrated, hydrolysable prod. - esp. aspirin or aspirin salt solns.
EP0083439B1 (en) * 1981-12-31 1989-07-26 ASTA Pharma AG 4-sulfido-oxaza phosphorines and their use in the treatment of cancer, and in immunosuppression
US4537883A (en) * 1982-11-12 1985-08-27 Mead Johnson & Company Lyophilized cyclophosphamide

Also Published As

Publication number Publication date
FI874727A0 (en) 1987-10-27
JPS63159319A (en) 1988-07-02
JPH0543684B2 (en) 1993-07-02
RU1836079C (en) 1993-08-23
HU197987B (en) 1989-07-28
IL84312A (en) 1991-11-21
LV10051A (en) 1994-05-10
DK569687A (en) 1988-05-01
EP0265812A1 (en) 1988-05-04
KR900003491B1 (en) 1990-05-21
AU598602B2 (en) 1990-06-28
KR880004814A (en) 1988-06-27
DK569687D0 (en) 1987-10-30
GR3000708T3 (en) 1991-10-10
ZA878183B (en) 1988-05-02
HUT44932A (en) 1988-05-30
PT86032B (en) 1990-08-31
NO873860L (en) 1988-05-02
IL84312A0 (en) 1988-03-31
ES2017982B3 (en) 1991-03-16
DD262582A5 (en) 1988-12-07
FI87140C (en) 1992-12-10
PT86032A (en) 1987-11-01
MX8958A (en) 1993-12-01
GEP19971025B (en) 1997-04-06
UA11075A (en) 1996-12-25
AU8052987A (en) 1988-05-05
NO873860D0 (en) 1987-09-15
LV10051B (en) 1995-06-20
DK169308B1 (en) 1994-10-10
DE3764235D1 (en) 1990-09-13
IN168119B (en) 1991-02-09
CA1314231C (en) 1993-03-09
FI87140B (en) 1992-08-31
EP0265812B1 (en) 1990-08-08
FI874727A (en) 1988-05-01
ATE55250T1 (en) 1990-08-15
EG18333A (en) 1993-12-30

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