YU17503A - Receptor oblasti (ii) edb-fibronektina - Google Patents

Receptor oblasti (ii) edb-fibronektina

Info

Publication number
YU17503A
YU17503A YU17503A YUP17503A YU17503A YU 17503 A YU17503 A YU 17503A YU 17503 A YU17503 A YU 17503A YU P17503 A YUP17503 A YU P17503A YU 17503 A YU17503 A YU 17503A
Authority
YU
Yugoslavia
Prior art keywords
receptor
edb
fibronectin domain
domain
edb fibronectin
Prior art date
Application number
YU17503A
Other languages
English (en)
Inventor
Alexander Redlitz
Marcus Koppitz
Ursula Egner
Inke Paul Bahr
Original Assignee
Schering Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10045803A external-priority patent/DE10045803A1/de
Priority claimed from DE2001123133 external-priority patent/DE10123133A1/de
Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft
Publication of YU17503A publication Critical patent/YU17503A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]

Abstract

Pronalazak se odnosi na jedan protein, koji se specifično vezuje za oblasti EDB-fibronektina, postupak za prikazivanje (screening) jedinjenja, koja se sama vezuju za jedan receptor oblasti EDb-fibronektina ili za oblast EDb-fibronektina, kao i primenu tog proteina.[The invention relates to a protein, which binds specifically to the EDb-fibronectin domain, a method for screening compounds which bind to a receptor in the EDb-fibronectin-domain or to the EDb-fibronectin-domain itself, in addition to the use of said protein.
YU17503A 2000-09-07 2001-08-30 Receptor oblasti (ii) edb-fibronektina YU17503A (sh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10045803A DE10045803A1 (de) 2000-09-07 2000-09-07 Rezeptor der EDb Fibronektin-Domäne
DE2001123133 DE10123133A1 (de) 2001-05-02 2001-05-02 Rezeptor der ED¶b¶-Fibronektin-Domäne (II)

Publications (1)

Publication Number Publication Date
YU17503A true YU17503A (sh) 2006-05-25

Family

ID=26007070

Family Applications (1)

Application Number Title Priority Date Filing Date
YU17503A YU17503A (sh) 2000-09-07 2001-08-30 Receptor oblasti (ii) edb-fibronektina

Country Status (24)

Country Link
US (3) US20020197700A1 (sh)
EP (1) EP1381629B1 (sh)
JP (1) JP2004529848A (sh)
KR (1) KR20030045056A (sh)
CN (1) CN1246333C (sh)
AT (1) ATE407951T1 (sh)
AU (1) AU1218202A (sh)
BG (1) BG107614A (sh)
BR (1) BR0113737A (sh)
CA (1) CA2421783A1 (sh)
DE (1) DE50114321D1 (sh)
EE (1) EE200300092A (sh)
ES (1) ES2312478T3 (sh)
HK (1) HK1064683A1 (sh)
HR (1) HRP20030263A2 (sh)
HU (1) HUP0300935A3 (sh)
IL (1) IL154778A0 (sh)
NO (1) NO20031033L (sh)
NZ (1) NZ524342A (sh)
PL (1) PL364358A1 (sh)
RU (1) RU2280254C2 (sh)
SK (1) SK2882003A3 (sh)
WO (1) WO2002020563A2 (sh)
YU (1) YU17503A (sh)

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WO2001062800A1 (en) 2000-02-24 2001-08-30 Eidgenössische Technische Hochschule Zürich Antibody specific for the ed-b domain of fibronectin, conjugates comprising said antibody, and their use for the detection and treatment of angiogenesis
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BRPI0520677A2 (pt) 2005-11-09 2009-05-19 Bayer Schering Pharma Ag identificação e caracterização de anticorpos de função de bloqueio anti-ed-b-fibronectina
EP1892248A1 (en) * 2006-08-21 2008-02-27 Eidgenössische Technische Hochschule Zürich Specific and high affinity binding proteins comprising modified SH3 domains of FYN kinase
KR101515243B1 (ko) 2007-04-02 2015-04-24 필로겐 에스.피.에이. 종양 전이암의 신생혈관과 관련된 피브리노겐의 ｅｄ―ａ 항원
US10202442B2 (en) 2007-07-25 2019-02-12 Philogen S.P.A. Antigen associated with lung cancers and lymphomas
RU2486198C2 (ru) * 2007-10-30 2013-06-27 Филоджен С.П.А. Антиген, ассоциированный с ревматоидным артритом
ATE548052T1 (de) * 2008-01-17 2012-03-15 Philogen Spa Kombination aus einem anti-edb-fibronectin- antikörper-il-2-fusionsprotein und einem b-zellen bindenden molekül, b-zellen-vorläufern und/oder deren krebserregendem gegenspieler
US8679488B2 (en) 2009-08-05 2014-03-25 Philogen S.P.A. Targeting of bone marrow neovasculature
SI2903629T1 (sl) 2012-10-03 2019-09-30 Philogen S.P.A. Konjugat protitelesa za uporabo pri zdravljenju vnetnih črevesnih bolezni
EP3689903A4 (en) * 2017-09-30 2022-01-12 Hefei Lifeon Pharmaceutical Co. Ltd. FIBRONECTIN B DOMAIN BINDING PROTEIN

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Also Published As

Publication number Publication date
SK2882003A3 (en) 2003-08-05
CN1246333C (zh) 2006-03-22
JP2004529848A (ja) 2004-09-30
WO2002020563A2 (de) 2002-03-14
HUP0300935A2 (hu) 2003-12-29
RU2280254C2 (ru) 2006-07-20
ES2312478T3 (es) 2009-03-01
ATE407951T1 (de) 2008-09-15
PL364358A1 (en) 2004-12-13
US20050221434A1 (en) 2005-10-06
RU2003109431A (ru) 2005-01-20
NO20031033L (no) 2003-05-07
DE50114321D1 (de) 2008-10-23
US20050089941A1 (en) 2005-04-28
HK1064683A1 (en) 2005-02-04
EP1381629B1 (de) 2008-09-10
HRP20030263A2 (en) 2005-10-31
EE200300092A (et) 2005-06-15
EP1381629A2 (de) 2004-01-21
AU1218202A (en) 2002-03-22
IL154778A0 (en) 2003-10-31
NZ524342A (en) 2005-09-30
NO20031033D0 (no) 2003-03-06
HUP0300935A3 (en) 2005-09-28
KR20030045056A (ko) 2003-06-09
US20020197700A1 (en) 2002-12-26
WO2002020563A3 (de) 2003-10-09
CA2421783A1 (en) 2002-03-14
BG107614A (bg) 2003-12-31
BR0113737A (pt) 2004-02-25
CN1487953A (zh) 2004-04-07

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