YU155791A - Antiproliferativna supstituisana triciklična jedinjenja - Google Patents

Antiproliferativna supstituisana triciklična jedinjenja

Info

Publication number
YU155791A
YU155791A YU155791A YU155791A YU155791A YU 155791 A YU155791 A YU 155791A YU 155791 A YU155791 A YU 155791A YU 155791 A YU155791 A YU 155791A YU 155791 A YU155791 A YU 155791A
Authority
YU
Yugoslavia
Prior art keywords
tricyclic compounds
substituted tricyclic
compounds
prevention
prevent
Prior art date
Application number
YU155791A
Other languages
English (en)
Inventor
S.H. Reich
M.A.M. Fuhry
Original Assignee
Agouron Pharmaceuticals Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agouron Pharmaceuticals Inc. filed Critical Agouron Pharmaceuticals Inc.
Priority to HR920519A priority Critical patent/HRP920519A2/xx
Publication of YU155791A publication Critical patent/YU155791A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Ovaj pronalazak odnosi se na izvesna supstiuisana triciklična jedinjenja koja sprečavaju sintez ("TS") enzima timidilata, farmaceutske preparate koji sadrže ova triciklična jedinjenja, i primenu ovih jedinjenja na sprečavanje TS, uključujući sve efekte koji potiču od sprečavanja TS. Efekti koji potiču iz sprečavanja TS obuhvataju sprečavanje rasta i profiliraciju ćelija viših organizama i mikroorganizama, takvih kao kvasac i gljive. Takvi efekti obuhvataju antitumornu aktivnost. Postupci za dobijanje supstituisanih tricikličnih jedinjenja pronalaska takodje su opisani.
YU155791A 1990-09-25 1991-09-23 Antiproliferativna supstituisana triciklična jedinjenja YU155791A (sh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
HR920519A HRP920519A2 (en) 1990-09-25 1992-09-27 Antiproliferative substituted tricyclic compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US58766690A 1990-09-25 1990-09-25

Publications (1)

Publication Number Publication Date
YU155791A true YU155791A (sh) 1994-01-20

Family

ID=24350713

Family Applications (1)

Application Number Title Priority Date Filing Date
YU155791A YU155791A (sh) 1990-09-25 1991-09-23 Antiproliferativna supstituisana triciklična jedinjenja

Country Status (10)

Country Link
EP (1) EP0550589A1 (sh)
JP (1) JPH06503814A (sh)
CN (1) CN1062908A (sh)
AU (1) AU8628791A (sh)
CA (1) CA2091690A1 (sh)
IL (1) IL99551A0 (sh)
MX (1) MX9101228A (sh)
WO (1) WO1992005173A1 (sh)
YU (1) YU155791A (sh)
ZA (1) ZA917613B (sh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994003439A1 (en) * 1992-07-29 1994-02-17 Agouron Pharmaceuticals, Inc. Antiproliferative tricyclic compounds
GB9223352D0 (en) * 1992-11-06 1992-12-23 Ici Plc Tricyclic compounds
GB9408936D0 (en) * 1994-05-05 1994-06-22 Cancer Res Inst Anti-cancer compounds
US7524635B2 (en) 2003-04-17 2009-04-28 Biosite Incorporated Methods and compositions for measuring natriuretic peptides and uses thereof
TW200719899A (en) * 2005-04-14 2007-06-01 Hoffmann La Roche Tricyclic azole derivatives, their manufacture and use as pharmaceutical agents
KR20080044840A (ko) 2005-07-15 2008-05-21 에이엠알 테크놀로지, 인크. 아릴- 및 헤테로아릴-치환된 테트라히드로벤자제핀, 및노르에피네프린, 도파민 및 세로토닌의 재흡수를 차단하기위한 용도
BRPI0811200A8 (pt) 2007-05-10 2015-09-22 Bristol Myers Squibb Co Tetra-hidrobenzapinas arilóxi- e heteroarilóxi-substituídas e uso das mesmas para bloquear percepção de norepinefrina, dopamina, e serotonina
GB201005511D0 (en) * 2010-03-31 2010-05-19 Takeda Pharmaceutical Compounds and their use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0365763A1 (en) * 1988-09-30 1990-05-02 Agouron Pharmaceuticals, Inc. Antiproliferative cyclic compounds

Also Published As

Publication number Publication date
MX9101228A (es) 1992-05-04
EP0550589A1 (en) 1993-07-14
CN1062908A (zh) 1992-07-22
IL99551A0 (en) 1992-08-18
ZA917613B (en) 1992-08-26
CA2091690A1 (en) 1992-03-26
JPH06503814A (ja) 1994-04-28
WO1992005173A1 (en) 1992-04-02
AU8628791A (en) 1992-04-15

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