WO2023137602A1 - Injector - Google Patents

Injector Download PDF

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Publication number
WO2023137602A1
WO2023137602A1 PCT/CN2022/072622 CN2022072622W WO2023137602A1 WO 2023137602 A1 WO2023137602 A1 WO 2023137602A1 CN 2022072622 W CN2022072622 W CN 2022072622W WO 2023137602 A1 WO2023137602 A1 WO 2023137602A1
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WO
WIPO (PCT)
Prior art keywords
guide tube
pushing
housing
tube
glaucoma drainage
Prior art date
Application number
PCT/CN2022/072622
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French (fr)
Chinese (zh)
Inventor
阚敏
汤国兵
王琰
Original Assignee
苏州朗目医疗科技有限公司
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Application filed by 苏州朗目医疗科技有限公司 filed Critical 苏州朗目医疗科技有限公司
Priority to PCT/CN2022/072622 priority Critical patent/WO2023137602A1/en
Publication of WO2023137602A1 publication Critical patent/WO2023137602A1/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery

Definitions

  • the invention relates to the technical field of medical equipment, in particular to a push injector.
  • Glaucoma is a group of diseases characterized by optic disc atrophy and depression, visual field defect and vision loss. Pathological increased intraocular pressure and optic nerve insufficiency are the primary risk factors for its onset. The tolerance of optic nerve to pressure damage is also related to the occurrence and development of glaucoma. Obstacles in any part of the aqueous humor circulation pathway can lead to pathological changes caused by elevated intraocular pressure, but some patients also present with normal intraocular pressure glaucoma. Glaucoma is one of the three major blindness diseases that cause blindness in humans, with an incidence rate of 1% in the general population and 2% after the age of 45. Clinically, glaucoma is divided into three categories: primary, secondary, and congenital according to the etiology, anterior chamber angle, and intraocular pressure tracings.
  • drainage implants are usually implanted inside the eyes of the human body to reconstruct the outflow channel of aqueous humor, thereby reducing intraocular pressure to achieve therapeutic purposes. Drainage implants are usually implanted into the schlemm canal by a doctor by hand. This implantation method has the problems of inaccurate positioning and poor implantation effect.
  • the injectors currently on the market are implanted through the internal route (a part of the injector enters the schlemm tube to implant the drainage implant), which is complicated and depends on the experience of clinicians, and the operation time is relatively long.
  • the invention provides a pusher, which solves the problems of inaccurate positioning and poor implantation effect of glaucoma drainage implants in the prior art.
  • a technical solution adopted by the present invention is to provide a injector for pushing the glaucoma drainage implant into the schlemm tube, including a housing, a guide tube, a pushing mechanism, and a push wire; the guide tube is connected to the housing, and its distal end is used to accommodate the glaucoma drainage implant; Mechanism connection; the pushing mechanism is at least partially exposed to the housing, and is used to provide a pushing force to the pushing wire so that the glaucoma drainage implant is pushed into the schlemm tube along the guide tube, and during the pushing process of the pushing mechanism, the distal end of the guide tube abuts against the outside of the schlemm tube.
  • the pushing mechanism includes a fixed frame and a main gear, an intermediate gear, and a pushing rack mounted on the fixed frame;
  • the main gear is at least partly exposed to the housing to form a knob, the main gear is in transmission connection with the push rack through the intermediate gear, and the front end of the push rack is connected with a fixing block for fixing the push wire.
  • the guide tube includes a curved guide tube at a distal end and a straight guide tube connected to the curved guide tube.
  • the curved guide tube includes a first curved guide tube and a second curved guide tube, and the second curved guide tube is connected to the straight guide tube.
  • an anti-trigger mechanism is provided on the side of the housing, and the anti-trigger mechanism is used to limit the movement of the push rack.
  • the anti-trigger mechanism is a limit pin, and the limit pin passes through the housing and the push rack.
  • the front end of the housing is provided with a guide tube protection sleeve, the guide tube runs through the guide tube protection sleeve, and the tail of the guide tube protection sleeve is installed in the housing.
  • a guide tube fixing sleeve is provided inside the guide tube protective sleeve, the proximal end of the guide tube passes through the guide tube fixing sleeve, and the outer wall of the guide tube is fixedly connected to the guide tube fixing sleeve.
  • the head of the housing is covered with a plurality of anti-slip rubber rings.
  • the housing includes a first housing and a second housing that are detachably connected.
  • the present invention discloses a push injector, which is used to push the glaucoma drainage implant into the schlemm tube, including a housing, a guiding tube, a pushing mechanism, and a pushing wire;
  • the guiding tube is connected to the housing, and its distal end is used to accommodate the glaucoma drainage implant, and the pushing wire is arranged inside the guiding tube;
  • the wire provides a pushing force so that the glaucoma drainage implant is pushed into the schlemm tube along the guide tube, and during the pushing process of the pushing mechanism, the distal end of the guide tube abuts against the outside of the schlemm tube.
  • the injector in the present application has good pushing effect, high precision and is convenient for operators to use.
  • Fig. 1 is the use schematic diagram of a kind of injector according to the present invention
  • Fig. 2 is a schematic diagram of the abutment process between the guide tube in the injector and the schlemm tube of the human eye according to the present invention
  • Fig. 3 is the overall schematic diagram of a kind of injector according to the present invention.
  • Fig. 4 is an exploded schematic view of a injector according to the present invention.
  • Fig. 5 is a schematic diagram of a first embodiment of a guide tube in a syringe according to the present invention
  • Fig. 6 is an overall schematic diagram of a second embodiment of a guide tube in a syringe according to the present invention.
  • Fig. 7 is an exploded schematic diagram of a second embodiment of a guide tube in a syringe according to the present invention.
  • Fig. 8 is an overall schematic diagram of a pushing mechanism in a syringe according to the present invention.
  • Fig. 9 is an exploded schematic diagram of a pushing mechanism in a syringe according to the present invention.
  • Fig. 10 is a schematic diagram of a guide tube protective sleeve and a guide tube fixing sleeve in a syringe according to the present invention
  • Fig. 11 is a schematic diagram of a second housing in a syringe according to the present invention.
  • the injector is used to push the glaucoma drainage implant 5 into the schlemm canal, and the glaucoma drainage implant 5 can rebuild the outflow channel of aqueous humor, thereby reducing intraocular pressure to achieve therapeutic purposes.
  • a glaucoma drainage implant 5 Before the injection of the glaucoma drainage implant 5 , an operation incision is first made on the schlemm tube, so that two nozzles will be produced on the schlemm tube. Then, the distal end of the guide tube 2 of the injector is abutted against the outside of the schlemm tube, that is, the distal end of the guide tube 2 is kept coaxially flush with the mouth of the schlemm tube, but does not enter the schlemm tube; thereby facilitating the smooth introduction of the glaucoma drainage implant 5 into the schlemm tube; a glaucoma drainage implant 5 can be implanted on both sides of the surgical incision.
  • This method is not only suitable for the operation of open-angle glaucoma, but also can be used for the operation of angle-closure glaucoma.
  • the injector is implanted externally, and the guide tube 2 of the injector does not enter the schlemm tube of the human eye.
  • the operation process is simple, the operation is convenient, the operation time is short, and the patient's eye pain is reduced.
  • the existing bolus is implanted through the internal route, and the guide tube of the bolus will enter the schlemm canal of the human eye.
  • the operation process is complicated and difficult, and the patient will also cause greater pain in the eye during the operation.
  • distal end refers to the end close to the eyeball
  • proximal end refers to the end close to the operator's hand
  • the injector comprises a housing 1, a guide tube 2, a pushing mechanism 3, and a pushing wire 4.
  • the guide tube 2 is connected with the housing 1, and its distal end is used to accommodate the glaucoma drainage implant 5, and the push wire 4 is arranged inside the guide tube 2, and the distal end of the push wire 4 abuts against the glaucoma drainage implant 5, that is, the distal end of the push wire 4 can push the glaucoma drainage implant 5 to expose the guide tube 2, thereby entering the schlemm tube of the human eye.
  • the proximal end of the push wire 4 exposes the proximal end of the guide tube 2 and is connected to the push mechanism 3 inside the housing 1.
  • the push mechanism 3 provides a thrust to the push wire 4, so that the push wire can push the glaucoma drainage implant 5 to expose the guide tube 2, and can also return to the initial position after the push is completed.
  • the pushing mechanism 3 is at least partly exposed from the housing 1 , and is used to provide pushing force to the pushing wire 4 so that the glaucoma drainage implant 5 is pushed into the schlemm canal along the guide tube.
  • the distal end of the guide tube 2 abuts against the outside of the schlemm tube.
  • the far end of the push wire 4 can only push the glaucoma drainage implant 5 out of the guide tube 2 to complete the one-way push; it cannot drive the glaucoma drainage implant 5 back into the guide tube 2.
  • the push wire 4 returns to the inside of the housing 1, the glaucoma drainage implant 5 is in a static state and does not move.
  • the guide tube 2 includes a curved guide tube 21 at the distal end and a straight guide tube 22 connected to the curved guide tube 21 .
  • the curved guide tube 21 is matched with the glaucoma drainage implant 5 and the schlemm tube of the human eye, thereby facilitating the introduction of the glaucoma drainage implant 5
  • the straight guide tube 22 is connected with the housing 1 .
  • the curved guide tube 21 includes a first curved guide tube 211 and a second curved guide tube 212 , and the second curved guide tube 212 is connected to the straight guide tube 22 .
  • the glaucoma drainage implants 5 which are accommodated in the first curved guide tube 211.
  • the glaucoma drainage implant 5 abuts against the distal end of the push wire 4; the push wire 4 is partly accommodated inside the guide tube 2, and the overall shape of the push wire 4 is consistent with the overall shape of the guide tube 2, which is convenient for pushing.
  • the guide tube 2 has good biocompatibility, and its material can be stainless steel, such as 2Cr13, 1Cr13, 1Cr18Ni9, SUS304(L), SUS316(L), SUS430, etc.; it can also be titanium alloy, such as TC4, etc.; it can also be pure titanium, tungsten steel, platinum, platinum-iridium alloy, polymer materials, and modified engineering plastics.
  • stainless steel such as 2Cr13, 1Cr13, 1Cr18Ni9, SUS304(L), SUS316(L), SUS430, etc.
  • titanium alloy such as TC4, etc.
  • it can also be pure titanium, tungsten steel, platinum, platinum-iridium alloy, polymer materials, and modified engineering plastics.
  • the measurement result of the diameter of the Schlemm tube of the human eye is 0.39mm-0.63mm, and the average value is (0.50 ⁇ 0.07)mm.
  • the shape, size and size of the glaucoma drainage implant 5 are customized according to the Schlemm canal of the human eye, and the diameter of the guide tube 2 matches the glaucoma drainage implant 5 .
  • the diameter of the glaucoma drainage implant 5 ranges from 0.1mm to 0.5mm
  • the length of the glaucoma drainage implant 5 ranges from 1mm to 5mm
  • the curvature range of the glaucoma drainage implant 5 ranges from R4mm to R10mm.
  • the diameter of the inner wall of the guide tube 2 ranges from 0.1 mm to 0.5 mm, and the diameter of the outer wall of the guide tube 2 ranges from 0.1 mm to 1 mm.
  • the curvature of the curved guide tube 21 matches the curvature of the schlemm canal, which facilitates the operator's hands to introduce the glaucoma drainage implant 5 into the schlemm canal at a more comfortable angle.
  • the curvature range of the curved guide tube 21 R4mm-R10mm; in FIG. 6, the curvature range of the first curved guide tube 211: R4mm-R10mm, and the curvature range of the second curved guide tube 212: R3mm-R8mm.
  • the pushing mechanism 3 includes a fixed frame 31 and a main gear 32 , an intermediate gear 33 , and a pushing rack 34 installed on the fixed frame 31 .
  • a first fixed rod 301 and a second fixed rod 302 are arranged on the fixed frame 31 , the main gear 32 can rotate around the first fixed rod 301 , and the intermediate gear 33 can rotate around the second fixed rod 302 .
  • the pushing rack 34 meshes with the intermediate gear 33 and moves forward and backward along the fixed frame 31 .
  • the main gear 32 is at least partly exposed to the housing 1 to form a knob.
  • the main gear 32 can push the glaucoma drainage implant 5 forward in the guide tube 2, and when the main gear 32 is retreating, the glaucoma drainage implant 5 is in a static state.
  • the knob part of the main gear 32 exposed from the housing 1 may be provided with protrusions or depressions, so that the operator can feel the pushing distance of the glaucoma drainage implant 5 during the pushing process.
  • the protrusions or depressions are regularly distributed, which can effectively feedback the travel tactile sensation of the main gear 32; the knob part can also be wrapped with silica gel.
  • the main gear 32 is in transmission connection with the push rack 34 through the intermediate gear 33, and the front end of the push rack 34 is connected with a fixing block 35 for fixing the push wire 4.
  • the proximal end of the push wire 4 passes through the fixed block 35 and bends downwards, and finally is fixedly connected with the fixed block 35.
  • the fixed block 35 is connected with the front end of the push rack 34 by plugging, and a plug post 351 is arranged on the side of the front end of the push rack 34 near the fixed block 35.
  • the working principle of the push mechanism 3 is: after the main gear 32 is moved, the intermediate gear 33 rotates and then drives the push rack 34 to move back and forth, the fixed block 35 moves back and forth synchronously, and then drives the push wire 4 to move back and forth in the guide tube 2 (the guide tube 2 remains stationary); when the push wire 4 moves outward, the glaucoma drainage implant 5 can be pushed out of the guide tube 2.
  • the transmission ratio of the main gear 32 and the intermediate gear 33 is 0.2-5.
  • the transmission ratio of the main gear 32 and the intermediate gear 33 is greater than 1, that is, the rotation speed of the main gear 32 is faster than that of the intermediate gear 33, so it is decelerated.
  • the purpose is to ensure that the glaucoma drainage implant 5 slowly enters the schlemm tube from the guide tube 2 when the operator performs surgery, and also avoids surgical risks caused by some misoperations.
  • the material of the fixing frame 31 may be ABS, POM, PEEK, PVC, PET, nylon, polymer material, modified engineering plastic, zinc alloy, aluminum alloy, magnesium aluminum alloy, stainless steel, copper, iron, etc.
  • the diameter of the push wire 4 is 0.1mm-0.5mm, and the push wire can be made of SUS300 series/SUS400 series stainless steel.
  • an anti-trigger mechanism is provided on the side of the housing 1, and the anti-trigger mechanism is used to limit the movement of the push rack 34, so as to prevent the injector from being triggered due to no action before official use, causing the injector to fail. After removing the structure, it indicates that the injector has been used and cannot be restored, and a reminder is given to the operator.
  • the anti-trigger mechanism is a limit pin 6 , and the limit pin 6 passes through the housing 1 and the push rack 34 .
  • One end of the limit latch 6 is provided with a pinch plate 61, and the setting of the pinch plate 61 facilitates the extraction of the limit latch 6.
  • the anti-trigger mechanism can also be a round rod, a square rod, a metal wire or a string, etc.
  • the front end of the casing 1 is provided with a guide tube protective sleeve 7
  • the guide tube 2 runs through the guide tube protective sleeve 7
  • the tail portion 72 of the guide tube protective sleeve 7 is installed in the housing 1 .
  • the head 71 of the guide tube protective cover 7 is tapered gradually, and colloid can be used between the tip of the head 71 of the guide tube protective cover 7 and the guide tube 2 to prevent the guide tube 2 from shaking.
  • the tail portion 72 of the guide tube protection sleeve 7 is cylindrical, and a limiting block 73 is arranged on the tail portion 72 of the guide tube protection sleeve 7 .
  • the housing 1 includes a first housing 101 and a second housing 102 that are detachably connected, and the detachable connection includes buckling, clamping, threaded connection and the like.
  • the front end of the second housing 102 is provided with a mounting platform 105
  • the mounting platform 105 is provided with a mounting groove 106 for placing the tail portion 72 of the guide tube protective sleeve 7 .
  • the groove wall of the mounting groove 106 is also provided with a corresponding limiting groove 107 that is compatible with the limiting block 73 ;
  • the inside of the guide tube protective sleeve 7 is provided with a guide tube fixing sleeve 8, the proximal end of the guide tube 2 runs through the guide tube fixing sleeve 8, and the outer wall of the guide tube 2 is fixedly connected to the guide fixing sleeve 8, and the fixed connection can be fixed by colloid.
  • the head 81 of the guide tube fixing sleeve 8 is inserted into the tail portion 72 of the guide tube protective sleeve 7, and the head 81 of the guide tube fixing sleeve 8 and the tail portion 72 of the guide tube protective sleeve 7 are fixed by colloid;
  • a plurality of anti-slip rubber rings 104 are sheathed on the head of the housing 1 , and rubber ring grooves 103 for accommodating the anti-slip rubber rings 104 are also provided on the first housing 101 and the second housing 102 .
  • the anti-slip rubber ring 104 is convenient for the operator to grasp, stimulates the operator's senses, and also plays a role in increasing the appearance.
  • the second housing 102 has a flat bottom surface 104 inside, and the flat bottom surface 104 is used to fix the fixing bracket 31 of the pushing mechanism 3 , and the fixing bracket 31 can be glued or ultrasonically welded on the flat bottom surface 104 .
  • a plurality of reinforcing ribs 108 are provided inside the second housing 102, and the reinforcing ribs 108 are used to increase the strength of the housing and prevent easy damage.
  • the position of the first housing 101 close to the main gear 32 is provided with an indicator mark 9, which indicates the pushing direction.
  • the indication mark 9 can be a protrusion, a depression, a silk screen or a sticker.
  • the shape of the housing 1 is large in the middle and small at the two ends, or large at both ends and small at the middle, or a straight rod type, which is suitable for one-handed operation.
  • the diameter of the housing 1 ranges from 5 mm to 20 mm, and the length ranges from 5 cm to 20 cm.
  • the material of the housing 1 can be ABS, POM, PEEK, PVC, PET, nylon, polymer materials, modified engineering plastics, zinc alloy, aluminum alloy, magnesium aluminum alloy, stainless steel, copper, iron, etc.
  • the sterilization methods of the injector may include: gas sterilization (ethylene oxide, formaldehyde, ozone), radiation sterilization (microwave, ultraviolet (UV), X-ray and ⁇ -ray, etc.).
  • the present invention discloses a push injector, which is used to push the glaucoma drainage implant into the schlemm tube, including a housing, a guide tube, a pushing mechanism, and a pusher wire; the guide tube is connected to the housing, and its distal end is used to accommodate the glaucoma drainage implant, and the pusher wire is arranged inside the guide tube; The glaucoma drainage implant is pushed into the schlemm tube along the guide tube, and the distal end of the guide tube abuts against the outside of the schlemm tube during the pushing process of the pushing mechanism.
  • the injector in the present application has good pushing effect, high precision and is convenient for operators to use.

Abstract

An injector, used for pushing a glaucoma drainage implant (5) into a schlemm canal, comprising a housing (1), a guide canal (2), a pushing mechanism (3), and a pushing wire (4). The guide canal (2) is connected to the housing (1), a distal end of the guide canal is used for accommodating the glaucoma drainage implant (5); the pushing wire (4) is provided in the guide canal (2); a distal end of the pushing wire (4) is abutted against the glaucoma drainage implant (5); a proximal end of the pushing wire (4) exposes a proximal end of the guide canal (2), and is connected to the pushing mechanism (3) in the housing (1); at least part of the pushing mechanism (3) is exposed to the housing (1), and is used for providing pushing force for the pushing wire (4), such that the glaucoma drainage implant (5) is pushed into the schlemm canal along the guide canal (2); and in the pushing process of the pushing mechanism (3), the distal end of the guide canal (2) is abutted against the exterior of the schlemm canal.

Description

一种推注器a syringe 技术领域technical field
本发明涉及医用器材技术领域，尤其涉及一种推注器。The invention relates to the technical field of medical equipment, in particular to a push injector.
背景技术Background technique
青光眼(glaucoma)是一组以视***萎缩及凹陷、视野缺损及视力下降为共同特征的疾病，病理性眼压增高、视神经供血不足是其发病的原发危险因素，视神经对压力损害的耐受性也与青光眼的发生和发展有关。在房水循环途径中任何一环发生阻碍，均可导致眼压升高而引起的病理改变，但也有部分患者呈现正常眼压青光眼。青光眼是导致人类失明的三大致盲眼病之一，总人群发病率为1％，45岁以后为2％。临床上根据病因、房角、眼压描记等情况将青光眼分为原发性、继发性和先天性三大类。Glaucoma is a group of diseases characterized by optic disc atrophy and depression, visual field defect and vision loss. Pathological increased intraocular pressure and optic nerve insufficiency are the primary risk factors for its onset. The tolerance of optic nerve to pressure damage is also related to the occurrence and development of glaucoma. Obstacles in any part of the aqueous humor circulation pathway can lead to pathological changes caused by elevated intraocular pressure, but some patients also present with normal intraocular pressure glaucoma. Glaucoma is one of the three major blindness diseases that cause blindness in humans, with an incidence rate of 1% in the general population and 2% after the age of 45. Clinically, glaucoma is divided into three categories: primary, secondary, and congenital according to the etiology, anterior chamber angle, and intraocular pressure tracings.
现有技术中，通常采用植入引流植入物在人体的眼睛内部，重建房水流出通道，从而降低眼压以达到治疗目的。引流植入物通常是通过医生徒手将引流植入物植入至schlemm管中，这种植入方式存在定位不精准，植入效果差的问题。In the prior art, drainage implants are usually implanted inside the eyes of the human body to reconstruct the outflow channel of aqueous humor, thereby reducing intraocular pressure to achieve therapeutic purposes. Drainage implants are usually implanted into the schlemm canal by a doctor by hand. This implantation method has the problems of inaccurate positioning and poor implantation effect.
目前市面上的推注器采用内路植入(推注器的一部分进入schlemm管内植入引流植入物)，手术复杂，依赖于临床医生的经验积累，手术时间较长。The injectors currently on the market are implanted through the internal route (a part of the injector enters the schlemm tube to implant the drainage implant), which is complicated and depends on the experience of clinicians, and the operation time is relatively long.
发明内容Contents of the invention
本发明提供一种推注器，解决现有技术中青光眼引流植入物植入方式定位不精准，植入效果差的问题。The invention provides a pusher, which solves the problems of inaccurate positioning and poor implantation effect of glaucoma drainage implants in the prior art.
为解决上述技术问题，本发明采用的一个技术方案是提供一种推注器，用于将青光眼引流植入物推送至schlemm管中，包括壳体、导 向管、推送机构、推丝；所述导向管与所述壳体连接，其远端用于容纳青光眼引流植入物，所述推丝设置在所述导向管的内部，所述推丝的远端与青光眼引流植入物抵接，所述推丝的近端露出所述导向管的近端、与所述壳体内部的所述推送机构连接；所述推送机构至少部分外露于所述壳体，用于向所述推丝提供推送力、以使青光眼引流植入物沿所述导向管推送至schlemm管内，在所述推送机构推送过程中，所述导向管的远端与schlemm管的外部抵接。In order to solve the above-mentioned technical problems, a technical solution adopted by the present invention is to provide a injector for pushing the glaucoma drainage implant into the schlemm tube, including a housing, a guide tube, a pushing mechanism, and a push wire; the guide tube is connected to the housing, and its distal end is used to accommodate the glaucoma drainage implant; Mechanism connection; the pushing mechanism is at least partially exposed to the housing, and is used to provide a pushing force to the pushing wire so that the glaucoma drainage implant is pushed into the schlemm tube along the guide tube, and during the pushing process of the pushing mechanism, the distal end of the guide tube abuts against the outside of the schlemm tube.
优选的，所述推送机构包括固定架以及安装在所述固定架上的主齿轮、中间齿轮、推送齿条；Preferably, the pushing mechanism includes a fixed frame and a main gear, an intermediate gear, and a pushing rack mounted on the fixed frame;
所述主齿轮至少部分外露于所述壳体以形成旋钮，所述主齿轮通过所述中间齿轮与所述推送齿条传动连接，所述推送齿条的前端连接有用于固定所述推丝的固定块。The main gear is at least partly exposed to the housing to form a knob, the main gear is in transmission connection with the push rack through the intermediate gear, and the front end of the push rack is connected with a fixing block for fixing the push wire.
优选的，所述导向管包括远端的弯曲导向管和连接所述弯曲导向管的直线导向管。Preferably, the guide tube includes a curved guide tube at a distal end and a straight guide tube connected to the curved guide tube.
优选的，所述弯曲导向管包括第一弯曲导向管和第二弯曲导向管，所述第二弯曲导向管连接所述直线导向管。Preferably, the curved guide tube includes a first curved guide tube and a second curved guide tube, and the second curved guide tube is connected to the straight guide tube.
优选的，所述壳体的侧面设置有防触发机构，所述防触发机构用于限制所述推送齿条移动。Preferably, an anti-trigger mechanism is provided on the side of the housing, and the anti-trigger mechanism is used to limit the movement of the push rack.
优选的，所述防触发机构为限位插销，所述限位插销贯穿所述壳体和所述推送齿条。Preferably, the anti-trigger mechanism is a limit pin, and the limit pin passes through the housing and the push rack.
优选的，所述壳体的前端设置有导向管保护套，所述导向管贯穿所述导向管保护套，所述导向管保护套的尾部安装在所述壳体内。Preferably, the front end of the housing is provided with a guide tube protection sleeve, the guide tube runs through the guide tube protection sleeve, and the tail of the guide tube protection sleeve is installed in the housing.
优选的，所述导向管保护套的内部设置有导向管固定套，所述导向管的近端贯穿所述导向管固定套，并且所述导向管的外壁与所述导向固定套固定连接。Preferably, a guide tube fixing sleeve is provided inside the guide tube protective sleeve, the proximal end of the guide tube passes through the guide tube fixing sleeve, and the outer wall of the guide tube is fixedly connected to the guide tube fixing sleeve.
优选的，所述壳体的头部套设有多个防滑胶圈。Preferably, the head of the housing is covered with a plurality of anti-slip rubber rings.
优选的，所述壳体包括可拆卸连接的第一壳体和第二壳体。Preferably, the housing includes a first housing and a second housing that are detachably connected.
本发明的有益效果是：本发明公开了一种推注器，用于将青光眼引流植入物推送至schlemm管中，包括壳体、导向管、推送机构、推 丝；导向管与壳体连接，其远端用于容纳青光眼引流植入物，推丝设置在导向管的内部，推丝的远端与青光眼引流植入物抵接，推丝的近端露出导向管的近端、与壳体内部的推送机构连接；推送机构至少部分外露于壳体，用于向推丝提供推送力、以使青光眼引流植入物沿导向管推送至schlemm管内，在推送机构推送过程中，导向管的远端与schlemm管的外部抵接。本申请中的推注器推送效果好，精确度高，并且方便操作者使用。The beneficial effects of the present invention are: the present invention discloses a push injector, which is used to push the glaucoma drainage implant into the schlemm tube, including a housing, a guiding tube, a pushing mechanism, and a pushing wire; the guiding tube is connected to the housing, and its distal end is used to accommodate the glaucoma drainage implant, and the pushing wire is arranged inside the guiding tube; The wire provides a pushing force so that the glaucoma drainage implant is pushed into the schlemm tube along the guide tube, and during the pushing process of the pushing mechanism, the distal end of the guide tube abuts against the outside of the schlemm tube. The injector in the present application has good pushing effect, high precision and is convenient for operators to use.
附图说明Description of drawings
图1是根据本发明一种推注器的使用示意图；Fig. 1 is the use schematic diagram of a kind of injector according to the present invention;
图2是根据本发明一种推注器中导向管与人眼的schlemm管的抵接过程示意图；Fig. 2 is a schematic diagram of the abutment process between the guide tube in the injector and the schlemm tube of the human eye according to the present invention;
图3是根据本发明一种推注器的整体示意图；Fig. 3 is the overall schematic diagram of a kind of injector according to the present invention;
图4是根据本发明一种推注器的分解示意图；Fig. 4 is an exploded schematic view of a injector according to the present invention;
图5是根据本发明一种推注器中导向管的第一个实施例示意图；Fig. 5 is a schematic diagram of a first embodiment of a guide tube in a syringe according to the present invention;
图6是根据本发明一种推注器中导向管的第二个实施例的整体示意图；Fig. 6 is an overall schematic diagram of a second embodiment of a guide tube in a syringe according to the present invention;
图7是根据本发明一种推注器中导向管的第二个实施例的分解示意图；Fig. 7 is an exploded schematic diagram of a second embodiment of a guide tube in a syringe according to the present invention;
图8是根据本发明一种推注器中推送机构的整体示意图；Fig. 8 is an overall schematic diagram of a pushing mechanism in a syringe according to the present invention;
图9是根据本发明一种推注器中推送机构的分解示意图；Fig. 9 is an exploded schematic diagram of a pushing mechanism in a syringe according to the present invention;
图10是根据本发明一种推注器中导向管保护套和导向管固定套的示意图；Fig. 10 is a schematic diagram of a guide tube protective sleeve and a guide tube fixing sleeve in a syringe according to the present invention;
图11是根据本发明一种推注器中第二壳体的示意图。Fig. 11 is a schematic diagram of a second housing in a syringe according to the present invention.
具体实施方式Detailed ways
为了便于理解本发明，下面结合附图和具体实施例，对本发明进行更详细的说明。附图中给出了本发明的较佳的实施例。但是，本发明可以以许多不同的形式来实现，并不限于本说明书所描述的实施 例。相反地，提供这些实施例的目的是使对本发明的公开内容的理解更加透彻全面。In order to facilitate the understanding of the present invention, the present invention will be described in more detail below in conjunction with the accompanying drawings and specific embodiments. Preferred embodiments of the invention are shown in the accompanying drawings. However, the present invention can be implemented in many different forms and is not limited to the embodiments described in this specification. On the contrary, these embodiments are provided to make the understanding of the disclosure of the present invention more thorough and comprehensive.
需要说明的是，除非另有定义，本说明书所使用的所有的技术和科学术语与属于本发明的技术领域的技术人员通常理解的含义相同。在本发明的说明书中所使用的术语只是为了描述具体的实施例的目的，不是用于限制本发明。本说明书所使用的术语“和/或”包括一个或多个相关的所列项目的任意的和所有的组合。It should be noted that, unless otherwise defined, all technical and scientific terms used in this specification have the same meaning as commonly understood by those skilled in the technical field of the present invention. Terms used in the description of the present invention are only for the purpose of describing specific embodiments, and are not used to limit the present invention. The term "and/or" used in this specification includes any and all combinations of one or more of the associated listed items.
如图1和图2所示，推注器用于将青光眼引流植入物5推送至schlemm管中，青光眼引流植入物5能够重建房水流出通道，从而降低眼压以达到治疗目的。As shown in Figures 1 and 2, the injector is used to push the glaucoma drainage implant 5 into the schlemm canal, and the glaucoma drainage implant 5 can rebuild the outflow channel of aqueous humor, thereby reducing intraocular pressure to achieve therapeutic purposes.
青光眼引流植入物5推注前，首先在schlemm管上切开手术切口，这样schlemm管上会产生两个管口。然后将推注器的导向管2的远端与schlemm管的外部抵接，即导向管2的远端与schlemm管的管口保持同轴平齐，但不进入schlemm管内；从而方便将青光眼引流植入物5顺利导入schlemm管内；手术切口的两边可各植入一个青光眼引流植入物5。该方式不仅适用于开角型青光眼的手术，也能用于闭角型青光眼的手术。Before the injection of the glaucoma drainage implant 5 , an operation incision is first made on the schlemm tube, so that two nozzles will be produced on the schlemm tube. Then, the distal end of the guide tube 2 of the injector is abutted against the outside of the schlemm tube, that is, the distal end of the guide tube 2 is kept coaxially flush with the mouth of the schlemm tube, but does not enter the schlemm tube; thereby facilitating the smooth introduction of the glaucoma drainage implant 5 into the schlemm tube; a glaucoma drainage implant 5 can be implanted on both sides of the surgical incision. This method is not only suitable for the operation of open-angle glaucoma, but also can be used for the operation of angle-closure glaucoma.
可以看出，该推注器其采用外路植入，推注器的导向管2并不进入人眼的schlemm管内，手术过程简单，操作方便，手术时间很短，减少了病人的眼部疼痛。现有的推注器采用内路植入，推注器的导向管会进入至人眼的schlemm管内，手术过程复杂，难度较高，病人在手术过程中也会导致眼部产生较大的疼痛感。It can be seen that the injector is implanted externally, and the guide tube 2 of the injector does not enter the schlemm tube of the human eye. The operation process is simple, the operation is convenient, the operation time is short, and the patient's eye pain is reduced. The existing bolus is implanted through the internal route, and the guide tube of the bolus will enter the schlemm canal of the human eye. The operation process is complicated and difficult, and the patient will also cause greater pain in the eye during the operation.
在本申请中，远端是指靠近眼球的一端，近端是指靠近操作者手部的一端。In this application, the distal end refers to the end close to the eyeball, and the proximal end refers to the end close to the operator's hand.
进一步的，结合图3至图7。推注器包括壳体1、导向管2、推送机构3、推丝4。其中，导向管2与壳体1连接，其远端用于容纳青光眼引流植入物5，推丝4设置在导向管2的内部，推丝4的远端与青光眼引流植入物5抵接，即推丝4的远端可以推动青光眼引流植入物5露出导向管2，从而进入人眼的schlemm管内。推丝4的近端 露出导向管2的近端、与壳体1内部的推送机构3连接，该推送机构3向推丝4提供推力，既可以使推丝推动青光眼引流植入物5露出导向管2，也能够在推送完成后，回位至初始位置。Further, refer to FIG. 3 to FIG. 7 . The injector comprises a housing 1, a guide tube 2, a pushing mechanism 3, and a pushing wire 4. Wherein, the guide tube 2 is connected with the housing 1, and its distal end is used to accommodate the glaucoma drainage implant 5, and the push wire 4 is arranged inside the guide tube 2, and the distal end of the push wire 4 abuts against the glaucoma drainage implant 5, that is, the distal end of the push wire 4 can push the glaucoma drainage implant 5 to expose the guide tube 2, thereby entering the schlemm tube of the human eye. The proximal end of the push wire 4 exposes the proximal end of the guide tube 2 and is connected to the push mechanism 3 inside the housing 1. The push mechanism 3 provides a thrust to the push wire 4, so that the push wire can push the glaucoma drainage implant 5 to expose the guide tube 2, and can also return to the initial position after the push is completed.
在图3中，推送机构3至少部分外露于壳体1，用于向推丝4提供推送力、以使青光眼引流植入物5沿导向管推送至schlemm管内。在推送机构3推送过程中，导向管2的远端与schlemm管的外部抵接。In FIG. 3 , the pushing mechanism 3 is at least partly exposed from the housing 1 , and is used to provide pushing force to the pushing wire 4 so that the glaucoma drainage implant 5 is pushed into the schlemm canal along the guide tube. During the pushing process of the pushing mechanism 3, the distal end of the guide tube 2 abuts against the outside of the schlemm tube.
由于青光眼引流植入物5与推丝4的远端之间是抵顶接触，推丝4的远端只能推送青光眼引流植入物5露出导向管2，完成单向推送；而不能带动青光眼引流植入物5重新回位至导向管2内，推丝4在向壳体1内部回位时，青光眼引流植入物5处于静止状态，不发生移动。Since the distal end of the glaucoma drainage implant 5 and the push wire 4 is in contact with each other, the far end of the push wire 4 can only push the glaucoma drainage implant 5 out of the guide tube 2 to complete the one-way push; it cannot drive the glaucoma drainage implant 5 back into the guide tube 2. When the push wire 4 returns to the inside of the housing 1, the glaucoma drainage implant 5 is in a static state and does not move.
进一步的，作为导向管2的一个实施例。在图5中，导向管2包括远端的弯曲导向管21和连接弯曲导向管21的直线导向管22。弯曲导向管21与青光眼引流植入物5以及人眼的schlemm管相匹配，进而方便推出青光眼引流植入物5，直线导向管22与壳体1相连接。Further, as an embodiment of the guide tube 2 . In FIG. 5 , the guide tube 2 includes a curved guide tube 21 at the distal end and a straight guide tube 22 connected to the curved guide tube 21 . The curved guide tube 21 is matched with the glaucoma drainage implant 5 and the schlemm tube of the human eye, thereby facilitating the introduction of the glaucoma drainage implant 5 , and the straight guide tube 22 is connected with the housing 1 .
进一步的，作为导向管2的另一个实施例。在图6和图7中，弯曲导向管21包括第一弯曲导向管211和第二弯曲导向管212，第二弯曲导向管212连接直线导向管22。可以看出，在图7中，青光眼引流植入物5具有两个，容纳在第一弯曲导向管211内，青光眼引流植入物5与推丝4的远端抵接；推丝4部分容纳在导向管2内部，推丝4的整体形状与导向管2的整体形状保持一致，方便推送。Further, as another embodiment of the guide tube 2 . In FIGS. 6 and 7 , the curved guide tube 21 includes a first curved guide tube 211 and a second curved guide tube 212 , and the second curved guide tube 212 is connected to the straight guide tube 22 . It can be seen that in FIG. 7, there are two glaucoma drainage implants 5, which are accommodated in the first curved guide tube 211. The glaucoma drainage implant 5 abuts against the distal end of the push wire 4; the push wire 4 is partly accommodated inside the guide tube 2, and the overall shape of the push wire 4 is consistent with the overall shape of the guide tube 2, which is convenient for pushing.
进一步的，导向管2具有很好的生物相容性，其材料可以是不锈钢，例如2Cr13、1Cr13、1Cr18Ni9、SUS304(L)、SUS316(L)、SUS430等；也可以是钛合金，例如TC4等；还可以是纯钛、钨钢、铂金、铂铱合金、高分子材料、改性工程塑料。Further, the guide tube 2 has good biocompatibility, and its material can be stainless steel, such as 2Cr13, 1Cr13, 1Cr18Ni9, SUS304(L), SUS316(L), SUS430, etc.; it can also be titanium alloy, such as TC4, etc.; it can also be pure titanium, tungsten steel, platinum, platinum-iridium alloy, polymer materials, and modified engineering plastics.
进一步的，人眼的Schlemm管直径测量结果为0.39mm～0.63mm，平均值为(0.50±0.07)mm。青光眼引流植入物5的形状、尺寸和大小是根据人眼的Schlemm管进行定制的，导向管2的直径与青光眼引流植入物5相匹配。Further, the measurement result of the diameter of the Schlemm tube of the human eye is 0.39mm-0.63mm, and the average value is (0.50±0.07)mm. The shape, size and size of the glaucoma drainage implant 5 are customized according to the Schlemm canal of the human eye, and the diameter of the guide tube 2 matches the glaucoma drainage implant 5 .
在本申请中，青光眼引流植入物5的直径范围为0.1mm～0.5mm， 青光眼引流植入物5的长度范围为1mm～5mm；青光眼引流植入物5的曲率范围：R4mm～R10mm。In this application, the diameter of the glaucoma drainage implant 5 ranges from 0.1mm to 0.5mm, the length of the glaucoma drainage implant 5 ranges from 1mm to 5mm; the curvature range of the glaucoma drainage implant 5 ranges from R4mm to R10mm.
相应的，导向管2的内壁直径范围为0.1mm～0.5mm，导向管2的外壁直径范围为0.1mm～1mm。Correspondingly, the diameter of the inner wall of the guide tube 2 ranges from 0.1 mm to 0.5 mm, and the diameter of the outer wall of the guide tube 2 ranges from 0.1 mm to 1 mm.
进一步的，弯曲导向管21的曲率与schlemm管的曲率相匹配，方便操作者的手部以较为舒服的角度将青光眼引流植入物5导入schlemm管中。Further, the curvature of the curved guide tube 21 matches the curvature of the schlemm canal, which facilitates the operator's hands to introduce the glaucoma drainage implant 5 into the schlemm canal at a more comfortable angle.
在图5中，弯曲导向管21的曲率范围：R4mm～R10mm，在图6中，第一弯曲导向管211的曲率范围：R4mm～R10mm，第二弯曲导向管212的曲率范围：R3mm～R8mm。In FIG. 5, the curvature range of the curved guide tube 21: R4mm-R10mm; in FIG. 6, the curvature range of the first curved guide tube 211: R4mm-R10mm, and the curvature range of the second curved guide tube 212: R3mm-R8mm.
进一步的，结合图8和图9，推送机构3包括固定架31以及安装在固定架31上的主齿轮32、中间齿轮33、推送齿条34。在固定架31上设置有第一固定杆301和第二固定杆302，主齿轮32可以环绕第一固定杆301进行转动，中间齿轮33可以环绕第二固定杆302进行转动。推送齿条34与中间齿轮33啮合，沿固定架31前后移动。Further, referring to FIG. 8 and FIG. 9 , the pushing mechanism 3 includes a fixed frame 31 and a main gear 32 , an intermediate gear 33 , and a pushing rack 34 installed on the fixed frame 31 . A first fixed rod 301 and a second fixed rod 302 are arranged on the fixed frame 31 , the main gear 32 can rotate around the first fixed rod 301 , and the intermediate gear 33 can rotate around the second fixed rod 302 . The pushing rack 34 meshes with the intermediate gear 33 and moves forward and backward along the fixed frame 31 .
主齿轮32至少部分外露于壳体1以形成旋钮，主齿轮32能够推动着青光眼引流植入物5在导向管2中前进，而主齿轮32在后退时，青光眼引流植入物5则处于静止状态。The main gear 32 is at least partly exposed to the housing 1 to form a knob. The main gear 32 can push the glaucoma drainage implant 5 forward in the guide tube 2, and when the main gear 32 is retreating, the glaucoma drainage implant 5 is in a static state.
主齿轮32外露于壳体1的旋钮部分可以设置有凸起或凹陷，让操作者感受到青光眼引流植入物5在推送过程中的推送距离。凸起或凹陷呈规律性分布，能有效地反馈主齿轮32的行程触觉；旋钮部分上还可以包裹有硅胶。The knob part of the main gear 32 exposed from the housing 1 may be provided with protrusions or depressions, so that the operator can feel the pushing distance of the glaucoma drainage implant 5 during the pushing process. The protrusions or depressions are regularly distributed, which can effectively feedback the travel tactile sensation of the main gear 32; the knob part can also be wrapped with silica gel.
主齿轮32通过中间齿轮33与推送齿条34传动连接，推送齿条34的前端连接有用于固定推丝4的固定块35。The main gear 32 is in transmission connection with the push rack 34 through the intermediate gear 33, and the front end of the push rack 34 is connected with a fixing block 35 for fixing the push wire 4.
推丝4的近端穿过该固定块35后向下弯折，最终与固定块35固定连接，固定块35通过插接的方式与推送齿条34的前端连接，在固定块35的靠近推送齿条34的前端的侧面上设置有插接柱351。The proximal end of the push wire 4 passes through the fixed block 35 and bends downwards, and finally is fixedly connected with the fixed block 35. The fixed block 35 is connected with the front end of the push rack 34 by plugging, and a plug post 351 is arranged on the side of the front end of the push rack 34 near the fixed block 35.
推送机构3的工作原理为：拨动主齿轮32后，中间齿轮33转动进而带动推送齿条34前后移动，固定块35同步进行前后移动，进而 带动推丝4在导向管2(导向管2保持静止)内前后移动；当推丝4向外移动时，能够将青光眼引流植入物5推出导向管2。The working principle of the push mechanism 3 is: after the main gear 32 is moved, the intermediate gear 33 rotates and then drives the push rack 34 to move back and forth, the fixed block 35 moves back and forth synchronously, and then drives the push wire 4 to move back and forth in the guide tube 2 (the guide tube 2 remains stationary); when the push wire 4 moves outward, the glaucoma drainage implant 5 can be pushed out of the guide tube 2.
进一步的，主齿轮32和中间齿轮33的传动比为0.2～5。优选主齿轮32和中间齿轮33的传动比大于1，即主齿轮32的转速比中间齿轮33要快，所以是减速，目的是保证操作者在手术的时候，青光眼引流植入物5是慢慢的从导向管2中进入到schlemm管，同时也避免了一部分误操作带来的手术风险。Further, the transmission ratio of the main gear 32 and the intermediate gear 33 is 0.2-5. Preferably, the transmission ratio of the main gear 32 and the intermediate gear 33 is greater than 1, that is, the rotation speed of the main gear 32 is faster than that of the intermediate gear 33, so it is decelerated. The purpose is to ensure that the glaucoma drainage implant 5 slowly enters the schlemm tube from the guide tube 2 when the operator performs surgery, and also avoids surgical risks caused by some misoperations.
进一步的，固定架31的材料可以是ABS、POM、PEEK、PVC、PET、尼龙、高分子材料、改性工程塑料、锌合金、铝合金、镁铝合金、不锈钢、铜、铁等。Further, the material of the fixing frame 31 may be ABS, POM, PEEK, PVC, PET, nylon, polymer material, modified engineering plastic, zinc alloy, aluminum alloy, magnesium aluminum alloy, stainless steel, copper, iron, etc.
进一步的，推丝4的直径为0.1mm～0.5mm，推丝可以采用SUS300系列/SUS400系列的不锈钢材料。Further, the diameter of the push wire 4 is 0.1mm-0.5mm, and the push wire can be made of SUS300 series/SUS400 series stainless steel.
进一步的，壳体1的侧面设置有防触发机构，防触发机构用于限制推送齿条34移动，防止推注器在未正式使用前因无动作而触发导致推注器失效，在移除该结构后，表明推注器已使用过，无法再进行恢复，给予操作者提示。Further, an anti-trigger mechanism is provided on the side of the housing 1, and the anti-trigger mechanism is used to limit the movement of the push rack 34, so as to prevent the injector from being triggered due to no action before official use, causing the injector to fail. After removing the structure, it indicates that the injector has been used and cannot be restored, and a reminder is given to the operator.
优选的，在图9中，防触发机构为限位插销6，限位插销6贯穿壳体1和推送齿条34。限位插销6的一端设置有捏板61，捏板61的设置方便限位插销6抽出。当然，防触发机构也额可以是圆形棒、方形棒、金属丝或细绳等。Preferably, in FIG. 9 , the anti-trigger mechanism is a limit pin 6 , and the limit pin 6 passes through the housing 1 and the push rack 34 . One end of the limit latch 6 is provided with a pinch plate 61, and the setting of the pinch plate 61 facilitates the extraction of the limit latch 6. Of course, the anti-trigger mechanism can also be a round rod, a square rod, a metal wire or a string, etc.
进一步的，结合图10和图11，壳体1的前端设置有导向管保护套7，导向管2贯穿导向管保护套7，导向管保护套7的尾部72安装在壳体1内。Further, referring to FIG. 10 and FIG. 11 , the front end of the casing 1 is provided with a guide tube protective sleeve 7 , the guide tube 2 runs through the guide tube protective sleeve 7 , and the tail portion 72 of the guide tube protective sleeve 7 is installed in the housing 1 .
导向管保护套7的头部71呈逐渐缩小的锥形，导向管保护套7的头部71的尖端与导向管2之间可以采用胶体固定，防止导向管2晃动。导向管保护套7的尾部72呈圆筒形，在导向管保护套7的尾部72上设置有限位卡块73。The head 71 of the guide tube protective cover 7 is tapered gradually, and colloid can be used between the tip of the head 71 of the guide tube protective cover 7 and the guide tube 2 to prevent the guide tube 2 from shaking. The tail portion 72 of the guide tube protection sleeve 7 is cylindrical, and a limiting block 73 is arranged on the tail portion 72 of the guide tube protection sleeve 7 .
结合图4和图11，壳体1包括可拆卸连接的第一壳体101和第二壳体102，可拆卸连接包括扣合、卡接、螺纹连接等方式。Referring to FIG. 4 and FIG. 11 , the housing 1 includes a first housing 101 and a second housing 102 that are detachably connected, and the detachable connection includes buckling, clamping, threaded connection and the like.
在图11中，第二壳体102的前端设置有安装台105，在安装台105上设置有用于放置导向管保护套7的尾部72的安装槽106，安装槽106的槽璧上还对应设置有与限位卡块73相适配的限位凹槽107；同理，在第一壳体101上也对应设置有安装台105、安装槽106、限位凹槽107。In FIG. 11 , the front end of the second housing 102 is provided with a mounting platform 105 , and the mounting platform 105 is provided with a mounting groove 106 for placing the tail portion 72 of the guide tube protective sleeve 7 . The groove wall of the mounting groove 106 is also provided with a corresponding limiting groove 107 that is compatible with the limiting block 73 ;
进一步的，导向管保护套7的内部设置有导向管固定套8，导向管2的近端贯穿导向管固定套8，并且导向管2的外壁与导向固定套8固定连接，该固定连接可以采用胶体进行固定。具体的，导向管固定套8的头部81穿插在导向管保护套7的尾部72内，并且通过胶体实现导向管固定套8的头部81与导向管保护套7的尾部72的固定；导向管固定套8的尾部82卡合在安装台105的侧壁上。Further, the inside of the guide tube protective sleeve 7 is provided with a guide tube fixing sleeve 8, the proximal end of the guide tube 2 runs through the guide tube fixing sleeve 8, and the outer wall of the guide tube 2 is fixedly connected to the guide fixing sleeve 8, and the fixed connection can be fixed by colloid. Specifically, the head 81 of the guide tube fixing sleeve 8 is inserted into the tail portion 72 of the guide tube protective sleeve 7, and the head 81 of the guide tube fixing sleeve 8 and the tail portion 72 of the guide tube protective sleeve 7 are fixed by colloid;
进一步的，壳体1的头部套设有多个防滑胶圈104，第一壳体101和第二壳体102上还设置有用于容纳防滑胶圈104的胶圈凹槽103。防滑胶圈104便于操作者抓握、刺激操作者感官，也起到了增加美观的作用。Further, a plurality of anti-slip rubber rings 104 are sheathed on the head of the housing 1 , and rubber ring grooves 103 for accommodating the anti-slip rubber rings 104 are also provided on the first housing 101 and the second housing 102 . The anti-slip rubber ring 104 is convenient for the operator to grasp, stimulates the operator's senses, and also plays a role in increasing the appearance.
进一步的，第二壳体102的内部具有一个平坦底面104，该平坦底面104用于固定推送机构3的固定架31，固定架31可以通过胶粘或者超声波焊接在平坦底面104上。Further, the second housing 102 has a flat bottom surface 104 inside, and the flat bottom surface 104 is used to fix the fixing bracket 31 of the pushing mechanism 3 , and the fixing bracket 31 can be glued or ultrasonically welded on the flat bottom surface 104 .
进一步的，第二壳体102的内部还设置有多个加强肋板108，加强肋板108用于增加壳体的强度，防止轻易损坏。Further, a plurality of reinforcing ribs 108 are provided inside the second housing 102, and the reinforcing ribs 108 are used to increase the strength of the housing and prevent easy damage.
进一步的，第一壳体101靠近主齿轮32的位置设置有指示标识9，表明推送的方向。指示标识9可以为凸起、凹陷、丝印或贴纸黏贴。Further, the position of the first housing 101 close to the main gear 32 is provided with an indicator mark 9, which indicates the pushing direction. The indication mark 9 can be a protrusion, a depression, a silk screen or a sticker.
进一步的，壳体1的形状呈中间大两头小、或者两头大中间小或者直杆型，适合单手操作。壳体1的直径范围为5mm～20mm，长度范围为5cm～20cm。Further, the shape of the housing 1 is large in the middle and small at the two ends, or large at both ends and small at the middle, or a straight rod type, which is suitable for one-handed operation. The diameter of the housing 1 ranges from 5 mm to 20 mm, and the length ranges from 5 cm to 20 cm.
进一步的，壳体1的材质可以是ABS、POM、PEEK、PVC、PET、尼龙、高分子材料、改性工程塑料、锌合金、铝合金、镁铝合金、不锈钢、铜、铁等。Further, the material of the housing 1 can be ABS, POM, PEEK, PVC, PET, nylon, polymer materials, modified engineering plastics, zinc alloy, aluminum alloy, magnesium aluminum alloy, stainless steel, copper, iron, etc.
进一步的，推注器的灭菌方式可以有：气体灭菌(环氧乙烷、甲醛、臭氧)、辐射灭菌(微波、紫外线(UV)、X射线和γ射线等)。Further, the sterilization methods of the injector may include: gas sterilization (ethylene oxide, formaldehyde, ozone), radiation sterilization (microwave, ultraviolet (UV), X-ray and γ-ray, etc.).
由此可见，本发明公开了一种推注器，用于将青光眼引流植入物推送至schlemm管中，包括壳体、导向管、推送机构、推丝；导向管与壳体连接，其远端用于容纳青光眼引流植入物，推丝设置在导向管的内部，推丝的远端与青光眼引流植入物抵接，推丝的近端露出导向管的近端、与壳体内部的推送机构连接；推送机构至少部分外露于壳体，用于向推丝提供推送力、以使青光眼引流植入物沿导向管推送至schlemm管内，在推送机构推送过程中，导向管的远端与schlemm管的外部抵接。本申请中的推注器推送效果好，精确度高，并且方便操作者使用。It can be seen that the present invention discloses a push injector, which is used to push the glaucoma drainage implant into the schlemm tube, including a housing, a guide tube, a pushing mechanism, and a pusher wire; the guide tube is connected to the housing, and its distal end is used to accommodate the glaucoma drainage implant, and the pusher wire is arranged inside the guide tube; The glaucoma drainage implant is pushed into the schlemm tube along the guide tube, and the distal end of the guide tube abuts against the outside of the schlemm tube during the pushing process of the pushing mechanism. The injector in the present application has good pushing effect, high precision and is convenient for operators to use.
以上所述仅为本发明的实施例，并非因此限制本发明的专利范围，凡是利用本发明说明书及附图内容所作的等效结构变换，或直接或间接运用在其他相关的技术领域，均同理包括在本发明的专利保护范围内。The above description is only an embodiment of the present invention, and does not limit the patent scope of the present invention. All equivalent structural transformations made by using the description of the present invention and the accompanying drawings, or directly or indirectly used in other related technical fields, are all included in the scope of patent protection of the present invention.

Claims (10)

  1. 一种推注器，用于将青光眼引流植入物推送至schlemm管中，其特征在于：包括壳体、导向管、推送机构、推丝；所述导向管与所述壳体连接，其远端用于容纳青光眼引流植入物，所述推丝设置在所述导向管的内部，所述推丝的远端与青光眼引流植入物抵接，所述推丝的近端露出所述导向管的近端、与所述壳体内部的所述推送机构连接；所述推送机构至少部分外露于所述壳体，用于向所述推丝提供推送力、以使青光眼引流植入物沿所述导向管推送至schlemm管内，在所述推送机构推送过程中，所述导向管的远端与schlemm管的外部抵接。A push injector for pushing the glaucoma drainage implant into the schlemm tube, characterized in that it includes a housing, a guiding tube, a pushing mechanism, and a pushing wire; the guiding tube is connected to the housing, and its distal end is used to accommodate the glaucoma drainage implant, the pushing wire is arranged inside the guiding tube, the distal end of the pushing wire abuts against the glaucoma drainage implant, and the proximal end of the pushing wire exposes the proximal end of the guiding tube and is connected to the pushing mechanism inside the housing; the pushing mechanism is at least partially exposed to the housing is used to provide a pushing force to the pushing wire so that the glaucoma drainage implant is pushed into the schlemm tube along the guide tube, and during the pushing process of the pushing mechanism, the distal end of the guide tube abuts against the outside of the schlemm tube.
  2. 根据权利要求1所述的推注器，其特征在于：所述推送机构包括固定架以及安装在所述固定架上的主齿轮、中间齿轮、推送齿条；所述主齿轮至少部分外露于所述壳体以形成旋钮，所述主齿轮通过所述中间齿轮与所述推送齿条传动连接，所述推送齿条的前端连接有用于固定所述推丝的固定块。The injector according to claim 1, wherein the pushing mechanism comprises a fixed frame, a main gear, an intermediate gear, and a pushing rack mounted on the fixing frame; the main gear is at least partially exposed to the housing to form a knob, the main gear is connected to the pushing rack through the intermediate gear, and the front end of the pushing rack is connected with a fixing block for fixing the pushing wire.
  3. 根据权利要求2所述的推注器，其特征在于：所述导向管包括远端的弯曲导向管和连接所述弯曲导向管的直线导向管。The injector according to claim 2, wherein the guide tube comprises a curved guide tube at a distal end and a straight guide tube connected to the curved guide tube.
  4. 根据权利要求3所述的推注器，其特征在于：所述弯曲导向管包括第一弯曲导向管和第二弯曲导向管，所述第二弯曲导向管连接所述直线导向管。The injector according to claim 3, wherein the curved guide tube comprises a first curved guide tube and a second curved guide tube, and the second curved guide tube is connected to the straight guide tube.
  5. 根据权利要求4所述的推注器，其特征在于：所述壳体的侧面设置有防触发机构，所述防触发机构用于限制所述推送齿条移动。The injector according to claim 4, wherein an anti-trigger mechanism is provided on the side of the housing, and the anti-trigger mechanism is used to limit the movement of the push rack.
  6. 根据权利要求5所述的推注器，其特征在于：所述防触发机构为限位插销，所述限位插销贯穿所述壳体和所述推送齿条。The injector according to claim 5, wherein the anti-trigger mechanism is a limit pin, and the limit pin passes through the housing and the push rack.
  7. 根据权利要求1至6任一项所述的推注器，其特征在于：所述壳体的前端设置有导向管保护套，所述导向管贯穿所述导向管保护套，所述导向管保护套的尾部安装在所述壳体内。The injector according to any one of claims 1 to 6, characterized in that: the front end of the housing is provided with a guide tube protection sleeve, the guide tube runs through the guide tube protection sleeve, and the tail of the guide tube protection sleeve is installed in the housing.
  8. 根据权利要求7所述的推注器，其特征在于：所述导向管保护 套的内部设置有导向管固定套，所述导向管的近端贯穿所述导向管固定套，并且所述导向管的外壁与所述导向固定套固定连接。The injector according to claim 7, wherein a guide tube fixing sleeve is provided inside the guide tube protective sleeve, the proximal end of the guide tube passes through the guide tube fixing sleeve, and the outer wall of the guide tube is fixedly connected to the guide fixing sleeve.
  9. 根据权利要求1至6任一项所述的推注器，其特征在于：所述壳体的头部套设有多个防滑胶圈。The injector according to any one of claims 1 to 6, characterized in that: the head of the housing is covered with a plurality of anti-slip rubber rings.
  10. 根据权利要求1至6任一项所述的推注器，其特征在于：所述壳体包括可拆卸连接的第一壳体和第二壳体。The injector according to any one of claims 1 to 6, wherein the housing includes a first housing and a second housing that are detachably connected.
PCT/CN2022/072622 2022-01-18 2022-01-18 Injector WO2023137602A1 (en)

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1249693A (en) * 1997-02-28 2000-04-05 斯塔尔外科公司 Glaucoma drain implanting device and method
US20050125003A1 (en) * 2003-12-05 2005-06-09 Leonard Pinchuk Glaucoma implant device
US20110112546A1 (en) * 2009-07-29 2011-05-12 Juan Jr Eugene De Ocular implant applier and methods of use
CN111557782A (en) * 2020-04-27 2020-08-21 中国科学院自动化研究所 Flexible microcatheter delivery mechanism for glaucoma viscoangioplasty
CN212214004U (en) * 2020-05-14 2020-12-25 江苏百视通医疗器械有限公司 Multiple implantation device for implant
CN213283754U (en) * 2020-05-29 2021-05-28 孙启锋 Full-penetration drainage nail for anterior chamber retrograde scleral fixation glaucoma
CN113397809A (en) * 2021-06-11 2021-09-17 北京奥京生物科技有限公司 Glaucoma minimally invasive surgery injector

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1249693A (en) * 1997-02-28 2000-04-05 斯塔尔外科公司 Glaucoma drain implanting device and method
US20050125003A1 (en) * 2003-12-05 2005-06-09 Leonard Pinchuk Glaucoma implant device
US20110112546A1 (en) * 2009-07-29 2011-05-12 Juan Jr Eugene De Ocular implant applier and methods of use
CN111557782A (en) * 2020-04-27 2020-08-21 中国科学院自动化研究所 Flexible microcatheter delivery mechanism for glaucoma viscoangioplasty
CN212214004U (en) * 2020-05-14 2020-12-25 江苏百视通医疗器械有限公司 Multiple implantation device for implant
CN213283754U (en) * 2020-05-29 2021-05-28 孙启锋 Full-penetration drainage nail for anterior chamber retrograde scleral fixation glaucoma
CN113397809A (en) * 2021-06-11 2021-09-17 北京奥京生物科技有限公司 Glaucoma minimally invasive surgery injector

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