WO2023065394A1 - Dispositif de thrombectomie - Google Patents

Dispositif de thrombectomie Download PDF

Info

Publication number
WO2023065394A1
WO2023065394A1 PCT/CN2021/127818 CN2021127818W WO2023065394A1 WO 2023065394 A1 WO2023065394 A1 WO 2023065394A1 CN 2021127818 W CN2021127818 W CN 2021127818W WO 2023065394 A1 WO2023065394 A1 WO 2023065394A1
Authority
WO
WIPO (PCT)
Prior art keywords
net bag
net
assembly
units
unit
Prior art date
Application number
PCT/CN2021/127818
Other languages
English (en)
Chinese (zh)
Inventor
夏顺
黄定国
Original Assignee
上海腾复医疗科技有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN202122513411.9U external-priority patent/CN216317840U/zh
Priority claimed from CN202122515872.XU external-priority patent/CN218528839U/zh
Priority claimed from CN202111215575.1A external-priority patent/CN113925568A/zh
Application filed by 上海腾复医疗科技有限公司 filed Critical 上海腾复医疗科技有限公司
Publication of WO2023065394A1 publication Critical patent/WO2023065394A1/fr

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/221—Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions

Definitions

  • the present application relates to the technical field of medical devices, in particular to a thrombectomy device.
  • Intravascular thrombosis is a systemic disease with a very wide range of pathogenesis, which may affect the upper and lower extremities, visceral vessels and carotid arteries.
  • myocardial infarction can occur; if it occurs in the brain, it can cause cerebral infarction; if it occurs in the lungs, it can cause pulmonary embolism...
  • deaths caused by thrombotic diseases account for 51% of the global death toll , far exceeding the deaths caused by tumors, infectious diseases, and respiratory diseases.
  • the main treatment methods for thrombosis include: anticoagulant drug therapy, interventional operation treatment and surgical operation.
  • anticoagulant drugs can be used for conservative treatment; for patients who cannot be treated by drugs, necessary surgery must be taken.
  • interventional therapy has less trauma, faster recovery, and is more acceptable to patients. The effect of interventional therapy is more limited by interventional devices.
  • thrombosis disease sites due to the diversity of thrombosis disease sites and the complexity of thrombus morphology, existing thrombus removal devices, such as thrombus removal stents, suction catheters, etc., generally have difficulty in completely removing thrombus, low success rate of one-time thrombus removal, and Fragmented thrombus is easy to escape and block the distal branch.
  • the purpose of some embodiments of the present application is to provide a thrombus removal device to solve the problems of low success rate of one-time thrombus removal and easy omission of fragmented thrombus.
  • an embodiment of the present invention provides a thrombectomy device, including:
  • An expandable and contractable net bag assembly includes at least one net bag unit; when the net bag assembly includes a plurality of net bag units, the plurality of net bag units are arranged at intervals along the axial direction; each net bag unit includes: a net bag The main body and a plurality of pull rods; the main body of the net bag is a flat net structure with a closed distal end, and the distal ends of the plurality of pull rods are respectively connected to the proximal ends of the main body of the net bag; and
  • Conveying assembly the far-end of described net bag unit is connected with described conveying assembly, and the near-end of a plurality of pull rods of described net bag unit gathers and is connected with described conveying assembly, forms the described net bag unit between described multiple pull rods
  • the opening; the conveying assembly is used to accommodate the net bag assembly in a compressed state, and can release the net bag assembly to an expanded state and pull the net bag assembly in the expanded state back into the catheter.
  • the net bag assembly includes a plurality of net bag units, and the plurality of net bag units are integrally woven and formed by a plurality of braiding wires.
  • each tie rod of the net bag unit is a twisted rod structure formed by merging the plurality of braiding wires.
  • the net bag main body includes a circumferential closed-loop support section and a distal filter screen smoothly connected to the distal end of the support section; the mesh density of the support section is smaller than the mesh density of the distal filter screen; The plurality of pull rods of the net bag unit are evenly spaced along the circumferential direction and form a tapered structure.
  • the core tube includes an elastic telescopic section passing between the distal end and the proximal end of the net bag assembly and a rigid section connected to the proximal end of the elastic telescopic section.
  • the ratio of the axial length of the pull rod of the net bag unit to the axial length of the net bag body is greater than or equal to 0.5 and less than or equal to 5, and the ratio of the maximum diameter of the net bag body to the axial length of the net bag body Can be greater than or equal to 2 and less than or equal to 20.
  • the thrombus removing device includes a plurality of net pocket units, and each net pocket unit is formed by interlacing braiding with a plurality of braiding wires.
  • the conveying assembly includes a core tube;
  • the net bag assembly also includes a proximal development fixing ring;
  • the core tube is passed through the plurality of net pocket units, the distal ends of the plurality of net pocket units are connected to the core tube, and a plurality of braided wires between two adjacent net pocket units are braided to connect the net tubes.
  • the connecting network pipe is sleeved on the core tube, and the plurality of pull rods of the proximal net unit among the plurality of net pocket units are converged and connected with the proximal developing and fixing ring, and the proximal developing and fixing ring is fixedly sleeved on the said plurality of net pocket units.
  • the core tube is passed through the plurality of net pocket units, the distal ends of the plurality of net pocket units are connected to the core tube, and a plurality of braided wires between two adjacent net pocket units are braided to connect the net tubes.
  • the connecting network pipe is sleeved on the core tube, and the plurality of pull rods of the proximal net unit among the plurality of net pocket units
  • the delivery assembly also includes:
  • the operating handle is a hollow tubular structure and its peripheral wall is provided with a chute extending along its own axial direction;
  • a sheath tube the proximal end of which is movably passed through the operating handle and is used to accommodate the mesh bag assembly in a contracted state;
  • the sheath tube connector is a tubular structure and is arranged on the inner distal end side of the operating handle, the distal end of the sheath tube connector is connected to the proximal end of the sheath tube; the core tube is passed through the sheath tube and The sheath tube connector is in and sealed with the proximal end of the sheath tube connector, and can move axially relative to the sheath tube and the sheath tube connector; the proximal end of the core tube passes through and is fixed on the the proximal end of the operating handle; and
  • the driving part is arranged in the chute, the inner end of the driving part is connected with the sheath connecting part, and can drive the sheath connecting part to drive the sheath along the chute in the operation
  • the handle is moved proximally inwardly to release the net bag assembly.
  • the operating handle includes a first shell and a second shell that engage with each other;
  • Both the first shell and the second shell are provided with a positioning post and a positioning hole; the positioning post cooperates with the positioning hole so that the first shell and the second shell are aligned and clamped.
  • the present invention at least has the following advantages and positive effects:
  • the net bag assembly of the thrombus removing device in the embodiment of the present invention may include one or more net bag units, wherein the plurality of net bag units are arranged at intervals along the axial direction, and the net bag body of each net bag unit adopts a flat net bag structure with a distal end closed, and its The proximal end is equipped with a plurality of pull rods that are converging and connected to the delivery assembly, so that each net bag unit not only has a large opening to facilitate the thrombus entering the net bag body, but also can select a thrombus retrieval device with an appropriate number of net bag units according to the length of the thrombus , encircle the thrombus in sections and take it out completely.
  • the thrombus removal device in the embodiment of the present invention helps to improve the success rate of one-time thrombus removal, and at the same time, it can effectively prevent the thrombus from escaping and blocking the distal blood vessel after being broken, and has better removal efficiency. Throttle effect.
  • Fig. 1 is a schematic structural view of a thrombectomy device provided by an embodiment of the present invention
  • Fig. 2 is a three-dimensional structural schematic diagram of the net bag assembly of the thrombus removing device provided by an embodiment of the present invention
  • FIG. 3 is a schematic structural view of the net bag assembly of the thrombus removal device provided by an embodiment of the present invention.
  • Fig. 4 is the schematic diagram of the weaving structure of the pull bar of the net bag unit of the bolt removing device provided by an embodiment of the present invention
  • Figures 5a and 5b are schematic diagrams of the weaving structure of the net bag unit of the thrombus removing device provided by an embodiment of the present invention
  • Fig. 6 is a schematic structural diagram of a thrombectomy device provided by another embodiment of the present invention.
  • Fig. 7 is a schematic structural view of the delivery assembly of the thrombectomy device provided by the embodiment of the present invention.
  • Fig. 8 is a schematic diagram of an exploded structure of the delivery assembly of the thrombectomy device provided by the embodiment of the present invention.
  • Fig. 9 is a schematic diagram of the connecting structure of the sheath tube and the core tube of the delivery assembly of the thrombectomy device provided by the embodiment of the present invention.
  • Fig. 10 is a partial structural schematic diagram of the thrombus removal device in which the net bag assembly provided by the embodiment of the present invention is in a compressed state;
  • Fig. 11 is a schematic diagram of the structure of the net bag assembly provided by the embodiment of the present invention in a released state.
  • orientation or positional relationship indicated by various terms indicating orientation or positional relationship such as “center”, “upper”, “lower”, “inner” and “outer” are based on the Orientation or positional relationship is only for convenience of description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed or operate in a specific orientation, and thus should not be construed as limiting the application.
  • connection and “connected” should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a direct connection, It can also be indirectly connected through an intermediary, and it can be the internal communication of two elements.
  • the near end and the far end mentioned in the present invention have the same meaning in terms of orientation, that is, in the state of use, the far end is the end away from the operator, the proximal end is the end close to the operator, and the operator is at the near end. Control the thrombectomy device.
  • an embodiment of the present invention provides a thrombus retrieval device, which is suitable for removing thrombus in a blood vessel, especially for rapid removal of thrombus with a large amount of thrombus.
  • the thrombus removal device of this embodiment mainly includes: an expandable and contractable net bag assembly and a delivery assembly connected with the net bag assembly.
  • the net bag assembly includes at least one net bag unit 1 .
  • the net bag unit 1 is an expandable and contractible thrombus retrieval structure, which can catch the thrombus from the distal end of the thrombus and pull it out of the body.
  • the expansion performance of the net bag unit 1 can be formed by using shape memory material.
  • the net bag assembly may include a net bag unit 1, which is suitable for removing a small amount of thrombus.
  • the net bag assembly can also include a plurality of net bag units 1.
  • the net bag assembly included a plurality of net bag units 1, the plurality of net bag units 1 were arranged at intervals along the axial direction. The number of 1 can be determined according to the length of the thrombus and the thrombus removal length of each net bag unit, so as to realize the rapid removal of a large number of thrombi.
  • Each net bag unit 1 includes: a net bag main body 11 and a plurality of pull rods 12 .
  • the net body 11 is a flat net structure with a closed distal end, and the distal ends of a plurality of pull rods 12 are respectively connected to the proximal ends of the net body 11 .
  • the far end of the net bag unit 1 is connected with the conveying assembly, and the proximal ends of the plurality of pull rods 12 of the net bag unit 1 converge and are connected with the conveying assembly, and the opening of the net bag unit 1 is formed between the plurality of pull rods 12 .
  • the delivery assembly is also configured to receive the net assembly in a compressed state, to release the net assembly to an expanded state, and to draw the expanded net assembly back into the catheter.
  • the net bag main body 11 of the net bag unit 1 can expand, the peripheral wall of the net bag main body 11 can attach to the inner wall of the blood vessel, and the thrombus can pass between multiple pull rods 12.
  • the opening of the net enters the main body 11 of the net bag and is caught by the main body 11 of the net bag, and then the net bag assembly and the thrombus are withdrawn into the catheter 100 through the delivery component, so that the thrombus can be taken out of the body.
  • a plurality of pull rods 12 of each net bag unit 1 are evenly spaced along the circumference and form a tapered structure, so that the net bag body 11 is evenly stressed, and it is convenient for the net bag body 11 to be retracted into the catheter 100 .
  • Each net bag unit 1 can take out the thrombus in a section of blood vessel length, and the blood vessel length can be the blood vessel length between the proximal side at the largest diameter of the net bag unit 1 and the distal end of the catheter, or the distal side of the adjacent net bag unit 1 The length of the blood vessel between the maximum diameter of the net bag unit 1 and the maximum diameter of the net bag unit 1 on the proximal side.
  • the net bag assembly can include two net bag units. It can be understood that the number of net bag units 1 can be more, such as four, to meet the demand for thrombus removal in a longer blood vessel length.
  • the net bag body 11 of the net bag unit 1 is used to pull out the thrombus in the length of the blood vessel it is responsible for along the inner wall of the blood vessel. With a larger opening, it is convenient for thrombus to enter the net bag main body 1 and be caught.
  • the multiple pull rods 12 of the net bag unit 1 are used to pull the net bag main body 11. At the same time, by adjusting the axial length of the pull rods 12, that is, the taper of the multiple pull rods, The retraction of the net bag body 11 into the catheter can be better controlled.
  • the ratio of the axial length of the pull rod 12 of the net bag unit 1 to the axial length of the net bag main body 11 can be greater than or equal to 0.5 and less than or equal to 5, and the maximum diameter of the net bag main body 11 and the axial length of the net bag main body 11
  • the ratio can be greater than or equal to 2 and less than or equal to 20, so that the net bag unit as a whole has a flat umbrella shape or an onion shape, so that the net bag unit has better thrombus removal performance.
  • a plurality of net bag units 1 can be integrally woven and formed by a plurality of braided wires.
  • a mesh is formed between the interlaced braided filaments, and the shape of the mesh can be a regular polygonal structure such as a rhombus or a rectangle.
  • the number of braiding filaments may be an even number.
  • the braided wire can be a shape-memory metal wire, such as a nickel-titanium alloy wire. Or use shape memory metal wire and polymer wire to weave together.
  • the mesh density of the walls around the main body 11 of the net bag can be the same.
  • the mesh density of the surrounding wall of the net bag body 11 can also vary in density.
  • the net bag body 11 includes a circumferential closed-loop support section 111 and a distal filter screen 112 smoothly connected to the distal end of the support section 111, the mesh density of the support section 111 may be smaller than the mesh density of the distal filter screen 112, Therefore, the main body of the net bag has better wall-attachment performance and better prevents thrombus from being missed.
  • proximal side of the support section 111 of the net bag main body 11 can continue to be woven into a net bag closing section, and the distal ends of a plurality of pull rods 12 are respectively connected to the proximal ends of the net bag closing section.
  • each pull rod 12 of the net bag unit 1 can be a twist rod structure that is combined with braiding through a plurality of braided wires, and the number of pull rods of the net bag unit can be determined according to the degree of difficulty of the weaving process and the retraction performance, for example, each The number of pull bars 12 of the net bag unit can be 3 or 4.
  • the The braiding filaments of the twist rod structure are dispersed, and then the next net bag unit is braided.
  • the delivery assembly may include: a core tube 2 , a guide head 3 , an operating handle 5 , a sheath tube 4 , a sheath tube connecting part 6 and a driving part 7 .
  • the net bag assembly can also include a proximal development fixing ring 13 . Please refer to Fig.
  • the core tube 2 is passed through the one net bag unit 1, and the distal end of the net bag unit 1 is connected to the core tube 2, and the proximal ends of a plurality of pull rods 12 are converged to connect the proximal ends A developing fixing ring 13 , the proximal developing fixing ring 13 is fixedly sleeved on the core tube 2 .
  • the net bag assembly includes a plurality of net bag units 1
  • the plurality of net bag units 2 are arranged at intervals along the axial direction and are integrally connected.
  • the core tube 2 is threaded through a plurality of net pocket units 1, and the distal ends of the plurality of net pocket units 1 are connected to the core tube 2, and a plurality of braided wires between two adjacent net pocket units 1 are braided into a connecting network tube 14, and there are 14 sets of connecting network tubes Located on the core tube 2 , the plurality of pull rods 12 of the proximal net bag unit 1 among the plurality of net bag units 1 are converged and connected to the developing fixing ring 13 , and the proximal developing fixing ring 13 is fixedly sleeved on the core tube 2 .
  • the net bag assembly can include two net bag units 1, the core tube 2 is sequentially passed through the two net bag units 1, and the distal end of the most distal net bag unit 1 is connected to the core tube 2, and the distance between the two net bag units 1 Connected through the connecting network pipe 14 , the plurality of pull rods 12 of the proximal net bag unit 1 converge to connect to the proximal developing and fixing ring 13 , and the proximal developing and fixing ring 13 is fixedly sleeved on the core tube 2 .
  • each net bag unit 1 in the plurality of net bag units can be formed by interlacing braiding with a plurality of braided wires, and then connected to the core tube 2 respectively.
  • the core tube 2 is connected.
  • the core tube 2 may include an elastic telescopic section passed through the net bag assembly and a rigid section connected to the proximal end of the elastic telescopic section.
  • the length of the elastic stretch section can be determined according to the stretchability of the material and the required stretch range.
  • the elastic expansion section of the core tube 2 can expand and contract with the net bag assembly in the axial direction, so that the net bag assembly can be accommodated and released by using the characteristics of the net bag assembly when it is axially extended, then radially compressed, and axially shortened, then radially expanded, which is not only easy to accommodate and release, and the expanded shape of the net bag assembly is not easily deformed.
  • the materials for the elastic stretch section of the core tube 2 include but are not limited to: pebax (nylon elastomer), TPU (ThermoPlastic Polyurethanes, thermoplastic polyurethane elastomer), TPE (Thermoplastic Elastomer, thermoplastic elastomer) or silica gel.
  • pebax nylon elastomer
  • TPU ThermoPlastic Polyurethanes, thermoplastic polyurethane elastomer
  • TPE Thermoplastic Elastomer, thermoplastic elastomer
  • silica gel silica gel.
  • the proximal end of the elastic telescopic section of the core tube 2 can be connected with the rigid section by heat welding or other physical connection methods. It can be understood that the core tube 2 as a whole can also adopt a rigid structure.
  • the guide head 3 is connected to the distal end of the core tube 2, and the distal end of the guide head 3 is a tip, which can adopt a tapered head structure, thereby improving the propulsion ability of the thrombectomy device in the blood vessel.
  • the operating handle 5 is a hollow tubular structure and its peripheral wall is provided with a sliding groove extending axially along itself.
  • the proximal end of the sheath tube 4 is movably threaded through the operating handle 5 .
  • the sheath tube connector 6 is a tubular structure and is disposed on the inner distal side of the operating handle 5 , and the distal end of the sheath tube connector 6 is connected to the proximal end of the sheath tube 4 .
  • the core tube 2 is passed through the sheath tube 4 and the sheath tube connector 6 and is in sealing connection with the proximal end of the sheath tube connector 6 , and can move axially relative to the sheath tube 4 and the sheath tube connector 6 .
  • the proximal end of the core tube 2 passes through and is fixed on the proximal end of the operating handle 5 .
  • the driver 7 is arranged in the chute, the inner end of the driver 7 is connected with the sheath connector 6, and the outer end of the driver 7 is exposed outside the chute, and the driver 7 can drive the sheath connector 6 to drive the sheath 4 along the slide.
  • the slot moves proximally within the operating handle 5 to release the net bag assembly. That is, the driving member 7 can drive the sheath tube 4 to slide axially relative to the core tube 2 in the operating handle 5 .
  • the operating handle 5 can be designed into a shape and size suitable for holding, and the driving part 7 can be designed into a shape and size suitable for finger operation.
  • the sheath tube 4 can be driven along the chute Move to the proximal end in the operating handle 5 to release the net bag assembly to the expanded state, so as to facilitate the thrombus removal operation.
  • the sheath tube connector 6 and the operating handle 5 can be locked by friction or other locking structures to prevent the sheath tube 4 from moving unintentionally.
  • the operating handle 5 may include a first shell 51 and a second shell 52 that are engaged with each other.
  • Both the first shell 51 and the second shell 52 are provided with a positioning post and a positioning hole, and the positioning post and the positioning hole cooperate to make the first shell 51 and the second shell 52 aligned and engaged.
  • the second housing 52 is provided with a positioning column 522 and a positioning hole 521, correspondingly, the first housing 51 is provided with a corresponding positioning hole and positioning column, the first housing 51 and the second housing 52 can be positioned through their respective The column and the positioning hole are aligned and clamped. It can be understood that the first shell 51 and the second shell 52 can also be aligned and snapped through other positioning structures, which is not specifically limited here.
  • the inner wall of the first shell 51 and/or the second shell 52 is provided with several criss-cross reinforcing ribs 523 to improve the overall strength of the operating handle 5 and better meet the operating requirements.
  • the delivery assembly may further include: an O-ring 61 disposed between the inner wall of the proximal end of the sheath connector 6 and the outer wall of the core tube 2 .
  • the sheath tube connector 6 and the core tube 2 are sealed and connected through an O-ring 61 . That is, the proximal end of the core tube 2 and the sheath tube connector 6 is in a sealed sliding connection, which can not only ensure the flexibility of the retraction operation of the sheath tube 4, but also prevent blood leakage during the operation.
  • the driving member 7 may include two operating buttons symmetrically arranged on the sheath tube connecting member 6 , and correspondingly, the sliding slots are symmetrically arranged on the peripheral wall of the operating handle 5 .
  • Each operation button may include a link 71 and an operation portion 72 .
  • the connecting rod 72 is located in the chute and can move along the chute. One end of the connecting rod 72 is connected with the sheath tube connector 61 , and the other end is connected with the operating part 71 .
  • the connecting rod 72 can move in the chute, and the operation part 71 is located outside the chute.
  • the operating portion 71 can be bent into a strip-shaped or sheet-shaped structure to form a roughly triangular cross-section, wherein the side wall of the operating portion 71 parallel to the chute is connected to the outer end of the connecting rod 72, and the operating portion 71
  • the other two side walls can be used as operating surfaces for finger operation to drive the sheath tube connector 6 to move axially within the operating handle 5 .
  • anti-slip lines 73 are also provided on the operating portion 71 to prevent fingers from slipping during operation.
  • the cross section of the operating handle 5 is substantially a chamfered rectangle.
  • the chute is symmetrically arranged on two mutually parallel side walls of the operating handle 5 .
  • the operating handle 5 is also provided with a scale line for indicating the distance that the sheath tube 4 moves axially along the operating handle 5 .
  • the scale line can be set on the two symmetrical long rectangular side wall surfaces on the operating handle 5, so that it is convenient to observe the distance of the sheath tube 4 retracting (that is, moving to the proximal end) from any side of the operating handle 5 during operation, so that the operator can control The release status of the net bag assembly. It can be understood that the scale line can also be provided only on one side surface of the operating handle 5, and no specific limitation is set here.
  • the length of the chute is the range within which the sheath tube 4 can move relative to the core tube 2 .
  • the delivery assembly may further include: a stress diffusion sheath 53 sheathed on the sheath tube 4 and fixed on the proximal end of the operating handle 5 .
  • the stress diffusion sleeve 13 is used to prevent the sheath tube 4 from buckling during the advancing process.
  • the distal end of the stress diffusion sleeve 13 is formed with an annular boss, and the inner wall of the proximal end of the operating handle 5 is provided with an annular groove.
  • the stress diffusion sleeve 13 can be made of silica gel.
  • the delivery device may also include an infusion tube, a first Luer connector 8 and a second Luer connector 9 .
  • One end of the infusion tube is connected to the peripheral wall of the sheath tube connector 6 and communicates with the gap between the sheath tube 4 and the core tube 2 .
  • the other end of the infusion tube is connected to the first Luer connector 8 .
  • the infusion tube can move in the chute, that is, the infusion tube and the driving member are located in the same chute.
  • the second Luer connector 9 is connected to the proximal end of the core tube 2 , and the distal end of the second Luer connector 9 is fixedly connected to the proximal end of the operating handle 5 , so that the proximal end of the core tube 2 is fixed on the sheath connector 6 .
  • Both the first Luer connector 8 and the second Luer connector 9 can be single-way or multi-way Luer connectors.
  • Physiological saline can be injected into the gap between the sheath tube 4 and the core tube 2 through the first Luer connector 8 and the infusion tube to discharge the air in the gap between the sheath tube 4 and the core tube 2 .
  • Physiological saline can be injected into the core tube 2 through the second Luer connector 9 to discharge the air in the core tube 2 .
  • thrombolytic agents or other functional liquids can be injected into the infusion tube and the core tube 2, and there is no specific limitation here.
  • the method of using the thrombectomy device in this embodiment is as follows:
  • the thrombectomy device of this embodiment can be used in conjunction with the catheter 100.
  • the sheath tube 4 equipped with the net bag assembly is inserted into the catheter 100 along the guide wire and pushed to the position of thrombus removal, and then the driving member is operated to pull back the sheath tube 4
  • the net bag assembly is released, and the degree of release of the net bag assembly can be judged by the scale line on the operating handle 5.
  • the operating handle 5 is retracted as a whole to withdraw the net bag assembly and thrombus into the catheter 100 and take them out of the body. .
  • the present invention has at least the following advantages and positive effects:
  • the net bag assembly of the thrombus removing device in the embodiment of the present invention may include one or more net bag units, wherein the plurality of net bag units are arranged at intervals along the axial direction, and the net bag body of each net bag unit adopts a flat net bag structure with a distal end closed, and its The proximal end is equipped with a plurality of pull rods that are converging and connected to the delivery assembly, so that each net bag unit not only has a large opening to facilitate the thrombus entering the net bag body, but also can select a thrombus retrieval device with an appropriate number of net bag units according to the length of the thrombus , encircle the thrombus in sections and take it out completely.
  • the thrombus removal device in the embodiment of the present invention helps to improve the success rate of one-time thrombus removal, and at the same time, it can effectively prevent the thrombus from escaping and blocking the distal blood vessel after being broken, and has better removal efficiency. Throttle effect.

Landscapes

  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgical Instruments (AREA)

Abstract

Dispositif de thrombectomie, comprenant un ensemble sac filet apte à se déployer et à se contracter et un ensemble de transport ; l'ensemble sac filet comprend au moins une unité de sac filet (1) ; lorsque l'ensemble sac filet comprend une pluralité d'unités de sac filet (1), la pluralité d'unités de sac filet (1) sont agencées à des intervalles dans la direction axiale ; chaque unité de sac filet (1) comprend un corps de sac filet (11) et une pluralité de tiges de traction (12) ; le corps de sac filet (11) présente une structure de sac filet plat ayant une extrémité distale fermée et les extrémités distales de la pluralité de tiges de traction (12) sont respectivement reliées à l'extrémité proximale du corps de sac filet (11) ; l'extrémité distale de l'unité de sac filet (1) est reliée à l'ensemble de transport et les extrémités proximales de la pluralité de tiges de traction (12) de l'unité de sac filet (1) sont convergentes et reliées à l'ensemble de transport ; une ouverture de l'unité de sac filet (1) est formée entre la pluralité de tiges de traction (12) ; l'ensemble de transport est utilisé pour recevoir l'ensemble sac filet dans un état comprimé et peut libérer l'ensemble sac filet vers un état déployé et ramener l'ensemble sac filet à l'état déployé dans un tube de guidage (100). Par conséquent, le taux de réussite d'une thrombectomie ponctuelle peut être augmenté et la fuite de thrombus peut être efficacement évitée.
PCT/CN2021/127818 2021-10-19 2021-11-01 Dispositif de thrombectomie WO2023065394A1 (fr)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
CN202122513411.9U CN216317840U (zh) 2021-10-19 2021-10-19 取栓支架输送装置
CN202122513411.9 2021-10-19
CN202122515872.XU CN218528839U (zh) 2021-10-19 2021-10-19 取栓装置
CN202122515872.X 2021-10-19
CN202111215575.1A CN113925568A (zh) 2021-10-19 2021-10-19 取栓装置
CN202111215575.1 2021-10-19

Publications (1)

Publication Number Publication Date
WO2023065394A1 true WO2023065394A1 (fr) 2023-04-27

Family

ID=86057879

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2021/127818 WO2023065394A1 (fr) 2021-10-19 2021-11-01 Dispositif de thrombectomie

Country Status (1)

Country Link
WO (1) WO2023065394A1 (fr)

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104768479A (zh) * 2012-11-06 2015-07-08 柯惠有限合伙公司 多枢轴血栓摘除术装置
CN107374700A (zh) * 2017-08-28 2017-11-24 北京赛铂医药科技有限公司 一种分段式血栓碎取装置
US20170354489A1 (en) * 2007-08-31 2017-12-14 BiO2 Medical, Inc. Tethered vena cava filter apparatus and method of using same
CN112472210A (zh) * 2020-12-15 2021-03-12 上海融脉医疗科技有限公司 一种血栓捕获和去除导管装置的血栓破碎收集机构
CN112890915A (zh) * 2020-12-30 2021-06-04 上海融脉医疗科技有限公司 一种血管内多节段式取栓支架及其输送装置
CN113081170A (zh) * 2021-05-06 2021-07-09 东南大学泰州生物医药与医疗器械研究院 多网兜式取栓支架及多网兜取栓***
CN113180781A (zh) * 2021-06-01 2021-07-30 上海融脉医疗科技有限公司 一种卷绕式网盘支架及其输送装置

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170354489A1 (en) * 2007-08-31 2017-12-14 BiO2 Medical, Inc. Tethered vena cava filter apparatus and method of using same
CN104768479A (zh) * 2012-11-06 2015-07-08 柯惠有限合伙公司 多枢轴血栓摘除术装置
CN107374700A (zh) * 2017-08-28 2017-11-24 北京赛铂医药科技有限公司 一种分段式血栓碎取装置
CN112472210A (zh) * 2020-12-15 2021-03-12 上海融脉医疗科技有限公司 一种血栓捕获和去除导管装置的血栓破碎收集机构
CN112890915A (zh) * 2020-12-30 2021-06-04 上海融脉医疗科技有限公司 一种血管内多节段式取栓支架及其输送装置
CN113081170A (zh) * 2021-05-06 2021-07-09 东南大学泰州生物医药与医疗器械研究院 多网兜式取栓支架及多网兜取栓***
CN113180781A (zh) * 2021-06-01 2021-07-30 上海融脉医疗科技有限公司 一种卷绕式网盘支架及其输送装置

Similar Documents

Publication Publication Date Title
CN205359559U (zh) 一种带有半封闭结构的血管取栓装置及其血栓治疗仪
US11871957B2 (en) Retrieval device
WO2022214020A1 (fr) Endoprothèse d'élimination de thrombus, système d'élimination de thrombus, dispositif d'élimination de thrombus, endoprothèse de rupture de thrombus et dispositif de rupture de thrombus
JP5914432B2 (ja) 回収システムおよびその使用方法
US8398694B2 (en) Over-the-wire interlock attachment/detachment mechanism
CN105662532A (zh) 一种带有半封闭结构的血管取栓装置及其血栓治疗仪
EP1355692B1 (fr) Catheters d'embolectomie
CN112617966A (zh) 取栓装置
US20070288038A1 (en) Medical Retrieval Devices and Methods
JP2004532683A (ja) 回収装置
CN105662533A (zh) 一种带有螺旋结构的血管取栓装置及其血栓治疗仪
CN105662534A (zh) 一种带有刺状结构的血管取栓装置及其血栓治疗仪
CN205359560U (zh) 一种带有螺旋结构的血管取栓装置及其血栓治疗仪
CN212630979U (zh) 取栓支架及取栓***
CN215018482U (zh) 取栓装置
CN217244648U (zh) 可变径取栓装置
CN114711896B (zh) 取栓装置
CN216317840U (zh) 取栓支架输送装置
CN113907837A (zh) 血管开通装置
CN217793233U (zh) 多功能血栓治疗装置
CN216439269U (zh) 血管开通装置
CN205339057U (zh) 一种带有刺状结构的血管取栓装置及其血栓治疗仪
WO2023065394A1 (fr) Dispositif de thrombectomie
CN113925568A (zh) 取栓装置
CN218528839U (zh) 取栓装置

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 21961136

Country of ref document: EP

Kind code of ref document: A1