WO2022242046A1 - 医学图像的展示方法及装置、电子设备、存储介质和计算机程序 - Google Patents

医学图像的展示方法及装置、电子设备、存储介质和计算机程序 Download PDF

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WO2022242046A1
WO2022242046A1 PCT/CN2021/128329 CN2021128329W WO2022242046A1 WO 2022242046 A1 WO2022242046 A1 WO 2022242046A1 CN 2021128329 W CN2021128329 W CN 2021128329W WO 2022242046 A1 WO2022242046 A1 WO 2022242046A1
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region
interest
medical image
image sequence
medical
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PCT/CN2021/128329
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English (en)
French (fr)
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段琦
张少霆
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上海商汤智能科技有限公司
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Publication of WO2022242046A1 publication Critical patent/WO2022242046A1/zh

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    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H30/00ICT specially adapted for the handling or processing of medical images
    • G16H30/20ICT specially adapted for the handling or processing of medical images for handling medical images, e.g. DICOM, HL7 or PACS
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06VIMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V10/00Arrangements for image or video recognition or understanding
    • G06V10/20Image preprocessing
    • G06V10/25Determination of region of interest [ROI] or a volume of interest [VOI]

Definitions

  • the present disclosure relates to the field of image technology, and in particular, to a method and device for displaying medical images, electronic equipment, storage media, and computer programs.
  • the present disclosure provides a technical solution for displaying medical images.
  • a method for displaying medical images including:
  • a second region of interest corresponding to the first region of interest is determined, wherein the second medical image sequence and the first medical image sequence are medical images of the same target object an image sequence, and the second medical image sequence and the first medical image sequence belong to different modalities or different phases;
  • a second medical image sequence after marking the second region of interest is displayed.
  • a second region of interest corresponding to the first region of interest is determined, wherein the second medical image sequence and the first The medical image sequence is a medical image sequence of the same target object, and the second medical image sequence and the first medical image sequence belong to different modalities or different phases, and the second medical image sequence after marking the second region of interest is displayed, by
  • This can automatically determine and display the corresponding regions of interest in medical image sequences of different modalities or different phases, without the need for users to manually mark regions of interest in multiple medical image sequences of different modalities or different phases, and without The user manually registers the regions of interest in multiple medical image sequences, which can reduce the complexity and difficulty of the user's analysis of multiple medical image sequences of different modalities or different phases, save user time, and facilitate users to quickly read slices, and can reduce the error of the region of interest determined in multiple medical image sequences of different modalities or different phases, that is, it can realize the Precise
  • the second medical image sequence can be quickly returned to The region of interest can improve the convenience for the user to view the region of interest of the medical image sequence again. According to this implementation manner, it is possible to provide the user with a shortcut function of jumping to the region of interest with one key.
  • the first target medical image is any one of the following medical images:
  • the medical image with the largest covered area wherein the covered medical image indicates that at least part of the area in the second medical image sequence belongs to the first A medical image of a region of interest, the covered region represents a region in the covered medical image that belongs to the second region of interest;
  • the medical image with the largest diameter of the covered area wherein the diameter is the distance between two points in the covered area;
  • the displaying the second medical image sequence after marking the second region of interest includes:
  • the first medical image sequence and the second medical image sequence after marking the region of interest can be displayed simultaneously through different windows in the same interface, so that it is convenient for users to simultaneously view multiple images of different modalities or different phases.
  • Medical image sequences and it is convenient for users to compare and comprehensively analyze corresponding regions of interest in multiple medical image sequences of different modalities or different phases.
  • the method further includes:
  • the counting the density information corresponding to the second region of interest includes: counting the density information in the second region of interest, and the density information in at least one third region of interest corresponding to the second region of interest Density information, wherein the medical image sequence in which the at least one third region of interest is located is in a different phase from the second medical image sequence;
  • the displaying the density information corresponding to the second ROI includes: displaying the second ROI according to the density information in the second ROI and the density information in the at least one third ROI.
  • a time density curve corresponding to the region of interest wherein the time density curve corresponding to the second region of interest represents a curve of changes in density information of tissues in the second region of interest over time.
  • the density information in the second region of interest by counting the density information in the second region of interest and the density information in at least one third region of interest corresponding to the second region of interest, and according to the density information in the second region of interest and The density information in the at least one third region of interest shows the time density curve corresponding to the second region of interest, thereby providing intuitive information about the density of the tissue in the second region of interest changing with time, thereby facilitating the user Analyze regions of interest with visually displayed time-density curves.
  • the method further includes:
  • the density information in the first reference area and the density information in the at least one second reference area display the time density curve corresponding to the first reference area, wherein the time corresponding to the first reference area
  • the density curve represents the curve of the density information of the tissue in the first reference area changing with time.
  • the density information in the first reference region near the second region of interest by counting the density information in the first reference region near the second region of interest, and the density information in at least one second reference region corresponding to the first reference region, and according to the density information in the first reference region
  • the density information of the density information, and the density information in at least one second reference region, showing the time density curve corresponding to the first reference region thereby providing intuitive information of the density of the normal tissue region near the region of interest changing with time, and being able to It is convenient for users to compare the region of interest with the normal tissue region.
  • the determining the first region of interest in the first medical image sequence includes:
  • a preset type of three-dimensional segmentation is performed based on the position of interest to obtain a first region of interest in the first medical image sequence.
  • the determining the first region of interest in the first medical image sequence includes:
  • the first region of interest in the first medical image sequence is obtained by performing a preset type of three-dimensional segmentation on the first medical image sequence, so that the first medical image sequence can be automatically segmented based on the preset type. Segmentation does not require manual segmentation by the user, reduces the complexity of user operations, saves user time, and can improve the accuracy of the determined region of interest.
  • the determining the second region of interest corresponding to the first region of interest in at least one second medical image sequence includes:
  • the position of the center of gravity of the first region of interest and the maximum distance from the center of gravity of the first region of interest to the boundary of the first region of interest determine the A second ROI corresponding to the first ROI.
  • the second Locating the region of interest by combining the position of the center of gravity of the first region of interest and the maximum distance from the center of gravity of the first region of interest to the boundary of the first region of interest, the second Locating the region of interest, whereby the efficiency and accuracy of determining the second region of interest in the at least one second medical image sequence can be improved.
  • a medical image display device including:
  • a first determination module configured to determine a first region of interest in a first medical image sequence
  • the second determination module is configured to determine a second region of interest corresponding to the first region of interest in at least one second medical image sequence, wherein the second medical image sequence and the first medical image
  • the sequence is a medical image sequence of the same target object, and the second medical image sequence and the first medical image sequence belong to different modalities or different phases;
  • the first display module is configured to display the second medical image sequence after marking the second region of interest.
  • the device further includes:
  • the second display module is configured to display the first target medical image in the second medical image sequence in response to the request for returning the second region of interest, wherein at least a partial area of the first target medical image belongs to The second region of interest.
  • the first target medical image is any one of the following medical images:
  • the medical image with the largest covered area wherein the covered medical image indicates that at least part of the area in the second medical image sequence belongs to the first A medical image of a region of interest, the covered region represents a region in the covered medical image that belongs to the second region of interest;
  • the medical image with the largest diameter of the covered area wherein the diameter is the distance between two points in the covered area;
  • the configuration of the first display module is:
  • the device further includes:
  • a first statistical module configured to count density information corresponding to the second region of interest
  • a third display module configured to display density information corresponding to the second region of interest.
  • the first statistical module is configured to: count density information in the second region of interest, and density information in at least one third region of interest corresponding to the second region of interest, wherein the at least A medical image sequence in which a third region of interest is located is in a different phase from the second medical image sequence;
  • the third display module is configured to: display the time density curve corresponding to the second region of interest according to the density information in the second region of interest and the density information in the at least one third region of interest , wherein the time density curve corresponding to the second region of interest represents a curve of the density information of the tissue in the second region of interest changing with time.
  • the device further includes:
  • the second statistical module is configured to count density information in a first reference region near the second region of interest, and density information in at least one second reference region corresponding to the first reference region, wherein the Both the first reference region and the at least one second reference region belong to normal tissue, and the medical image sequence where the at least one second reference region is located is in a different phase from the second medical image sequence;
  • the fourth display module is configured to display the time density curve corresponding to the first reference area according to the density information in the first reference area and the density information in the at least one second reference area, wherein the The time density curve corresponding to the first reference area represents a time-varying curve of the density information of the tissue in the first reference area.
  • the first determining module is configured to:
  • a preset type of three-dimensional segmentation is performed based on the position of interest to obtain a first region of interest in the first medical image sequence.
  • the first determining module is configured to:
  • a preset type of three-dimensional segmentation is performed on the first medical image sequence to obtain a first region of interest in the first medical image sequence.
  • the second determining module is configured to:
  • the position of the center of gravity of the first region of interest and the maximum distance from the center of gravity of the first region of interest to the boundary of the first region of interest determine the A second ROI corresponding to the first ROI.
  • an electronic device comprising: one or more processors; a memory configured to store executable instructions; wherein the one or more processors are configured to call the memory to store executable instructions to perform the above method.
  • a computer-readable storage medium on which computer program instructions are stored, and when the computer program instructions are executed by a processor, the above method is implemented.
  • a computer program including computer readable codes, and when the computer readable codes are run in an electronic device, a processor in the electronic device executes to implement the above method.
  • a second region of interest corresponding to the first region of interest is determined, wherein the first The second medical image sequence and the first medical image sequence are medical image sequences of the same target object, and the second medical image sequence and the first medical image sequence belong to different modalities or different phases, and the second region of interest is marked
  • the second medical image sequence which can automatically determine and display the corresponding regions of interest in medical image sequences of different modalities or different phases, without the need for users to manually Marking the region of interest does not require the user to manually register the region of interest in multiple medical image sequences, which can reduce the complexity and difficulty of the user's analysis of multiple medical image sequences of different modalities or different phases, saving User time, which is convenient for users to quickly read images, and can reduce the error of the region of interest determined in multiple medical image sequences of different modalities or different phases, that is, it can realize image recognition in different modalities or different phases
  • Fig. 1 shows a flow chart of a method for displaying medical images provided by an embodiment of the present disclosure.
  • Fig. 2 shows a schematic diagram of determining a first region of interest in a first medical image sequence in an application scenario of an embodiment of the present disclosure.
  • Fig. 3 shows a schematic diagram of displaying a sequence of medical images in different phases after a region of interest is marked on the same interface in an application scenario of an embodiment of the present disclosure.
  • Fig. 4 shows a schematic diagram of displaying medical image sequences of different modalities after marking a region of interest in the same interface in an application scenario of an embodiment of the present disclosure.
  • Fig. 5 shows a schematic diagram of displaying information of a region of interest in an application scenario of an embodiment of the present disclosure.
  • Fig. 6 shows a schematic diagram showing a time density curve in an application scenario of an embodiment of the present disclosure.
  • Fig. 7 shows a schematic structural diagram of a medical image display device provided by an embodiment of the present disclosure.
  • FIG. 8 shows a schematic structural diagram of an electronic device 800 provided by an embodiment of the present disclosure.
  • FIG. 9 shows a schematic structural diagram of an electronic device 1900 provided by an embodiment of the present disclosure.
  • Embodiments of the present disclosure provide a medical image display method and device, electronic equipment, a storage medium, and a computer program.
  • determining a first region of interest in a first medical image sequence, in at least one second medical image sequence determining a second region of interest corresponding to the first region of interest, wherein the second medical image sequence and the first medical image sequence are medical image sequences of the same target object, and the second medical image sequence and the first medical image sequence belong to Different modalities or different phases, and display the second medical image sequence after marking the second region of interest, so that the corresponding region of interest in the medical image sequence of different modalities or different phases can be automatically determined and displayed without Users manually mark regions of interest in multiple medical image sequences of different modalities or different phases, and there is no need for users to manually register regions of interest in multiple medical image sequences, which can reduce the need for users to analyze different modalities or The cumbersome and difficult operation of multiple medical image sequences of different phases saves user time, facilitates users to quickly read images, and can reduce the sensitivity
  • Fig. 1 shows a flow chart of a method for displaying medical images provided by an embodiment of the present disclosure.
  • the method for displaying medical images may be executed by a terminal device or other processing devices.
  • the terminal device may be user equipment (User Equipment, UE), mobile device, user terminal, terminal, personal digital assistant (Personal Digital Assistant, PDA), handheld device, computing device, vehicle-mounted device or wearable device, etc.
  • the method for displaying medical images may be implemented in a manner in which a processor invokes computer-readable instructions stored in a memory. As shown in FIG. 1 , the method for displaying medical images includes steps S11 to S13.
  • step S11 a first region of interest in a first medical image sequence is determined.
  • step S12 in at least one second medical image sequence, a second region of interest corresponding to the first region of interest is determined, wherein the second medical image sequence and the first medical image sequence are A medical image sequence of the same target object, and the second medical image sequence and the first medical image sequence belong to different modalities or different phases.
  • step S13 the second medical image sequence after marking the second region of interest is displayed.
  • a medical image sequence may refer to a sequence including a plurality of medical images. That is, the first sequence of medical images and the second sequence of medical images may each include a plurality of medical images.
  • the medical image sequence in the embodiment of the present disclosure may be a medical image sequence including liver, brain, lung, heart and other organs or parts, which is not limited here.
  • a modality may represent a type of medical imaging technique.
  • a modality corresponds to a medical imaging technique, and different modalities correspond to different medical imaging techniques.
  • the modality can be CT (Computed Tomography, computerized tomography), MRI (Magnetic Resonance Imaging, magnetic resonance imaging), PET (Positron Emission Computed Tomography, positron emission computed tomography), etc. Do limited.
  • a phase may represent a period of contrast agent development.
  • CT may include phases such as plain scan, arterial phase, portal vein phase, and portal delay phase;
  • MRI may include phases such as T1, T2, FLAIR, and DWI, which are not limited here.
  • different medical images belonging to any medical image sequence may belong to the same modality and the same phase. That is, each medical image in the first medical image sequence may belong to the same modality and the same phase, and each medical image in the second medical image sequence may belong to the same modality and the same phase.
  • different medical image sequences belong to different modalities and/or different phases. For example, each medical image in the first medical image sequence belongs to CT modality and plain scan phase, and each medical image in the second medical image sequence belongs to CT modality and arterial phase. For another example, each medical image in the first medical image sequence belongs to CT modality and portal vein phase, and each medical image in the second medical image sequence belongs to MRI modality and T1 phase.
  • the number of the second medical image sequence may be one or more.
  • the multiple second medical image sequences respectively belong to different modalities and/or different phases.
  • the first medical image sequence belongs to CT mode and plain scan period
  • the number of the second medical image sequence is 7, which respectively belong to CT mode, arterial phase, CT mode, portal vein phase, CT mode, and portal vein delay Period, MRI mode, T1 period, MRI mode, T2 period, MRI mode, FLAIR period, MRI mode, DWI period.
  • the medical image presentation method provided by the embodiments of the present disclosure may be respectively executed for each second medical image sequence.
  • the first region of interest in the first medical image sequence may be determined manually and/or automatically.
  • the first ROI represents a certain ROI in the first medical image sequence.
  • the region of interest in the embodiments of the present disclosure may be a three-dimensional region of interest, namely VoI (Volume of Interest), or a two-dimensional region of interest, namely RoI (Region of Interest).
  • the region of interest in the embodiments of the present disclosure may be a regular geometric shape, such as a sphere, an ellipsoid, a cube, etc., or an irregular geometric shape, which is not limited herein.
  • the determining the first region of interest in the first medical image sequence includes: in response to a selection operation for any position of any medical image in the first medical image sequence, Determining a location of interest; performing a preset type of three-dimensional segmentation based on the location of interest to obtain a first region of interest in the first medical image sequence.
  • the user can issue a selection operation for any position of any medical image in the first medical image sequence by means of single-click, double-click, long-press, and the like. For example, in response to detecting that the right mouse button is clicked on any position of any medical image in the first sequence of medical images, an option of "select VOI" pops up, and in response to the option of "select VOI" being selected, move the mouse The right-clicked location is identified as the location of interest.
  • the user can select any position of any medical image in the first medical image sequence as the position of interest through a selection operation.
  • the location of interest represents a location corresponding to the selection operation.
  • the information about the location of interest may include the number of layers of the medical image to which the location of interest belongs in the first medical image sequence, and the coordinates of the location of interest in the medical image to which it belongs.
  • the preset type may be a tumor, a nodule, a blood vessel, and the like.
  • Performing a preset type of three-dimensional segmentation based on the position of interest may refer to automatically segmenting a three-dimensional object of a preset type from the first medical image sequence based on the position of interest, and dividing the three-dimensional object obtained by segmentation
  • the 3D region of is used as the first region of interest.
  • the first region of interest includes the location of interest.
  • the position of interest is determined in response to a selection operation on any position of any medical image in the first medical image sequence, and a preset type of three-dimensional segmentation is performed based on the position of interest to obtain the second
  • the first ROI in a medical image sequence can be automatically segmented based on the location selected by the user, reducing the complexity of user operations, saving user time, and improving the accuracy of the determined ROI.
  • the determining the first region of interest in the first medical image sequence includes: performing a preset type of three-dimensional segmentation on the first medical image sequence to obtain the first medical image sequence The first region of interest in .
  • a three-dimensional object of a preset type may be automatically segmented from the first medical image sequence, and a three-dimensional area occupied by the segmented three-dimensional object may be used as the first region of interest.
  • the first region of interest in the first medical image sequence is obtained by performing a preset type of three-dimensional segmentation on the first medical image sequence, so that the first medical image sequence can be automatically segmented based on the preset type. Segmentation does not require manual segmentation by the user, reduces the complexity of user operations, saves user time, and can improve the accuracy of the determined region of interest.
  • the first region of interest may also be drawn manually by the user.
  • a sphere may be drawn in the first medical image sequence with the mouse clicked position as the center of the sphere and the dragging range as the radius, as the first region of interest.
  • the user can also manually draw the first ROI in other shapes, which is not limited here.
  • the type of the target object may be a person or an animal, that is, the first medical image sequence and the second medical image sequence may be the medical image sequences of the same person or the same animal.
  • the first medical image sequence and the second medical image sequence may be medical images containing the same organ or part of the same target object.
  • the first sequence of medical images and the second sequence of medical images are sequences of medical images of the liver of the same person.
  • the first medical image sequence and the second medical image sequence can be analyzed according to at least one of cross entropy, relative entropy, mutual information, etc. between the first medical image sequence and the second medical image sequence Rigid body registration is performed to obtain registration information between the first medical image sequence and the second medical image sequence.
  • the position of the second region of interest corresponding to the first region of interest can be determined in at least one second sequence of medical images information.
  • the first region of interest can be Non-rigid body registration, to determine position information of a second region of interest corresponding to the first region of interest in at least one second medical image sequence.
  • determining the second region of interest corresponding to the first region of interest includes: determining the center of gravity of the first region of interest position, and the maximum distance from the center of gravity of the first region of interest to the boundary of the first region of interest; according to the position of the center of gravity of the first region of interest, and the center of gravity of the first region of interest The maximum distance to the boundary of the first region of interest, in at least one second sequence of medical images, determines a second region of interest corresponding to the first region of interest.
  • the center of gravity of the first ROI is the center of the sphere
  • the maximum distance from the center of gravity of the first ROI to the boundary of the first ROI is the radius of the sphere.
  • the second sequence of medical images after marking the second region of interest may be displayed.
  • the second region of interest may cover part or all of the medical images in the second medical image sequence, that is, part or all of the medical images in the second medical image sequence contain image regions belonging to the second region of interest.
  • part or all of the image region in the medical image belongs to the second region of interest.
  • a part of the image area in the medical image belongs to the second ROI, and another part of the area does not belong to the second ROI.
  • the displaying the second medical image sequence after marking the second region of interest includes: in response to a request to simultaneously display the first medical image sequence and the second medical image sequence, at the The first medical image sequence after marking the first region of interest is displayed in a window, and the second medical image sequence after the second region of interest is marked is displayed in a second window.
  • the first medical image sequence and the second medical image sequence after marking the region of interest can be displayed simultaneously through different windows in the same interface, so that it is convenient for users to simultaneously view multiple images of different modalities or different phases. Medical image sequences, and it is convenient for users to compare and comprehensively analyze corresponding regions of interest in multiple medical image sequences of different modalities or different phases.
  • displaying the second medical image sequence after marking the second region of interest includes: responding to a request for displaying the second medical image sequence, displaying the second medical image sequence after marking the second region of interest image sequence.
  • the method further includes: in response to the request for returning the second region of interest, displaying The first target medical image in the second medical image sequence, wherein at least a partial area of the first target medical image belongs to the second region of interest.
  • the first target medical image is a medical image in the second medical image sequence
  • the first target medical image is a medical image covered by the second region of interest.
  • the second medical image sequence can be quickly returned to The region of interest can improve the convenience for the user to view the region of interest of the medical image sequence again. According to this implementation manner, it is possible to provide the user with a shortcut function of jumping to the region of interest with one key.
  • the first target medical image is any one of the following medical images: in the covered medical images of the second medical image sequence, the medical image with the largest area of the covered area, wherein the The covered medical image represents a medical image in the second medical image sequence, at least part of which belongs to the second region of interest, and the covered region represents that the covered medical image belongs to the second region of interest the area of the region; in the covered medical image, the medical image with the largest diameter of the covered region, wherein the diameter is the distance between two points in the covered region; the second region of interest The center of gravity of the medical image.
  • the diameter of the covered area may represent the maximum value between two points within the covered area.
  • the first target medical image in the second medical image sequence may be: the covered medical image in the second medical image sequence with the largest covered area. That is, in this example, the first target medical image may be the medical image with the largest area covered by the second region of interest in the second medical image sequence.
  • the first target medical image in the second medical image sequence may be: among the covered medical images in the second medical image sequence, the medical image with the largest diameter of the covered area.
  • the first target medical image in the second medical image sequence may be: the medical image where the center of gravity of the second region of interest is located.
  • the center of gravity of the second region of interest is the geometric center of the second region of interest.
  • the method further includes: displaying the first medical image sequence in response to a request for returning the first region of interest The second target medical image, wherein at least a part of the second target medical image belongs to the first region of interest.
  • the second target medical image is a medical image in the first medical image sequence
  • the second target medical image is a medical image covered by the first region of interest.
  • the second target medical image is any one of the following medical images: in the covered medical images of the first medical image sequence, the medical image with the largest area of the covered area, wherein the The covered medical image represents a medical image in the first medical image sequence, at least part of which belongs to the first region of interest, and the covered region represents that the covered medical image belongs to the first region of interest The area of the area; in the covered medical image, the medical image with the largest diameter of the covered area, wherein the diameter of the covered area represents the maximum value between two points in the covered area; the Medical image where the center of gravity of the first region of interest is located.
  • the medical image with the largest area of the covered region in the first medical image sequence or display the medical image with the largest diameter of the covered region in the first medical image sequence image, or display the medical image where the center of gravity of the first region of interest is located in the first medical image sequence, so that in the process of displaying the first medical image sequence, the key slice of the first region of interest can be quickly returned, so that the It is convenient for the user to quickly view the key slices of the first region of interest, and improve the efficiency of the user to view the first region of interest again.
  • the method further includes: counting density information corresponding to the second region of interest; displaying Density information corresponding to the second region of interest.
  • counting density information corresponding to the second region of interest may include counting density information in the second region of interest.
  • the density information in the second region of interest may include at least one of the average value, maximum value, minimum value, variance, standard deviation, etc. of the density in the second region of interest.
  • the pixel value of the medical image may reflect the density information of the tissue corresponding to the medical image.
  • the CT value that is, the HU value
  • the CT image may reflect the density information of the tissue corresponding to the CT image.
  • the pixel values of the pixels in the second region of interest may reflect the density information of the tissue included in the second region of interest.
  • automatic analysis of the density in the second region of interest can be realized, which can help The user quickly analyzes the second region of interest.
  • the displaying the density information corresponding to the second region of interest may include: displaying the density information in the second region of interest. For example, an average value of the density within the second region of interest may be displayed.
  • the counting the density information corresponding to the second region of interest includes: counting the density information in the second region of interest, and at least Density information in a third region of interest, wherein the medical image sequence in which the at least one third region of interest is located is in a different phase from the second medical image sequence; the displaying the second region of interest
  • the corresponding density information includes: displaying a time density curve corresponding to the second region of interest according to the density information in the second region of interest and the density information in the at least one third region of interest, wherein , the time density curve corresponding to the second region of interest represents a curve of the density information of the tissue in the second region of interest changing with time.
  • counting density information corresponding to the second region of interest may further include counting density information in at least one third region of interest corresponding to the second region of interest.
  • the medical image sequence where the third ROI is located and the second medical image sequence are medical image sequences of the same target object.
  • the medical image sequence where the third region of interest is located and the second medical image sequence may also be medical images of the same organ or part containing the same target object.
  • the medical image sequence where the third region of interest is located and the second medical image sequence are the same person's liver medical image sequence.
  • at least one third region of interest may include the first region of interest, that is, the medical image sequence in which a certain third region of interest is located, namely is the first medical image sequence.
  • the density information in any third ROI may include at least one of the average value, maximum value, minimum value, variance, and standard deviation of the density in the third ROI.
  • the density information in the second region of interest includes the average value of the density in the second region of interest, the average value of the density in the third region of interest, then, the time density curve corresponding to the second region of interest can represent A curve of the mean value of the density of the tissue in the second region of interest as a function of time.
  • the density information in the second region of interest by counting the density information in the second region of interest and the density information in at least one third region of interest corresponding to the second region of interest, and according to the density information in the second region of interest and at least The density information in a third region of interest displays the time density curve corresponding to the second region of interest, thereby providing intuitive information about the density of the tissue in the second region of interest changing with time, thereby facilitating the user to pass Visually displayed time-density curves analyze regions of interest.
  • the method further includes: counting density information in a first reference region near the second region of interest , and density information in at least one second reference region corresponding to the first reference region, wherein both the first reference region and the at least one second reference region belong to normal tissue, and the at least one second reference region
  • the medical image sequence where the reference area is located is in a different phase from the second medical image sequence; according to the density information in the first reference area and the density information in the at least one second reference area, display the second A time-density curve corresponding to a reference area, wherein the time-density curve corresponding to the first reference area represents a time-varying curve of tissue density information in the first reference area.
  • the first reference region is a normal tissue region near the second region of interest in the second medical image sequence.
  • the first reference area may be selected by the user, or may be automatically selected, which is not limited here.
  • the density information in the first reference area may include at least one of the average value, maximum value, minimum value, variance, standard deviation, etc. of the density in the first reference area; the density information in the second reference area may include At least one of the mean value, maximum value, minimum value, variance, standard deviation, etc. of the density within the second reference area.
  • the density information in the first reference area includes the average value of the density in the first reference area
  • the density information in the second reference area includes the average value of the density in the second reference area
  • the corresponding The time density curve may represent the curve of the average value of the density of the normal tissue in the first reference region as a function of time.
  • the density information, and the density information in at least one second reference region display the time density curve corresponding to the first reference region, thereby providing intuitive information about the density of the normal tissue region near the region of interest changing with time, which can facilitate The user compares the region of interest to the normal tissue region.
  • the method may further include: responding to the first position and A second location outside the second region of interest is selected, and density information of the first location and density information of the second location are determined; and a comparison result of the density information of the first location and the density information of the second location is displayed. According to this implementation manner, it is convenient for the user to perform density comparison analysis of a single point.
  • the method may further include: displaying the first region of interest during the display of the first medical image sequence The size of the volume of the region.
  • the method may further include: displaying the first region of interest during the display of the first medical image sequence The size of the longest diameter and the shortest diameter of the area.
  • the method may further include: displaying the second 2. The size of the volume of the region of interest.
  • the method may further include: displaying the second Two, the size of the longest diameter and the shortest diameter of the region of interest.
  • Fig. 2 shows a schematic diagram of determining a first region of interest in a first medical image sequence in an application scenario of an embodiment of the present disclosure.
  • the first medical image sequence includes 83 medical images, and the 24th medical image is currently displayed.
  • an option of "select VOI" pops up, and in response to the option of "select VOI" being selected, the position of the right mouse click is determined as the position of interest, And the three-dimensional segmentation of the tumor can be performed based on the position of interest to obtain the first region of interest.
  • second regions of interest corresponding to the first region of interest may be respectively determined in the seven second medical image sequences.
  • the first medical image sequence after marking the first region of interest and the second medical image sequence after marking the second region of interest can be displayed on the same interface .
  • Fig. 3 shows a schematic diagram of displaying a sequence of medical images in different phases after a region of interest is marked on the same interface in an application scenario of an embodiment of the present disclosure.
  • the region of interest is marked by a dashed circular box.
  • the medical image sequences of the plain scan phase, arterial phase, portal vein phase, and portal vein delay phase after the region of interest is marked can be displayed through different windows in the same interface.
  • a target medical image in a sequence of medical images may be presented in response to a request to return a region of interest.
  • a second target medical image in the first sequence of medical images may be presented in response to a request to return a first region of interest of the first sequence of medical images.
  • a second target medical image in the sequence of medical images in the portal venous phase may be displayed in response to a request to return a region of interest in the sequence of medical images in the portal venous phase.
  • the first target medical image in the second sequence of medical images may be displayed in response to a request to return the second region of interest of the second sequence of medical images. As shown in FIG.
  • the first target medical image in the medical image sequence of the unenhanced phase, the arterial phase, and the portal vein delay phase can be displayed.
  • target medical images in each medical image sequence in the interface may be displayed in response to the request for returning the region of interest.
  • the target medical image in the medical image sequence of the plain scan period, the arterial period, the portal vein period, and the portal vein delay period can be displayed, so that one-click jumps to each A region of interest for a medical image sequence.
  • Fig. 4 shows a schematic diagram of displaying medical image sequences of different modalities after marking a region of interest in the same interface in an application scenario of an embodiment of the present disclosure.
  • the region of interest is marked by a solid square box.
  • medical image sequences of different modalities after marking the region of interest can be displayed through different windows in the same interface.
  • the medical image sequence in the left window belongs to CT modality and portal vein phase
  • the medical image sequence in the right window belongs to MRI modality and DWI phase.
  • Fig. 5 shows a schematic diagram of displaying information of a region of interest in an application scenario of an embodiment of the present disclosure. As shown in Figure 5, information such as the location, volume, long and short diameter, density, standard deviation, and segmentation period of the region of interest can be displayed.
  • Fig. 6 shows a schematic diagram showing a time density curve in an application scenario of an embodiment of the present disclosure.
  • the time density curve corresponding to the region of interest and the time density curve corresponding to the normal tissue (that is, the reference region) can be displayed for comparison by the user.
  • this disclosure also provides medical image display devices, electronic equipment, computer-readable storage media, and programs, all of which can be used to implement any medical image display method provided by this disclosure.
  • the corresponding technical solutions and technical effects can be found in The corresponding records in the method part will not be repeated here.
  • Fig. 7 shows a schematic structural diagram of a medical image display device provided by an embodiment of the present disclosure.
  • the display device of the medical image includes:
  • the first determination module 71 is configured to determine a first region of interest in the first medical image sequence
  • the second determination module 72 is configured to determine a second region of interest corresponding to the first region of interest in at least one second medical image sequence, wherein the second medical image sequence and the first medical image sequence
  • the image sequence is a medical image sequence of the same target object, and the second medical image sequence and the first medical image sequence belong to different modalities or different phases;
  • the first display module 73 is configured to display the second medical image sequence after marking the second region of interest.
  • the device further includes:
  • the second display module is configured to display the first target medical image in the second medical image sequence in response to the request for returning the second region of interest, wherein at least a partial area of the first target medical image belongs to The second region of interest.
  • the first target medical image is any one of the following medical images:
  • the medical image with the largest covered area wherein the covered medical image indicates that at least part of the area in the second medical image sequence belongs to the first A medical image of a region of interest, the covered region represents a region in the covered medical image that belongs to the second region of interest;
  • the medical image with the largest diameter of the covered area wherein the diameter is the distance between two points in the covered area;
  • the first display module 73 is configured to:
  • the device further includes:
  • a first statistical module configured to count density information corresponding to the second region of interest
  • a third display module configured to display density information corresponding to the second region of interest.
  • the first statistical module is configured to: count density information in the second region of interest, and density information in at least one third region of interest corresponding to the second region of interest, wherein the at least A medical image sequence in which a third region of interest is located is in a different phase from the second medical image sequence;
  • the third display module is configured to: display the time density curve corresponding to the second region of interest according to the density information in the second region of interest and the density information in the at least one third region of interest , wherein the time density curve corresponding to the second region of interest represents a curve of the density information of the tissue in the second region of interest changing with time.
  • the device further includes:
  • the second statistical module is configured to count density information in a first reference region near the second region of interest, and density information in at least one second reference region corresponding to the first reference region, wherein the Both the first reference region and the at least one second reference region belong to normal tissue, and the medical image sequence where the at least one second reference region is located is in a different phase from the second medical image sequence;
  • the fourth display module is configured to display the time density curve corresponding to the first reference area according to the density information in the first reference area and the density information in the at least one second reference area, wherein the The time density curve corresponding to the first reference area represents a time-varying curve of the density information of the tissue in the first reference area.
  • the first determining module 71 is configured to:
  • a preset type of three-dimensional segmentation is performed based on the position of interest to obtain a first region of interest in the first medical image sequence.
  • the first determining module 71 is configured to:
  • a preset type of three-dimensional segmentation is performed on the first medical image sequence to obtain a first region of interest in the first medical image sequence.
  • the second determining module 72 is configured to:
  • the position of the center of gravity of the first region of interest and the maximum distance from the center of gravity of the first region of interest to the boundary of the first region of interest determine the A second ROI corresponding to the first ROI.
  • a second region of interest corresponding to the first region of interest is determined, wherein the first The second medical image sequence and the first medical image sequence are medical image sequences of the same target object, and the second medical image sequence and the first medical image sequence belong to different modalities or different phases, and the second region of interest is marked
  • the second medical image sequence which can automatically determine and display the corresponding regions of interest in medical image sequences of different modalities or different phases, without the need for users to manually Marking the region of interest does not require the user to manually register the region of interest in multiple medical image sequences, which can reduce the complexity and difficulty of the user's analysis of multiple medical image sequences of different modalities or different phases, saving User time, which is convenient for users to quickly read images, and can reduce the error of the region of interest determined in multiple medical image sequences of different modalities or different phases, that is, it can realize image recognition in different modalities or different phases
  • the functions or modules included in the device provided by the embodiments of the present disclosure can be used to execute the methods described in the above method embodiments, and its specific implementation and technical effects can refer to the descriptions of the above method embodiments, for It is concise and will not be repeated here.
  • An embodiment of the present disclosure also provides a computer-readable storage medium, on which computer program instructions are stored, and when the computer program instructions are executed by a processor, the foregoing method is implemented.
  • the computer-readable storage medium may be a non-volatile computer-readable storage medium, or may be a volatile computer-readable storage medium.
  • An embodiment of the present disclosure also proposes a computer program, including computer readable codes.
  • a processor in the electronic device executes and implements the foregoing method.
  • An embodiment of the present disclosure further provides a computer program product configured to store computer-readable instructions, and when the instructions are executed, the computer executes the operation of the method for displaying medical images provided in any of the above-mentioned embodiments.
  • An embodiment of the present disclosure also provides an electronic device, including: one or more processors; a memory configured to store executable instructions; wherein the one or more processors are configured to call the executable instructions stored in the memory instruction to perform the above method.
  • Electronic devices may be provided as terminals, servers, or other forms of devices.
  • FIG. 8 shows a schematic structural diagram of an electronic device 800 provided by an embodiment of the present disclosure.
  • the electronic device 800 may be a terminal such as a mobile phone, a computer, a digital broadcast terminal, a messaging device, a game console, a tablet device, a medical device, a fitness device, or a personal digital assistant.
  • electronic device 800 may include one or more of the following components: processing component 802, memory 804, power supply component 806, multimedia component 808, audio component 810, input/output (I/O) interface 812, sensor component 814 , and the communication component 816.
  • the processing component 802 generally controls the overall operations of the electronic device 800, such as those associated with display, telephone calls, data communications, camera operations, and recording operations.
  • the processing component 802 may include one or more processors 820 to execute instructions to complete all or part of the steps of the above method. Additionally, processing component 802 may include one or more modules that facilitate interaction between processing component 802 and other components. For example, processing component 802 may include a multimedia module to facilitate interaction between multimedia component 808 and processing component 802 .
  • the memory 804 is configured to store various types of data to support operations at the electronic device 800 . Examples of such data include instructions of any application or method configured to operate on the electronic device 800, contact data, phonebook data, messages, pictures, videos, and the like.
  • the memory 804 can be implemented by any type of volatile or non-volatile storage device or their combination, such as static random access memory (SRAM), electrically erasable programmable read-only memory (EEPROM), erasable Programmable Read Only Memory (EPROM), Programmable Read Only Memory (PROM), Read Only Memory (ROM), Magnetic Memory, Flash Memory, Magnetic or Optical Disk.
  • SRAM static random access memory
  • EEPROM electrically erasable programmable read-only memory
  • EPROM erasable Programmable Read Only Memory
  • PROM Programmable Read Only Memory
  • ROM Read Only Memory
  • Magnetic Memory Flash Memory
  • Magnetic or Optical Disk Magnetic Disk
  • the power supply component 806 provides power to various components of the electronic device 800 .
  • Power components 806 may include a power management system, one or more power supplies, and other components associated with generating, managing, and distributing power for electronic device 800 .
  • the multimedia component 808 includes a screen providing an output interface between the electronic device 800 and the user.
  • the screen may include a liquid crystal display (LCD) and a touch panel (TP). If the screen includes a touch panel, the screen may be implemented as a touch screen to receive input signals from a user.
  • the touch panel includes one or more touch sensors to sense touches, swipes, and gestures on the touch panel. The touch sensor may not only sense a boundary of a touch or swipe action, but also detect duration and pressure associated with the touch or swipe action.
  • the multimedia component 808 includes a front camera and/or a rear camera. When the electronic device 800 is in an operation mode, such as a shooting mode or a video mode, the front camera and/or the rear camera can receive external multimedia data. Each front camera and rear camera can be a fixed optical lens system or have focal length and optical zoom capability.
  • the audio component 810 is configured to output and/or input audio signals.
  • the audio component 810 includes a microphone (MIC), which is configured to receive an external audio signal when the electronic device 800 is in an operation mode, such as a call mode, a recording mode, and a voice recognition mode. Received audio signals may be further stored in memory 804 or sent via communication component 816 .
  • the audio component 810 also includes a speaker configured to output audio signals.
  • the I/O interface 812 provides an interface between the processing component 802 and a peripheral interface module, which may be a keyboard, a click wheel, a button, and the like. These buttons may include, but are not limited to: a home button, volume buttons, start button, and lock button.
  • Sensor assembly 814 includes one or more sensors configured to provide various aspects of status assessment for electronic device 800 .
  • the sensor component 814 can detect the open/closed state of the electronic device 800, the relative positioning of components, such as the display and the keypad of the electronic device 800, the sensor component 814 can also detect the electronic device 800 or a Changes in position of components, presence or absence of user contact with electronic device 800 , electronic device 800 orientation or acceleration/deceleration and temperature changes in electronic device 800 .
  • Sensor assembly 814 may include a proximity sensor configured to detect the presence of nearby objects in the absence of any physical contact.
  • the sensor assembly 814 may also include optical sensors, such as complementary metal-oxide-semiconductor (CMOS) or charge-coupled device (CCD) image sensors, for use in imaging applications.
  • CMOS complementary metal-oxide-semiconductor
  • CCD charge-coupled device
  • the sensor component 814 may also include an acceleration sensor, a gyroscope sensor, a magnetic sensor, a pressure sensor or a temperature sensor.
  • the communication component 816 is configured to facilitate wired or wireless communication between the electronic device 800 and other devices.
  • the electronic device 800 can access wireless networks based on communication standards, such as wireless networks (Wi-Fi), second-generation mobile communication technologies (2G), third-generation mobile communication technologies (3G), fourth-generation mobile communication technologies (4G )/long-term evolution (LTE) of universal mobile communication technology, fifth generation mobile communication technology (5G) or their combination.
  • the communication component 816 receives broadcast signals or broadcast related information from an external broadcast management system via a broadcast channel.
  • the communication component 816 also includes a near field communication (NFC) module to facilitate short-range communication.
  • the NFC module may be implemented based on Radio Frequency Identification (RFID) technology, Infrared Data Association (IrDA) technology, Ultra Wide Band (UWB) technology, Bluetooth (BT) technology and other technologies.
  • RFID Radio Frequency Identification
  • IrDA Infrared Data Association
  • UWB Ultra Wide Band
  • Bluetooth Bluetooth
  • electronic device 800 may be implemented by one or more application specific integrated circuits (ASICs), digital signal processors (DSPs), digital signal processing devices (DSPDs), programmable logic devices (PLDs), field programmable A programmable gate array (FPGA), controller, microcontroller, microprocessor or other electronic implementation configured to perform the methods described above.
  • ASICs application specific integrated circuits
  • DSPs digital signal processors
  • DSPDs digital signal processing devices
  • PLDs programmable logic devices
  • FPGA field programmable A programmable gate array
  • controller microcontroller, microprocessor or other electronic implementation configured to perform the methods described above.
  • a non-volatile computer-readable storage medium such as the memory 804 including computer program instructions, which can be executed by the processor 820 of the electronic device 800 to implement the above method.
  • FIG. 9 shows a schematic structural diagram of an electronic device 1900 provided by an embodiment of the present disclosure.
  • electronic device 1900 may be provided as a server.
  • electronic device 1900 includes processing component 1922 , which further includes one or more processors, and a memory resource represented by memory 1932 configured to store instructions executable by processing component 1922 , such as application programs.
  • the application programs stored in memory 1932 may include one or more modules each corresponding to a set of instructions.
  • the processing component 1922 is configured to execute instructions to perform the above method.
  • Electronic device 1900 may also include a power supply component 1926 configured to perform power management of electronic device 1900, a wired or wireless network interface 1950 configured to connect electronic device 1900 to a network, and an input-output (I/O) interface 1958 .
  • the electronic device 1900 can operate based on the operating system stored in the memory 1932, such as the Microsoft server operating system (Windows ServerTM), the graphical user interface-based operating system (Mac OS XTM) introduced by Apple Inc., and the multi-user and multi-process computer operating system (UnixTM). ), a free and open source Unix-like operating system (LinuxTM), an open source Unix-like operating system (FreeBSDTM), or similar.
  • a non-transitory computer-readable storage medium such as the memory 1932 including computer program instructions, which can be executed by the processing component 1922 of the electronic device 1900 to implement the above method.
  • the present disclosure can be a system, method and/or computer program product.
  • a computer program product may include a computer-readable storage medium carrying computer-readable program instructions configured to cause a processor to implement various aspects of the present disclosure.
  • a computer readable storage medium may be a tangible device that can retain and store instructions for use by an instruction execution device.
  • a computer readable storage medium may be, for example, but is not limited to, an electrical storage device, a magnetic storage device, an optical storage device, an electromagnetic storage device, a semiconductor storage device, or any suitable combination of the foregoing.
  • Computer-readable storage media include: portable computer diskettes, hard disks, random access memory (RAM), read-only memory (ROM), erasable programmable read-only memory (EPROM), or flash memory), static random access memory (SRAM), compact disc read only memory (CD-ROM), digital versatile disc (DVD), memory stick, floppy disk, mechanically encoded device, such as a printer with instructions stored thereon A hole card or a raised structure in a groove, and any suitable combination of the above.
  • RAM random access memory
  • ROM read-only memory
  • EPROM erasable programmable read-only memory
  • flash memory static random access memory
  • SRAM static random access memory
  • CD-ROM compact disc read only memory
  • DVD digital versatile disc
  • memory stick floppy disk
  • mechanically encoded device such as a printer with instructions stored thereon
  • a hole card or a raised structure in a groove and any suitable combination of the above.
  • computer-readable storage media are not to be construed as transient signals per se, such as radio waves or other freely propagating electromagnetic waves, electromagnetic waves propagating through waveguides or other transmission media (e.g., pulses of light through fiber optic cables), or transmitted electrical signals.
  • Computer-readable program instructions described herein may be downloaded from a computer-readable storage medium to a respective computing/processing device, or downloaded to an external computer or external storage device over a network, such as the Internet, a local area network, a wide area network, and/or a wireless network.
  • the network may include copper transmission cables, fiber optic transmission, wireless transmission, routers, firewalls, switches, gateway computers, and/or edge servers.
  • a network adapter card or a network interface in each computing/processing device receives computer-readable program instructions from the network and forwards the computer-readable program instructions for storage in a computer-readable storage medium in each computing/processing device .
  • Computer program instructions configured to perform the operations of the present disclosure may be assembly instructions, instruction set architecture (ISA) instructions, machine instructions, machine-dependent instructions, microcode, firmware instructions, state setting data, or Source or object code written in any combination, including object-oriented programming languages—such as Smalltalk, C++, etc., and conventional procedural programming languages—such as the “C” language or similar programming languages.
  • Computer readable program instructions may execute entirely on the user's computer, partly on the user's computer, as a stand-alone software package, partly on the user's computer and partly on a remote computer, or entirely on the remote computer or server implement.
  • the remote computer can be connected to the user computer through any kind of network, including a local area network (LAN) or a wide area network (WAN), or it can be connected to an external computer (such as via the Internet using an Internet service provider). connect).
  • LAN local area network
  • WAN wide area network
  • an electronic circuit such as a programmable logic circuit, field programmable gate array (FPGA), or programmable logic array (PLA)
  • FPGA field programmable gate array
  • PDA programmable logic array
  • These computer-readable program instructions may be provided to a processor of a general purpose computer, special purpose computer, or other programmable data processing apparatus to produce a machine such that when executed by the processor of the computer or other programmable data processing apparatus , producing an apparatus for realizing the functions/actions specified in one or more blocks in the flowchart and/or block diagram.
  • These computer-readable program instructions can also be stored in a computer-readable storage medium, and these instructions cause computers, programmable data processing devices and/or other devices to work in a specific way, so that the computer-readable medium storing instructions includes An article of manufacture comprising instructions for implementing various aspects of the functions/acts specified in one or more blocks in flowcharts and/or block diagrams.
  • each block in a flowchart or block diagram may represent a module, a portion of a program segment, or an instruction that includes one or more Executable instructions.
  • the functions noted in the block may occur out of the order noted in the figures. For example, two blocks in succession may, in fact, be executed substantially concurrently, or they may sometimes be executed in the reverse order, depending upon the functionality involved.
  • each block of the block diagrams and/or flowchart illustrations, and combinations of blocks in the block diagrams and/or flowchart illustrations can be implemented by a dedicated hardware-based system that performs the specified function or action , or may be implemented by a combination of dedicated hardware and computer instructions.
  • the computer program product can be specifically realized by means of hardware, software or a combination thereof.
  • the computer program product is embodied as a computer storage medium, and in another optional embodiment, the computer program product is embodied as a software product, such as a software development kit (Software Development Kit, SDK) etc. Wait.
  • a software development kit Software Development Kit, SDK
  • Embodiments of the present disclosure provide a medical image display method and device, electronic equipment, a storage medium, and a computer program, wherein the method includes: determining a first region of interest in a first medical image sequence; , determining a second region of interest corresponding to the first region of interest, wherein the second medical image sequence and the first medical image sequence are medical image sequences of the same target object, and the second The medical image sequence and the first medical image sequence belong to different modalities or different phases; and the second medical image sequence after marking the second region of interest is displayed.

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Abstract

提供了一种医学图像的展示方法及装置、电子设备、存储介质和计算机程序。方法包括:确定第一医学图像序列中的第一感兴趣区域(S11);在至少一个第二医学图像序列中,确定与第一感兴趣区域对应的第二感兴趣区域,其中,第二医学图像序列和第一医学图像序列为同一目标对象的医学图像序列,且所述第二医学图像序列与所述第一医学图像序列属于不同模态或者不同期相(S12);展示标记所述第二感兴趣区域后的第二医学图像序列(S13)。

Description

医学图像的展示方法及装置、电子设备、存储介质和计算机程序
相关申请的交叉引用
本申请基于申请号为202110537645.9、申请日为2021年05月18日,申请名称为“医学图像的展示方法及装置、电子设备和存储介质”的中国专利申请提出,并要求该中国专利申请的优先权,该中国专利申请的全部内容在此以引入方式结合在本申请中。
技术领域
本公开涉及图像技术领域,尤其涉及一种医学图像的展示方法及装置、电子设备、存储介质和计算机程序。
背景技术
医生在进行多模态和/或多期相的医学图像序列的阅片时,由于模态和/或期相的数量较大,且每个模态和/或每个期相的数据量也较大(即各个模态和/或各个期相均包含较大数量的医学图像),导致需要来回翻页。这不仅耗费时间,还需要医生准确地记忆感兴趣的片层及对应区域,导致难以实现快速阅片。
发明内容
本公开提供了一种医学图像的展示技术方案。
根据本公开的一方面,提供了一种医学图像的展示方法,包括:
确定第一医学图像序列中的第一感兴趣区域;
在至少一个第二医学图像序列中,确定与所述第一感兴趣区域对应的第二感兴趣区域,其中,所述第二医学图像序列和所述第一医学图像序列为同一目标对象的医学图像序列,且所述第二医学图像序列与所述第一医学图像序列属于不同模态或者不同期相;
展示标记所述第二感兴趣区域后的第二医学图像序列。
通过确定第一医学图像序列中的第一感兴趣区域,在至少一个第二医学图像序列中,确定与第一感兴趣区域对应的第二感兴趣区域,其中,第二医学图像序列和第一医学图像序列为同一目标对象的医学图像序列,且第二医学图像序列与第一医学图像序列属于不同模态或者不同期相,并展示标记第二感兴趣区域后的第二医学图像序列,由此能够自动确定并展示不同模态或者不同期相的医学图像序列中相应的感兴趣区域,无需用户在不同模态或者不同期相的多个医学图像序列中分别手动标记感兴趣区域,且无需用户对多个医学图像序列中的感兴趣区域进行手动配准,能够降低用户分析不同模态或者不同期相的多个医学图像序列的操作繁琐度和操作难度,节省用户时间,方便用户快速阅片,并能够减小在不同模态或者不同期相的多个医学图像序列中所确定的感兴趣区域的误差,即,能够实现在不同模态或者不同期相的多个医学图像序列中的感兴趣区域的精准分析。
在一种可能的实现方式中,在所述确定与所述第一感兴趣区域对应的第二感兴趣区域之后,所述方法还包括:
响应于返回所述第二感兴趣区域的请求,展示所述第二医学图像序列中的第一目标医学图像,其中,所述第一目标医学图像的至少部分区域属于所述第二感兴趣区域。
在该实现方式中,通过响应于返回第二感兴趣区域的请求,展示第二医学图像序列中的第一目标医学图像,由此在展示第二医学图像序列的过程中,能够快速返回第二感兴趣区域,从而能够提高用户再次查看医学图像序列的感兴趣区域的便捷性。根据该实现方式,能够为用户提供一键跳转至感兴趣区域的快捷功能。
在一种可能的实现方式中,所述第一目标医学图像为以下任意一个医学图像:
在所述第二医学图像序列的被覆盖医学图像中,被覆盖区域的面积最大的医学图像,其中,所述被覆盖医学图像表示所述第二医学图像序列中、至少部分区域属于所述第二感兴趣区域的医学图像,所述被覆盖区域表示所述被覆盖医学图像中属于所述第二感兴趣区域的区域;
在所述被覆盖医学图像中,被覆盖区域的直径最大的医学图像,其中,所述直径为所述被覆盖区域内的两点之间的距离;
所述第二感兴趣区域的重心所在的医学图像。
在该实现方式中,通过响应于返回第二感兴趣区域的请求,展示第二医学图像序列中被覆盖区域的面积最大的医学图像,或者展示第二医学图像序列中被覆盖区域的直径最大的医学图像,或者展示第二医学图像序列中第二感兴趣区域的重心所在的医学图像,由此在展示第二医学图像序列的过程中,能够快速返回第二感兴趣区域的关键片层,从而能够方便用户快速查看第二感兴趣区域的关键片层,提高用户再次查看第二感兴趣区域的效率。
在一种可能的实现方式中,所述展示标记所述第二感兴趣区域后的第二医学图像序列,包括:
响应于同时展示第一医学图像序列和第二医学图像序列的请求,在第一窗口中展示标记所述第一感兴趣区域后的第一医学图像序列,并在第二窗口中展示标记所述第二感兴趣区域后的第二医学图像序列。
根据该实现方式,能够在同一界面中,通过不同窗口同时展示标记感兴趣区域后的第一医学图像序列和第二医学图像序列,从而能够方便用户同时查看不同模态或者不同期相的多个医学图像序列,且方便用户对不同模态或者不同期相的多个医学图像序列中的相应的感兴趣区域进行比对及综合分析。
在一种可能的实现方式中,在所述确定与所述第一感兴趣区域对应的第二感兴趣区域之后,所述方法还包括:
统计所述第二感兴趣区域对应的密度信息;
展示所述第二感兴趣区域对应的密度信息。
在该实现方式中,通过自动统计第二感兴趣区域对应的密度信息,并展示第二感兴趣区域对应的密度信息,由此能够实现第二感兴趣区域内的密度的自动分析,从而能够帮助用户快速分析第二感兴趣区域。
在一种可能的实现方式中,
所述统计所述第二感兴趣区域对应的密度信息,包括:统计所述第二感兴趣区域内的密度信息,以及与所述第二感兴趣区域对应的至少一个第三感兴趣区域内的密度信息,其中,所述至少一个第三感兴趣区域所在的医学图像序列与所述第二医学图像序列属于不同期相;
所述展示所述第二感兴趣区域对应的密度信息,包括:根据所述第二感兴趣区域内的密度信息,以及所述至少一个第三感兴趣区域内的密度信息,展示所述第二感兴趣区域对应的时间密度曲线,其中,所述第二感兴趣区域对应的时间密度曲线表示所述第二感兴趣区域内的组织的密度信息随时间变化的曲线。
在该实现方式中,通过统计第二感兴趣区域内的密度信息以及与第二感兴趣区域对 应的至少一个第三感兴趣区域内的密度信息,并根据第二感兴趣区域内的密度信息以及至少一个第三感兴趣区域内的密度信息,展示第二感兴趣区域对应的时间密度曲线,由此能够提供第二感兴趣区域内的组织的密度随着时间变化的直观信息,从而能够方便用户通过直观展示的时间密度曲线分析感兴趣区域。
在一种可能的实现方式中,在所述确定与所述第一感兴趣区域对应的第二感兴趣区域之后,所述方法还包括:
统计所述第二感兴趣区域附近的第一参考区域内的密度信息,以及与所述第一参考区域对应的至少一个第二参考区域内的密度信息,其中,所述第一参考区域和所述至少一个第二参考区域均属于正常组织,所述至少一个第二参考区域所在的医学图像序列与所述第二医学图像序列属于不同期相;
根据所述第一参考区域内的密度信息,以及所述至少一个第二参考区域内的密度信息,展示所述第一参考区域对应的时间密度曲线,其中,所述第一参考区域对应的时间密度曲线表示所述第一参考区域内的组织的密度信息随时间变化的曲线。
在该实现方式中,通过统计第二感兴趣区域附近的第一参考区域内的密度信息,以及与第一参考区域对应的至少一个第二参考区域内的密度信息,并根据第一参考区域内的密度信息,以及至少一个第二参考区域内的密度信息,展示第一参考区域对应的时间密度曲线,由此能够提供感兴趣区域附近的正常组织区域的密度随着时间变化的直观信息,能够方便用户比对感兴趣区域与正常组织区域。
在一种可能的实现方式中,所述确定第一医学图像序列中的第一感兴趣区域,包括:
响应于针对所述第一医学图像序列中的任意一个医学图像的任意位置的选择操作,确定感兴趣位置;
基于所述感兴趣位置进行预设类型的三维分割,得到所述第一医学图像序列中的第一感兴趣区域。
在该实现方式中,通过响应于针对第一医学图像序列中的任意一个医学图像的任意位置的选择操作,确定感兴趣位置,并基于所述感兴趣位置进行预设类型的三维分割,得到第一医学图像序列中的第一感兴趣区域,由此能够基于用户选择的位置进行自动分割,降低用户操作繁琐度,节省用户时间,并能够提高所确定的感兴趣区域的准确性。
在一种可能的实现方式中,所述确定第一医学图像序列中的第一感兴趣区域,包括:
对第一医学图像序列进行预设类型的三维分割,得到所述第一医学图像序列中的第一感兴趣区域。
在该实现方式中,通过对第一医学图像序列进行预设类型的三维分割,得到第一医学图像序列中的第一感兴趣区域,由此能够基于预设类型对第一医学图像序列进行自动分割,无需用户手动分割,降低用户操作繁琐度,节省用户时间,并能够提高所确定的感兴趣区域的准确性。
在一种可能的实现方式中,所述在至少一个第二医学图像序列中,确定与所述第一感兴趣区域对应的第二感兴趣区域,包括:
确定所述第一感兴趣区域的重心的位置,以及所述第一感兴趣区域的重心至所述第一感兴趣区域的边界的最大距离;
根据所述第一感兴趣区域的重心的位置,以及所述第一感兴趣区域的重心至所述第一感兴趣区域的边界的最大距离,在至少一个第二医学图像序列中,确定与所述第一感兴趣区域对应的第二感兴趣区域。
在该实现方式中,通过结合第一感兴趣区域的重心的位置,以及第一感兴趣区域的重心至第一感兴趣区域的边界的最大距离,在至少一个第二医学图像序列中进行第二感兴趣区域的定位,由此能够提高在至少一个第二医学图像序列中确定第二感兴趣区域的 效率和准确性。
根据本公开的一方面,提供了一种医学图像的展示装置,包括:
第一确定模块,配置为确定第一医学图像序列中的第一感兴趣区域;
第二确定模块,配置为在至少一个第二医学图像序列中,确定与所述第一感兴趣区域对应的第二感兴趣区域,其中,所述第二医学图像序列和所述第一医学图像序列为同一目标对象的医学图像序列,且所述第二医学图像序列与所述第一医学图像序列属于不同模态或者不同期相;
第一展示模块,配置为展示标记所述第二感兴趣区域后的第二医学图像序列。
在一种可能的实现方式中,所述装置还包括:
第二展示模块,配置为响应于返回所述第二感兴趣区域的请求,展示所述第二医学图像序列中的第一目标医学图像,其中,所述第一目标医学图像的至少部分区域属于所述第二感兴趣区域。
在一种可能的实现方式中,所述第一目标医学图像为以下任意一个医学图像:
在所述第二医学图像序列的被覆盖医学图像中,被覆盖区域的面积最大的医学图像,其中,所述被覆盖医学图像表示所述第二医学图像序列中、至少部分区域属于所述第二感兴趣区域的医学图像,所述被覆盖区域表示所述被覆盖医学图像中属于所述第二感兴趣区域的区域;
在所述被覆盖医学图像中,被覆盖区域的直径最大的医学图像,其中,所述直径为所述被覆盖区域内的两点之间的距离;
所述第二感兴趣区域的重心所在的医学图像。
在一种可能的实现方式中,所述第一展示模块配置为:
响应于同时展示第一医学图像序列和第二医学图像序列的请求,在第一窗口中展示标记所述第一感兴趣区域后的第一医学图像序列,并在第二窗口中展示标记所述第二感兴趣区域后的第二医学图像序列。
在一种可能的实现方式中,所述装置还包括:
第一统计模块,配置为统计所述第二感兴趣区域对应的密度信息;
第三展示模块,配置为展示所述第二感兴趣区域对应的密度信息。
在一种可能的实现方式中,
所述第一统计模块配置为:统计所述第二感兴趣区域内的密度信息,以及与所述第二感兴趣区域对应的至少一个第三感兴趣区域内的密度信息,其中,所述至少一个第三感兴趣区域所在的医学图像序列与所述第二医学图像序列属于不同期相;
所述第三展示模块配置为:根据所述第二感兴趣区域内的密度信息,以及所述至少一个第三感兴趣区域内的密度信息,展示所述第二感兴趣区域对应的时间密度曲线,其中,所述第二感兴趣区域对应的时间密度曲线表示所述第二感兴趣区域内的组织的密度信息随时间变化的曲线。
在一种可能的实现方式中,所述装置还包括:
第二统计模块,配置为统计所述第二感兴趣区域附近的第一参考区域内的密度信息,以及与所述第一参考区域对应的至少一个第二参考区域内的密度信息,其中,所述第一参考区域和所述至少一个第二参考区域均属于正常组织,所述至少一个第二参考区域所在的医学图像序列与所述第二医学图像序列属于不同期相;
第四展示模块,配置为根据所述第一参考区域内的密度信息,以及所述至少一个第二参考区域内的密度信息,展示所述第一参考区域对应的时间密度曲线,其中,所述第一参考区域对应的时间密度曲线表示所述第一参考区域内的组织的密度信息随时间变化的曲线。
在一种可能的实现方式中,所述第一确定模块配置为:
响应于针对所述第一医学图像序列中的任意一个医学图像的任意位置的选择操作,确定感兴趣位置;
基于所述感兴趣位置进行预设类型的三维分割,得到所述第一医学图像序列中的第一感兴趣区域。
在一种可能的实现方式中,所述第一确定模块配置为:
对第一医学图像序列进行预设类型的三维分割,得到所述第一医学图像序列中的第一感兴趣区域。
在一种可能的实现方式中,所述第二确定模块配置为:
确定所述第一感兴趣区域的重心的位置,以及所述第一感兴趣区域的重心至所述第一感兴趣区域的边界的最大距离;
根据所述第一感兴趣区域的重心的位置,以及所述第一感兴趣区域的重心至所述第一感兴趣区域的边界的最大距离,在至少一个第二医学图像序列中,确定与所述第一感兴趣区域对应的第二感兴趣区域。
根据本公开的一方面,提供了一种电子设备,包括:一个或多个处理器;配置为存储可执行指令的存储器;其中,所述一个或多个处理器被配置为调用所述存储器存储的可执行指令,以执行上述方法。
根据本公开的一方面,提供了一种计算机可读存储介质,其上存储有计算机程序指令,所述计算机程序指令被处理器执行时实现上述方法。
根据本公开的一方面,提供了一种计算机程序,包括计算机可读代码,当所述计算机可读代码在电子设备中运行时,所述电子设备中的处理器执行实现上述方法。
在本公开实施例中,通过确定第一医学图像序列中的第一感兴趣区域,在至少一个第二医学图像序列中,确定与第一感兴趣区域对应的第二感兴趣区域,其中,第二医学图像序列和第一医学图像序列为同一目标对象的医学图像序列,且第二医学图像序列与第一医学图像序列属于不同模态或者不同期相,并展示标记第二感兴趣区域后的第二医学图像序列,由此能够自动确定并展示不同模态或者不同期相的医学图像序列中相应的感兴趣区域,无需用户在不同模态或者不同期相的多个医学图像序列中分别手动标记感兴趣区域,且无需用户对多个医学图像序列中的感兴趣区域进行手动配准,能够降低用户分析不同模态或者不同期相的多个医学图像序列的操作繁琐度和操作难度,节省用户时间,方便用户快速阅片,并能够减小在不同模态或者不同期相的多个医学图像序列中所确定的感兴趣区域的误差,即,能够实现在不同模态或者不同期相的多个医学图像序列中的感兴趣区域的精准分析。
应当理解的是,以上的一般描述和后文的细节描述仅是示例性和解释性的,而非限制本公开。
根据下面参考附图对示例性实施例的详细说明,本公开的其它特征及方面将变得清楚。
附图说明
此处的附图被并入说明书中并构成本说明书的一部分,这些附图示出了符合本公开的实施例,并与说明书一起用于说明本公开的技术方案。
图1示出本公开实施例提供的医学图像的展示方法的流程图。
图2示出本公开实施例的一种应用场景中确定第一医学图像序列中的第一感兴趣区域的示意图。
图3示出本公开实施例的一种应用场景中在同一界面中展示标记感兴趣区域后的不 同期相的医学图像序列的示意图。
图4示出本公开实施例的一种应用场景中在同一界面中展示标记感兴趣区域后的不同模态的医学图像序列的示意图。
图5示出本公开实施例的一种应用场景中展示感兴趣区域的信息的示意图。
图6示出本公开实施例的一种应用场景中展示时间密度曲线的示意图。
图7示出本公开实施例提供的医学图像的展示装置的结构示意图。
图8示出本公开实施例提供的一种电子设备800的结构示意图。
图9示出本公开实施例提供的一种电子设备1900的结构示意图。
具体实施方式
以下将参考附图详细说明本公开的各种示例性实施例、特征和方面。附图中相同的附图标记表示功能相同或相似的元件。尽管在附图中示出了实施例的各种方面,但是除非特别指出,不必按比例绘制附图。
在这里专用的词“示例性”意为“用作例子、实施例或说明性”。这里作为“示例性”所说明的任何实施例不必解释为优于或好于其它实施例。
本文中术语“和/或”,仅仅是一种描述关联对象的关联关系,表示可以存在三种关系,例如,A和/或B,可以表示:单独存在A,同时存在A和B,单独存在B这三种情况。另外,本文中术语“至少一种”表示多种中的任意一种或多种中的至少两种的任意组合,例如,包括A、B、C中的至少一种,可以表示包括从A、B和C构成的集合中选择的任意一个或多个元素。
另外,为了更好地说明本公开,在下文的具体实施方式中给出了众多的具体细节。本领域技术人员应当理解,没有某些具体细节,本公开同样可以实施。在一些实例中,对于本领域技术人员熟知的方法、手段、元件和电路未作详细描述,以便于凸显本公开的主旨。
本公开实施例提供了一种医学图像的展示方法及装置、电子设备、存储介质和计算机程序,通过确定第一医学图像序列中的第一感兴趣区域,在至少一个第二医学图像序列中,确定与第一感兴趣区域对应的第二感兴趣区域,其中,第二医学图像序列和第一医学图像序列为同一目标对象的医学图像序列,且第二医学图像序列与第一医学图像序列属于不同模态或者不同期相,并展示标记第二感兴趣区域后的第二医学图像序列,由此能够自动确定并展示不同模态或者不同期相的医学图像序列中相应的感兴趣区域,无需用户在不同模态或者不同期相的多个医学图像序列中分别手动标记感兴趣区域,且无需用户对多个医学图像序列中的感兴趣区域进行手动配准,能够降低用户分析不同模态或者不同期相的多个医学图像序列的操作繁琐度和操作难度,节省用户时间,方便用户快速阅片,并能够减小在不同模态或者不同期相的多个医学图像序列中所确定的感兴趣区域的误差,即,能够实现在不同模态或者不同期相的多个医学图像序列中的感兴趣区域的精准分析。
下面结合附图对本公开实施例提供的医学图像的展示方法进行详细的说明。
图1示出本公开实施例提供的医学图像的展示方法的流程图。在一种可能的实现方式中,所述医学图像的展示方法可以由终端设备或其它处理设备执行。其中,终端设备可以是用户设备(User Equipment,UE)、移动设备、用户终端、终端、个人数字助理(Personal Digital Assistant,PDA)、手持设备、计算设备、车载设备或者可穿戴设备等。在一些可能的实现方式中,所述医学图像的展示方法可以通过处理器调用存储器中存储的计算机可读指令的方式来实现。如图1所示,所述医学图像的展示方法包括步骤S11至步骤S13。
在步骤S11中,确定第一医学图像序列中的第一感兴趣区域。
在步骤S12中,在至少一个第二医学图像序列中,确定与所述第一感兴趣区域对应的第二感兴趣区域,其中,所述第二医学图像序列和所述第一医学图像序列为同一目标对象的医学图像序列,且所述第二医学图像序列与所述第一医学图像序列属于不同模态或者不同期相。
在步骤S13中,展示标记所述第二感兴趣区域后的第二医学图像序列。
在本公开实施例中,医学图像序列可以指包括多个医学图像的序列。即,第一医学图像序列和第二医学图像序列可以分别包括多个医学图像。本公开实施例中的医学图像序列可以是包括肝脏、脑、肺、心脏等器官或部位的医学图像序列,在此不做限定。
模态可以表示医学成像技术的类型。一种模态对应于一种医学成像技术,不同的模态对应于不同的医学成像技术。例如,模态可以为CT(Computed Tomography,电子计算机断层扫描)、MRI(Magnetic Resonance Imaging,磁共振成像)、PET(Positron Emission Computed Tomography,正电子发射型计算机断层显像)等等,在此不做限定。
期相可以表示造影剂显影的时段。例如,CT可以包括平扫期、动脉期、门静脉期、门脉延迟期等期相;MRI可以包括T1、T2、FLAIR、DWI等期相,在此不做限定。
在本公开实施例中,属于任意一个医学图像序列的不同医学图像,可以是属于相同模态和相同期相的。即,第一医学图像序列中的各个医学图像可以属于相同模态和相同期相,第二医学图像序列中的各个医学图像可以属于相同模态和相同期相。在本公开实施例中,不同的医学图像序列属于不同模态和/或不同期相。例如,第一医学图像序列中的各个医学图像均属于CT模态、平扫期,第二医学图像序列中的各个医学图像均属于CT模态、动脉期。又如,第一医学图像序列中的各个医学图像均属于CT模态、门静脉期,第二医学图像序列中的各个医学图像均属于MRI模态、T1期。
其中,第二医学图像序列的数量可以为一个或多个。在第二医学图像序列的数量为多个的情况下,多个第二医学图像序列分别属于不同模态和/或不同期相。例如,第一医学图像序列属于CT模态、平扫期,第二医学图像序列的数量为7个,分别属于CT模态、动脉期,CT模态、门静脉期,CT模态、门脉延迟期,MRI模态、T1期,MRI模态、T2期,MRI模态、FLAIR期,MRI模态、DWI期。在第二医学图像序列的数量为多个的情况下,可以针对各个第二医学图像序列,分别执行本公开实施例提供的医学图像的展示方法。
在本公开实施例中,可以采用手动和/或自动的方式,确定第一医学图像序列中的第一感兴趣区域。其中,第一感兴趣区域表示第一医学图像序列中的某一感兴趣区域。任一医学图像序列中可以有一个或多个感兴趣区域。本公开实施例中的感兴趣区域可以为三维的感兴趣区域,即VoI(Volume of Interest),也可以为二维的感兴趣区域,即RoI(Region of Interest)。本公开实施例中的感兴趣区域可以为规则的几何形状,例如球体、椭球体、立方体等,也可以为不规则的几何形状,在此不做限定。
在一种可能的实现方式中,所述确定第一医学图像序列中的第一感兴趣区域,包括:响应于针对所述第一医学图像序列中的任意一个医学图像的任意位置的选择操作,确定感兴趣位置;基于所述感兴趣位置进行预设类型的三维分割,得到所述第一医学图像序列中的第一感兴趣区域。
在该实现方式中,用户可以通过单击、双击、长按等方式,发出针对第一医学图像序列中的任意一个医学图像的任意位置的选择操作。例如,可以响应于检测到鼠标右键单击第一医学图像序列中的任意一个医学图像的任意位置,弹出“选择VOI”的选项,并可以响应于该“选择VOI”的选项被选择,将鼠标右键单击的位置确定为感兴趣位置。根据该实现方式,用户可以通过选择操作,选择第一医学图像序列中的任意一个医学图 像的任意位置作为感兴趣位置。其中,所述感兴趣位置表示所述选择操作对应的位置。所述感兴趣位置的信息,可以包括所述感兴趣位置所属的医学图像在第一医学图像序列中的层数,以及所述感兴趣位置在所属的医学图像中的坐标。
在该实现方式中,预设类型可以是肿瘤、结节、血管等。基于所述感兴趣位置进行预设类型的三维分割,可以指基于所述感兴趣位置,从第一医学图像序列中自动分割出属于预设类型的三维对象,并将分割得到的三维对象所占的三维区域作为第一感兴趣区域。在该实现方式中,第一感兴趣区域包括所述感兴趣位置。
在该实现方式中,通过响应于针对第一医学图像序列中的任意一个医学图像的任意位置的选择操作,确定感兴趣位置,并基于所述感兴趣位置进行预设类型的三维分割,得到第一医学图像序列中的第一感兴趣区域,由此能够基于用户选择的位置进行自动分割,降低用户操作繁琐度,节省用户时间,并能够提高所确定的感兴趣区域的准确性。
在另一种可能的实现方式中,所述确定第一医学图像序列中的第一感兴趣区域,包括:对第一医学图像序列进行预设类型的三维分割,得到所述第一医学图像序列中的第一感兴趣区域。在该实现方式中,可以从第一医学图像序列中自动分割出属于预设类型的三维对象,并将分割得到的三维对象所占的三维区域作为第一感兴趣区域。在该实现方式中,通过对第一医学图像序列进行预设类型的三维分割,得到第一医学图像序列中的第一感兴趣区域,由此能够基于预设类型对第一医学图像序列进行自动分割,无需用户手动分割,降低用户操作繁琐度,节省用户时间,并能够提高所确定的感兴趣区域的准确性。
在另一种可能的实现方式中,还可以由用户手动绘制第一感兴趣区域。例如,可以以鼠标点击的位置为球心,以拖动范围为半径,在第一医学图像序列中绘制球体,作为第一感兴趣区域。当然,用户也可以手动绘制其他形状的第一感兴趣区域,在此不做限定。
在本公开实施例中,目标对象的类型可以是人或者动物,即,第一医学图像序列和第二医学图像序列可以是同一个人或者同一个动物的医学图像序列。另外,第一医学图像序列和第二医学图像序列可以是包含同一目标对象的同一器官或部位的医学图像。例如,第一医学图像序列和第二医学图像序列是同一个人的肝脏的医学图像序列。
在本公开实施例中,可以根据第一医学图像序列和第二医学图像序列之间的交叉熵、相对熵、互信息等中的至少之一,对第一医学图像序列和第二医学图像序列进行刚体配准,得到第一医学图像序列和第二医学图像序列之间的配准信息。根据所述配准信息,以及第一感兴趣区域在第一医学图像序列中的位置信息,可以在至少一个第二医学图像序列中确定与第一感兴趣区域对应的第二感兴趣区域的位置信息。其中,在第一感兴趣区域内的组织为非刚体的情况下,可以根据第一感兴趣区域在第一医学图像序列中的位置信息,以及所述配准信息,针对第一感兴趣区域进行非刚体配准,以在至少一个第二医学图像序列中确定与第一感兴趣区域对应的第二感兴趣区域的位置信息。
在一种可能的实现方式中,所述在至少一个第二医学图像序列中,确定与所述第一感兴趣区域对应的第二感兴趣区域,包括:确定所述第一感兴趣区域的重心的位置,以及所述第一感兴趣区域的重心至所述第一感兴趣区域的边界的最大距离;根据所述第一感兴趣区域的重心的位置,以及所述第一感兴趣区域的重心至所述第一感兴趣区域的边界的最大距离,在至少一个第二医学图像序列中,确定与所述第一感兴趣区域对应的第二感兴趣区域。例如,若第一感兴趣区域为球体,则第一感兴趣区域的重心为球体的球心,第一感兴趣区域的重心至第一感兴趣区域的边界的最大距离为球体的半径。在该实现方式中,通过结合第一感兴趣区域的重心的位置,以及第一感兴趣区域的重心至第一感兴趣区域的边界的最大距离,在至少一个第二医学图像序列中进行第二感兴趣区域的 定位,由此能够提高在至少一个第二医学图像序列中确定第二感兴趣区域的效率和准确性。
在本公开实施例中,在至少一个第二医学图像序列中确定与第一感兴趣区域对应的第二感兴趣区域之后,可以展示标记第二感兴趣区域后的第二医学图像序列。其中,第二感兴趣区域可以覆盖第二医学图像序列中的部分或全部医学图像,即,第二医学图像序列中的部分或全部医学图像中,包含属于第二感兴趣区域的图像区域。对于第二医学图像序列中被第二感兴趣区域覆盖的任一医学图像,该医学图像中的部分或全部图像区域属于第二感兴趣区域。通常,对于第二医学图像序列中被第二感兴趣区域覆盖的任一医学图像,该医学图像中的一部分图像区域属于第二感兴趣区域,另一部分区域不属于第二感兴趣区域。在展示第二医学图像序列中被第二感兴趣区域覆盖的任一医学图像时,可以在该医学图像中标记出属于第二感兴趣区域的图像区域。
在一种可能的实现方式中,所述展示标记所述第二感兴趣区域后的第二医学图像序列,包括:响应于同时展示第一医学图像序列和第二医学图像序列的请求,在第一窗口中展示标记所述第一感兴趣区域后的第一医学图像序列,并在第二窗口中展示标记所述第二感兴趣区域后的第二医学图像序列。根据该实现方式,能够在同一界面中,通过不同窗口同时展示标记感兴趣区域后的第一医学图像序列和第二医学图像序列,从而能够方便用户同时查看不同模态或者不同期相的多个医学图像序列,且方便用户对不同模态或者不同期相的多个医学图像序列中的相应的感兴趣区域进行比对及综合分析。
在另一种可能的实现方式中,展示标记第二感兴趣区域后的第二医学图像序列,包括:响应于展示第二医学图像序列的请求,展示标记第二感兴趣区域后的第二医学图像序列。
在一种可能的实现方式中,在所述确定与所述第一感兴趣区域对应的第二感兴趣区域之后,所述方法还包括:响应于返回所述第二感兴趣区域的请求,展示所述第二医学图像序列中的第一目标医学图像,其中,所述第一目标医学图像的至少部分区域属于所述第二感兴趣区域。在该实现方式中,第一目标医学图像是第二医学图像序列中的医学图像,且第一目标医学图像是被第二感兴趣区域覆盖的医学图像。在该实现方式中,通过响应于返回第二感兴趣区域的请求,展示第二医学图像序列中的第一目标医学图像,由此在展示第二医学图像序列的过程中,能够快速返回第二感兴趣区域,从而能够提高用户再次查看医学图像序列的感兴趣区域的便捷性。根据该实现方式,能够为用户提供一键跳转至感兴趣区域的快捷功能。
作为该实现方式的一个示例,所述第一目标医学图像为以下任意一个医学图像:在所述第二医学图像序列的被覆盖医学图像中,被覆盖区域的面积最大的医学图像,其中,所述被覆盖医学图像表示所述第二医学图像序列中、至少部分区域属于所述第二感兴趣区域的医学图像,所述被覆盖区域表示所述被覆盖医学图像中属于所述第二感兴趣区域的区域;在所述被覆盖医学图像中,被覆盖区域的直径最大的医学图像,其中,所述直径为所述被覆盖区域内的两点之间的距离;所述第二感兴趣区域的重心所在的医学图像。例如,所述被覆盖区域的直径可以表示所述被覆盖区域内的两点之间的最大值。
在一个例子中,第二医学图像序列中的第一目标医学图像可以为:第二医学图像序列的被覆盖医学图像中,被覆盖区域的面积最大的医学图像。即,在这个例子中,第一目标医学图像可以是第二医学图像序列中被第二感兴趣区域覆盖的面积最大的医学图像。
在另一个例子中,第二医学图像序列中的第一目标医学图像可以为:在第二医学图像序列的被覆盖医学图像中,被覆盖区域的直径最大的医学图像。
在另一个例子中,第二医学图像序列中的第一目标医学图像可以为:第二感兴趣区 域的重心所在的医学图像。其中,在第二感兴趣区域为规则的几何形状的情况下,第二感兴趣区域的重心即为第二感兴趣区域的几何中心。
在该示例中,通过响应于返回第二感兴趣区域的请求,展示第二医学图像序列中被覆盖区域的面积最大的医学图像,或者展示第二医学图像序列中被覆盖区域的直径最大的医学图像,或者展示第二医学图像序列中第二感兴趣区域的重心所在的医学图像,由此在展示第二医学图像序列的过程中,能够快速返回第二感兴趣区域的关键片层,从而能够方便用户快速查看第二感兴趣区域的关键片层,提高用户再次查看第二感兴趣区域的效率。
在一种可能的实现方式中,在所述确定第一医学图像序列中的第一感兴趣区域之后,所述方法还包括:响应于返回第一感兴趣区域的请求,展示第一医学图像序列的第二目标医学图像,其中,第二目标医学图像的至少一部分属于第一感兴趣区域。在该实现方式中,第二目标医学图像是第一医学图像序列中的医学图像,且第二目标医学图像是被第一感兴趣区域覆盖的医学图像。在该实现方式中,通过响应于返回第一感兴趣区域的请求,展示第一医学图像序列中的第二目标医学图像,由此在展示第一医学图像序列的过程中,能够快速返回第一感兴趣区域,从而能够提高用户再次查看医学图像序列的感兴趣区域的便捷性。
作为该实现方式的一个示例,所述第二目标医学图像为以下任意一个医学图像:在所述第一医学图像序列的被覆盖医学图像中,被覆盖区域的面积最大的医学图像,其中,所述被覆盖医学图像表示所述第一医学图像序列中、至少部分区域属于所述第一感兴趣区域的医学图像,所述被覆盖区域表示所述被覆盖医学图像中属于所述第一感兴趣区域的区域;在所述被覆盖医学图像中,被覆盖区域的直径最大的医学图像,其中,所述被覆盖区域的直径表示所述被覆盖区域内的两点之间的最大值;所述第一感兴趣区域的重心所在的医学图像。在该示例中,通过响应于返回第一感兴趣区域的请求,展示第一医学图像序列中被覆盖区域的面积最大的医学图像,或者展示第一医学图像序列中被覆盖区域的直径最大的医学图像,或者展示第一医学图像序列中第一感兴趣区域的重心所在的医学图像,由此在展示第一医学图像序列的过程中,能够快速返回第一感兴趣区域的关键片层,从而能够方便用户快速查看第一感兴趣区域的关键片层,提高用户再次查看第一感兴趣区域的效率。
在一种可能的实现方式中,在所述确定与所述第一感兴趣区域对应的第二感兴趣区域之后,所述方法还包括:统计所述第二感兴趣区域对应的密度信息;展示所述第二感兴趣区域对应的密度信息。在该实现方式中,统计第二感兴趣区域对应的密度信息,可以包括统计第二感兴趣区域内的密度信息。其中,第二感兴趣区域内的密度信息可以包括第二感兴趣区域内的密度的平均值、最大值、最小值、方差、标准差等中的至少之一。其中,医学图像的像素值可以体现医学图像对应的组织的密度信息。例如,CT图像的CT值(即HU值)可以体现CT图像对应的组织的密度信息。相应地,第二感兴趣区域内像素的像素值可以体现第二感兴趣区域包含的组织的密度信息。在该实现方式中,通过自动统计第二感兴趣区域对应的密度信息,并展示第二感兴趣区域对应的密度信息,由此能够实现第二感兴趣区域内的密度的自动分析,从而能够帮助用户快速分析第二感兴趣区域。
作为该实现方式的一个示例,所述展示所述第二感兴趣区域对应的密度信息,可以包括:展示第二感兴趣区域内的密度信息。例如,可以展示第二感兴趣区域内的密度的平均值。
作为该实现方式的一个示例,所述统计所述第二感兴趣区域对应的密度信息,包括:统计所述第二感兴趣区域内的密度信息,以及与所述第二感兴趣区域对应的至少一个第 三感兴趣区域内的密度信息,其中,所述至少一个第三感兴趣区域所在的医学图像序列与所述第二医学图像序列属于不同期相;所述展示所述第二感兴趣区域对应的密度信息,包括:根据所述第二感兴趣区域内的密度信息,以及所述至少一个第三感兴趣区域内的密度信息,展示所述第二感兴趣区域对应的时间密度曲线,其中,所述第二感兴趣区域对应的时间密度曲线表示所述第二感兴趣区域内的组织的密度信息随时间变化的曲线。
在该示例中,统计第二感兴趣区域对应的密度信息还可以包括统计与第二感兴趣区域对应的至少一个第三感兴趣区域内的密度信息。其中,第三感兴趣区域所在的医学图像序列和第二医学图像序列为同一目标对象的医学图像序列。另外,第三感兴趣区域所在的医学图像序列和第二医学图像序列还可以是包含同一目标对象的同一器官或部位的医学图像。例如,第三感兴趣区域所在的医学图像序列和第二医学图像序列是同一个人的肝脏的医学图像序列。在第二医学图像序列与第一医学图像序列属于不同期相的情况下,至少一个第三感兴趣区域可以包括第一感兴趣区域,即,某一第三感兴趣区域所在的医学图像序列即为第一医学图像序列。
在该示例中,任意一个第三感兴趣区域内的密度信息,可以包括该第三感兴趣区域内的密度的平均值、最大值、最小值、方差、标准差等中的至少之一。例如,第二感兴趣区域内的密度信息包括第二感兴趣区域内的密度的平均值,第三感兴趣区域内的密度的平均值,那么,第二感兴趣区域对应的时间密度曲线可以表示第二感兴趣区域内的组织的密度的平均值随时间变化的曲线。
在该示例中,通过统计第二感兴趣区域内的密度信息以及与第二感兴趣区域对应的至少一个第三感兴趣区域内的密度信息,并根据第二感兴趣区域内的密度信息以及至少一个第三感兴趣区域内的密度信息,展示第二感兴趣区域对应的时间密度曲线,由此能够提供第二感兴趣区域内的组织的密度随着时间变化的直观信息,从而能够方便用户通过直观展示的时间密度曲线分析感兴趣区域。
在一个例子中,在所述确定与所述第一感兴趣区域对应的第二感兴趣区域之后,所述方法还包括:统计所述第二感兴趣区域附近的第一参考区域内的密度信息,以及与所述第一参考区域对应的至少一个第二参考区域内的密度信息,其中,所述第一参考区域和所述至少一个第二参考区域均属于正常组织,所述至少一个第二参考区域所在的医学图像序列与所述第二医学图像序列属于不同期相;根据所述第一参考区域内的密度信息,以及所述至少一个第二参考区域内的密度信息,展示所述第一参考区域对应的时间密度曲线,其中,所述第一参考区域对应的时间密度曲线表示所述第一参考区域内的组织的密度信息随时间变化的曲线。
在这个例子中,第一参考区域是第二医学图像序列中、在第二感兴趣区域附近的正常组织区域。其中,第一参考区域可以是用户选择的,也可以是自动选择的,在此不做限定。第一参考区域内的密度信息,可以包括第一参考区域内的密度的平均值、最大值、最小值、方差、标准差等中的至少之一;第二参考区域内的密度信息,可以包括第二参考区域内的密度的平均值、最大值、最小值、方差、标准差等中的至少之一。例如,第一参考区域内的密度信息包括第一参考区域内的密度的平均值,第二参考区域内的密度信息包括第二参考区域内的密度的平均值,那么,第一参考区域对应的时间密度曲线可以表示第一参考区域内的正常组织的密度的平均值随时间变化的曲线。
在这个例子中,通过统计第二感兴趣区域附近的第一参考区域内的密度信息,以及与第一参考区域对应的至少一个第二参考区域内的密度信息,并根据第一参考区域内的密度信息,以及至少一个第二参考区域内的密度信息,展示第一参考区域对应的时间密度曲线,由此能够提供感兴趣区域附近的正常组织区域的密度随着时间变化的直观信息,能够方便用户比对感兴趣区域与正常组织区域。
在一种可能的实现方式中,在所述确定与所述第一感兴趣区域对应的第二感兴趣区域之后,所述方法还可以包括:响应于第二感兴趣区域内的第一位置和第二感兴趣区域外的第二位置被选择,确定第一位置的密度信息和第二位置的密度信息;展示第一位置的密度信息和第二位置的密度信息的对比结果。根据该实现方式,能够方便用户进行单点的密度比对分析。
在一种可能的实现方式中,在所述确定第一医学图像序列中的第一感兴趣区域之后,所述方法还可以包括:在展示第一医学图像序列的过程中,显示第一感兴趣区域的体积的大小。
在一种可能的实现方式中,在所述确定第一医学图像序列中的第一感兴趣区域之后,所述方法还可以包括:在展示第一医学图像序列的过程中,显示第一感兴趣区域的最长径的大小和最短径的大小。
在一种可能的实现方式中,在所述确定与所述第一感兴趣区域对应的第二感兴趣区域之后,所述方法还可以包括:在展示第二医学图像序列的过程中,显示第二感兴趣区域的体积的大小。
在一种可能的实现方式中,在所述确定与所述第一感兴趣区域对应的第二感兴趣区域之后,所述方法还可以包括:在展示第二医学图像序列的过程中,显示第二感兴趣区域的最长径的大小和最短径的大小。
下面通过一个具体的应用场景说明本公开实施例提供的医学图像的展示方法。在该应用场景中,第一医学图像序列属于CT模态、门静脉期,第二医学图像序列的数量为7个,分别属于CT模态、平扫期,CT模态、动脉期,CT模态、门脉延迟期,MRI模态、T1期,MRI模态、T2期,MRI模态、FLAIR期,MRI模态、DWI期。
图2示出本公开实施例的一种应用场景中确定第一医学图像序列中的第一感兴趣区域的示意图。在图2所示的示例中,第一医学图像序列包括83个医学图像,当前展示的是第24个医学图像。可以响应于检测到鼠标右键点击该医学图像的任意位置,弹出“选择VOI”的选项,并可以响应于该“选择VOI”的选项被选择,将鼠标右键单击的位置确定为感兴趣位置,并可以基于该感兴趣位置进行肿瘤的三维分割,得到第一感兴趣区域。
在确定第一感兴趣区域之后,可以在7个第二医学图像序列中分别确定与第一感兴趣区域对应的第二感兴趣区域。在各个第二医学图像序列中分别确定第二感兴趣区域之后,可以在同一界面中展示标记第一感兴趣区域后的第一医学图像序列和标记第二感兴趣区域后的第二医学图像序列。
图3示出本公开实施例的一种应用场景中在同一界面中展示标记感兴趣区域后的不同期相的医学图像序列的示意图。在图3所示的示例中,通过虚线的圆形框标记感兴趣区域。如图3所示,可以在同一界面中,通过不同窗口展示标记感兴趣区域后的平扫期、动脉期、门静脉期和门脉延迟期的医学图像序列。
在一种可能的实现方式中,可以响应于返回感兴趣区域的请求,展示医学图像序列中的目标医学图像。例如,可以响应于返回第一医学图像序列的第一感兴趣区域的请求,展示第一医学图像序列中的第二目标医学图像。如图3所示,可以响应于返回门静脉期的医学图像序列的感兴趣区域的请求,展示门静脉期的医学图像序列中的第二目标医学图像。又如,可以响应于返回第二医学图像序列的第二感兴趣区域的请求,展示第二医学图像序列中的第一目标医学图像。如图3所示,可以响应于返回第二医学图像序列的第二感兴趣区域的请求,展示平扫期、动脉期和门脉延迟期的医学图像序列中的第一目标医学图像。又如,可以响应于返回感兴趣区域的请求,展示界面中的各个医学图像序列中的目标医学图像。如图3所示,可以响应于返回感兴趣区域的请求,展示平扫期、 动脉期、门静脉期和门脉延迟期的医学图像序列中的目标医学图像,由此能够一键跳转至各个医学图像序列的感兴趣区域。
图4示出本公开实施例的一种应用场景中在同一界面中展示标记感兴趣区域后的不同模态的医学图像序列的示意图。在图4所示的示例中,通过实线的方形框标记感兴趣区域。如图4所示,可以在同一界面中,通过不同窗口展示标记感兴趣区域后的不同模态的医学图像序列。其中,左侧窗口中的医学图像序列属于CT模态、门静脉期,右侧窗口中的医学图像序列属于MRI模态、DWI期。
图5示出本公开实施例的一种应用场景中展示感兴趣区域的信息的示意图。如图5所示,可以展示感兴趣区域的位置、体积、长短径、密度、标准差、分割期相等信息。
图6示出本公开实施例的一种应用场景中展示时间密度曲线的示意图。如图6所示,可以展示感兴趣区域对应的时间密度曲线和正常组织(即参考区域)对应的时间密度曲线,以供用户对比。
可以理解,本公开提及的上述各个方法实施例,在不违背原理逻辑的情况下,均可以彼此相互结合形成结合后的实施例,限于篇幅,本公开不再赘述。本领域技术人员可以理解,在具体实施方式的上述方法中,各步骤的具体执行顺序应当以其功能和可能的内在逻辑确定。
此外,本公开还提供了医学图像的展示装置、电子设备、计算机可读存储介质、程序,上述均可用来实现本公开提供的任一种医学图像的展示方法,相应技术方案和技术效果可参见方法部分的相应记载,不再赘述。
图7示出本公开实施例提供的医学图像的展示装置的结构示意图。如图7所示,所述医学图像的展示装置包括:
第一确定模块71,配置为确定第一医学图像序列中的第一感兴趣区域;
第二确定模块72,配置为在至少一个第二医学图像序列中,确定与所述第一感兴趣区域对应的第二感兴趣区域,其中,所述第二医学图像序列和所述第一医学图像序列为同一目标对象的医学图像序列,且所述第二医学图像序列与所述第一医学图像序列属于不同模态或者不同期相;
第一展示模块73,配置为展示标记所述第二感兴趣区域后的第二医学图像序列。
在一种可能的实现方式中,所述装置还包括:
第二展示模块,配置为响应于返回所述第二感兴趣区域的请求,展示所述第二医学图像序列中的第一目标医学图像,其中,所述第一目标医学图像的至少部分区域属于所述第二感兴趣区域。
在一种可能的实现方式中,所述第一目标医学图像为以下任意一个医学图像:
在所述第二医学图像序列的被覆盖医学图像中,被覆盖区域的面积最大的医学图像,其中,所述被覆盖医学图像表示所述第二医学图像序列中、至少部分区域属于所述第二感兴趣区域的医学图像,所述被覆盖区域表示所述被覆盖医学图像中属于所述第二感兴趣区域的区域;
在所述被覆盖医学图像中,被覆盖区域的直径最大的医学图像,其中,所述直径为所述被覆盖区域内的两点之间的距离;
所述第二感兴趣区域的重心所在的医学图像。
在一种可能的实现方式中,所述第一展示模块73配置为:
响应于同时展示第一医学图像序列和第二医学图像序列的请求,在第一窗口中展示标记所述第一感兴趣区域后的第一医学图像序列,并在第二窗口中展示标记所述第二感兴趣区域后的第二医学图像序列。
在一种可能的实现方式中,所述装置还包括:
第一统计模块,配置为统计所述第二感兴趣区域对应的密度信息;
第三展示模块,配置为展示所述第二感兴趣区域对应的密度信息。
在一种可能的实现方式中,
所述第一统计模块配置为:统计所述第二感兴趣区域内的密度信息,以及与所述第二感兴趣区域对应的至少一个第三感兴趣区域内的密度信息,其中,所述至少一个第三感兴趣区域所在的医学图像序列与所述第二医学图像序列属于不同期相;
所述第三展示模块配置为:根据所述第二感兴趣区域内的密度信息,以及所述至少一个第三感兴趣区域内的密度信息,展示所述第二感兴趣区域对应的时间密度曲线,其中,所述第二感兴趣区域对应的时间密度曲线表示所述第二感兴趣区域内的组织的密度信息随时间变化的曲线。
在一种可能的实现方式中,所述装置还包括:
第二统计模块,配置为统计所述第二感兴趣区域附近的第一参考区域内的密度信息,以及与所述第一参考区域对应的至少一个第二参考区域内的密度信息,其中,所述第一参考区域和所述至少一个第二参考区域均属于正常组织,所述至少一个第二参考区域所在的医学图像序列与所述第二医学图像序列属于不同期相;
第四展示模块,配置为根据所述第一参考区域内的密度信息,以及所述至少一个第二参考区域内的密度信息,展示所述第一参考区域对应的时间密度曲线,其中,所述第一参考区域对应的时间密度曲线表示所述第一参考区域内的组织的密度信息随时间变化的曲线。
在一种可能的实现方式中,所述第一确定模块71配置为:
响应于针对所述第一医学图像序列中的任意一个医学图像的任意位置的选择操作,确定感兴趣位置;
基于所述感兴趣位置进行预设类型的三维分割,得到所述第一医学图像序列中的第一感兴趣区域。
在一种可能的实现方式中,所述第一确定模块71配置为:
对第一医学图像序列进行预设类型的三维分割,得到所述第一医学图像序列中的第一感兴趣区域。
在一种可能的实现方式中,所述第二确定模块72配置为:
确定所述第一感兴趣区域的重心的位置,以及所述第一感兴趣区域的重心至所述第一感兴趣区域的边界的最大距离;
根据所述第一感兴趣区域的重心的位置,以及所述第一感兴趣区域的重心至所述第一感兴趣区域的边界的最大距离,在至少一个第二医学图像序列中,确定与所述第一感兴趣区域对应的第二感兴趣区域。
在本公开实施例中,通过确定第一医学图像序列中的第一感兴趣区域,在至少一个第二医学图像序列中,确定与第一感兴趣区域对应的第二感兴趣区域,其中,第二医学图像序列和第一医学图像序列为同一目标对象的医学图像序列,且第二医学图像序列与第一医学图像序列属于不同模态或者不同期相,并展示标记第二感兴趣区域后的第二医学图像序列,由此能够自动确定并展示不同模态或者不同期相的医学图像序列中相应的感兴趣区域,无需用户在不同模态或者不同期相的多个医学图像序列中分别手动标记感兴趣区域,且无需用户对多个医学图像序列中的感兴趣区域进行手动配准,能够降低用户分析不同模态或者不同期相的多个医学图像序列的操作繁琐度和操作难度,节省用户时间,方便用户快速阅片,并能够减小在不同模态或者不同期相的多个医学图像序列中所确定的感兴趣区域的误差,即,能够实现在不同模态或者不同期相的多个医学图像序列中的感兴趣区域的精准分析。
在一些实施例中,本公开实施例提供的装置具有的功能或包含的模块可以用于执行上文方法实施例描述的方法,其具体实现和技术效果可以参照上文方法实施例的描述,为了简洁,这里不再赘述。
本公开实施例还提供一种计算机可读存储介质,其上存储有计算机程序指令,所述计算机程序指令被处理器执行时实现上述方法。其中,所述计算机可读存储介质可以是非易失性计算机可读存储介质,或者可以是易失性计算机可读存储介质。
本公开实施例还提出一种计算机程序,包括计算机可读代码,当所述计算机可读代码在电子设备中运行时,所述电子设备中的处理器执行实现上述方法。
本公开实施例还提供了一种计算机程序产品,配置为存储计算机可读指令,指令被执行时使得计算机执行上述任一实施例提供的医学图像的展示方法的操作。
本公开实施例还提供一种电子设备,包括:一个或多个处理器;配置为存储可执行指令的存储器;其中,所述一个或多个处理器被配置为调用所述存储器存储的可执行指令,以执行上述方法。
电子设备可以被提供为终端、服务器或其它形态的设备。
图8示出本公开实施例提供的一种电子设备800的结构示意图。例如,电子设备800可以是移动电话,计算机,数字广播终端,消息收发设备,游戏控制台,平板设备,医疗设备,健身设备,个人数字助理等终端。
参照图8,电子设备800可以包括以下一个或多个组件:处理组件802,存储器804,电源组件806,多媒体组件808,音频组件810,输入/输出(I/O)的接口812,传感器组件814,以及通信组件816。
处理组件802通常控制电子设备800的整体操作,诸如与显示,电话呼叫,数据通信,相机操作和记录操作相关联的操作。处理组件802可以包括一个或多个处理器820来执行指令,以完成上述的方法的全部或部分步骤。此外,处理组件802可以包括一个或多个模块,便于处理组件802和其他组件之间的交互。例如,处理组件802可以包括多媒体模块,以方便多媒体组件808和处理组件802之间的交互。
存储器804被配置为存储各种类型的数据以支持在电子设备800的操作。这些数据的示例包括配置为在电子设备800上操作的任何应用程序或方法的指令,联系人数据,电话簿数据,消息,图片,视频等。存储器804可以由任何类型的易失性或非易失性存储设备或者它们的组合实现,如静态随机存取存储器(SRAM),电可擦除可编程只读存储器(EEPROM),可擦除可编程只读存储器(EPROM),可编程只读存储器(PROM),只读存储器(ROM),磁存储器,快闪存储器,磁盘或光盘。
电源组件806为电子设备800的各种组件提供电力。电源组件806可以包括电源管理***,一个或多个电源,及其他与为电子设备800生成、管理和分配电力相关联的组件。
多媒体组件808包括在所述电子设备800和用户之间的提供一个输出接口的屏幕。在一些实施例中,屏幕可以包括液晶显示器(LCD)和触摸面板(TP)。如果屏幕包括触摸面板,屏幕可以被实现为触摸屏,以接收来自用户的输入信号。触摸面板包括一个或多个触摸传感器以感测触摸、滑动和触摸面板上的手势。所述触摸传感器可以不仅感测触摸或滑动动作的边界,而且还检测与所述触摸或滑动操作相关的持续时间和压力。在一些实施例中,多媒体组件808包括一个前置摄像头和/或后置摄像头。当电子设备800处于操作模式,如拍摄模式或视频模式时,前置摄像头和/或后置摄像头可以接收外部的多媒体数据。每个前置摄像头和后置摄像头可以是一个固定的光学透镜***或具有焦距和光学变焦能力。
音频组件810被配置为输出和/或输入音频信号。例如,音频组件810包括一个麦克 风(MIC),当电子设备800处于操作模式,如呼叫模式、记录模式和语音识别模式时,麦克风被配置为接收外部音频信号。所接收的音频信号可以被进一步存储在存储器804或经由通信组件816发送。在一些实施例中,音频组件810还包括一个扬声器,配置为输出音频信号。
I/O接口812为处理组件802和***接口模块之间提供接口,上述***接口模块可以是键盘,点击轮,按钮等。这些按钮可包括但不限于:主页按钮、音量按钮、启动按钮和锁定按钮。
传感器组件814包括一个或多个传感器,配置为电子设备800提供各个方面的状态评估。例如,传感器组件814可以检测到电子设备800的打开/关闭状态,组件的相对定位,例如所述组件为电子设备800的显示器和小键盘,传感器组件814还可以检测电子设备800或电子设备800一个组件的位置改变,用户与电子设备800接触的存在或不存在,电子设备800方位或加速/减速和电子设备800的温度变化。传感器组件814可以包括接近传感器,被配置用来在没有任何的物理接触时检测附近物体的存在。传感器组件814还可以包括光传感器,如互补金属氧化物半导体(CMOS)或电荷耦合装置(CCD)图像传感器,在成像应用中使用。在一些实施例中,该传感器组件814还可以包括加速度传感器,陀螺仪传感器,磁传感器,压力传感器或温度传感器。
通信组件816被配置为便于电子设备800和其他设备之间有线或无线方式的通信。电子设备800可以接入基于通信标准的无线网络,如无线网络(Wi-Fi)、第二代移动通信技术(2G)、第三代移动通信技术(3G)、***移动通信技术(4G)/通用移动通信技术的长期演进(LTE)、第五代移动通信技术(5G)或它们的组合。在一个示例性实施例中,通信组件816经由广播信道接收来自外部广播管理***的广播信号或广播相关信息。在一个示例性实施例中,所述通信组件816还包括近场通信(NFC)模块,以促进短程通信。例如,在NFC模块可基于射频识别(RFID)技术,红外数据协会(IrDA)技术,超宽带(UWB)技术,蓝牙(BT)技术和其他技术来实现。
在示例性实施例中,电子设备800可以被一个或多个应用专用集成电路(ASIC)、数字信号处理器(DSP)、数字信号处理设备(DSPD)、可编程逻辑器件(PLD)、现场可编程门阵列(FPGA)、控制器、微控制器、微处理器或其他电子元件实现,配置为执行上述方法。
在示例性实施例中,还提供了一种非易失性计算机可读存储介质,例如包括计算机程序指令的存储器804,上述计算机程序指令可由电子设备800的处理器820执行以完成上述方法。
图9示出本公开实施例提供的一种电子设备1900的结构示意图。例如,电子设备1900可以被提供为一服务器。参照图9,电子设备1900包括处理组件1922,其进一步包括一个或多个处理器,以及由存储器1932所代表的存储器资源,配置为存储可由处理组件1922的执行的指令,例如应用程序。存储器1932中存储的应用程序可以包括一个或一个以上的每一个对应于一组指令的模块。此外,处理组件1922被配置为执行指令,以执行上述方法。
电子设备1900还可以包括一个电源组件1926被配置为执行电子设备1900的电源管理,一个有线或无线网络接口1950被配置为将电子设备1900连接到网络,和一个输入输出(I/O)接口1958。电子设备1900可以操作基于存储在存储器1932的操作***,例如微软服务器操作***(Windows ServerTM),苹果公司推出的基于图形用户界面操作***(Mac OS XTM),多用户多进程的计算机操作***(UnixTM),自由和开放原代码的类Unix操作***(LinuxTM),开放原代码的类Unix操作***(FreeBSDTM)或类似。
在示例性实施例中,还提供了一种非易失性计算机可读存储介质,例如包括计算机程序指令的存储器1932,上述计算机程序指令可由电子设备1900的处理组件1922执行以完成上述方法。
本公开可以是***、方法和/或计算机程序产品。计算机程序产品可以包括计算机可读存储介质,其上载有配置为使处理器实现本公开的各个方面的计算机可读程序指令。
计算机可读存储介质可以是可以保持和存储由指令执行设备使用的指令的有形设备。计算机可读存储介质例如可以是――但不限于――电存储设备、磁存储设备、光存储设备、电磁存储设备、半导体存储设备或者上述的任意合适的组合。计算机可读存储介质的更具体的例子(非穷举的列表)包括:便携式计算机盘、硬盘、随机存取存储器(RAM)、只读存储器(ROM)、可擦式可编程只读存储器(EPROM或闪存)、静态随机存取存储器(SRAM)、便携式压缩盘只读存储器(CD-ROM)、数字多功能盘(DVD)、记忆棒、软盘、机械编码设备、例如其上存储有指令的打孔卡或凹槽内凸起结构、以及上述的任意合适的组合。这里所使用的计算机可读存储介质不被解释为瞬时信号本身,诸如无线电波或者其他自由传播的电磁波、通过波导或其他传输媒介传播的电磁波(例如,通过光纤电缆的光脉冲)、或者通过电线传输的电信号。
这里所描述的计算机可读程序指令可以从计算机可读存储介质下载到各个计算/处理设备,或者通过网络、例如因特网、局域网、广域网和/或无线网下载到外部计算机或外部存储设备。网络可以包括铜传输电缆、光纤传输、无线传输、路由器、防火墙、交换机、网关计算机和/或边缘服务器。每个计算/处理设备中的网络适配卡或者网络接口从网络接收计算机可读程序指令,并转发该计算机可读程序指令,以供存储在各个计算/处理设备中的计算机可读存储介质中。
配置为执行本公开操作的计算机程序指令可以是汇编指令、指令集架构(ISA)指令、机器指令、机器相关指令、微代码、固件指令、状态设置数据、或者以一种或多种编程语言的任意组合编写的源代码或目标代码,所述编程语言包括面向对象的编程语言—诸如Smalltalk、C++等,以及常规的过程式编程语言—诸如“C”语言或类似的编程语言。计算机可读程序指令可以完全地在用户计算机上执行、部分地在用户计算机上执行、作为一个独立的软件包执行、部分在用户计算机上部分在远程计算机上执行、或者完全在远程计算机或服务器上执行。在涉及远程计算机的情形中,远程计算机可以通过任意种类的网络—包括局域网(LAN)或广域网(WAN)—连接到用户计算机,或者,可以连接到外部计算机(例如利用因特网服务提供商来通过因特网连接)。在一些实施例中,通过利用计算机可读程序指令的状态信息来个性化定制电子电路,例如可编程逻辑电路、现场可编程门阵列(FPGA)或可编程逻辑阵列(PLA),该电子电路可以执行计算机可读程序指令,从而实现本公开的各个方面。
这里参照根据本公开实施例的方法、装置(***)和计算机程序产品的流程图和/或框图描述了本公开的各个方面。应当理解,流程图和/或框图的每个方框以及流程图和/或框图中各方框的组合,都可以由计算机可读程序指令实现。
这些计算机可读程序指令可以提供给通用计算机、专用计算机或其它可编程数据处理装置的处理器,从而生产出一种机器,使得这些指令在通过计算机或其它可编程数据处理装置的处理器执行时,产生了实现流程图和/或框图中的一个或多个方框中规定的功能/动作的装置。也可以把这些计算机可读程序指令存储在计算机可读存储介质中,这些指令使得计算机、可编程数据处理装置和/或其他设备以特定方式工作,从而,存储有指令的计算机可读介质则包括一个制造品,其包括实现流程图和/或框图中的一个或多个方框中规定的功能/动作的各个方面的指令。
也可以把计算机可读程序指令加载到计算机、其它可编程数据处理装置、或其它设 备上,使得在计算机、其它可编程数据处理装置或其它设备上执行一系列操作步骤,以产生计算机实现的过程,从而使得在计算机、其它可编程数据处理装置、或其它设备上执行的指令实现流程图和/或框图中的一个或多个方框中规定的功能/动作。
附图中的流程图和框图显示了根据本公开的多个实施例的***、方法和计算机程序产品的可能实现的体系架构、功能和操作。在这点上,流程图或框图中的每个方框可以代表一个模块、程序段或指令的一部分,所述模块、程序段或指令的一部分包含一个或多个配置为实现规定的逻辑功能的可执行指令。在有些作为替换的实现中,方框中所标注的功能也可以以不同于附图中所标注的顺序发生。例如,两个连续的方框实际上可以基本并行地执行,它们有时也可以按相反的顺序执行,这依所涉及的功能而定。也要注意的是,框图和/或流程图中的每个方框、以及框图和/或流程图中的方框的组合,可以用执行规定的功能或动作的专用的基于硬件的***来实现,或者可以用专用硬件与计算机指令的组合来实现。
该计算机程序产品可以具体通过硬件、软件或其结合的方式实现。在一个可选实施例中,所述计算机程序产品具体体现为计算机存储介质,在另一个可选实施例中,计算机程序产品具体体现为软件产品,例如软件开发包(Software Development Kit,SDK)等等。
以上已经描述了本公开的各实施例,上述说明是示例性的,并非穷尽性的,并且也不限于所披露的各实施例。在不偏离所说明的各实施例的范围和精神的情况下,对于本技术领域的普通技术人员来说许多修改和变更都是显而易见的。本文中所用术语的选择,旨在最好地解释各实施例的原理、实际应用或对市场中的技术的改进,或者使本技术领域的其它普通技术人员能理解本文披露的各实施例。
工业实用性
本公开实施例提供了医学图像的展示方法及装置、电子设备、存储介质和计算机程序,其中,方法包括:确定第一医学图像序列中的第一感兴趣区域;在至少一个第二医学图像序列中,确定与所述第一感兴趣区域对应的第二感兴趣区域,其中,所述第二医学图像序列和所述第一医学图像序列为同一目标对象的医学图像序列,且所述第二医学图像序列与所述第一医学图像序列属于不同模态或者不同期相;展示标记所述第二感兴趣区域后的第二医学图像序列。根据本公开的实施例的技术方案,能够自动确定并展示不同模态或者不同期相的医学图像序列中相应的感兴趣区域,无需用户在不同模态或者不同期相的多个医学图像序列中分别手动标记感兴趣区域,且无需用户对多个医学图像序列中的感兴趣区域进行手动配准,能够降低用户分析不同模态或者不同期相的多个医学图像序列的操作繁琐度和操作难度,节省用户时间,方便用户快速阅片,并能够减小在不同模态或者不同期相的多个医学图像序列中所确定的感兴趣区域的误差,即,能够实现在不同模态或者不同期相的多个医学图像序列中的感兴趣区域的精准分析。

Claims (14)

  1. 一种医学图像的展示方法,包括:
    确定第一医学图像序列中的第一感兴趣区域;
    在至少一个第二医学图像序列中,确定与所述第一感兴趣区域对应的第二感兴趣区域,其中,所述第二医学图像序列和所述第一医学图像序列为同一目标对象的医学图像序列,且所述第二医学图像序列与所述第一医学图像序列属于不同模态或者不同期相;
    展示标记所述第二感兴趣区域后的第二医学图像序列。
  2. 根据权利要求1所述的方法,其中,在所述确定与所述第一感兴趣区域对应的第二感兴趣区域之后,所述方法还包括:
    响应于返回所述第二感兴趣区域的请求,展示所述第二医学图像序列中的第一目标医学图像,其中,所述第一目标医学图像的至少部分区域属于所述第二感兴趣区域。
  3. 根据权利要求2所述的方法,其中,所述第一目标医学图像为以下任意一个医学图像:
    在所述第二医学图像序列的被覆盖医学图像中,被覆盖区域的面积最大的医学图像,其中,所述被覆盖医学图像表示所述第二医学图像序列中、至少部分区域属于所述第二感兴趣区域的医学图像,所述被覆盖区域表示所述被覆盖医学图像中属于所述第二感兴趣区域的区域;
    在所述被覆盖医学图像中,被覆盖区域的直径最大的医学图像,其中,所述直径为所述被覆盖区域内的两点之间的距离;
    所述第二感兴趣区域的重心所在的医学图像。
  4. 根据权利要求1至3中任意一项所述的方法,其中,所述展示标记所述第二感兴趣区域后的第二医学图像序列,包括:
    响应于同时展示第一医学图像序列和第二医学图像序列的请求,在第一窗口中展示标记所述第一感兴趣区域后的第一医学图像序列,并在第二窗口中展示标记所述第二感兴趣区域后的第二医学图像序列。
  5. 根据权利要求1至4中任意一项所述的方法,其中,在所述确定与所述第一感兴趣区域对应的第二感兴趣区域之后,所述方法还包括:
    统计所述第二感兴趣区域对应的密度信息;
    展示所述第二感兴趣区域对应的密度信息。
  6. 根据权利要求5所述的方法,其中,
    所述统计所述第二感兴趣区域对应的密度信息,包括:统计所述第二感兴趣区域内的密度信息,以及与所述第二感兴趣区域对应的至少一个第三感兴趣区域内的密度信息,其中,所述至少一个第三感兴趣区域所在的医学图像序列与所述第二医学图像序列属于不同期相;
    所述展示所述第二感兴趣区域对应的密度信息,包括:根据所述第二感兴趣区域内的密度信息,以及所述至少一个第三感兴趣区域内的密度信息,展示所述第二感兴趣区域对应的时间密度曲线,其中,所述第二感兴趣区域对应的时间密度曲线表示所述第二感兴趣区域内的组织的密度信息随时间变化的曲线。
  7. 根据权利要求6所述的方法,其中,在所述确定与所述第一感兴趣区域对应的第二感兴趣区域之后,所述方法还包括:
    统计所述第二感兴趣区域附近的第一参考区域内的密度信息,以及与所述第一参考区域对应的至少一个第二参考区域内的密度信息,其中,所述第一参考区域和所述至少一个第二参考区域均属于正常组织,所述至少一个第二参考区域所在的医学图像序列与 所述第二医学图像序列属于不同期相;
    根据所述第一参考区域内的密度信息,以及所述至少一个第二参考区域内的密度信息,展示所述第一参考区域对应的时间密度曲线,其中,所述第一参考区域对应的时间密度曲线表示所述第一参考区域内的组织的密度信息随时间变化的曲线。
  8. 根据权利要求1至7中任意一项所述的方法,其中,所述确定第一医学图像序列中的第一感兴趣区域,包括:
    响应于针对所述第一医学图像序列中的任意一个医学图像的任意位置的选择操作,确定感兴趣位置;
    基于所述感兴趣位置进行预设类型的三维分割,得到所述第一医学图像序列中的第一感兴趣区域。
  9. 根据权利要求1至8中任意一项所述的方法,其中,所述确定第一医学图像序列中的第一感兴趣区域,包括:
    对第一医学图像序列进行预设类型的三维分割,得到所述第一医学图像序列中的第一感兴趣区域。
  10. 根据权利要求1至9中任意一项所述的方法,其中,所述在至少一个第二医学图像序列中,确定与所述第一感兴趣区域对应的第二感兴趣区域,包括:
    确定所述第一感兴趣区域的重心的位置,以及所述第一感兴趣区域的重心至所述第一感兴趣区域的边界的最大距离;
    根据所述第一感兴趣区域的重心的位置,以及所述第一感兴趣区域的重心至所述第一感兴趣区域的边界的最大距离,在至少一个第二医学图像序列中,确定与所述第一感兴趣区域对应的第二感兴趣区域。
  11. 一种医学图像的展示装置,包括:
    第一确定模块,配置为确定第一医学图像序列中的第一感兴趣区域;
    第二确定模块,配置为在至少一个第二医学图像序列中,确定与所述第一感兴趣区域对应的第二感兴趣区域,其中,所述第二医学图像序列和所述第一医学图像序列为同一目标对象的医学图像序列,且所述第二医学图像序列与所述第一医学图像序列属于不同模态或者不同期相;
    第一展示模块,配置为展示标记所述第二感兴趣区域后的第二医学图像序列。
  12. 一种电子设备,包括:
    一个或多个处理器;
    配置为存储可执行指令的存储器;
    其中,所述一个或多个处理器被配置为调用所述存储器存储的可执行指令,以执行权利要求1至10中任意一项所述的方法。
  13. 一种计算机可读存储介质,其上存储有计算机程序指令,所述计算机程序指令被处理器执行时实现权利要求1至10中任意一项所述的方法。
  14. 一种计算机程序,包括计算机可读代码,当所述计算机可读代码在电子设备中运行时,所述电子设备中的处理器执行实现权利要求1至10中任意一项所述的方法。
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