WO2022218213A1 - Pulse switching signal generating circuit and pulse generating device - Google Patents

Pulse switching signal generating circuit and pulse generating device Download PDF

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Publication number
WO2022218213A1
WO2022218213A1 PCT/CN2022/085712 CN2022085712W WO2022218213A1 WO 2022218213 A1 WO2022218213 A1 WO 2022218213A1 CN 2022085712 W CN2022085712 W CN 2022085712W WO 2022218213 A1 WO2022218213 A1 WO 2022218213A1
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WO
WIPO (PCT)
Prior art keywords
circuit
pulse
voltage
switch
power supply
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Application number
PCT/CN2022/085712
Other languages
French (fr)
Chinese (zh)
Inventor
史世江
王坤
高国庆
王永胜
Original Assignee
杭州德诺电生理医疗科技有限公司
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Publication of WO2022218213A1 publication Critical patent/WO2022218213A1/en

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Classifications

    • H—ELECTRICITY
    • H03—ELECTRONIC CIRCUITRY
    • H03K—PULSE TECHNIQUE
    • H03K3/00—Circuits for generating electric pulses; Monostable, bistable or multistable circuits
    • H03K3/02—Generators characterised by the type of circuit or by the means used for producing pulses
    • H—ELECTRICITY
    • H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02M—APPARATUS FOR CONVERSION BETWEEN AC AND AC, BETWEEN AC AND DC, OR BETWEEN DC AND DC, AND FOR USE WITH MAINS OR SIMILAR POWER SUPPLY SYSTEMS; CONVERSION OF DC OR AC INPUT POWER INTO SURGE OUTPUT POWER; CONTROL OR REGULATION THEREOF
    • H02M7/00—Conversion of ac power input into dc power output; Conversion of dc power input into ac power output
    • H02M7/02—Conversion of ac power input into dc power output without possibility of reversal
    • H02M7/04—Conversion of ac power input into dc power output without possibility of reversal by static converters

Definitions

  • the present application relates to the field of medical devices, in particular to a pulse switch signal generating circuit and a pulse generating device.
  • An object of the present application is to propose a pulse switch signal generating circuit capable of generating high-voltage pulses to act on biological tissues.
  • the present application provides a pulse switch signal generating circuit, comprising:
  • the switch circuit outputs a pulse switch signal by switching on and off;
  • the drive circuit has a pulse signal input end, a power supply end and a drive end; the drive end is connected to the controlled end of the switch circuit for controlling the on-off of the switch circuit;
  • a pulse control circuit connected to the pulse signal input end of the drive circuit, and the pulse control circuit is used for outputting the pulse control signal
  • a drive power supply circuit the output end of the drive power supply circuit is connected with the power supply end of the drive circuit.
  • the pulse control circuit includes a frequency generator, and the frequency generator sends out at least one pulse control signal according to preset parameters.
  • the pulse control circuit further includes a main controller, and the main controller is electrically connected to the frequency generator to send the preset parameters to the frequency generator, and the preset parameters are sent to the frequency generator.
  • the set parameters include at least one of adjustable pulse frequency, pulse number and duty cycle.
  • the main controller further includes a counting circuit, and the counting circuit is electrically connected to the output end of the frequency generator for detecting the number of pulses output by the frequency generator.
  • the pulse switch signal generating circuit has a human-computer interaction component; the human-computer interaction component is used to receive an adjustment signal, and the adjustment signal is used to control the number of pulses, the number of pulses of the pulse signal, and the number of pulses. at least one of frequency and duty cycle is adjusted.
  • the pulse switch signal generating circuit further includes an optical fiber communication circuit, and the optical fiber communication circuit is configured to send the pulse control signal in the form of light energy to the pulse signal input end of the drive circuit.
  • the driving power supply circuit includes a transformer device and a rectifier circuit connected in series in sequence, the primary side of the transformer device is connected to the AC power supply, and the secondary side is connected to the rectifier circuit, and the rectifier circuit The output end is connected to the power end of the drive circuit.
  • the transformer device includes a current transformer, the primary winding of the current transformer is connected to the AC power source, the secondary winding of the current transformer outputs an AC voltage, and is connected to the rectifier circuit electrical connection.
  • the drive power supply circuit further includes an inverter circuit, an input end of the inverter circuit is connected to a DC power supply, and an output end of the inverter circuit is connected to the primary winding of the current transformer.
  • the drive power supply circuit further includes a voltage adjustment circuit, and the voltage adjustment circuit is connected to the output end of the rectifier circuit, so as to convert the DC power output by the rectifier circuit to DC to generate the first voltage and the second voltage;
  • the first voltage is connected to the power supply terminal of the driving circuit
  • the second voltage is connected to the pulse signal input end of the driving circuit through a pull-up resistor.
  • the switch circuit includes a switch tube
  • the switch circuit further includes a discharge circuit, and the discharge circuit is connected between the controlled end and the second end of the switch tube; wherein, the first end of the switch tube is supplied with high-voltage power input, and the switch The second end of the tube is for outputting high-voltage electrical energy.
  • the switch circuit further includes a voltage divider circuit, and the voltage divider circuit has a power input end and a voltage divider output end;
  • the power input end of the voltage divider circuit is connected to a third power source, and the voltage divider output end is connected to the second end of the switch tube, so that the driving voltage on the controlled end of the switch tube is lower than the first voltage, the voltage difference between the controlled end and the second end of the switch tube is a negative voltage.
  • the voltage dividing circuit includes a voltage dividing resistor and a Zener diode
  • the anode of the zener diode is grounded; the first end of the voltage divider is the power input end, and the second end of the voltage divider is connected to the cathode of the zener diode to form the voltage divider output.
  • the switch circuit includes one or more switch tubes connected in series or in parallel; there are one or more of the drive circuits, and each of the drive circuits correspondingly drives and controls one or more of the drive circuits. On-off of the switch tube.
  • one or more driving power supply circuits there are one or more driving power supply circuits, and one driving power supply circuit correspondingly provides power for one or more of the driving circuits.
  • the pulse control circuit sends out one or more pulse control signals, and one of the pulse control signals is correspondingly output to one or more pulse signal input terminals of the drive circuit.
  • each current transformer there are one or more current transformers, and when there are multiple current transformers, the primary windings of each current transformer are sequentially connected in series with the AC power supply, and each The secondary windings of each of the current transformers are respectively connected to the rectifier circuit.
  • the numbers of the rectifier circuits, the driving circuits and the switching circuits are all equal to the number of the current transformers.
  • the primary windings of each of the current transformers are connected in series with the AC power source in sequence, and the secondary windings of each of the current transformers are respectively connected to a corresponding rectifier circuit through a corresponding rectifier circuit.
  • the drive circuit is powered;
  • One or more of the switch circuits are connected in series or in parallel, and each of the drive circuits is connected to a corresponding one of the switch circuits for controlling the on-off of the corresponding one of the switch circuits.
  • the pulse switch signal generating circuit further includes a transmission line, and the transmission line is connected in series with the primary windings of the multiple current transformers; the voltage level of the transmission line is greater than or equal to 20KV.
  • the present application also proposes a pulse generating device, including a high-voltage power supply unit and the pulse switch signal generating circuit;
  • the switch circuit of the pulse switch signal generating circuit, the high-voltage power supply unit and the load form a series loop, and the switch circuit acts on the load by generating high-voltage pulses through on-off switching.
  • the high-voltage power supply unit includes a high-voltage DC power supply and an energy storage capacitor electrically connected to the high-voltage DC power supply; the energy storage capacitor forms a series loop with the switch circuit and the load;
  • the energy storage capacitor is used for storing the output electric energy of the high voltage direct current power supply, and provides a pulse voltage to the load through the switch circuit.
  • the pulse switch signal generating circuit of the solution of the present application includes a switch circuit, a drive circuit, a pulse control circuit, and a drive power supply circuit.
  • the switch circuit is connected in series between the high-voltage power supply and the biological tissue, so that the switch circuit generates high-voltage pulses on the biological tissue through on-off switching under the driving of the driving circuit.
  • the drive power supply circuit provides power for the drive circuit; the pulse control circuit is used for outputting a pulse control signal, so that the drive circuit outputs a drive signal according to the pulse control signal.
  • the solution of the present application can generate high-voltage pulses to act on biological tissues, form irreversible electroporation on the cell membrane, change the permeability of the cell membrane, cause cell death, and completely ablate biological tissues more accurately; and through high-voltage pulse ablation, It will not cause irreversible damage to other important tissues in the ablation area, thereby reducing the complications associated with other traditional ablation methods. Therefore, when the high-voltage pulse generated by the solution of this embodiment acts on the biological tissue, the effectiveness of ablation can be improved. And because the control signal of the drive circuit is derived from the pulse control circuit, and the power supply of the drive circuit is derived from the drive power supply circuit, the mutual interference between power supply and control can be effectively avoided, and the operational reliability of the drive circuit can be improved.
  • FIG. 1 is a circuit connection block diagram of a pulse switch signal generating circuit, a load, and a high-voltage power supply unit according to an embodiment.
  • Fig. 2 is a circuit connection block diagram of a pulse switch signal generating circuit, a load, and a high-voltage power supply unit according to another embodiment.
  • Fig. 3 is a circuit connection block diagram of a pulse generating device, a power grid, and a load according to an embodiment.
  • FIG. 4 is a circuit diagram of a drive circuit and a switch circuit of a pulse switch signal generating circuit according to an embodiment.
  • FIG. 5 is a partial circuit diagram illustrating a driving power supply circuit of a pulse switching signal generating circuit according to an embodiment.
  • FIG. 6 is a partial circuit structure block diagram of a pulse switch signal generating circuit according to another embodiment.
  • directional indications (such as up, down, left, right, front and rear) are used to explain the structure and movement of various elements of the present application not absolute but relative. These descriptions are appropriate when the elements are in the positions shown in the drawings. If the description of the positions of these elements changes, the indications of these directions change accordingly.
  • Example embodiments will now be described more fully with reference to the accompanying drawings.
  • Example embodiments can be embodied in various forms and should not be construed as limited to the examples set forth herein; rather, these example embodiments are provided so that the description of this application will be thorough and complete, and will convey the concepts of the example embodiments It will be fully conveyed to those skilled in the art.
  • the drawings are merely schematic illustrations of the present application and are not necessarily drawn to scale.
  • the same reference numerals in the drawings denote the same or similar parts, and thus their repeated descriptions will be omitted.
  • FIG. 1 is a circuit connection block diagram of a pulse switch signal generating circuit 1 , a load 3 , and a high-voltage power supply unit 2 according to an embodiment.
  • the present application first proposes a pulse switch signal generating circuit 1 for a pulse generating device.
  • the pulse switch signal generating circuit 1 includes a switch circuit 11 , a drive circuit 12 , a pulse control circuit 13 and a drive power supply circuit 14 .
  • the switch circuit 11 is connected in series between the high-voltage power supply unit 2 and the load 3 to output a pulse switch signal by switching on and off, thereby generating a high-voltage pulse on the load 3 .
  • the load 3 here can be biological tissue to be ablated.
  • the driving circuit 12 has a pulse signal input terminal, a power supply terminal and a driving terminal; the driving terminal is connected to the controlled terminal of the switching circuit 11 for controlling the on-off of the switching circuit 11; the pulse signal input of the pulse control circuit 13 and the driving circuit 12 The pulse control circuit 13 is used for outputting the pulse control signal; the output terminal of the driving power supply circuit 14 is connected to the power supply terminal of the driving circuit 12 .
  • the pulse control circuit 13 provides the driving circuit 12 with a pulse control signal
  • the driving power supply circuit 14 provides power for the driving circuit 12, so that the driving circuit 12 can output the driving signal for controlling the on-off of the switch circuit 11.
  • the output of the high-voltage power supply unit 2 is controlled by the on-off of the switch circuit 11 , and a high-voltage pulse is generated on the load 3 .
  • a high-voltage pulse can be generated to form irreversible electroporation on the cell membrane, change the permeability of the cell membrane, cause cell death, and completely ablate biological tissue more accurately; and through high-voltage pulse ablation, It will not cause irreversible damage to other important tissues other than the target tissue in the ablation area, thereby reducing the complications associated with other traditional ablation methods. Therefore, when the high-voltage pulse generated by the solution of this embodiment acts on the biological tissue, the effectiveness of ablation can be improved.
  • control signal of the drive circuit 12 is derived from the pulse control circuit 13 and the power supply of the drive circuit 12 is derived from the drive power supply circuit 14, the mutual interference between power supply and control can be effectively avoided, and the operation reliability of the drive circuit 12 is improved. sex.
  • FIG. 2 is a circuit connection block diagram of a pulse switch signal generating circuit 1 , a load 3 , and a high-voltage power supply unit 2 according to another embodiment.
  • the pulse control circuit 13 includes a frequency generator 131, and the frequency generator 131 sends out at least one pulse control signal according to preset parameters; when the frequency generator 131 sends out two pulse control signals according to the preset parameters :
  • There may be one or two driving circuits 12 which respectively generate two driving signals under the control of two pulse control signals; there are two switching circuits 11 , and the two driving signals correspondingly drive two switching circuits 11 to work.
  • two high-voltage power supply units 2 may be correspondingly provided, and the two high-voltage power supply units 2 are respectively a positive high-voltage power supply and a negative high-voltage power supply. Therefore, by controlling the two switch circuits 11 to be turned on alternately, bipolar high-voltage pulses with alternating positive and negative can be generated on the load 3, and the electric field distribution of the bipolar high-voltage pulses is more uniform, which can reduce muscle contraction, improve the ablation effect, and reduce the Requirements for the switching frequency of the switching circuit 11 .
  • the frequency generator 131 can work independently, and send out the pulse control signal through the parameter control stored in the internal memory.
  • the pulse control circuit 13 further includes a main controller 132 , and the main controller 132 is electrically connected to the frequency generator 131 to send preset parameters to the frequency generator 131 .
  • the parameters include at least one of adjustable pulse frequency, pulse number and duty cycle.
  • the main controller 132 may specifically be an ARM processor, and certainly may be an MCU or a CPU.
  • the main controller 132 sends preset parameters to the frequency generator 131 , and the frequency generator 131 generates pulse control signals according to the preset parameters and sends them to the driving circuit 12 .
  • the main controller 132 automatically generates preset parameters and sends them to the frequency generator 131 according to the current working mode of the pulse generating device. In another example, the main controller 132 generates preset parameters according to a user's adjustment of a specific parameter.
  • the human-computer interaction component can be a key component, a touch screen component, a host computer, or a voice input component. Through the human-computer interaction component, the user can adjust at least one of the pulse frequency, the number of pulses and the duty cycle.
  • the main controller 132 generates preset parameters according to the received adjustment signal and sends them to the frequency generator 131 to make the frequency The pulse control signal issued by the generator 131 changes accordingly.
  • the main controller 132 further includes a counting circuit, which is electrically connected to the output terminal of the frequency generator 131 for detecting the number of pulses output by the frequency generator 131 .
  • the main controller 132 may be a main control chip, and a counting circuit is integrated in the main control chip. The counting circuit counts the number of inversions of the level of the pulse control signal output by the frequency generator 131 .
  • FIG. 3 is a circuit connection block diagram of a pulse generating device, a power grid, and a load according to an embodiment.
  • a display device 5 can also be provided, and optical fiber communication is used between the display device 5 and the main controller 132 and between the main controller 132 and the frequency generator 131 to achieve electrical isolation. , to improve the insulation level of the pulse generating equipment, and reduce the danger of high-voltage electric shock for patients and operators.
  • a first auxiliary power supply circuit 6 may be provided, and the voltage of the grid 4 is input into the first auxiliary power supply circuit 6, and after being processed by the first auxiliary power supply circuit 6, a DC voltage is output, and the DC voltage is used to supply power to the display device 5.
  • FIG. 4 is a circuit diagram of a drive circuit and a switch circuit of a pulse switch signal generating circuit according to an embodiment.
  • the pulse switch signal generating circuit 1 further includes an optical fiber communication circuit 15, and the optical fiber communication circuit 15 is used for sending the pulse control signal in the form of light energy to the pulse signal input end of the driving circuit 12;
  • the optical fiber communication circuit 15 includes: The electro-optical conversion circuit, the transmission circuit and the photoelectric conversion circuit 153 are connected in sequence, wherein: the electro-optical conversion circuit is connected to the pulse control circuit 13 for converting the electrical signal of the pulse control signal into an optical signal; the transmission circuit is used for transmitting the optical signal to the pulse control circuit 13.
  • Photoelectric conversion circuit 153 the photoelectric conversion circuit 153 is used to convert the optical signal into an electrical signal and output it to the pulse signal input end of the driving circuit 12 .
  • the electro-optical conversion circuit may specifically be a light emitting diode, an infrared LED, a laser diode, or the like.
  • the transmission circuit can be an optical fiber, and the photoelectric conversion circuit can be an optocoupler.
  • the driving circuit 12 is a driving chip U2, which has a pulse signal input terminal IN, and the pulse signal input terminal IN is electrically connected to the photoelectric conversion circuit 153 through the first resistor R1, so as to receive the signal converted by the photoelectric conversion circuit 153.
  • the electrical signal of the pulse signal; the pulse signal input terminal IN is grounded through the second resistor R2, and the ground terminal is VCC_0.
  • FIG. 5 is a partial circuit diagram illustrating the driving power supply circuit 14 of the pulse switch signal generating circuit according to an embodiment.
  • the drive power supply circuit 14 includes a transformer device 142 and a rectifier circuit 143 that are connected in series.
  • the primary side of the transformer device 142 is connected to the AC power supply, and the secondary side is connected to the rectifier circuit 143.
  • the output end of the rectifier circuit 143 It is connected to the power supply terminal of the driving circuit 12 .
  • the transformer device 142 has the function of isolating and transforming, and may specifically be a current transformer L or a transformer.
  • the transformer device 142 includes a current transformer L, the primary winding of the current transformer L is connected to an AC power source, and the secondary winding of the current transformer L outputs an AC voltage and is electrically connected to the rectifier circuit 143 .
  • the rectifier circuit 143 may include, but is not limited to, a full-bridge rectifier circuit.
  • the turns ratio of the voltage primary winding and the secondary winding of the current transformer L is between 1:10 and 1:20, specifically 1:14.
  • the rectifier circuit 143 may adopt a diode rectifier circuit.
  • D1, D2, D3, and D4 form the diode rectifier circuit 143
  • the zener diode D5 is used to stabilize the output of the diode rectifier circuit.
  • Capacitor C1 is used to filter out clutter.
  • the drive power supply circuit 14 further includes a voltage adjustment circuit 144, and the voltage adjustment circuit 144 is connected to the output end of the rectification circuit 143, so as to convert the DC power output by the rectification circuit 143 to DC to generate the first voltage VCC1 and the second voltage.
  • VCC2 the first voltage VCC1 is connected to the pulse signal input terminal IN of the driving circuit 12 through the pull-up resistor R3; the second voltage VCC2 is connected to the power supply terminal VDD of the driving circuit 12.
  • the voltage adjustment circuit 144 may be a voltage conversion chip.
  • the first voltage VCC1 is set according to the pull-up voltage required by the pulse input pin of the driving chip.
  • the second voltage VCC2 is set according to the power supply voltage required by the driving circuit 12 .
  • the first voltage is set to 2 ⁇ 8V. Specifically, it can be 5V.
  • the second voltage is set to be 20V-30V, specifically 25V.
  • the set value of the first voltage VCC1 can not only meet the requirements of driving the switch circuit 11 normally, but also can still meet the normal driving of the switch circuit 11 under the premise of setting a reverse turn-off voltage for the switch circuit 11 . It will be illustrated in the following examples.
  • the power supply for the driving circuit 12 is set to pass through the current transformer L, while the pulse control signal does not pass through the current transformer L, so as to isolate the power supply from the pulsed control signal, and provide power for the driving circuit 12. Therefore, the power supply will not be interfered by the harmonics of the pulse control signal, so that the stability of the power supply to the driving circuit 12 can be improved, thereby improving the working stability of the driving circuit 12 and reducing the instability of the power supply of the driving circuit.
  • the output high voltage pulse is unstable.
  • the driving power supply circuit 14 further includes an inverter circuit 141, the input end of the inverter circuit 141 is connected to the DC power supply, and the output end of the inverter circuit 141 is connected to the current transformer L Primary winding connection.
  • the inverter circuit 141 can be constructed by constructing an inverter bridge circuit or using an inverter chip.
  • the turns ratio of the primary winding and the secondary winding of the isolation transformer 21 It can be 1:1, which not only plays the role of isolation, but also meets the voltage requirements of the internal circuit. In other embodiments, the turns ratio of the primary winding and the secondary winding of the isolation transformer 21 can also be adjusted according to actual requirements.
  • the second auxiliary power circuit 145 has two voltage outputs, the first voltage output is about 24V, and the second voltage output is about 15V. The first voltage output is used to power the main controller 132 .
  • the second voltage output is the above-mentioned DC power source, and is used for input to the inverter circuit 141 .
  • the inverter circuit 141 includes a step-up transformer to boost the 15V voltage, and output the AC voltage after boosting and inverting.
  • the voltage value output to the drive power supply circuit 14 can be increased through the boosting process of the inverter circuit 141, and a higher drive power supply voltage can improve the switching speed of the switch tube Q1 in the switch circuit 11 and improve the response speed, thereby The frequency of the high-voltage pulse output by the pulse generating device can be increased.
  • the AC power is generated after the DC power is inverted, so that the stability of the AC power can be improved.
  • the AC power supply further supplies power to the drive circuit 12 through the current transformer L and the rectifier circuit 143 , thus improving the power supply stability of the drive circuit 12 .
  • the switch circuit 11 includes a switch tube Q1; the switch circuit 11 further includes a discharge circuit 16, and the discharge circuit 16 is connected between the controlled end and the second end of the switch tube Q1; wherein , the first end of the switch tube Q1 is input to the positive pole of the high voltage power supply, and the second end of the switch tube Q1 is connected to the negative pole of the high voltage power supply for high voltage power output.
  • the controlled end of the switch tube Q1 is connected to the output end OUT of the driving circuit 12 through a fourth resistor R4.
  • the second end of the switch tube Q1 can be grounded through the capacitor C3, which can provide a low-impedance AC path for the pulse signal driving the switch tube Q1.
  • the switch transistor Q1 may include, but is not limited to, a MOS transistor, a triode or an IGBT. Take NMOS tube as an example.
  • the controlled end corresponds to the gate of the MOS transistor, the first end is the drain, and the second end is the source.
  • the bleeder circuit 16 may include one or more resistors, which may be connected in series or parallel.
  • the discharge circuit 16 includes a fifth resistor R5, and the fifth resistor R5 is connected between the controlled end and the second end of the switching transistor Q1.
  • the fifth resistor R5 can form a discharge loop with the diode in the switch tube to discharge the electric energy in the switch tube Q1, so as to reduce the turn-off loss and damage probability of the switch tube Q1 tube, and improve the high voltage The working reliability of the pulse generating circuit.
  • the switch circuit 11 further includes a voltage divider circuit 17, and the voltage divider circuit 17 has a power input terminal and a voltage divider output terminal; the power source input terminal of the voltage divider circuit 17 is connected to a third power source, and the voltage divider output terminal is connected to the switch tube Q1.
  • the second end of the switch tube Q1 is connected to make the voltage difference between the controlled end and the second end of the switch tube Q1 a negative voltage when the driving voltage on the controlled end of the switch tube Q1 is lower than the first voltage.
  • the voltage divider circuit 17 can be composed of a plurality of resistors in series, or can be composed of a resistor and a zener diode.
  • the voltage dividing circuit 17 includes a voltage dividing resistor R6 and a Zener diode D6; the anode of the Zener diode D6 is grounded; the first end of the voltage dividing resistor R6 is the power input terminal, and the third The two terminals are connected to the cathode of the Zener diode D6 to form a voltage divider output terminal.
  • the power input terminal is connected to the third power source, and the third power source can be set to the above-mentioned second voltage VCC2.
  • Both ends of the voltage dividing resistor R6 can be connected with a second capacitor C2 in parallel, and the second capacitor C2 can filter the peak voltage in the second voltage VCC2 to prevent the voltage of the second voltage VCC2 from causing the voltage of the voltage divider output terminal to become unstable.
  • the frequency response characteristic of the voltage dividing circuit 17 can be improved.
  • the voltage dividing resistor R6 and the zener diode D6 form a voltage dividing circuit 17.
  • a voltage of about 5V can be generated on the zener diode D6.
  • the cathode of the Zener diode D6 is connected to the second terminal of the switch tube Q1, so the voltage on the second terminal of the switch tube Q1 is about 5V, so when the driving voltage output by the driving circuit 12 is lower than the first voltage (eg 5V), The switch tube Q1 will be turned off quickly because the pressure difference between the second end and the controlled end is negative pressure. Therefore, this embodiment can improve the turn-off speed of the switch tube Q1, reduce the turn-off loss and damage probability of the switch tube Q1, and improve the working reliability of the high-voltage pulse generating circuit.
  • At least one freewheeling diode is connected in parallel between the first end and the second end of the switch Q1 .
  • the cathode of the freewheeling diode is connected with the positive pole of the high-voltage power supply, and the anode is connected with the negative pole of the high-voltage power supply.
  • FIG. 6 is a partial circuit structure block diagram of a pulse switch signal generating circuit 1 according to another embodiment.
  • the switch circuit 11 can also be set to include one or more switch tubes Q1 connected in series or in parallel; the drive circuit 12 corresponds to one or more, and each drive circuit 12 correspondingly drives and controls the on-off of one or more switch tubes Q1. break.
  • the switch transistor Q1 can be a silicon carbide MOS transistor.
  • a plurality of silicon carbide MOS tubes are cascaded in parallel or in series, and a large current and high voltage switching circuit 11 is realized by using a plurality of small current and low voltage MOS tubes, which effectively improves the voltage and current of the high voltage pulse output by the output pulse generator. level; and because of the use of a low-current and low-voltage MOS tube, the manufacturing cost can be reduced.
  • one drive power supply circuit 14 and one pulse control signal can be configured.
  • there are a plurality of switch circuits 11 there may be various embodiments corresponding to the configuration of the drive power supply circuit 14 .
  • one driving power supply circuit 14 there are one or more driving power supply circuits 14 , and one driving power supply circuit 14 correspondingly provides power for one or more driving circuits 12 .
  • the plurality of driving power supply circuits 14 are in a one-to-one correspondence to supply power to the plurality of driving circuits 12 . This example can improve the independence of the power supply of each switch circuit 11 , and reduce the power supply interference received by each switch circuit 11 , thereby ensuring the working reliability of the pulse generating device.
  • one drive power supply circuit 14 can also supply power to two or more drive circuits 12 at the same time. This embodiment can reduce the number of drive power supply circuits 14 , which is beneficial to reduce the volume of the pulse generating device. reduce manufacturing cost.
  • the pulse control circuit 13 sends out one or more pulse control signals, and one pulse control signal is outputted to one or more pulse signal input terminals of the driving circuit 12 correspondingly.
  • the plurality of pulse control circuits 13 provide pulse control signals to the plurality of driving circuits 12 in a one-to-one correspondence. This example can improve the controllability of each switch circuit 11 and reduce the interference received by each switch circuit 11 in the process of receiving the pulse control signal, thereby ensuring the working reliability of the pulse generating device.
  • one pulse control circuit 13 may simultaneously provide pulse control signals for two or more driving circuits 12 . This embodiment can improve the working synchronization of the switching circuit 11 , which is beneficial to reduce the volume of the pulse generating device and reduce the production cost.
  • the number of rectifier circuits 143 , driving circuits 12 and switching circuits 11 is set to be the same as that of the current transformers.
  • the number of L is equal.
  • the primary winding of each current transformer L is connected in series with the AC power supply (the output end of the inverter circuit 141 ) in turn, and the secondary winding of each current transformer L is connected in series.
  • a corresponding rectifier circuit 143 respectively supplies power to a corresponding drive circuit 12; one or more switch circuits 11 are connected in series or in parallel, and each drive circuit 12 is connected with a corresponding switch circuit 11 for controlling the corresponding The on-off of a switch circuit 11.
  • FIG. 6 there are six current transformers (L1, L2, L3, L4, L5, L6), and there are six corresponding driving circuits 12 (the first driving circuit 121, the second driving circuit 122, The third driving circuit 123 , the fourth driving circuit 124 , the fifth driving circuit 125 , the sixth driving circuit 126 ), the switch circuits 11 correspond to six (the first switch circuit 111 , the second switch circuit 112 , the third switch circuit 113 ) , the fourth switch circuit 114, the fifth switch circuit 115, the sixth switch circuit 116).
  • the first switch circuit 111 , the second switch circuit 112 , and the third switch circuit 113 , the load 3 and the positive high voltage power supply 201 form a positive high voltage pulse generating circuit.
  • the fourth switch circuit 114 , the fifth switch circuit 115 , and the sixth switch circuit 116 form a negative high voltage pulse generating loop with the load 3 and the negative high voltage power supply 202 .
  • the AC voltage output by each current transformer is rectified by the corresponding rectifier circuit 143 (not shown in FIG. 6 ), and then supplies power to one drive circuit 12 , and one drive circuit 12 is used to drive one switch circuit 11 .
  • FIG. 6 there are two optical fiber communication circuits 15, namely a first optical fiber communication circuit 151 and a second optical fiber communication circuit 152, and the frequency generator 131 generates a first pulse control signal and a second pulse control signal correspondingly.
  • the first pulse control signal is used for input to the pulse signal input terminals of the first driving circuit 121, the second driving circuit 122 and the third driving circuit 123; the second pulse control signal is used for inputting the fourth driving circuit 124, the fifth driving circuit The pulse signal input terminal of the circuit 125 and the sixth driving circuit 126 .
  • the current transformers L have an isolation function, the primary windings of each current transformer L are set in series to be connected to the output end of the inverter circuit 141 in sequence, so as not to cause each current transformer L The secondary windings interfere with each other.
  • the number of inverter circuits 141 can be reduced, which is beneficial to reducing the volume of the pulse generating device.
  • the set pulse switch signal generating circuit 1 further includes a transmission line 18 , and the transmission line 18 is connected in series with the primary windings of a plurality of current transformers L.
  • the peak voltage of the harmonic is 2-3 times the voltage of the pulse signal, and the voltage level of the transmission line can be selected to be greater than or equal to 20KV to improve the reliability of the power supply to the driving circuit 12. sex.
  • the present application further proposes a pulse generating device.
  • the pulse generating device includes a high-voltage power supply unit 2 and a pulse switching signal generating circuit 1; a switching circuit 11 of the pulse switching signal generating circuit 1, a high-voltage power supply unit 2 and a load 3 forms a series loop, and the switch circuit 11 acts on the load 3 by generating high-voltage pulses through on-off switching.
  • the pulse generating device When there is one high-voltage power supply unit 2, the pulse generating device generates unipolar high-voltage pulses correspondingly. When there are two high-voltage power supply units 2, they are positive high-voltage power supply unit and negative high-voltage power supply unit. Bipolar high voltage pulses of positive polarity high voltage pulses and negative polarity high voltage pulses.
  • the high-voltage power supply unit 2 can also be set to include a high-voltage power supply and an energy storage capacitor 23 electrically connected to the high-voltage power supply; the energy storage capacitor 23 forms a series loop with the switch circuit 11 and the load 3; the energy storage capacitor 23 It is used to store the output power of the high-voltage power supply, and provide pulse voltage to the load 3 through the switch circuit 11 .
  • the energy storage capacitor 23 includes a first energy storage capacitor 231 and a second energy storage capacitor 232.
  • the first energy storage capacitor 231 is used to store the DC power output by the positive high voltage power supply 201
  • the second energy storage capacitor 232 is used to store The DC power output by the negative high voltage power supply 202 .
  • the setting of the energy storage capacitor 23 can reduce the requirement for the output power of the high-voltage DC power supply, effectively reduce the volume of the high-voltage DC power supply and reduce the material cost of the whole machine.
  • the isolated DC high voltage circuit 22 includes a step-up transformer, a first rectifier circuit, a second inverter circuit, a second rectifier circuit and a PWM control circuit 221 , wherein the PWM control circuit 221 is connected to the main controller 132 .
  • the step-up ratio of the step-up transformer may be 1:15.
  • the pulse switch signal generating circuit 1 further includes a voltage collection circuit 191 and a current collection circuit 192.
  • the voltage collection circuit 191 is used to collect the voltage of the output high voltage pulse
  • the current collection circuit 192 is used to collect the output high voltage pulse.
  • the voltage acquisition circuit 191 and the current acquisition circuit 192 are respectively connected to the main controller 132. If the voltage monitoring value or the current monitoring value is different from the preset value, the main controller 132 will control the output of the PWM control circuit 221 of the isolated DC high voltage circuit 22.
  • the duty cycle of the PWM signal is used to adjust the output voltage and current of the inverter circuit in the isolated DC high voltage circuit 22 . When the duty cycle of the PWM signal increases, the output voltage and current of the isolated DC high voltage circuit 22 increase. When the duty cycle of the PWM signal decreases, the output voltage and current of the isolated DC high-voltage circuit 22 decrease.
  • pulse switch signal generating circuit and the pulse generating device of the present application may include, but are not limited to, application in the field of medical devices, and may also be applied in other fields.

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Abstract

The present application provides a pulse switching signal generating circuit and a pulse generating device. The pulse switching signal generating circuit (1) comprises a switching circuit (11), a driving circuit (12), and a pulse control circuit (13). The switching circuit (11) is connected in series between a high-voltage power source unit (2) and a load (3) to output a pulse switching signal by means of on/off switching, thereby generating a high-voltage pulse on the load (3). The driving circuit (12) has a pulse signal input end, a power source end, and a driving end. The driving end is connected to a controlled end of the switching circuit (11) to control on/off of the switching circuit (11). The pulse control circuit (13) is connected to the pulse signal input end of the driving circuit (12), and the pulse control circuit (13) is configured to output a pulse control signal. An output end of a driving power supply circuit (14) is connected to the power source end of the driving circuit (12). When acting on biological tissue, the high-voltage pulse generated in the solution of present embodiments can improve the effectiveness of ablation.

Description

脉冲开关信号发生电路与脉冲发生设备Pulse switch signal generating circuit and pulse generating equipment 技术领域technical field
本申请要求于2021年4月15日提交中国专利局、优先权号为CN202110407422.0、申请名称为“脉冲开关信号发生电路与脉冲发生设备”的中国专利申请的优先权，其全部内容通过引用结合在本申请中。This application claims the priority of a Chinese patent application with a priority number of CN202110407422.0 and an application title of "Pulse Switching Signal Generation Circuit and Pulse Generation Equipment" filed with the China Patent Office on April 15, 2021, the entire contents of which are by reference Incorporated in this application.
本申请涉及医疗器械领域，具体涉及一种脉冲开关信号发生电路与脉冲发生设备。The present application relates to the field of medical devices, in particular to a pulse switch signal generating circuit and a pulse generating device.
背景技术Background technique
在医学领域中，传统的消融方式有射频、微波以及冷冻等消融技术。但传统的消融方式常会对消融区内目标组织以外的其他重要组织造成不可逆的损伤导致并发症。在所述背景技术部分公开的上述信息仅用于加强对本申请的背景的理解，因此它可以包括不构成对本领域普通技术人员已知的现有技术的信息。In the medical field, traditional ablation methods include radiofrequency, microwave, and cryoablation techniques. However, traditional ablation methods often cause irreversible damage to other important tissues other than the target tissue in the ablation area, resulting in complications. The above information disclosed in this Background section is only for enhancement of understanding of the background of the application and therefore it may contain information that does not form the prior art that is already known to a person of ordinary skill in the art.
技术问题technical problem
本申请的一个目的在于提出一种能够产生高压脉冲作用于生物组织的脉冲开关信号发生电路。An object of the present application is to propose a pulse switch signal generating circuit capable of generating high-voltage pulses to act on biological tissues.
技术解决方案technical solutions
为解决上述技术问题，本申请采用如下技术方案：In order to solve the above-mentioned technical problems, the application adopts the following technical solutions:
根据本申请的一个方面，本申请提供一种脉冲开关信号发生电路，包括：According to one aspect of the present application, the present application provides a pulse switch signal generating circuit, comprising:
开关电路，所述开关电路通过通断切换输出脉冲开关信号； a switch circuit, the switch circuit outputs a pulse switch signal by switching on and off;
驱动电路，所述驱动电路具有脉冲信号输入端、电源端以及驱动端；所述驱动端与所述开关电路的受控端连接，以用于控制所述开关电路的通断；a drive circuit, the drive circuit has a pulse signal input end, a power supply end and a drive end; the drive end is connected to the controlled end of the switch circuit for controlling the on-off of the switch circuit;
脉冲控制电路，与所述驱动电路的脉冲信号输入端连接，所述脉冲控制电路用于输出脉冲控制信号；a pulse control circuit, connected to the pulse signal input end of the drive circuit, and the pulse control circuit is used for outputting the pulse control signal;
驱动供电电路，所述驱动供电电路的输出端与所述驱动电路的电源端连接。A drive power supply circuit, the output end of the drive power supply circuit is connected with the power supply end of the drive circuit.
根据本申请一实施例，所述脉冲控制电路包括频率发生器，所述频率发生器根据预置的参数发出至少一路的脉冲控制信号。According to an embodiment of the present application, the pulse control circuit includes a frequency generator, and the frequency generator sends out at least one pulse control signal according to preset parameters.
根据本申请一实施例，所述脉冲控制电路还包括主控制器，所述主控制器与所述频率发生器电连接，以向所述频率发生器发送所述预置的参数，所述预置的参数包括可调整的脉冲频率、脉冲个数和占空比的至少之一。According to an embodiment of the present application, the pulse control circuit further includes a main controller, and the main controller is electrically connected to the frequency generator to send the preset parameters to the frequency generator, and the preset parameters are sent to the frequency generator. The set parameters include at least one of adjustable pulse frequency, pulse number and duty cycle.
根据本申请一实施例，所述主控制器还包括计数电路，所述计数电路与所述频率发生器的输出端电连接，以用于检测所述频率发生器所输出的脉冲的数量。According to an embodiment of the present application, the main controller further includes a counting circuit, and the counting circuit is electrically connected to the output end of the frequency generator for detecting the number of pulses output by the frequency generator.
根据本申请一实施例，所述脉冲开关信号发生电路具有人机交互组件；所述人机交互组件用于接收调节信号，所述调节信号用于对所述脉冲控制信号的脉冲个数、脉冲频率和占空比中的至少之一进行调节。According to an embodiment of the present application, the pulse switch signal generating circuit has a human-computer interaction component; the human-computer interaction component is used to receive an adjustment signal, and the adjustment signal is used to control the number of pulses, the number of pulses of the pulse signal, and the number of pulses. at least one of frequency and duty cycle is adjusted.
根据本申请一实施例，所述脉冲开关信号发生电路还包括光纤通信电路，所述光纤通信电路用于将所述脉冲控制信号以光能的形式发送至所述驱动电路的脉冲信号输入端。According to an embodiment of the present application, the pulse switch signal generating circuit further includes an optical fiber communication circuit, and the optical fiber communication circuit is configured to send the pulse control signal in the form of light energy to the pulse signal input end of the drive circuit.
根据本申请一实施例，所述驱动供电电路包括依次串联的变压装置以及整流电路，所述变压装置的初级侧供交流电源连接，次级侧与所述整流电路连接，所述整流电路的输出端与所述驱动电路的电源端连接。According to an embodiment of the present application, the driving power supply circuit includes a transformer device and a rectifier circuit connected in series in sequence, the primary side of the transformer device is connected to the AC power supply, and the secondary side is connected to the rectifier circuit, and the rectifier circuit The output end is connected to the power end of the drive circuit.
根据本申请一实施例，所述变压装置包括电流互感器，所述电流互感器的初级绕组与所述交流电源连接，所述电流互感器的次级绕组输出交流电压，且与所述整流电路电连接。According to an embodiment of the present application, the transformer device includes a current transformer, the primary winding of the current transformer is connected to the AC power source, the secondary winding of the current transformer outputs an AC voltage, and is connected to the rectifier circuit electrical connection.
根据本申请一实施例，所述驱动供电电路还包括逆变电路，所述逆变电路的输入端供直流电源连接，所述逆变电路的输出端与所述电流互感器的初级绕组连接。According to an embodiment of the present application, the drive power supply circuit further includes an inverter circuit, an input end of the inverter circuit is connected to a DC power supply, and an output end of the inverter circuit is connected to the primary winding of the current transformer.
根据本申请一实施例，所述驱动供电电路还包括电压调整电路，所述电压调整电路与所述整流电路的输出端连接，以将所述整流电路输出的直流电进行直流变换生成第一电压和第二电压；According to an embodiment of the present application, the drive power supply circuit further includes a voltage adjustment circuit, and the voltage adjustment circuit is connected to the output end of the rectifier circuit, so as to convert the DC power output by the rectifier circuit to DC to generate the first voltage and the second voltage;
所述第一电压与所述驱动电路的电源端连接；the first voltage is connected to the power supply terminal of the driving circuit;
所述第二电压通过上拉电阻与所述驱动电路的脉冲信号输入端连接。The second voltage is connected to the pulse signal input end of the driving circuit through a pull-up resistor.
根据本申请一实施例，所述开关电路包括开关管；According to an embodiment of the present application, the switch circuit includes a switch tube;
所述开关电路还包括泄放电路，所述泄放电路连接在所述开关管的受控端与第二端之间；其中，所述开关管的第一端供高压电能输入，所述开关管的第二端供高压电能输出。The switch circuit further includes a discharge circuit, and the discharge circuit is connected between the controlled end and the second end of the switch tube; wherein, the first end of the switch tube is supplied with high-voltage power input, and the switch The second end of the tube is for outputting high-voltage electrical energy.
根据本申请一实施例，所述开关电路还包括分压电路，所述分压电路具有电源输入端，以及分压输出端；According to an embodiment of the present application, the switch circuit further includes a voltage divider circuit, and the voltage divider circuit has a power input end and a voltage divider output end;
所述分压电路的电源输入端供第三电源连接，所述分压输出端与所述开关管的第二端连接，以在所述开关管的受控端上的驱动电压低于第一电压时，使所述开关管的受控端和第二端之间的压差为负电压。The power input end of the voltage divider circuit is connected to a third power source, and the voltage divider output end is connected to the second end of the switch tube, so that the driving voltage on the controlled end of the switch tube is lower than the first voltage, the voltage difference between the controlled end and the second end of the switch tube is a negative voltage.
根据本申请一实施例，所述分压电路包括分压电阻和稳压二极管；According to an embodiment of the present application, the voltage dividing circuit includes a voltage dividing resistor and a Zener diode;
所述稳压二极管的阳极接地；所述分压电阻的第一端为所述电源输入端，所述分压电阻的第二端与所述稳压二极管的阴极连接，以形成所述分压输出端。The anode of the zener diode is grounded; the first end of the voltage divider is the power input end, and the second end of the voltage divider is connected to the cathode of the zener diode to form the voltage divider output.
根据本申请一实施例，所述开关电路包括一个或多个串联或并联连接的开关管；所述驱动电路对应有一个或多个，每一个所述驱动电路对应驱动控制一个或多个所述开关管的通断。According to an embodiment of the present application, the switch circuit includes one or more switch tubes connected in series or in parallel; there are one or more of the drive circuits, and each of the drive circuits correspondingly drives and controls one or more of the drive circuits. On-off of the switch tube.
根据本申请一实施例，所述驱动供电电路有一个或多个，一个所述驱动供电电路对应为一个或多个所述驱动电路提供电源。According to an embodiment of the present application, there are one or more driving power supply circuits, and one driving power supply circuit correspondingly provides power for one or more of the driving circuits.
根据本申请一实施例，所述脉冲控制电路发出一个或多个脉冲控制信号，一个所述脉冲控制信号对应输出到一个或多个所述驱动电路的脉冲信号输入端。According to an embodiment of the present application, the pulse control circuit sends out one or more pulse control signals, and one of the pulse control signals is correspondingly output to one or more pulse signal input terminals of the drive circuit.
根据本申请一实施例，所述电流互感器有1个或多个，在所述电流互感器有多个时，每个所述电流互感器的初级绕组依次串联与所述交流电源连接，每个所述电流互感器的次级绕组分别与所述整流电路连接。According to an embodiment of the present application, there are one or more current transformers, and when there are multiple current transformers, the primary windings of each current transformer are sequentially connected in series with the AC power supply, and each The secondary windings of each of the current transformers are respectively connected to the rectifier circuit.
根据本申请一实施例，所述电流互感器有1个或多个，所述整流电路、所述驱动电路和所述开关电路的数量均与所述电流互感器的数量相等，在所述电流互感器有多个时，每个所述电流互感器的初级绕组依次串联与所述交流电源连接，每个所述电流互感器的次级绕组分别通过一对应的所述整流电路分别为一对应的所述驱动电路供电；According to an embodiment of the present application, there are one or more current transformers, and the numbers of the rectifier circuits, the driving circuits and the switching circuits are all equal to the number of the current transformers. When there are multiple transformers, the primary windings of each of the current transformers are connected in series with the AC power source in sequence, and the secondary windings of each of the current transformers are respectively connected to a corresponding rectifier circuit through a corresponding rectifier circuit. The drive circuit is powered;
1个或多个所述开关电路串联或并联连接，每个所述驱动电路与对应的一所述开关电路连接，以用于控制对应的一所述开关电路的通断。One or more of the switch circuits are connected in series or in parallel, and each of the drive circuits is connected to a corresponding one of the switch circuits for controlling the on-off of the corresponding one of the switch circuits.
根据本申请一实施例，所述脉冲开关信号发生电路还包括传输线，所述传输线串联所述多个电流互感器的初级绕组；所述传输线的电压等级大于或等于20KV。According to an embodiment of the present application, the pulse switch signal generating circuit further includes a transmission line, and the transmission line is connected in series with the primary windings of the multiple current transformers; the voltage level of the transmission line is greater than or equal to 20KV.
本申请还提出一种脉冲发生设备，包括高压电源单元以及所述的脉冲开关信号发生电路；The present application also proposes a pulse generating device, including a high-voltage power supply unit and the pulse switch signal generating circuit;
所述脉冲开关信号发生电路的开关电路、所述高压电源单元与负载形成串联回路，所述开关电路以通过通断切换产生高压脉冲作用在所述负载上。The switch circuit of the pulse switch signal generating circuit, the high-voltage power supply unit and the load form a series loop, and the switch circuit acts on the load by generating high-voltage pulses through on-off switching.
根据本申请一实施例，所述高压电源单元包括高压直流电源以及与所述高压直流电源电连接的储能电容；所述储能电容与所述开关电路、所述负载形成串联回路；According to an embodiment of the present application, the high-voltage power supply unit includes a high-voltage DC power supply and an energy storage capacitor electrically connected to the high-voltage DC power supply; the energy storage capacitor forms a series loop with the switch circuit and the load;
所述储能电容用于存储所述高压直流电源的输出电能，并通过所述开关电路向所述负载提供脉冲电压。The energy storage capacitor is used for storing the output electric energy of the high voltage direct current power supply, and provides a pulse voltage to the load through the switch circuit.
有益效果beneficial effect
本申请方案的脉冲开关信号发生电路包括有开关电路、驱动电路、脉冲控制电路、驱动供电电路。其中，开关电路用于串联于高压电源与生物组织之间，以开关电路在驱动电路的驱动下通过通断切换而在生物组织上产生高压脉冲。其中，驱动供电电路为驱动电路提供电源；脉冲控制电路用于输出脉冲控制信号，以使驱动电路根据该脉冲控制信号输出驱动信号。因此本申请方案能够产生高压脉冲作用于生物组织，在细胞膜上形成不可逆的电穿孔，改变细胞膜通透性，致细胞死亡，能够更精准地对生物组织进行完全的消融；并且通过高压脉冲消融，不会对消融区内的其他重要组织造成不可逆的损伤，从而减少其他传统消融方式所伴有的并发症。因此，本实施例方案所产生的高压脉冲作用在生物组织上时，能够提高消融的有效性。且由于驱动电路的控制信号是来源于脉冲控制电路，驱动电路的供电是来源于驱动供电电路，因此能够有效的避免供电和控制上的相互干扰，提高了驱动电路的工作可靠性。The pulse switch signal generating circuit of the solution of the present application includes a switch circuit, a drive circuit, a pulse control circuit, and a drive power supply circuit. Wherein, the switch circuit is connected in series between the high-voltage power supply and the biological tissue, so that the switch circuit generates high-voltage pulses on the biological tissue through on-off switching under the driving of the driving circuit. The drive power supply circuit provides power for the drive circuit; the pulse control circuit is used for outputting a pulse control signal, so that the drive circuit outputs a drive signal according to the pulse control signal. Therefore, the solution of the present application can generate high-voltage pulses to act on biological tissues, form irreversible electroporation on the cell membrane, change the permeability of the cell membrane, cause cell death, and completely ablate biological tissues more accurately; and through high-voltage pulse ablation, It will not cause irreversible damage to other important tissues in the ablation area, thereby reducing the complications associated with other traditional ablation methods. Therefore, when the high-voltage pulse generated by the solution of this embodiment acts on the biological tissue, the effectiveness of ablation can be improved. And because the control signal of the drive circuit is derived from the pulse control circuit, and the power supply of the drive circuit is derived from the drive power supply circuit, the mutual interference between power supply and control can be effectively avoided, and the operational reliability of the drive circuit can be improved.
应当理解的是，以上的一般描述和后文的细节描述仅是示例性的，并不能限制本申请。It is to be understood that the foregoing general description and the following detailed description are exemplary only and do not limit the application.
附图说明Description of drawings
通过参照附图详细描述其示例实施例，本申请的上述和其它目标、特征及优点将变得更加显而易见。The above and other objects, features and advantages of the present application will become more apparent from the detailed description of example embodiments thereof with reference to the accompanying drawings.
图1是根据一实施例示出的一种脉冲开关信号发生电路、负载、高压电源单元的电路连接框图。FIG. 1 is a circuit connection block diagram of a pulse switch signal generating circuit, a load, and a high-voltage power supply unit according to an embodiment.
图2是根据另一实施例示出的一种脉冲开关信号发生电路、负载、高压电源单元的电路连接框图。Fig. 2 is a circuit connection block diagram of a pulse switch signal generating circuit, a load, and a high-voltage power supply unit according to another embodiment.
图3是根据一实施例示出的一种脉冲发生设备、电网、负载的电路连接框图。Fig. 3 is a circuit connection block diagram of a pulse generating device, a power grid, and a load according to an embodiment.
图4是根据一实施例示出的脉冲开关信号发生电路的驱动电路以及开关电路的电路图。FIG. 4 is a circuit diagram of a drive circuit and a switch circuit of a pulse switch signal generating circuit according to an embodiment.
图5是根据一实施例示出脉冲开关信号发生电路的驱动供电电路的部分电路图。FIG. 5 is a partial circuit diagram illustrating a driving power supply circuit of a pulse switching signal generating circuit according to an embodiment.
图6是根据另一实施例示出的脉冲开关信号发生电路的部分电路结构框图。FIG. 6 is a partial circuit structure block diagram of a pulse switch signal generating circuit according to another embodiment.
本发明的实施方式Embodiments of the present invention
尽管本申请可以容易地表现为不同形式的实施方式，但在附图中示出并且在本说明书中将详细说明的仅仅是其中一些具体实施方式，同时可以理解的是本说明书应视为是本申请原理的示范性说明，而并非旨在将本申请限制到在此所说明的那样。While the present application may readily be embodied in different forms of embodiment, only some of the specific embodiments are shown in the drawings and will be described in detail in this specification, while it is to be understood that this specification is to be regarded as the An exemplary illustration of the principles of the application, and is not intended to limit the application to that described herein.
由此，本说明书中所指出的一个特征将用于说明本申请的一个实施方式的其中一个特征，而不是暗示本申请的每个实施方式必须具有所说明的特征。此外，应当注意的是本说明书描述了许多特征。尽管某些特征可以组合在一起以示出可能的***设计，但是这些特征也可用于其他的未明确说明的组合。由此，除非另有说明，所说明的组合并非旨在限制。Thus, a feature indicated in this specification will be used to describe one of the features of an embodiment of the application without implying that every embodiment of the application must have the stated feature. Furthermore, it should be noted that this specification describes a number of features. Although certain features may be combined together to illustrate possible system designs, these features may also be used in other combinations not explicitly stated. Thus, unless otherwise stated, the combinations described are not intended to be limiting.
在附图所示的实施方式中，方向的指示（诸如上、下、左、右、前和后）用于解释本申请的各种元件的结构和运动不是绝对的而是相对的。当这些元件处于附图所示的位置时，这些说明是合适的。如果这些元件的位置的说明发生改变时，则这些方向的指示也相应地改变。In the embodiments shown in the drawings, directional indications (such as up, down, left, right, front and rear) are used to explain the structure and movement of various elements of the present application not absolute but relative. These descriptions are appropriate when the elements are in the positions shown in the drawings. If the description of the positions of these elements changes, the indications of these directions change accordingly.
现在将参考附图更全面地描述示例实施方式。然而，示例实施方式能够以多种形式实施，且不应被理解为限于在此阐述的范例；相反，提供这些示例实施方式使得本申请的描述将更加全面和完整，并将示例实施方式的构思全面地传达给本领域的技术人员。附图仅为本申请的示意性图解，并非一定是按比例绘制。图中相同的附图标记表示相同或类似的部分，因而将省略对它们的重复描述。Example embodiments will now be described more fully with reference to the accompanying drawings. Example embodiments, however, can be embodied in various forms and should not be construed as limited to the examples set forth herein; rather, these example embodiments are provided so that the description of this application will be thorough and complete, and will convey the concepts of the example embodiments It will be fully conveyed to those skilled in the art. The drawings are merely schematic illustrations of the present application and are not necessarily drawn to scale. The same reference numerals in the drawings denote the same or similar parts, and thus their repeated descriptions will be omitted.
以下结合本说明书的附图，对本申请的较佳实施方式予以进一步地详尽阐述。The preferred embodiments of the present application will be further elaborated below with reference to the accompanying drawings of the present specification.
请参阅图1，图1是根据一实施例示出的一种脉冲开关信号发生电路1、负载3、高压电源单元2的电路连接框图。本申请首先提出一种脉冲开关信号发生电路1用于脉冲发生设备。脉冲开关信号发生电路1包括开关电路11、驱动电路12、脉冲控制电路13和驱动供电电路14。开关电路11串联于高压电源单元2与负载3之间，以通过通断切换输出脉冲开关信号，从而在负载3上产生高压脉冲。在此负载3可以是待消融的生物组织。驱动电路12具有脉冲信号输入端、电源端以及驱动端；驱动端与开关电路11的受控端连接，以用于控制开关电路11的通断；脉冲控制电路13与驱动电路12的脉冲信号输入端连接，脉冲控制电路13用于输出脉冲控制信号；驱动供电电路14的输出端与驱动电路12的电源端连接。Please refer to FIG. 1 , which is a circuit connection block diagram of a pulse switch signal generating circuit 1 , a load 3 , and a high-voltage power supply unit 2 according to an embodiment. The present application first proposes a pulse switch signal generating circuit 1 for a pulse generating device. The pulse switch signal generating circuit 1 includes a switch circuit 11 , a drive circuit 12 , a pulse control circuit 13 and a drive power supply circuit 14 . The switch circuit 11 is connected in series between the high-voltage power supply unit 2 and the load 3 to output a pulse switch signal by switching on and off, thereby generating a high-voltage pulse on the load 3 . The load 3 here can be biological tissue to be ablated. The driving circuit 12 has a pulse signal input terminal, a power supply terminal and a driving terminal; the driving terminal is connected to the controlled terminal of the switching circuit 11 for controlling the on-off of the switching circuit 11; the pulse signal input of the pulse control circuit 13 and the driving circuit 12 The pulse control circuit 13 is used for outputting the pulse control signal; the output terminal of the driving power supply circuit 14 is connected to the power supply terminal of the driving circuit 12 .
在本申请中，通过脉冲控制电路13为驱动电路12提供脉冲控制信号，通过驱动供电电路14为驱动电路12提供电源，从而使驱动电路12能够输出驱动信号，用于控制开关电路11的通断，高压电源单元2的输出通过开关电路11的通断控制，而在负载3上产生高压脉冲。通过脉冲控制电路13的控制，能够产生高压脉冲，在细胞膜上形成不可逆的电穿孔，改变细胞膜通透性，致细胞死亡，能够更精准地对生物组织进行完全的消融；并且通过高压脉冲消融，不会对消融区内目标组织以外的其他重要组织造成不可逆的损伤，从而减少其他传统消融方式所伴有的并发症。因此，本实施例方案所产生的高压脉冲作用在生物组织上时，能够提高消融的有效性。且由于驱动电路12的控制信号是来源于脉冲控制电路13，驱动电路12的供电是来源于驱动供电电路14，因此能够有效的避免供电和控制上的相互干扰，提高了驱动电路12的工作可靠性。In this application, the pulse control circuit 13 provides the driving circuit 12 with a pulse control signal, and the driving power supply circuit 14 provides power for the driving circuit 12, so that the driving circuit 12 can output the driving signal for controlling the on-off of the switch circuit 11. , the output of the high-voltage power supply unit 2 is controlled by the on-off of the switch circuit 11 , and a high-voltage pulse is generated on the load 3 . Through the control of the pulse control circuit 13, a high-voltage pulse can be generated to form irreversible electroporation on the cell membrane, change the permeability of the cell membrane, cause cell death, and completely ablate biological tissue more accurately; and through high-voltage pulse ablation, It will not cause irreversible damage to other important tissues other than the target tissue in the ablation area, thereby reducing the complications associated with other traditional ablation methods. Therefore, when the high-voltage pulse generated by the solution of this embodiment acts on the biological tissue, the effectiveness of ablation can be improved. And because the control signal of the drive circuit 12 is derived from the pulse control circuit 13, and the power supply of the drive circuit 12 is derived from the drive power supply circuit 14, the mutual interference between power supply and control can be effectively avoided, and the operation reliability of the drive circuit 12 is improved. sex.
请参阅图2，图2是根据另一实施例示出的一种脉冲开关信号发生电路1、负载3、高压电源单元2的电路连接框图。在一实施例中，脉冲控制电路13包括频率发生器131，频率发生器131根据预置的参数发出至少一路的脉冲控制信号；在频率发生器131根据预置的参数发出两路脉冲控制信号时：驱动电路12可以有一个或两个，分别在两路脉冲控制信号的控制下生成两路驱动信号；开关电路11有两个，两路驱动信号对应驱动两个开关电路11工作。Please refer to FIG. 2 , which is a circuit connection block diagram of a pulse switch signal generating circuit 1 , a load 3 , and a high-voltage power supply unit 2 according to another embodiment. In one embodiment, the pulse control circuit 13 includes a frequency generator 131, and the frequency generator 131 sends out at least one pulse control signal according to preset parameters; when the frequency generator 131 sends out two pulse control signals according to the preset parameters : There may be one or two driving circuits 12 , which respectively generate two driving signals under the control of two pulse control signals; there are two switching circuits 11 , and the two driving signals correspondingly drive two switching circuits 11 to work.
当驱动电路12有两个时，还可以对应设置两个高压电源单元2，两个高压电源单元2分别为正高压电源以及负高压电源。因此通过控制两个开关电路11交替开通，从而能够在负载3上产生正负交替的双极性高压脉冲，双极性高压脉冲电场分布更均匀，可减少肌肉收缩，提高消融效果，并且降低了对开关电路11切换频率的要求。When there are two driving circuits 12 , two high-voltage power supply units 2 may be correspondingly provided, and the two high-voltage power supply units 2 are respectively a positive high-voltage power supply and a negative high-voltage power supply. Therefore, by controlling the two switch circuits 11 to be turned on alternately, bipolar high-voltage pulses with alternating positive and negative can be generated on the load 3, and the electric field distribution of the bipolar high-voltage pulses is more uniform, which can reduce muscle contraction, improve the ablation effect, and reduce the Requirements for the switching frequency of the switching circuit 11 .
在此频率发生器131可以独立工作，通过存储在内部存储器内的参数控制发出脉冲控制信号。如图3所示，在另一实施例中，脉冲控制电路13还包括主控制器132，主控制器132与频率发生器131电连接，以向频率发生器131发送预置的参数，预置的参数包括可调整的脉冲频率、脉冲个数和占空比的至少之一。主控制器132具体可以是ARM处理器，当然也可以是MCU或CPU。Here, the frequency generator 131 can work independently, and send out the pulse control signal through the parameter control stored in the internal memory. As shown in FIG. 3 , in another embodiment, the pulse control circuit 13 further includes a main controller 132 , and the main controller 132 is electrically connected to the frequency generator 131 to send preset parameters to the frequency generator 131 . The parameters include at least one of adjustable pulse frequency, pulse number and duty cycle. The main controller 132 may specifically be an ARM processor, and certainly may be an MCU or a CPU.
具体的，在脉冲开关信号发生电路1工作时，主控制器132将预置参数发送至频率发生器131，频率发生器131根据该预置参数生成脉冲控制信号发送至驱动电路12。Specifically, when the pulse switch signal generating circuit 1 is working, the main controller 132 sends preset parameters to the frequency generator 131 , and the frequency generator 131 generates pulse control signals according to the preset parameters and sends them to the driving circuit 12 .
在一实施例中，主控制器132根据当前脉冲发生设备的工作模式，自动生成预置参数发送至频率发生器131。在另一示例中，主控制器132根据用户的对特定参数的调节而生成预置参数。示意性的，在脉冲开关信号发生电路上具有人机交互组件。人机交互组件用于接收调节信号，调节信号用于对脉冲控制信号的脉冲个数、脉冲频率和占空比中的至少之一进行调节。In one embodiment, the main controller 132 automatically generates preset parameters and sends them to the frequency generator 131 according to the current working mode of the pulse generating device. In another example, the main controller 132 generates preset parameters according to a user's adjustment of a specific parameter. Illustratively, there are human-computer interaction components on the pulse switch signal generating circuit. The human-computer interaction component is used to receive the adjustment signal, and the adjustment signal is used to adjust at least one of the pulse number, the pulse frequency and the duty cycle of the pulse control signal.
人机交互组件可以是按键组件、触控屏组件、上位机或者语音输入组件等。通过人机交互组件，用户可以对脉冲频率、脉冲个数和占空比的至少之一进行调节，主控制器132根据所接收到的调节信号生成预置参数发送至频率发生器131，使频率发生器131所发出的脉冲控制信号相应改变。The human-computer interaction component can be a key component, a touch screen component, a host computer, or a voice input component. Through the human-computer interaction component, the user can adjust at least one of the pulse frequency, the number of pulses and the duty cycle. The main controller 132 generates preset parameters according to the received adjustment signal and sends them to the frequency generator 131 to make the frequency The pulse control signal issued by the generator 131 changes accordingly.
在一实施例中，主控制器132还包括计数电路，计数电路与频率发生器131的输出端电连接，以用于检测频率发生器131所输出的脉冲的数量。在此，主控制器132可以是主控芯片，主控芯片内集成有计数电路。计数电路根据频率发生器131输出的脉冲控制信号的电平翻转次数进行计数。In one embodiment, the main controller 132 further includes a counting circuit, which is electrically connected to the output terminal of the frequency generator 131 for detecting the number of pulses output by the frequency generator 131 . Here, the main controller 132 may be a main control chip, and a counting circuit is integrated in the main control chip. The counting circuit counts the number of inversions of the level of the pulse control signal output by the frequency generator 131 .
请参阅图3，图3是根据一实施例示出的一种脉冲发生设备、电网、负载的电路连接框图。为了能够向用户显示当前脉冲控制信号的数量，还可以设置显示装置5，显示装置5与主控制器132之间、主控制器132与频率发生器131之间均采用光纤通信，以实现电气隔离，提高脉冲发生设备的绝缘等级，减小了病人和操作者受高压电击的危害。在此，可以设置第一辅助电源电路6，电网4电压输入到第一辅助电源电路6中，经过第一辅助电源电路6处理后输出直流电压，该直流电压用于为显示装置5供电。Please refer to FIG. 3 . FIG. 3 is a circuit connection block diagram of a pulse generating device, a power grid, and a load according to an embodiment. In order to be able to display the current number of pulse control signals to the user, a display device 5 can also be provided, and optical fiber communication is used between the display device 5 and the main controller 132 and between the main controller 132 and the frequency generator 131 to achieve electrical isolation. , to improve the insulation level of the pulse generating equipment, and reduce the danger of high-voltage electric shock for patients and operators. Here, a first auxiliary power supply circuit 6 may be provided, and the voltage of the grid 4 is input into the first auxiliary power supply circuit 6, and after being processed by the first auxiliary power supply circuit 6, a DC voltage is output, and the DC voltage is used to supply power to the display device 5.
请参阅图3和图4，其中，图4是根据一实施例示出的脉冲开关信号发生电路的驱动电路以及开关电路的电路图。在一实施例中，脉冲开关信号发生电路1还包括光纤通信电路15，光纤通信电路15用于将脉冲控制信号以光能的形式发送至驱动电路12的脉冲信号输入端；光纤通信电路15包括依次连接的电光转换电路、传输电路和光电转换电路153，其中：电光转换电路与脉冲控制电路13连接，用于将脉冲控制信号的电信号转换为光信号；传输电路用于将光信号传输到光电转换电路153；光电转换电路153用于将光信号转换为电信号，并输出到驱动电路12的脉冲信号输入端。Please refer to FIG. 3 and FIG. 4 , wherein FIG. 4 is a circuit diagram of a drive circuit and a switch circuit of a pulse switch signal generating circuit according to an embodiment. In one embodiment, the pulse switch signal generating circuit 1 further includes an optical fiber communication circuit 15, and the optical fiber communication circuit 15 is used for sending the pulse control signal in the form of light energy to the pulse signal input end of the driving circuit 12; the optical fiber communication circuit 15 includes: The electro-optical conversion circuit, the transmission circuit and the photoelectric conversion circuit 153 are connected in sequence, wherein: the electro-optical conversion circuit is connected to the pulse control circuit 13 for converting the electrical signal of the pulse control signal into an optical signal; the transmission circuit is used for transmitting the optical signal to the pulse control circuit 13. Photoelectric conversion circuit 153 ; the photoelectric conversion circuit 153 is used to convert the optical signal into an electrical signal and output it to the pulse signal input end of the driving circuit 12 .
在此，电光转换电路具体可以为发光二极管、红外LED或者激光二极管等。传输电路可以为光纤，光电转换电路可以是光耦。Here, the electro-optical conversion circuit may specifically be a light emitting diode, an infrared LED, a laser diode, or the like. The transmission circuit can be an optical fiber, and the photoelectric conversion circuit can be an optocoupler.
图4中，驱动电路12为驱动芯片U2，该驱动芯片U2具有脉冲信号输入端IN，脉冲信号输入端IN通过第一电阻R1与光电转换电路153电连接，以接收经过光电转换电路153转换后的电信号；脉冲信号输入端IN通过第二电阻R2接地，接地端为VCC_0。In FIG. 4 , the driving circuit 12 is a driving chip U2, which has a pulse signal input terminal IN, and the pulse signal input terminal IN is electrically connected to the photoelectric conversion circuit 153 through the first resistor R1, so as to receive the signal converted by the photoelectric conversion circuit 153. The electrical signal of the pulse signal; the pulse signal input terminal IN is grounded through the second resistor R2, and the ground terminal is VCC_0.
相关技术中，开关电路11在工作过程中，常出现工作不稳定的情况，从而造成所输出的高压脉冲不稳定的问题。In the related art, during the operation of the switch circuit 11, unstable operation often occurs, thereby causing the problem that the output high-voltage pulse is unstable.
为应对这一问题，请参阅3和图5，其中图5是根据一实施例示出脉冲开关信号发生电路的驱动供电电路14的部分电路图。在一实施例中，驱动供电电路14包括依次串联的变压装置142以及整流电路143，变压装置142的初级侧供交流电源连接，次级侧与整流电路143连接，整流电路143的输出端与驱动电路12的电源端连接。To address this problem, please refer to FIG. 3 and FIG. 5 , wherein FIG. 5 is a partial circuit diagram illustrating the driving power supply circuit 14 of the pulse switch signal generating circuit according to an embodiment. In one embodiment, the drive power supply circuit 14 includes a transformer device 142 and a rectifier circuit 143 that are connected in series. The primary side of the transformer device 142 is connected to the AC power supply, and the secondary side is connected to the rectifier circuit 143. The output end of the rectifier circuit 143 It is connected to the power supply terminal of the driving circuit 12 .
其中变压装置142具有隔离变压作用，具体可以是电流互感器L或者变压器。在一具体的示例中，变压装置142包括电流互感器L，电流互感器L的初级绕组与交流电源连接，电流互感器L的次级绕组输出交流电压，且与整流电路143电连接。整流电路143可以包括但不限于是全桥整流电路。在此电流互感器L的电压初级绕组和次级绕组的匝数比在1：10~1:20之间，具体可以是1:14。The transformer device 142 has the function of isolating and transforming, and may specifically be a current transformer L or a transformer. In a specific example, the transformer device 142 includes a current transformer L, the primary winding of the current transformer L is connected to an AC power source, and the secondary winding of the current transformer L outputs an AC voltage and is electrically connected to the rectifier circuit 143 . The rectifier circuit 143 may include, but is not limited to, a full-bridge rectifier circuit. Here, the turns ratio of the voltage primary winding and the secondary winding of the current transformer L is between 1:10 and 1:20, specifically 1:14.
具体的，整流电路143可以采用二极管整流电路，在图5中，D1、D2、D3、D4组成二极管整流电路143，稳压二极管D5用于稳定二极管整流电路的输出。电容C1用于滤除杂波。Specifically, the rectifier circuit 143 may adopt a diode rectifier circuit. In FIG. 5 , D1, D2, D3, and D4 form the diode rectifier circuit 143, and the zener diode D5 is used to stabilize the output of the diode rectifier circuit. Capacitor C1 is used to filter out clutter.
请参阅4和图5。在一实施例中，驱动供电电路14还包括电压调整电路144，电压调整电路144与整流电路143的输出端连接，以将整流电路143输出的直流电进行直流变换生成第一电压VCC1和第二电压VCC2；第一电压VCC1通过上拉电阻R3与驱动电路12的脉冲信号输入端IN连接；第二电压VCC2与驱动电路12的电源端VDD连接。See 4 and Figure 5. In one embodiment, the drive power supply circuit 14 further includes a voltage adjustment circuit 144, and the voltage adjustment circuit 144 is connected to the output end of the rectification circuit 143, so as to convert the DC power output by the rectification circuit 143 to DC to generate the first voltage VCC1 and the second voltage. VCC2; the first voltage VCC1 is connected to the pulse signal input terminal IN of the driving circuit 12 through the pull-up resistor R3; the second voltage VCC2 is connected to the power supply terminal VDD of the driving circuit 12.
电压调整电路144具体可以是电压变换芯片。根据驱动芯片脉冲输入端引脚所需要的上拉电压设定第一电压VCC1。根据驱动电路12所需要的供电电压设定第二电压VCC2。Specifically, the voltage adjustment circuit 144 may be a voltage conversion chip. The first voltage VCC1 is set according to the pull-up voltage required by the pulse input pin of the driving chip. The second voltage VCC2 is set according to the power supply voltage required by the driving circuit 12 .
在一具体的示例中，第一电压设定为2~8V。具体可以是5V。第二电压设定为20V~30V，具体可以为25V。该第一电压VCC1的设定值不仅能够满足正常驱动开关电路11的要求，还能够在为开关电路11设置了反向关断电压的前提下，仍然能够满足对开关电路11的正常驱动，具体将在下述实施例中阐述。In a specific example, the first voltage is set to 2~8V. Specifically, it can be 5V. The second voltage is set to be 20V-30V, specifically 25V. The set value of the first voltage VCC1 can not only meet the requirements of driving the switch circuit 11 normally, but also can still meet the normal driving of the switch circuit 11 under the premise of setting a reverse turn-off voltage for the switch circuit 11 . It will be illustrated in the following examples.
由于脉冲控制信号的工作频率高，脉冲波形前后沿陡峭、谐波丰富。在该实施例中，通过设置为驱动电路12供电的电源经过电流互感器L，而脉冲控制信号未经过该电流互感器L，以将电源与脉冲该控制信号进行隔离，为驱动电路12供电的电源因此不会受到脉冲控制信号的谐波干扰，从而能够提高对驱动电路12的供电稳定性，由此提高了驱动电路12的工作稳定性，减少了因驱动电路的供电电源不稳定而造成的输出高压脉冲不稳定的情况。Due to the high operating frequency of the pulse control signal, the front and rear edges of the pulse waveform are steep and the harmonics are rich. In this embodiment, the power supply for the driving circuit 12 is set to pass through the current transformer L, while the pulse control signal does not pass through the current transformer L, so as to isolate the power supply from the pulsed control signal, and provide power for the driving circuit 12. Therefore, the power supply will not be interfered by the harmonics of the pulse control signal, so that the stability of the power supply to the driving circuit 12 can be improved, thereby improving the working stability of the driving circuit 12 and reducing the instability of the power supply of the driving circuit. The output high voltage pulse is unstable.
请参阅图3和图5，在一实施例中，驱动供电电路14还包括逆变电路141，逆变电路141的输入端供直流电源连接，逆变电路141的输出端与电流互感器L的初级绕组连接。逆变电路141在此可以通过搭建逆变桥电路或者采用逆变芯片。3 and FIG. 5, in one embodiment, the driving power supply circuit 14 further includes an inverter circuit 141, the input end of the inverter circuit 141 is connected to the DC power supply, and the output end of the inverter circuit 141 is connected to the current transformer L Primary winding connection. The inverter circuit 141 can be constructed by constructing an inverter bridge circuit or using an inverter chip.
请参阅图3，其中，可以通过电网4电压接入隔离变压器21初级侧，在隔离变压器21次级侧连接至第二辅助电源电路145，隔离变压器21的原边绕组和副边绕组的匝比可以是1:1，这样既起到隔离的作用，也能满足内部电路对电压的需求。在其他实施例中，隔离变压器21的原边绕组和副边绕组的匝比也可以根据实际需求做调整。第二辅助电源电路145有两路电压输出，第一路电压输出大约为24V，第二路电压输出大约为15V。第一路电压输出用于为主控制器132供电。第二路电压输出为上述直流电源，用于输入至逆变电路141。逆变电路141内包括有升压变压器，以对15V电压进行升压，升压且逆变后输出交流电压。在此，通过逆变电路141的升压处理，能够提高对驱动供电电路14输出的电压值，较高的驱动供电电压能够提高开关电路11中开关管Q1的开断速度，提高响应速度，从而能够提高脉冲发生设备所输出的高压脉冲的频率。Please refer to FIG. 3, wherein the primary side of the isolation transformer 21 can be connected to the voltage of the grid 4, and the secondary side of the isolation transformer 21 is connected to the second auxiliary power circuit 145. The turns ratio of the primary winding and the secondary winding of the isolation transformer 21 It can be 1:1, which not only plays the role of isolation, but also meets the voltage requirements of the internal circuit. In other embodiments, the turns ratio of the primary winding and the secondary winding of the isolation transformer 21 can also be adjusted according to actual requirements. The second auxiliary power circuit 145 has two voltage outputs, the first voltage output is about 24V, and the second voltage output is about 15V. The first voltage output is used to power the main controller 132 . The second voltage output is the above-mentioned DC power source, and is used for input to the inverter circuit 141 . The inverter circuit 141 includes a step-up transformer to boost the 15V voltage, and output the AC voltage after boosting and inverting. Here, the voltage value output to the drive power supply circuit 14 can be increased through the boosting process of the inverter circuit 141, and a higher drive power supply voltage can improve the switching speed of the switch tube Q1 in the switch circuit 11 and improve the response speed, thereby The frequency of the high-voltage pulse output by the pulse generating device can be increased.
本实施例利用直流电源进行逆变后生成交流电源，从而能够提高该交流电源的稳定性。该交流电源进一步经过电流互感器L和整流电路143为驱动电路12供电，因此提高了驱动电路12的供电稳定性。In this embodiment, the AC power is generated after the DC power is inverted, so that the stability of the AC power can be improved. The AC power supply further supplies power to the drive circuit 12 through the current transformer L and the rectifier circuit 143 , thus improving the power supply stability of the drive circuit 12 .
请参阅图4，在一实施例中，开关电路11包括开关管Q1；开关电路11还包括泄放电路16，泄放电路16连接在开关管Q1的受控端与第二端之间；其中，开关管Q1的第一端供高压电源的正极输入，开关管Q1的第二端与高压电源的负极连接，以供高压电能输出。开关管Q1的受控端通过一第四电阻R4与驱动电路12输出端OUT连接。在此，开关管Q1的第二端可以通过电容C3接地，可以为驱动开关管Q1的脉冲信号提供一个低阻抗的交流通路。在此开关管Q1可以包括但不限于是MOS管、三极管或IGBT。以NMOS管为例说明。受控端对应为MOS管的栅极，第一端为漏极，第二端为源极。Referring to FIG. 4, in one embodiment, the switch circuit 11 includes a switch tube Q1; the switch circuit 11 further includes a discharge circuit 16, and the discharge circuit 16 is connected between the controlled end and the second end of the switch tube Q1; wherein , the first end of the switch tube Q1 is input to the positive pole of the high voltage power supply, and the second end of the switch tube Q1 is connected to the negative pole of the high voltage power supply for high voltage power output. The controlled end of the switch tube Q1 is connected to the output end OUT of the driving circuit 12 through a fourth resistor R4. Here, the second end of the switch tube Q1 can be grounded through the capacitor C3, which can provide a low-impedance AC path for the pulse signal driving the switch tube Q1. Here, the switch transistor Q1 may include, but is not limited to, a MOS transistor, a triode or an IGBT. Take NMOS tube as an example. The controlled end corresponds to the gate of the MOS transistor, the first end is the drain, and the second end is the source.
泄放电路16可以包括一个或多个电阻，一个或多个电阻可以以串联或并联的方式进行连接。在一具体的实施例中，泄放电路16包括第五电阻R5，第五电阻R5连接在开关管Q1的受控端与第二端之间。当开关管Q1关断后，第五电阻R5能够与开关管内的二极管形成放电回路，以对开关管Q1内的电能进行泄放，以减少开关管Q1管的关断损耗和损坏概率，提高高压脉冲发生电路的工作可靠性。The bleeder circuit 16 may include one or more resistors, which may be connected in series or parallel. In a specific embodiment, the discharge circuit 16 includes a fifth resistor R5, and the fifth resistor R5 is connected between the controlled end and the second end of the switching transistor Q1. When the switch tube Q1 is turned off, the fifth resistor R5 can form a discharge loop with the diode in the switch tube to discharge the electric energy in the switch tube Q1, so as to reduce the turn-off loss and damage probability of the switch tube Q1 tube, and improve the high voltage The working reliability of the pulse generating circuit.
进一步的，开关电路11还包括分压电路17，分压电路17具有电源输入端，以及分压输出端；分压电路17的电源输入端供第三电源连接，分压输出端与开关管Q1的第二端连接，以在开关管Q1的受控端上的驱动电压低于第一电压时，使开关管Q1的受控端和第二端之间的压差为负电压。Further, the switch circuit 11 further includes a voltage divider circuit 17, and the voltage divider circuit 17 has a power input terminal and a voltage divider output terminal; the power source input terminal of the voltage divider circuit 17 is connected to a third power source, and the voltage divider output terminal is connected to the switch tube Q1. The second end of the switch tube Q1 is connected to make the voltage difference between the controlled end and the second end of the switch tube Q1 a negative voltage when the driving voltage on the controlled end of the switch tube Q1 is lower than the first voltage.
分压电路17可以采用多个电阻通过串联组成，也可以采用电阻与稳压二极管组成。在一具体的实施例中，分压电路17包括分压电阻R6和稳压二极管D6；稳压二极管D6的阳极接地；分压电阻R6的第一端为电源输入端，分压电阻R6的第二端与稳压二极管D6的阴极连接，以形成分压输出端。电源输入端与第三电源连接，在此可以设置第三电源为上述第二电压VCC2。分压电阻R6的两端可以并联有第二电容C2，第二电容C2可以滤除第二电压VCC2中的尖峰电压，防止第二电压VCC2的电压突变造成分压输出端电压不稳定的情况，可以改善分压电路17的频率响应特性。The voltage divider circuit 17 can be composed of a plurality of resistors in series, or can be composed of a resistor and a zener diode. In a specific embodiment, the voltage dividing circuit 17 includes a voltage dividing resistor R6 and a Zener diode D6; the anode of the Zener diode D6 is grounded; the first end of the voltage dividing resistor R6 is the power input terminal, and the third The two terminals are connected to the cathode of the Zener diode D6 to form a voltage divider output terminal. The power input terminal is connected to the third power source, and the third power source can be set to the above-mentioned second voltage VCC2. Both ends of the voltage dividing resistor R6 can be connected with a second capacitor C2 in parallel, and the second capacitor C2 can filter the peak voltage in the second voltage VCC2 to prevent the voltage of the second voltage VCC2 from causing the voltage of the voltage divider output terminal to become unstable. The frequency response characteristic of the voltage dividing circuit 17 can be improved.
在该实施例中，分压电阻R6与稳压二极管D6形成分压电路17，通过设置分压电阻R6的值，能够在稳压二极管D6上产生大约5V的电压。稳压二极管D6阴极与开关管Q1的第二端连接，因此开关管Q1的第二端上的电压大约为5V，因此当驱动电路12输出的驱动电压低于第一电压（如5V）时，开关管Q1会因第二端与受控端之间的压差为负压而加速关断。因此本实施例能够提高开关管Q1的关闭速度，减少开关管Q1管的关断损耗和损坏概率，提高高压脉冲发生电路的工作可靠性。In this embodiment, the voltage dividing resistor R6 and the zener diode D6 form a voltage dividing circuit 17. By setting the value of the voltage dividing resistor R6, a voltage of about 5V can be generated on the zener diode D6. The cathode of the Zener diode D6 is connected to the second terminal of the switch tube Q1, so the voltage on the second terminal of the switch tube Q1 is about 5V, so when the driving voltage output by the driving circuit 12 is lower than the first voltage (eg 5V), The switch tube Q1 will be turned off quickly because the pressure difference between the second end and the controlled end is negative pressure. Therefore, this embodiment can improve the turn-off speed of the switch tube Q1, reduce the turn-off loss and damage probability of the switch tube Q1, and improve the working reliability of the high-voltage pulse generating circuit.
为了进一步提高脉冲开关信号发生电路1的工作可靠性，请参阅图4，在一实施例中，设置在开关管Q1的第一端和第二端之间并联至少一个续流二极管。续流二极管的阴极与高压电源正极连接，阳极与高压电源负极连接。为负载中产生的感性负荷提供返回路径，提高高压脉冲发生电路的工作可靠性。图4中续流二极管有三个，分别为D7、D8、D9。In order to further improve the operational reliability of the pulse switch signal generating circuit 1 , please refer to FIG. 4 , in one embodiment, at least one freewheeling diode is connected in parallel between the first end and the second end of the switch Q1 . The cathode of the freewheeling diode is connected with the positive pole of the high-voltage power supply, and the anode is connected with the negative pole of the high-voltage power supply. Provide a return path for the inductive load generated in the load, and improve the working reliability of the high-voltage pulse generating circuit. In Figure 4, there are three freewheeling diodes, namely D7, D8, and D9.
请参阅图6，图6是根据另一实施例示出的脉冲开关信号发生电路1的部分电路结构框图。进一步的，还可以设置开关电路11包括一个或多个串联或并联连接的开关管Q1；驱动电路12对应有一个或多个，每一个驱动电路12对应驱动控制一个或多个开关管Q1的通断。Please refer to FIG. 6 . FIG. 6 is a partial circuit structure block diagram of a pulse switch signal generating circuit 1 according to another embodiment. Further, the switch circuit 11 can also be set to include one or more switch tubes Q1 connected in series or in parallel; the drive circuit 12 corresponds to one or more, and each drive circuit 12 correspondingly drives and controls the on-off of one or more switch tubes Q1. break.
在该实施例中，开关管Q1可以采用碳化硅MOS管。多个碳化硅MOS管采用并联或串联的方式级联，利用多个小电流低电压MOS管实现大电流高电压的开关电路11，有效的提高输出脉冲发生设备所输出的高压脉冲的电压和电流等级；并且由于采用了小电流低电压的MOS管，因此能够降低制造成本。In this embodiment, the switch transistor Q1 can be a silicon carbide MOS transistor. A plurality of silicon carbide MOS tubes are cascaded in parallel or in series, and a large current and high voltage switching circuit 11 is realized by using a plurality of small current and low voltage MOS tubes, which effectively improves the voltage and current of the high voltage pulse output by the output pulse generator. level; and because of the use of a low-current and low-voltage MOS tube, the manufacturing cost can be reduced.
当仅有一个开关电路11时，可以配置一个驱动供电电路14、一个脉冲控制信号。当有多个开关电路11时，对应于驱动供电电路14的配置可以有多种实施例。When there is only one switch circuit 11, one drive power supply circuit 14 and one pulse control signal can be configured. When there are a plurality of switch circuits 11 , there may be various embodiments corresponding to the configuration of the drive power supply circuit 14 .
在一实施例中，驱动供电电路14有一个或多个，一个驱动供电电路14对应为一个或多个驱动电路12提供电源。在一示例中，多个驱动供电电路14一一对应的为多个驱动电路12供电。该示例能够提高每个开关电路11供电的独立性，减少每个开关电路11所受到的供电干扰，从而保证脉冲发生设备的工作可靠性。在另一示例中，也可以是一个驱动供电电路14同时为两个及两个以上的驱动电路12供电，该实施例能够减少驱动供电电路14的数量，有利于减小脉冲发生设备的体积且降低生产成本。In one embodiment, there are one or more driving power supply circuits 14 , and one driving power supply circuit 14 correspondingly provides power for one or more driving circuits 12 . In an example, the plurality of driving power supply circuits 14 are in a one-to-one correspondence to supply power to the plurality of driving circuits 12 . This example can improve the independence of the power supply of each switch circuit 11 , and reduce the power supply interference received by each switch circuit 11 , thereby ensuring the working reliability of the pulse generating device. In another example, one drive power supply circuit 14 can also supply power to two or more drive circuits 12 at the same time. This embodiment can reduce the number of drive power supply circuits 14 , which is beneficial to reduce the volume of the pulse generating device. reduce manufacturing cost.
进一步的，在一实施例中，脉冲控制电路13发出一个或多个脉冲控制信号，一个脉冲控制信号对应输出到一个或多个驱动电路12的脉冲信号输入端。在一示例中，多个脉冲控制电路13一一对应的为多个驱动电路12提供脉冲控制信号。该示例能够提高每个开关电路11受控的独立性，减少每个开关电路11在接收脉冲控制信号的过程中所受到的干扰，从而保证脉冲发生设备的工作可靠性。在另一示例中，也可以是一个脉冲控制电路13同时为两个及两个以上的驱动电路12提供脉冲控制信号。该实施例能够提高开关电路11的工作同步性，有利于减小脉冲发生设备的体积且降低生产成本。Further, in one embodiment, the pulse control circuit 13 sends out one or more pulse control signals, and one pulse control signal is outputted to one or more pulse signal input terminals of the driving circuit 12 correspondingly. In an example, the plurality of pulse control circuits 13 provide pulse control signals to the plurality of driving circuits 12 in a one-to-one correspondence. This example can improve the controllability of each switch circuit 11 and reduce the interference received by each switch circuit 11 in the process of receiving the pulse control signal, thereby ensuring the working reliability of the pulse generating device. In another example, one pulse control circuit 13 may simultaneously provide pulse control signals for two or more driving circuits 12 . This embodiment can improve the working synchronization of the switching circuit 11 , which is beneficial to reduce the volume of the pulse generating device and reduce the production cost.
在一实施例中，当电源电路有一个或多个时，电流互感器L也对应有1个或多个，在此设置整流电路143、驱动电路12和开关电路11的数量均与电流互感器L的数量相等，在电流互感器L有多个时，每个电流互感器L的初级绕组依次串联与交流电源（逆变电路141的输出端）连接，每个电流互感器L的次级绕组分别通过一对应的整流电路143分别为一对应的驱动电路12供电；1个或多个开关电路11串联或并联连接，每个驱动电路12与对应的一开关电路11连接，以用于控制对应的一开关电路11的通断。In one embodiment, when there are one or more power supply circuits, there are also one or more current transformers L. Here, the number of rectifier circuits 143 , driving circuits 12 and switching circuits 11 is set to be the same as that of the current transformers. The number of L is equal. When there are multiple current transformers L, the primary winding of each current transformer L is connected in series with the AC power supply (the output end of the inverter circuit 141 ) in turn, and the secondary winding of each current transformer L is connected in series. A corresponding rectifier circuit 143 respectively supplies power to a corresponding drive circuit 12; one or more switch circuits 11 are connected in series or in parallel, and each drive circuit 12 is connected with a corresponding switch circuit 11 for controlling the corresponding The on-off of a switch circuit 11.
示意性的，在图6中，电流互感器一共有六个（L1、L2、L3、L4、L5、L6），驱动电路12对应也有六个（第一驱动电路121，第二驱动电路122，第三驱动电路123，第四驱动电路124，第五驱动电路125，第六驱动电路126），开关电路11对应有六个（第一开关电路111，第二开关电路112，第三开关电路113，第四开关电路114，第五开关电路115，第六开关电路116）。其中，第一开关电路111，第二开关电路112，第三开关电路113与负载3、正高压电源201形成正高压脉冲产生回路。第四开关电路114，第五开关电路115，第六开关电路116与负载3、负高压电源202形成负高压脉冲产生回路。每个电流互感器输出的交流电压，经过对应的整流电路143（图6中未示出）整流后，对应为一个驱动电路12供电，一个驱动电路12用于驱动一个开关电路11。Schematically, in FIG. 6, there are six current transformers (L1, L2, L3, L4, L5, L6), and there are six corresponding driving circuits 12 (the first driving circuit 121, the second driving circuit 122, The third driving circuit 123 , the fourth driving circuit 124 , the fifth driving circuit 125 , the sixth driving circuit 126 ), the switch circuits 11 correspond to six (the first switch circuit 111 , the second switch circuit 112 , the third switch circuit 113 ) , the fourth switch circuit 114, the fifth switch circuit 115, the sixth switch circuit 116). The first switch circuit 111 , the second switch circuit 112 , and the third switch circuit 113 , the load 3 and the positive high voltage power supply 201 form a positive high voltage pulse generating circuit. The fourth switch circuit 114 , the fifth switch circuit 115 , and the sixth switch circuit 116 form a negative high voltage pulse generating loop with the load 3 and the negative high voltage power supply 202 . The AC voltage output by each current transformer is rectified by the corresponding rectifier circuit 143 (not shown in FIG. 6 ), and then supplies power to one drive circuit 12 , and one drive circuit 12 is used to drive one switch circuit 11 .
图6中，光纤通信电路15有两个，分别为第一光纤通信电路151和第二光纤通信电路152，频率发生器131对应产生第一脉冲控制信号和第二脉冲控制信号。第一脉冲控制信号用于输入至第一驱动电路121、第二驱动电路122及第三驱动电路123的脉冲信号输入端；第二脉冲控制信号用于输入至第四驱动电路124、第五驱动电路125及第六驱动电路126的脉冲信号输入端。In FIG. 6, there are two optical fiber communication circuits 15, namely a first optical fiber communication circuit 151 and a second optical fiber communication circuit 152, and the frequency generator 131 generates a first pulse control signal and a second pulse control signal correspondingly. The first pulse control signal is used for input to the pulse signal input terminals of the first driving circuit 121, the second driving circuit 122 and the third driving circuit 123; the second pulse control signal is used for inputting the fourth driving circuit 124, the fifth driving circuit The pulse signal input terminal of the circuit 125 and the sixth driving circuit 126 .
在该实施例中，由于电流互感器L具有隔离作用，因此设置每个电流互感器L的初级绕组依次串联后，与逆变电路141的输出端连接的方式，不会造成各个电流互感器L的次级绕组之间互相干扰。通过这种连接方式，能够降低设置逆变电路141的数量，有利于降低脉冲发生设备的体积。In this embodiment, since the current transformers L have an isolation function, the primary windings of each current transformer L are set in series to be connected to the output end of the inverter circuit 141 in sequence, so as not to cause each current transformer L The secondary windings interfere with each other. Through this connection method, the number of inverter circuits 141 can be reduced, which is beneficial to reducing the volume of the pulse generating device.
在一实施例中，设置脉冲开关信号发生电路1还包括传输线18，传输线18串联多个电流互感器L的初级绕组。在一实施例中，由于脉冲信号具有丰富的谐波，谐波的尖峰电压是脉冲信号电压的2-3倍，可选用传输线的电压等级大于或等于20KV，以提高对驱动电路12的供电可靠性。In one embodiment, the set pulse switch signal generating circuit 1 further includes a transmission line 18 , and the transmission line 18 is connected in series with the primary windings of a plurality of current transformers L. In one embodiment, since the pulse signal has rich harmonics, the peak voltage of the harmonic is 2-3 times the voltage of the pulse signal, and the voltage level of the transmission line can be selected to be greater than or equal to 20KV to improve the reliability of the power supply to the driving circuit 12. sex.
本申请还进一步提出一种脉冲发生设备，请再次参阅图1，脉冲发生设备包括高压电源单元2以及脉冲开关信号发生电路1；脉冲开关信号发生电路1的开关电路11、高压电源单元2与负载3形成串联回路，开关电路11以通过通断切换产生高压脉冲作用在负载3上。The present application further proposes a pulse generating device. Please refer to FIG. 1 again. The pulse generating device includes a high-voltage power supply unit 2 and a pulse switching signal generating circuit 1; a switching circuit 11 of the pulse switching signal generating circuit 1, a high-voltage power supply unit 2 and a load 3 forms a series loop, and the switch circuit 11 acts on the load 3 by generating high-voltage pulses through on-off switching.
高压电源单元2有一个时，脉冲发生设备对应产生单极性高压脉冲。当高压电源单元2有两个，分别为正高压电源单元和负高压电源单元.正高压电源单元和负高压电源单元分别与一个开关电路11、负载3组成串联回路，以对应在负载3上产生正极性高压脉冲和负极性高压脉冲的双极性高压脉冲。When there is one high-voltage power supply unit 2, the pulse generating device generates unipolar high-voltage pulses correspondingly. When there are two high-voltage power supply units 2, they are positive high-voltage power supply unit and negative high-voltage power supply unit. Bipolar high voltage pulses of positive polarity high voltage pulses and negative polarity high voltage pulses.
进一步的，请再次参阅图3，还可以设置高压电源单元2包括高压电源以及与高压电源电连接的储能电容23；储能电容23与开关电路11、负载3形成串联回路；储能电容23用于存储高压电源的输出电能，并通过开关电路11向负载3提供脉冲电压。Further, please refer to FIG. 3 again, the high-voltage power supply unit 2 can also be set to include a high-voltage power supply and an energy storage capacitor 23 electrically connected to the high-voltage power supply; the energy storage capacitor 23 forms a series loop with the switch circuit 11 and the load 3; the energy storage capacitor 23 It is used to store the output power of the high-voltage power supply, and provide pulse voltage to the load 3 through the switch circuit 11 .
图6中，储能电容23包括第一储能电容231和第二储能电容232，第一储能电容231用于储存正高压电源201输出的直流电能，第二储能电容232用于储存负高压电源202输出的直流电能。In FIG. 6, the energy storage capacitor 23 includes a first energy storage capacitor 231 and a second energy storage capacitor 232. The first energy storage capacitor 231 is used to store the DC power output by the positive high voltage power supply 201, and the second energy storage capacitor 232 is used to store The DC power output by the negative high voltage power supply 202 .
通过储能电容23的设置，能够降低对高压直流电源的输出功率的要求，有效减少高压直流电源的体积和降低整机的材料成本。The setting of the energy storage capacitor 23 can reduce the requirement for the output power of the high-voltage DC power supply, effectively reduce the volume of the high-voltage DC power supply and reduce the material cost of the whole machine.
请参阅图3，在此，高压电源可以通过电网4电压经过隔离直流高压电路22获得。隔离直流高压电路22包括升压变压器、第一整流电路、第二逆变电路、第二整流电路以及PWM控制电路221，其中，PWM控制电路221与主控制器132连接。在一实施例中，升压变压器的升压比可以为1:15。在此，可以设置脉冲开关信号发生电路1还包括电压采集电路191和电流采集电路192，电压采集电路191用于采集所输出的高压脉冲的电压，电流采集电路192用于采集所输出的高压脉冲的电流。电压采集电路191、电流采集电路192分别均与主控制器132相连，若是电压监测值或电流监测值与预设值不同，主控制器132将控制隔离直流高压电路22的PWM控制电路221输出的PWM信号占空比，以对隔离直流高压电路22中的逆变电路的输出电压和电流进行调整。当PWM信号的占空比增大时，隔离直流高压电路22输出电压和电流升高。PWM信号占空比减小时，隔离直流高压电路22输出电压和电流降低。Please refer to FIG. 3 , where the high-voltage power supply can be obtained through the isolated DC high-voltage circuit 22 through the voltage of the grid 4 . The isolated DC high voltage circuit 22 includes a step-up transformer, a first rectifier circuit, a second inverter circuit, a second rectifier circuit and a PWM control circuit 221 , wherein the PWM control circuit 221 is connected to the main controller 132 . In one embodiment, the step-up ratio of the step-up transformer may be 1:15. Here, it can be set that the pulse switch signal generating circuit 1 further includes a voltage collection circuit 191 and a current collection circuit 192. The voltage collection circuit 191 is used to collect the voltage of the output high voltage pulse, and the current collection circuit 192 is used to collect the output high voltage pulse. the current. The voltage acquisition circuit 191 and the current acquisition circuit 192 are respectively connected to the main controller 132. If the voltage monitoring value or the current monitoring value is different from the preset value, the main controller 132 will control the output of the PWM control circuit 221 of the isolated DC high voltage circuit 22. The duty cycle of the PWM signal is used to adjust the output voltage and current of the inverter circuit in the isolated DC high voltage circuit 22 . When the duty cycle of the PWM signal increases, the output voltage and current of the isolated DC high voltage circuit 22 increase. When the duty cycle of the PWM signal decreases, the output voltage and current of the isolated DC high-voltage circuit 22 decrease.
需说明的是，本申请的脉冲开关信号发生电路和脉冲发生设备可以包括但不限于运用于医疗器械领域，也可以运用到其他领域。It should be noted that the pulse switch signal generating circuit and the pulse generating device of the present application may include, but are not limited to, application in the field of medical devices, and may also be applied in other fields.
虽然已参照几个典型实施方式描述了本申请，但应当理解，所用的术语是说明和示例性、而非限制性的术语。由于本申请能够以多种形式具体实施而不脱离发明的精神或实质，所以应当理解，上述实施方式不限于任何前述的细节，而应在随附权利要求所限定的精神和范围内广泛地解释，因此落入权利要求或其等效范围内的全部变化和改型都应为随附权利要求所涵盖。While the application has been described with reference to several exemplary embodiments, it is to be understood that the terminology used is of description and illustration, and not of limitation. Since the application can be embodied in many forms without departing from the spirit or essence of the invention, it is to be understood that the above-described embodiments are not limited to any of the foregoing details, but are to be construed broadly within the spirit and scope defined by the appended claims Therefore, all changes and modifications that come within the scope of the claims or their equivalents should be covered by the appended claims.

Claims (21)

  1. 一种脉冲开关信号发生电路，其特征在于，包括：A pulse switch signal generating circuit, characterized in that it includes:
    开关电路，所述开关电路通过通断切换输出脉冲开关信号； a switch circuit, the switch circuit outputs a pulse switch signal by switching on and off;
    驱动电路，所述驱动电路具有脉冲信号输入端、电源端以及驱动端；所述驱动端与所述开关电路的受控端连接，以用于控制所述开关电路的通断；a drive circuit, the drive circuit has a pulse signal input end, a power supply end and a drive end; the drive end is connected to the controlled end of the switch circuit for controlling the on-off of the switch circuit;
    脉冲控制电路，与所述驱动电路的脉冲信号输入端连接，所述脉冲控制电路用于输出脉冲控制信号；a pulse control circuit, connected to the pulse signal input end of the drive circuit, and the pulse control circuit is used for outputting the pulse control signal;
    驱动供电电路，所述驱动供电电路的输出端与所述驱动电路的电源端连接。A drive power supply circuit, the output end of the drive power supply circuit is connected with the power supply end of the drive circuit.
  2. 根据权利要求1所述的脉冲开关信号发生电路，其特征在于，所述脉冲控制电路包括频率发生器，所述频率发生器根据预置的参数发出至少一路的脉冲控制信号。The pulse switch signal generating circuit according to claim 1, wherein the pulse control circuit comprises a frequency generator, and the frequency generator sends out at least one pulse control signal according to preset parameters.
  3. 根据权利要求2所述的脉冲开关信号发生电路，其特征在于，所述脉冲控制电路还包括主控制器，所述主控制器与所述频率发生器电连接，以向所述频率发生器发送所述预置的参数，所述预置的参数包括可调整的脉冲频率、脉冲个数和占空比的至少之一。The pulse switch signal generating circuit according to claim 2, wherein the pulse control circuit further comprises a main controller, and the main controller is electrically connected with the frequency generator to send the signal to the frequency generator. The preset parameter includes at least one of adjustable pulse frequency, pulse number and duty cycle.
  4. 根据权利要求3所述的脉冲开关信号发生电路，其特征在于，所述主控制器还包括计数电路，所述计数电路与所述频率发生器的输出端电连接，以用于检测所述频率发生器所输出的脉冲的数量。The pulse switch signal generating circuit according to claim 3, wherein the main controller further comprises a counting circuit, and the counting circuit is electrically connected to the output end of the frequency generator for detecting the frequency The number of pulses output by the generator.
  5. 根据权利要求3所述的脉冲开关信号发生电路，其特征在于，所述脉冲开关信号发生电路具有人机交互组件；所述人机交互组件用于接收调节信号，所述调节信号用于对所述脉冲控制信号的脉冲个数、脉冲频率和占空比中的至少之一进行调节。The pulse switch signal generating circuit according to claim 3, wherein the pulse switch signal generating circuit has a human-computer interaction component; the human-computer interaction component is used to receive an adjustment signal, and the adjustment signal is used to At least one of the pulse number, pulse frequency and duty cycle of the pulse control signal is adjusted.
  6. 根据权利要求1至5中任意一项所述的脉冲开关信号发生电路，其特征在于，所述脉冲开关信号发生电路还包括光纤通信电路，所述光纤通信电路用于将所述脉冲控制信号以光能的形式发送至所述驱动电路的脉冲信号输入端。The pulse switch signal generating circuit according to any one of claims 1 to 5, wherein the pulse switch signal generating circuit further comprises an optical fiber communication circuit, and the optical fiber communication circuit is used for converting the pulse control signal into a The form of light energy is sent to the pulse signal input terminal of the driving circuit.
  7. 根据权利要求1至6中任意一项所述的脉冲开关信号发生电路，其特征在于，所述驱动供电电路包括依次串联的变压装置以及整流电路，所述变压装置的初级侧供交流电源连接，次级侧与所述整流电路连接，所述整流电路的输出端与所述驱动电路的电源端连接。The pulse switch signal generating circuit according to any one of claims 1 to 6, wherein the driving power supply circuit comprises a transformer device and a rectifier circuit which are connected in series in sequence, and the primary side of the transformer device supplies the AC power supply The secondary side is connected to the rectifier circuit, and the output end of the rectifier circuit is connected to the power source end of the drive circuit.
  8. 根据权利要求7所述的脉冲开关信号发生电路，其特征在于，所述变压装置包括电流互感器，所述电流互感器的初级绕组与所述交流电源连接，所述电流互感器的次级绕组输出交流电压，且与所述整流电路电连接。The pulse switch signal generating circuit according to claim 7, wherein the transformer device comprises a current transformer, the primary winding of the current transformer is connected to the AC power source, and the secondary winding of the current transformer is connected to the AC power source. The winding outputs an AC voltage and is electrically connected to the rectifier circuit.
  9. 根据权利要求8所述的脉冲开关信号发生电路，其特征在于，所述驱动供电电路还包括逆变电路，所述逆变电路的输入端供直流电源连接，所述逆变电路的输出端与所述电流互感器的初级绕组连接。The pulse switch signal generating circuit according to claim 8, wherein the driving power supply circuit further comprises an inverter circuit, the input end of the inverter circuit is connected to the DC power supply, and the output end of the inverter circuit is connected to the DC power supply. The primary winding of the current transformer is connected.
  10. 根据权利要求9所述的脉冲开关信号发生电路，其特征在于，所述驱动供电电路还包括电压调整电路，所述电压调整电路与所述整流电路的输出端连接，以将所述整流电路输出的直流电进行直流变换生成第一电压和第二电压；The pulse switch signal generating circuit according to claim 9, wherein the driving power supply circuit further comprises a voltage adjusting circuit, and the voltage adjusting circuit is connected to the output end of the rectifying circuit, so as to output the output of the rectifying circuit The direct current is converted to a direct current to generate a first voltage and a second voltage;
    所述第一电压与所述驱动电路的电源端连接；the first voltage is connected to the power supply terminal of the driving circuit;
    所述第二电压通过上拉电阻与所述驱动电路的脉冲信号输入端连接。The second voltage is connected to the pulse signal input end of the driving circuit through a pull-up resistor.
  11. 根据权利要求1至10中任意一项所述的脉冲开关信号发生电路，其特征在于，所述开关电路包括开关管；The pulse switch signal generating circuit according to any one of claims 1 to 10, wherein the switch circuit comprises a switch tube;
    所述开关电路还包括泄放电路，所述泄放电路连接在所述开关管的受控端与第二端之间；其中，所述开关管的第一端供高压电能输入，所述开关管的第二端供高压电能输出。The switch circuit further includes a discharge circuit, and the discharge circuit is connected between the controlled end and the second end of the switch tube; wherein, the first end of the switch tube is supplied with high-voltage power input, and the switch The second end of the tube is for outputting high-voltage electrical energy.
  12. 根据权利要求11所述的脉冲开关信号发生电路，其特征在于，所述开关电路还包括分压电路，所述分压电路具有电源输入端，以及分压输出端；The pulse switch signal generating circuit according to claim 11, wherein the switch circuit further comprises a voltage divider circuit, and the voltage divider circuit has a power input end and a voltage divider output end;
    所述分压电路的电源输入端供第三电源连接，所述分压输出端与所述开关管的第二端连接，以在所述开关管的受控端上的驱动电压低于第一电压时，使所述开关管的受控端和第二端之间的压差为负电压。The power input end of the voltage divider circuit is connected to a third power source, and the voltage divider output end is connected to the second end of the switch tube, so that the driving voltage on the controlled end of the switch tube is lower than the first voltage, the voltage difference between the controlled end and the second end of the switch tube is a negative voltage.
  13. 根据权利要求12所述的脉冲开关信号发生电路，其特征在于，所述分压电路包括分压电阻和稳压二极管；The pulse switch signal generating circuit according to claim 12, wherein the voltage dividing circuit comprises a voltage dividing resistor and a zener diode;
    所述稳压二极管的阳极接地；所述分压电阻的第一端为所述电源输入端，所述分压电阻的第二端与所述稳压二极管的阴极连接，以形成所述分压输出端。The anode of the zener diode is grounded; the first end of the voltage divider resistor is the power input end, and the second end of the voltage divider resistor is connected to the cathode of the zener diode to form the voltage divider output.
  14. 根据权利要求1至13任意一项所述的脉冲开关信号发生电路，其特征在于，所述开关电路包括一个或多个串联或并联连接的开关管；所述驱动电路对应有一个或多个，每一个所述驱动电路对应驱动控制一个或多个所述开关管的通断。The pulse switch signal generating circuit according to any one of claims 1 to 13, wherein the switch circuit comprises one or more switch tubes connected in series or in parallel; the drive circuit corresponds to one or more, Each of the driving circuits correspondingly drives and controls the on-off of one or more of the switch tubes.
  15. 根据权利要求1至14任意一项所述的脉冲开关信号发生电路，其特征在于，所述驱动供电电路有一个或多个，一个所述驱动供电电路对应为一个或多个所述驱动电路提供电源。The pulse switch signal generating circuit according to any one of claims 1 to 14, characterized in that, there are one or more drive power supply circuits, and one drive power supply circuit corresponds to one or more of the drive circuits to provide power supply.
  16. 根据权利要求1至15任意一项所述的脉冲开关信号发生电路，其特征在于，所述脉冲控制电路发出一个或多个脉冲控制信号，一个所述脉冲控制信号对应输出到一个或多个所述驱动电路的脉冲信号输入端。The pulse switch signal generating circuit according to any one of claims 1 to 15, wherein the pulse control circuit sends out one or more pulse control signals, and one of the pulse control signals is correspondingly output to one or more of the pulse control signals. The pulse signal input terminal of the drive circuit.
  17. 根据权利要求8至16任意一项所述的脉冲开关信号发生电路，其特征在于，所述电流互感器有1个或多个，在所述电流互感器有多个时，每个所述电流互感器的初级绕组依次串联与所述交流电源连接，每个所述电流互感器的次级绕组分别与所述整流电路连接。The pulse switch signal generating circuit according to any one of claims 8 to 16, wherein there are one or more current transformers, and when there are multiple current transformers, each current transformer The primary windings of the transformers are sequentially connected in series with the AC power supply, and the secondary windings of each of the current transformers are respectively connected with the rectifier circuit.
  18. 根据权利要求17所述的脉冲开关信号发生电路，其特征在于，所述电流互感器有1个或多个，所述整流电路、所述驱动电路和所述开关电路的数量均与所述电流互感器的数量相等，在所述电流互感器有多个时，每个所述电流互感器的初级绕组依次串联与所述交流电源连接，每个所述电流互感器的次级绕组分别通过一对应的所述整流电路分别为一对应的所述驱动电路供电；The pulse switch signal generating circuit according to claim 17, wherein there are one or more current transformers, and the number of the rectifier circuit, the drive circuit and the switch circuit is the same as that of the current The number of transformers is equal, and when there are multiple current transformers, the primary winding of each current transformer is connected in series with the AC power source in sequence, and the secondary winding of each current transformer passes through a The corresponding rectifier circuits respectively supply power to a corresponding drive circuit;
    1个或多个所述开关电路串联或并联连接，每个所述驱动电路与对应的一所述开关电路连接，以用于控制对应的一所述开关电路的通断。One or more of the switch circuits are connected in series or in parallel, and each of the drive circuits is connected to a corresponding one of the switch circuits for controlling the on-off of the corresponding one of the switch circuits.
  19. 根据权利要求18所述的脉冲开关信号发生电路，其特征在于，所述脉冲开关信号发生电路还包括传输线，所述传输线串联所述多个电流互感器的初级绕组；所述传输线的电压等级大于或等于20KV。The pulse switch signal generating circuit according to claim 18, wherein the pulse switch signal generating circuit further comprises a transmission line, the transmission line is connected in series with the primary windings of the multiple current transformers; the voltage level of the transmission line is greater than or equal to 20KV.
  20. 一种脉冲发生设备，其特征在于，包括高压电源单元以及如权利要求1至19任意一项所述的脉冲开关信号发生电路；A pulse generating device, characterized in that it comprises a high-voltage power supply unit and the pulse switch signal generating circuit according to any one of claims 1 to 19;
    所述脉冲开关信号发生电路的开关电路、所述高压电源单元与负载形成串联回路，所述开关电路以通过通断切换产生高压脉冲作用在所述负载上。The switch circuit of the pulse switch signal generating circuit, the high-voltage power supply unit and the load form a series loop, and the switch circuit acts on the load by generating high-voltage pulses through on-off switching.
  21. 根据权利要求20所述的脉冲发生设备，其特征在于，所述高压电源单元包括高压直流电源以及与所述高压直流电源电连接的储能电容；所述储能电容与所述开关电路、所述负载形成串联回路；The pulse generating device according to claim 20, wherein the high-voltage power supply unit comprises a high-voltage DC power supply and an energy storage capacitor electrically connected to the high-voltage DC power supply; the energy storage capacitor is connected to the switch circuit, the The load forms a series circuit;
    所述储能电容用于存储所述高压直流电源的输出电能，并通过所述开关电路向所述负载提供脉冲电压。The energy storage capacitor is used for storing the output electric energy of the high voltage direct current power supply, and provides a pulse voltage to the load through the switch circuit.
PCT/CN2022/085712 2021-04-15 2022-04-08 Pulse switching signal generating circuit and pulse generating device WO2022218213A1 (en)

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CN114900157B (en) * 2022-07-12 2022-09-20 深圳迈微医疗科技有限公司 Pulse generating circuit, pulse generator and medical equipment

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