WO2022211246A1 - Liquid injection device - Google Patents

Liquid injection device Download PDF

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Publication number
WO2022211246A1
WO2022211246A1 PCT/KR2022/001524 KR2022001524W WO2022211246A1 WO 2022211246 A1 WO2022211246 A1 WO 2022211246A1 KR 2022001524 W KR2022001524 W KR 2022001524W WO 2022211246 A1 WO2022211246 A1 WO 2022211246A1
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WO
WIPO (PCT)
Prior art keywords
catheter
needles
head
target
living body
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PCT/KR2022/001524
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French (fr)
Korean (ko)
Inventor
김준기
이상화
Original Assignee
재단법인 아산사회복지재단
울산대학교 산학협력단
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Application filed by 재단법인 아산사회복지재단, 울산대학교 산학협력단 filed Critical 재단법인 아산사회복지재단
Publication of WO2022211246A1 publication Critical patent/WO2022211246A1/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A61B10/04—Endoscopic instruments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34—Trocars; Puncturing needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes

Definitions

  • the present invention relates to a liquid flow injection device.
  • liquids drugs, various reagents for procedures or diagnosis, cell therapy agents, stem cells, etc.
  • insert the needle of the syringe into the tissue layer of the living body and then apply force to the syringe.
  • the liquid contained in the percussion syringe is injected into the tissue layer.
  • the depth of the needle inserted into the tissue layer is controlled by the force of a person's hand operating the syringe, it may be difficult to precisely control the depth of the needle for the tissue layer.
  • the injection amount of the liquid per unit time is insufficient, the injection amount of cells can be increased by increasing the diameter of the needle, but when the diameter of the needle increases, the adjustable depth of the needle inserted into the tissue layer may be reduced.
  • a needle hole by the syringe is generated in the living body, or because the length of the needle is long, it is not easy to move along the curved part of the living body, and the needle may be bent.
  • various layers such as epidermal layer, connective layer, muscle layer, mesothelial layer, and secretory layer (Urothelium, Lamina intestinal, Muscular layer, and Serosa) are distributed in the biological tissue layer within a thickness of several hundred micrometers. It is not easy to inject accurately.
  • the target of the living body is located in a very narrow space such as the bladder and the large intestine, as the bending radius and the bending space of the endoscope are limited, the needle provided in the head of the endoscope cannot be vertically incident on the target of the living body, so the needle There was a problem that the drug could not be effectively delivered to the target of the living body.
  • the present invention has been devised to solve the above problems, and an object of the present invention is to effectively deliver a liquid to a target of a living body through a needle even when the target of the living body is located in a very narrow space such as the bladder and the large intestine. It is intended to provide a liquid flow injection device.
  • a liquid flow injection device for solving the above-described problems is provided to be able to enter and exit the biopsy channel, the catheter providing a movement path of the liquid flow; and a needle array provided in the catheter and having a plurality of needles for injecting the liquid into a target of a living body, wherein the head of the catheter includes an inclined portion inclined with respect to the central axis of the catheter, a plurality of The needle may be provided to protrude from the inclined portion.
  • the plurality of needles may further include a deformation unit for deforming the head of the catheter to be inserted into the target of the living body.
  • the deformation unit a support member coupled to the head of the catheter; and a pair of manipulation wires connected to the support member to deform the shape of the catheter head, and oppositely tension or relax the pair of manipulation wires to deform the head shape of the catheter, a plurality of the The direction or depth in which the needle is inserted into the biological target can be adjusted.
  • the support member has a closed loop shape, and the head of the pair of manipulation wires may be coupled to both sides of the support member, respectively.
  • the needle array the base coupled to the inclined portion; and a plurality of needles disposed on the base.
  • the plurality of needles may be provided to protrude from the inclined portion to a predetermined height.
  • the liquid flow injection device includes: a catheter provided to be able to enter and exit the biopsy channel and provide a movement path of the liquid flow; and a needle array provided in the catheter and including a plurality of needles for injecting the liquid into a target of a living body, wherein the plurality of needles may be provided in a transverse direction with respect to the central axis of the catheter.
  • the plurality of needles may further include a deformation unit for deforming an area of the catheter provided with the plurality of needles to be inserted into the target of the living body.
  • the deformable unit may include a plurality of unit joint parts arranged in a line along the longitudinal direction of the catheter to enable mutual articulation, and may deform a region of the catheter according to the joint motion of the unit joint part.
  • the deformation unit may include a pair of catheter wires coupled to the catheter, and may deform a region of the catheter by tensioning or relaxing the pair of catheter wires to the contrary.
  • the deformation unit may include a support member coupled to an area of the catheter; and a pair of manipulation wires connected to the support member to deform the shape of a region of the catheter, and tension or relaxation of the pair of manipulation wires to change the shape of a region of the catheter, , it is possible to adjust the direction or depth in which the plurality of needles are inserted into the biological target.
  • the support member has a closed loop shape, and the head of the pair of manipulation wires may be coupled to both sides of the support member, respectively.
  • the needle array the base coupled to the catheter; and a plurality of needles disposed on the base.
  • the catheter may include an elastically deformable material.
  • the liquid flow injection device can effectively deliver a liquid flow to a living body target through a plurality of needles even when the living body target is located in a very narrow space such as the bladder and large intestine.
  • a plurality of needles are provided on an inclined portion inclinedly formed in the head of the catheter, so that the plurality of needles can be inclinedly inserted with respect to the target of the living body, the contact surface between the needle and the living tissue This increases, the possibility of backflow of the liquid from the needle is reduced, and the amount of liquid delivered from the needle to the living body can be improved.
  • FIG. 1 is a perspective view showing a liquid injection device according to a first embodiment of the present invention.
  • Figure 2 is an enlarged view showing the needle array according to the first embodiment of the present invention.
  • FIG 3 is a schematic view showing a state in which a plurality of needles of the liquid injection device according to the first embodiment of the present invention are inserted into the tissue layer.
  • FIGS. 4A and 4B are schematic diagrams illustrating examples of a deformable unit of the liquid flow injection device according to the first embodiment of the present invention.
  • FIG. 5 is a perspective view illustrating a liquid flow injection device according to a second embodiment of the present invention.
  • 6 to 8B are schematic diagrams showing various examples of the deformable unit of the liquid flow injection device according to the second embodiment of the present invention.
  • FIG. 1 is a perspective view showing a liquid injection device according to a first embodiment of the present invention
  • Figure 2 is an enlarged view showing a needle array according to the first embodiment of the present invention.
  • the liquid flow injection device includes a biopsy channel 10 , a catheter 40a and a needle array 50 .
  • the distal end of the catheter 40a facing the biological target and the distal end of the biopsy channel 10 are referred to as a catheter head and a biopsy channel head, respectively.
  • the biopsy channel 10 may be an endoscopic channel used for endoscopy/procedure, but is not limited thereto, and the biopsy channel 10 may be a separate channel for injecting a liquid into a target of a living body. Of course.
  • liquids include drugs, various reagents for procedure or diagnosis, cell therapy agents, stem cells, etc., and include liquids as well as semi-liquids (semi-solids such as hydrogels) surrounding the therapeutic agents/cells.
  • semi-liquids semi-liquids (semi-solids such as hydrogels) surrounding the therapeutic agents/cells.
  • a biopsy lamp 20 and a biopsy camera 30 may be provided at the head of the biopsy channel 10 .
  • One or more biopsy lamps 20 may be provided at the head of the biopsy channel 10 .
  • the biopsy lamp 20 may project a specific pattern capable of improving the identification of the target of the living body.
  • the specific pattern may be in the form of a grid. Accordingly, it is possible to provide the user with an image image of the target of the living body with improved identification by the specific pattern projected on the target of the living body.
  • the biopsy camera 30 may provide a video image of the target of the living body to the user by photographing the target of the living body from the head of the biopsy channel 10 .
  • the video image of the target of the living body may be displayed on a display (not shown) provided outside the living body.
  • the user may accurately inject the liquid into the target of the living body while checking the video image of the biopsy camera 30 .
  • the user may check the bleeding or leakage of the target of the living body in real time while checking the video image of the biopsy camera 30 .
  • the catheter 40a is provided to be in and out of the biopsy channel 10, and provides a movement path of the liquid.
  • the catheter 40a may adjust the length of entering and leaving the head of the biopsy channel 10 to adjust the depth of insertion into the target of the living body.
  • the head of the catheter 40a may include an inclined portion 41 formed to be inclined with respect to the central axis of the catheter 40a. Also, the inclined portion 41 may be inclined with respect to the central axis of the head of the biopsy channel 10 .
  • the head of the biopsy channel 10 or the head of the catheter 40a may be deformed, and the head of the catheter 40a to be described later by the deformation of the head of the biopsy channel 10 or the head of the catheter 40a.
  • the provided plurality of needles 52 may be inserted into the target of the living body.
  • the catheter 40a may include an elastically deformable material.
  • the needle array 50 is provided in the head of the catheter 40a, and includes a plurality of needles 52 for injecting a liquid into a target of a living body.
  • a plurality of needles 52 are provided to protrude from the inclined portion 41 formed in the head of the catheter (40a).
  • the plurality of needles 52 may be provided to protrude from the inclined portion 41 to a predetermined height. In other words, the plurality of needles 52 are provided to protrude from the inclined portion 41 at the same height. Accordingly, the plurality of needles 52 may be inserted into the target of the living body at the same depth.
  • the needle array 50 may include a plurality of needles 52 each coupled to the inclined portion 41 .
  • the angles of the plurality of needles 52 may be individually changed according to the change in the angle of the inclined portion 41 .
  • the needle array 50 may include a base 51 coupled to the inclined portion 41 and a plurality of needles 52 disposed on the base 51 .
  • the needle array 50 is provided in a bundle type in which the angle of the plurality of needles 52 is integrally changed according to the change in the angle of the base 51 . Accordingly, the angle of the plurality of needles 52 may be integrally changed according to the change in the angle of the inclined portion 41 .
  • FIG. 3 is a schematic diagram illustrating a state in which a plurality of needles of the liquid injection device according to the first embodiment of the present invention are inserted into a living body target.
  • the target of the living body is reached.
  • the user can accurately inject the liquid into the target of the living body while checking the video image of the biopsy camera 30 .
  • the user may check the bleeding or leakage of the target of the living body in real time while checking the video image of the biopsy camera 30 .
  • the user transforms the head of the biopsy channel 10 or the head of the catheter 40a in a direction in which the plurality of needles 52 are inserted into the target of the living body, so that the plurality of needles ( After the 52 is inserted into the target of the living body, the liquid flow is injected into the target of the living body through the plurality of needles 52 .
  • a plurality of needles 52 are provided on the inclined portion 41 formed to be inclined to the head of the catheter 40a, so that even with very little deformation of the head of the biopsy channel 10 or the head of the catheter 40a, a plurality of needles (52) can be inserted into the target of the living body.
  • the head of the biopsy channel 10 or the head of the catheter 40a is deformed very slightly, and the drug is injected through the plurality of needles 52 It can be effectively delivered to the target of the living body.
  • the plurality of needles 52 are provided on the inclined portion 41 formed to be inclined in the head of the catheter 40a, the plurality of needles 52 may be inserted inclined with respect to the target of the living body, so that the needle 52 and The contact surface between living tissues is increased, the possibility of backflow of the liquid from the needle 52 is reduced, and the amount of liquid transferred from the needle 52 to the living body can be improved.
  • FIGS. 4A and 4B are schematic diagrams illustrating examples of a deformable unit of the liquid flow injection device according to the first embodiment of the present invention.
  • the liquid injection device according to the first embodiment of the present invention is a deformation unit ( 60) may be further included.
  • the deformation unit 60 may include a support member 61 and a pair of manipulation wires 62 .
  • the support member 61 is coupled to the head of the catheter 40a.
  • the support member 61 may have a closed loop shape, for example, may be formed in a circular shape.
  • the support member 61 is connected to a pair of operating wires 62 to be described later.
  • a pair of operating wires 62 are connected to the support member 61 to deform the shape of the catheter 40a head. Specifically, by tensioning or relaxing the pair of manipulation wires 62 oppositely, the head shape of the catheter 40a is changed, and the direction or depth in which the plurality of needles 52 are inserted into the target of the living body can be adjusted. .
  • a pair of manipulation wires 62 will be defined as a first manipulation wire 62a and a second manipulation wire 62b connected to both sides of the support member 61 .
  • one side of the head of the catheter 40a is spaced apart from the target of the living body and The other side of the head of the catheter 40a approaches the target of the living body, and the head of the catheter 40a may be bent.
  • a plurality of needles 52 provided in the head of the catheter 40a may be inserted into the target of the living body.
  • the head of the catheter 40a may be bent. At this time, the plurality of needles 52 provided in the head of the catheter 40a may be discharged from the target of the living body.
  • FIG. 5 is a perspective view illustrating a liquid flow injection device according to a second embodiment of the present invention.
  • the liquid injection device includes a biopsy channel 10 , a catheter 40b and a needle array 50 , but unlike the first embodiment, a needle Array 50 may be provided transverse to the central axis of catheter 40b.
  • the plurality of needles 52 may be provided in a transverse direction with respect to the central axis of the catheter 40b. In other words, the plurality of needles 52 may be provided on the outer peripheral surface of the head of the catheter (40b).
  • the plurality of needles 52 may be provided to protrude from the catheter 40b at a predetermined height. Accordingly, the plurality of needles 52 may be inserted into the target of the living body at the same depth.
  • the needle array 50 may include a plurality of needles 52 each coupled to the catheter 40b.
  • the angles of the plurality of needles 52 may be individually changed according to the change in the angle of the inclined portion 41 .
  • the needle array 50 may include a base 51 coupled to the catheter 40b and a plurality of needles 52 disposed on the base 51 .
  • the needle array 50 is provided in a bundle type in which the angle of the plurality of needles 52 is integrally changed according to the change in the angle of the base 51 . Accordingly, the angle of the plurality of needles 52 may be integrally changed according to the change in the angle of the inclined portion 41 .
  • the target of the living body is reached.
  • the user can accurately inject the liquid into the target of the living body while checking the video image of the biopsy camera 30 .
  • the user may check the bleeding or leakage of the target of the living body in real time while checking the video image of the biopsy camera 30 .
  • the user deforms the head of the biopsy channel 10 or the head of the catheter 40b in a direction in which the plurality of needles 52 are inserted into the target of the living body, and the plurality of needles 52 are inserted into the target of the living body After that, the liquid flow is injected into the target of the living body through the plurality of needles 52 .
  • the plurality of needles 52 are provided in the transverse direction with respect to the central axis of the catheter 40b, so that even a very small deformation of the head of the biopsy channel 10 or the head of the catheter 40b, the plurality of needles 52 It can be inserted into the target of the living body.
  • the plurality of needles 52 are provided in the transverse direction with respect to the central axis of the catheter 40b, even when the target of the living body is located in a very narrow space such as the bladder and the large intestine, the head of the biopsy channel 10 or By very slightly deforming the head of the catheter 40b, the liquid flow can be effectively delivered to the target of the living body through the plurality of needles 52 .
  • 6 to 8B are schematic diagrams showing various examples of the deformable unit of the liquid flow injection device according to the second embodiment of the present invention.
  • the liquid injection device is a catheter 40b provided with a plurality of needles 52 so that the plurality of needles 52 are inserted into the target of the living body. It may include a deformation unit 60 that deforms an area of .
  • the deformation unit 60 may include a plurality of unit joint parts 63 .
  • the plurality of unit joint portions 63 may be arranged in a line along the longitudinal direction of the catheter 40b to enable mutual joint movement, and one region of the catheter 40b may be deformed according to the joint motion of the unit joint portion 63. have. At this time, the plurality of unit joint parts 63 may be jointly moved by tension or relaxation of a joint wire (not shown) penetrating and connecting the plurality of unit joint parts 63 .
  • the deformation unit 60 may include a pair of catheter wires 64 .
  • the pair of catheter wires 64 is coupled to the catheter 40b, and the pair of catheter wires 64a and 64b are tensioned or relaxed in opposite directions to deform an area of the catheter 40b.
  • a pair of catheter wires 64 will be defined as a first catheter wire 64a and a second catheter wire 64b connected to both sides of the catheter 40b.
  • the head of the catheter 40b when the first catheter wire 64a is tensioned and the second catheter wire 64b is relaxed, one side of the head of the catheter 40b is spaced apart from the target of the living body and the other side of the head of the catheter 40b is the body's In the form of approaching the target, the head of the catheter 40b may be bent.
  • the head of the catheter 40b may be bent.
  • a plurality of needles 52 provided in the head of the catheter 40b by bending and deforming the head of the catheter 40b into a desired shape with a pair of catheter wires 64 are inserted or inserted according to the target shape of the living body. can be emitted.
  • the deformation unit 60 may include a support member 61 and a pair of manipulation wires 62 .
  • the support member 61 is coupled to the head of the catheter 40b.
  • the support member 61 may have a closed loop shape, for example, may be formed in a circular shape.
  • the support member 61 is connected to a pair of operating wires 62 to be described later.
  • a pair of operating wires 62 are connected to the support member 61 to deform the shape of the catheter 40b head. Specifically, by tensioning or relaxing the pair of manipulation wires 62 oppositely, the head shape of the catheter 40b is changed, and the direction or depth in which the plurality of needles 52 are inserted into the target of the living body can be adjusted. .
  • a pair of manipulation wires 62 will be defined as a first manipulation wire 62a and a second manipulation wire 62b connected to both sides of the support member 61 .
  • one side of the head of the catheter 40b is spaced apart from the target of the living body and The other side of the head of the catheter 40b approaches the target of the living body, and the head of the catheter 40b may be bent.
  • the head of the catheter 40b may be bent.
  • the plurality of needles 52 provided in the head of the catheter 40b by bending the head of the catheter 40b may be inserted or discharged into the target of the living body.
  • the drug is injected into the target of the living body through the plurality of needles 52 . can be communicated effectively.
  • a plurality of needles 52 are provided on the inclined portion 41 formed to be inclined at the head of the catheter 40b, so that the plurality of needles 52 is a target of the living body. Since it can be inserted obliquely with respect to the needle 52, the contact surface between the needle 52 and the living tissue is increased, the possibility of backflow of the liquid from the needle 52 is reduced, and the amount of liquid transferred from the needle 52 to the living body is reduced. can be improved

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Abstract

The present invention relates to a liquid injection device comprising: a catheter which is provided to be retractable into and extendible from a biopsy channel and provides a movement path for a liquid; and a needle array which is provided in the catheter and includes a plurality of needles for injecting the liquid into a target of a living body, wherein the head of the catheter includes an inclined part which is formed to be inclined to the center axis of the catheter, and the plurality of needles are provided to protrude from the inclined part.

Description

액체류 주입 장치liquid injection device
본 발명은 액체류 주입 장치에 관한 것이다.The present invention relates to a liquid flow injection device.
일반적으로 액체류(약물, 시술이나 진단을 위한 다양한 시약, 세포치료제, 줄기 세포 등)를 생체의 조직층에 주입하기 위해서는, 주사기(Syringe)의 니들을 생체의 조직층에 삽입한 후, 주사기에 힘을 가해 주사기에 수용된 액체류를 조직층에 주입한다.In general, to inject liquids (drugs, various reagents for procedures or diagnosis, cell therapy agents, stem cells, etc.) into the tissue layer of the living body, insert the needle of the syringe into the tissue layer of the living body, and then apply force to the syringe. The liquid contained in the percussion syringe is injected into the tissue layer.
그런데, 조직층에 삽입되는 니들의 깊이는, 주사기를 조작하는 사람 손의 힘으로 조절되기 때문에, 조직층에 대한 니들의 정교한 깊이 조절이 어려울 수 있다.However, since the depth of the needle inserted into the tissue layer is controlled by the force of a person's hand operating the syringe, it may be difficult to precisely control the depth of the needle for the tissue layer.
또한, 단위 시간당 액체류의 주입량이 부족하면, 니들의 직경을 크게 하여 세포 주입량을 증가시킬 수 있지만, 니들의 직경이 커지면, 조직층에 삽입되는 니들의 조절 가능한 깊이(depth)가 줄어들 수 있다.In addition, if the injection amount of the liquid per unit time is insufficient, the injection amount of cells can be increased by increasing the diameter of the needle, but when the diameter of the needle increases, the adjustable depth of the needle inserted into the tissue layer may be reduced.
또한, 주사기를 통해 액체류를 생체의 조직층에 주입할 때, 주사기에 의한 니들 구멍이 생체에 발생되거나, 니들의 길이가 길기 때문에 생체의 굴곡 부위를 따라 이동이 쉽지 않고, 니들이 휘어버릴 수 있다.In addition, when injecting a liquid into a tissue layer of a living body through a syringe, a needle hole by the syringe is generated in the living body, or because the length of the needle is long, it is not easy to move along the curved part of the living body, and the needle may be bent.
특히, 생체 조직층에는 수백 마이크로 두께 내에 표피층, 결합층, 근육층, 중피층, 분비층(Urothelium, Lamina propria, Muscular layer 및 Serosa)등의 다양한 층이 분포되어 있는데, 주사기를 통해서는 원하는 조직층에 액체류를 정확하게 주입하기 쉽지 않다.In particular, various layers such as epidermal layer, connective layer, muscle layer, mesothelial layer, and secretory layer (Urothelium, Lamina propria, Muscular layer, and Serosa) are distributed in the biological tissue layer within a thickness of several hundred micrometers. It is not easy to inject accurately.
한편, 내시경의 헤드에 마련된 니들을 통해 생체의 타겟에 약물을 전달하는 다양한 방법이 존재하며, 이때, 시술자는 내시경을 통해 생체의 타겟을 보면서 니들을 통해 생체 내장의 타겟으로 약물을 전달할 수 있다. On the other hand, there are various methods of delivering a drug to a target of the living body through a needle provided in the head of the endoscope. At this time, the operator can deliver the drug to the target of the living body through the needle while viewing the target of the living body through the endoscope.
그런데, 생체의 타겟이 방광 및 대장 등과 같이 매우 좁은 공간에 위치하는 경우, 내시경의 굴곡 반경 및 굴곡 공간이 제한됨에 따라, 내시경의 헤드에 마련된 니들을 생체의 타겟에 수직하게 입사시킬 수 없으므로, 니들을 통해 약물을 생체의 타겟에 효과적으로 전달할 수 없는 문제점이 있었다.However, when the target of the living body is located in a very narrow space such as the bladder and the large intestine, as the bending radius and the bending space of the endoscope are limited, the needle provided in the head of the endoscope cannot be vertically incident on the target of the living body, so the needle There was a problem that the drug could not be effectively delivered to the target of the living body.
본 발명은 상술한 문제점을 해결하기 위하여 안출된 것으로, 본 발명의 목적은 생체의 타겟이 방광 및 대장 등과 같이 매우 좁은 공간에 위치하는 경우에도, 니들을 통해 액체류를 생체의 타겟에 효과적으로 전달할 수 있는 액체류 주입 장치를 제공하기 위한 것이다.The present invention has been devised to solve the above problems, and an object of the present invention is to effectively deliver a liquid to a target of a living body through a needle even when the target of the living body is located in a very narrow space such as the bladder and the large intestine. It is intended to provide a liquid flow injection device.
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본 발명이 해결하고자 하는 과제들은 이상에서 언급된 과제로 제한되지 않으며, 언급되지 않은 또 다른 과제들은 아래의 기재로부터 통상의 기술자에게 명확하게 이해될 수 있을 것이다.The problems to be solved by the present invention are not limited to the problems mentioned above, and other problems not mentioned will be clearly understood by those skilled in the art from the following description.
상술한 과제를 해결하기 위한 본 발명의 일 실시예에 따른 액체류 주입 장치는 생검 채널에 입출 가능하게 마련되고, 액체류의 이동 경로를 제공하는 카테터; 및 상기 카테터에 마련되어, 상기 액체류를 생체의 타겟에 주입하기 위한 복수의 니들을 구비하는 니들 어레이를 포함하고, 상기 카테터의 헤드는 상기 카테터의 중심축선에 대해 경사지게 형성된 경사부를 포함하며, 복수의 상기 니들은 상기 경사부로부터 돌출되도록 마련될 수 있다.A liquid flow injection device according to an embodiment of the present invention for solving the above-described problems is provided to be able to enter and exit the biopsy channel, the catheter providing a movement path of the liquid flow; and a needle array provided in the catheter and having a plurality of needles for injecting the liquid into a target of a living body, wherein the head of the catheter includes an inclined portion inclined with respect to the central axis of the catheter, a plurality of The needle may be provided to protrude from the inclined portion.
또한, 복수의 상기 니들이 생체의 타겟에 삽입되도록 상기 카테터의 헤드를 변형시키는 변형 유닛을 더 포함할 수 있다.In addition, the plurality of needles may further include a deformation unit for deforming the head of the catheter to be inserted into the target of the living body.
또한, 상기 변형 유닛은, 상기 카테터의 헤드에 결합되는 지지부재; 및 상기 지지부재에 연결되어, 상기 카테터 헤드의 형상을 변형시키는 한 쌍의 조작 와이어를 포함하고, 한 쌍의 상기 조작 와이어를 상반되게 인장 또는 이완시켜 상기 카테터의 헤드 형상을 변형시키며, 복수의 상기 니들이 생체 타겟에 삽입되는 방향 또는 깊이를 조절할 수 있다.In addition, the deformation unit, a support member coupled to the head of the catheter; and a pair of manipulation wires connected to the support member to deform the shape of the catheter head, and oppositely tension or relax the pair of manipulation wires to deform the head shape of the catheter, a plurality of the The direction or depth in which the needle is inserted into the biological target can be adjusted.
또한, 상기 지지부재는 폐루프 형태를 가지며, 한 쌍의 상기 조작 와이어의 헤드는, 각각 상기 지지부재의 양측에 결합될 수 있다.In addition, the support member has a closed loop shape, and the head of the pair of manipulation wires may be coupled to both sides of the support member, respectively.
또한, 상기 니들 어레이는, 상기 경사부에 결합되는 베이스; 및 상기 베이스에 배치되는 복수의 니들을 포함할 수 있다.In addition, the needle array, the base coupled to the inclined portion; and a plurality of needles disposed on the base.
또한, 복수의 상기 니들은 상기 경사부로부터 일정 높이로 돌출되게 마련될 수 있다. In addition, the plurality of needles may be provided to protrude from the inclined portion to a predetermined height.
본 발명의 다른 실시예에 따른 액체류 주입 장치는 생검 채널에 입출 가능하게 마련되고, 액체류의 이동 경로를 제공하는 카테터; 및 상기 카테터에 마련되어, 상기 액체류를 생체의 타겟에 주입하기 위한 복수의 니들을 구비하는 니들 어레이를 포함하고, 복수의 상기 니들은 상기 카테터의 중심축선에 대해 가로방향으로 마련될 수 있다.The liquid flow injection device according to another embodiment of the present invention includes: a catheter provided to be able to enter and exit the biopsy channel and provide a movement path of the liquid flow; and a needle array provided in the catheter and including a plurality of needles for injecting the liquid into a target of a living body, wherein the plurality of needles may be provided in a transverse direction with respect to the central axis of the catheter.
또한, 복수의 상기 니들이 생체의 타겟에 삽입되도록 복수의 상기 니들이 마련된 상기 카테터의 일 영역을 변형시키는 변형 유닛을 더 포함할 수 있다.In addition, the plurality of needles may further include a deformation unit for deforming an area of the catheter provided with the plurality of needles to be inserted into the target of the living body.
또한, 상기 변형 유닛은, 상호 관절 운동가능하게 상기 카테터의 길이방향을 따라 일렬 배치되는 복수의 단위관절부를 포함하며, 상기 단위관절부의 관절 운동에 따라 상기 카테터의 일 영역을 변형시킬 수 있다.In addition, the deformable unit may include a plurality of unit joint parts arranged in a line along the longitudinal direction of the catheter to enable mutual articulation, and may deform a region of the catheter according to the joint motion of the unit joint part.
또한, 상기 변형 유닛은, 상기 카테터에 결합되는 한 쌍의 카테터 와이어를 포함하며, 한 쌍의 상기 카테터 와이어를 상반되게 인장 또는 이완시켜 상기 카테터의 일 영역을 변형시킬 수 있다.In addition, the deformation unit may include a pair of catheter wires coupled to the catheter, and may deform a region of the catheter by tensioning or relaxing the pair of catheter wires to the contrary.
또한, 상기 변형 유닛은, 상기 카테터의 일 영역에 결합되는 지지부재; 및 상기 지지부재에 연결되어, 상기 카테터의 일 영역의 형상을 변형시키는 한 쌍의 조작 와이어를 포함하고, 한 쌍의 상기 조작 와이어를 상반되게 인장 또는 이완시켜 상기 카테터의 일 영역의 형상을 변형시키며, 복수의 상기 니들이 생체 타겟에 삽입되는 방향 또는 깊이를 조절할 수 있다.In addition, the deformation unit may include a support member coupled to an area of the catheter; and a pair of manipulation wires connected to the support member to deform the shape of a region of the catheter, and tension or relaxation of the pair of manipulation wires to change the shape of a region of the catheter, , it is possible to adjust the direction or depth in which the plurality of needles are inserted into the biological target.
또한, 상기 지지부재는 폐루프 형태를 가지며, 한 쌍의 상기 조작 와이어의 헤드는, 각각 상기 지지부재의 양측에 결합될 수 있다.In addition, the support member has a closed loop shape, and the head of the pair of manipulation wires may be coupled to both sides of the support member, respectively.
또한, 상기 니들 어레이는, 상기 카테터에 결합되는 베이스; 및 상기 베이스에 배치되는 복수의 니들을 포함할 수 있다.In addition, the needle array, the base coupled to the catheter; and a plurality of needles disposed on the base.
또한, 상기 카테터는 탄성변형가능한 재질을 포함할 수 있다.In addition, the catheter may include an elastically deformable material.
본 발명의 기타 구체적인 사항들은 상세한 설명 및 도면들에 포함되어 있다.Other specific details of the invention are included in the detailed description and drawings.
본 발명의 일 실시예에 따른 액체류 주입 장치는 생체의 타겟이 방광 및 대장 등과 같이 매우 좁은 공간에 위치하는 경우에도, 복수의 니들을 통해 액체류를 생체의 타겟에 효과적으로 전달할 수 있다.The liquid flow injection device according to an embodiment of the present invention can effectively deliver a liquid flow to a living body target through a plurality of needles even when the living body target is located in a very narrow space such as the bladder and large intestine.
또한, 본 발명의 일 실시예에 따른 액체류 주입 장치는 복수의 니들이 카테터의 헤드에 경사지게 형성된 경사부에 마련됨으로써, 복수의 니들이 생체의 타겟에 대해 경사지게 삽입될 수 있으므로, 니들 및 생체 조직 간에 접촉면이 증가하고, 니들에서의 액체류의 역류 가능성이 감소하고, 니들로부터 생체로 전달되는 액체류의 전달량을 향상시킬 수 있다.In addition, in the liquid injection device according to an embodiment of the present invention, a plurality of needles are provided on an inclined portion inclinedly formed in the head of the catheter, so that the plurality of needles can be inclinedly inserted with respect to the target of the living body, the contact surface between the needle and the living tissue This increases, the possibility of backflow of the liquid from the needle is reduced, and the amount of liquid delivered from the needle to the living body can be improved.
본 발명의 효과들은 이상에서 언급된 효과로 제한되지 않으며, 언급되지 않은 또 다른 효과들은 아래의 기재로부터 통상의 기술자에게 명확하게 이해될 수 있을 것이다.Effects of the present invention are not limited to the effects mentioned above, and other effects not mentioned will be clearly understood by those skilled in the art from the following description.
도 1은 본 발명의 제1실시예에 따른 액체류 주입 장치를 나타낸 사시도이다.1 is a perspective view showing a liquid injection device according to a first embodiment of the present invention.
도 2는 본 발명의 제1실시예에 따른 니들 어레이를 나타낸 확대도이다.Figure 2 is an enlarged view showing the needle array according to the first embodiment of the present invention.
도 3은 본 발명의 제1실시예에 따른 액체류 주입 장치의 복수의 니들이 조직층에 삽입된 상태를 나타낸 개략도이다.3 is a schematic view showing a state in which a plurality of needles of the liquid injection device according to the first embodiment of the present invention are inserted into the tissue layer.
도 4a, 도 4b는 본 발명의 제1실시예에 따른 액체류 주입 장치의 변형 유닛을 예시를 나타낸 개략도이다.4A and 4B are schematic diagrams illustrating examples of a deformable unit of the liquid flow injection device according to the first embodiment of the present invention.
도 5는 본 발명의 제2실시예에 따른 액체류 주입 장치를 나타낸 사시도이다.5 is a perspective view illustrating a liquid flow injection device according to a second embodiment of the present invention.
도 6 내지 도 8b는 본 발명의 제2실시예에 따른 액체류 주입 장치의 변형 유닛의 다양한 예시를 나타낸 개략도이다.6 to 8B are schematic diagrams showing various examples of the deformable unit of the liquid flow injection device according to the second embodiment of the present invention.
본 발명의 이점 및 특징, 그리고 그것들을 달성하는 방법은 첨부되는 도면과 함께 상세하게 후술되어 있는 실시예들을 참조하면 명확해질 것이다. 그러나, 본 발명은 이하에서 개시되는 실시예들에 제한되는 것이 아니라 서로 다른 다양한 형태로 구현될 수 있으며, 단지 본 실시예들은 본 발명의 개시가 완전하도록 하고, 본 발명이 속하는 기술 분야의 통상의 기술자에게 본 발명의 범주를 완전하게 알려주기 위해 제공되는 것이며, 본 발명은 청구항의 범주에 의해 정의될 뿐이다.Advantages and features of the present invention and methods of achieving them will become apparent with reference to the embodiments described below in detail in conjunction with the accompanying drawings. However, the present invention is not limited to the embodiments disclosed below, but may be implemented in various different forms, and only these embodiments allow the disclosure of the present invention to be complete, and those of ordinary skill in the art to which the present invention pertains. It is provided to fully inform those skilled in the art of the scope of the present invention, and the present invention is only defined by the scope of the claims.
본 명세서에서 사용된 용어는 실시예들을 설명하기 위한 것이며 본 발명을 제한하고자 하는 것은 아니다. 본 명세서에서, 단수형은 문구에서 특별히 언급하지 않는 한 복수형도 포함한다. 명세서에서 사용되는 "포함한다(comprises)" 및/또는 "포함하는(comprising)"은 언급된 구성요소 외에 하나 이상의 다른 구성요소의 존재 또는 추가를 배제하지 않는다. 명세서 전체에 걸쳐 동일한 도면 부호는 동일한 구성 요소를 지칭하며, "및/또는"은 언급된 구성요소들의 각각 및 하나 이상의 모든 조합을 포함한다. 비록 "제1", "제2" 등이 다양한 구성요소들을 서술하기 위해서 사용되나, 이들 구성요소들은 이들 용어에 의해 제한되지 않음은 물론이다. 이들 용어들은 단지 하나의 구성요소를 다른 구성요소와 구별하기 위하여 사용하는 것이다. 따라서, 이하에서 언급되는 제1 구성요소는 본 발명의 기술적 사상 내에서 제2 구성요소일 수도 있음은 물론이다.The terminology used herein is for the purpose of describing the embodiments and is not intended to limit the present invention. In this specification, the singular also includes the plural, unless specifically stated otherwise in the phrase. As used herein, “comprises” and/or “comprising” does not exclude the presence or addition of one or more other components in addition to the stated components. Like reference numerals refer to like elements throughout, and "and/or" includes each and every combination of one or more of the recited elements. Although "first", "second", etc. are used to describe various elements, these elements are not limited by these terms, of course. These terms are only used to distinguish one component from another. Therefore, it goes without saying that the first component mentioned below may be the second component within the spirit of the present invention.
다른 정의가 없다면, 본 명세서에서 사용되는 모든 용어(기술 및 과학적 용어를 포함)는 본 발명이 속하는 기술분야의 통상의 기술자에게 공통적으로 이해될 수 있는 의미로 사용될 수 있을 것이다. 또한, 일반적으로 사용되는 사전에 정의되어 있는 용어들은 명백하게 특별히 정의되어 있지 않는 한 이상적으로 또는 과도하게 해석되지 않는다.Unless otherwise defined, all terms (including technical and scientific terms) used herein will have the meaning commonly understood by those of ordinary skill in the art to which this invention belongs. In addition, terms defined in a commonly used dictionary are not to be interpreted ideally or excessively unless clearly specifically defined.
이하, 첨부된 도면을 참조하여 본 발명의 실시예를 상세하게 설명한다. Hereinafter, embodiments of the present invention will be described in detail with reference to the accompanying drawings.
도 1은 본 발명의 제1실시예에 따른 액체류 주입 장치를 나타낸 사시도이고, 도 2는 본 발명의 제1실시예에 따른 니들 어레이를 나타낸 확대도이다.1 is a perspective view showing a liquid injection device according to a first embodiment of the present invention, Figure 2 is an enlarged view showing a needle array according to the first embodiment of the present invention.
도 1 내지 도 2에 도시된 바와 같이, 본 발명의 제1실시예에 따른 액체류 주입 장치는 생검 채널(10), 카테터(40a) 및 니들 어레이(50)를 포함한다. 이하에서는 생체 타겟을 향하는 카테터(40a)의 말단부 및 생검 채널(10)의 말단부를 각각, 카테터 헤드 및 생검 채널 헤드라고 한다.1 to 2 , the liquid flow injection device according to the first embodiment of the present invention includes a biopsy channel 10 , a catheter 40a and a needle array 50 . Hereinafter, the distal end of the catheter 40a facing the biological target and the distal end of the biopsy channel 10 are referred to as a catheter head and a biopsy channel head, respectively.
생검 채널(10)은 내시경 검사/시술에 사용되는 내시경 채널이 적용될 수 있지만, 이에 한정되지는 아니하며, 생검 채널(10)은 액체류를 생체의 타겟으로 주입하기 위한 별도의 채널이 사용될 수도 있음은 물론이다.The biopsy channel 10 may be an endoscopic channel used for endoscopy/procedure, but is not limited thereto, and the biopsy channel 10 may be a separate channel for injecting a liquid into a target of a living body. Of course.
또한, 액체류는 약물, 시술이나 진단을 위한 다양한 시약, 세포치료제, 줄기 세포 등을 포함하고, 액체를 포함할 뿐만 아니라 치료약제/세포제를 감싸는 반액체(하이드로젤 등과 같은 반고체)를 포함할 수 있다.In addition, liquids include drugs, various reagents for procedure or diagnosis, cell therapy agents, stem cells, etc., and include liquids as well as semi-liquids (semi-solids such as hydrogels) surrounding the therapeutic agents/cells. can
생검 채널(10)의 헤드에는 생검 램프(20) 및 생검 카메라(30)가 마련될 수 있다.A biopsy lamp 20 and a biopsy camera 30 may be provided at the head of the biopsy channel 10 .
생검 램프(20)는 생검 채널(10)의 헤드에 하나 이상으로 마련될 수 있다. 생검 램프(20)는 생체의 타겟에 식별성을 향상시킬 수 있는 특정 패턴을 투영할 수 있다. 여기서, 특정 패턴은 그리드 형태일 수 있다. 따라서, 사용자에게 생체의 타겟에 투영된 특정 패턴에 의해 식별성이 향상된 생체의 타겟의 영상 이미지를 제공할 수 있다.One or more biopsy lamps 20 may be provided at the head of the biopsy channel 10 . The biopsy lamp 20 may project a specific pattern capable of improving the identification of the target of the living body. Here, the specific pattern may be in the form of a grid. Accordingly, it is possible to provide the user with an image image of the target of the living body with improved identification by the specific pattern projected on the target of the living body.
생검 카메라(30)는 생검 채널(10)의 헤드에서 생체의 타겟을 촬영하여 사용자에게 생체의 타겟에 대한 영상 이미지를 제공할 수 있다. 이때, 생체의 타겟에 대한 영상 이미지는 생체 외부에 마련된 디스플레이(미도시)에 표시될 수 있다. 사용자는 생검 카메라(30)의 영상 이미지를 확인하면서, 생체의 타겟에 액체류를 정확하게 주입할 수 있다. 또한, 사용자는 생검 카메라(30)의 영상 이미지를 확인하면서, 생체의 타겟의 출혈이나 누출을 실시간으로 확인할 수 있다.The biopsy camera 30 may provide a video image of the target of the living body to the user by photographing the target of the living body from the head of the biopsy channel 10 . In this case, the video image of the target of the living body may be displayed on a display (not shown) provided outside the living body. The user may accurately inject the liquid into the target of the living body while checking the video image of the biopsy camera 30 . In addition, the user may check the bleeding or leakage of the target of the living body in real time while checking the video image of the biopsy camera 30 .
카테터(40a)는 생검 채널(10)에 입출 가능하게 마련되고, 액체류의 이동 경로를 제공한다. 카테터(40a)는 생검 채널(10)의 헤드에서 입출되는 길이를 조절하여, 생체의 타겟에 삽입되는 깊이를 조절할 수 있다. The catheter 40a is provided to be in and out of the biopsy channel 10, and provides a movement path of the liquid. The catheter 40a may adjust the length of entering and leaving the head of the biopsy channel 10 to adjust the depth of insertion into the target of the living body.
카테터(40a)의 헤드는 카테터(40a)의 중심축선에 대해 경사지게 형성된 경사부(41)를 포함할 수 있다. 그리고, 경사부(41)는 생검 채널(10)의 헤드의 중심축선에 대해서도 경사지게 형성될 수 있다.The head of the catheter 40a may include an inclined portion 41 formed to be inclined with respect to the central axis of the catheter 40a. Also, the inclined portion 41 may be inclined with respect to the central axis of the head of the biopsy channel 10 .
한편, 생검 채널(10)의 헤드 또는 카테터(40a)의 헤드는 변형될 수 있으며, 이러한 생검 채널(10)의 헤드 또는 카테터(40a)의 헤드의 변형에 의해 후술할 카테터(40a)의 헤드에 마련된 복수의 니들(52)이 생체의 타겟에 삽입될 수 있다. 예를들면, 카테터(40a)는 탄성변형가능한 재질을 포함할 수 있다.On the other hand, the head of the biopsy channel 10 or the head of the catheter 40a may be deformed, and the head of the catheter 40a to be described later by the deformation of the head of the biopsy channel 10 or the head of the catheter 40a. The provided plurality of needles 52 may be inserted into the target of the living body. For example, the catheter 40a may include an elastically deformable material.
니들 어레이(50)는 카테터(40a)의 헤드에 마련되어, 액체류를 생체의 타겟에 주입하기 위한 복수의 니들(52)을 구비한다. The needle array 50 is provided in the head of the catheter 40a, and includes a plurality of needles 52 for injecting a liquid into a target of a living body.
본 실시예에서, 복수의 니들(52)은 카테터(40a)의 헤드에 형성된 경사부(41)로부터 돌출되도록 마련된다.In this embodiment, a plurality of needles 52 are provided to protrude from the inclined portion 41 formed in the head of the catheter (40a).
그리고, 복수의 니들(52)은 경사부(41)로부터 일정 높이로 돌출되도록 마련될 수 있다. 다시 말해, 복수의 니들(52)이 경사부(41)로부터 상호 동일한 높이로 돌출되도록 마련되는 것이다. 따라서, 복수의 니들(52)이 생체의 타겟에 상호 동일한 깊이로 삽입될 수 있다.In addition, the plurality of needles 52 may be provided to protrude from the inclined portion 41 to a predetermined height. In other words, the plurality of needles 52 are provided to protrude from the inclined portion 41 at the same height. Accordingly, the plurality of needles 52 may be inserted into the target of the living body at the same depth.
일 예로, 니들 어레이(50)는 경사부(41)에 각각 결합되는 복수의 니들(52)을 포함할 수 있다. 이 경우, 경사부(41)의 각도 변화에 따라 복수의 니들(52)의 각도가 개별로 변화될 수 있다.As an example, the needle array 50 may include a plurality of needles 52 each coupled to the inclined portion 41 . In this case, the angles of the plurality of needles 52 may be individually changed according to the change in the angle of the inclined portion 41 .
다른 예로, 니들 어레이(50)는 경사부(41)에 결합되는 베이스(51) 및 베이스(51)에 배치되는 복수의 니들(52)을 포함할 수 있다. 이 경우, 니들 어레이(50)는 베이스(51)의 각도 변화에 따라 복수의 니들(52)의 각도가 일체로 변화되는 번들형으로 마련된다. 따라서, 경사부(41)의 각도 변화에 따라 복수의 니들(52)의 각도가 일체로 변화될 수 있다.As another example, the needle array 50 may include a base 51 coupled to the inclined portion 41 and a plurality of needles 52 disposed on the base 51 . In this case, the needle array 50 is provided in a bundle type in which the angle of the plurality of needles 52 is integrally changed according to the change in the angle of the base 51 . Accordingly, the angle of the plurality of needles 52 may be integrally changed according to the change in the angle of the inclined portion 41 .
이하에서는 본 실시예에 따른 액체류 주입 장치의 복수의 니들(52)이 생체의 타겟에 삽입되어 액체류를 주입하는 작동예를 설명하기로 한다.Hereinafter, an operation example in which the plurality of needles 52 of the liquid flow injection device according to the present embodiment are inserted into a target of a living body to inject the liquid flow will be described.
도 3은 본 발명의 제1실시예에 따른 액체류 주입 장치의 복수의 니들이 생체의 타겟에 삽입된 상태를 나타낸 개략도이다.3 is a schematic diagram illustrating a state in which a plurality of needles of the liquid injection device according to the first embodiment of the present invention are inserted into a living body target.
우선, 사용자가 생검 채널(10), 카테터(40a) 및 니들 어레이(50)를 생체의 내부 기관에 투입한 후, 생체의 타겟에 도달시킨다.First, after the user inserts the biopsy channel 10 , the catheter 40a and the needle array 50 into the internal organs of the living body, the target of the living body is reached.
이 때, 사용자는 생검 카메라(30)의 영상 이미지를 확인하면서, 생체의 타겟에 액체류를 정확하게 주입할 수 있다. 또한, 사용자는 생검 카메라(30)의 영상 이미지를 확인하면서, 생체의 타겟의 출혈이나 누출을 실시간으로 확인할 수 있다.At this time, the user can accurately inject the liquid into the target of the living body while checking the video image of the biopsy camera 30 . In addition, the user may check the bleeding or leakage of the target of the living body in real time while checking the video image of the biopsy camera 30 .
다음으로, 도 3에 도시된 바와 같이, 사용자가 생검 채널(10)의 헤드 또는 카테터(40a)의 헤드를 복수의 니들(52)이 생체의 타겟에 삽입되는 방향으로 변형시켜서, 복수의 니들(52)이 생체의 타겟에 삽입된 후, 복수의 니들(52)을 통해 생체의 타겟에 액체류가 주입되게 한다.Next, as shown in FIG. 3, the user transforms the head of the biopsy channel 10 or the head of the catheter 40a in a direction in which the plurality of needles 52 are inserted into the target of the living body, so that the plurality of needles ( After the 52 is inserted into the target of the living body, the liquid flow is injected into the target of the living body through the plurality of needles 52 .
여기서, 복수의 니들(52)이 카테터(40a)의 헤드에 경사지게 형성된 경사부(41)에 마련됨으로써, 생검 채널(10)의 헤드 또는 카테터(40a)의 헤드를 매우 조금만 변형시켜도, 복수의 니들(52)이 생체의 타겟에 삽입될 수 있다. Here, a plurality of needles 52 are provided on the inclined portion 41 formed to be inclined to the head of the catheter 40a, so that even with very little deformation of the head of the biopsy channel 10 or the head of the catheter 40a, a plurality of needles (52) can be inserted into the target of the living body.
따라서, 생체의 타겟이 방광 및 대장 등과 같이 매우 좁은 공간에 위치하는 경우에도, 생검 채널(10)의 헤드 또는 카테터(40a)의 헤드를 매우 조금만 변형시켜서, 복수의 니들(52)을 통해 약물을 생체의 타겟에 효과적으로 전달할 수 있다.Therefore, even when the target of the living body is located in a very narrow space such as the bladder and the large intestine, the head of the biopsy channel 10 or the head of the catheter 40a is deformed very slightly, and the drug is injected through the plurality of needles 52 It can be effectively delivered to the target of the living body.
또한, 복수의 니들(52)이 카테터(40a)의 헤드에 경사지게 형성된 경사부(41)에 마련됨으로써, 복수의 니들(52)이 생체의 타겟에 대해 경사지게 삽입될 수 있으므로, 니들(52) 및 생체 조직 간에 접촉면이 증가하고, 니들(52)에서의 액체류의 역류 가능성이 감소하고, 니들(52)로부터 생체로 전달되는 액체류의 전달량을 향상시킬 수 있다.In addition, since the plurality of needles 52 are provided on the inclined portion 41 formed to be inclined in the head of the catheter 40a, the plurality of needles 52 may be inserted inclined with respect to the target of the living body, so that the needle 52 and The contact surface between living tissues is increased, the possibility of backflow of the liquid from the needle 52 is reduced, and the amount of liquid transferred from the needle 52 to the living body can be improved.
도 4a, 도 4b는 본 발명의 제1실시예에 따른 액체류 주입 장치의 변형 유닛을 예시를 나타낸 개략도이다.4A and 4B are schematic diagrams illustrating examples of a deformable unit of the liquid flow injection device according to the first embodiment of the present invention.
도 4a 내지 도 4b에 도시된 바와 같이, 본 발명의 제1실시예에 따른 액체류 주입 장치는 복수의 니들(52)이 생체의 타겟에 삽입되도록 카테터(40a)의 헤드를 변형시키는 변형 유닛(60)을 더 포함할 수 있다.As shown in Figures 4a to 4b, the liquid injection device according to the first embodiment of the present invention is a deformation unit ( 60) may be further included.
변형 유닛(60)은 지지부재(61) 및 한 쌍의 조작 와이어(62)를 포함할 수 있다.The deformation unit 60 may include a support member 61 and a pair of manipulation wires 62 .
지지부재(61)는 카테터(40a)의 헤드에 결합된다. 이러한 지지부재(61)는 폐루프 형태를 가질 수 있는데, 예를들면, 원형으로 형성될 수 있다. 지지부재(61)는 후술할 한 쌍의 조작 와이어(62)와 연결된다.The support member 61 is coupled to the head of the catheter 40a. The support member 61 may have a closed loop shape, for example, may be formed in a circular shape. The support member 61 is connected to a pair of operating wires 62 to be described later.
한 쌍의 조작 와이어(62)는 지지부재(61)에 연결되어, 카테터(40a) 헤드의 형상을 변형시킨다. 구체적으로, 한 쌍의 조작 와이어(62)를 상반되게 인장 또는 이완시켜, 카테터(40a)의 헤드 형상을 변형시키며, 복수의 니들(52)이 생체의 타겟에 삽입되는 방향 또는 깊이를 조절할 수 있다.A pair of operating wires 62 are connected to the support member 61 to deform the shape of the catheter 40a head. Specifically, by tensioning or relaxing the pair of manipulation wires 62 oppositely, the head shape of the catheter 40a is changed, and the direction or depth in which the plurality of needles 52 are inserted into the target of the living body can be adjusted. .
이하에서는 복수의 조작 와이어(62)가 한 쌍인 경우, 한 쌍의 조작 와이어(62)에 의해 카테터(40a) 헤드의 형상이 변형되는 예시를 설명하기로 한다. 설명 편의상 한 쌍의 조작 와이어(62)를 지지부재(61)의 양측에 연결된 제1조작 와이어(62a)와 제2조작 와이어(62b)로 정의하기로 한다. Hereinafter, when the plurality of manipulation wires 62 are a pair, an example in which the shape of the catheter 40a head is deformed by the pair of manipulation wires 62 will be described. For convenience of description, a pair of manipulation wires 62 will be defined as a first manipulation wire 62a and a second manipulation wire 62b connected to both sides of the support member 61 .
일예로, 도 4a 내지 도 4b에 도시된 바와 같이, 제1조작 와이어(62a)를 인장시키고 제2조작 와이어(62b)를 이완시키면, 카테터(40a)의 헤드의 일측은 생체의 타겟에서 이격하고 카테터(40a)의 헤드의 타측은 생체의 타겟에 접근하는 형태로, 카테터(40a)의 헤드가 벤딩될 수 있다. 이때, 카테터(40a)의 헤드에 마련된 복수의 니들(52)이 생체의 타겟에 삽입 될 수 있다.For example, as shown in FIGS. 4a to 4b, when the first manipulation wire 62a is tensioned and the second manipulation wire 62b is relaxed, one side of the head of the catheter 40a is spaced apart from the target of the living body and The other side of the head of the catheter 40a approaches the target of the living body, and the head of the catheter 40a may be bent. At this time, a plurality of needles 52 provided in the head of the catheter 40a may be inserted into the target of the living body.
다른 예로, 제1조작 와이어(62a)를 이완시키고 제2조작 와이어(62b)를 인장시키면, 카테터(40a)의 헤드의 일측은 생체의 타겟에 접근하고 카테터(40a)의 헤드의 타측은 생체의 타겟에 이격하는 형태로, 카테터(40a)의 헤드가 벤딩될 수 있다. 이때, 카테터(40a)의 헤드에 마련된 복수의 니들(52)이 생체의 타겟에서 배출 될 수 있다.As another example, when the first manipulating wire 62a is relaxed and the second manipulating wire 62b is tensioned, one side of the head of the catheter 40a approaches the target of the living body, and the other side of the head of the catheter 40a is of the living body. In a form spaced apart from the target, the head of the catheter 40a may be bent. At this time, the plurality of needles 52 provided in the head of the catheter 40a may be discharged from the target of the living body.
도 5는 본 발명의 제2실시예에 따른 액체류 주입 장치를 나타낸 사시도이다.5 is a perspective view illustrating a liquid flow injection device according to a second embodiment of the present invention.
도 5에 도시된 바와 같이, 본 발명의 제2실시예에 따른 액체류 주입 장치는 생검 채널(10), 카테터(40b) 및 니들 어레이(50)를 포함하되, 제1실시예와 달리, 니들 어레이(50)가 카테터(40b)의 중심축선에 대해 가로방향으로 마련될 수 있다.As shown in FIG. 5 , the liquid injection device according to the second embodiment of the present invention includes a biopsy channel 10 , a catheter 40b and a needle array 50 , but unlike the first embodiment, a needle Array 50 may be provided transverse to the central axis of catheter 40b.
즉, 본 실시예에서, 복수의 니들(52)은 카테터(40b)의 중심축선에 대해 가로방향으로 마련될 수 있다. 다시 말해, 복수의 니들(52)은 카테터(40b)의 헤드의 외주면에 마련될 수 있다.That is, in this embodiment, the plurality of needles 52 may be provided in a transverse direction with respect to the central axis of the catheter 40b. In other words, the plurality of needles 52 may be provided on the outer peripheral surface of the head of the catheter (40b).
복수의 니들(52)은 카테터(40b)로부터 일정 높이로 돌출되도록 마련될 수 있다. 따라서, 복수의 니들(52)이 생체의 타겟에 상호 동일한 깊이로 삽입될 수 있다.The plurality of needles 52 may be provided to protrude from the catheter 40b at a predetermined height. Accordingly, the plurality of needles 52 may be inserted into the target of the living body at the same depth.
일 예로, 니들 어레이(50)는 카테터(40b)에 각각 결합되는 복수의 니들(52)을 포함할 수 있다. 이 경우, 경사부(41)의 각도 변화에 따라 복수의 니들(52)의 각도가 개별로 변화될 수 있다.As an example, the needle array 50 may include a plurality of needles 52 each coupled to the catheter 40b. In this case, the angles of the plurality of needles 52 may be individually changed according to the change in the angle of the inclined portion 41 .
다른 예로, 니들 어레이(50)는 카테터(40b)에 결합되는 베이스(51) 및 베이스(51)에 배치되는 복수의 니들(52)을 포함할 수 있다. 이 경우, 니들 어레이(50)는 베이스(51)의 각도 변화에 따라 복수의 니들(52)의 각도가 일체로 변화되는 번들형으로 마련된다. 따라서, 경사부(41)의 각도 변화에 따라 복수의 니들(52)의 각도가 일체로 변화될 수 있다.As another example, the needle array 50 may include a base 51 coupled to the catheter 40b and a plurality of needles 52 disposed on the base 51 . In this case, the needle array 50 is provided in a bundle type in which the angle of the plurality of needles 52 is integrally changed according to the change in the angle of the base 51 . Accordingly, the angle of the plurality of needles 52 may be integrally changed according to the change in the angle of the inclined portion 41 .
이하에서는 본 실시예에 따른 액체류 주입 장치의 복수의 니들(52)이 생체의 타겟에 삽입되어 액체류를 주입하는 작동예를 설명하기로 한다.Hereinafter, an operation example in which the plurality of needles 52 of the liquid flow injection device according to the present embodiment are inserted into a target of a living body to inject the liquid flow will be described.
우선, 사용자가 생검 채널(10), 카테터(40b) 및 니들 어레이(50)를 생체의 내부 기관에 투입한 후, 생체의 타겟에 도달시킨다.First, after the user inserts the biopsy channel 10 , the catheter 40b and the needle array 50 into the internal organs of the living body, the target of the living body is reached.
이 때, 사용자는 생검 카메라(30)의 영상 이미지를 확인하면서, 생체의 타겟에 액체류를 정확하게 주입할 수 있다. 또한, 사용자는 생검 카메라(30)의 영상 이미지를 확인하면서, 생체의 타겟의 출혈이나 누출을 실시간으로 확인할 수 있다.At this time, the user can accurately inject the liquid into the target of the living body while checking the video image of the biopsy camera 30 . In addition, the user may check the bleeding or leakage of the target of the living body in real time while checking the video image of the biopsy camera 30 .
다음으로, 사용자가 생검 채널(10)의 헤드 또는 카테터(40b)의 헤드를 복수의 니들(52)이 생체의 타겟에 삽입되는 방향으로 변형시켜서, 복수의 니들(52)이 생체의 타겟에 삽입된 후, 복수의 니들(52)을 통해 생체의 타겟에 액체류가 주입되게 한다.Next, the user deforms the head of the biopsy channel 10 or the head of the catheter 40b in a direction in which the plurality of needles 52 are inserted into the target of the living body, and the plurality of needles 52 are inserted into the target of the living body After that, the liquid flow is injected into the target of the living body through the plurality of needles 52 .
여기서, 복수의 니들(52)이 카테터(40b)의 중심축선에 대해 가로방향으로 마련됨으로써, 생검 채널(10)의 헤드 또는 카테터(40b)의 헤드를 매우 조금만 변형시켜도, 복수의 니들(52)이 생체의 타겟에 삽입될 수 있다.Here, the plurality of needles 52 are provided in the transverse direction with respect to the central axis of the catheter 40b, so that even a very small deformation of the head of the biopsy channel 10 or the head of the catheter 40b, the plurality of needles 52 It can be inserted into the target of the living body.
따라서, 복수의 니들(52)이 카테터(40b)의 중심축선에 대해 가로방향으로 마련됨으로써, 생체의 타겟이 방광 및 대장 등과 같이 매우 좁은 공간에 위치하는 경우에도, 생검 채널(10)의 헤드 또는 카테터(40b)의 헤드를 매우 조금만 변형시켜서, 복수의 니들(52)을 통해 액체류를 생체의 타겟에 효과적으로 전달할 수 있다.Therefore, since the plurality of needles 52 are provided in the transverse direction with respect to the central axis of the catheter 40b, even when the target of the living body is located in a very narrow space such as the bladder and the large intestine, the head of the biopsy channel 10 or By very slightly deforming the head of the catheter 40b, the liquid flow can be effectively delivered to the target of the living body through the plurality of needles 52 .
도 6 내지 도 8b는 본 발명의 제2실시예에 따른 액체류 주입 장치의 변형 유닛의 다양한 예시를 나타낸 개략도이다.6 to 8B are schematic diagrams showing various examples of the deformable unit of the liquid flow injection device according to the second embodiment of the present invention.
도 6 내지 도 8b에 도시된 바와 같이, 본 발명의 제2실시예에 따른 액체류 주입 장치는 복수의 니들(52)이 생체의 타겟에 삽입되도록 복수의 니들(52)이 마련된 카테터(40b)의 일 영역을 변형시키는 변형 유닛(60)을 포함할 수 있다.6 to 8b, the liquid injection device according to the second embodiment of the present invention is a catheter 40b provided with a plurality of needles 52 so that the plurality of needles 52 are inserted into the target of the living body. It may include a deformation unit 60 that deforms an area of .
도 6을 참조하면, 변형 유닛(60)은 복수의 단위관절부(63)를 포함할 수 있다.Referring to FIG. 6 , the deformation unit 60 may include a plurality of unit joint parts 63 .
복수의 단위관절부(63)는 상호 관절 운동가능하게 카테터(40b)의 길이방향을 따라 일렬 배치될 수 있으며, 이러한 단위관절부(63)의 관절 운동에 따라 카테터(40b)의 일 영역을 변형시킬 수 있다. 이 때, 복수의 단위관절부(63)는 복수의 단위관절부(63)를 관통 및 연결하는 관절와이어(미도시)의 인장 또는 이완에 의해 관절 운동될 수 있다.The plurality of unit joint portions 63 may be arranged in a line along the longitudinal direction of the catheter 40b to enable mutual joint movement, and one region of the catheter 40b may be deformed according to the joint motion of the unit joint portion 63. have. At this time, the plurality of unit joint parts 63 may be jointly moved by tension or relaxation of a joint wire (not shown) penetrating and connecting the plurality of unit joint parts 63 .
도 7을 참조하면, 변형 유닛(60)은 한 쌍의 카테터 와이어(64)를 포함할 수 있다.Referring to FIG. 7 , the deformation unit 60 may include a pair of catheter wires 64 .
한 쌍의 카테터 와이어(64)는 카테터(40b)에 결합되며, 한 쌍의 상기 카테터 와이어(64a, 64b)를 상반되게 인장 또는 이완시켜, 카테터(40b)의 일 영역을 변형시킬 수 있다.The pair of catheter wires 64 is coupled to the catheter 40b, and the pair of catheter wires 64a and 64b are tensioned or relaxed in opposite directions to deform an area of the catheter 40b.
이하에서는 한 쌍의 카테터 와이어(64)에 의해 카테터(40b) 헤드의 형상이 변형되는 예시를 설명하기로 한다. 설명의 편의상, 한 쌍의 카테터 와이어(64)를 카테터(40b)의 양측에 연결된 제1카테터 와이어(64a)와 제2카테터 와이어(64b)로 정의하기로 한다. Hereinafter, an example in which the shape of the catheter 40b head is deformed by a pair of catheter wires 64 will be described. For convenience of description, a pair of catheter wires 64 will be defined as a first catheter wire 64a and a second catheter wire 64b connected to both sides of the catheter 40b.
일예로, 제1카테터 와이어(64a)를 인장시키고 제2카테터 와이어(64b)를 이완시키면, 카테터(40b)의 헤드의 일측은 생체의 타겟에서 이격하고 카테터(40b)의 헤드의 타측은 생체의 타겟에 접근하는 형태로, 카테터(40b)의 헤드가 벤딩될 수 있다.For example, when the first catheter wire 64a is tensioned and the second catheter wire 64b is relaxed, one side of the head of the catheter 40b is spaced apart from the target of the living body and the other side of the head of the catheter 40b is the body's In the form of approaching the target, the head of the catheter 40b may be bent.
다른 예로, 제1카테터 와이어(64a)를 이완시키고 제2카테터 와이어(64b)를 인장시키면, 카테터(40b)의 헤드의 일측은 생체의 타겟에 접근하고 카테터(40b)의 헤드의 타측은 생체의 타겟에 이격하는 형태로, 카테터(40b)의 헤드가 벤딩될 수 있다.As another example, when the first catheter wire 64a is relaxed and the second catheter wire 64b is tensioned, one side of the head of the catheter 40b approaches the target of the living body, and the other side of the head of the catheter 40b is the body of the living body. In a form spaced apart from the target, the head of the catheter 40b may be bent.
이와 같이, 한 쌍의 카테터 와이어(64)로 카테터(40b)의 헤드를 원하는 형태로 벤딩 변형시켜에 의해 카테터(40b)의 헤드에 마련된 복수의 니들(52)이 생체의 타겟 형상에 맞추어 삽입 또는 배출될 수 있다.In this way, a plurality of needles 52 provided in the head of the catheter 40b by bending and deforming the head of the catheter 40b into a desired shape with a pair of catheter wires 64 are inserted or inserted according to the target shape of the living body. can be emitted.
도 8a 내지 도 8b를 참조하면, 변형 유닛(60)은 지지부재(61) 및 한 쌍의 조작 와이어(62)를 포함할 수 있다.8A to 8B , the deformation unit 60 may include a support member 61 and a pair of manipulation wires 62 .
지지부재(61)는 카테터(40b)의 헤드에 결합된다. 이러한 지지부재(61)는 폐루프 형태를 가질 수 있는데, 예를들면, 원형으로 형성될 수 있다. 지지부재(61)는 후술할 한 쌍의 조작 와이어(62)와 연결된다.The support member 61 is coupled to the head of the catheter 40b. The support member 61 may have a closed loop shape, for example, may be formed in a circular shape. The support member 61 is connected to a pair of operating wires 62 to be described later.
한 쌍의 조작 와이어(62)는 지지부재(61)에 연결되어, 카테터(40b) 헤드의 형상을 변형시킨다. 구체적으로, 한 쌍의 조작 와이어(62)를 상반되게 인장 또는 이완시켜, 카테터(40b)의 헤드 형상을 변형시키며, 복수의 니들(52)이 생체의 타겟에 삽입되는 방향 또는 깊이를 조절할 수 있다.A pair of operating wires 62 are connected to the support member 61 to deform the shape of the catheter 40b head. Specifically, by tensioning or relaxing the pair of manipulation wires 62 oppositely, the head shape of the catheter 40b is changed, and the direction or depth in which the plurality of needles 52 are inserted into the target of the living body can be adjusted. .
이하에서는 복수의 조작 와이어(62)가 한 쌍인 경우, 한 쌍의 조작 와이어(62)에 의해 카테터(40b) 헤드의 형상이 변형되는 예시를 설명하기로 한다. 설명 편의상 한 쌍의 조작 와이어(62)를 지지부재(61)의 양측에 연결된 제1조작 와이어(62a)와 제2조작 와이어(62b)로 정의하기로 한다. Hereinafter, when the plurality of manipulation wires 62 are a pair, an example in which the shape of the catheter 40b head is deformed by the pair of manipulation wires 62 will be described. For convenience of description, a pair of manipulation wires 62 will be defined as a first manipulation wire 62a and a second manipulation wire 62b connected to both sides of the support member 61 .
일예로, 도 8a 내지 도 8b에 도시된 바와 같이, 제1조작 와이어(62a)를 인장시키고 제2조작 와이어(62b)를 이완시키면, 카테터(40b)의 헤드의 일측은 생체의 타겟에서 이격하고 카테터(40b)의 헤드의 타측은 생체의 타겟에 접근하는 형태로, 카테터(40b)의 헤드가 벤딩될 수 있다.For example, as shown in FIGS. 8a to 8b, when the first manipulation wire 62a is tensioned and the second manipulation wire 62b is relaxed, one side of the head of the catheter 40b is spaced apart from the target of the living body and The other side of the head of the catheter 40b approaches the target of the living body, and the head of the catheter 40b may be bent.
다른 예로, 제1조작 와이어(62a)를 이완시키고 제2조작 와이어(62b)를 인장시키면, 카테터(40b)의 헤드의 일측은 생체의 타겟에 접근하고 카테터(40b)의 헤드의 타측은 생체의 타겟에 이격하는 형태로, 카테터(40b)의 헤드가 벤딩될 수 있다.As another example, when the first manipulating wire 62a is relaxed and the second manipulating wire 62b is tensioned, one side of the head of the catheter 40b approaches the target of the living body and the other side of the head of the catheter 40b is of the living body. In a form spaced apart from the target, the head of the catheter 40b may be bent.
이와 같이, 카테터(40b)의 헤드의 벤딩에 의해 카테터(40b)의 헤드에 마련된 복수의 니들(52)이 생체의 타겟에 삽입 또는 배출될 수 있다.In this way, the plurality of needles 52 provided in the head of the catheter 40b by bending the head of the catheter 40b may be inserted or discharged into the target of the living body.
본 발명에 따르면, 본 발명의 일 실시예에 따른 액체류 주입 장치는 생체의 타겟이 방광 및 대장 등과 같이 매우 좁은 공간에 위치하는 경우에도, 복수의 니들(52)을 통해 약물을 생체의 타겟에 효과적으로 전달할 수 있다.According to the present invention, in the liquid injection device according to an embodiment of the present invention, even when the target of the living body is located in a very narrow space such as the bladder and the large intestine, the drug is injected into the target of the living body through the plurality of needles 52 . can be communicated effectively.
또한, 본 발명의 일 실시예에 따른 액체류 주입 장치는 복수의 니들(52)이 카테터(40b)의 헤드에 경사지게 형성된 경사부(41)에 마련됨으로써, 복수의 니들(52)이 생체의 타겟에 대해 경사지게 삽입될 수 있으므로, 니들(52) 및 생체 조직 간에 접촉면이 증가하고, 니들(52)에서의 액체류의 역류 가능성이 감소하고, 니들(52)로부터 생체로 전달되는 액체류의 전달량을 향상시킬 수 있다.In addition, in the liquid injection device according to an embodiment of the present invention, a plurality of needles 52 are provided on the inclined portion 41 formed to be inclined at the head of the catheter 40b, so that the plurality of needles 52 is a target of the living body. Since it can be inserted obliquely with respect to the needle 52, the contact surface between the needle 52 and the living tissue is increased, the possibility of backflow of the liquid from the needle 52 is reduced, and the amount of liquid transferred from the needle 52 to the living body is reduced. can be improved
이상, 첨부된 도면을 참조로 하여 본 발명의 실시예를 설명하였지만, 본 발명이 속하는 기술분야의 통상의 기술자는 본 발명이 그 기술적 사상이나 필수적인 특징을 변경하지 않고서 다른 구체적인 형태로 실시될 수 있다는 것을 이해할 수 있을 것이다. 그러므로, 이상에서 기술한 실시예들은 모든 면에서 예시적인 것이며, 제한적이 아닌 것으로 이해해야만 한다. As mentioned above, although embodiments of the present invention have been described with reference to the accompanying drawings, those skilled in the art to which the present invention pertains can realize that the present invention can be embodied in other specific forms without changing its technical spirit or essential features. you will be able to understand Therefore, it should be understood that the embodiments described above are illustrative in all respects and not restrictive.

Claims (15)

  1. 생검 채널에 입출 가능하게 마련되고, 액체류의 이동 경로를 제공하는 카테터; 및a catheter provided to be able to enter and exit the biopsy channel and provide a movement path for the liquid; and
    상기 카테터에 마련되어, 상기 액체류를 생체의 타겟에 주입하기 위한 복수의 니들을 구비하는 니들 어레이를 포함하고,It is provided in the catheter and includes a needle array having a plurality of needles for injecting the liquid into a target of a living body,
    상기 카테터의 헤드는 상기 카테터의 중심축선에 대해 경사지게 형성된 경사부를 포함하며,The head of the catheter includes an inclined portion formed to be inclined with respect to the central axis of the catheter,
    복수의 상기 니들은 상기 경사부로부터 돌출되도록 마련되는 것을 특징으로 하는 액체류 주입 장치.The plurality of needles are provided to protrude from the inclined portion.
  2. 제1항에 있어서,According to claim 1,
    복수의 상기 니들이 생체의 타겟에 삽입되도록 상기 카테터의 헤드를 변형시키는 변형 유닛을 더 포함하는 것을 특징으로 하는 액체류 주입 장치.The liquid injection device according to claim 1, further comprising a deforming unit configured to deform the head of the catheter so that the plurality of needles are inserted into the target of the living body.
  3. 제2항에 있어서,3. The method of claim 2,
    상기 변형 유닛은,The transformation unit is
    상기 카테터의 헤드에 결합되는 지지부재; 및a support member coupled to the head of the catheter; and
    상기 지지부재에 연결되어, 상기 카테터 헤드의 형상을 변형시키는 한 쌍의 조작 와이어를 포함하고,It is connected to the support member, including a pair of operating wires for deforming the shape of the catheter head,
    한 쌍의 상기 조작 와이어를 상반되게 인장 또는 이완시켜 상기 카테터의 헤드 형상을 변형시키며, 복수의 상기 니들이 생체 타겟에 삽입되는 방향 또는 깊이를 조절하는 것을 특징으로 하는 액체류 주입 장치.A liquid injection device, characterized in that by tensioning or relaxing a pair of the manipulation wires to change the shape of a head of the catheter, and controlling a direction or depth in which the plurality of needles are inserted into a biological target.
  4. 제3항에 있어서,4. The method of claim 3,
    상기 지지부재는 폐루프 형태를 가지며,The support member has a closed loop shape,
    한 쌍의 상기 조작 와이어의 헤드는, 각각 상기 지지부재의 양측에 결합되는 것을 특징으로 하는 액체류 주입 장치.The head of the pair of manipulation wires is coupled to both sides of the support member, respectively.
  5. 제2항에 있어서,3. The method of claim 2,
    상기 니들 어레이는, The needle array,
    상기 경사부에 결합되는 베이스; 및a base coupled to the inclined portion; and
    상기 베이스에 배치되는 복수의 니들을 포함하는 것을 특징으로 하는 액체류 주입 장치.A liquid injection device comprising a plurality of needles disposed on the base.
  6. 제1항에 있어서,According to claim 1,
    복수의 상기 니들은 상기 경사부로부터 일정 높이로 돌출되게 마련되는 것을 특징으로 하는 액체류 주입 장치.The plurality of needles are provided to protrude at a predetermined height from the inclined portion.
  7. 생검 채널에 입출 가능하게 마련되고, 액체류의 이동 경로를 제공하는 카테터; 및a catheter provided to be able to enter and exit the biopsy channel and provide a movement path for the liquid; and
    상기 카테터에 마련되어, 상기 액체류를 생체의 타겟에 주입하기 위한 복수의 니들을 구비하는 니들 어레이를 포함하고,It is provided in the catheter and includes a needle array having a plurality of needles for injecting the liquid into a target of a living body,
    복수의 상기 니들은 상기 카테터의 중심축선에 대해 가로방향으로 마련되는 것을 특징으로 하는 액체류 주입 장치.The plurality of needles are provided in a transverse direction with respect to the central axis of the catheter.
  8. 제7항에 있어서,8. The method of claim 7,
    복수의 상기 니들이 생체의 타겟에 삽입되도록 복수의 상기 니들이 마련된 상기 카테터의 일 영역을 변형시키는 변형 유닛을 더 포함하는 것을 특징으로 하는 액체류 주입 장치.The liquid injection device according to claim 1, further comprising a deforming unit configured to deform an area of the catheter in which the plurality of needles are provided so that the plurality of needles are inserted into the target of the living body.
  9. 제8항에 있어서,9. The method of claim 8,
    상기 변형 유닛은,The transformation unit is
    상호 관절 운동가능하게 상기 카테터의 길이방향을 따라 일렬 배치되는 복수의 단위관절부를 포함하며,It includes a plurality of unit joint parts arranged in a line along the longitudinal direction of the catheter to enable mutual joint movement,
    상기 단위관절부의 관절 운동에 따라 상기 카테터의 일 영역을 변형시키는 것을 특징으로 하는 액체류 주입 장치.Liquid injection device, characterized in that deforming a region of the catheter according to the joint movement of the unit joint portion.
  10. 제8항에 있어서,9. The method of claim 8,
    상기 변형 유닛은,The transformation unit is
    상기 카테터에 결합되는 한 쌍의 카테터 와이어를 포함하며,It includes a pair of catheter wires coupled to the catheter,
    한 쌍의 상기 카테터 와이어를 상반되게 인장 또는 이완시켜 상기 카테터의 일 영역을 변형시키는 것을 특징으로 하는 액체류 주입 장치A liquid flow injection device, characterized in that the pair of catheter wires are tensioned or relaxed in opposite directions to deform a region of the catheter.
  11. 제8항에 있어서,9. The method of claim 8,
    상기 변형 유닛은,The transformation unit is
    상기 카테터의 일 영역에 결합되는 지지부재; 및a support member coupled to an area of the catheter; and
    상기 지지부재에 연결되어, 상기 카테터의 일 영역의 형상을 변형시키는 한 쌍의 조작 와이어를 포함하고,It is connected to the support member, including a pair of operating wires for deforming the shape of a region of the catheter,
    한 쌍의 상기 조작 와이어를 상반되게 인장 또는 이완시켜 상기 카테터의 일 영역의 형상을 변형시키며, 복수의 상기 니들이 생체 타겟에 삽입되는 방향 또는 깊이를 조절하는 것을 특징으로 하는 액체류 주입 장치.A liquid injection device, characterized in that by tensioning or relaxing a pair of the manipulation wires to change the shape of one region of the catheter, and controlling the direction or depth in which the plurality of needles are inserted into the biological target.
  12. 제11항에 있어서,12. The method of claim 11,
    상기 지지부재는 폐루프 형태를 가지며,The support member has a closed loop shape,
    한 쌍의 상기 조작 와이어의 헤드는, 각각 상기 지지부재의 양측에 결합되는 것을 특징으로 하는 액체류 주입 장치.The head of the pair of manipulation wires is coupled to both sides of the support member, respectively.
  13. 제7항에 있어서,8. The method of claim 7,
    상기 니들 어레이는, The needle array,
    상기 카테터에 결합되는 베이스; 및a base coupled to the catheter; and
    상기 베이스에 배치되는 복수의 니들을 포함하는 것을 특징으로 하는 액체류 주입 장치.A liquid injection device comprising a plurality of needles disposed on the base.
  14. 제1항에 있어서,According to claim 1,
    상기 카테터는 탄성변형가능한 재질을 포함하는 것을 특징으로 하는 액체류 주입 장치.The catheter is a liquid injection device, characterized in that it comprises an elastically deformable material.
  15. 제7항에 있어서,8. The method of claim 7,
    상기 카테터는 탄성변형가능한 재질을 포함하는 것을 특징으로 하는 액체류 주입 장치.The catheter is a liquid injection device, characterized in that it comprises an elastically deformable material.
PCT/KR2022/001524 2021-03-29 2022-01-27 Liquid injection device WO2022211246A1 (en)

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KR102337886B1 (en) * 2021-03-29 2021-12-09 재단법인 아산사회복지재단 Liquid injection device

Citations (5)

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Publication number Priority date Publication date Assignee Title
US20070049863A1 (en) * 2003-01-14 2007-03-01 Jahns Scott E Devices and methods for interstitial injection of biologic agents into tissue
JP2010154895A (en) * 2008-12-26 2010-07-15 Olympus Corp Endoscopic apparatus
JP2016005543A (en) * 2014-05-26 2016-01-14 株式会社スズキプレシオン Injection needle device and injection appliance set
KR20210021189A (en) * 2019-08-14 2021-02-25 울산대학교 산학협력단 Injection apparatus using meedle array for liquid injection
KR102337886B1 (en) * 2021-03-29 2021-12-09 재단법인 아산사회복지재단 Liquid injection device

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US8585584B2 (en) 2004-10-11 2013-11-19 Nitesh Ratnakar Dual view endoscope

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Publication number Priority date Publication date Assignee Title
US20070049863A1 (en) * 2003-01-14 2007-03-01 Jahns Scott E Devices and methods for interstitial injection of biologic agents into tissue
JP2010154895A (en) * 2008-12-26 2010-07-15 Olympus Corp Endoscopic apparatus
JP2016005543A (en) * 2014-05-26 2016-01-14 株式会社スズキプレシオン Injection needle device and injection appliance set
KR20210021189A (en) * 2019-08-14 2021-02-25 울산대학교 산학협력단 Injection apparatus using meedle array for liquid injection
KR102337886B1 (en) * 2021-03-29 2021-12-09 재단법인 아산사회복지재단 Liquid injection device

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