WO2022104730A1 - 一种检测样本分析仪吸样的方法及装置 - Google Patents
一种检测样本分析仪吸样的方法及装置 Download PDFInfo
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- 238000000034 method Methods 0.000 title claims abstract description 25
- 238000012360 testing method Methods 0.000 title claims abstract description 19
- 238000010521 absorption reaction Methods 0.000 title abstract 2
- 238000005070 sampling Methods 0.000 claims abstract description 55
- 210000004369 blood Anatomy 0.000 claims abstract description 40
- 239000008280 blood Substances 0.000 claims abstract description 40
- 102000001554 Hemoglobins Human genes 0.000 claims abstract description 10
- 108010054147 Hemoglobins Proteins 0.000 claims abstract description 10
- 238000001514 detection method Methods 0.000 claims description 135
- 238000004140 cleaning Methods 0.000 claims description 22
- 238000002360 preparation method Methods 0.000 claims description 9
- 238000000926 separation method Methods 0.000 claims description 4
- 238000002347 injection Methods 0.000 claims description 2
- 239000007924 injection Substances 0.000 claims description 2
- 239000007788 liquid Substances 0.000 abstract description 8
- 239000003153 chemical reaction reagent Substances 0.000 abstract description 5
- 238000005259 measurement Methods 0.000 abstract description 2
- 210000004027 cell Anatomy 0.000 description 22
- 238000010586 diagram Methods 0.000 description 8
- 238000009534 blood test Methods 0.000 description 7
- 239000000243 solution Substances 0.000 description 4
- 210000000601 blood cell Anatomy 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 206010047700 Vomiting Diseases 0.000 description 1
- 238000004737 colorimetric analysis Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000012864 cross contamination Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
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- 230000011218 segmentation Effects 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
Definitions
- the present invention relates to the technical field of blood sample detection, and in particular, to a method and a device for detecting sample suction by a sample analyzer.
- the blood cell analyzer hence the name Siyi, is an instrument that draws blood samples for analysis, so to ensure the accuracy of the analysis results, the first step is to ensure that the instrument normally draws blood samples from the test tube containing the blood sample.
- the technical problem to be solved by the present invention is how to provide a method and a device for detecting sample suction by a sample analyzer, so as to reduce the cost of the instrument and improve the work efficiency.
- an embodiment of the present invention discloses a method for detecting sample suction by a sample analyzer, including: step a: moving the sampling needle into the sample pool to collect samples in the sample pool; The sampling needle is moved to the detection pool, and the blood of the head is spit out; step c: obtaining the detection value in the current detection pool; step d: judging whether the detection value belongs to the preset range value according to the obtained detection value; step e: if the detection value Within the preset range value, the sample analyzer executes the detection sequence.
- an embodiment of the present invention discloses a device for detecting sample suction by a sample analyzer, comprising: a sampling module for moving a sampling needle into a sample pool to collect samples in the sample pool; a sample injection module for moving the sampling needle to the detection pool, and spitting out the blood in the head; an acquisition module, used for acquiring the detection value in the current detection pool; a judgment module, used for judging whether the detection value belongs to a preset range value according to the acquired detection value; The detection module is used for the sample analyzer to execute the detection sequence when the detection value is within the preset range value.
- the present invention has the following beneficial effects: compared with the prior art, the embodiment of the present invention moves the sampling needle to the detection cell, spit out the blood in the head, and obtains the detection value of the liquid in the current detection cell through the detection device only in the analyzer ; Determine whether the detection value is within the preset range value; if the detection value is within the preset range value, the sample analyzer executes the detection sequence.
- the present invention does not increase the cost of the instrument; the components of the sample analyzer itself are used to detect whether the instrument absorbs the sample normally, make a judgment in time, adjust the calling test sequence, save unnecessary actions and reagent consumption, and improve work efficiency.
- FIG. 1 is a schematic structural diagram of the existing blood cell analyzer disclosed in this embodiment
- FIG. 2 is a flowchart of a method for detecting a sample aspirating by a sample analyzer disclosed in the present embodiment
- FIG. 3 is a schematic structural diagram of a device for detecting sample suction by a sample analyzer disclosed in this embodiment
- Fig. 4 is the structural representation of blood sample segmentation
- FIG. 5 is a schematic diagram of the method for detecting hemoglobin concentration disclosed in the present embodiment
- Fig. 6 is the detection and timing call flow chart disclosed in the present embodiment
- FIG. 7 is a schematic diagram of the voltage of the non-spitting blood test disclosed in the present embodiment.
- Fig. 8 is the voltage schematic diagram of the spitting 1ul head blood test disclosed in the present embodiment.
- Fig. 9 is the voltage schematic diagram of the spitting 2ul head blood test disclosed in the present embodiment.
- Fig. 10 is the voltage schematic diagram of the spit 3ul head blood test disclosed in the present embodiment.
- FIG. 11 is a schematic diagram of the voltage of the 4ul head blood test disclosed in this embodiment.
- the step e includes: the sampling needle moves to the corresponding detection channel according to the time sequence command, completes the specific blood separation action, the sample analyzer performs the detection of each item, and finally outputs the detection result.
- the sample analyzer calls the cleaning sequence, and cleans the inner and outer walls of the sampling needle and the detection cell through the cleaning sequence, so that the sampling needle and the detection cell are restored to the preparation state before detection.
- step a to step e are performed again.
- the sample analyzer calls the cleaning sequence, and the interface of the sample analyzer pops up a fault prompt box to terminate the detection sequence operation.
- the detection value is an AD value
- the preset range value is an AD preset range value
- the detection cell is a wbc cell
- the AD value is collected by a hemoglobin concentration detection device in the sample analyzer.
- the AD preset range value is 3100-3350.
- a cleaning module is also included for cleaning the inner and outer walls of the sampling needle and the detection cell when the detection value exceeds the preset range value, so as to restore the sampling needle and the detection cell to the preparation state before detection.
- a calling module which is used to sequentially call the sampling module, the sampling module, the acquisition module, the judgment module and the detection module to work after the sampling needle and the detection cell are restored to the preparation state before detection. If the detected value exceeds the preset range value again, the sample analyzer will call the cleaning module again to work, and the sample analyzer interface will pop up a fault prompt box to terminate the detection sequence operation.
- the terms “installed”, “connected” and “connected” should be understood in a broad sense, unless otherwise expressly specified and limited, for example, it may be a fixed connection or a detachable connection connection, or integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, or it can be the internal connection of two components, which can be a wireless connection or a wired connection connect.
- installed installed
- “connected” and “connected” should be understood in a broad sense, unless otherwise expressly specified and limited, for example, it may be a fixed connection or a detachable connection connection, or integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, or it can be the internal connection of two components, which can be a wireless connection or a wired connection connect.
- the embodiment of the present invention discloses a method for detecting sample suction by a sample analyzer, comprising:
- Step a move the sampling needle into the sample pool, and collect the samples in the sample pool;
- Step b move the sampling needle to the detection pool, and spit out the blood in the head;
- Step c obtain the detection value in the current detection pool
- Step d according to the acquired detection value, determine whether the detection value belongs to the preset range value;
- Step e If the detection value is within the preset range value, the sample analyzer executes the detection sequence.
- the sampling needle is moved to the detection tank, the blood in the head is spit out, and the detection value of the liquid in the current detection tank is obtained through the detection device only in the analyzer; Whether the detection value is within the preset range value; if the detection value is within the preset range value, the sample analyzer executes the detection sequence.
- the present invention will not increase the cost of the instrument; the components of the sample analyzer itself are used to detect whether the instrument normally absorbs the sample, make a judgment in time, adjust the calling test sequence, save unnecessary actions and reagent consumption, and improve work efficiency.
- FIG. 2 it includes: S101.
- the sampling needle enters the wbc pool under the movement of the sampling assembly in the analyzer, and spit out the blood in the head;
- S102. Issue a collection instruction to the hemoglobin concentration detection device, read The current AD value of the liquid voltage signal in the wbc cell;
- S103. Determine whether the AD value is within the preset range;
- S104. If the AD value is within the preset range, the sample analyzer executes the detection sequence.
- the invention does not increase the cost of the instrument; the hemoglobin concentration detection device itself belongs to the device only carried by the existing analyzer. By detecting whether the instrument normally absorbs the sample, it can make a judgment in time, adjust the calling test sequence, and save unnecessary actions and reagents consumption and improve work efficiency.
- step e includes: moving the sampling needle to the corresponding detection channel according to the time sequence command to complete the specific blood separation action, the sample analyzer performs the detection of each item, and finally outputs the detection result.
- the sample analyzer calls the cleaning sequence, and cleans the inner and outer walls of the sampling needle and the detection cell through the cleaning sequence, so that the sampling needle and the detection cell are restored to the preparation state before detection.
- step a to step e are performed again.
- the sample analyzer calls the cleaning sequence, and the interface of the sample analyzer pops up a fault prompt box to terminate the detection sequence operation.
- the detection value is an AD value
- the preset range value is an AD preset range value
- the detection cell is a wbc cell
- the AD value is collected by a hemoglobin concentration detection device in the sample analyzer.
- the AD preset range value is 3100 ⁇ 3350.
- an embodiment of the present invention discloses a device for detecting sample suction by a sample analyzer, including: a sampling module 101 for moving a sampling needle into a sample pool to collect samples in the sample pool; a sampling module 102 , used to move the sampling needle to the detection pool and spit out the blood in the head; the acquisition module 103 is used to acquire the detection value in the current detection pool; the judgment module 104 is used to determine whether the detection value belongs to the preset range according to the acquired detection value The detection module 105 is used for, when the detection value is within the preset range value, the sample analyzer executes the detection sequence.
- a cleaning module 106 is also included, for cleaning the inner and outer walls of the sampling needle and the detection cell when the detection value exceeds the preset range value, so as to restore the sampling needle and the detection cell to the preparation state before detection.
- a calling module 107 which is used to sequentially call the sampling module, the sampling module, the acquisition module, the judgment module and the detection module to work after the sampling needle and the detection cell are restored to the preparation state before detection. If the second detection value exceeds the preset range value again, the sample analyzer will call the cleaning module again to work, and the interface of the sample analyzer will pop up a fault prompt box to terminate the detection sequence operation.
- a is the head blood
- the syringe eliminates the stroke difference from suction to discharge by throwing the head blood; then the sample blood volume required for wbc counting; then throw away the blood sample b to avoid channel crossing Contamination, then the blood volume required for crp counting; then throw away the blood sample of part c to avoid cross-contamination of the channel; then the blood sample required for diff classification; and finally the tail blood d is cleaned and removed together with the inside of the cleaning sampling needle.
- the blood thrown away by the normal instrument such as a, b, c, and d in Figure 4, is recovered inside the swab, collected and discharged under the negative pressure of the waste liquid module connected to the swab assembly.
- the method for detecting whether the instrument is normally aspirating the sample is to divide the blood from the head into the wbc pool instead of throwing it in the swab, and then test the background voltage at this time through the device for detecting the concentration of hemoglobin in the instrument itself. Whether it is within the preset range to judge whether the suction is normal.
- the hemoglobin concentration is measured by colorimetry.
- the LED light tube emits light with a center wavelength of 525 nm to illuminate the solution in the detection cell, and the other end receives the projected light through the photocell, and then the light signal is converted into a voltage.
- the signal is compared with the background voltage signal tested at the beginning of the detection cell (the detection cell only has diluent at the beginning, and the transmitted light signal is the strongest), and the concentration of the sample hemoglobin is calculated.
- FIG. 6 is a flow chart of detection and timing invocation disclosed in this embodiment.
- FIG. 7 is the voltage of the test without spitting blood in the head
- Figure 8 is the voltage in the test of vomiting 1ul blood in the head
- Figure 9 is the voltage in the test with blood in the head of 2ul
- 10 is the voltage of spit 3ul head blood test
- Figure 11 is the voltage of 4ul head blood test.
- the embodiments of the present application only provide a way, and a more accurate AD value can be obtained by using a higher-precision measurement and detection device.
- the sampling needle enters the wbc pool under the movement of the sampling assembly in the analyzer, and spit out the blood in the head; Take the AD value of the liquid voltage signal in the current wbc cell; determine whether the AD value is within the preset range; if the AD value is within the preset range, the sample analyzer executes the detection sequence.
- the present invention does not increase the cost of the instrument; by detecting whether the instrument normally draws samples, judgment is made in time, the calling test sequence is adjusted, unnecessary actions and reagent consumption are saved, and work efficiency is improved.
- the head blood can be spit into the crp counting pool, and the AD value in the crp pool can be detected by the crp detection device in the sample analyzer to determine whether the AD value is within the preset range; Within the set range, the sample analyzer executes the detection sequence, that is, through the sequence command, the samples in the sampling needle are sequentially injected into the crp pool, the wbc pool and the diff classification pool for detection.
- the present application has industrial applicability.
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Abstract
一种检测样本分析仪吸样的方法及装置,涉及血样检测技术领域,该方法包括:通过采样针在运动组件的移动下进入wbc池,吐出头段的血,仪器吸取样本;对血红蛋白浓度检测装置下发采集指令,读取当前wbc池内的液体电压信号AD值;判断AD值是否属于预设范围内;若AD值处于预设范围内,则检测仪器执行检测时序,并输出检测结果。该方法不会增加仪器成本;可以通过根据检测到仪器是否正常吸取样本,及时做出判断,调整调用的测试时序,节约不必要的动作和试剂消耗,提高工作效率。
Description
本发明涉及血样检测技术领域,尤其涉及一种检测样本分析仪吸样的方法及装置。
近年来,我国的检验医学事业有着飞速的发展,各种各样的血液分析仪在国内迅速普及,血细胞分析仪开始逐步取代镜检成为进行血常规分析的重要手段,不但提高了检验结果的效率,也给临床提供更多可靠地试验指标,对疾病的诊断和鉴别起到重要作用。血液细胞分析仪,故名思议,是吸取血样进行分析的仪器,所以要保证分析结果是否准确,第一步就是保证仪器正常从盛液血样的试管内正常吸取血样。
目前只有小部分的血液细胞分析仪提供有检测吸样有无功能,并且大部分采用的是光电传感器,通过检测经过传感器的光电信号的变化来判断是否吸取样本或者吸取样本正常。CN
107687963 A专利采用的就是这种方式,如图1所示,采样注射器下来,吸取足够多的样本,使样本至少超过透光管路上设置的光电传感器组件的位置,然后通过根据传感器反馈的检测信号来判断吸样是否正常。
但是这种方法有它的局限性,如图1所示,吸样时,采样注射器下拉,在负压作用下,样本被吸入采样针,然后经过光电传感器的透明管路。但是由于采样针采用的是不锈钢材质,所以它不透光,如果要使光电传感器起作用,样本液面一定要拉至透明管路,超过传感器位置。目前国内的穿刺采样针一般容积是30ul,如果要拉至光电传感器位置至少需要40ul,但是一般的检测模式血常规五分类加CRP或和SAA的血样都不需要超过30ul,所以这种方式除非用在耗血量比较大的综合性仪器上,否则很难触发光电传感器型号。
因此,如何提供一种检测样本分析仪吸样的方法和时序调度方法,以降低仪器成本及提高工作效率成为亟待解决的技术问题。
本发明要解决的技术问题在于如何提供一种检测样本分析仪吸样的方法及装置,以降低仪器成本及提高工作效率。
为此,根据第一方面,本发明实施例公开了一种检测样本分析仪吸样的方法,包括:步骤a:将采样针移动到样本池中,采集样本池内的样本;步骤b:将所述采样针移动到检测池,吐出头段的血;步骤c:获取当前检测池内的检测值;步骤d:根据获取的检测值判断检测值是否属于预设范围值内;步骤e:若检测值处于预设范围值内,则样本分析仪执行检测时序。
根据第二方面,本发明实施例公开了一种检测样本分析仪吸样的装置,包括:采样模块,用于将采样针移动到样本池中,采集样本池内的样本;进样模块,用于将所述采样针移动到检测池,吐出头段的血;获取模块,用于获取当前检测池内的检测值;判断模块,用于根据获取的检测值判断检测值是否属于预设范围值内;检测模块,用于当检测值处于预设范围值内,则样本分析仪执行检测时序。
本发明具有以下有益效果:与现有技术相比,本发明实施例通过将采样针移动到检测池,吐出头段的血,通过分析仪内只带的检测装置获取当前检测池内的液体检测值;判断检测值是否属于预设范围值内;若检测值处于预设范围值内,则样本分析仪执行检测时序。本发明不会增加仪器成本;通过样本分析仪本身自带的部件检测仪器是否正常吸取样本,及时做出判断,调整调用的测试时序,节约不必要的动作和试剂消耗,提高工作效率。
为了更清楚地说明本发明具体实施方式或现有技术中的技术方案,下面将对具体实施方式或现有技术描述中所需要使用的附图作简单地介绍,显而易见地,下面描述中的附图是本发明的一些实施方式,对于本领域普通技术人员来讲,在不付出创造性劳动的前提下,还可以根据这些附图获得其他的附图。
图1是本实施例公开的现有血液细胞分析仪的结构示意图;
图2是本实施例公开的一种检测样本分析仪吸样的方法的流程图;
图3是本实施例公开的一种检测样本分析仪吸样的装置的结构示意图;
图4是血样分段的结构示意图;
图5是本实施例公开的血红蛋白浓度检测方法的示意图;
图6是本实施例公开的检测和时序调用流程图;
图7是本实施例公开的不吐头段血测试的电压示意图;
图8是本实施例公开的吐1ul头段血测试的电压示意图;
图9是本实施例公开的吐2ul头段血测试的电压示意图;
图10是本实施例公开的吐3ul头段血测试的电压示意图;
图11是本实施例公开的吐4ul头段血测试的电压示意图。
可选地,所述步骤e包括:采样针按时序命令运动到对应的检测通道,完成具体的分血动作,样本分析仪进行每个项目的检测,最后输出检测结果。
可选地,若检测值超出预设范围值内,则样本分析仪调用清洗时序,通过清洗时序,清洗采样针内外壁和检测池,使采样针和检测池恢复至检测前的准备状态。
可选地,当完成所述清洗时序后,再次进行步骤a到步骤e的动作。
可选地,若第二次的检测值再次超出预设范围值内,则样本分析仪调用清洗时序,样本分析仪界面跳出故障提示框,终止检测时序操作。
可选地,所述检测值为AD值,所述预设范围值为AD预设范围值,所述检测池为wbc池,所述AD值通过样本分析仪中的血红蛋白浓度检测装置采集。
可选地,所述AD预设范围值为3100~3350。
可选地,还包括清洗模块,用于当检测值超出预设范围值内时,对采样针内外壁和检测池进行清洗,使采样针和检测池恢复至检测前的准备状态。
可选地,还包括调用模块,用于当采样针和检测池恢复至检测前的准备状态后,依次调用采样模块、进样模块、获取模块、判断模块和检测模块进行工作,若第二次的检测值再次超出预设范围值内,则样本分析仪再次调用清洗模块工作,并且样本分析仪界面跳出故障提示框,终止检测时序操作。
为了使本发明的目的、技术方案及优点更加清楚明白,以下结合附图及实施例,对本发明进行进一步详细说明。应当理解,此处所描述的具体实施例仅仅用以解释本发明,并不用于限定本发明。
在本发明的描述中,需要说明的是,术语“中心”、“上”、“下”、“左”、“右”、“竖直”、“水平”、“内”、“外”等指示的方位或位置关系为基于附图所示的方位或位置关系,仅是为了便于描述本发明和简化描述,而不是指示或暗示所指的装置或元件必须具有特定的方位、以特定的方位构造和操作,因此不能理解为对本发明的限制。此外,术语“第一”、“第二”、“第三”仅用于描述目的,而不能理解为指示或暗示相对重要性。
在本发明的描述中,需要说明的是,除非另有明确的规定和限定,术语“安装”、“相连”、“连接”应做广义理解,例如,可以是固定连接,也可以是可拆卸连接,或一体地连接;可以是机械连接,也可以是电连接;可以是直接相连,也可以通过中间媒介间接相连,还可以是两个元件内部的连通,可以是无线连接,也可以是有线连接。对于本领域的普通技术人员而言,可以具体情况理解上述术语在本发明中的具体含义。
此外,下面所描述的本发明不同实施方式中所涉及的技术特征只要彼此之间未构成冲突就可以相互结合。
本发明实施例公开了一种检测样本分析仪吸样的方法,包括:
步骤a:将采样针移动到样本池中,采集样本池内的样本;
步骤b:将所述采样针移动到检测池,吐出头段的血;
步骤c:获取当前检测池内的检测值;
步骤d:根据获取的检测值判断检测值是否属于预设范围值内;
步骤e:若检测值处于预设范围值内,则样本分析仪执行检测时序。
需要说明的是,与现有技术相比,本发明实施例通过将采样针移动到检测池,吐出头段的血,通过分析仪内只带的检测装置获取当前检测池内的液体检测值;判断检测值是否属于预设范围值内;若检测值处于预设范围值内,则样本分析仪执行检测时序。本发明不会增加仪器成本;通过样本分析仪本身自带的部件检测仪器是否正常吸取样本,及时做出判断,调整调用的测试时序,节约不必要的动作和试剂消耗,提高工作效率。
具体的,如图2所示,包括:S101.采样针在分析仪中的进样组件的移动下进入wbc池,吐出头段的血;S102.对血红蛋白浓度检测装置下发采集指令,读取当前wbc池内的液体电压信号AD值;S103.判断AD值是否属于预设范围内;S104.若AD值处于预设范围内,则样本分析仪执行检测时序。本发明不会增加仪器成本;血红蛋白浓度检测装置本身属于现有分析仪只带的装置,通过检测到仪器是否正常吸取样本,及时做出判断,调整调用的测试时序,节约不必要的动作和试剂消耗,提高工作效率。
可选地,步骤e包括:采样针按时序命令运动到对应的检测通道,完成具体的分血动作,样本分析仪进行每个项目的检测,最后输出检测结果。
可选地,若检测值超出预设范围值内,则样本分析仪调用清洗时序,通过清洗时序,清洗采样针内外壁和检测池,使采样针和检测池恢复至检测前的准备状态。
可选地,当完成清洗时序后,再次进行步骤a到步骤e的动作。
可选地,若第二次的检测值再次超出预设范围值内,则样本分析仪调用清洗时序,样本分析仪界面跳出故障提示框,终止检测时序操作。
可选地,检测值为AD值,预设范围值为AD预设范围值,检测池为wbc池,AD值通过样本分析仪中的血红蛋白浓度检测装置采集。
可选地,AD预设范围值为3100~3350。
如图3所示,本发明实施例公开了一种检测样本分析仪吸样的装置,包括:采样模块101,用于将采样针移动到样本池中,采集样本池内的样本;进样模块102,用于将采样针移动到检测池,吐出头段的血;获取模块103,用于获取当前检测池内的检测值;判断模块104,用于根据获取的检测值判断检测值是否属于预设范围值内;检测模块105,用于当检测值处于预设范围值内,则样本分析仪执行检测时序。
可选地,还包括清洗模块106,用于当检测值超出预设范围值内时,对采样针内外壁和检测池进行清洗,使采样针和检测池恢复至检测前的准备状态。
可选地,还包括调用模块107,用于当采样针和检测池恢复至检测前的准备状态后,依次调用采样模块、进样模块、获取模块、判断模块和检测模块进行工作,若第二次的检测值再次超出预设范围值内,则样本分析仪再次调用清洗模块工作,并且样本分析仪界面跳出故障提示框,终止检测时序操作。
如图4所示,a是头段血,注射器通过扔头段血消除注射器从吸变成排的行程差;然后是wbc计数需要的样本血量;接着是扔掉b部分血样,避免通道交叉污染,然后是crp计数需要的血量;接着是扔掉c部分血样,避免通道交叉污染;然后是diff分类需要的血样;最后的尾端血d随清洗采样针内部一起清洗排除。
正常仪器扔掉的血,如图4中的a,b,c,d是通过拭子内部回收,在与拭子组件相连的废液模块的负压作用收集和排出。
本申请提供的检测仪器是否正常吸样的办法是通过把头段血分在wbc池,而不是扔在拭子内部,然后通过仪器本身带有的检测血红蛋白浓度的装置测试此时的本底电压判断是否在预设定的范围内来判断吸样是否正常。
下面以具体的实施方式对本申请进行详细说明。
如图5所示,比色法测试血红蛋白浓度,在检测池的一端让LED光管发出中心波长525nm的光照射检测池内的溶液,在另外一端通过光电管接收投射光,然后光信号转化成电压信号,通过与检测池最开始(最开始检测池只有稀释液,透射光信号最强)测试的本底电压信号进行对比,计算得到样本血红蛋白的浓度。
图6是本实施例公开的检测和时序调用流程图。
AD值的范围是通过多次实验得出的,图7是不吐头段血测试的电压;图8是吐1ul头段血测试的电压;图9是吐2ul头段血测试的电压;图10是吐3ul头段血测试的电压;图11是吐4ul头段血测试的电压。
结合测试数据,同时考虑到采集电压是在250ms内瞬时完成,并且信号采集中仪器电机注射器是一直在工作,所以存在个别仪器的振动导致液面波动从而电压AD值的波动,同时参考每次分血量会有略微的偏差,于是设定:AD值在3100~3350内,代表分血正常,即仪器吸样正常。当然本申请实施例只是提供一种方式,采用更高精度测检测装置可以获取更精准的AD值。
工作原理:与现有技术相比,本发明实施例中,采样针在分析仪中的进样组件的移动下进入wbc池,吐出头段的血;对血红蛋白浓度检测装置下发采集指令,读取当前wbc池内的液体电压信号AD值;判断AD值是否属于预设范围内;若AD值处于预设范围内,则样本分析仪执行检测时序。本发明不会增加仪器成本;通过检测到仪器是否正常吸取样本,及时做出判断,调整调用的测试时序,节约不必要的动作和试剂消耗,提高工作效率。
另一个实施例中,可以将头段血吐入crp计数池内,通过样本分析仪中的crp检测装置检测crp池内的AD值,判断该AD值是否属于预设范围内;若该AD值处于预设范围内,则样本分析仪执行检测时序,即通过时序命令,将采样针内的样本依次注入crp池、wbc池和diff分类池内进行检测。
显然,上述实施例仅仅是为清楚地说明所作的举例,而并非对实施方式的限定。对于所属领域的普通技术人员来说,在上述说明的基础上还可以做出其它不同形式的变化或变动。这里无需也无法对所有的实施方式予以穷举。而由此所引伸出的显而易见的变化或变动仍处于本发明创造的保护范围之中。
本申请具有工业实用性。
Claims (10)
- 一种检测样本分析仪吸样的方法,其特征在于,包括:步骤a:将采样针移动到样本池中,采集样本池内的样本;步骤b:将所述采样针移动到检测池,吐出头段的血;步骤c:获取当前检测池内的检测值;步骤d:根据获取的检测值判断检测值是否属于预设范围值内;步骤e:若检测值处于预设范围值内,则样本分析仪执行检测时序。
- 根据权利要求1所述的检测样本分析仪吸样的方法,其特征在于,所述步骤e包括:采样针按时序命令运动到对应的检测通道,完成具体的分血动作,样本分析仪进行每个项目的检测,最后输出检测结果。
- 根据权利要求1所述的检测样本分析仪吸样的方法,其特征在于,若检测值超出预设范围值内,则样本分析仪调用清洗时序,通过清洗时序,清洗采样针内外壁和检测池,使采样针和检测池恢复至检测前的准备状态。
- 根据权利要求3所述的检测样本分析仪吸样的方法,其特征在于,当完成所述清洗时序后,再次进行步骤a到步骤e的动作。
- 根据权利要求4所述的检测样本分析仪吸样的方法,其特征在于,若第二次的检测值再次超出预设范围值内,则样本分析仪调用清洗时序,样本分析仪界面跳出故障提示框,终止检测时序操作。
- 根据权利要求1-5任意一项所述的检测样本分析仪吸样的方法,其特征在于,所述检测值为AD值,所述预设范围值为AD预设范围值,所述检测池为wbc池,所述AD值通过样本分析仪中的血红蛋白浓度检测装置采集。
- 根据权利要求6所述的检测样本分析仪吸样的方法,其特征在于,所述AD预设范围值为3100~3350。
- 一种检测样本分析仪吸样的装置,其特征在于,包括采样模块,用于将采样针移动到样本池中,采集样本池内的样本;进样模块,用于将所述采样针移动到检测池,吐出头段的血;获取模块,用于获取当前检测池内的检测值;判断模块,用于根据获取的检测值判断检测值是否属于预设范围值内;检测模块,用于当检测值处于预设范围值内,样本分析仪执行检测时序。
- 根据权利要求8所述的检测样本分析仪吸样的装置,其特征在于,还包括清洗模块,用于当检测值超出预设范围值内时,对采样针内外壁和检测池进行清洗,使采样针和检测池恢复至检测前的准备状态。
- 根据权利要求9所述的检测样本分析仪吸样的装置,其特征在于,还包括调用模块,用于当采样针和检测池恢复至检测前的准备状态后,依次调用采样模块、进样模块、获取模块、判断模块和检测模块进行工作,若第二次的检测值再次超出预设范围值内,则样本分析仪再次调用清洗模块工作,并且样本分析仪界面跳出故障提示框,终止检测时序操作。
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