WO2021237895A1 - Information acquisition device - Google Patents

Information acquisition device Download PDF

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Publication number
WO2021237895A1
WO2021237895A1 PCT/CN2020/101779 CN2020101779W WO2021237895A1 WO 2021237895 A1 WO2021237895 A1 WO 2021237895A1 CN 2020101779 W CN2020101779 W CN 2020101779W WO 2021237895 A1 WO2021237895 A1 WO 2021237895A1
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Prior art keywords
optical fiber
self
sample
signal
ultrasonic probe
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PCT/CN2020/101779
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French (fr)
Chinese (zh)
Inventor
纪轩荣
陈燕
张东来
曾吕明
袁懋诞
邓丽军
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广东工业大学
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Publication of WO2021237895A1 publication Critical patent/WO2021237895A1/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/08—Detecting organic movements or changes, e.g. tumours, cysts, swellings
    • A61B8/0891—Detecting organic movements or changes, e.g. tumours, cysts, swellings for diagnosis of blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0093—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy
    • A61B5/0095—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy by applying light and detecting acoustic waves, i.e. photoacoustic measurements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/44—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
    • A61B8/4416—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device related to combined acquisition of different diagnostic modalities, e.g. combination of ultrasound and X-ray acquisitions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/44—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
    • A61B8/4444—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device related to the probe
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/44—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
    • A61B8/4444—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device related to the probe
    • A61B8/4455—Features of the external shape of the probe, e.g. ergonomic aspects
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/44—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
    • A61B8/4483—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device characterised by features of the ultrasound transducer
    • A61B8/4488—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device characterised by features of the ultrasound transducer the transducer being a phased array

Definitions

  • the present invention relates to the technical field of information collection, in particular to an information collection device.
  • Intravascular ultrasound imaging The use of miniature ultrasound transducers to detect the size of the lumen and the structure of the wall through the imaging of the inside of the blood vessel, which can display the cross-sectional anatomy of the blood vessel in real time, and plays an irreplaceable role in the detection of various vascular diseases.
  • the present invention provides an information acquisition device, which can collect multiple signals in blood vessels, and use multiple signal modes to image, which can greatly improve the accuracy of detection and avoid the possibility of images obtained by simply collecting ultrasound signals for blood vessel detection. There are artifacts that cannot completely accurately reflect the internal structure of blood vessels.
  • the present invention provides an information acquisition device, including: a transparent ultrasonic probe, a laser source, a miniature CCD image sensor, a first discrete end optical fiber, a second discrete end optical fiber, and a self-focusing coupling optical fiber;
  • the first end of the first discrete-end optical fiber is connected to a laser source, the second end is connected to the first end of the self-focusing coupling optical fiber through a fiber coupler, and the second end of the self-focusing coupling optical fiber is connected to the transparent Ultrasound probe connection;
  • the first end of the second discrete-end optical fiber is connected to the miniature CCD image sensor, and the second end is connected to the first end of the self-focusing coupling optical fiber through an optical fiber coupler;
  • the laser source is used to emit laser light, and the laser light is irradiated on the sample to be tested through the first discrete end optical fiber and the self-focusing coupling optical fiber and through the transparent ultrasonic probe to generate a photoacoustic signal;
  • the transparent ultrasonic probe is provided with a piezoelectric element containing rare earth, and the piezoelectric element containing rare earth is used to be excited by the laser to generate fluorescence, and the fluorescence is irradiated on the sample to be tested to generate an optical signal;
  • the transparent ultrasonic probe is used to transmit an ultrasonic signal and receive the echo of the ultrasonic signal and the photoacoustic signal.
  • the piezoelectric element is a piezoelectric material containing rare earth.
  • the rare earth element in the piezoelectric element containing rare earth is selected from Eu, Er, Pr, Sm, La, Tb, Gd or Lu.
  • the piezoelectric material in the piezoelectric element containing rare earths is selected from piezoelectric single crystals, piezoelectric ceramics, or composite materials formed by piezoelectric ceramics and polymers.
  • the sample to be tested is in the shape of a cavity.
  • the sample to be tested includes a blood vessel or a pipe.
  • it further includes: a first imaging module and a second imaging module;
  • the first imaging module is connected with the micro CCD image sensor, and the second imaging module is connected with the transparent ultrasound probe.
  • the unit arrangement mode of the piezoelectric element containing rare earth is a single array element arrangement, a linear array arrangement or a surface array arrangement.
  • the shape of the transparent ultrasonic probe is concave or convex.
  • the laser source is a pulsed laser.
  • the present invention provides an information acquisition device, in which laser light emitted by a laser source is transmitted to a self-focusing coupling optical fiber through a first discrete end optical fiber, and the self-focusing laser beam output by the self-focusing coupling optical fiber is focused on the object to be measured through a transparent ultrasonic probe On the surface of the sample, the generated photoacoustic signal is received by the transparent ultrasonic probe.
  • the piezoelectric element is excited by the laser to generate fluorescence, and the fluorescence is irradiated to the sample to be tested to generate an optical signal.
  • the optical signal is output to the micro CCD image sensor through the self-focusing coupling optical fiber and the second discrete end optical fiber to be converted into an electrical signal.
  • the transparent probe can also transmit and receive ultrasonic signals by itself.
  • the device can collect the optical signal, photoacoustic signal and ultrasonic signal of the sample to be tested. After the subsequent analysis and processing of the three signals, the internal conditions of the sample to be tested can be observed.
  • the imaging results of the three signals are compared with each other, and the advantages and disadvantages are complementary. It can greatly improve the accuracy of the detection of the sample to be tested.
  • FIG. 1 is a schematic structural diagram of an information collection device provided by an embodiment of the present invention.
  • the embodiment of the present invention provides an information acquisition device, which is used to solve the problem that the current blood vessel detection simply collects ultrasound signals and uses ultrasound imaging to obtain images that may have artifacts and cannot completely accurately reflect the internal structure of the blood vessel.
  • An embodiment of an information acquisition device provided by the present invention includes: a transparent ultrasonic probe 1, a laser source 5, a miniature CCD image sensor 4, a first discrete end optical fiber 2, a second discrete end optical fiber 8 and a self-focusing coupling optical fiber 3 ;
  • the first end of the first discrete-end optical fiber 2 is connected to the laser source 5, the second end of the first discrete-end optical fiber 2 and the first end of the self-focusing coupling fiber 3 are connected through the fiber coupler 7, and the first end of the self-focusing coupling fiber 3 is The two ends are connected with the transparent ultrasonic probe 1;
  • the first end of the second discrete-end optical fiber 8 is connected to the miniature CCD image sensor 4, and the second end is connected to the first end of the self-focusing coupling optical fiber 3 through an optical fiber coupler 7;
  • the laser source 5 is used for emission and excitation.
  • the laser is irradiated to the sample 6 to be tested through the first discrete end optical fiber 2 and the self-focusing coupling optical fiber 3, and is irradiated on the sample 6 to generate a photoacoustic signal;
  • the transparent ultrasonic probe 1 is provided with a rare earth-containing Piezoelectric elements, piezoelectric elements containing rare earths are used to generate fluorescence after being excited by laser, and the fluorescence is irradiated on the sample 6 to be tested to generate light signals;
  • the transparent ultrasonic probe 1 is used to transmit ultrasonic signals and receive echo and photoacoustic signals of ultrasonic signals;
  • the laser light emitted by the laser source 5 is transmitted to the self-focusing coupling fiber 3 through the first discrete end optical fiber 2, and the self-focusing laser beam output by the self-focusing coupling fiber 3 is focused on the sample 6 to be tested through the transparent ultrasonic probe 1 On the surface, the generated photoacoustic signal is received by the transparent ultrasonic probe 1, and then transmitted to the outside for analysis and processing for imaging.
  • the piezoelectric element containing rare earth in the transparent ultrasonic probe 1 will generate fluorescence after being excited by the laser, and the fluorescence will illuminate the sample 6 to be tested.
  • the light signal reflected on the sample 6 to be tested passes through the self-focusing coupling fiber 3 and the second discrete end fiber 9 It is output to the micro CCD image sensor 4 and converted into an electric signal.
  • the transparent probe can also transmit and receive ultrasonic signals by itself, and then transmit them to the outside for analysis and processing for imaging.
  • the information collection device can collect the optical signal, photoacoustic signal and ultrasonic signal of the sample 6 to be tested. After the three signals are analyzed and processed and imaged, the internal condition of the sample 6 to be tested can be observed, which greatly improves the sample to be tested. 6 Accuracy of detection.
  • the rare earth element in the piezoelectric element containing rare earth is selected from Eu, Er, Pr, Sm, La, Tb, Gd or Lu.
  • the piezoelectric material in the piezoelectric element containing rare earths is selected from piezoelectric single crystals, piezoelectric ceramics, or composite materials formed by piezoelectric ceramics and polymers.
  • the sample 6 to be tested is in the shape of a cavity.
  • the sample 6 to be tested includes a blood vessel or a pipe, and in this embodiment, it is preferably a blood vessel.
  • the present invention also provides another embodiment of an information acquisition device.
  • the unit arrangement mode of the piezoelectric element containing rare earth elements is a single array element arrangement, a linear array arrangement or a surface array arrangement.
  • the information acquisition device further includes: a first imaging module and a second imaging module;
  • the first imaging module is connected with the miniature CCD image sensor 4, and the second imaging module is connected with the transparent ultrasound probe 1.
  • the first imaging module can realize fluorescence imaging. Specifically, the optical signal is converted into an electrical signal by the CCD image sensor 4, the electrical signal is amplified, and then converted into a digital signal, and the digital signal forms an image after data processing. Complete fluorescence imaging.
  • the second imaging module can realize photoacoustic imaging and ultrasound imaging. Specifically, ultrasound signals and photoacoustic signals are converted into electrical signals. The electrical signals are amplified and then converted into digital signals. Acoustic imaging.
  • the imaging principles of the first imaging module and the second imaging module are based on the prior art, and will not be described in detail in the embodiment of the present invention.
  • the information acquisition device utilizes the high contrast of photoacoustic imaging and the high penetration depth of ultrasonic imaging to achieve imaging effects of high accuracy, good resolution, and high restoration, and combines the photoacoustic imaging results with the ultrasonic imaging results Performing analysis and comparison together greatly improves the accuracy of detection.
  • the device integrates photoacoustic imaging, ultrasound imaging and fluorescence imaging, and compares each other, complements the advantages and disadvantages, has good imaging effects, and greatly improves the detection accuracy of the inside of blood vessels.
  • the shape of the transparent ultrasonic probe 1 is concave or convex.
  • the transparent ultrasonic probe 1 may have any shape, and the embodiment of the present invention does not specifically limit the shape of the transparent ultrasonic probe 1.
  • the laser source 5 is a pulsed laser.

Abstract

An information acquisition device. Laser emitted by a laser source (5) is transmitted to a self-focusing coupling optical fiber (3) by means of a first discrete end optical fiber (2), a self-focusing laser beam output by the self-focusing coupling optical fiber (3) penetrates a transparent ultrasonic probe (1) and is focused on the surface of a sample (6) to be tested, so as to generate a photoacoustic signal, and the transparent ultrasonic probe (1) receives the photoacoustic signal; a rare earth-containing piezoelectric element is excited by the laser to generate fluorescence, the fluorescence irradiates said sample (6) to generate an optical signal, and the optical signal is transmitted to a miniature CCD image sensor (4) by means of the transparent ultrasonic probe (1) via the self-focusing coupling optical fiber (3) and a second discrete end optical fiber (8); and the transparent ultrasonic probe (1) itself can also transmit and receive an ultrasonic signal. Said device can acquire an optical signal, a photoacoustic signal and an ultrasonic signal of a sample to be tested, and internal conditions of said sample can be observed after the three signals are analyzed, processed and imaged; and imaging results of the three signals are compared with one another, and the advantages and disadvantages are complementary, greatly improving the accuracy of test.

Description

一种信息采集装置Information collection device
本申请要求于2020年5月27日提交中国专利局、申请号为202010460838.4、发明名称为“一种信息采集装置”的中国专利申请的优先权，其全部内容通过引用结合在本申请中。This application claims the priority of a Chinese patent application filed with the Chinese Patent Office on May 27, 2020, with an application number of 202010460838.4 and an invention title of "an information collection device", the entire content of which is incorporated into this application by reference.
技术领域Technical field
本发明涉及信息采集技术领域，尤其涉及一种信息采集装置。The present invention relates to the technical field of information collection, in particular to an information collection device.
背景技术Background technique
随着经济水平的快速发展，人民生活水平的急速提高，血管类疾病的威胁也日益凸显，其发病率逐年上升。传统的血管检测方法有磁共振血管造影，CT血管造影等，这些方法虽然可以很好的显示血管的外部形态与内部轮廓，但无法显示血管壁与血管腔内详细的结构，而血管内超声成像利用微型超声换能器，通过血管内部成像来检测管腔大小与管壁结构，能够实时显示血管横断面解剖结构，在各种血管类疾病的检测中发挥着不可替代的作用。With the rapid development of the economy and the rapid improvement of people's living standards, the threat of vascular diseases has become increasingly prominent, and the incidence of them has been increasing year by year. Traditional blood vessel detection methods include magnetic resonance angiography, CT angiography, etc. Although these methods can display the external shape and internal contours of blood vessels, they cannot display the detailed structure of the blood vessel wall and vascular cavity. Intravascular ultrasound imaging The use of miniature ultrasound transducers to detect the size of the lumen and the structure of the wall through the imaging of the inside of the blood vessel, which can display the cross-sectional anatomy of the blood vessel in real time, and plays an irreplaceable role in the detection of various vascular diseases.
就目前的技术来说，单纯的采集超声信号，利用超声成像获得的图像可能存在伪像，不能完全准确地反映血管的结构。As far as the current technology is concerned, simply collecting ultrasound signals and using ultrasound imaging to obtain images may have artifacts that cannot completely accurately reflect the structure of blood vessels.
发明内容Summary of the invention
本发明提供了一种信息采集装置，该装置可在血管内采集多种信号，通过多种信号模式成像，可大大提高检测的准确度，避免了对血管检测单纯采集超声信号所获得的图像可能存在伪像，不能完全准确地反映血管内部结构的问题。The present invention provides an information acquisition device, which can collect multiple signals in blood vessels, and use multiple signal modes to image, which can greatly improve the accuracy of detection and avoid the possibility of images obtained by simply collecting ultrasound signals for blood vessel detection. There are artifacts that cannot completely accurately reflect the internal structure of blood vessels.
其具体技术方案如下：The specific technical solutions are as follows:
本发明提供了一种信息采集装置，包括：透明超声探头、激光源、微型CCD图像传感器、第一分立端光纤、第二分立端光纤和自聚焦耦合光纤；The present invention provides an information acquisition device, including: a transparent ultrasonic probe, a laser source, a miniature CCD image sensor, a first discrete end optical fiber, a second discrete end optical fiber, and a self-focusing coupling optical fiber;
所述第一分立端光纤的第一端与激光源连接，第二端与所述自聚焦耦合光纤的第一端通过光纤耦合器连接，所述自聚焦耦合光纤的第二端与所述透明超声探头连接；The first end of the first discrete-end optical fiber is connected to a laser source, the second end is connected to the first end of the self-focusing coupling optical fiber through a fiber coupler, and the second end of the self-focusing coupling optical fiber is connected to the transparent Ultrasound probe connection;
所述第二分立端光纤的第一端与所述微型CCD图像传感器连接，第二端与所述自聚焦耦合光纤的第一端通过光纤耦合器连接；The first end of the second discrete-end optical fiber is connected to the miniature CCD image sensor, and the second end is connected to the first end of the self-focusing coupling optical fiber through an optical fiber coupler;
所述激光源用于发射激光，所述激光经所述第一分立端光纤和所述自聚焦耦合光纤并通过所述透明超声探头照射到待测样品上产生光声信号；The laser source is used to emit laser light, and the laser light is irradiated on the sample to be tested through the first discrete end optical fiber and the self-focusing coupling optical fiber and through the transparent ultrasonic probe to generate a photoacoustic signal;
所述透明超声探头内设置有含稀土的压电元件，所述含稀土的压电元件用于被所述激光激发产生荧光，所述荧光照射到所述待测样品上产生光信号；The transparent ultrasonic probe is provided with a piezoelectric element containing rare earth, and the piezoelectric element containing rare earth is used to be excited by the laser to generate fluorescence, and the fluorescence is irradiated on the sample to be tested to generate an optical signal;
所述透明超声探头用于发射超声波信号并接受所述超声波信号的回波和所述光声信号。The transparent ultrasonic probe is used to transmit an ultrasonic signal and receive the echo of the ultrasonic signal and the photoacoustic signal.
优选地，所述压电元件为含稀土的压电材料。Preferably, the piezoelectric element is a piezoelectric material containing rare earth.
优选地，所述含稀土的压电元件中的稀土元素选自Eu、Er、Pr、Sm、La、Tb、Gd或Lu。Preferably, the rare earth element in the piezoelectric element containing rare earth is selected from Eu, Er, Pr, Sm, La, Tb, Gd or Lu.
优选地，所述含稀土的压电元件中的压电材料选自压电单晶、压电陶瓷或压电陶瓷与聚合物形成的复合材料。Preferably, the piezoelectric material in the piezoelectric element containing rare earths is selected from piezoelectric single crystals, piezoelectric ceramics, or composite materials formed by piezoelectric ceramics and polymers.
优选地，所述待测样品呈腔体状。Preferably, the sample to be tested is in the shape of a cavity.
优选地，所述待测样品包括血管或管道。Preferably, the sample to be tested includes a blood vessel or a pipe.
优选地，还包括：第一成像模块和第二成像模块；Preferably, it further includes: a first imaging module and a second imaging module;
第一成像模块与微型CCD图像传感器连接，第二成像模块与透明超声探头连接。The first imaging module is connected with the micro CCD image sensor, and the second imaging module is connected with the transparent ultrasound probe.
优选地，所述含稀土的压电元件的单元排列方式为单阵元排列、线阵排列或面阵排列。Preferably, the unit arrangement mode of the piezoelectric element containing rare earth is a single array element arrangement, a linear array arrangement or a surface array arrangement.
优选地，所述透明超声探头的形状为凹形或凸形。Preferably, the shape of the transparent ultrasonic probe is concave or convex.
优选地，所述激光源为脉冲激光。Preferably, the laser source is a pulsed laser.
从以上技术方案可以看出，本发明具有以下优点：It can be seen from the above technical solutions that the present invention has the following advantages:
本发明提供了一种信息采集装置，该装置中激光源发射的激光通过第一分立端光纤传输至自聚焦耦合光纤，自聚焦耦合光纤输出的自聚焦激光束透过透明超声探头聚焦在待测样品表面，产生的光声信号被透明超声探头接收。压电元件受激光激发产生荧光，荧光照射到待测样品产生光信号，光信号经自聚焦耦合光纤、第二分立端光纤输出至微型CCD图像传感器， 转换成电信号。透明探头还可以自身发射和接收超声波信号。该装置可采集待测样品的光信号、光声信号和超声波信号，后续对三种信号分析处理成像后即可观测待测样品内部的情况，三种信号成像结果相互比对，优缺互补，可大大提高待测样品检测的准确度。The present invention provides an information acquisition device, in which laser light emitted by a laser source is transmitted to a self-focusing coupling optical fiber through a first discrete end optical fiber, and the self-focusing laser beam output by the self-focusing coupling optical fiber is focused on the object to be measured through a transparent ultrasonic probe On the surface of the sample, the generated photoacoustic signal is received by the transparent ultrasonic probe. The piezoelectric element is excited by the laser to generate fluorescence, and the fluorescence is irradiated to the sample to be tested to generate an optical signal. The optical signal is output to the micro CCD image sensor through the self-focusing coupling optical fiber and the second discrete end optical fiber to be converted into an electrical signal. The transparent probe can also transmit and receive ultrasonic signals by itself. The device can collect the optical signal, photoacoustic signal and ultrasonic signal of the sample to be tested. After the subsequent analysis and processing of the three signals, the internal conditions of the sample to be tested can be observed. The imaging results of the three signals are compared with each other, and the advantages and disadvantages are complementary. It can greatly improve the accuracy of the detection of the sample to be tested.
附图说明Description of the drawings
为了更清楚地说明本发明实施例或现有技术中的技术方案，下面将对实施例或现有技术描述中所需要使用的附图作简单地介绍，显而易见地，下面描述中的附图仅仅是本发明的一些实施例，对于本领域普通技术人员来讲，在不付出创造性劳动性的前提下，还可以根据这些附图获得其它的附图。In order to explain the embodiments of the present invention or the technical solutions in the prior art more clearly, the following will briefly introduce the drawings that need to be used in the description of the embodiments or the prior art. Obviously, the drawings in the following description are only These are some embodiments of the present invention. For those of ordinary skill in the art, other drawings can be obtained based on these drawings without creative labor.
图1为本发明实施例提供的一种信息采集装置的结构示意图；FIG. 1 is a schematic structural diagram of an information collection device provided by an embodiment of the present invention;
其中，图示说明如下：Among them, the illustration is as follows:
1、透明超声探头；2、第一分立端光纤；3、自聚焦耦合光纤；4、微型CCD图像传感器；5、激光源；6、待测样品；7、光纤耦合器；8、第二分立端光纤。1. Transparent ultrasound probe; 2. First discrete end optical fiber; 3. Self-focusing coupling fiber; 4. Miniature CCD image sensor; 5. Laser source; 6. Sample to be tested; 7. Optical fiber coupler; 8. Second discrete End fiber.
具体实施方式Detailed ways
本发明实施例提供了一种信息采集装置，用于解决目前对血管检测单纯的采集超声信号并利用超声成像获得的图像可能存在伪像，不能完全准确地反映血管内部结构的问题。The embodiment of the present invention provides an information acquisition device, which is used to solve the problem that the current blood vessel detection simply collects ultrasound signals and uses ultrasound imaging to obtain images that may have artifacts and cannot completely accurately reflect the internal structure of the blood vessel.
为使得本发明的发明目的、特征、优点能够更加的明显和易懂，下面将对本发明实施例中的技术方案进行清楚、完整地描述，显然，下面所描述的实施例仅仅是本发明一部分实施例，而非全部的实施例。基于本发明中的实施例，本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其它实施例，都属于本发明保护的范围。In order to make the objectives, features, and advantages of the present invention more obvious and understandable, the technical solutions in the embodiments of the present invention will be described clearly and completely below. Obviously, the embodiments described below are only part of the implementation of the present invention. Examples, not all examples. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative work shall fall within the protection scope of the present invention.
本发明提供的一种信息采集装置的一个实施例，包括：透明超声探头1、激光源5、微型CCD图像传感器4、第一分立端光纤2、第二分立端光纤8和自聚焦耦合光纤3；An embodiment of an information acquisition device provided by the present invention includes: a transparent ultrasonic probe 1, a laser source 5, a miniature CCD image sensor 4, a first discrete end optical fiber 2, a second discrete end optical fiber 8 and a self-focusing coupling optical fiber 3 ；
第一分立端光纤2的第一端与激光源5连接，第一分立端光纤2的第二端与自聚焦耦合光纤3的第一端通过光纤耦合器7连接，自聚焦耦合光纤3的第二端与透明超声探头1连接；The first end of the first discrete-end optical fiber 2 is connected to the laser source 5, the second end of the first discrete-end optical fiber 2 and the first end of the self-focusing coupling fiber 3 are connected through the fiber coupler 7, and the first end of the self-focusing coupling fiber 3 is The two ends are connected with the transparent ultrasonic probe 1;
第二分立端光纤8的第一端与微型CCD图像传感器4连接，第二端与自聚焦耦合光纤3的第一端通过光纤耦合器7连接；The first end of the second discrete-end optical fiber 8 is connected to the miniature CCD image sensor 4, and the second end is connected to the first end of the self-focusing coupling optical fiber 3 through an optical fiber coupler 7;
激光源5用于发射激发，激光经第一分立端光纤2和自聚焦耦合光纤3并通过透明超声探头1照射到待测样品6上产生光声信号；透明超声探头1内设置有含稀土的压电元件，含稀土的压电件用于被激光激发后产生荧光，荧光照射到待测样品6上产生光信号；The laser source 5 is used for emission and excitation. The laser is irradiated to the sample 6 to be tested through the first discrete end optical fiber 2 and the self-focusing coupling optical fiber 3, and is irradiated on the sample 6 to generate a photoacoustic signal; the transparent ultrasonic probe 1 is provided with a rare earth-containing Piezoelectric elements, piezoelectric elements containing rare earths are used to generate fluorescence after being excited by laser, and the fluorescence is irradiated on the sample 6 to be tested to generate light signals;
透明超声探头1用于发射超声波信号并接受超声波信号的回波和光声信号；The transparent ultrasonic probe 1 is used to transmit ultrasonic signals and receive echo and photoacoustic signals of ultrasonic signals;
本发明实施例中，激光源5发射的激光通过第一分立端光纤2传输至自聚焦耦合光纤3，自聚焦耦合光纤3输出的自聚焦激光束透过透明超声探头1聚焦在待测样品6表面，产生的光声信号被透明超声探头1接收，然后再传输给外界分析处理进行成像。In the embodiment of the present invention, the laser light emitted by the laser source 5 is transmitted to the self-focusing coupling fiber 3 through the first discrete end optical fiber 2, and the self-focusing laser beam output by the self-focusing coupling fiber 3 is focused on the sample 6 to be tested through the transparent ultrasonic probe 1 On the surface, the generated photoacoustic signal is received by the transparent ultrasonic probe 1, and then transmitted to the outside for analysis and processing for imaging.
透明超声探头1内的含稀土的压电元件受激光激发后会产生荧光，荧光照射到待测样品6，待测样品6上反射的光信号经自聚焦耦合光纤3、第二分立端光纤9输出至微型CCD图像传感器4，转换成电信号。The piezoelectric element containing rare earth in the transparent ultrasonic probe 1 will generate fluorescence after being excited by the laser, and the fluorescence will illuminate the sample 6 to be tested. The light signal reflected on the sample 6 to be tested passes through the self-focusing coupling fiber 3 and the second discrete end fiber 9 It is output to the micro CCD image sensor 4 and converted into an electric signal.
透明探头还可以自身发射和接收超声波信号，然后再传输给外界分析处理进行成像。The transparent probe can also transmit and receive ultrasonic signals by itself, and then transmit them to the outside for analysis and processing for imaging.
本发明实施例提供的信息采集装置可以采集待测样品6的光信号、光声信号和超声波信号，对三种信号进行分析处理成像后可以观测待测样品6内部的情况，大大提高待测样品6检测的准确度。The information collection device provided by the embodiment of the present invention can collect the optical signal, photoacoustic signal and ultrasonic signal of the sample 6 to be tested. After the three signals are analyzed and processed and imaged, the internal condition of the sample 6 to be tested can be observed, which greatly improves the sample to be tested. 6 Accuracy of detection.
本发明实施例中，含稀土的压电元件中的稀土元素选自Eu、Er、Pr、Sm、La、Tb、Gd或Lu。含稀土的压电元件中的压电材料选自压电单晶、压电陶瓷或压电陶瓷与聚合物形成的复合材料。In the embodiment of the present invention, the rare earth element in the piezoelectric element containing rare earth is selected from Eu, Er, Pr, Sm, La, Tb, Gd or Lu. The piezoelectric material in the piezoelectric element containing rare earths is selected from piezoelectric single crystals, piezoelectric ceramics, or composite materials formed by piezoelectric ceramics and polymers.
本发明提供的一种信息采集装置的另一个实施例中，待测样品6呈腔体状。In another embodiment of an information collection device provided by the present invention, the sample 6 to be tested is in the shape of a cavity.
本发明提供的一种信息采集装置的另一个实施例中，待测样品6包括 血管或管道，本实施例中优选为血管。In another embodiment of an information collection device provided by the present invention, the sample 6 to be tested includes a blood vessel or a pipe, and in this embodiment, it is preferably a blood vessel.
本发明还提供了一种信息采集装置的另一个实施例中，含稀土的压电元件的单元排列方式为单阵元排列、线阵排列或面阵排列。The present invention also provides another embodiment of an information acquisition device. In the unit arrangement mode of the piezoelectric element containing rare earth elements is a single array element arrangement, a linear array arrangement or a surface array arrangement.
本发明提供的一种信息采集装置的另一个实施例中，信息采集装置还包括：第一成像模块和第二成像模块；In another embodiment of an information acquisition device provided by the present invention, the information acquisition device further includes: a first imaging module and a second imaging module;
第一成像模块与微型CCD图像传感器4连接，第二成像模块与透明超声探头1连接。The first imaging module is connected with the miniature CCD image sensor 4, and the second imaging module is connected with the transparent ultrasound probe 1.
本发明实施例中，第一成像模块可以实现荧光成像，具体地，光信号经CCD图像传感器4转化为电信号，电信号经过放大，然后转化成数字信号，数字信号经数据处理后形成图像，完成荧光成像。第二成像模块可以实现光声成像和超声波成像，具体地，超声波信号和光声信号转化为电信号，电信号经过放大，然后转化成数字信号，数字信号经数据处理后形成图像，完成超声成像和光声成像。第一成像模块和第二成像模块的成像原理为现有技术，本发明实施例不做赘述。In the embodiment of the present invention, the first imaging module can realize fluorescence imaging. Specifically, the optical signal is converted into an electrical signal by the CCD image sensor 4, the electrical signal is amplified, and then converted into a digital signal, and the digital signal forms an image after data processing. Complete fluorescence imaging. The second imaging module can realize photoacoustic imaging and ultrasound imaging. Specifically, ultrasound signals and photoacoustic signals are converted into electrical signals. The electrical signals are amplified and then converted into digital signals. Acoustic imaging. The imaging principles of the first imaging module and the second imaging module are based on the prior art, and will not be described in detail in the embodiment of the present invention.
本发明实施例提供的信息采集装置利用光声成像的高对比度与超声波成像的高穿透深度，实现准确性高、分辨率好、高还原的成像效果，将光声成像结果与超声波成像结果结合在一起进行分析比对，大大提高了检测的准确度。该装置集光声成像、超声成像和荧光成像于一体，相互对比，优缺互补，成像效果好，大大提高了血管内部的检测精度。The information acquisition device provided by the embodiment of the present invention utilizes the high contrast of photoacoustic imaging and the high penetration depth of ultrasonic imaging to achieve imaging effects of high accuracy, good resolution, and high restoration, and combines the photoacoustic imaging results with the ultrasonic imaging results Performing analysis and comparison together greatly improves the accuracy of detection. The device integrates photoacoustic imaging, ultrasound imaging and fluorescence imaging, and compares each other, complements the advantages and disadvantages, has good imaging effects, and greatly improves the detection accuracy of the inside of blood vessels.
本发明提供的一种信息采集装置的另一个实施例中，透明超声探头1的形状为凹形或凸形。透明超声探头1可以为任意形状，本发明实施例对透明超声探头1的形状不做具体限定。In another embodiment of an information acquisition device provided by the present invention, the shape of the transparent ultrasonic probe 1 is concave or convex. The transparent ultrasonic probe 1 may have any shape, and the embodiment of the present invention does not specifically limit the shape of the transparent ultrasonic probe 1.
本发明提供的一种信息采集装置的另一个实施例中，激光源5为脉冲激光。In another embodiment of an information acquisition device provided by the present invention, the laser source 5 is a pulsed laser.
以上实施例仅用以说明本发明的技术方案，而非对其限制；尽管参照前述实施例对本发明进行了详细的说明，本领域的普通技术人员应当理解：其依然可以对前述各实施例所记载的技术方案进行修改，或者对其中部分技术特征进行等同替换；而这些修改或者替换，并不使相应技术方案的本质脱离本发明各实施例技术方案的精神和范围。The above embodiments are only used to illustrate the technical solutions of the present invention, but not to limit them; although the present invention has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that: The recorded technical solutions are modified, or some of the technical features are equivalently replaced; these modifications or replacements do not cause the essence of the corresponding technical solutions to deviate from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims (9)

  1. 一种信息采集装置，其特征在于，包括：透明超声探头、激光源、微型CCD图像传感器、第一分立端光纤、第二分立端光纤和自聚焦耦合光纤；An information acquisition device, characterized by comprising: a transparent ultrasonic probe, a laser source, a miniature CCD image sensor, a first discrete end optical fiber, a second discrete end optical fiber, and a self-focusing coupling optical fiber;
    所述第一分立端光纤的第一端与激光源连接，第二端与所述自聚焦耦合光纤的第一端通过光纤耦合器连接，所述自聚焦耦合光纤的第二端与所述透明超声探头连接；The first end of the first discrete-end optical fiber is connected to a laser source, the second end is connected to the first end of the self-focusing coupling optical fiber through a fiber coupler, and the second end of the self-focusing coupling optical fiber is connected to the transparent Ultrasound probe connection;
    所述第二分立端光纤的第一端与所述微型CCD图像传感器连接，第二端与所述自聚焦耦合光纤的第一端通过光纤耦合器连接；The first end of the second discrete-end optical fiber is connected to the miniature CCD image sensor, and the second end is connected to the first end of the self-focusing coupling optical fiber through an optical fiber coupler;
    所述激光源用于发射激光，所述激光经所述第一分立端光纤和所述自聚焦耦合光纤并通过所述透明超声探头照射到待测样品上产生光声信号；The laser source is used to emit laser light, and the laser light is irradiated on the sample to be tested through the first discrete end optical fiber and the self-focusing coupling optical fiber and through the transparent ultrasonic probe to generate a photoacoustic signal;
    所述透明超声探头内设置有含稀土的压电元件，所述含稀土的压电元件用于被所述激光激发产生荧光，所述荧光照射到所述待测样品上产生光信号；The transparent ultrasonic probe is provided with a piezoelectric element containing rare earth, and the piezoelectric element containing rare earth is used to be excited by the laser to generate fluorescence, and the fluorescence is irradiated on the sample to be tested to generate an optical signal;
    所述透明超声探头用于发射超声波信号并接受所述超声波信号的回波和所述光声信号。The transparent ultrasonic probe is used to transmit an ultrasonic signal and receive the echo of the ultrasonic signal and the photoacoustic signal.
  2. 根据权利要求1所述的信息采集装置，其特征在于，所述含稀土的压电元件中的稀土元素选自Eu、Er、Pr、Sm、La、Tb、Gd或Lu。The information collection device according to claim 1, wherein the rare earth element in the piezoelectric element containing rare earth is selected from Eu, Er, Pr, Sm, La, Tb, Gd or Lu.
  3. 根据权利要求2所述的信息采集装置，其特征在于，所述含稀土的压电元件中的压电材料选自压电单晶、压电陶瓷或压电陶瓷与聚合物形成的复合材料。The information collection device according to claim 2, wherein the piezoelectric material in the piezoelectric element containing rare earths is selected from piezoelectric single crystals, piezoelectric ceramics, or composite materials formed by piezoelectric ceramics and polymers.
  4. 根据权利要求1所述的信息采集装置，其特征在于，所述待测样品呈腔体状。The information collection device according to claim 1, wherein the sample to be tested is in the shape of a cavity.
  5. 根据权利要求4所述的信息采集装置，其特征在于，所述待测样品包括血管或管道。The information collection device according to claim 4, wherein the sample to be tested comprises a blood vessel or a pipe.
  6. 根据权利要求1所述的信息采集装置，其特征在于，还包括：第一成像模块和第二成像模块；The information acquisition device according to claim 1, further comprising: a first imaging module and a second imaging module;
    第一成像模块与微型CCD图像传感器连接，第二成像模块与透明超声探头连接。The first imaging module is connected with the micro CCD image sensor, and the second imaging module is connected with the transparent ultrasound probe.
  7. 根据权利要求1所述的信息采集装置，其特征在于，所述含稀土的压电元件的单元排列方式为单阵元排列、线阵排列或面阵排列。The information collection device according to claim 1, wherein the unit arrangement of the piezoelectric element containing rare earth is a single array element arrangement, a linear array arrangement, or an area array arrangement.
  8. 根据权利要求1所述的信息采集装置，其特征在于，所述透明超声探头的形状为凹形或凸形。The information collection device according to claim 1, wherein the shape of the transparent ultrasonic probe is concave or convex.
  9. 根据权利要求1所述的信息采集装置，其特征在于，所述激光源为脉冲激光。The information collection device according to claim 1, wherein the laser source is a pulsed laser.
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