WO2021206741A1

WO2021206741A1 - Modulating neurotransmitter concentration

Info

Publication number: WO2021206741A1
Application number: PCT/US2020/035029
Authority: WO
Inventors: Kevin DELAHOUSSAYE
Original assignee: Delahoussaye Kevin
Priority date: 2020-04-09
Filing date: 2020-05-29
Publication date: 2021-10-14

Abstract

Each receptor in question should be bound to only one molecule. The current approach is to create a molecule that 'does it all'. The most effective, efficient, and easy way to modulate the concentration of neurotransmitters in the body is to be specific, one molecule should only bind to one receptor. The current method uses molecules that bind the receptor in many different active sites which does not allow for flexibility or proper and precise modulation. Neuroscience: Each receptor in question should be bound to only one molecule. The current approach is to create a molecule that 'does it all'. The most effective, efficient, and easy way to modulate the concentration of neurotransmitters in the body is to be specific, one molecule should only bind to one receptor. The current method uses molecules that bind the receptor in many different active sites which does not allow for flexibility or proper and precise modulation.

Description

(A) Specification

Modulating Neurotransmitter Concentration

B: Cross Reference to Related Applications: Not Applicable

( C ) Regarding Federally Sponsored Research or Development: Not Applicable

( D): Regarding The Names of The Parties To a Joint Research Agreement: Not Applicable

E: Incorporation by reference of material submitted on a compact disc or as a text file via the The Office Electronic Filing System (EFS-Web):

F: Statement Regarding Prior Disclosures by The Inventor Or a Joint Inventor:

Not Applicable

G: Background of Invention:

(1): Organic Chemistry: As the molecule binds to the active site of the subunit In question and modulates the enzyme to a transition state. (2): Neuroscience: Each receptor in question should be bound to only one molecule. The current approach is to create a molecule that 'does it all'. The most effective, efficient, and easy way to modulate the concentration of neurotransmitters in the body is to be specific, one molecule should only bind to one receptor. The current method uses molecules that bind the receptor in many different active sites which does not allow for flexibility or proper and precise modulation.

(H): Brief Summary of Invention: One molecule should bind to one active site. Molecules that bind to multiple active sites decreases the effectiveness of the molecule to do what we want it to. Modulation of receptors in this way allows for flexibility in adjusting doses, dissociation constants, and joint collaboration with the other molecules being used for a specific purpose. This novel technique introduces specificity into the environment of modulation.

(K): Claim or Claims: See Document "Claims"

(L): Abstract of Disclosure: See Document "Abstract"

(M): Sequence Listing: Not Applicable

Claims

Claims:

I:Using one molecule for one receptor subunit provides greater specificity and flexibility to modulate neurochemistry.

II: Dosages can be adjusted to work in concert with other molecules bound to their receptors.

III: This novel technique allows for the development of better therapies as one molecule is not binding to multiple receptors at a state people cannot control with precision.