WO2021087765A1 - Ultrasonic imaging device and method for detecting endometrial peristalsis - Google Patents

Ultrasonic imaging device and method for detecting endometrial peristalsis Download PDF

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Publication number
WO2021087765A1
WO2021087765A1 PCT/CN2019/115773 CN2019115773W WO2021087765A1 WO 2021087765 A1 WO2021087765 A1 WO 2021087765A1 CN 2019115773 W CN2019115773 W CN 2019115773W WO 2021087765 A1 WO2021087765 A1 WO 2021087765A1
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WO
WIPO (PCT)
Prior art keywords
peristaltic
endometrium
displacement
echo data
creeping
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PCT/CN2019/115773
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French (fr)
Chinese (zh)
Inventor
李双双
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深圳迈瑞生物医疗电子股份有限公司
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Priority to PCT/CN2019/115773 priority Critical patent/WO2021087765A1/en
Priority to CN201980097843.9A priority patent/CN114025672B/en
Publication of WO2021087765A1 publication Critical patent/WO2021087765A1/en
Priority to US17/732,967 priority patent/US20230086624A1/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/08Detecting organic movements or changes, e.g. tumours, cysts, swellings
    • A61B8/0833Detecting organic movements or changes, e.g. tumours, cysts, swellings involving detecting or locating foreign bodies or organic structures
    • A61B8/085Detecting organic movements or changes, e.g. tumours, cysts, swellings involving detecting or locating foreign bodies or organic structures for locating body or organic structures, e.g. tumours, calculi, blood vessels, nodules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/46Ultrasonic, sonic or infrasonic diagnostic devices with special arrangements for interfacing with the operator or the patient
    • A61B8/461Displaying means of special interest
    • A61B8/463Displaying means of special interest characterised by displaying multiple images or images and diagnostic data on one display
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/46Ultrasonic, sonic or infrasonic diagnostic devices with special arrangements for interfacing with the operator or the patient
    • A61B8/467Ultrasonic, sonic or infrasonic diagnostic devices with special arrangements for interfacing with the operator or the patient characterised by special input means
    • A61B8/469Ultrasonic, sonic or infrasonic diagnostic devices with special arrangements for interfacing with the operator or the patient characterised by special input means for selection of a region of interest
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/52Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/5207Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of raw data to produce diagnostic data, e.g. for generating an image
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/52Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/5215Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data
    • A61B8/5223Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for extracting a diagnostic or physiological parameter from medical diagnostic data
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/54Control of the diagnostic device
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/56Details of data transmission or power supply
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/13Tomography
    • A61B8/14Echo-tomography

Definitions

  • the invention relates to the field of medical equipment, in particular to an ultrasonic imaging equipment and a method for detecting endometrial peristalsis.
  • the frequency (such as N times/minute), amplitude, and direction of endometrial peristaltic waves in clinical practice can be used as reference indicators for judging endometrial receptivity, predicting the probability of successful pregnancy, and evaluating embryonic development.
  • the method of ultrasound detection of endometrial peristalsis is mainly through transvaginal ultrasound (TVUS).
  • the doctor observes the changes of the two-dimensional B-mode image in real time for a period of time (such as 1 minute), or the doctor observes the stored B-mode image for a period of time.
  • the video captures the movement information of the endometrium with the naked eye, and judges the amplitude, frequency and direction of the peristaltic wave.
  • this method relies on the doctor’s subjective qualitative judgment, and different doctors may give different judgments; on the other hand, it is difficult for the naked eye to recognize the complicated peristaltic state or the weak peristaltic state, which is not conducive to making Judge accurately.
  • the present invention mainly provides an ultrasonic imaging equipment and a method for detecting endometrial peristalsis.
  • An embodiment provides a method for detecting endometrial peristalsis, including:
  • the peristaltic parameters are displayed.
  • An embodiment provides a method for detecting endometrial peristalsis, including:
  • the peristaltic parameters of the endometrial lining are calculated, wherein the peristaltic parameters are used to describe the peristalsis of the endometrium Motion state
  • the peristaltic parameters are displayed.
  • An embodiment provides a method for detecting endometrial peristalsis, including:
  • the peristaltic parameters of the endometrial lining are calculated, wherein the peristaltic parameters are used to describe the peristalsis of the endometrium Motion state
  • the peristaltic parameters are displayed.
  • An embodiment provides a method for detecting peristalsis of biological tissues, including:
  • the peristaltic parameters are displayed.
  • a method for detecting endometrial peristalsis includes:
  • a method for detecting endometrial peristalsis includes:
  • a method for detecting endometrial peristalsis includes:
  • a method for detecting peristalsis of biological tissue includes:
  • a method for detecting peristalsis of biological tissue includes:
  • An embodiment provides an ultrasound imaging device, including:
  • An ultrasound probe which is used to transmit ultrasonic waves to a region of interest in biological tissues and receive echoes of the ultrasonic waves;
  • the transmitting/receiving circuit is used to control the ultrasonic probe to transmit ultrasonic waves to the endometrium and receive the echo of the ultrasonic waves to obtain ultrasonic echo data;
  • Human-computer interaction device used to receive user input and output visual information
  • a processor configured to obtain an ultrasound image of the endometrium according to the ultrasound echo data; determine the peristaltic displacement or peristaltic velocity of a point in the endometrium within a preset time according to the ultrasound echo data Calculate the peristaltic parameters of the endometrium according to the peristaltic displacement or peristaltic velocity of a point in the endometrium within the preset time period, wherein the peristaltic parameters are used to describe the endometrial peristalsis The state of motion; the peristaltic parameters are displayed through the human-computer interaction device.
  • An embodiment provides an ultrasound imaging device, including:
  • Memory used to store programs
  • the processor is configured to execute the program stored in the memory to implement the above-mentioned method.
  • An embodiment provides a computer-readable storage medium, including a program, which can be executed by a processor to implement the method described above.
  • the peristaltic displacement or peristaltic velocity of a point in the endometrium within a preset period of time is determined by acquiring ultrasound echo data of the endometrium; Calculate the peristaltic parameters of the endometrium according to the peristaltic displacement or peristaltic velocity of points in the endometrium within a preset period of time.
  • the peristaltic parameters are used to describe the movement state of the endometrial peristalsis; the peristaltic parameters are displayed. It realizes the automatic calculation of peristaltic parameters, does not rely on the subjective judgment of the ultrasound doctor, and improves the accuracy and efficiency of peristaltic detection.
  • Figure 1 is a structural block diagram of an ultrasonic imaging device provided by the present invention
  • FIG. 2 is a flowchart of an embodiment of a method for detecting peristalsis of biological tissue provided by the present invention
  • FIG. 3 is a flowchart of an embodiment of a method for detecting peristalsis of biological tissue provided by the present invention
  • FIG. 4 is a flowchart of step 2 in Figure 2;
  • Figure 5 is a schematic diagram of a region of interest in an ultrasound image
  • Fig. 6 is a schematic diagram of a region of interest in an ultrasound image
  • Fig. 7 is a schematic diagram of calculating the creep displacement of a point in a creeping object at different times
  • Figure 8 is a schematic diagram of a region of interest in an ultrasound image
  • Figure 9 is a schematic diagram of a region of interest in an ultrasound image
  • Figure 10 is a schematic diagram of a region of interest in an ultrasound image.
  • connection and “connection” mentioned in this application include direct and indirect connection (connection) unless otherwise specified.
  • the present invention continuously transmits ultrasonic waves to these peristaltic organs or tissues for a period of time and detects echoes, and calculates the difference according to the echo data.
  • the peristaltic displacement or peristaltic speed of an organ or tissue at a time so as to give an objective evaluation of the peristaltic state of the organ or tissue.
  • peristaltic objects are called "peristaltic objects”.
  • the ultrasound imaging equipment provided by the present invention includes an ultrasound probe 30, a transmitting/receiving circuit 40 (ie, a transmitting circuit 410 and a receiving circuit 420), a beam combining module 50, an IQ demodulation module 60, a processor 20, The human-computer interaction device 70 and the memory 80.
  • the ultrasound probe 30 includes a transducer (not shown in the figure) composed of a plurality of array elements arranged in an array.
  • the plurality of array elements are arranged in a row to form a linear array, or arranged in a two-dimensional matrix to form a surface array.
  • the array elements can also form a convex array.
  • the array element is used to transmit an ultrasonic beam according to the excitation electrical signal, or to transform the received ultrasonic beam into an electrical signal. Therefore, each array element can be used to realize the mutual conversion of electrical pulse signals and ultrasonic beams, so as to transmit ultrasonic waves to the object to be imaged (peristaltic objects), and can also be used to receive the echo of the ultrasonic waves reflected by the tissue.
  • the transmitting circuit 410 and the receiving circuit 420 can control which array elements are used to transmit ultrasonic beams and which array elements are used to receive ultrasonic beams, or control the array elements to be used to transmit ultrasonic beams or receive ultrasonic beams in time slots. Echo.
  • the array elements participating in the ultrasonic transmission can be excited by electrical signals at the same time, thereby simultaneously emitting ultrasonic waves; or the array elements participating in the ultrasonic transmission can also be excited by several electrical signals with a certain time interval, so as to continuously emit ultrasonic waves with a certain time interval.
  • the array element uses piezoelectric crystals to convert electrical signals into ultrasonic signals according to the transmission sequence transmitted by the transmitting circuit 410.
  • the ultrasonic signals may include one or more scan pulses, one or more reference pulses, and one or more pushers. Pulse and/or one or more Doppler pulses.
  • the ultrasonic signal includes focused wave and plane wave.
  • the user selects a suitable position and angle by moving the ultrasonic probe 30 to transmit ultrasonic waves to the peristaltic object, that is, the object to be imaged 10, and receives the echo of the ultrasonic wave returned by the object to be imaged 10, and outputs a simulated ultrasonic echo signal, a simulated ultrasonic echo
  • the signal is a channel analog electrical signal formed by taking the receiving array element as the channel, which carries amplitude information, frequency information and time information.
  • the transmitting circuit 410 is used to generate a transmitting sequence according to the control of the processor 20.
  • the transmitting sequence is used to control some or all of the multiple array elements to transmit ultrasonic waves to biological tissues.
  • the parameters of the transmitting sequence include the position of the array element used for transmission, the number of array elements, and Ultrasonic beam transmission parameters (such as amplitude, frequency, number of transmissions, transmission interval, transmission angle, wave type, focus position, etc.).
  • the transmitting circuit 410 is also used to phase delay the transmitted beams, so that different transmitting array elements emit ultrasonic waves at different times, so that each transmitted ultrasonic beam can be focused on a predetermined region of interest.
  • the transmission sequence parameters may be different.
  • the echo signal is received by the receiving circuit 420 and processed by subsequent modules and corresponding algorithms. Generate a B image that reflects the anatomical structure of the tissue, a C image that reflects the anatomical structure of the tissue and blood flow information, and a D image that reflects the Doppler spectrum image.
  • the receiving circuit 420 is used for receiving ultrasonic echo data from the ultrasonic probe 30 and processing the ultrasonic echo data.
  • the receiving circuit 420 may include one or more amplifiers, analog-to-digital converters (ADC), and the like.
  • the amplifier is used to amplify the received echo data after proper gain compensation.
  • the amplifier is used to sample the analog echo data at a predetermined time interval to convert it into digitized data.
  • the digitized echo data still retains the amplitude Information, frequency information and phase information.
  • the data output by the receiving circuit 420 can be output to the beam synthesis module 50 for processing, or output to the memory 80 for storage
  • the beam synthesis module 50 is signal-connected to the receiving circuit 420, and is used for ultrasonic echo data to perform beam synthesis processing such as corresponding delay and weighted summation. Because the distance between the ultrasonic receiving point in the tested tissue and the receiving array element is different, therefore, The channel data of the same receiving point output by different receiving array elements have delay differences, and delay processing is required, the phase is aligned, and the different channel data of the same receiving point are weighted and summed to obtain the ultrasonic echo data after beam synthesis
  • the ultrasonic echo data output by the beam synthesis module 50 is also called radio frequency data (RF data).
  • the beam forming module 50 outputs the radio frequency data to the IQ demodulation module 60. In some embodiments, the beam combining module 50 may also output the radio frequency data to the memory 80 for buffering or storage, or directly output the radio frequency data to the processor 20 for image processing.
  • the beam synthesis module 50 may use hardware, firmware, or software to perform the above functions.
  • the beam synthesis module 50 may include a central controller circuit (CPU) capable of processing input data according to specific logic instructions, one or more micro-processing chips, or Any other electronic components, when the beam combining module 50 is implemented in software, it can execute instructions stored on a tangible and non-transitory computer-readable medium (for example, a memory) to perform beam combining calculations using any appropriate beam combining method .
  • CPU central controller circuit
  • the IQ demodulation module 60 removes the signal carrier through IQ demodulation, extracts the organizational structure information contained in the data, and performs filtering to remove noise.
  • the data obtained at this time is called a baseband signal (IQ data pair).
  • the IQ demodulation module 60 outputs the IQ data pair to the processor 20 for image processing.
  • the IQ demodulation module 60 also buffers or saves the IQ data output to the memory 80, so that the processor 20 reads the data from the memory 80 for subsequent image processing.
  • the IQ demodulation module 60 may also implement the above functions in a manner of hardware, firmware, or software. In some embodiments, the IQ demodulation module 60 and the beam synthesis module 50 may also be integrated into one chip.
  • the processor 20 is configured to be a central controller circuit (CPU), one or more microprocessors, a graphics controller circuit (GPU) or any other electronic components capable of processing input data according to specific logic instructions, which can be configured according to the input Commands or predetermined commands perform control of peripheral electronic components, or perform data reading and/or saving to the memory 80, and input data can also be processed by executing a program in the memory 80, for example, collecting data according to one or more working modes.
  • CPU central controller circuit
  • microprocessors e.g., a graphics controller circuit (GPU) or any other electronic components capable of processing input data according to specific logic instructions, which can be configured according to the input Commands or predetermined commands perform control of peripheral electronic components, or perform data reading and/or saving to the memory 80, and input data can also be processed by executing a program in the memory 80, for example, collecting data according to one or more working modes.
  • GPU graphics controller circuit
  • Perform one or more processing operations on the ultrasound echo data including but not limited to adjusting or limiting the form of ultrasound emitted by the ultrasound probe 30, generating various image frames for subsequent display on the display of the human-computer interaction device 70, or Adjust or limit the content and form displayed on the display, or adjust one or more image display settings displayed on the display (for example, ultrasound images, interface components, locating regions of interest).
  • the collected ultrasound data can be processed by the processor 20 in real time during scanning or treatment, or can be temporarily stored in the memory 80, and processed in a quasi real-time manner in online or offline operation.
  • the processor 20 controls the operation of the transmitting circuit 410 and the receiving circuit 420, for example, controlling the transmitting circuit 410 and the receiving circuit 420 to work alternately or simultaneously.
  • the processor 20 can also determine a suitable working mode according to the user's selection or the setting of the program, form a transmission sequence corresponding to the current working mode, and send the transmission sequence to the transmission circuit 410 so that the transmission circuit 410 adopts a suitable transmission sequence control
  • the ultrasonic probe 30 emits ultrasonic waves.
  • the processor 20 is also used to process the ultrasound echo data to generate a grayscale image of signal strength changes within the scanning range, and the grayscale image reflects the internal anatomical structure of the tissue, which is called a B image.
  • the processor 20 may output the B image to the display of the human-computer interaction device 70 for display.
  • the human-computer interaction device 70 is used for human-computer interaction, that is, receiving user input and outputting visual information; it can receive user input by using a keyboard, operating buttons, mouse, trackball, etc., or a touch integrated with a display. Control screen; its output visual information can use a display.
  • the method for detecting peristalsis of biological tissues is shown in Figs. 2 and 3, and the embodiment shown in Fig. 2 includes the following steps:
  • Step 1 The processor 20 obtains ultrasonic echo data of the peristaltic object 10.
  • Peristalsis objects are biological tissues capable of peristalsis, such as the intestine, stomach, and endometrium. This embodiment takes the endometrium as an example for description.
  • the processing of the electrical signal obtained based on the ultrasonic echo may include data processing links such as analog signal gain compensation, beam synthesis, IQ demodulation, digital signal gain compensation, amplitude calculation, image enhancement, and so on.
  • the ultrasonic echo data of the present invention is the data after data processing is performed on the electric signal obtained based on the echo of the ultrasonic wave when the ultrasonic probe scans the peristaltic object, that is, the ultrasonic echo data can be the data generated in any part of the above-mentioned data processing link.
  • the ultrasound echo data can be analog or digital ultrasound echo data before beam synthesis, or data after beam synthesis, such as the data output by the beam synthesis module 50, or data after IQ demodulation.
  • the data output by the IQ demodulation module 60 may also be ultrasound image data obtained by further processing based on the data after beam synthesis or the data after IQ demodulation.
  • the ultrasonic echo data of the peristaltic object can be obtained from the memory 80, or from the receiving circuit 420, the beam synthesis module 50 or the IQ demodulation module 60.
  • the processor 20 determines the peristaltic displacement or peristaltic velocity of a point in the endometrium within a preset period of time according to the ultrasonic echo data.
  • the preset duration can be determined according to the user's input, or the default value of the ultrasound imaging device can be used, or it can be the scan duration corresponding to the ultrasound echo data.
  • the ultrasonic wave is transmitted for a period of time, and the ultrasonic echo is received, and the ultrasonic echo data is obtained. If the target position is moving, the ultrasonic echo data obtained at different times will change. Based on the correlation method, the change amount or change speed of the ultrasonic echo data at each time can be detected, that is, the creep displacement detection or the speed detection.
  • Step 21 The processor 20 determines the first region of interest according to the ultrasound echo data.
  • the processor 20 generates an ultrasound image reflecting the cut surface of the endometrium according to the ultrasound echo data.
  • the ultrasound image may be dynamic or static, and the ultrasound image may be an ultrasound B image (as shown in FIGS. 5 and 6). It can also be a C image or a three-dimensional ultrasound image.
  • the processor 20 also displays the ultrasound image through the display interface of the human-computer interaction device 70. Determine the first region of interest based on the ultrasound image.
  • the first region of interest may be a region selected by the user through the human-computer interaction device 70, or a region recognized by the processor 20, such as a recognized endometrial region. In other words, one of two ways can be used to determine the first region of interest.
  • Manner 1 The human-computer interaction device 70 receives a region selected by the user on the ultrasound image, and uses the selected region as the first region of interest, such as region A in FIGS. 5, 8, 9 and 10. The user can select the entire endometrial area, or select only a part of the endometrial area as the first area of interest, which is convenient for the user to perform targeted inspections.
  • Manner 2 The processor 20 performs image processing on the ultrasound image, for example, performs boundary recognition through image segmentation technology to obtain the boundary of the endometrium, and uses the area formed by the boundary of the endometrium as the first region of interest, as shown in FIG. 6 Area A and area B in Figure 9. Of course, step 21 is not necessary. In an optional embodiment, this step may not be included, and all regions (ultrasound image field of view) corresponding to the ultrasound echo data are subsequently processed directly.
  • Step 22 The processor 20 detects ultrasound echo data segments of points in the first region of interest or points on the boundary of the first region of interest from the ultrasound echo data at different moments. Specifically, when the first region of interest encompasses the endometrium and regions other than the endometrium, as shown in FIG. 5, ultrasonic echo data segments of points in the first region of interest at different moments are detected. When the first region of interest is the region formed by the boundary of the endometrium, as shown in FIG. 6, the ultrasonic echo data segments of points on the boundary of the endometrium at different moments are detected.
  • Step 23 Select the ultrasonic echo data segment of the detected point at one time, and search in the ultrasonic echo data segment of the other time to find out the correlation with the ultrasonic echo data segment of the selected point (for example, from Correlation or cross-correlation) the largest point, the position of the found point is the position of the selected point at another moment, and the creep displacement of the selected point at these two moments is obtained.
  • the selected point for example, from Correlation or cross-correlation
  • the processor 20 selects a point on the endometrial boundary as the center point from the ultrasound echo data at a moment in time ( Figure 7 left image).
  • Point M in the middle take a piece of one-dimensional data of a fixed size in the Y-axis direction (endometrial thickness direction) of the ultrasound echo data at a time (the solid line segment passing through the M point in the left picture of Fig. 7), as The characteristic information of the endometrial boundary at the current selected point.
  • the same position is taken as the center point (point M in the right image of Fig.
  • the one-dimensional search area in the Y-axis direction (the solid line segment in the right image of Fig. 7) is searched for with the most characteristic information.
  • Match the data segment (the dotted line segment in the right image of Figure 7), and use the center point of the data segment (point N in the right image of Figure 7) as the endometrial boundary at the current moment.
  • the position change of each point between the two moments is the peristaltic displacement of the endometrial boundary at these two moments.
  • creep displacement detection methods based on signal autocorrelation or cross-correlation can also be used to detect creep displacement and creep velocity. It is also possible to detect the peristaltic velocity of points on the border of the endometrium at various moments based on the ultrasound Doppler effect, similar to the principle of conventional blood flow imaging.
  • Step 3 According to the peristaltic displacement or peristaltic velocity of the point obtained in step 2 within a preset period of time, calculate the peristaltic parameters of the endometrium, wherein the peristaltic parameters are used to describe the movement state of the endometrial peristalsis.
  • the peristaltic parameters may include at least one of the amplitude of peristaltic movement, the frequency of peristaltic movement, the total significant peristaltic movement time within a preset period of time, the propagation direction of the peristaltic movement, the propagation speed of the peristaltic movement, the range of the peristaltic movement, and so on.
  • the creep parameters here may also be other parameters that reflect the motion state related to creep displacement or creep speed calculated based on creep displacement or creep speed, such as tissue strain caused by creep, tissue strain rate caused by creep, At least one of acceleration of peristaltic motion and so on.
  • the creeping parameter here may also be at least one statistical quantity of creeping displacement or creeping speed, such as maximum creeping displacement, minimum creeping displacement, mean creeping displacement, creeping displacement variance, maximum creeping speed, minimum creeping speed, The mean value of creeping speed, the variance of creeping speed, and so on.
  • Peristalsis is usually regular, periodic, and propagates from a certain starting point of the endometrium to other locations. It is similar to the propagation of vibration waves. Therefore, peristaltic waves are often used to describe peristalsis in this field.
  • the specific peristaltic parameters mentioned above can be Similar to the parameters of the wave.
  • the preset duration can be selected as the main focus of the clinician, such as 1 minute or 30 seconds, etc. However, a period greater than or equal to the peristalsis is usually selected to ensure that at least one complete peristalsis can be detected.
  • the peristalsis may also be irregular or disordered. Therefore, the aforementioned peristaltic parameters may also be the degree of peristalsis disorder, the degree of unevenness of peristaltic amplitude, the degree of unevenness of peristaltic direction, and the distribution of peristaltic movement in the endometrium, etc., which reflect the irregular or disordered state of peristaltic movement.
  • the peristalsis parameters of the endometrium can be calculated directly based on the peristaltic displacement or peristaltic velocity of the point obtained in step 2 within the preset time; or the peristaltic parameters of the endometrium can be calculated based on the point of the second region of interest.
  • the peristaltic displacement or peristaltic speed within the time period is used to calculate the peristaltic parameters of the endometrium.
  • the second region of interest may be the first region of interest, or it may be an area inside the first region of interest.
  • the calculation of the peristaltic parameters of the endometrium according to the peristaltic displacement or peristaltic velocity of the points of the second region of interest within a preset period of time is taken as an example for description.
  • the second region of interest may be a region selected by the user through the human-computer interaction device 70, or a region recognized by the processor 20, such as a recognized endometrial region.
  • Manner 1 The human-computer interaction device 70 receives the area selected by the user on the ultrasound image, and uses the selected area as the second area of interest, as shown in area B in FIG. 8.
  • the user can select the entire endometrial area in the first area of interest, or only select a part of the endometrial area as the first area of interest, which is convenient for the user to perform targeted inspections.
  • Manner 2 The processor 20 performs image processing on the first region of interest of the ultrasound image, for example, performs boundary recognition through image segmentation technology to obtain the boundary of the endometrium, and uses the region formed by the boundary of the endometrium as the second interest Area, such as area B in Figure 9.
  • the processor 20 generates a creeping displacement and time relationship curve or a creeping speed and time relationship curve according to the creeping displacement or creeping speed of the point of the second region of interest within a preset time period. Calculate at least one of the amplitude, frequency, and total significant movement time within the preset duration according to the relationship curve. Take the relationship curve between creep displacement and time as an example. This curve is similar to a waveform diagram. From this curve, the period of the creep can be obtained, and the frequency (times/min) of the creep can be obtained.
  • the position of the crest or trough on the curve is For the peristaltic amplitude of one peristalsis at a single point corresponding position, the maximum peristaltic amplitude of all points can be taken as the peristaltic amplitude of the endometrium, or the average peristaltic amplitude of all points can be taken as the peristaltic amplitude of the endometrium. Compare whether the maximum creep displacement of each creep is greater than or equal to the preset value.
  • the preset value is a threshold that reflects whether the creep is significant. It can be an empirical value or a value set by the user. All creeps greater than or equal to the preset value are counted. The time it takes to get the total significant exercise time.
  • the processor 20 may also calculate the movement parameter of the point in the second region of interest according to the creeping displacement or creeping speed of the point within a preset time period.
  • the motion parameters include at least one of the maximum creep displacement value, the minimum creep displacement value, the average creep displacement value, and the total significant movement time; the maximum creep displacement value is the maximum creep amplitude within the preset duration, and the minimum creep displacement value is preset The minimum value of the creep amplitude within the duration, and the average creep displacement value is the average value of the creep amplitude within the preset duration.
  • the motion parameter of each point is compared with the size of the preset motion parameter to determine whether the motion parameter of each point reaches the preset motion parameter, and then according to the sequence of each point reaching the preset motion parameter, the propagation direction of the peristalsis is obtained.
  • the processor 20 is also used to determine whether the motion parameter of each point exceeds a preset parameter threshold.
  • the parameter threshold may be the same as or different from the foregoing preset value; the area formed by the point where the motion parameter exceeds the parameter threshold is used as the creep range.
  • the processor 20 obtains the propagation direction of the peristalsis, it is further used to take at least two points in the propagation direction, and obtain the peristaltic motion according to the distance between the selected points in the propagation direction and the time difference between the selected points to reach the preset motion parameters. The speed of propagation.
  • the peristalsis detection method provided by the present invention does not need to rely on the subjective and qualitative judgment of a doctor, and can identify a complex peristaltic state or a weak peristaltic state.
  • the processor 20 displays the peristaltic parameters through the human-computer interaction device 70, for example, displays the values of the peristaltic parameters, such as displaying specific values such as the amplitude, frequency, total significant movement time within a preset period of time, or propagation speed of the peristaltic parameters. Shows the relationship between the amplitude, frequency, total significant movement time or propagation speed of the peristaltic movement within the preset duration, etc. and time. It can also display a schematic diagram of the propagation direction or the range of the peristalsis. The peristalsis parameters are displayed for easy access by the doctor. When displaying the peristaltic parameters, the ultrasound image is displayed at the same time.
  • the processor 20 transmits ultrasonic waves to the peristaltic object 10 by controlling the ultrasonic probe 30, and receives echoes of the ultrasonic waves to obtain ultrasonic echo data.
  • the specific process is shown in step 11 to step 14.
  • Step 11 The processor 20 transmits the first ultrasonic wave to the peristaltic object 10 by controlling the ultrasonic probe 30 and receives the echo of the first ultrasonic wave to obtain the first ultrasonic echo data.
  • Step 12 The processor 20 obtains an ultrasound image of the peristaltic object 10 according to the first ultrasound echo data, for example, according to the first ultrasound echo data, it generates an ultrasound B image reflecting the endometrial section; the specific process has been described in the above content. I won’t go into details here.
  • the processor 20 also displays the acquired ultrasound image through the display interface of the human-computer interaction device 70.
  • Step 13 Determine the region of interest based on the ultrasound image.
  • the region of interest may be a region selected by the user through the human-computer interaction device 70, or a region recognized by the processor 20, such as a recognized endometrial region.
  • Manner 1 The human-computer interaction device 70 receives a region selected by the user on the ultrasound image, and uses the selected region as a region of interest. The user can select the entire endometrial area, or select only a part of the endometrial area as the area of interest, which is convenient for the user to perform targeted inspections.
  • Manner 2 The processor 20 performs image processing on the ultrasound image, for example, performs boundary recognition through image segmentation technology to obtain the boundary of the endometrium, and uses the region formed by the boundary of the endometrium as the region of interest.
  • Step 14 The processor 20 controls the ultrasonic probe 30 to transmit the second ultrasonic wave to the biological tissue corresponding to the region of interest, and receives the echo of the second ultrasonic wave to obtain the second ultrasonic echo data. Obtaining the ultrasound echo data of the region of interest for subsequent processing will be more targeted.
  • the scanning parameters of the second ultrasound can be independent of the first ultrasound, and a higher imaging frame rate can be set to facilitate subsequent peristaltic detection.
  • the detection of peristalsis is a dynamic detection process, so the process of transmitting ultrasonic waves and receiving echoes needs to last for a certain period of time.
  • the first ultrasound is used to generate ultrasound images for display, and the second ultrasound is used for subsequent peristaltic detection.
  • the transmitting and receiving sequences of the second ultrasonic wave and the first ultrasonic wave are different, which means that at least one of the scanning parameters such as the transmitting position, the transmitting frequency, the focusing position, the transmitting time interval, and the transmitting range of the two ultrasonic sequences is different.
  • the scanning range is the user's area of interest, and does not need to cover the user's uninteresting area.
  • the scan frame rate of the second ultrasound can be set higher than that of the first ultrasound, or a detection direction different from that of the first ultrasound imaging can be used.
  • the first ultrasound and the second ultrasound can also be transmitted alternately.
  • the first ultrasonic wave and the second ultrasonic wave can also be the same, that is, the first ultrasonic wave and the second ultrasonic wave share the transmitting and receiving link, the transmitting position, transmitting frequency, focusing position, transmitting time interval, and transmitting range of the ultrasonic sequence
  • the scanning parameters are the same. This method is convenient to implement, saves scanning time, and can generate ultrasound images for doctors to observe while obtaining peristaltic detection results, which is convenient for doctors to compare.
  • a frame of ultrasound B image usually includes the transmission and reception of multiple lateral positions in the field of view, and a series of ultrasound echo data frames can be obtained by repeated transmission.
  • the peristaltic parameters of the endometrium at each time can be obtained, such as peristaltic displacement, peristaltic speed, etc.
  • Step 2' according to the second ultrasonic echo data, determine the creeping displacement or creeping velocity of the points in the region of interest within a preset time period.
  • Step 3' Calculate the creep parameters of the creeping object according to the creeping displacement or creeping speed of the points in the region of interest within a preset period of time, where the creeping parameters are used to describe the movement state of the creeping object.
  • Step 4' display the peristaltic parameters.
  • step 2', step 3', and step 4' are the same as steps 2-4 in the embodiment shown in FIG. 2, so they will not be repeated.
  • the obtained creep displacement or creep speed can be presented to the user in various suitable ways.
  • the size of the creeping displacement and/or the direction of the creeping displacement or the size of the creeping speed and/or the direction of the creeping speed can be displayed; in one embodiment, the creeping displacement or the change of the creeping speed with time can also be displayed.
  • the creep displacement or creep speed can also be mapped to different colors according to its size and/or direction and/or location and/or other properties, to obtain a color map, and display the color map Figure; wait.
  • the program may be stored in a computer-readable storage medium.
  • the storage medium may include: read-only memory, random access memory, magnetic disk, optical disk, hard disk, etc.
  • the computer executes the program to realize the above-mentioned functions.
  • the program is stored in the memory of the device, and when the program in the memory is executed by the processor, all or part of the above functions can be realized.
  • the program can also be stored in a storage medium such as a server, another computer, a magnetic disk, an optical disk, a flash disk, or a mobile hard disk, and saved by downloading or copying.
  • a storage medium such as a server, another computer, a magnetic disk, an optical disk, a flash disk, or a mobile hard disk, and saved by downloading or copying.
  • the program in the memory is executed by the processor, all or part of the functions in the foregoing embodiments can be realized.
  • the principles herein can be reflected in a computer program product on a computer-readable storage medium, which is pre-installed with computer-readable program code.
  • a computer-readable storage medium Any tangible, non-transitory computer-readable storage medium can be used, including magnetic storage devices (hard disks, floppy disks, etc.), optical storage devices (CD-ROM, DVD, Blu Ray disks, etc.), flash memory and/or the like .
  • These computer program instructions can be loaded on a general-purpose computer, a special-purpose computer, or other programmable data processing equipment to form a machine, so that these instructions executed on the computer or other programmable data processing device can generate a device that realizes the specified function.
  • Computer program instructions can also be stored in a computer-readable memory, which can instruct a computer or other programmable data processing equipment to operate in a specific manner, so that the instructions stored in the computer-readable memory can form a piece of Manufactured products, including realizing devices that realize designated functions.
  • Computer program instructions can also be loaded on a computer or other programmable data processing equipment, thereby executing a series of operation steps on the computer or other programmable equipment to produce a computer-implemented process, so that the execution of the computer or other programmable equipment Instructions can provide steps for implementing specified functions.
  • Coupled refers to physical connection, electrical connection, magnetic connection, optical connection, communication connection, functional connection and/or any other connection.

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Abstract

An ultrasonic imaging device and a method for detecting endometrial peristalsis. The method comprises: acquiring ultrasound echo data of the endometrium (1), and determining on said basis the peristaltic displacement or peristaltic speed of a point in the endometrium within a preset period of time (2); calculating peristalsis parameters of the endometrium according to the peristaltic displacement or the peristaltic speed of the point in the endometrium within the preset period of time, the peristalsis parameters being used to describe the moving state of endometrial peristalsis (3); and displaying the peristalsis parameters (4). Thus, peristalsis parameters are calculated automatically without relying on the subjective determination of an ultrasound doctor, which improves the accuracy and efficiency of the detection of peristalsis.

Description

一种超声成像设备和子宫内膜蠕动的检测方法Ultrasonic imaging equipment and method for detecting endometrial peristalsis 技术领域Technical field
本发明涉及医疗器械领域,具体涉及一种超声成像设备和子宫内膜蠕动的检测方法。The invention relates to the field of medical equipment, in particular to an ultrasonic imaging equipment and a method for detecting endometrial peristalsis.
背景技术Background technique
临床中发现,子宫内膜会发生蠕动,且蠕动过程会随着卵泡的生长和***过程发生变化。一些临床研究表明,适当的蠕动可以帮助运送***、提供营养和氧气,过低或者过于激烈的蠕动均有可能降低受孕的成功率。因此,临床中子宫内膜蠕动波的频次(比如N次/分钟)、幅度、方向等可以用作判断子宫内膜容受性、预估受孕成功几率、评价胚胎发育状态的参考指标。It has been found clinically that the endometrium will move, and the course of the movement will change with the growth of follicles and the process of ovulation. Some clinical studies have shown that proper peristalsis can help transport sperm, provide nutrients and oxygen, and that too low or too intense peristalsis may reduce the success rate of conception. Therefore, the frequency (such as N times/minute), amplitude, and direction of endometrial peristaltic waves in clinical practice can be used as reference indicators for judging endometrial receptivity, predicting the probability of successful pregnancy, and evaluating embryonic development.
目前超声检测内膜蠕动的方式主要通过经***超声(TVUS),由医生持续一段时间(比如1分钟)实时观察二维B型图像的变化,或者医生观察所存储的一段时间长度的B型图像视频,肉眼捕捉子宫内膜的运动信息,判断出蠕动波的幅度、频次、方向等。一方面,这种方法依赖于医生的主观定性判断,不同的医生可能给出不同的判断结论;另一方面,对于复杂的蠕动状态,或者微弱的蠕动状态,肉眼很难识别,不利于做出准确判断。At present, the method of ultrasound detection of endometrial peristalsis is mainly through transvaginal ultrasound (TVUS). The doctor observes the changes of the two-dimensional B-mode image in real time for a period of time (such as 1 minute), or the doctor observes the stored B-mode image for a period of time. The video captures the movement information of the endometrium with the naked eye, and judges the amplitude, frequency and direction of the peristaltic wave. On the one hand, this method relies on the doctor’s subjective qualitative judgment, and different doctors may give different judgments; on the other hand, it is difficult for the naked eye to recognize the complicated peristaltic state or the weak peristaltic state, which is not conducive to making Judge accurately.
技术问题technical problem
本发明主要提供一种超声成像设备和子宫内膜蠕动的检测方法。The present invention mainly provides an ultrasonic imaging equipment and a method for detecting endometrial peristalsis.
技术解决方案Technical solutions
一实施例提供一种子宫内膜蠕动的检测方法,包括:An embodiment provides a method for detecting endometrial peristalsis, including:
向子宫内膜发射第一超声波,并接收所述第一超声波的回波,获得第一超声回波数据;Transmitting a first ultrasonic wave to the endometrium and receiving the echo of the first ultrasonic wave to obtain the first ultrasonic echo data;
根据所述第一超声回波数据获得子宫内膜的超声图像;Obtaining an ultrasound image of the endometrium according to the first ultrasound echo data;
根据所述超声图像确定感兴趣区域;Determining a region of interest according to the ultrasound image;
向所述感兴趣区域对应的生物组织发射第二超声波 ,并接收所述第二超声波的回波,获得第二超声回波数据;Transmitting a second ultrasonic wave to the biological tissue corresponding to the region of interest, and receiving an echo of the second ultrasonic wave, to obtain second ultrasonic echo data;
根据所述第二超声回波数据,确定所述感兴趣区域内的点在预设时长内的蠕动位移或蠕动速度;Determine the creep displacement or creep velocity of a point in the region of interest within a preset time period according to the second ultrasonic echo data;
根据所述感兴趣区域内的点在预设时长内的所述蠕动位移或蠕动速度,计算子宫内膜的蠕动参数,其中所述蠕动参数用于描述所述子宫内膜蠕动的运动状态;Calculating the peristaltic parameters of the endometrium according to the peristaltic displacement or peristaltic velocity of points in the region of interest within a preset period of time, where the peristaltic parameters are used to describe the motion state of the endometrial peristalsis;
显示所述蠕动参数。The peristaltic parameters are displayed.
一实施例提供一种子宫内膜蠕动的检测方法,包括:An embodiment provides a method for detecting endometrial peristalsis, including:
向子宫内膜发射超声波,并接收所述超声波的回波,获得超声回波数据;Transmit ultrasonic waves to the endometrium, receive echoes of the ultrasonic waves, and obtain ultrasonic echo data;
根据所述超声回波数据获得所述子宫内膜的超声图像;Obtaining an ultrasound image of the endometrium according to the ultrasound echo data;
根据所述超声回波数据,确定所述子宫内膜中的点在预设时长内的蠕动位移或蠕动速度;Determine the peristaltic displacement or peristaltic velocity of a point in the endometrium within a preset period of time according to the ultrasound echo data;
根据所述子宫内膜中的点在所述预设时长内的所述蠕动位移或蠕动速度,计算所述子宫内膜的蠕动参数,其中所述蠕动参数用于描述所述子宫内膜蠕动的运动状态;According to the peristaltic displacement or peristaltic velocity of a point in the endometrium within the preset period of time, the peristaltic parameters of the endometrial lining are calculated, wherein the peristaltic parameters are used to describe the peristalsis of the endometrium Motion state
显示所述蠕动参数。The peristaltic parameters are displayed.
一实施例提供一种子宫内膜蠕动的检测方法,包括:An embodiment provides a method for detecting endometrial peristalsis, including:
获取子宫内膜的超声回波数据 ; Obtain ultrasound echo data of the endometrium;
根据所述超声回波数据,确定所述子宫内膜中的点在预设时长内的蠕动位移或蠕动速度;Determine the peristaltic displacement or peristaltic velocity of a point in the endometrium within a preset period of time according to the ultrasound echo data;
根据所述子宫内膜中的点在所述预设时长内的所述蠕动位移或蠕动速度,计算所述子宫内膜的蠕动参数,其中所述蠕动参数用于描述所述子宫内膜蠕动的运动状态;According to the peristaltic displacement or peristaltic velocity of a point in the endometrium within the preset period of time, the peristaltic parameters of the endometrial lining are calculated, wherein the peristaltic parameters are used to describe the peristalsis of the endometrium Motion state
显示所述蠕动参数。The peristaltic parameters are displayed.
一实施例提供一种生物组织蠕动的检测方法,包括:An embodiment provides a method for detecting peristalsis of biological tissues, including:
获取蠕动对象的超声回波数据;Acquire ultrasonic echo data of a peristaltic object;
根据所述超声回波数据,确定所述蠕动对象中的点在预设时长内的蠕动位移或蠕动速度;Determine the creep displacement or creep velocity of a point in the peristaltic object within a preset period of time according to the ultrasonic echo data;
根据所述蠕动对象中的点在所述预设时长内的所述蠕动位移或蠕动速度,计算所述蠕动对象的蠕动参数,其中所述蠕动参数用于描述所述蠕动对象蠕动的运动状态;Calculating the peristaltic parameters of the peristaltic object according to the peristaltic displacement or peristaltic velocity of a point in the peristaltic object within the preset time period, where the peristaltic parameters are used to describe the peristaltic motion state of the peristaltic object;
显示所述蠕动参数。The peristaltic parameters are displayed.
一个实施例中,提供了一种子宫内膜蠕动的检测方法,该方法包括:In one embodiment, a method for detecting endometrial peristalsis is provided, and the method includes:
向子宫内膜发射第一超声波,并接收所述第一超声波的回波,获得第一超声回波数据;Transmitting a first ultrasonic wave to the endometrium and receiving the echo of the first ultrasonic wave to obtain the first ultrasonic echo data;
根据所述第一超声回波数据获得子宫内膜的超声图像;Obtaining an ultrasound image of the endometrium according to the first ultrasound echo data;
根据所述超声图像确定感兴趣区域;Determining a region of interest according to the ultrasound image;
向所述感兴趣区域对应的生物组织发射第二超声波,并接收所述第二超声波的回波,获得第二超声回波数据;Transmitting a second ultrasonic wave to the biological tissue corresponding to the region of interest, and receiving an echo of the second ultrasonic wave, to obtain second ultrasonic echo data;
根据所述第二超声回波数据,确定所述感兴趣区域内的子宫内膜的蠕动位移或蠕动速度;Determining the peristaltic displacement or peristaltic velocity of the endometrium in the region of interest according to the second ultrasound echo data;
显示所述蠕动位移或蠕动速度。Display the creeping displacement or creeping speed.
一个实施例中,提供了一种子宫内膜蠕动的检测方法,该方法包括:In one embodiment, a method for detecting endometrial peristalsis is provided, and the method includes:
向子宫内膜发射超声波,并接收所述超声波的回波,获得超声回波数据;Transmit ultrasonic waves to the endometrium, receive echoes of the ultrasonic waves, and obtain ultrasonic echo data;
根据所述超声回波数据获得所述子宫内膜的超声图像;Obtaining an ultrasound image of the endometrium according to the ultrasound echo data;
根据所述超声回波数据,确定所述子宫内膜中的蠕动位移或蠕动速度;Determine the peristaltic displacement or peristaltic velocity in the endometrium according to the ultrasound echo data;
显示所述蠕动位移或蠕动速度。Display the creeping displacement or creeping speed.
一个实施例中,提供了一种子宫内膜蠕动的检测方法,该方法包括:In one embodiment, a method for detecting endometrial peristalsis is provided, and the method includes:
获取子宫内膜的超声回波数据;Obtain ultrasound echo data of the endometrium;
根据所述超声回波数据,确定所述子宫内膜的蠕动位移或蠕动速度;Determine the peristaltic displacement or peristaltic velocity of the endometrium according to the ultrasound echo data;
显示所述蠕动位移或蠕动速度。Display the creeping displacement or creeping speed.
一个实施例中,提供了一种生物组织蠕动的检测方法,该方法包括:In one embodiment, a method for detecting peristalsis of biological tissue is provided, and the method includes:
向蠕动对象发射第一超声波,并接收所述第一超声波的回波,获得第一超声回波数据;Transmitting a first ultrasonic wave to the peristaltic object, and receiving the echo of the first ultrasonic wave, to obtain the first ultrasonic echo data;
根据所述第一超声回波数据获得所述蠕动对象的超声图像;Obtaining an ultrasound image of the peristaltic object according to the first ultrasound echo data;
根据所述超声图像确定感兴趣区域;Determining a region of interest according to the ultrasound image;
向所述感兴趣区域对应的生物组织发射第二超声波,并接收所述第二超声波的回波,获得第二超声回波数据;Transmitting a second ultrasonic wave to the biological tissue corresponding to the region of interest, and receiving an echo of the second ultrasonic wave, to obtain second ultrasonic echo data;
根据所述第二超声回波数据,确定所述感兴趣区域内的蠕动对象的蠕动位移或蠕动速度;Determining the creeping displacement or creeping velocity of the creeping object in the region of interest according to the second ultrasonic echo data;
显示所述蠕动位移或蠕动速度。Display the creeping displacement or creeping speed.
一个实施例中,提供了一种生物组织蠕动的检测方法,该方法包括:In one embodiment, a method for detecting peristalsis of biological tissue is provided, and the method includes:
向蠕动对象发射超声波,并接收所述超声波的回波,获得超声回波数据;Transmit ultrasonic waves to the peristaltic object, receive echoes of the ultrasonic waves, and obtain ultrasonic echo data;
根据所述超声回波数据获得所述蠕动对象的超声图像;Obtaining an ultrasound image of the peristaltic object according to the ultrasound echo data;
根据所述超声回波数据,确定所述蠕动对象的蠕动位移或蠕动速度;Determine the creeping displacement or creeping velocity of the creeping object according to the ultrasonic echo data;
显示所述蠕动位移或蠕动速度。Display the creeping displacement or creeping speed.
一实施例提供一种超声成像设备,包括:An embodiment provides an ultrasound imaging device, including:
超声探头,用于向生物组织内的感兴趣区域发射超声波,并接收所述超声波的回波;An ultrasound probe, which is used to transmit ultrasonic waves to a region of interest in biological tissues and receive echoes of the ultrasonic waves;
发射/接收电路,用于控制超声探头向子宫内膜发射超声波,并接收所述超声波的回波,获得超声回波数据;The transmitting/receiving circuit is used to control the ultrasonic probe to transmit ultrasonic waves to the endometrium and receive the echo of the ultrasonic waves to obtain ultrasonic echo data;
人机交互装置,用于接收用户的输入和输出可视化信息;Human-computer interaction device, used to receive user input and output visual information;
处理器,用于根据所述超声回波数据获得所述子宫内膜的超声图像;根据所述超声回波数据,确定所述子宫内膜中的点在预设时长内的蠕动位移或蠕动速度;根据所述子宫内膜中的点在所述预设时长内的所述蠕动位移或蠕动速度,计算所述子宫内膜的蠕动参数,其中所述蠕动参数用于描述所述子宫内膜蠕动的运动状态;通过所述人机交互装置显示所述蠕动参数。A processor, configured to obtain an ultrasound image of the endometrium according to the ultrasound echo data; determine the peristaltic displacement or peristaltic velocity of a point in the endometrium within a preset time according to the ultrasound echo data Calculate the peristaltic parameters of the endometrium according to the peristaltic displacement or peristaltic velocity of a point in the endometrium within the preset time period, wherein the peristaltic parameters are used to describe the endometrial peristalsis The state of motion; the peristaltic parameters are displayed through the human-computer interaction device.
一实施例提供一种超声成像设备,包括:An embodiment provides an ultrasound imaging device, including:
存储器,用于存储程序;Memory, used to store programs;
处理器,用于执行所述存储器存储的程序以实现如上所述的方法。The processor is configured to execute the program stored in the memory to implement the above-mentioned method.
一实施例提供一种计算机可读存储介质,包括程序,所述程序能够被处理器执行以实现如上所述的方法。An embodiment provides a computer-readable storage medium, including a program, which can be executed by a processor to implement the method described above.
有益效果Beneficial effect
依据上述实施例的超声成像设备和子宫内膜蠕动的检测方法,通过获取子宫内膜的超声回波数据,并以此确定子宫内膜中的点在预设时长内的蠕动位移或蠕动速度;根据子宫内膜中的点在预设时长内的蠕动位移或蠕动速度计算子宫内膜的蠕动参数,其中蠕动参数用于描述子宫内膜蠕动的运动状态;显示蠕动参数。实现了蠕动参数的自动计算,不依赖超声医生的主观判断,提高了蠕动检测的准确性和效率。According to the ultrasonic imaging device and the method for detecting endometrial peristalsis according to the foregoing embodiments, the peristaltic displacement or peristaltic velocity of a point in the endometrium within a preset period of time is determined by acquiring ultrasound echo data of the endometrium; Calculate the peristaltic parameters of the endometrium according to the peristaltic displacement or peristaltic velocity of points in the endometrium within a preset period of time. The peristaltic parameters are used to describe the movement state of the endometrial peristalsis; the peristaltic parameters are displayed. It realizes the automatic calculation of peristaltic parameters, does not rely on the subjective judgment of the ultrasound doctor, and improves the accuracy and efficiency of peristaltic detection.
附图说明Description of the drawings
图1为本发明提供的超声成像设备的结构框图;Figure 1 is a structural block diagram of an ultrasonic imaging device provided by the present invention;
图2为本发明提供的生物组织蠕动的检测方法一实施例的流程图;2 is a flowchart of an embodiment of a method for detecting peristalsis of biological tissue provided by the present invention;
图3为本发明提供的生物组织蠕动的检测方法一实施例的流程图;3 is a flowchart of an embodiment of a method for detecting peristalsis of biological tissue provided by the present invention;
图4为图2中步骤2的流程图;Figure 4 is a flowchart of step 2 in Figure 2;
图5为超声图像中感兴趣区域的示意图;Figure 5 is a schematic diagram of a region of interest in an ultrasound image;
图6为超声图像中感兴趣区域的示意图;Fig. 6 is a schematic diagram of a region of interest in an ultrasound image;
图7为计算蠕动对象中的点在不同时刻下的蠕动位移的示意图;Fig. 7 is a schematic diagram of calculating the creep displacement of a point in a creeping object at different times;
图8为超声图像中感兴趣区域的示意图;Figure 8 is a schematic diagram of a region of interest in an ultrasound image;
图9为超声图像中感兴趣区域的示意图;Figure 9 is a schematic diagram of a region of interest in an ultrasound image;
图10为超声图像中感兴趣区域的示意图。Figure 10 is a schematic diagram of a region of interest in an ultrasound image.
本发明的实施方式Embodiments of the present invention
下面通过具体实施方式结合附图对本发明作进一步详细说明。其中不同实施方式中类似元件采用了相关联的类似的元件标号。在以下的实施方式中,很多细节描述是为了使得本申请能被更好的理解。然而,本领域技术人员可以毫不费力的认识到,其中部分特征在不同情况下是可以省略的,或者可以由其他元件、材料、方法所替代。在某些情况下,本申请相关的一些操作并没有在说明书中显示或者描述,这是为了避免本申请的核心部分被过多的描述所淹没,而对于本领域技术人员而言,详细描述这些相关操作并不是必要的,他们根据说明书中的描述以及本领域的一般技术知识即可完整了解相关操作。Hereinafter, the present invention will be further described in detail through specific embodiments in conjunction with the drawings. Among them, similar elements in different embodiments use related similar element numbers. In the following embodiments, many detailed descriptions are used to make this application better understood. However, those skilled in the art can easily realize that some of the features can be omitted under different circumstances, or can be replaced by other elements, materials, and methods. In some cases, some operations related to this application are not shown or described in the specification. This is to avoid the core part of this application being overwhelmed by excessive descriptions. For those skilled in the art, these are described in detail. Related operations are not necessary, they can fully understand the related operations based on the description in the manual and the general technical knowledge in the field.
另外,说明书中所描述的特点、操作或者特征可以以任意适当的方式结合形成各种实施方式。同时,方法描述中的各步骤或者动作也可以按照本领域技术人员所能显而易见的方式进行顺序调换或调整。因此,说明书和附图中的各种顺序只是为了清楚描述某一个实施例,并不意味着是必须的顺序,除非另有说明其中某个顺序是必须遵循的。In addition, the features, operations, or features described in the specification can be combined in any appropriate manner to form various implementations. At the same time, the steps or actions in the method description can also be sequentially exchanged or adjusted in a manner obvious to those skilled in the art. Therefore, the various sequences in the specification and the drawings are only for the purpose of clearly describing a certain embodiment, and are not meant to be a necessary sequence, unless it is specified that a certain sequence must be followed.
本文中为部件所编序号本身,例如“第一”、“第二”等,仅用于区分所描述的对象,不具有任何顺序或技术含义。而本申请所说“连接”、“联接”,如无特别说明,均包括直接和间接连接(联接)。The serial numbers assigned to the components herein, such as "first", "second", etc., are only used to distinguish the described objects and do not have any sequence or technical meaning. The "connection" and "connection" mentioned in this application include direct and indirect connection (connection) unless otherwise specified.
人体的多种器官或组织存在蠕动现象,例如肠道、胃、子宫内膜等,本发明通过向这些蠕动的器官或组织持续发射一段时间的超声波并检测回波,根据回波数据计算出不同时刻下器官或组织的蠕动位移或蠕动速度,从而对器官或组织的蠕动状态给出客观的评价。具体过程以下将进行详细说明。下文中,主要以测量子宫内膜的蠕动参数为例进行了说明。但是,本领域技术人员应该理解,本发明并不限于子宫内膜,下文的实施例中的方法和设备也适用于测量其他组织的蠕动参数,例如肠道、胃等等。本文中,将这些将要进行蠕动参数测量的蠕动组织称之为“蠕动对象”。There are peristalsis phenomena in various organs or tissues of the human body, such as the intestine, stomach, and endometrium. The present invention continuously transmits ultrasonic waves to these peristaltic organs or tissues for a period of time and detects echoes, and calculates the difference according to the echo data. The peristaltic displacement or peristaltic speed of an organ or tissue at a time, so as to give an objective evaluation of the peristaltic state of the organ or tissue. The specific process will be described in detail below. In the following, the measurement of the peristalsis parameters of the endometrium is mainly used as an example for explanation. However, those skilled in the art should understand that the present invention is not limited to the endometrium, and the methods and devices in the following embodiments are also suitable for measuring peristaltic parameters of other tissues, such as the intestine, stomach, and so on. In this article, these peristaltic tissues that will be measured for peristaltic parameters are called "peristaltic objects".
如图1所示,本发明提供的超声成像设备,包括超声探头30、发射/接收电路40(即发射电路410和接收电路420)、波束合成模块50、IQ解调模块60、处理器20、人机交互装置70和存储器80。As shown in Figure 1, the ultrasound imaging equipment provided by the present invention includes an ultrasound probe 30, a transmitting/receiving circuit 40 (ie, a transmitting circuit 410 and a receiving circuit 420), a beam combining module 50, an IQ demodulation module 60, a processor 20, The human-computer interaction device 70 and the memory 80.
超声探头30包括由阵列式排布的多个阵元组成的换能器(图中未示出),多个阵元排列成一排构成线阵,或排布成二维矩阵构成面阵,多个阵元也可以构成凸阵列。阵元用于根据激励电信号发射超声波束,或将接收的超声波束变换为电信号。因此每个阵元可用于实现电脉冲信号和超声波束的相互转换,从而实现向待成像对象(蠕动对象)发射超声波、也可用于接收经组织反射回的超声波的回波。在进行超声检测时,可通过发射电路410和接收电路420控制哪些阵元用于发射超声波束,哪些阵元用于接收超声波束,或者控制阵元分时隙用于发射超声波束或接收超声波束的回波。参与超声波发射的阵元可以同时被电信号激励,从而同时发射超声波;或者参与超声波发射的阵元也可以被具有一定时间间隔的若干电信号激励,从而持续发射具有一定时间间隔的超声波。The ultrasound probe 30 includes a transducer (not shown in the figure) composed of a plurality of array elements arranged in an array. The plurality of array elements are arranged in a row to form a linear array, or arranged in a two-dimensional matrix to form a surface array. The array elements can also form a convex array. The array element is used to transmit an ultrasonic beam according to the excitation electrical signal, or to transform the received ultrasonic beam into an electrical signal. Therefore, each array element can be used to realize the mutual conversion of electrical pulse signals and ultrasonic beams, so as to transmit ultrasonic waves to the object to be imaged (peristaltic objects), and can also be used to receive the echo of the ultrasonic waves reflected by the tissue. During ultrasonic testing, the transmitting circuit 410 and the receiving circuit 420 can control which array elements are used to transmit ultrasonic beams and which array elements are used to receive ultrasonic beams, or control the array elements to be used to transmit ultrasonic beams or receive ultrasonic beams in time slots. Echo. The array elements participating in the ultrasonic transmission can be excited by electrical signals at the same time, thereby simultaneously emitting ultrasonic waves; or the array elements participating in the ultrasonic transmission can also be excited by several electrical signals with a certain time interval, so as to continuously emit ultrasonic waves with a certain time interval.
阵元例如采用压电晶体,按照发射电路410传输的发射序列将电信号转换成超声信号,根据用途,超声信号可以包括一个或多个扫描脉冲、一个或多个参考脉冲、一个或多个推动脉冲和/或一个或多个多普勒脉冲。根据波的形态,超声信号包括聚焦波和平面波。The array element, for example, uses piezoelectric crystals to convert electrical signals into ultrasonic signals according to the transmission sequence transmitted by the transmitting circuit 410. According to the application, the ultrasonic signals may include one or more scan pulses, one or more reference pulses, and one or more pushers. Pulse and/or one or more Doppler pulses. According to the wave form, the ultrasonic signal includes focused wave and plane wave.
用户通过移动超声探头30选择合适的位置和角度向蠕动对象也就是待成像对象10发射超声波并接收由待成像对象10返回的超声波的回波,输出模拟的超声回波信号,模拟的超声回波信号是按以接收阵元为通道所形成的通道模拟电信号,其携带有幅度信息、频率信息和时间信息。The user selects a suitable position and angle by moving the ultrasonic probe 30 to transmit ultrasonic waves to the peristaltic object, that is, the object to be imaged 10, and receives the echo of the ultrasonic wave returned by the object to be imaged 10, and outputs a simulated ultrasonic echo signal, a simulated ultrasonic echo The signal is a channel analog electrical signal formed by taking the receiving array element as the channel, which carries amplitude information, frequency information and time information.
发射电路410用于根据处理器20的控制产生发射序列,发射序列用于控制多个阵元中的部分或者全部向生物组织发射超声波,发射序列参数包括发射用的阵元位置、阵元数量和超声波束发射参数(例如幅度、频率、发射次数、发射间隔、发射角度、波型、聚焦位置等)。某些情况下,发射电路410还用于对发射的波束进行相位延迟,使不同的发射阵元按照不同的时间发射超声波,以便各发射超声波束能够在预定的感兴趣区域聚焦。不同的工作模式,例如B图像模式、C图像模式和D图像模式(多普勒模式),发射序列参数可能不同,回波信号经接收电路420接收并经后续的模块和相应算法处理后,可生成反映组织解剖结构的B图像、反映组织解剖结构和血流信息的C图像以及反映多普勒频谱图像的D图像。The transmitting circuit 410 is used to generate a transmitting sequence according to the control of the processor 20. The transmitting sequence is used to control some or all of the multiple array elements to transmit ultrasonic waves to biological tissues. The parameters of the transmitting sequence include the position of the array element used for transmission, the number of array elements, and Ultrasonic beam transmission parameters (such as amplitude, frequency, number of transmissions, transmission interval, transmission angle, wave type, focus position, etc.). In some cases, the transmitting circuit 410 is also used to phase delay the transmitted beams, so that different transmitting array elements emit ultrasonic waves at different times, so that each transmitted ultrasonic beam can be focused on a predetermined region of interest. Different working modes, such as B image mode, C image mode and D image mode (Doppler mode), the transmission sequence parameters may be different. The echo signal is received by the receiving circuit 420 and processed by subsequent modules and corresponding algorithms. Generate a B image that reflects the anatomical structure of the tissue, a C image that reflects the anatomical structure of the tissue and blood flow information, and a D image that reflects the Doppler spectrum image.
接收电路420用于从超声探头30接收超声回波数据,并对超声回波数据进行处理。接收电路420可以包括一个或多个放大器、模数转换器(ADC)等。放大器用于在适当增益补偿之后放大所接收到的回波数据,放大器用于对模拟回波数据按预定的时间间隔进行采样,从而转换成数字化的数据,数字化后的回波数据依然保留有幅度信息、频率信息和相位信息。接收电路420输出的数据可输出给波束合成模块50进行处理,或输出给存储器80进行存储The receiving circuit 420 is used for receiving ultrasonic echo data from the ultrasonic probe 30 and processing the ultrasonic echo data. The receiving circuit 420 may include one or more amplifiers, analog-to-digital converters (ADC), and the like. The amplifier is used to amplify the received echo data after proper gain compensation. The amplifier is used to sample the analog echo data at a predetermined time interval to convert it into digitized data. The digitized echo data still retains the amplitude Information, frequency information and phase information. The data output by the receiving circuit 420 can be output to the beam synthesis module 50 for processing, or output to the memory 80 for storage
波束合成模块50和接收电路420信号相连,用于超声回波数据进行相应的延时和加权求和等波束合成处理,由于被测组织中的超声波接收点到接收阵元的距离不同,因此,不同接收阵元输出的同一接收点的通道数据具有延时差异,需要进行延时处理,将相位对齐,并将同一接收点的不同通道数据进行加权求和,得到波束合成后的超声回波数据,波束合成模块50输出的超声回波数据也称为射频数据(RF数据)。波束合成模块50将射频数据输出至IQ解调模块60。在有的实施例中,波束合成模块50也可以将射频数据输出至存储器80进行缓存或保存,或将射频数据直接输出至处理器20进行图像处理。The beam synthesis module 50 is signal-connected to the receiving circuit 420, and is used for ultrasonic echo data to perform beam synthesis processing such as corresponding delay and weighted summation. Because the distance between the ultrasonic receiving point in the tested tissue and the receiving array element is different, therefore, The channel data of the same receiving point output by different receiving array elements have delay differences, and delay processing is required, the phase is aligned, and the different channel data of the same receiving point are weighted and summed to obtain the ultrasonic echo data after beam synthesis The ultrasonic echo data output by the beam synthesis module 50 is also called radio frequency data (RF data). The beam forming module 50 outputs the radio frequency data to the IQ demodulation module 60. In some embodiments, the beam combining module 50 may also output the radio frequency data to the memory 80 for buffering or storage, or directly output the radio frequency data to the processor 20 for image processing.
波束合成模块50可以采用硬件、固件或软件的方式执行上述功能,例如,波束合成模块50可以包括能够根据特定逻辑指令处理输入数据的中央控制器电路(CPU)、一个或多个微处理芯片或其他任何电子部件,当波束合成模块50采用软件方式实现时,其可以执行存储在有形和非暂态计算机可读介质(例如,存储器)上的指令,以使用任何适当波束合成方法进行波束合成计算。The beam synthesis module 50 may use hardware, firmware, or software to perform the above functions. For example, the beam synthesis module 50 may include a central controller circuit (CPU) capable of processing input data according to specific logic instructions, one or more micro-processing chips, or Any other electronic components, when the beam combining module 50 is implemented in software, it can execute instructions stored on a tangible and non-transitory computer-readable medium (for example, a memory) to perform beam combining calculations using any appropriate beam combining method .
IQ解调模块60通过IQ解调去除信号载波,提取数据中包含的组织结构信息,并进行滤波去除噪声,此时获取的数据称为基带信号(IQ数据对)。IQ解调模块60将IQ数据对输出至处理器20进行图像处理。The IQ demodulation module 60 removes the signal carrier through IQ demodulation, extracts the organizational structure information contained in the data, and performs filtering to remove noise. The data obtained at this time is called a baseband signal (IQ data pair). The IQ demodulation module 60 outputs the IQ data pair to the processor 20 for image processing.
在有的实施例中,IQ解调模块60还将IQ数据对输出至存储器80进行缓存或保存,以便处理器20从存储器80中读出数据进行后续的图像处理。In some embodiments, the IQ demodulation module 60 also buffers or saves the IQ data output to the memory 80, so that the processor 20 reads the data from the memory 80 for subsequent image processing.
IQ解调模块60也可以采用硬件、固件或软件的方式执行上述功能,在有的实施例中,IQ解调模块60还可以和波束合成模块50集成在一个芯片中。The IQ demodulation module 60 may also implement the above functions in a manner of hardware, firmware, or software. In some embodiments, the IQ demodulation module 60 and the beam synthesis module 50 may also be integrated into one chip.
处理器20用于配置成能够根据特定逻辑指令处理输入数据的中央控制器电路(CPU)、一个或多个微处理器、图形控制器电路(GPU)或其他任何电子部件,其可以根据输入的指令或预定的指令对***电子部件执行控制,或对存储器80执行数据读取和/或保存,也可以通过执行存储器80中的程序对输入数据进行处理,例如根据一个或多个工作模式对采集的超声回波数据执行一个或多个处理操作,处理操作包括但不限于调整或限定超声探头30发出的超声波的形式,生成各种图像帧以供后续人机交互装置70的显示器进行显示,或者调整或限定在显示器上显示的内容和形式,或者调整在显示器上显示的一个或多个图像显示设置(例如超声图像、界面组件、定位感兴趣区域)。The processor 20 is configured to be a central controller circuit (CPU), one or more microprocessors, a graphics controller circuit (GPU) or any other electronic components capable of processing input data according to specific logic instructions, which can be configured according to the input Commands or predetermined commands perform control of peripheral electronic components, or perform data reading and/or saving to the memory 80, and input data can also be processed by executing a program in the memory 80, for example, collecting data according to one or more working modes. Perform one or more processing operations on the ultrasound echo data, including but not limited to adjusting or limiting the form of ultrasound emitted by the ultrasound probe 30, generating various image frames for subsequent display on the display of the human-computer interaction device 70, or Adjust or limit the content and form displayed on the display, or adjust one or more image display settings displayed on the display (for example, ultrasound images, interface components, locating regions of interest).
接收到回波数据时,所采集的超声数据可由处理器20在扫描或治疗期间实时地处理,也可以临时存储在存储器80上,并且在联机或离线操作中以准实时的方式进行处理。When the echo data is received, the collected ultrasound data can be processed by the processor 20 in real time during scanning or treatment, or can be temporarily stored in the memory 80, and processed in a quasi real-time manner in online or offline operation.
本实施例中,处理器20控制发射电路410和接收电路420的工作,例如控制发射电路410和接收电路420交替工作或同时工作。处理器20还可根据用户的选择或程序的设定确定合适的工作模式,形成与当前工作模式对应的发射序列,并将发射序列发送给发射电路410,以便发射电路410采用合适的发射序列控制超声探头30发射超声波。In this embodiment, the processor 20 controls the operation of the transmitting circuit 410 and the receiving circuit 420, for example, controlling the transmitting circuit 410 and the receiving circuit 420 to work alternately or simultaneously. The processor 20 can also determine a suitable working mode according to the user's selection or the setting of the program, form a transmission sequence corresponding to the current working mode, and send the transmission sequence to the transmission circuit 410 so that the transmission circuit 410 adopts a suitable transmission sequence control The ultrasonic probe 30 emits ultrasonic waves.
处理器20还用于对超声回波数据进行处理,以生成扫描范围内的信号强弱变化的灰度图像,该灰度图像反映组织内部的解剖结构,称为B图像。处理器20可以将B图像输出至人机交互装置70的显示器进行显示。The processor 20 is also used to process the ultrasound echo data to generate a grayscale image of signal strength changes within the scanning range, and the grayscale image reflects the internal anatomical structure of the tissue, which is called a B image. The processor 20 may output the B image to the display of the human-computer interaction device 70 for display.
人机交互装置70用于进行人机交互,即接收用户的输入和输出可视化信息;其接收用户的输入可采用键盘、操作按钮、鼠标、轨迹球等,也可以采用与显示器集成在一起的触控屏;其输出可视化信息可以采用显示器。The human-computer interaction device 70 is used for human-computer interaction, that is, receiving user input and outputting visual information; it can receive user input by using a keyboard, operating buttons, mouse, trackball, etc., or a touch integrated with a display. Control screen; its output visual information can use a display.
基于图1所示的超声成像设备,其对生物组织蠕动的检测方法如图2、图3所示,其中图2所示实施例包括以下步骤:Based on the ultrasonic imaging device shown in Fig. 1, the method for detecting peristalsis of biological tissues is shown in Figs. 2 and 3, and the embodiment shown in Fig. 2 includes the following steps:
步骤1、处理器20获取蠕动对象10的超声回波数据。蠕动对象为能够蠕动的生物组织,例如肠道、胃、子宫内膜等,本实施例以子宫内膜为例进行说明。如上所述,对基于超声波的回波获得的电信号进行的处理可包括模拟信号增益补偿、波束合成、IQ解调、数字信号增益补偿、幅度计算、图像增强等数据处理环节。本发明的超声回波数据是对超声探头扫查蠕动对象时基于超声波的回波得到的电信号进行数据处理后的数据,即超声回波数据可以是上述数据处理环节的任一环节产生的数据。例如,超声回波数据可以是波束合成前的模拟或数字超声回波数据,也可以是经波束合成之后的数据,如波束合成模块50输出的数据,也可以是经IQ解调之后的数据,如IQ解调模块60输出的数据,也可以是基于波束合成后的数据或IQ解调后的数据进一步处理得到的超声图像数据等。换而言之,获取蠕动对象的超声回波数据可以从存储器80中获取,也可以从接收电路420、波束合成模块50或IQ解调模块60中获取。Step 1. The processor 20 obtains ultrasonic echo data of the peristaltic object 10. Peristalsis objects are biological tissues capable of peristalsis, such as the intestine, stomach, and endometrium. This embodiment takes the endometrium as an example for description. As described above, the processing of the electrical signal obtained based on the ultrasonic echo may include data processing links such as analog signal gain compensation, beam synthesis, IQ demodulation, digital signal gain compensation, amplitude calculation, image enhancement, and so on. The ultrasonic echo data of the present invention is the data after data processing is performed on the electric signal obtained based on the echo of the ultrasonic wave when the ultrasonic probe scans the peristaltic object, that is, the ultrasonic echo data can be the data generated in any part of the above-mentioned data processing link. . For example, the ultrasound echo data can be analog or digital ultrasound echo data before beam synthesis, or data after beam synthesis, such as the data output by the beam synthesis module 50, or data after IQ demodulation. For example, the data output by the IQ demodulation module 60 may also be ultrasound image data obtained by further processing based on the data after beam synthesis or the data after IQ demodulation. In other words, the ultrasonic echo data of the peristaltic object can be obtained from the memory 80, or from the receiving circuit 420, the beam synthesis module 50 or the IQ demodulation module 60.
步骤2、处理器20根据超声回波数据,确定子宫内膜中的点在预设时长内的蠕动位移或蠕动速度。预设时长可根据用户的输入来确定,也可以采用超声成像设备的默认值,还可以是超声回波数据对应的扫描时长。对于空间中的某个目标位置,持续一段时间发射超声波,并接收超声回波,得到超声回波数据。如果该目标位置是运动的,则不同时刻所得到的超声回波数据将发生变化。基于相关的方法可以检测出各时刻下超声回波数据的变化量或者变化速度,即为蠕动位移检测或者速度检测。Step 2. The processor 20 determines the peristaltic displacement or peristaltic velocity of a point in the endometrium within a preset period of time according to the ultrasonic echo data. The preset duration can be determined according to the user's input, or the default value of the ultrasound imaging device can be used, or it can be the scan duration corresponding to the ultrasound echo data. For a certain target position in space, the ultrasonic wave is transmitted for a period of time, and the ultrasonic echo is received, and the ultrasonic echo data is obtained. If the target position is moving, the ultrasonic echo data obtained at different times will change. Based on the correlation method, the change amount or change speed of the ultrasonic echo data at each time can be detected, that is, the creep displacement detection or the speed detection.
蠕动位移检测的方式有多种,例如基于block-matching的思路,对于某个时刻的子宫内膜某位置处的超声回波数据段,在另一个时刻的各个不同位置的超声回波数据段进行搜索,找出与之互相关最大的位置,其与原位置的差异,即作为这两个时刻下的该位置的蠕动位移量。具体如图4所示,包括如下步骤:There are many ways to detect peristaltic displacement. For example, based on the idea of block-matching, for the ultrasound echo data segment at a certain position in the endometrium at a certain time, the ultrasonic echo data segment at different positions at another time is performed. Search to find out the position with the greatest mutual correlation, and the difference from the original position is used as the creep displacement of the position at these two moments. As shown in Figure 4, it includes the following steps:
步骤21、处理器20根据超声回波数据确定第一感兴趣区域。例如,处理器20根据超声回波数据生成反映子宫内膜切面的超声图像,超声图像可以是动态的也可以是静态的,超声图像可以是超声B图像(如图5和图6所示),也可以是C图像或三维超声图像等。处理器20还通过人机交互装置70的显示界面显示该超声图像。根据超声图像确定第一感兴趣区域。第一感兴趣区域可以是用户通过人机交互装置70选定的区域,也可以是处理器20识别的区域,例如识别的子宫内膜区域。换而言之,可采用两种方式中的一种来确定第一感兴趣区域。方式一:人机交互装置70接收用户在超声图像上选定的区域,将该选定的区域作为第一感兴趣区域,如图5、8、9和10中的区域A。用户可以选定整个子宫内膜区域,也可以只选取子宫内膜的一部分作为第一感兴趣区域,便于用户进行针对性的检查。方式二:处理器20对超声图像进行图像处理,例如通过图像分割技术进行边界识别,得到子宫内膜的边界,将子宫内膜的边界所形成的区域作为第一感兴趣区域,如图6中的区域A和图9中的区域B。当然,步骤21并不是必须的,在一可选的实施例中可以不包括本步骤,后续直接对超声回波数据对应的所有区域(超声图像视野区域)进行处理。Step 21: The processor 20 determines the first region of interest according to the ultrasound echo data. For example, the processor 20 generates an ultrasound image reflecting the cut surface of the endometrium according to the ultrasound echo data. The ultrasound image may be dynamic or static, and the ultrasound image may be an ultrasound B image (as shown in FIGS. 5 and 6). It can also be a C image or a three-dimensional ultrasound image. The processor 20 also displays the ultrasound image through the display interface of the human-computer interaction device 70. Determine the first region of interest based on the ultrasound image. The first region of interest may be a region selected by the user through the human-computer interaction device 70, or a region recognized by the processor 20, such as a recognized endometrial region. In other words, one of two ways can be used to determine the first region of interest. Manner 1: The human-computer interaction device 70 receives a region selected by the user on the ultrasound image, and uses the selected region as the first region of interest, such as region A in FIGS. 5, 8, 9 and 10. The user can select the entire endometrial area, or select only a part of the endometrial area as the first area of interest, which is convenient for the user to perform targeted inspections. Manner 2: The processor 20 performs image processing on the ultrasound image, for example, performs boundary recognition through image segmentation technology to obtain the boundary of the endometrium, and uses the area formed by the boundary of the endometrium as the first region of interest, as shown in FIG. 6 Area A and area B in Figure 9. Of course, step 21 is not necessary. In an optional embodiment, this step may not be included, and all regions (ultrasound image field of view) corresponding to the ultrasound echo data are subsequently processed directly.
步骤22、处理器20从超声回波数据中检测第一感兴趣区域内的点或第一感兴趣区域边界上的点在不同时刻的超声回波数据段。具体的,当第一感兴趣区域囊括了子宫内膜以及子宫内膜以外的区域时,如图5所示,检测第一感兴趣区域内的点在不同时刻的超声回波数据段。当第一感兴趣区域就是子宫内膜的边界所形成的区域时,如图6所示,则检测子宫内膜的边界上的点在不同时刻的超声回波数据段。Step 22: The processor 20 detects ultrasound echo data segments of points in the first region of interest or points on the boundary of the first region of interest from the ultrasound echo data at different moments. Specifically, when the first region of interest encompasses the endometrium and regions other than the endometrium, as shown in FIG. 5, ultrasonic echo data segments of points in the first region of interest at different moments are detected. When the first region of interest is the region formed by the boundary of the endometrium, as shown in FIG. 6, the ultrasonic echo data segments of points on the boundary of the endometrium at different moments are detected.
步骤23、选取检测到的所述点在一时刻的超声回波数据段,在另一时刻的超声回波数据段中进行搜索,找出与选取点的超声回波数据段相关性(例如自相关或互相关)最大的点,找出的点的位置为选取的点在另一时刻的位置,得到选取的点在这两个时刻下的蠕动位移。Step 23: Select the ultrasonic echo data segment of the detected point at one time, and search in the ultrasonic echo data segment of the other time to find out the correlation with the ultrasonic echo data segment of the selected point (for example, from Correlation or cross-correlation) the largest point, the position of the found point is the position of the selected point at another moment, and the creep displacement of the selected point at these two moments is obtained.
以检测到的点为子宫内膜边界上的点为例,如图7所示,处理器20在一时刻的超声回波数据中选取子宫内膜边界上的一点作为中心点 (图7左图中的M点),在一时刻的超声回波数据的Y轴方向(子宫内膜厚度方向)上取一段固定大小的一维数据(图7左图中穿过M点的实线段),作为当前选取点位置上子宫内膜边界的特征信息。在另一时刻的超声回波数据中以同样位置为中心点(图7右图M点),Y轴方向上的一维搜索区域内(图7右图中的实线段)寻找与特征信息最匹配的数据段(图7右图中的虚线段),并将该数据段的中心点(图7右图中的N点)位置作为当前时刻的子宫内膜边界。两个时刻之间的各点位置变化即为子宫内膜边界在这两个时刻下的蠕动位移。Taking the detected point as a point on the endometrial boundary as an example, as shown in FIG. 7, the processor 20 selects a point on the endometrial boundary as the center point from the ultrasound echo data at a moment in time (Figure 7 left image). Point M in the middle), take a piece of one-dimensional data of a fixed size in the Y-axis direction (endometrial thickness direction) of the ultrasound echo data at a time (the solid line segment passing through the M point in the left picture of Fig. 7), as The characteristic information of the endometrial boundary at the current selected point. In the ultrasound echo data at another moment, the same position is taken as the center point (point M in the right image of Fig. 7), and the one-dimensional search area in the Y-axis direction (the solid line segment in the right image of Fig. 7) is searched for with the most characteristic information. Match the data segment (the dotted line segment in the right image of Figure 7), and use the center point of the data segment (point N in the right image of Figure 7) as the endometrial boundary at the current moment. The position change of each point between the two moments is the peristaltic displacement of the endometrial boundary at these two moments.
步骤24、以此类推得到第一感兴趣区域内的点或第一感兴趣区域边界上的点在预设时长内不同时刻的蠕动位移。蠕动位移与蠕动速度,可以通过d = v*t来换算,即对所述蠕动位移在时间维度上求一阶导数,即可获得蠕动速度,对所述蠕动位移在时间维度上求二阶导数,即可获得加速度。由于蠕动位移和蠕动速度通过计算可以相互转换,本发明不做强调和区分。Step 24: By analogy, the creep displacements of points in the first region of interest or points on the boundary of the first region of interest are obtained at different moments within a preset time period. Creeping displacement and creeping speed can be determined by d = Converted by v*t, that is, the creep velocity is obtained by calculating the first derivative of the creep displacement in the time dimension, and the acceleration is obtained by calculating the second derivative of the creep displacement in the time dimension. Since the creeping displacement and creeping speed can be converted mutually through calculation, the present invention does not emphasize and distinguish them.
当然,在其他实施例中,还可以基于其他基于信号自相关或者互相关的蠕动位移检测方法来实现蠕动位移和蠕动速度的检测。还可以基于超声多普勒效应,以类似常规血流成像的原理,检测出子宫内膜边界上各点在各个时刻的蠕动速度。Of course, in other embodiments, other creep displacement detection methods based on signal autocorrelation or cross-correlation can also be used to detect creep displacement and creep velocity. It is also possible to detect the peristaltic velocity of points on the border of the endometrium at various moments based on the ultrasound Doppler effect, similar to the principle of conventional blood flow imaging.
步骤3、根据步骤2中得到的点在预设时长内的蠕动位移或蠕动速度,计算子宫内膜的蠕动参数,其中蠕动参数用于描述子宫内膜蠕动的运动状态。蠕动参数可以包括蠕动的幅度、蠕动的频次、预设时长内的总显著蠕动运动时间、蠕动运动的传播方向、蠕动运动的传播速度、蠕动运动的范围等等中的至少一种。Step 3. According to the peristaltic displacement or peristaltic velocity of the point obtained in step 2 within a preset period of time, calculate the peristaltic parameters of the endometrium, wherein the peristaltic parameters are used to describe the movement state of the endometrial peristalsis. The peristaltic parameters may include at least one of the amplitude of peristaltic movement, the frequency of peristaltic movement, the total significant peristaltic movement time within a preset period of time, the propagation direction of the peristaltic movement, the propagation speed of the peristaltic movement, the range of the peristaltic movement, and so on.
一个实施例中,这里的蠕动参数也可以是其他基于蠕动位移或蠕动速度计算出的与蠕动位移或蠕动速度相关的反映运动状态的参数,比如蠕动导致的组织应变、蠕动导致的组织应变率、蠕动运动的加速度等等中的至少一种。此外,一个实施例中,这里的蠕动参数也可以是蠕动位移或蠕动速度的至少一个统计量,比如最大蠕动位移、最小蠕动位移、蠕动位移均值、蠕动位移方差、最大蠕动速度、最小蠕动速度、蠕动速度均值、蠕动速度方差等等。In an embodiment, the creep parameters here may also be other parameters that reflect the motion state related to creep displacement or creep speed calculated based on creep displacement or creep speed, such as tissue strain caused by creep, tissue strain rate caused by creep, At least one of acceleration of peristaltic motion and so on. In addition, in an embodiment, the creeping parameter here may also be at least one statistical quantity of creeping displacement or creeping speed, such as maximum creeping displacement, minimum creeping displacement, mean creeping displacement, creeping displacement variance, maximum creeping speed, minimum creeping speed, The mean value of creeping speed, the variance of creeping speed, and so on.
蠕动通常是有规律的,具有周期性,并从子宫内膜的某个起点处传播到其他位置,类似振动波的传播,故本领域也常用蠕动波来描述蠕动,上述具体的蠕动参数可以是类似于波的参数。预设时长可以选择为临床上医生的主要关注时长,比如1分钟或30秒等,但通常选择大于或等于蠕动的周期,以确保能至少检测到一次完整的蠕动。Peristalsis is usually regular, periodic, and propagates from a certain starting point of the endometrium to other locations. It is similar to the propagation of vibration waves. Therefore, peristaltic waves are often used to describe peristalsis in this field. The specific peristaltic parameters mentioned above can be Similar to the parameters of the wave. The preset duration can be selected as the main focus of the clinician, such as 1 minute or 30 seconds, etc. However, a period greater than or equal to the peristalsis is usually selected to ensure that at least one complete peristalsis can be detected.
在一些临床情况下,该蠕动也可能是无规则的或者紊乱的。因此,前述的蠕动参数也可以是蠕动运动的紊乱程度、蠕动幅度的不均匀程度、蠕动方向的不均匀程度和子宫内膜中蠕动运动分布等等反映蠕动运动的不规则或紊乱状态的参数。In some clinical situations, the peristalsis may also be irregular or disordered. Therefore, the aforementioned peristaltic parameters may also be the degree of peristalsis disorder, the degree of unevenness of peristaltic amplitude, the degree of unevenness of peristaltic direction, and the distribution of peristaltic movement in the endometrium, etc., which reflect the irregular or disordered state of peristaltic movement.
同样的,本步骤中,具体可以直接根据步骤2中得到的点在预设时长内的蠕动位移或蠕动速度,计算子宫内膜的蠕动参数;也可以根据第二感兴趣区域的点在预设时长内的蠕动位移或蠕动速度,计算子宫内膜的蠕动参数。第二感兴趣区域可以就是第一感兴趣区域,也可以是第一感兴趣区域内部的一个区域。Similarly, in this step, the peristalsis parameters of the endometrium can be calculated directly based on the peristaltic displacement or peristaltic velocity of the point obtained in step 2 within the preset time; or the peristaltic parameters of the endometrium can be calculated based on the point of the second region of interest. The peristaltic displacement or peristaltic speed within the time period is used to calculate the peristaltic parameters of the endometrium. The second region of interest may be the first region of interest, or it may be an area inside the first region of interest.
本实施例以根据第二感兴趣区域的点在预设时长内的蠕动位移或蠕动速度计算子宫内膜的蠕动参数为例进行说明。同样的,第二感兴趣区域可以是用户通过人机交互装置70选定的区域,也可以是处理器20识别的区域,例如识别的子宫内膜区域。换而言之,可采用两种方式中的一种来确定第二感兴趣区域。方式一:人机交互装置70接收用户在超声图像上选定的区域,将该选定的区域作为第二感兴趣区域,如图8中的区域B。用户可以在第一感兴趣区域内选定整个子宫内膜区域,也可以只选取子宫内膜的一部分作为第一感兴趣区域,便于用户进行针对性的检查。方式二:处理器20对超声图像的第一感兴趣区域进行图像处理,例如通过图像分割技术进行边界识别,得到子宫内膜的边界,将子宫内膜的边界所形成的区域作为第二感兴趣区域,如图9中的区域B。In this embodiment, the calculation of the peristaltic parameters of the endometrium according to the peristaltic displacement or peristaltic velocity of the points of the second region of interest within a preset period of time is taken as an example for description. Similarly, the second region of interest may be a region selected by the user through the human-computer interaction device 70, or a region recognized by the processor 20, such as a recognized endometrial region. In other words, one of two methods can be used to determine the second region of interest. Manner 1: The human-computer interaction device 70 receives the area selected by the user on the ultrasound image, and uses the selected area as the second area of interest, as shown in area B in FIG. 8. The user can select the entire endometrial area in the first area of interest, or only select a part of the endometrial area as the first area of interest, which is convenient for the user to perform targeted inspections. Manner 2: The processor 20 performs image processing on the first region of interest of the ultrasound image, for example, performs boundary recognition through image segmentation technology to obtain the boundary of the endometrium, and uses the region formed by the boundary of the endometrium as the second interest Area, such as area B in Figure 9.
处理器20根据第二感兴趣区域的点在预设时长内的蠕动位移或蠕动速度,生成蠕动位移与时间的关系曲线或蠕动速度与时间的关系曲线。根据关系曲线计算蠕动的幅度、频次、预设时长内的总显著运动时间中的至少一种。以蠕动位移与时间的关系曲线为例,该曲线类似于波形图,从该曲线中即可得到蠕动的周期,从而得到蠕动的频次(次/min),曲线上的波峰或波谷的位置即为单个点对应位置一次蠕动的蠕动幅度,可以取所有点蠕动幅度的最大值作为子宫内膜的蠕动幅度,也可以取所有点蠕动幅度的平均值作为子宫内膜的蠕动幅度。比较每次蠕动的最大蠕动位移是否大于或等于预设值,预设值为反映蠕动是否显著的一个阈值,可以是经验值或用户设定的一个值,统计大于或等于预设值的所有蠕动所花费的时间,得到总显著运动时间。The processor 20 generates a creeping displacement and time relationship curve or a creeping speed and time relationship curve according to the creeping displacement or creeping speed of the point of the second region of interest within a preset time period. Calculate at least one of the amplitude, frequency, and total significant movement time within the preset duration according to the relationship curve. Take the relationship curve between creep displacement and time as an example. This curve is similar to a waveform diagram. From this curve, the period of the creep can be obtained, and the frequency (times/min) of the creep can be obtained. The position of the crest or trough on the curve is For the peristaltic amplitude of one peristalsis at a single point corresponding position, the maximum peristaltic amplitude of all points can be taken as the peristaltic amplitude of the endometrium, or the average peristaltic amplitude of all points can be taken as the peristaltic amplitude of the endometrium. Compare whether the maximum creep displacement of each creep is greater than or equal to the preset value. The preset value is a threshold that reflects whether the creep is significant. It can be an empirical value or a value set by the user. All creeps greater than or equal to the preset value are counted. The time it takes to get the total significant exercise time.
在一可选的实施例中,还可以由处理器20根据第二感兴趣区域的点在预设时长内的蠕动位移或蠕动速度,计算得到所述点的运动参数。运动参数包括最大蠕动位移值、最小蠕动位移值、平均蠕动位移值、总显著运动时间中的至少一种;最大蠕动位移值为预设时长内蠕动幅度的最大值,最小蠕动位移值为预设时长内蠕动幅度的最小值,平均蠕动位移值为预设时长内蠕动幅度的平均值。比较各个点的运动参数与预设运动参数的大小,以判断各个点的运动参数是否达到预设运动参数,进而根据各个点到达预设运动参数的先后顺序,得到蠕动的传播方向。处理器20还用于判断各个点的运动参数是否超过预设的参数阈值,该参数阈值可以与上述预设值相同, 也可以不同;将运动参数超过参数阈值的点形成的区域作为蠕动范围。In an optional embodiment, the processor 20 may also calculate the movement parameter of the point in the second region of interest according to the creeping displacement or creeping speed of the point within a preset time period. The motion parameters include at least one of the maximum creep displacement value, the minimum creep displacement value, the average creep displacement value, and the total significant movement time; the maximum creep displacement value is the maximum creep amplitude within the preset duration, and the minimum creep displacement value is preset The minimum value of the creep amplitude within the duration, and the average creep displacement value is the average value of the creep amplitude within the preset duration. The motion parameter of each point is compared with the size of the preset motion parameter to determine whether the motion parameter of each point reaches the preset motion parameter, and then according to the sequence of each point reaching the preset motion parameter, the propagation direction of the peristalsis is obtained. The processor 20 is also used to determine whether the motion parameter of each point exceeds a preset parameter threshold. The parameter threshold may be the same as or different from the foregoing preset value; the area formed by the point where the motion parameter exceeds the parameter threshold is used as the creep range.
进一步的,处理器20得到蠕动的传播方向之后,还用于在传播方向上取至少两个点,根据传播方向上选取的点的间距以及选取点之间到达预设运动参数的时间差,得到蠕动的传播速度。Further, after the processor 20 obtains the propagation direction of the peristalsis, it is further used to take at least two points in the propagation direction, and obtain the peristaltic motion according to the distance between the selected points in the propagation direction and the time difference between the selected points to reach the preset motion parameters. The speed of propagation.
可见,本发明提供的蠕动检测方法,无需依赖医生的主观定性判断,能对复杂的蠕动状态或者微弱的蠕动状态进行识别。It can be seen that the peristalsis detection method provided by the present invention does not need to rely on the subjective and qualitative judgment of a doctor, and can identify a complex peristaltic state or a weak peristaltic state.
步骤4、处理器20通过人机交互装置70显示蠕动参数,例如显示蠕动参数的数值,如显示蠕动的幅度、频次、预设时长内的总显著运动时间或传播速度等的具体数值,也可以显示蠕动的幅度、频次、预设时长内的总显著运动时间或传播速度等与时间的关系曲线。也可以显示传播方向或蠕动范围的示意图。将蠕动参数显示出来,便于医生获取。在显示蠕动参数时,同时显示超声图像。Step 4. The processor 20 displays the peristaltic parameters through the human-computer interaction device 70, for example, displays the values of the peristaltic parameters, such as displaying specific values such as the amplitude, frequency, total significant movement time within a preset period of time, or propagation speed of the peristaltic parameters. Shows the relationship between the amplitude, frequency, total significant movement time or propagation speed of the peristaltic movement within the preset duration, etc. and time. It can also display a schematic diagram of the propagation direction or the range of the peristalsis. The peristalsis parameters are displayed for easy access by the doctor. When displaying the peristaltic parameters, the ultrasound image is displayed at the same time.
图3所示的实施例中,处理器20通过控制超声探头30向蠕动对象10发射超声波,并接收超声波的回波,获得超声回波数据。具体过程如步骤11-步骤14所示。In the embodiment shown in FIG. 3, the processor 20 transmits ultrasonic waves to the peristaltic object 10 by controlling the ultrasonic probe 30, and receives echoes of the ultrasonic waves to obtain ultrasonic echo data. The specific process is shown in step 11 to step 14.
步骤11、处理器20通过控制超声探头30向蠕动对象10发射第一超声波,并接收第一超声波的回波,获得第一超声回波数据。Step 11. The processor 20 transmits the first ultrasonic wave to the peristaltic object 10 by controlling the ultrasonic probe 30 and receives the echo of the first ultrasonic wave to obtain the first ultrasonic echo data.
步骤12、处理器20根据第一超声回波数据获得蠕动对象10的超声图像,例如根据第一超声回波数据生成反映子宫内膜切面的超声B图像;具体过程在上述内容中已阐述,在此不做赘述。处理器20还通过人机交互装置70的显示界面显示获得的超声图像。Step 12. The processor 20 obtains an ultrasound image of the peristaltic object 10 according to the first ultrasound echo data, for example, according to the first ultrasound echo data, it generates an ultrasound B image reflecting the endometrial section; the specific process has been described in the above content. I won’t go into details here. The processor 20 also displays the acquired ultrasound image through the display interface of the human-computer interaction device 70.
步骤13、根据超声图像确定感兴趣区域。感兴趣区域可以是用户通过人机交互装置70选定的区域,也可以是处理器20识别的区域,例如识别的子宫内膜区域。换而言之,可采用两种方式中的一种来确定感兴趣区域。方式一:人机交互装置70接收用户在超声图像上选定的区域,将该选定的区域作为感兴趣区域。用户可以选定整个子宫内膜区域,也可以只选取子宫内膜的一部分作为感兴趣区域,便于用户进行针对性的检查。方式二:处理器20对超声图像进行图像处理,例如通过图像分割技术进行边界识别,得到子宫内膜的边界,将子宫内膜的边界所形成的区域作为感兴趣区域。Step 13. Determine the region of interest based on the ultrasound image. The region of interest may be a region selected by the user through the human-computer interaction device 70, or a region recognized by the processor 20, such as a recognized endometrial region. In other words, one of two ways can be used to determine the region of interest. Manner 1: The human-computer interaction device 70 receives a region selected by the user on the ultrasound image, and uses the selected region as a region of interest. The user can select the entire endometrial area, or select only a part of the endometrial area as the area of interest, which is convenient for the user to perform targeted inspections. Manner 2: The processor 20 performs image processing on the ultrasound image, for example, performs boundary recognition through image segmentation technology to obtain the boundary of the endometrium, and uses the region formed by the boundary of the endometrium as the region of interest.
步骤14、处理器20通过控制超声探头30向感兴趣区域对应的生物组织发射第二超声波,并接收第二超声波的回波,获得第二超声回波数据。获取感兴趣区域的超声回波数据进行后续处理,将更具有针对性。并且第二超声波的扫描参数可以独立于第一超声波,可设置更高的成像帧率,便于后续的蠕动检测。Step 14. The processor 20 controls the ultrasonic probe 30 to transmit the second ultrasonic wave to the biological tissue corresponding to the region of interest, and receives the echo of the second ultrasonic wave to obtain the second ultrasonic echo data. Obtaining the ultrasound echo data of the region of interest for subsequent processing will be more targeted. In addition, the scanning parameters of the second ultrasound can be independent of the first ultrasound, and a higher imaging frame rate can be set to facilitate subsequent peristaltic detection.
对蠕动的检测是一个动态检测的过程,所以发射超声波与接收回波的过程需持续一定的时间。The detection of peristalsis is a dynamic detection process, so the process of transmitting ultrasonic waves and receiving echoes needs to last for a certain period of time.
本实施例中,第一超声波用来生成超声图像以显示,第二超声波用来进行后续的蠕动检测。第二超声波与第一超声波的发射接收序列不同,这意味着两者超声序列的发射位置、发射频率、聚焦位置、发射时间间隔、发射范围等扫描参数中的至少一个不同。扫描的范围为用户的感兴趣区域,而不需要覆盖用户不感兴趣的区域。为了获得更精细的运动状态,可以设定第二超声波的扫描帧率高于第一超声波的扫描帧率,或者采用与第一超声波成像不同的检测方向。In this embodiment, the first ultrasound is used to generate ultrasound images for display, and the second ultrasound is used for subsequent peristaltic detection. The transmitting and receiving sequences of the second ultrasonic wave and the first ultrasonic wave are different, which means that at least one of the scanning parameters such as the transmitting position, the transmitting frequency, the focusing position, the transmitting time interval, and the transmitting range of the two ultrasonic sequences is different. The scanning range is the user's area of interest, and does not need to cover the user's uninteresting area. In order to obtain a finer motion state, the scan frame rate of the second ultrasound can be set higher than that of the first ultrasound, or a detection direction different from that of the first ultrasound imaging can be used.
此时,为了在进行蠕动检测时同步观察超声图像,还可以交替的进行第一超声波、第二超声波的发射。当然,也可以在时间方向进行插值,获得更多时刻的帧数据。At this time, in order to simultaneously observe the ultrasound image during the peristaltic detection, the first ultrasound and the second ultrasound can also be transmitted alternately. Of course, it is also possible to perform interpolation in the time direction to obtain frame data at more moments.
一种可选的实施例,第一超声波与第二超声波还可以相同,即第一超声波与第二超声波共用发射接收环节,超声序列的发射位置、发射频率、聚焦位置、发射时间间隔、发射范围等扫描参数均相同。此方式实施方便,节省了扫描时间,可以一边生成超声图像供医生观察,一边获得蠕动的检测结果,方便医生对比。以超声图像为超声B图像为例,一帧超声B图像通常包括视野里的多个横向位置的发射接收,通过重复发射可以获得一系列超声回波数据帧。一方面,对超声回波数据进行B数据处理,可以获得一系列超声B图像,通过观察超B图像,医生可以看到子宫内膜的位置、形态、运动;另一方面,对超声回波数据进行蠕动波检测处理(过程见图2所示的实施例),可以获得各个时刻下子宫内膜的蠕动参数,比如蠕动位移量、蠕动速度等。An optional embodiment, the first ultrasonic wave and the second ultrasonic wave can also be the same, that is, the first ultrasonic wave and the second ultrasonic wave share the transmitting and receiving link, the transmitting position, transmitting frequency, focusing position, transmitting time interval, and transmitting range of the ultrasonic sequence The scanning parameters are the same. This method is convenient to implement, saves scanning time, and can generate ultrasound images for doctors to observe while obtaining peristaltic detection results, which is convenient for doctors to compare. Taking an ultrasound image as an ultrasound B image as an example, a frame of ultrasound B image usually includes the transmission and reception of multiple lateral positions in the field of view, and a series of ultrasound echo data frames can be obtained by repeated transmission. On the one hand, by performing B data processing on the ultrasound echo data, a series of ultrasound B images can be obtained. By observing the ultrasound B images, the doctor can see the position, shape, and movement of the endometrium; on the other hand, the ultrasound echo data Performing the peristaltic wave detection processing (see the embodiment shown in Figure 2 for the process), the peristaltic parameters of the endometrium at each time can be obtained, such as peristaltic displacement, peristaltic speed, etc.
步骤2’、根据第二超声回波数据,确定感兴趣区域内的点在预设时长内的蠕动位移或蠕动速度。Step 2', according to the second ultrasonic echo data, determine the creeping displacement or creeping velocity of the points in the region of interest within a preset time period.
步骤3’、根据感兴趣区域内的点在预设时长内的蠕动位移或蠕动速度,计算蠕动对象的蠕动参数,其中蠕动参数用于描述蠕动对象蠕动的运动状态。Step 3': Calculate the creep parameters of the creeping object according to the creeping displacement or creeping speed of the points in the region of interest within a preset period of time, where the creeping parameters are used to describe the movement state of the creeping object.
步骤4’、显示蠕动参数。Step 4', display the peristaltic parameters.
其中,步骤2’、步骤3’和步骤4’与图2所示实施例中的步骤2-4相同,故不赘述。Among them, step 2', step 3', and step 4'are the same as steps 2-4 in the embodiment shown in FIG. 2, so they will not be repeated.
本发明的一些实施例中,在如上述实施例中一样获得了蠕动对象(例如,子宫内膜)的位移(称之为蠕动位移)或速度(称之为蠕动速度)之后,也可以不在另外计算蠕动参数,而是直接显示获得的蠕动位移或蠕动速度,即可以用各种适合的方式将获得的蠕动位移或蠕动速度呈现给用户。例如,一个实施例中,可以显示蠕动位移的大小和/或蠕动位移的方向或者显示蠕动速度的大小和/或蠕动速度的方向;一个实施例中,也可以显示蠕动位移或蠕动速度随时间变化的曲线图;一个实施例中,也可以将蠕动位移或蠕动速度按照其大小和/或方向和/或所在位置和/或其他性质映射为不同的颜色,获得彩色映射图,并显示该彩色映射图;等等。In some embodiments of the present invention, after obtaining the displacement (referred to as peristaltic displacement) or velocity (referred to as peristaltic velocity) of the peristaltic object (for example, the endometrium) as in the above-mentioned embodiment, it is not necessary to separately Calculate the creep parameters, but directly display the obtained creep displacement or creep speed, that is, the obtained creep displacement or creep speed can be presented to the user in various suitable ways. For example, in one embodiment, the size of the creeping displacement and/or the direction of the creeping displacement or the size of the creeping speed and/or the direction of the creeping speed can be displayed; in one embodiment, the creeping displacement or the change of the creeping speed with time can also be displayed. In one embodiment, the creep displacement or creep speed can also be mapped to different colors according to its size and/or direction and/or location and/or other properties, to obtain a color map, and display the color map Figure; wait.
本领域技术人员可以理解,上述实施方式中各种方法的全部或部分功能可以通过硬件的方式实现,也可以通过计算机程序的方式实现。当上述实施方式中全部或部分功能通过计算机程序的方式实现时,该程序可以存储于一计算机可读存储介质中,存储介质可以包括:只读存储器、随机存储器、磁盘、光盘、硬盘等,通过计算机执行该程序以实现上述功能。例如,将程序存储在设备的存储器中,当通过处理器执行存储器中程序,即可实现上述全部或部分功能。另外,当上述实施方式中全部或部分功能通过计算机程序的方式实现时,该程序也可以存储在服务器、另一计算机、磁盘、光盘、闪存盘或移动硬盘等存储介质中,通过下载或复制保存到本地设备的存储器中,或对本地设备的***进行版本更新,当通过处理器执行存储器中的程序时,即可实现上述实施方式中全部或部分功能。 Those skilled in the art can understand that all or part of the functions of the various methods in the above-mentioned embodiments can be realized by hardware or by computer programs. When all or part of the functions in the above embodiments are realized by a computer program, the program may be stored in a computer-readable storage medium. The storage medium may include: read-only memory, random access memory, magnetic disk, optical disk, hard disk, etc. The computer executes the program to realize the above-mentioned functions. For example, the program is stored in the memory of the device, and when the program in the memory is executed by the processor, all or part of the above functions can be realized. In addition, when all or part of the functions in the above embodiments are implemented by a computer program, the program can also be stored in a storage medium such as a server, another computer, a magnetic disk, an optical disk, a flash disk, or a mobile hard disk, and saved by downloading or copying. In the memory of the local device, or update the version of the system of the local device, when the program in the memory is executed by the processor, all or part of the functions in the foregoing embodiments can be realized.
本文参照了各种示范实施例进行说明。然而,本领域的技术人员将认识到,在不脱离本文范围的情况下,可以对示范性实施例做出改变和修正。例如,各种操作步骤以及用于执行操作步骤的组件,可以根据特定的应用或考虑与***的操作相关联的任何数量的成本函数以不同的方式实现(例如一个或多个步骤可以被删除、修改或结合到其他步骤中)。This document is described with reference to various exemplary embodiments. However, those skilled in the art will recognize that changes and modifications can be made to the exemplary embodiments without departing from the scope of this document. For example, various operation steps and components used to perform the operation steps can be implemented in different ways according to specific applications or considering any number of cost functions associated with the operation of the system (for example, one or more steps can be deleted, Modify or incorporate into other steps).
另外,如本领域技术人员所理解的,本文的原理可以反映在计算机可读存储介质上的计算机程序产品中,该可读存储介质预装有计算机可读程序代码。任何有形的、非暂时性的计算机可读存储介质皆可被使用,包括磁存储设备(硬盘、软盘等)、光学存储设备(CD-ROM、DVD、Blu Ray盘等)、闪存和/或诸如此类。这些计算机程序指令可被加载到通用计算机、专用计算机或其他可编程数据处理设备上以形成机器,使得这些在计算机上或其他可编程数据处理装置上执行的指令可以生成实现指定的功能的装置。这些计算机程序指令也可以存储在计算机可读存储器中,该计算机可读存储器可以指示计算机或其他可编程数据处理设备以特定的方式运行,这样存储在计算机可读存储器中的指令就可以形成一件制造品,包括实现指定功能的实现装置。计算机程序指令也可以加载到计算机或其他可编程数据处理设备上,从而在计算机或其他可编程设备上执行一系列操作步骤以产生一个计算机实现的进程,使得在计算机或其他可编程设备上执行的指令可以提供用于实现指定功能的步骤。In addition, as understood by those skilled in the art, the principles herein can be reflected in a computer program product on a computer-readable storage medium, which is pre-installed with computer-readable program code. Any tangible, non-transitory computer-readable storage medium can be used, including magnetic storage devices (hard disks, floppy disks, etc.), optical storage devices (CD-ROM, DVD, Blu Ray disks, etc.), flash memory and/or the like . These computer program instructions can be loaded on a general-purpose computer, a special-purpose computer, or other programmable data processing equipment to form a machine, so that these instructions executed on the computer or other programmable data processing device can generate a device that realizes the specified function. These computer program instructions can also be stored in a computer-readable memory, which can instruct a computer or other programmable data processing equipment to operate in a specific manner, so that the instructions stored in the computer-readable memory can form a piece of Manufactured products, including realizing devices that realize designated functions. Computer program instructions can also be loaded on a computer or other programmable data processing equipment, thereby executing a series of operation steps on the computer or other programmable equipment to produce a computer-implemented process, so that the execution of the computer or other programmable equipment Instructions can provide steps for implementing specified functions.
虽然在各种实施例中已经示出了本文的原理,但是许多特别适用于特定环境和操作要求的结构、布置、比例、元件、材料和部件的修改可以在不脱离本披露的原则和范围内使用。以上修改和其他改变或修正将被包含在本文的范围之内。Although the principles herein have been shown in various embodiments, many modifications to the structure, arrangement, proportions, elements, materials, and components that are particularly suitable for specific environments and operating requirements can be made without departing from the principles and scope of this disclosure. use. The above modifications and other changes or amendments will be included in the scope of this article.
前述具体说明已参照各种实施例进行了描述。然而,本领域技术人员将认识到,可以在不脱离本披露的范围的情况下进行各种修正和改变。因此,对于本披露的考虑将是说明性的而非限制性的意义上的,并且所有这些修改都将被包含在其范围内。同样,有关于各种实施例的优点、其他优点和问题的解决方案已如上所述。然而,益处、优点、问题的解决方案以及任何能产生这些的要素,或使其变得更明确的解决方案都不应被解释为关键的、必需的或必要的。本文中所用的术语“包括”和其任何其他变体,皆属于非排他性包含,这样包括要素列表的过程、方法、文章或设备不仅包括这些要素,还包括未明确列出的或不属于该过程、方法、***、文章或设备的其他要素。此外,本文中所使用的术语“耦合”和其任何其他变体都是指物理连接、电连接、磁连接、光连接、通信连接、功能连接和/或任何其他连接。The foregoing detailed description has been described with reference to various embodiments. However, those skilled in the art will recognize that various modifications and changes can be made without departing from the scope of this disclosure. Therefore, the consideration of this disclosure will be in an illustrative rather than restrictive sense, and all these modifications will be included in its scope. Likewise, the advantages, other advantages, and solutions to problems of the various embodiments have been described above. However, benefits, advantages, solutions to problems, and any solutions that can produce these or make them more specific should not be construed as critical, necessary, or necessary. The term "including" and any other variants thereof used in this article are non-exclusive inclusions. Such a process, method, article or device that includes a list of elements not only includes these elements, but also includes those that are not explicitly listed or are not part of the process. , Methods, systems, articles or other elements of equipment. In addition, the term "coupled" and any other variations thereof used herein refer to physical connection, electrical connection, magnetic connection, optical connection, communication connection, functional connection and/or any other connection.
具有本领域技术的人将认识到,在不脱离本发明的基本原理的情况下,可以对上述实施例的细节进行许多改变。因此,本发明的范围应根据以下权利要求确定。Those skilled in the art will recognize that many changes can be made to the details of the above-described embodiments without departing from the basic principles of the present invention. Therefore, the scope of the present invention should be determined according to the following claims.

Claims (36)

  1. 一种子宫内膜蠕动的检测方法,其特征在于包括:A method for detecting endometrial peristalsis, which is characterized in that it comprises:
    向子宫内膜发射第一超声波,并接收所述第一超声波的回波,获得第一超声回波数据;Transmitting a first ultrasonic wave to the endometrium and receiving the echo of the first ultrasonic wave to obtain the first ultrasonic echo data;
    根据所述第一超声回波数据获得所述子宫内膜的超声图像;Obtaining an ultrasound image of the endometrium according to the first ultrasound echo data;
    根据所述超声图像确定感兴趣区域;Determining a region of interest according to the ultrasound image;
    向所述感兴趣区域对应的生物组织发射第二超声波,并接收所述第二超声波的回波,获得第二超声回波数据;Transmitting a second ultrasonic wave to the biological tissue corresponding to the region of interest, and receiving an echo of the second ultrasonic wave, to obtain second ultrasonic echo data;
    根据所述第二超声回波数据,确定所述感兴趣区域内的点在预设时长内的蠕动位移或蠕动速度;Determine the creep displacement or creep velocity of a point in the region of interest within a preset time period according to the second ultrasonic echo data;
    根据所述感兴趣区域内的点在预设时长内的所述蠕动位移或蠕动速度,计算子宫内膜的蠕动参数,其中所述蠕动参数用于描述所述子宫内膜蠕动的运动状态;Calculating the peristaltic parameters of the endometrium according to the peristaltic displacement or peristaltic velocity of points in the region of interest within a preset period of time, where the peristaltic parameters are used to describe the motion state of the endometrial peristalsis;
    显示所述蠕动参数。The peristaltic parameters are displayed.
  2. 如权利要求1所述的方法,其特征在于,根据所述超声图像确定感兴趣区域包括:The method of claim 1, wherein determining the region of interest according to the ultrasound image comprises:
    根据用户的输入确定感兴趣区域;或者,Determine the area of interest based on user input; or,
    对所述超声图像进行图像处理,得到子宫内膜的边界,将所述子宫内膜的边界所形成的区域作为感兴趣区域。Image processing is performed on the ultrasound image to obtain the boundary of the endometrium, and the area formed by the boundary of the endometrium is taken as a region of interest.
  3. 一种子宫内膜蠕动的检测方法,其特征在于包括:A method for detecting endometrial peristalsis, which is characterized in that it comprises:
    向子宫内膜发射超声波,并接收所述超声波的回波,获得超声回波数据;Transmit ultrasonic waves to the endometrium, receive echoes of the ultrasonic waves, and obtain ultrasonic echo data;
    根据所述超声回波数据获得所述子宫内膜的超声图像;Obtaining an ultrasound image of the endometrium according to the ultrasound echo data;
    根据所述超声回波数据,确定所述子宫内膜中的点在预设时长内的蠕动位移或蠕动速度;Determine the peristaltic displacement or peristaltic velocity of a point in the endometrium within a preset period of time according to the ultrasound echo data;
    根据所述子宫内膜中的点在所述预设时长内的所述蠕动位移或蠕动速度,计算所述子宫内膜的蠕动参数,其中所述蠕动参数用于描述所述子宫内膜蠕动的运动状态;According to the peristaltic displacement or peristaltic velocity of a point in the endometrium within the preset period of time, the peristaltic parameters of the endometrial lining are calculated, wherein the peristaltic parameters are used to describe the peristalsis of the endometrium Motion state
    显示所述蠕动参数。The peristaltic parameters are displayed.
  4. 一种子宫内膜蠕动的检测方法,其特征在于包括:A method for detecting endometrial peristalsis, which is characterized in that it comprises:
    获取子宫内膜的超声回波数据;Obtain ultrasound echo data of the endometrium;
    根据所述超声回波数据,确定所述子宫内膜中的点在预设时长内的蠕动位移或蠕动速度;Determine the peristaltic displacement or peristaltic velocity of a point in the endometrium within a preset period of time according to the ultrasound echo data;
    根据所述子宫内膜中的点在所述预设时长内的所述蠕动位移或蠕动速度,计算所述子宫内膜的蠕动参数,其中所述蠕动参数用于描述所述子宫内膜蠕动的运动状态;According to the peristaltic displacement or peristaltic velocity of a point in the endometrium within the preset period of time, the peristaltic parameters of the endometrial lining are calculated, wherein the peristaltic parameters are used to describe the peristalsis of the endometrium Motion state
    显示所述蠕动参数。The peristaltic parameters are displayed.
  5. 如权利要求1-4中任意一项所述的方法,其特征在于,所述蠕动参数包括蠕动的幅度、蠕动的频次、预设时长内的总显著蠕动运动时间、蠕动运动的传播方向、蠕动运动的传播速度、蠕动运动的范围、蠕动运动的紊乱程度、蠕动幅度的不均匀程度、蠕动方向的不均匀程度和子宫内膜中蠕动运动分布中的至少一种。The method according to any one of claims 1 to 4, wherein the peristaltic parameters include the amplitude of peristaltic movement, the frequency of peristaltic movement, the total significant peristaltic movement time within a preset period of time, the propagation direction of peristaltic movement, and the peristaltic movement. At least one of the propagation speed of the movement, the range of the peristaltic movement, the degree of disorder of the peristaltic movement, the degree of unevenness of the peristaltic amplitude, the degree of unevenness of the peristaltic direction, and the distribution of peristaltic movement in the endometrium.
  6. 如权利要求1-4中任意一项所述的方法,其特征在于,所述预设时长大于或等于蠕动的周期。The method according to any one of claims 1 to 4, wherein the preset duration is greater than or equal to the period of peristalsis.
  7. 如权利要求1-4中任意一项所述的方法,其特征在于,所述蠕动参数包括蠕动导致的组织应变、蠕动导致的组织应变率、蠕动运动的加速度中的至少一种。The method according to any one of claims 1 to 4, wherein the peristaltic parameters include at least one of tissue strain caused by peristaltic motion, tissue strain rate caused by peristaltic motion, and acceleration of peristaltic motion.
  8. 如权利要求1-4中任意一项所述的方法,其特征在于,所述蠕动参数包括所述蠕动位移或所述蠕动速度的至少一个统计量。The method according to any one of claims 1 to 4, wherein the peristaltic parameter includes at least one statistic of the peristaltic displacement or the peristaltic velocity.
  9. 如权利要求3或4所述的方法,其特征在于,根据所述超声回波数据,确定所述子宫内膜中的点在预设时长内的蠕动位移包括:The method according to claim 3 or 4, wherein, according to the ultrasound echo data, determining the peristaltic displacement of a point in the endometrium within a preset period of time comprises:
    从所述超声回波数据中检测所述子宫内膜中的点在不同时刻的超声回波数据段;Detecting ultrasonic echo data segments of points in the endometrium at different moments from the ultrasonic echo data;
    选取所述子宫内膜中的点在一时刻的超声回波数据段,在另一时刻的超声回波数据段中进行搜索,找出与选取点的超声回波数据段相关性最大的点,找出的点的位置为选取的点在另一时刻的位置,得到选取的点在这两个时刻下的蠕动位移;Select the point in the endometrium in the ultrasound echo data segment at one time, and search in the ultrasound echo data segment at the other time to find the point that has the greatest correlation with the ultrasound echo data segment of the selected point, The position of the found point is the position of the selected point at another moment, and the creep displacement of the selected point at these two moments is obtained;
    以此类推得到所述子宫内膜中的点在预设时长内不同时刻的蠕动位移。By analogy, the peristaltic displacements of the points in the endometrium at different times within the preset time period are obtained.
  10. 如权利要求3或4所述的方法,其特征在于,根据所述子宫内膜中的点在所述预设时长内的所述蠕动位移或蠕动速度,计算所述子宫内膜的蠕动参数包括:The method according to claim 3 or 4, wherein the calculation of the peristaltic parameters of the endometrium according to the peristaltic displacement or peristaltic velocity of a point in the endometrium within the preset time period comprises :
    根据所述子宫内膜中的点在所述预设时长内的所述蠕动位移或蠕动速度,生成蠕动位移与时间的关系曲线或蠕动速度与时间的关系曲线;According to the peristaltic displacement or peristaltic velocity of a point in the endometrium within the preset time period, generating a peristaltic displacement and time relationship curve or a peristaltic velocity and time relationship curve;
    根据所述关系曲线计算所述蠕动的幅度、频次、预设时长内的总显著运动时间中的至少一种。At least one of the amplitude, frequency, and total significant movement time within a preset duration of the peristalsis is calculated according to the relationship curve.
  11. 如权利要求3或4所述的方法,其特征在于,根据所述子宫内膜中的点在所述预设时长内的所述蠕动位移或蠕动速度,计算所述子宫内膜的蠕动参数包括:The method according to claim 3 or 4, wherein the calculation of the peristaltic parameters of the endometrium according to the peristaltic displacement or peristaltic velocity of a point in the endometrium within the preset time period comprises :
    根据所述子宫内膜中的点在所述预设时长内的所述蠕动位移或蠕动速度,计算得到所述子宫内膜中的点的运动参数;所述运动参数包括最大蠕动位移值、最小蠕动位移值、平均蠕动位移值、总显著运动时间中的至少一种;According to the peristaltic displacement or peristaltic velocity of the point in the endometrium within the preset time period, the motion parameter of the point in the endometrium is calculated; the motion parameter includes a maximum peristaltic displacement value and a minimum peristaltic displacement value. At least one of creeping displacement value, average creeping displacement value, and total significant movement time;
    根据所述子宫内膜中的点到达预设运动参数的先后顺序,得到蠕动的传播方向。According to the sequence of the points in the endometrium reaching the preset motion parameters, the propagation direction of the peristalsis is obtained.
  12. 如权利要求11所述的方法,其特征在于,得到蠕动的传播方向之后,还包括:The method according to claim 11, characterized in that, after obtaining the propagation direction of the peristalsis, the method further comprises:
    根据传播方向上的至少两点的间距以及这两点到达预设运动参数的时间差,得到蠕动的传播速度。According to the distance between at least two points in the propagation direction and the time difference between the two points reaching the preset motion parameters, the propagation speed of the peristalsis is obtained.
  13. 如权利要求11所述的方法,其特征在于,计算得到所述子宫内膜中的点的运动参数之后,还包括:The method according to claim 11, wherein after calculating the motion parameters of the points in the endometrium, the method further comprises:
    判断所述子宫内膜中的点的运动参数是否超过预设的参数阈值;Judging whether the motion parameter of the point in the endometrium exceeds a preset parameter threshold;
    将运动参数超过所述参数阈值的点形成的区域作为蠕动范围。The area formed by the points where the motion parameter exceeds the parameter threshold is taken as the peristaltic range.
  14.        如权利要求1-4中任意一项所述的方法,其特征在于,显示所述蠕动参数包括:显示所述蠕动参数与时间的关系曲线。The method according to any one of claims 1-4, wherein the displaying of the peristaltic parameters comprises: displaying a curve of the relationship between the peristaltic parameters and time.
  15. 一种生物组织蠕动的检测方法,其特征在于包括:A method for detecting peristalsis of biological tissues, which is characterized in that it comprises:
    获取蠕动对象的超声回波数据;Acquire ultrasonic echo data of a peristaltic object;
    根据所述超声回波数据,确定所述蠕动对象中的点在预设时长内的蠕动位移或蠕动速度;Determine the creep displacement or creep velocity of a point in the peristaltic object within a preset period of time according to the ultrasonic echo data;
    根据所述蠕动对象中的点在所述预设时长内的所述蠕动位移或蠕动速度,计算所述蠕动对象的蠕动参数,其中所述蠕动参数用于描述所述蠕动对象蠕动的运动状态;Calculating the peristaltic parameters of the peristaltic object according to the peristaltic displacement or peristaltic velocity of a point in the peristaltic object within the preset time period, where the peristaltic parameters are used to describe the peristaltic motion state of the peristaltic object;
    显示所述蠕动参数。The peristaltic parameters are displayed.
  16. 如权利要求15所述的方法,其特征在于,根据所述超声回波数据,确定所述蠕动对象中的点在预设时长内的蠕动位移包括:The method according to claim 15, wherein, according to the ultrasonic echo data, determining the peristaltic displacement of a point in the peristaltic object within a preset period of time comprises:
    从所述超声回波数据中检测所述蠕动对象中的点在不同时刻的超声回波数据段;Detecting ultrasonic echo data segments of points in the peristaltic object at different moments from the ultrasonic echo data;
    选取所述蠕动对象中的点在一时刻的超声回波数据段,在另一时刻的超声回波数据段中进行搜索,找出与选取点的超声回波数据段相关性最大的点,找出的点的位置为选取的点在另一时刻的位置,得到选取的点在这两个时刻下的蠕动位移;Select the point in the peristaltic object in the ultrasonic echo data segment at one time, and search in the ultrasonic echo data segment at another time to find the point with the greatest correlation with the ultrasonic echo data segment of the selected point, and find The position of the selected point is the position of the selected point at another moment, and the creep displacement of the selected point at these two moments is obtained;
    以此类推得到所述蠕动对象中的点在预设时长内不同时刻的蠕动位移。By analogy, the creep displacements of the points in the creeping object at different times within the preset time period are obtained.
  17.        如权利要求15所述的方法,其特征在于,根据所述蠕动对象中的点在所述预设时长内的所述蠕动位移或蠕动速度,计算所述蠕动对象的蠕动参数包括:The method of claim 15, wherein the calculation of the creep parameters of the creeping object according to the creeping displacement or creeping speed of a point in the creeping object within the preset time period comprises:
    根据所述蠕动对象中的点在所述预设时长内的所述蠕动位移或蠕动速度,生成蠕动位移与时间的关系曲线或蠕动速度与时间的关系曲线;According to the creep displacement or creep speed of a point in the creeping object within the preset time period, generating a creeping displacement versus time curve or creeping speed versus time curve;
    根据所述关系曲线计算所述蠕动的幅度、频次、预设时长内的总显著运动时间中的至少一种。At least one of the amplitude, frequency, and total significant movement time within a preset duration of the peristalsis is calculated according to the relationship curve.
  18. 一种子宫内膜蠕动的检测方法,其特征在于包括:A method for detecting endometrial peristalsis, which is characterized in that it comprises:
    向子宫内膜发射第一超声波,并接收所述第一超声波的回波,获得第一超声回波数据;Transmitting a first ultrasonic wave to the endometrium and receiving the echo of the first ultrasonic wave to obtain the first ultrasonic echo data;
    根据所述第一超声回波数据获得子宫内膜的超声图像;Obtaining an ultrasound image of the endometrium according to the first ultrasound echo data;
    根据所述超声图像确定感兴趣区域;Determining a region of interest according to the ultrasound image;
    向所述感兴趣区域对应的生物组织发射第二超声波,并接收所述第二超声波的回波,获得第二超声回波数据;Transmitting a second ultrasonic wave to the biological tissue corresponding to the region of interest, and receiving an echo of the second ultrasonic wave, to obtain second ultrasonic echo data;
    根据所述第二超声回波数据,确定所述感兴趣区域内的子宫内膜的蠕动位移或蠕动速度;Determining the peristaltic displacement or peristaltic velocity of the endometrium in the region of interest according to the second ultrasound echo data;
    显示所述蠕动位移或蠕动速度。Display the creeping displacement or creeping speed.
  19. 一种子宫内膜蠕动的检测方法,其特征在于包括:A method for detecting endometrial peristalsis, which is characterized in that it comprises:
    向子宫内膜发射超声波,并接收所述超声波的回波,获得超声回波数据;Transmit ultrasonic waves to the endometrium, receive echoes of the ultrasonic waves, and obtain ultrasonic echo data;
    根据所述超声回波数据获得所述子宫内膜的超声图像;Obtaining an ultrasound image of the endometrium according to the ultrasound echo data;
    根据所述超声回波数据,确定所述子宫内膜中的蠕动位移或蠕动速度;Determine the peristaltic displacement or peristaltic velocity in the endometrium according to the ultrasound echo data;
    显示所述蠕动位移或蠕动速度。Display the creeping displacement or creeping speed.
  20. 一种子宫内膜蠕动的检测方法,其特征在于包括:A method for detecting endometrial peristalsis, which is characterized in that it comprises:
    获取子宫内膜的超声回波数据;Obtain ultrasound echo data of the endometrium;
    根据所述超声回波数据,确定所述子宫内膜的蠕动位移或蠕动速度;Determine the peristaltic displacement or peristaltic velocity of the endometrium according to the ultrasound echo data;
    显示所述蠕动位移或蠕动速度。Display the creeping displacement or creeping speed.
  21. 一种生物组织蠕动的检测方法,其特征在于包括:A method for detecting peristalsis of biological tissues, which is characterized in that it comprises:
    向蠕动对象发射第一超声波,并接收所述第一超声波的回波,获得第一超声回波数据;Transmitting a first ultrasonic wave to the peristaltic object, and receiving the echo of the first ultrasonic wave, to obtain the first ultrasonic echo data;
    根据所述第一超声回波数据获得所述蠕动对象的超声图像;Obtaining an ultrasound image of the peristaltic object according to the first ultrasound echo data;
    根据所述超声图像确定感兴趣区域;Determining a region of interest according to the ultrasound image;
    向所述感兴趣区域对应的生物组织发射第二超声波,并接收所述第二超声波的回波,获得第二超声回波数据;Transmitting a second ultrasonic wave to the biological tissue corresponding to the region of interest, and receiving an echo of the second ultrasonic wave, to obtain second ultrasonic echo data;
    根据所述第二超声回波数据,确定所述感兴趣区域内的蠕动对象的蠕动位移或蠕动速度;Determining the creeping displacement or creeping velocity of the creeping object in the region of interest according to the second ultrasonic echo data;
    显示所述蠕动位移或蠕动速度。Display the creeping displacement or creeping speed.
  22. 一种生物组织蠕动的检测方法,其特征在于包括:A method for detecting peristalsis of biological tissues, which is characterized in that it comprises:
    向蠕动对象发射超声波,并接收所述超声波的回波,获得超声回波数据;Transmit ultrasonic waves to the peristaltic object, receive echoes of the ultrasonic waves, and obtain ultrasonic echo data;
    根据所述超声回波数据获得所述蠕动对象的超声图像;Obtaining an ultrasound image of the peristaltic object according to the ultrasound echo data;
    根据所述超声回波数据,确定所述蠕动对象的蠕动位移或蠕动速度;Determine the creeping displacement or creeping velocity of the creeping object according to the ultrasonic echo data;
    显示所述蠕动位移或蠕动速度。Display the creeping displacement or creeping speed.
  23.        如权利要求18至22中任意一项所述的方法,其特征在于,显示所述蠕动位移或蠕动速度包括:显示所述蠕动位移的大小、所述蠕动位移的方向、所述蠕动速度的大小和所述蠕动速度的方向中的至少一个。The method according to any one of claims 18 to 22, wherein displaying the creeping displacement or creeping speed comprises: displaying the size of the creeping displacement, the direction of the creeping displacement, and the size of the creeping speed And at least one of the directions of the creeping speed.
  24. 如权利要求18至22中任意一项所述的方法,其特征在于,显示所述蠕动位移或蠕动速度包括:显示所述蠕动位移或所述蠕动速度随时间变化的曲线图。The method according to any one of claims 18 to 22, wherein displaying the creeping displacement or the creeping speed comprises: displaying a graph of the creeping displacement or the creeping speed with time.
  25. 如权利要求18至22中任意一项所述的方法,其特征在于,显示所述蠕动位移或蠕动速度包括:The method according to any one of claims 18 to 22, wherein displaying the creeping displacement or creeping speed comprises:
    将所述蠕动位移或所述蠕动速度映射为不同的颜色,获得彩色映射图;Mapping the creeping displacement or the creeping speed to different colors to obtain a color mapping diagram;
    显示所述彩色映射图。The color map is displayed.
  26. 一种超声成像设备,其特征在于包括:An ultrasonic imaging equipment, which is characterized by comprising:
    超声探头,用于向生物组织内的感兴趣区域发射超声波,并接收所述超声波的回波;An ultrasound probe, which is used to transmit ultrasonic waves to a region of interest in biological tissues and receive echoes of the ultrasonic waves;
    发射/接收电路,用于控制超声探头向子宫内膜发射超声波,并接收所述超声波的回波,获得超声回波数据;The transmitting/receiving circuit is used to control the ultrasonic probe to transmit ultrasonic waves to the endometrium and receive the echo of the ultrasonic waves to obtain ultrasonic echo data;
    人机交互装置,用于接收用户的输入和输出可视化信息;Human-computer interaction device, used to receive user input and output visual information;
    处理器,用于根据所述超声回波数据获得所述子宫内膜的超声图像;根据所述超声回波数据,确定所述子宫内膜中的点在预设时长内的蠕动位移或蠕动速度;根据所述子宫内膜中的点在所述预设时长内的所述蠕动位移或蠕动速度,计算所述子宫内膜的蠕动参数,其中所述蠕动参数用于描述所述子宫内膜蠕动的运动状态;通过所述人机交互装置显示所述蠕动参数。A processor, configured to obtain an ultrasound image of the endometrium according to the ultrasound echo data; determine the peristaltic displacement or peristaltic velocity of a point in the endometrium within a preset time according to the ultrasound echo data Calculate the peristaltic parameters of the endometrium according to the peristaltic displacement or peristaltic velocity of a point in the endometrium within the preset time period, wherein the peristaltic parameters are used to describe the endometrial peristalsis The state of motion; the peristaltic parameters are displayed through the human-computer interaction device.
  27. 如权利要求26所述的超声成像设备,其特征在于,所述蠕动参数包括蠕动的幅度、频次、预设时长内的总显著运动时间、传播方向、传播速度、蠕动范围中的至少一种。The ultrasonic imaging device according to claim 26, wherein the peristaltic parameters include at least one of the amplitude, frequency, total significant movement time within a preset period of time, propagation direction, propagation velocity, and peristaltic range of the peristalsis.
  28.        如权利要求26所述的超声成像设备,其特征在于,所述预设时长大于或等于蠕动的周期。The ultrasonic imaging device according to claim 26, wherein the preset duration is greater than or equal to the period of peristalsis.
  29.        如权利要求26所述的超声成像设备,其特征在于,所述处理器根据所述超声回波数据,确定所述子宫内膜中的点在预设时长内的蠕动位移包括:The ultrasound imaging device according to claim 26, wherein the processor determining the peristaltic displacement of a point in the endometrium within a preset period of time according to the ultrasound echo data comprises:
    从所述超声回波数据中检测所述子宫内膜中的点在不同时刻的超声回波数据段;Detecting ultrasonic echo data segments of points in the endometrium at different moments from the ultrasonic echo data;
    选取所述子宫内膜中的点在一时刻的超声回波数据段,在另一时刻的超声回波数据段中进行搜索,找出与选取点的超声回波数据段相关性最大的点,找出的点的位置为选取的点在另一时刻的位置,得到选取的点在这两个时刻下的蠕动位移;Select the point in the endometrium in the ultrasound echo data segment at one time, and search in the ultrasound echo data segment at the other time to find the point that has the greatest correlation with the ultrasound echo data segment of the selected point, The position of the found point is the position of the selected point at another moment, and the creep displacement of the selected point at these two moments is obtained;
    以此类推得到所述子宫内膜中的点在预设时长内不同时刻的蠕动位移。By analogy, the peristaltic displacements of the points in the endometrium at different times within the preset time period are obtained.
  30. 如权利要求26所述的超声成像设备,其特征在于,所述处理器根据所述子宫内膜中的点在所述预设时长内的所述蠕动位移或蠕动速度,计算所述子宫内膜的蠕动参数包括:The ultrasonic imaging device according to claim 26, wherein the processor calculates the endometrial membrane based on the peristaltic displacement or the peristaltic velocity of a point in the endometrium within the preset time period. The peristaltic parameters include:
    根据所述子宫内膜中的点在所述预设时长内的所述蠕动位移或蠕动速度,生成蠕动位移与时间的关系曲线或蠕动速度与时间的关系曲线;According to the peristaltic displacement or peristaltic velocity of a point in the endometrium within the preset time period, generating a peristaltic displacement and time relationship curve or a peristaltic velocity and time relationship curve;
    根据所述关系曲线计算所述蠕动的幅度、频次、预设时长内的总显著运动时间中的至少一种。At least one of the amplitude, frequency, and total significant movement time within a preset duration of the creeping motion is calculated according to the relationship curve.
  31.        如权利要求26所述的超声成像设备,其特征在于,所述处理器根据所述子宫内膜中的点在所述预设时长内的所述蠕动位移或蠕动速度,计算所述子宫内膜的蠕动参数包括:The ultrasonic imaging device according to claim 26, wherein the processor calculates the endometrial membrane based on the peristaltic displacement or the peristaltic velocity of a point in the endometrium within the preset time period. The peristaltic parameters include:
    根据所述子宫内膜中的点在所述预设时长内的所述蠕动位移或蠕动速度,计算得到所述子宫内膜中的点的运动参数;所述运动参数包括最大蠕动位移值、最小蠕动位移值、平均蠕动位移值、总显著运动时间中的至少一种;According to the peristaltic displacement or peristaltic velocity of the point in the endometrium within the preset time period, the motion parameter of the point in the endometrium is calculated; the motion parameter includes a maximum peristaltic displacement value and a minimum peristaltic displacement value. At least one of creeping displacement value, average creeping displacement value, and total significant movement time;
    根据所述子宫内膜中的点到达预设运动参数的先后顺序,得到蠕动的传播方向。According to the sequence of the points in the endometrium reaching the preset motion parameters, the propagation direction of the peristalsis is obtained.
  32. 如权利要求31所述的超声成像设备,其特征在于,所述处理器得到蠕动的传播方向之后,还用于:The ultrasonic imaging device according to claim 31, wherein after the processor obtains the propagation direction of the peristalsis, it is further used for:
    根据传播方向上的至少两点的间距以及这两点到达预设运动参数的时间差,得到蠕动的传播速度。According to the distance between at least two points in the propagation direction and the time difference between the two points reaching the preset motion parameters, the propagation speed of the peristalsis is obtained.
  33. 如权利要求31所述的超声成像设备,其特征在于,所述处理器计算得到所述子宫内膜中的点的运动参数之后,还用于:The ultrasound imaging device according to claim 31, wherein after the processor calculates the motion parameters of the points in the endometrium, it is further used for:
    判断所述子宫内膜中的点的运动参数是否超过预设的参数阈值;Judging whether the motion parameter of the point in the endometrium exceeds a preset parameter threshold;
    将运动参数超过所述参数阈值的点形成的区域作为蠕动范围。The area formed by the points where the motion parameter exceeds the parameter threshold is taken as the peristaltic range.
  34. 如权利要求26所述的超声成像设备,其特征在于,所述处理器通过所述人机交互装置显示所述蠕动参数包括:The ultrasound imaging device of claim 26, wherein the processor displaying the peristaltic parameters through the human-computer interaction device comprises:
    通过所述人机交互装置显示所述蠕动参数与时间的关系曲线。The relationship curve between the peristaltic parameters and time is displayed by the human-computer interaction device.
  35.        一种超声成像设备,其特征在于包括:An ultrasonic imaging device, which is characterized by including:
    存储器,用于存储程序;Memory, used to store programs;
    处理器,用于执行所述存储器存储的程序以实现如权利要求1-25中任一项所述的方法。The processor is configured to execute the program stored in the memory to implement the method according to any one of claims 1-25.
  36. 一种计算机可读存储介质,其特征在于,包括程序,所述程序能够被处理器执行以实现如权利要求1-25中任一项所述的方法。A computer-readable storage medium, characterized by comprising a program, which can be executed by a processor to implement the method according to any one of claims 1-25.
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