WO2021045311A1 - Appareil d'inhibition du rétrécissement de l'urètre - Google Patents

Appareil d'inhibition du rétrécissement de l'urètre Download PDF

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Publication number
WO2021045311A1
WO2021045311A1 PCT/KR2019/014897 KR2019014897W WO2021045311A1 WO 2021045311 A1 WO2021045311 A1 WO 2021045311A1 KR 2019014897 W KR2019014897 W KR 2019014897W WO 2021045311 A1 WO2021045311 A1 WO 2021045311A1
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WO
WIPO (PCT)
Prior art keywords
catheter
drug
urethra
urethral stricture
suppression device
Prior art date
Application number
PCT/KR2019/014897
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English (en)
Korean (ko)
Inventor
박명찬
Original Assignee
인제대학교 산학협력단
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Publication of WO2021045311A1 publication Critical patent/WO2021045311A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0017—Catheters; Hollow probes specially adapted for long-term hygiene care, e.g. urethral or indwelling catheters to prevent infections
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A61M25/0026—Multi-lumen catheters with stationary elements
    • A61M25/0029—Multi-lumen catheters with stationary elements characterized by features relating to least one lumen located at the middle part of the catheter, e.g. slots, flaps, valves, cuffs, apertures, notches, grooves or rapid exchange ports
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0041—Catheters; Hollow probes characterised by the form of the tubing pre-formed, e.g. specially adapted to fit with the anatomy of body channels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/02—Holding devices, e.g. on the body
    • A61M25/04—Holding devices, e.g. on the body in the body, e.g. expansible
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M25/1018—Balloon inflating or inflation-control devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A61M25/0026—Multi-lumen catheters with stationary elements
    • A61M2025/004—Multi-lumen catheters with stationary elements characterized by lumina being arranged circumferentially
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/10—Trunk
    • A61M2210/1078—Urinary tract
    • A61M2210/1089—Urethra

Definitions

  • the present invention relates to a device for inhibiting urethral stenosis, and more particularly, as a device for applying and maintaining insertion into the urethra to prevent re-stenosis at the site after surgery for urethral stenosis, and an anti-adhesion agent at the surgical site or the urethral stricture site
  • the present invention relates to a device for inhibiting urethral stricture that allows the injection of the anti-adhesion agent to be easily administered and applied, prevents diffusion and loss of the administered anti-adhesion agent, and firmly maintains a state inserted into the urethra.
  • a catheter refers to a tube formed in a longitudinal direction that is inserted through the patient's urethra to the bladder in order to collect the patient's urine into a urine bag. It consists of an air pipe that prevents it.
  • the'double balloon-type catheter' disclosed in Republic of Korea Utility Model No. 269507 (hereinafter referred to as Document 1), it is made of a soft material such as rubber or silicone, so that one end is closed, and the other end is closed.
  • the inflation tube closes the urethral connection part of the bladder in the patient's bladder. It consists of a configuration in which the urethra of the patient is double-closed as the auxiliary inflator tube closes the urethra.
  • the terminal A discharge opening and an injection opening disposed in the inlet; An inlet port disposed at a base end for injecting an injection fluid; An outlet port disposed at the base end for discharging fluid from the intestine; A discharge passage connecting the discharge opening and the discharge port; An injection passage connecting the inlet port and the injection opening; A valve disposed adjacent to the discharge opening at the distal end, which closes the discharge flow path against fluid entry from the intestine; A valve control port disposed at the base end to draw in the control fluid under pressure; And a control flow path connecting the valve control port and the valve so that the valve closes the discharge flow path in response to the control fluid introduced under pressure, wherein the flow of the control fluid to the valve is unidirectional, and the valve is pressure It remains closed after the control fluid enters the
  • the present invention was created to solve the problems of the prior art as described above, as a device for applying and maintaining insertion into the urethra in order to prevent reconstriction at the site after surgery for urethral stenosis.
  • the purpose is to provide a device for suppressing urethral stenosis that allows the anti-adhesion agent to be easily administered and applied, prevents the administered anti-adhesion agent from spreading to unnecessary areas, and keeps the inserted state firmly in the urethra. Are left.
  • the present invention for achieving the above object is a catheter 11;
  • Departure prevention means 12 for preventing separation of the catheter 11 and maintaining airtightness of the bladder 2 by providing a locking portion through expansion in the urination port 2a portion of the bladder 2;
  • a drug delivery means (13) provided in a portion of the catheter (11) where the surgical site or the constriction area (3) is located to administer a therapeutic drug; It is provided in a portion of the catheter 11 where the outer tip portion 1a of the urethra is located, and blocks the flow of the therapeutic agent administered through the drug delivery means 13 to the outer tip portion 1a of the urethra due to internal pressure and outflow,
  • An airtight fixing holding means (14) for preventing flow by providing a pressure fixing force between the separation preventing means (12) and the outer front end (1a) of the urethra;
  • a drug diffusion prevention means (15) that forms annular protrusions at both ends of the drug delivery means (13) at both ends of the drug delivery means (13) to prevent the administered
  • Fixed position adjusting means (16) provided at the outer diameter of one end of the catheter (11) to adjust the position at which the airtight fixing means (14) is fixed in correspondence with the length of the wearer's urethra; It characterized in that it comprises a.
  • the present invention according to the problem solving means as described above is to administer an anti-adhesion agent, a therapeutic agent, to the surgical site or the urethral stricture site in order to insert and maintain the urethra in order to prevent the urethral stenosis from being re-stricted at the site after the operation.
  • an anti-adhesion agent a therapeutic agent
  • it has a structure that prevents the spread of the therapeutic drug to be administered and applied out of the treatment area to other urethral areas, thereby preventing unnecessary waste of expensive therapeutic drugs.
  • it has the effect of being administered periodically, continuously, and stably.
  • the present invention is provided with a drug delivery means 13 at a portion of the catheter 11 where the constricted portion 3 of the urethra is located, so that the therapeutic agent can be administered from the outside, so that the catheter 11
  • a drug delivery means 13 By expanding the stricture area (3) of the urethra, it prevents stenosis or adhesion, and at the same time obtains the effect of allowing rapid treatment while administering a therapeutic agent to the constricted area (3).
  • the present invention is by independently providing the drug delivery means (13) to be fitted in the form of a tube on the outer surface of the catheter (11), the urine discharge path (11c) and the fluid path (12b) and the drug
  • the drug delivery means (13) is by independently providing the drug delivery means (13) to be fitted in the form of a tube on the outer surface of the catheter (11), the urine discharge path (11c) and the fluid path (12b) and the drug
  • the present invention as described above, by independently providing a tube (13d) constituting the drug delivery means (13) to be fitted in the form of a tube on the outer surface of the catheter (11), according to the urethral constriction portion ( 13) can be adjusted, and through this, it has the effect of allowing the treatment to be performed by responding to the exact urethral stricture area.
  • the present invention is applied through the micropores (13c) by placing the drug diffusion preventing means (15) at both ends of the micropores (13c) of the drug delivery means (13) of the catheter (11) are arranged. It prevents the diffusion and outflow of the drug to other parts of the urethral stricture treatment area due to internal pressure, and through this, an effect of preventing unnecessary loss of expensive treatment drugs is obtained.
  • the present invention is formed by protruding the drug diffusion means 15 in the same body at both ends of the tube (13d) constituting the drug delivery means 13, by forming a space that can stay for a long time when the therapeutic drug is injected, The therapeutic drug is made to act evenly and uniformly over the entire constriction area (3) for a long time, and through this, the effect of maximizing the treatment is obtained.
  • the present invention is provided by inserting the airtight fixing means 14, which is an elastic ring, to a portion of the outer surface of the catheter 11 where the outer tip 1a of the urethra is located, so that the balloon 12c expanded in the bladder 2 ) And the urinary urethra outer tip portion 1a to provide a pressure fixing force to prevent the catheter 11 from flowing.
  • the airtight fixing means 14 which is an elastic ring
  • the present invention is a multi-stage position adjustment fixed position adjustment means 16 for varying the position according to the length of the urethra and maintaining the variable position on the surface of the catheter 11 in which the airtight fixing unit 14 is fitted.
  • FIG. 1 is a perspective view showing a configuration according to an embodiment of the present invention.
  • Figure 2 is a partial cross-sectional view showing the configuration of the catheter and drug administration means according to an embodiment of the present invention.
  • Figure 3 is a partial cross-sectional view showing the configuration of a catheter and drug delivery means according to another embodiment of the present invention.
  • Figure 4 is a partial cross-sectional perspective view showing the configuration of the airtight fixing holding means according to embodiments of the present invention.
  • Figure 5 is a side view of a part of the human body showing a urethral constriction state.
  • FIG. 6 is a side view of a human body part showing an example in which the present invention works by being inserted into a urethral constriction area.
  • the catheter 11 may be a tube body, in which a urine inlet hole 11a is provided at one end and a urine outlet 11b is provided at the other end.
  • the separation preventing means 12 includes a fluid path 12b extending along the catheter 11 from the connector 1 12a branched from the other end of the catheter 11; Includes; an annular balloon 12c provided at a portion of the outer surface of the catheter 11 where the bladder urination port 2a is located and communicated with the fluid path 12b to expand or contract according to the inflow or outflow of the fluid; It can be.
  • the separation preventing means 12 may be that the fluid path 12b extends from the connector 1 (12a) through the inside of the cross-section of the catheter 11 and communicates with an annular balloon 12c provided outside the catheter 11.
  • the separation preventing means 12 is a tube body that is separately fitted to the outer surface of the catheter 11, and a connector 1 (12a) provided at one end and an annular balloon 12c provided at the other end are provided in the fluid path (12b). It may be an entity that is communicated through.
  • the drug administration means 13 is a drug extended along the catheter 13 from the connector 2 (13a) branched from the other end of the catheter 11, as shown in FIG. Route of administration (13b); Micropores (13c) provided outside the catheter (11) where the constricted portion (3) of the urethra is located and communicated with the drug administration path (13b) to allow the drug to flow out to the constricted portion (3) of the urethra; It may be to include.
  • the drug administration means 13 is a plurality of drug administration paths (13b) extending from the connector 2 (13a) through the inside of the cross section of the catheter 11 (separate from the urine discharge path of the catheter) to be provided along the outer circumferential surface of the catheter 11 It may be in communication with the micropores 13c.
  • the drug administration means 13 is a drug administration path (13b) provided with a connector 2 (13a) at one end separately fixed in the form of a tube to the outside of the catheter 11, as shown in the accompanying drawings Figure 3;
  • the drug administration path (13b) may be fixed by being inserted into the fixing groove (13e) formed on the outer surface of the catheter 11 or the separation preventing means (12).
  • the airtight fixing means 14 may be an annular tube or a ring having elasticity that is connected to a separate fluid path and expands according to the inflow of fluid to block the outer tip 1a of the urethra.
  • the airtight fixing means 14 may be independent of the catheter 11 or the drug delivery means 13 so that the position is adjusted according to the position of the outer tip portion 1a of the urethra.
  • the drug diffusion preventing means 15 may be a pair of elastic rings fitted to both sides of the outer diameter of the catheter 11 in which the micropores 13c of the drug delivery means 13 are formed and fixed in close contact (Fig. 2).
  • the drug diffusion preventing means 15 may be a hwanjak protruding in the same body at both ends of the tube 13d constituting the drug delivery means 13 (see Fig. 3).
  • the fixed position adjusting means 16 is formed so that the fixed position of the airtight fixing means 14 is changed, but maintains the changed position, as shown in FIG. 4 of the accompanying drawings. It may be made of multi-stage irregularities.
  • the present invention is a catheter 11;
  • Departure prevention means 12 for preventing separation of the catheter 11 and maintaining airtightness of the bladder 2 by providing a locking portion through expansion in the urination port 2a portion of the bladder 2;
  • a drug delivery means (13) provided in a portion of the catheter (11) where the surgical site or the constriction area (3) is located to administer a therapeutic drug; It is provided in a portion of the catheter 11 where the outer tip portion 1a of the urethra is located, and blocks the flow of the therapeutic agent administered through the drug delivery means 13 to the outer tip portion 1a of the urethra due to internal pressure and outflow,
  • An airtight fixing holding means (14) for preventing flow by providing a pressure fixing force between the separation preventing means (12) and the outer front end (1a) of the urethra;
  • a drug diffusion prevention means (15) that forms annular protrusions at both ends of the drug delivery means (13) at both ends of the drug delivery means (13) to prevent the administered therapeutic drug from flowing and spreading
  • Fixed position adjusting means (16) provided at the outer diameter of one end of the catheter (11) to adjust the position at which the airtight fixing means (14) is fixed in correspondence with the length of the wearer's urethra; It is a urethral stricture suppression device 10 comprising a.
  • the present invention as described above has a structure capable of administering and applying an anti-adhesion agent to the surgical site or the urethral stricture site in order to prevent the urethral stenosis from being re-stricted in the area after surgery. , It is possible for anyone to easily administer the anti-adhesion agent periodically, continuously and stably.
  • the catheter 11 has a urine inlet hole 11a at one end, a urine outlet 11b is provided at the other end, and a flexible (for example, silicone) communicated through the urine outflow path 11c.
  • Material is a tube body, the urine inlet hole (11a) is provided on the side of one end blocked in a hemispherical shape, and the urine outlet (11b) provides a urine storage means (not shown; urine storage bag) and a connection part. do.
  • the catheter 11 is inserted into the bladder 2 through the urethra 1, and expands the constricted area 3 of the urethra 1 to suppress restenosis while allowing urine in the bladder to be discharged.
  • the separation preventing means 12 includes a fluid path 12b extending along the catheter 11 from the connector 1 12a branched from the other end of the catheter 11; Includes; an annular balloon 12c provided at a portion of the outer surface of the catheter 11 where the bladder urination port 2a is located and communicated with the fluid path 12b to expand or contract according to the inflow or outflow of the fluid; It is to do.
  • the annular balloon (12c) expands and is caught in the urination port (2a) of the bladder (2) to prevent separation. While maintaining the airtightness of the bladder (2).
  • the separation prevention means 12 is an annular balloon provided outside the catheter 11 by extending the fluid path 12b from the connector 1 (12a) through the inside of the cross section of the catheter 11 (separate from the urine discharge path of the catheter 11). It was connected with (12c).
  • the separation preventing means 12 is a tube body that is separately fitted to the outer surface of the catheter 11, and a connector 1 (12a) provided at one end and an annular balloon 12c provided at the other end are provided in the fluid path (12b). It is also desirable to communicate through.
  • the drug administration means 13 includes a drug administration path 13b extending along the catheter 13 from the connector 2 13a branched from the other end of the catheter 11; Micropores (13c) provided outside the catheter (11) where the constricted portion (3) of the urethra is located and communicated with the drug administration path (13b) to allow the drug to flow out to the constricted portion (3) of the urethra;
  • the drug administration means 13 is the drug administration path 13b extends from the connector 2 (13a) through the inside of the cross section of the catheter 11 (separate from the urine discharge path of the catheter) to the outer circumferential surface of the catheter 11 It is in communication with a plurality of micropores (13c) provided along the (see Fig. 2).
  • the present invention is provided with a drug delivery means 13 in a portion of the catheter 11 where the constricted portion 3 of the urethra is located, so that the therapeutic agent can be administered from the outside, so that the catheter 11 It is possible to prevent constriction or adhesion by expanding the constriction area (3) of the constriction area (3) and to allow rapid treatment while administering a therapeutic agent to the constriction area (3).
  • the drug administration means 13 is a drug administration path (13b) provided with a connector 2 (13a) at one end separately fixed in the form of a tube to the outside of the catheter 11, as shown in the accompanying drawings Figure 3;
  • the drug administration path (13b) is preferably fixed by being fitted into a fixing groove (13e) formed on the outer surface of the catheter 11 or separation preventing means (12).
  • the present invention comprises a separation preventing means 12 fitted in a tube shape on the outer surface of the catheter 11 and the catheter 11 and a drug delivery means 13 fitted in a tube shape on the outer surface of the catheter 11
  • a plurality of paths including a urine discharge path 11c, a fluid path 12b, and a drug administration path 13 in the catheter 11 by configuring the urethral stricture suppression device 10 by being inserted sequentially in each independently prepared state
  • the airtight fixing means 14 is an annular tube or a ring having elasticity that is connected to a separate fluid path and expands according to the inflow of fluid to block the outer tip 1a of the urethra.
  • the holding means 14 is independent of the catheter 11 or the drug delivery means 13 so that the position is adjusted according to the position of the outer tip of the urethra (1a), and the airtight fixing means 14 is the outer tip of the urethra (1a). The position is adjusted according to the position.
  • the present invention expands in response to the inflow of fluid through a fluid path separate from the urine outflow path at the portion where the outer end portion 1a of the urethra is located among the outer surface of the urethra 11 and expands the outer tip portion 1a of the urethra.
  • An airtight fixing holding means 14 made of either a blocking annular tube or an elastic ring is inserted, thereby preventing the outflow of the therapeutic agent administered through the drug delivery means 13 to the outside of the urethra due to internal pressure.
  • the present invention is by placing the drug diffusion preventing means (15) at both ends of the portion of the catheter 11 in which the micropores (13c) of the drug delivery means (13) are arranged, through the micropores (13c) It is possible to prevent unnecessary loss of expensive treatment drugs by preventing the spread of the applied drugs to parts other than the urethral stricture treatment area due to internal pressure.
  • the present invention is formed by protruding the drug diffusion means 15 in the same body at both ends of the tube (13d) constituting the drug delivery means 13, by forming a space that can stay for a long time when the therapeutic drug is injected, It is possible to maximize treatment by allowing the therapeutic drug to act evenly and uniformly over the entire constriction area (3) for a long time, and through this.
  • the fixed position adjusting means 16 is formed so that the fixed position of the airtight fixing means 14 is changed, but maintains the changed position, as shown in FIG. 4 of the accompanying drawings. It is made of multi-stage irregularities.
  • the present invention is a multi-stage position adjustment fixed position adjustment means 16 for varying the position according to the length of the urethra and maintaining the variable position on the surface of the catheter 11 in which the airtight fixing unit 14 is inserted.
  • the present invention is a multi-stage position adjustment fixed position adjustment means 16 for varying the position according to the length of the urethra and maintaining the variable position on the surface of the catheter 11 in which the airtight fixing unit 14 is inserted.
  • the present invention in order to prevent the stenosis from occurring again in the area after surgery for urethral stenosis, or to administer and apply an anti-adhesion agent in the state where the urethral stenosis is expanded,
  • the urethra (1), the constriction suppressing device (10), that is, the catheter 11 is inserted into the distal end of the catheter (11) to reach the bladder (2).
  • the catheter 11 Since the balloon (12c) inflated as described above is caught in the urinary opening (2a) part of the bladder (2), the catheter 11 is prevented from escaping from the bladder (2), and eventually the catheter 11 becomes the urethra ( 1) It prevents deviating from or flowing.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

La présente invention concerne un appareil d'inhibition du rétrécissement de l'urètre, et plus spécifiquement, un appareil d'inhibition du rétrécissement de l'urètre qui est appliqué et maintenu par insertion dans l'urètre afin d'empêcher un rétrécissement de revenir sur un site sur lequel une chirurgie du rétrécissement de l'urètre a été réalisée. L'appareil d'inhibition du rétrécissement de l'urètre permet à une barrière anti-adhérences d'être facilement administrée et appliquée à un site chirurgical ou à un site de rétrécissement de l'urètre, permet d'empêcher la barrière anti-adhérences administrée de s'étendre sur un site non nécessaire et d'être perdue, et permet de maintenir fermement l'état inséré de l'appareil dans l'urètre.
PCT/KR2019/014897 2019-09-03 2019-11-05 Appareil d'inhibition du rétrécissement de l'urètre WO2021045311A1 (fr)

Applications Claiming Priority (2)

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KR10-2019-0109044 2019-09-03
KR1020190109044A KR102281386B1 (ko) 2019-09-03 2019-09-03 요도 협착 억제장치

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KR102390728B1 (ko) * 2022-02-16 2022-04-25 안향남 약액 주입형 배뇨 카테터

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KR20030081323A (ko) * 2000-10-23 2003-10-17 에디컨인코포레이티드 여성의 요실금 치료를 위한 슬링-긴장도 측정 및 평가장치 및 방법
KR101538748B1 (ko) * 2007-12-11 2015-07-22 메사추세츠 인스티튜트 오브 테크놀로지 이식형 의약 투여 장치와 방광과 기타 신체 낭 또는 내강의 치료 방법
KR20150042917A (ko) * 2013-10-14 2015-04-22 주식회사 에이알씨코리아 요도협착을 방지하는 도뇨관
KR101837303B1 (ko) * 2016-11-14 2018-03-09 최돈경 도뇨장치

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