WO2021038487A3 - Compounds useful to treat pain - Google Patents

Compounds useful to treat pain Download PDF

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Publication number
WO2021038487A3
WO2021038487A3 PCT/IB2020/058010 IB2020058010W WO2021038487A3 WO 2021038487 A3 WO2021038487 A3 WO 2021038487A3 IB 2020058010 W IB2020058010 W IB 2020058010W WO 2021038487 A3 WO2021038487 A3 WO 2021038487A3
Authority
WO
WIPO (PCT)
Prior art keywords
compounds useful
present
relates
pharmaceutical composition
pain
Prior art date
Application number
PCT/IB2020/058010
Other languages
French (fr)
Other versions
WO2021038487A2 (en
Inventor
Pathik Subhashchandra BRAHMKSHATRIYA
Vishal Bharatbhai UNADKAT
Vishalgiri Gunvantgiri GOSWAMI
Heta Nishil PANDYA
Sandip Pareshbhai MEHTA
Original Assignee
Kashiv Biosciences, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kashiv Biosciences, Llc filed Critical Kashiv Biosciences, Llc
Priority to JP2022513091A priority Critical patent/JP2022546036A/en
Priority to AU2020337084A priority patent/AU2020337084A1/en
Priority to US17/638,332 priority patent/US20220288093A1/en
Priority to CA3152497A priority patent/CA3152497A1/en
Priority to EP20858967.1A priority patent/EP4021446A4/en
Priority to CN202080075238.4A priority patent/CN114727997A/en
Publication of WO2021038487A2 publication Critical patent/WO2021038487A2/en
Publication of WO2021038487A3 publication Critical patent/WO2021038487A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/655—Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

The present invention relates to compounds useful as bradykinin receptor antagonist, pharmaceutical composition comprising such compounds, and therapeutic use of the same. The present invention further relates to the combination of compounds useful for the therapeutic use. The present invention relates to the pharmaceutical composition comprising the compound and combination of compounds useful for treatment of urinary bladder pain, the symptomatic relief of pain, burning, urgency, frequency, and other discomforts arising from irritation of the lower urinary tract mucosa caused by infection, trauma, surgery, endoscopic procedures, or the passage of sounds or catheters.
PCT/IB2020/058010 2019-08-27 2020-08-27 Compounds useful to treat pain WO2021038487A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP2022513091A JP2022546036A (en) 2019-08-27 2020-08-27 Compounds Useful for Pain Treatment
AU2020337084A AU2020337084A1 (en) 2019-08-27 2020-08-27 Compounds useful to treat pain
US17/638,332 US20220288093A1 (en) 2019-08-27 2020-08-27 Compounds useful to treat pain
CA3152497A CA3152497A1 (en) 2019-08-27 2020-08-27 Compounds useful to treat pain
EP20858967.1A EP4021446A4 (en) 2019-08-27 2020-08-27 Compounds useful to treat pain
CN202080075238.4A CN114727997A (en) 2019-08-27 2020-08-27 Compounds for the treatment of pain

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN201921034555 2019-08-27
IN201921034555 2019-08-27

Publications (2)

Publication Number Publication Date
WO2021038487A2 WO2021038487A2 (en) 2021-03-04
WO2021038487A3 true WO2021038487A3 (en) 2021-05-14

Family

ID=74685258

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2020/058010 WO2021038487A2 (en) 2019-08-27 2020-08-27 Compounds useful to treat pain

Country Status (7)

Country Link
US (1) US20220288093A1 (en)
EP (1) EP4021446A4 (en)
JP (1) JP2022546036A (en)
CN (1) CN114727997A (en)
AU (1) AU2020337084A1 (en)
CA (1) CA3152497A1 (en)
WO (1) WO2021038487A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024508804A (en) * 2021-02-24 2024-02-28 カシーヴ バイオサイエンシズ，リミテッド・ライアビリティ・カンパニー Prodrugs of azo compounds and their salts

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040214753A1 (en) * 2003-03-20 2004-10-28 Britten Nancy Jean Dispersible pharmaceutical composition for treatment of mastitis and otic disorders
US20060264912A1 (en) * 2005-05-09 2006-11-23 Mcintyre Jon T Medical devices for treating urological and uterine conditions
US20070208134A1 (en) * 2005-10-03 2007-09-06 Hunter William L Anti-scarring drug combinations and use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008157205A2 (en) * 2007-06-15 2008-12-24 Duke University Methods and compositions for treating urinary tract infections using agents that mimic or elevate cyclic amp
CN108635335A (en) * 2018-06-13 2018-10-12 刘兆平 A kind of phenazopyridine hydrochloride capsule and preparation process

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040214753A1 (en) * 2003-03-20 2004-10-28 Britten Nancy Jean Dispersible pharmaceutical composition for treatment of mastitis and otic disorders
US20060264912A1 (en) * 2005-05-09 2006-11-23 Mcintyre Jon T Medical devices for treating urological and uterine conditions
US20070208134A1 (en) * 2005-10-03 2007-09-06 Hunter William L Anti-scarring drug combinations and use thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
AIZAWA ET AL.: "Effects of Phenazopyridine on Rat Bladder Primary Afferent Activity, and Comparison with Lidocaine and Acetaminophen", NEUROUROLOGY AND URODYNAMICS, vol. 29, 2010, pages 1445 - 1450, XP055822400 *
THOMAS ET AL.: "Excretion of Phenazopyridine and Its Metabolites in the Urine of Humans, Rats, Mice, and Guinea Pigs", JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 79, April 1990 (1990-04-01), pages 321 - 325, XP055904815 *

Also Published As

Publication number Publication date
JP2022546036A (en) 2022-11-02
AU2020337084A1 (en) 2022-04-07
EP4021446A2 (en) 2022-07-06
US20220288093A1 (en) 2022-09-15
CA3152497A1 (en) 2021-03-04
EP4021446A4 (en) 2023-09-13
WO2021038487A2 (en) 2021-03-04
CN114727997A (en) 2022-07-08

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