WO2020125119A1 - 一种水性胶囊及其制备方法 - Google Patents

一种水性胶囊及其制备方法 Download PDF

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Publication number
WO2020125119A1
WO2020125119A1 PCT/CN2019/107791 CN2019107791W WO2020125119A1 WO 2020125119 A1 WO2020125119 A1 WO 2020125119A1 CN 2019107791 W CN2019107791 W CN 2019107791W WO 2020125119 A1 WO2020125119 A1 WO 2020125119A1
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WIPO (PCT)
Prior art keywords
water
liquid
capsule
soluble
wall material
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PCT/CN2019/107791
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English (en)
French (fr)
Inventor
雷连龙
杨涛
杨紫刚
黄亮
洪学晖
Original Assignee
云南巴菰生物科技有限公司
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Priority to KR1020217023214A priority Critical patent/KR20220006032A/ko
Publication of WO2020125119A1 publication Critical patent/WO2020125119A1/zh

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    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/281—Treatment of tobacco products or tobacco substitutes by chemical substances the action of the chemical substances being delayed
    • A24B15/283—Treatment of tobacco products or tobacco substitutes by chemical substances the action of the chemical substances being delayed by encapsulation of the chemical substances
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
    • A24B15/302—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances by natural substances obtained from animals or plants
    • A24B15/303—Plant extracts other than tobacco
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES FOR CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
    • A24D3/00—Tobacco smoke filters, e.g. filter-tips, filtering inserts; Filters specially adapted for simulated smoking devices; Mouthpieces for cigars or cigarettes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00—Processes of polymerisation
    • C08F2/46—Polymerisation initiated by wave energy or particle radiation
    • C08F2/48—Polymerisation initiated by wave energy or particle radiation by ultraviolet or visible light
    • C08F2/50—Polymerisation initiated by wave energy or particle radiation by ultraviolet or visible light with sensitising agents
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F283/00—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G
    • C08F283/10—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G on to polymers containing more than one epoxy radical per molecule
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
    • C08F290/02—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated end groups
    • C08F290/06—Polymers provided for in subclass C08G
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES FOR CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
    • A24D3/00—Tobacco smoke filters, e.g. filter-tips, filtering inserts; Filters specially adapted for simulated smoking devices; Mouthpieces for cigars or cigarettes
    • A24D3/02—Manufacture of tobacco smoke filters
    • A24D3/0204—Preliminary operations before the filter rod forming process, e.g. crimping, blooming
    • A24D3/0212—Applying additives to filter materials
    • A24D3/0216—Applying additives to filter materials the additive being in the form of capsules, beads or the like
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES FOR CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
    • A24D3/00—Tobacco smoke filters, e.g. filter-tips, filtering inserts; Filters specially adapted for simulated smoking devices; Mouthpieces for cigars or cigarettes
    • A24D3/04—Tobacco smoke filters characterised by their shape or structure
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES FOR CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
    • A24D3/00—Tobacco smoke filters, e.g. filter-tips, filtering inserts; Filters specially adapted for simulated smoking devices; Mouthpieces for cigars or cigarettes
    • A24D3/04—Tobacco smoke filters characterised by their shape or structure
    • A24D3/048—Tobacco smoke filters characterised by their shape or structure containing additives
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES FOR CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
    • A24D3/00—Tobacco smoke filters, e.g. filter-tips, filtering inserts; Filters specially adapted for simulated smoking devices; Mouthpieces for cigars or cigarettes
    • A24D3/06—Use of materials for tobacco smoke filters
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES FOR CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
    • A24D3/00—Tobacco smoke filters, e.g. filter-tips, filtering inserts; Filters specially adapted for simulated smoking devices; Mouthpieces for cigars or cigarettes
    • A24D3/06—Use of materials for tobacco smoke filters
    • A24D3/061—Use of materials for tobacco smoke filters containing additives entrapped within capsules, sponge-like material or the like, for further release upon smoking
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES FOR CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
    • A24D3/00—Tobacco smoke filters, e.g. filter-tips, filtering inserts; Filters specially adapted for simulated smoking devices; Mouthpieces for cigars or cigarettes
    • A24D3/06—Use of materials for tobacco smoke filters
    • A24D3/067—Use of materials for tobacco smoke filters characterised by functional properties

Definitions

  • the invention belongs to the technical field of cigarette cigarette processing. More specifically, the present invention relates to an aqueous capsule, and also relates to a method for preparing the aqueous capsule.
  • the capsule has a wide range of uses, and the capsule shell has a barrier function, which can prevent the contents of the core from contacting the external environment of the capsule, and can also function as a tool for releasing the contents of the core at a desired release rate.
  • Capsules were first used in the field of medicine and health.
  • the medicines in medical capsules are generally powders or granules that are irritating to the esophagus and gastric mucosa, or have a bad taste, are easily volatile, are easily decomposed by saliva in the mouth, and are easily inhaled into the trachea. Medicine. These medicines are packed into capsules, which not only protect the medicine from being destroyed, but also protect the digestive organs and respiratory tract.
  • capsules Removing the capsule shell may cause drug loss, drug waste, and reduced efficacy.
  • some medicines need to be dissolved and absorbed in the intestine, and capsules protect the medicine from stomach acid.
  • the capsule is now extended to many other neighborhoods, such as cigarette capsules.
  • capsules are added to cigarette filters. Consumers squeeze the capsules at the right time when smoking, releasing flavors with special flavors, achieving interaction, improving mainstream smoke style, and enriching the role of smoke.
  • the object of the present invention is to provide an aqueous capsule.
  • Another object of the present invention is to provide a method for preparing the aqueous capsule.
  • the present invention is achieved by the following technical solutions.
  • the invention relates to an aqueous capsule.
  • the aqueous capsule is composed of 1-10 parts by weight of the capsule shell and 90-99 parts by weight of the water-soluble core fluid in the capsule shell; the strength of the capsule shell is 0.5-2.2 kg; the density of the water-soluble core fluid It is 0.9 to 1.3 g/cm 3 .
  • the capsule is made of photosensitive resin;
  • the water-soluble core fluid is composed of pure water and water-soluble substance in a weight ratio of 1:0.01-1.0.
  • the photosensitive resin is composed of 20-70 parts by weight of bisphenol A epoxy resin, 30-50 parts by weight of one or more selected from urethane acrylate, polyester acrylic resin , Polyether acrylic resin, acrylic dodecyl resin or other resins of acrylic resin and 1 to 5 parts by weight of photosensitizer;
  • the photosensitizer is one or more selected from 5-aminolevulinic acid, m-tetrahydroxyl A photosensitizer for chlorin, porphyrin tin, methylene blue, methylene blue, benzoporphyrin derivatives, benzoporphyrin derivatives monoacid, hypericin or hematoporphyrin monomethyl ether.
  • the water-soluble substance is one or more selected from water-soluble flavors and fragrances, plant extracts, extracts, food flavor substances, water-soluble polysaccharides, propylene glycol, glycerin , Honey, sodium chloride, potassium sorbate or potassium citrate.
  • the water-soluble flavors and fragrances are ethyl acetate, phenethyl alcohol, benzyl alcohol or furanone;
  • the plant extracts are alkaloids, volatile oil, tannin, sugar, amino acids , Protein, enzymes, organic acids, oils, waxes, pigments or inorganic plant extracts;
  • the extract is plum extract, hawthorn extract, tea extract or acid horn extract;
  • the food flavor substance It is malic acid, glutamic acid, sodium chloride or glucose;
  • the water-soluble polysaccharide is maltose or sucrose.
  • the invention also relates to the preparation method of the aqueous capsule.
  • the capsule wall material liquid prepared in step A and the water-soluble core liquid prepared in step B are prepared by a quantitative pump through a concentric dropper of a pill dropping device Dropped into normal temperature pure water protection liquid, irradiated with light during its falling process, the capsule wall material liquid gradually solidified and formed, wrapped and sealed with water-soluble core liquid to form water-based capsules; The water protection liquid is separated, and the collected aqueous capsules are washed with a 90% ethanol aqueous solution by volume and air-dried to obtain the aqueous capsules.
  • the density of the water-soluble core fluid is 0.9-1.3 g/cm 3 .
  • the density of the aqueous capsule wall material liquid is 1.0-1.3 g/cm 3 .
  • the dripping device consists of a coaxial double nozzle nozzle 1, a core liquid metering pump 21, a core liquid tank 3, a core liquid tube 4, a capsule wall material liquid tank 5, a capsule wall Material liquid pipe 6, capsule wall material liquid quantitative pump 22, protection liquid chamber 7, first light source generator 8, second riser 9, drop tank 10, discharge port 11, protection liquid return port 12, first Section protection liquid return pipe 131, protection liquid return pump 23, second section protection liquid return pipe 132, protection liquid return tank 14, first riser 15, first elevator and supporting screw 16, forming coil 17, second elevator And supporting screw 18, second light source generator 19 and main controller 20;
  • the core liquid metering pump 21 connects the core liquid tank 3 to the inner nozzle of the coaxial double nozzle nozzle 1 through the core liquid tube 4; meanwhile, the capsule wall material liquid metering pump 22 connects the capsule wall material liquid tank 5 through the capsule wall material liquid pipe 6 Connected to the outer nozzle of the coaxial double nozzle nozzle 1; the lower end of the coaxial double nozzle nozzle 1 is located in the top cavity mouth of the protection liquid cavity 7, and the end of the first riser 15 passes vertically through the center of the bottom of the protection liquid cavity 7 and the protection liquid cavity
  • the body 7 is connected, the other end is fixedly connected to the first lifting motor and the matching screw 16, and is connected to one end of the forming coil 17 through the hose; the first riser 15 is provided with its light directly directed to the first light source of the tube body 8; the other end of the forming coil 17 is connected to the bottom end of the second riser 9 through a hose, and its other end is located above the blanking trough 10 through a hose and
  • the lamp power of the first light source generator 8 and the second light source generator 19 is 18 to 500 w
  • the optical path is 50 to 100 cm
  • the light source generator 8 is a fluorescent lamp, incandescent lamp, LED UV lamp, LED lamp or searchlight.
  • the invention relates to an aqueous capsule.
  • the aqueous capsule is composed of 1-10 parts by weight of the capsule shell and 90-99 parts by weight of the water-soluble core fluid in the capsule shell; the strength of the capsule shell is 0.5-2.2 kg; the density of the water-soluble core fluid It is 0.9 to 1.3 g/cm 3 .
  • the capsule is made of photosensitive resin;
  • the photosensitive resin is a colloidal substance composed of a polymer.
  • These macromolecules are like scattered mesh-like fragments of chains. Under ultraviolet irradiation, these polymers combine to link polymer macromolecules, and at the same time, the polymer changes from a colloidal resin to a hard substance.
  • the photosensitive resin used in the present invention is composed of 20 to 70 parts by weight of bisphenol A type epoxy resin, 30 to 50 parts by weight of one or more selected from urethane acrylate, polyester acrylic resin, polyether acrylic resin, acrylic dodecyl acrylate Or other resins of acrylic resin and 1 to 5 parts by weight of photosensitizer;
  • the main role of bisphenol A epoxy resin in photosensitive resin is to form the basic skeleton of the capsule shell after curing.
  • the bisphenol A epoxy resin used in the present invention is a product currently on the market, for example, the product sold by Jiangyin Wanqian Chemical Co., Ltd. under the trade name bisphenol A epoxy resin.
  • the main role of other resins in photosensitive resin is to adjust the mechanical strength of the capsule shell and improve the physical and mechanical properties of bisphenol A epoxy resin.
  • the urethane acrylate, polyester acrylic resin, polyether acrylic resin, dodecyl acrylate or acrylic resin used in the present invention are all products currently on the market, such as the polyurethane sold under the trade name polyurethane acrylate by Zhengzhou Dacheng Coating Co., Ltd.
  • the main function of the photosensitizer in the photosensitive resin is that after receiving or absorbing the light energy, it itself undergoes a chemical change and decomposes into free radicals or cations, thereby initiating the polymerization reaction.
  • 5-aminolevulinic acid, m-tetrahydroxyphenyl chlorin, porphyrin tin, methylene blue, methylene blue, benzoporphyrin derivative, benzoporphyrin derivative monoacid, gold Hypericin and hematoporphyrin monomethyl ether photosensitizers are all products currently on the market, such as 5-aminolevulinic acid sold under the trade name 5-aminolevulinic acid hydrochloride by Xi'an Tianfeng Biotechnology Co., Ltd. .
  • the amount of other resin and photosensitizer when the amount of other resin and photosensitizer is within the range, if the amount of bisphenol A epoxy resin is less than 20 parts by weight, the strength of the capsule shell is not enough; if the bisphenol A epoxy resin If the dosage is higher than 70 parts by weight, the strength of the capsule shell is too high; therefore, it is reasonable that the dosage of bisphenol A epoxy resin is 20 to 70 parts by weight, preferably 32 to 58 parts by weight;
  • the amount of bisphenol A epoxy resin and photosensitizer is within the range, if the amount of other resin is less than 30 parts by weight, the strength of the capsule shell will be too high, the toughness is not enough, and the capsule is easy to break; if other If the amount of resin is higher than 50 parts by weight, the strength of the capsule shell is insufficient and the toughness is too strong; therefore, the amount of other resins is 30-50 parts by weight, preferably 35-45 parts by weight;
  • the amount of bisphenol A epoxy resin and other resins is within the range, if the amount of photosensitizer is less than 1 part by weight, the photocuring efficiency is too low, resulting in incomplete curing; if the amount of photosensitizer is higher than 5 Parts by weight, the curing efficiency is too high, which affects the shape of the capsule and will cause the appearance of the capsule to be deformed; therefore, the amount of photosensitizer used is 1 to 5 parts by weight, preferably 2 to 4 parts by weight;
  • the water-soluble core fluid is composed of pure water and water-soluble substances in a weight ratio of 1:0.01 to 1.0.
  • the water-soluble substance is one or more selected from water-soluble flavors and fragrances, plant extracts, extracts, food flavor substances, water-soluble polysaccharides, propylene glycol, glycerin, honey, sodium chloride, Water-soluble substance of potassium sorbate or potassium citrate.
  • the water-soluble essence and fragrance are ethyl acetate, phenethyl alcohol, benzyl alcohol or furanone;
  • the plant extract is alkaloid, volatile oil, tannin, sugar, amino acid, protein, enzyme, organic acid, oil and fat , Wax, pigments or inorganic plant extracts;
  • the extract is plum extract, hawthorn extract, tea extract or tamarind extract;
  • the food flavor substances are malic acid, glutamic acid, chlorine Sodium hydroxide or glucose;
  • the water-soluble polysaccharide is maltose or sucrose.
  • the water-soluble substances used in the present invention are all products commonly used in the technical field and sold on the current market.
  • the weight ratio of pure water to the water-soluble substance is less than 1:0.01, the flavor characteristics of the water-soluble flavor and fragrance are not obvious. ; If the weight ratio of pure water to water-soluble substances is greater than 1:1.0, the proportion of water-soluble flavors and fragrances is too high, which is not conducive to drip; therefore, the weight ratio of pure water to water-soluble substances is 1:0.01 ⁇ 1.0 is desirable It is preferably 1:0.1-0.5.
  • the invention also relates to the preparation method of the aqueous capsule.
  • the weight ratio of the water-soluble core fluid exceeds the above-mentioned range. If the weight ratio of pure water to water-soluble substances is less than 1:1.0, the requirement that the water-soluble core fluid is greater than the density of the protective fluid cannot be met; if the density of the water-soluble core fluid is less than the density of the protective fluid, the capsule is not in the protective fluid It will fall; if the weight ratio of pure water to water-soluble substance is higher than 1:0.01, the polymerization effect of the core fluid is not good, and the capsule will not polymerize into a circle during the falling process.
  • the density of the water-soluble core fluid is 0.9 to 1.3 g/cm 3 . It is undesirable that the density of the water-soluble core fluid exceeds the above-mentioned range. If the density of the water-soluble core fluid is less than 0.9 g/cm 3 , the water-soluble core fluid will fall significantly below the capsule wall during the fall of the water-based capsule Material liquid, out of heart or eccentric capsule. If the density of the water-soluble core fluid is greater than 1.3 g/cm 3 , the water-soluble core fluid will fall significantly higher than the capsule wall material liquid during the fall of the water-based capsule, and eccentric or solid capsules may also appear. Therefore, the density of the water-soluble core fluid is preferably 0.9 to 1.3 g/cm 3 , preferably 1.0 to 1.2 g/cm 3 .
  • the density of the aqueous capsule wall material liquid is 1.0 to 1.3 g/cm 3 .
  • the range of the density of the aqueous capsule wall material liquid is inappropriate, because the density of the aqueous capsule wall material liquid is greater than the density of the protective liquid; the protective liquid uses pure water, the density is close to 1.0g/cm 3 , if the capsule wall material If the density is less than 1.0g/cm 3 , the water-based capsule will fall slowly or not in the protective liquid, and the drip cannot be completed. If the density of the capsule wall material is greater than 1.3g/cm 3 , the water-based capsules fall too fast in the protective liquid, which is not conducive to molding and curing, and trailing capsules appear. Therefore, the density of the aqueous capsule wall material liquid is preferably 1.0 to 1.3 g/cm 3 , preferably 1.1 to 1.2 g/cm 3 .
  • the capsule wall material liquid prepared in step A and the water-soluble core liquid prepared in step B are prepared by a quantitative pump through a concentric dropper of a pill dropping device Dropped into normal temperature pure water protection liquid, irradiated with light during its falling process, the capsule wall material liquid gradually solidified and formed, wrapped and sealed with water-soluble core liquid to form water-based capsules; The water protection liquid is separated, and the collected aqueous capsules are washed with a 90% ethanol aqueous solution by volume and air-dried to obtain the aqueous capsules.
  • the uncured molded capsule naturally forms a spherical shape due to the cohesive force of the core liquid, it slowly falls in the protection liquid, and the capsule wall material liquid gradually After curing and molding, the water-soluble core liquid is wrapped and sealed to form an aqueous capsule.
  • the water-soluble core fluid when the water-soluble core fluid is 90 to 99 parts by weight, if the amount of the capsule wall material is less than 1 part by weight, the strength of the capsule is insufficient and it is easily broken, which is not conducive to storage; if the amount of the capsule wall material is higher than 10 By weight, the strength of the capsule is too high and it is not easy to break it.
  • the capsule wall material liquid is 1 to 10 parts by weight, if the amount of the water-soluble core liquid is less than 90 parts by weight, the strength of the capsule is too high, the roundness of the capsule is not enough, and it is not easy to break; 99 parts by weight, the capsule strength is not enough, easy to break, is not conducive to storage.
  • the dripping pill device used in the present invention is specifically referred to FIG. 1.
  • the dripping device consists of a coaxial double nozzle nozzle 1, a core liquid metering pump 21, a core liquid tank 3, a core liquid tube 4, a capsule wall material liquid tank 5, a capsule wall material liquid pipe 6, a capsule wall material liquid metering pump 22, Protection liquid chamber 7, first light source generator 8, second standpipe 9, blanking tank 10, discharge port 11, protection liquid return port 12, first section protection liquid return tube 131, protection liquid return pump 23, The second section of the protection liquid return pipe 132, the protection liquid return tank 14, the first riser 15, the first elevator and supporting screw 16, the forming coil 17, the second elevator and supporting screw 18, the second light source generator 19 and the general
  • the controller 20 is composed;
  • the core liquid metering pump 21 connects the core liquid tank 3 to the inner nozzle of the coaxial double nozzle nozzle 1 through the core liquid tube 4; meanwhile, the capsule wall material liquid metering pump 22 connects the capsule wall material liquid tank 5 through the capsule wall material liquid pipe 6 Connected to the outer nozzle of the coaxial double nozzle nozzle 1; the lower end of the coaxial double nozzle nozzle 1 is located in the top cavity mouth of the protection liquid cavity 7, and the end of the first riser 15 passes vertically through the center of the bottom of the protection liquid cavity 7 and the protection liquid cavity
  • the body 7 is connected, the other end is fixedly connected to the first lifting motor and the matching screw 16, and is connected to one end of the forming coil 17 through the hose; the first riser 15 is provided with its light directly directed to the first light source of the tube body 8; the other end of the forming coil 17 is connected to the bottom end of the second riser 9 through a hose, and the other end is located above the blanking trough 10 through the hose and the second
  • the lamp power of the first light source generator 8 and the second light source generator 19 used in the present invention is 18 to 500 W, and the optical path is 50 to 100 cm.
  • the first light source generator 8 and the second light source generator 19 are fluorescent lamps and incandescent lamps. , LED ultraviolet lamps, LED lamps or searchlights, these lamps are currently on the market products.
  • the general controller 20 used in the present invention controls the flow rate of each pump, the lifting height of each lifting motor, and the power of each light source generator.
  • the water capsule can wrap both pure water and water-soluble flavors and fragrances, plant extracts, extracts, food flavoring substances, water-soluble polysaccharides, propylene glycol, glycerin, honey, sodium chloride, potassium sorbate or citric acid Potassium and other substances.
  • the cigarettes added with the water-based capsule of the present invention have obvious aroma style, rich aroma, enhanced sweet and sweet characteristics, and improved smoke and mouthfeel characteristics. Specifically, the irritation of the mouth and throat is reduced, and there is a sense of sweetness and rejuvenation.
  • Figure 1 is a schematic diagram of the structure of a dripping pill device
  • 1-coaxial dual nozzle nozzle 21-core liquid metering pump; 22-capsule wall material liquid metering pump; 23-protection liquid return pump; 3-core liquid tank; 4-core liquid tube; 5-capsule wall material liquid tank ; 6-capsule liquid tube; 7-protection liquid cavity; 8-first light source generator; 9-second riser; 10-blanking trough; 11-discharge port; 12-protection liquid return port; 131-Section 1 protection liquid return pipe; 132-Section 2 protection liquid return pipe; 14-protection liquid return tank; 15-first riser; 16-first elevator and supporting screw; 17-forming coil; 18 -Second elevator and supporting screw; 19-Second light source generator; 20-General controller.
  • Example 1 Preparation of aqueous capsules
  • the preparation steps of the preparation method are as follows:
  • the water-soluble substance is dissolved in pure water under stirring to obtain a water-soluble core liquid with a density of 0.9 g/cm 3 ;
  • the capsule wall material liquid prepared in Step A and the water-soluble core liquid prepared in Step B are added to room temperature by a quantitative pump through a concentric dripper of a pill dropping device
  • the first light source generator 8 and the second light source generator 19 of the fluorescent lamp are irradiated with light under the conditions of a lamp power of 18w and an optical path of 50cm during the falling process, and the capsule wall material liquid gradually solidifies and wraps Seal the water-soluble core liquid to form water-based capsules; then separate the water-based capsules from the pure water protective liquid through the screen of the dropping trough.
  • the collected water-based capsules are washed with a 90% ethanol aqueous solution by volume and air-dried to obtain the water-based capsule.
  • the strength of the capsule is 1.6kg;
  • the dripping device consists of a coaxial double nozzle nozzle 1, a core liquid metering pump 21, a core liquid tank 3, a core liquid tube 4, a capsule wall material liquid tank 5, a capsule wall material liquid pipe 6, a capsule wall material liquid metering pump 22, Protection liquid chamber 7, first light source generator 8, second riser 9, blanking tank 10, discharge port 11, first section protection liquid return port 12, protection liquid return tube 131, second section protection liquid return
  • the pump 23 the protective liquid return pipe 132, the protective liquid return tank 14, the first riser 15, the first elevator and the supporting screw 16, the forming coil 17, the second elevator and the supporting screw 18, and the second light source generator 19;
  • the core liquid metering pump 21 connects the core liquid tank 3 to the inner nozzle of the coaxial double nozzle nozzle 1 through the core liquid tube 4; meanwhile, the capsule wall material liquid metering pump 22 connects the capsule wall material liquid tank 5 through the capsule wall material liquid pipe 6 Connected to the outer nozzle of the coaxial double nozzle nozzle 1; the lower end of the coaxial double nozzle nozzle 1 is located in the top cavity mouth of the protection liquid cavity 7, and the end of the first riser 15 passes vertically through the center of the bottom of the protection liquid cavity 7 and the protection liquid cavity
  • the body 7 is connected, and the other end is fixedly connected to the first lifting motor and the matching screw 16; the lower end of the first riser 15 is connected by a hose forming coil 17; the outer side of the first riser 15 is provided with light directly directed to the cavity
  • a light source generator 8 the bottom end of the second riser 9 is connected to one end of the forming coil 17 through a hose, and the other end of the second riser 9 is located in the
  • the aqueous capsule prepared in this example was subjected to sensory evaluation.
  • the preparation steps of the preparation method are as follows:
  • the water-soluble substance is dissolved in pure water under stirring to obtain a water-soluble core fluid with a density of 1.0 g/cm 3 ;
  • the dropping device described in Example 1 was used for dropping. According to 10 parts by weight of the capsule wall material liquid and 94 parts by weight of the water-soluble core liquid, the capsule wall material liquid prepared in Step A and the water-soluble core liquid prepared in Step B are added to the room temperature by a quantitative pump through the concentric dripper of the pill device In the pure water protection liquid, the first light source generator 8 and the second light source generator 19 of the incandescent lamp are irradiated with light under the conditions of lamp power 5w and optical path 80cm during the falling process, and the capsule wall material liquid gradually solidifies and forms. Encapsulate and seal the water-soluble core liquid to form an aqueous capsule; then separate the aqueous capsule from the pure water protective liquid through the screen of the dropping trough. The collected aqueous capsule is washed with a 90% ethanol aqueous solution by volume and air-dried to obtain the described Water-based capsules. The strength of the capsule shell is 1.8kg;
  • the water-based capsule prepared in this example was subjected to sensory evaluation, and the result of the evaluation was that the smoke moisturizing sensation was enhanced, the irritation was reduced, and the gas was reduced.
  • the preparation steps of the preparation method are as follows:
  • the dropping device described in Example 1 was used for dropping. According to 1 part by weight of the capsule wall material liquid and 90 parts by weight of the water-soluble core liquid, the capsule wall material liquid prepared in step A and the water-soluble core liquid prepared in step B are added to the room temperature by a quantitative pump through the concentric dripper of the pill device In the pure water protection liquid, the LED ultraviolet lamp first light source generator 8 and the second light source generator 19 are irradiated with light under the conditions of lamp power 150w and optical path 90cm during the falling process, and the capsule wall material liquid gradually solidifies and forms , Wrap and seal the water-soluble core liquid to form an aqueous capsule; then separate the aqueous capsule from the pure water protective liquid through the screen of the dropping trough, the collected aqueous capsule is washed with a 90% ethanol aqueous solution by volume, and air-dried to obtain the Water-based capsules.
  • the strength of the capsule is 2.0kg;
  • the water-based capsule prepared in this example was subjected to sensory evaluation, and the result of evaluation was that the smoke moisturization was enhanced, the irritation was reduced, the aroma characteristics were enhanced, and the smoke sweetness was enhanced.
  • the preparation steps of the preparation method are as follows:
  • the water-soluble substance is dissolved in pure water under stirring to obtain a water-soluble core liquid with a density of 1.2 g/cm 3 ;
  • the dropping device described in Example 1 was used for dropping. According to 2 parts by weight of the capsule wall material liquid and 99 parts by weight of the water-soluble core liquid, the capsule wall material liquid prepared in Step A and the water-soluble core liquid prepared in Step B are added to the room temperature by a quantitative pump through the concentric dripper of the pill device In the pure water protection liquid, the first light source generator 8 and the second light source generator 19 of the LED lamp are irradiated with light under the conditions of a lamp power of 500w and an optical path of 100cm during the falling process, and the capsule wall material liquid gradually solidifies and forms. Encapsulate and seal the water-soluble core liquid to form an aqueous capsule; then separate the aqueous capsule from the pure water protective liquid through the screen of the dropping trough. The collected aqueous capsule is washed with a 90% ethanol aqueous solution by volume and air-dried to obtain the described Water-based capsules. The strength of the capsule is 0.5kg;
  • the water-based capsule prepared in this example was subjected to sensory evaluation, and the result of the evaluation was that the smoke moisturization was enhanced, the irritation was reduced, and the aroma was enhanced.
  • the preparation steps of the preparation method are as follows:
  • the water-soluble substance was dissolved in pure water under stirring to obtain a water-soluble core fluid with a density of 1.3 g/cm 3 ;
  • the dropping device described in Example 1 was used for dropping.
  • the capsule wall material liquid prepared in Step A and the water-soluble core liquid prepared in Step B are added to room temperature by a quantitative pump through a concentric dripper of a pill dropping device
  • the first light source generator 8 and the second light source generator 19 of the searchlight are irradiated with light under the conditions of a lamp power of 300w and an optical path of 60cm during the falling process, and the capsule wall material liquid gradually solidifies and wraps Seal the water-soluble core liquid to form water-based capsules; then separate the water-based capsules from the pure water protective liquid through the screen of the dropping trough.
  • the collected water-based capsules are washed with a 90% ethanol aqueous solution by volume and air-dried to obtain the water-based capsule.
  • the strength of the capsule shell is 1.2 kg;
  • the water-based capsule prepared in this example is subjected to sensory evaluation, and the result of the evaluation is that the moist feeling of smoke is enhanced, the irritation is reduced, and the taste is relatively better.
  • the preparation steps of the preparation method are as follows:
  • the dropping device described in Example 1 was used for dropping.
  • the capsule wall material liquid prepared in step A and the water-soluble core liquid prepared in step B are added to room temperature by a quantitative pump through a concentric dripper of a pill dropping device
  • the LED ultraviolet lamp first light source generator 8 and the second light source generator 19 are irradiated with light under the conditions of lamp power 400w and optical path 70cm during the falling process, and the capsule wall material liquid gradually solidifies and forms , Wrap and seal the water-soluble core liquid to form an aqueous capsule; then separate the aqueous capsule from the pure water protective liquid through the screen of the dropping trough, the collected aqueous capsule is washed with a 90% ethanol aqueous solution by volume, and air-dried to obtain the Water-based capsules.
  • the strength of the capsule shell is 2.2kg;
  • the water-based capsule prepared in this example was subjected to sensory evaluation, and the result of evaluation was that the smoke moisturization was enhanced, the irritation was reduced, and the aroma characteristics were obvious.

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Abstract

一种水性胶囊及其制备方法，该水性胶囊由1～10重量份囊壳与90～99重量份位于囊壳中的水溶性芯液组成；该囊壳的强度是0.5～2.2kg；该水溶性芯液的密度是0.9～1.3g/cm3。添加水性胶囊的烟支，香气风格明显，香气丰富性，清甜香特征增强，烟气口感特征提升，具体表现为口腔和喉部刺激性降低，有回甜生津感。

Description

一种水性胶囊及其制备方法
本发明请求以申请号为CN 2018115692164、申请日为2018-12-21、发明名称为一种水性胶囊及其制备方法的中国发明专利申请为优先权。
【技术领域】
本发明属于卷烟烟支加工技术领域。更具体地，本发明涉及一种水性胶囊，还涉及所述水性胶囊的制备方法。
【背景技术】
胶囊用途广泛，囊壳具有屏障功能，可以防止芯内含物接触胶囊外部环境，而且还可以作为芯内含物以期望的释放速率释放的工具起作用。胶囊最早应用于医药卫生领域，医用胶囊装的药物，一般都是对食道和胃粘膜有刺激性的粉末或颗粒，或口感不好、易于挥发、在口腔中易被唾液分解，以及易吸入气管的药。这些药装入胶囊，既保护了药物药性不被破坏，也保护了消化器官和呼吸道。去掉胶囊壳可能会造成药物流失、药物浪费、药效降低。另外，有些药物需要在肠内溶解吸收，胶囊保护药物不被胃酸破坏。胶囊现在延申到其他众多邻域，例如烟用胶囊。胶囊作为一种卷烟新材料添加到卷烟过滤嘴中，消费者抽吸时适时挤碎胶囊，释放具有特殊香味的香精，达到建立互动性，改善主流烟气风格，丰富烟香的作用。
截至目前为止市场上并未出现此类能够对水或者水溶性芯液进行有效包裹的产品。针对目前存在的技术缺陷，本发明人通过在大量实验研究与分析，终于完成了本发明。
【发明内容】
[要解决的技术问题]
本发明的目的是提供一种水性胶囊。
本发明的另一个目的是提供所述水性胶囊的制备方法。
[技术方案]
本发明是通过下述技术方案实现的。
本发明涉及一种水性胶囊。
所述的水性胶囊由1～10重量份囊壳与90～99重量份位于囊壳中的水溶性芯液组成；所述囊壳的强度是0.5～2.2kg；所述水溶性芯液的密度是0.9～1.3g/cm 3。
根据本发明的一种优选实施方式，所述的囊壳是由光敏树脂制成的；所述水溶性芯液是由纯水与水溶性物质按照重量比1：0.01～1.0组成的。
根据本发明的另一种优选实施方式，所述的光敏树脂由20～70重量份双酚A型环氧树脂、30～50重量份一种或多种选自聚氨酯丙烯酸酯、聚酯丙烯酸树脂、聚醚丙烯酸树脂、丙烯酸十二脂或丙烯酸树脂的其它树脂与1～5重量份光敏剂组成；所述的光敏剂是一种或多种选自5-氨基酮戊酸、间-四羟基苯基二氢卟酚、初卟啉锡、亚甲基蓝、亚甲蓝、苯并卟啉衍生物、苯并卟啉衍生物单酸、金丝桃素或血卟啉单甲醚的光敏剂。
根据本发明的另一种优选实施方式，所述的水溶性物质是一种或多种选自水溶性香精香料、植物提取物、浸膏、食品风味物质、水溶性多糖、丙二醇、丙三醇、蜂蜜、氯化钠、山梨酸钾或柠檬酸钾的水溶性物质。
根据本发明的另一种优选实施方式，所述的水溶性香精香料是乙酸乙酯、苯乙醇、苯甲醇或呋喃酮；所述的植物提取物是生物碱、挥发油、单宁、糖、氨基酸、蛋白质、酶、有机酸、油脂、蜡、色素或无机物的植物提取物；所述的浸膏是梅子浸膏、山楂浸膏、茶叶浸膏或酸角浸膏；所述的食品风味物质是苹果酸、谷氨酸、氯化钠或葡萄糖；所述的水溶性多糖是麦芽糖或蔗糖。
本发明还涉及所述水性胶囊的制备方法。
该制备方法的步骤如下：
A、水溶性芯液配制
按照纯水与水溶性物质的重量比1：0.01～1.0，在搅拌下将水溶性物质溶解于纯水中，得到所述的水溶性芯液；
B、胶囊壁材溶液配制
将20～70重量份双酚A型环氧树脂、30～50重量份其它树脂与1～5重量份光敏剂在常温下搅拌充分混匀，再避光静置保存12h以上，除去气泡，得到所述的胶囊壁材溶液；
C、水性胶囊滴制
按照1～10重量份胶囊壁材液与90～99重量份水溶性芯液，由定量泵通过滴丸装置同心圆滴头将步骤A配制的胶囊壁材液与步骤B配制的水溶性芯液滴加到常温纯净水保护液里，在其下落过程中进行光照射，胶囊壁材液逐渐固化成型，包裹密封水溶性芯液，形成水性胶囊；接着通过落料槽筛网将水性胶囊与纯净水保护液分离，收集的水性胶囊使用浓度为以体积计90％乙醇水溶液洗涤，风干，得到所述的水性胶囊。
根据本发明的一种优选实施方式，在步骤A中，所述水溶性芯液的密度是0.9～1.3g/cm 3。
根据本发明的另一种优选实施方式，在步骤B中，所述水性胶囊壁材液的密度是1.0～1.3g/cm 3。
根据本发明的另一种优选实施方式，所述的滴丸装置由同轴双喷嘴喷头1、芯液定量泵21、芯液槽3、芯液管4、胶囊壁材液槽5、胶囊壁材液管6、胶囊壁材液定量泵22、保护液腔体7、第一光源发生器8、第二立管9、落料槽10、出料口11、保护液回流口12、第一节保护液回流管131、保护液回流泵23、第二节保护液回流管132、保护液回流槽14、第一立管15、第一升降机及配套螺杆16、成型盘管17、第二升降机及配套螺杆18、第二光源发生器19与总控制器20组成；
芯液定量泵21通过芯液管4将芯液槽3与同轴双喷嘴喷头1的内喷头相连；同时，胶囊壁材液定量泵22通过胶囊壁材液管6将胶囊壁材液槽5与同轴双喷嘴喷头1的外喷头相连；同轴双喷嘴喷头1下端位于保护液腔体7顶部腔体口内，第一立管15一端垂直穿过保护液腔体7底部中心与保护液腔体7相连，另一端与第一升降电机及配套螺杆16固定连接，并且通过软管与成型盘管17一端相连；第一立管15外侧设置其光线直接对准该管体的第一光源发生器8；成型盘管17另一端通过软管与第二立管9底端相连，它的另一端通过软管和垂直于水平面的第二升降电机及配套螺杆18 而位于落料槽10上方；在落料槽10下部设置保护液回流口12，而在底部设置出料口11；保护液回流口12通过第一节保护液回流管131与保护液回流槽14上部相连；保护液回流槽14下部排液口通过第二节保护液回流管132和保护液回流泵23与保护液腔体7相连；在成型盘管17中心设置第二光源发生器19；由落料槽10底部出料口11排出水性胶囊，它经浓度为以体积计90％酒***溶液洗涤，风干，得到所述的水性胶囊。
根据本发明的另一种优选实施方式，第一光源发生器8和第二光源发生器19的灯功率是18～500w、光程是50～100cm，光源发生器8是日光灯、白炽灯、LED紫外灯、LED灯或探照灯。
下面将更详细地描述本发明。
本发明涉及一种水性胶囊。
所述的水性胶囊由1～10重量份囊壳与90～99重量份位于囊壳中的水溶性芯液组成；所述囊壳的强度是0.5～2.2kg；所述水溶性芯液的密度是0.9～1.3g/cm 3。
根据本发明，所述的囊壳是由光敏树脂制成的；光敏树脂是一种由高分子组成的胶状物质。这些高分子如同散乱的链式交连的篱网状碎片。在紫外线照射下，这些高分子结合成交联聚合物高分子，同时聚合物由胶质树脂转变成坚硬物质。
本发明使用的光敏树脂由20～70重量份双酚A型环氧树脂、30～50重量份一种或多种选自聚氨酯丙烯酸酯、聚酯丙烯酸树脂、聚醚丙烯酸树脂、丙烯酸十二脂或丙烯酸树脂的其它树脂与1～5重量份光敏剂组成；
双酚A型环氧树脂在光敏树脂中的主要作用是固化后构成囊壳的基本骨架。本发明使用的双酚A型环氧树脂是目前市场上销售的产品，例如由江阴万千化学品有限公司公司以商品名双酚A型环氧乙烯树脂销售的产品。
其它树脂在光敏树脂中的主要作用是调节囊壳的力学强度、改善双酚A型环氧乙烯树脂的物理机械性能。本发明使用的聚氨酯丙烯酸酯、聚酯丙烯酸树脂、聚醚丙烯酸树脂、丙烯酸十二脂或丙烯酸树脂都是目前市场上销售的产品，例如由郑州大成涂料有限公司以商品名聚氨酯丙烯酸酯销售 的聚氨酯丙烯酸酯、由上海釜顺国际贸易有限公司以商品名聚酯丙烯酸树脂销售的聚酯丙烯酸树脂、由佛山市三水灏诚合成树脂有限公司公司以商品名丙烯酸树脂销售的聚醚丙烯酸树脂。
光敏剂在光敏树脂中的主要作用是接受或吸收光能后，本身发生化学变化，分解为自由基或阳离子，从而引发聚合反应。本发明使用的5-氨基酮戊酸、间-四羟基苯基二氢卟酚、初卟啉锡、亚甲基蓝、亚甲蓝、苯并卟啉衍生物、苯并卟啉衍生物单酸、金丝桃素、血卟啉单甲醚光敏剂都是目前市场上销售的产品，例如由西安天丰生物科技有限公司以商品名5-氨基酮戊酸盐酸盐销售的5-氨基酮戊酸。
在本发明中，其它树脂与光敏剂的用量在所述范围内时，如果双酚A型环氧树脂的用量低于20重量份，则囊壳的强度不够；如果双酚A型环氧树脂的用量高于70重量份，则囊壳的强度过高；因此，双酚A型环氧树脂的用量为20～70重量份是合理的，优选地是32～58重量份；
双酚A型环氧树脂与光敏剂的用量在所述范围内时，如果其它树脂的用量低于30重量份，则囊壳的强度就会过高，韧度不够，胶囊易破裂；如果其它树脂的用量高于50重量份，则囊壳强度不够，韧性过强；因此，其它树脂的用量为30～50重量份是合适的，优选地是35～45重量份；
双酚A型环氧树脂与其它树脂的用量在所述范围内时，如果光敏剂的用量低于1重量份，则光固化效率过低，导致固化不完全；如果光敏剂的用量高于5重量份，则固化效率过高，影响胶囊的形状，会导致胶囊外观畸形；因此，光敏剂的用量为1～5重量份是恰当的，优选地是2～4重量份；
所述水溶性芯液是由纯水与水溶性物质按照重量比1：0.01～1.0组成的。
根据本发明，所述的水溶性物质是一种或多种选自水溶性香精香料、植物提取物、浸膏、食品风味物质、水溶性多糖、丙二醇、丙三醇、蜂蜜、氯化钠、山梨酸钾或柠檬酸钾的水溶性物质。其中，所述的水溶性香精香料是乙酸乙酯、苯乙醇、苯甲醇或呋喃酮；所述的植物提取物是生物碱、挥发油、单宁、糖、氨基酸、蛋白质、酶、有机酸、油脂、蜡、色素或无 机物的植物提取物；所述的浸膏是梅子浸膏、山楂浸膏、茶叶浸膏或酸角浸膏；所述的食品风味物质是苹果酸、谷氨酸、氯化钠或葡萄糖；所述的水溶性多糖是麦芽糖或蔗糖。本发明使用的水溶性物质都是在本技术领域里通常使用的、在目前市场上销售的产品。
在本发明中，如果纯水与水溶性物质的重量比小于1：0.01，则水溶性香精香料的风味特征不明显。；如果纯水与水溶性物质的重量比大于1：1.0，则水溶性香精香料的比重过高，不利于滴制；因此，纯水与水溶性物质的重量比为1：0.01～1.0是可取的，优选地是1：0.1～0.5。
本发明还涉及所述水性胶囊的制备方法。
该制备方法的步骤如下：
A、水溶性芯液配制
按照纯水与水溶性物质的重量比1：0.01～1.0，在搅拌下将水溶性物质溶解于纯水中，得到所述的水溶性芯液；
水溶性芯液的重量比超过所述的范围是不可取的。如果纯水与水溶性物质的重量比低于1：1.0，则无法满足水溶性芯液大于保护液的密度的要求；水溶性芯液的密度小于保护液的密度，则胶囊在保护液中不会下落；如果纯水与水溶性物质的重量比高于1：0.01，则芯液的聚合效果不好，胶囊在下落过程中不会聚合成圆形。
所述的水溶性物质已在前面描述过，故在此不再赘述。
根据本发明，所述水溶性芯液的密度是0.9～1.3g/cm 3。水溶性芯液的密度超过所述的范围是不可取的，如果水溶性芯液的密度小于0.9g/cm 3，则在水性胶囊下落过程中水溶性芯液的下落就会明显低于胶囊壁材液，出现实心或偏心胶囊。如果水溶性芯液的密度大于1.3g/cm 3，则在水性胶囊下落过程中水溶性芯液的下落就会明显高于胶囊壁材液，也会出现偏心或实心胶囊。因此，水溶性芯液的密度是0.9～1.3g/cm 3是可取的，优选地是1.0～1.2g/cm 3。
B、胶囊壁材溶液配制
将20～70重量份双酚A型环氧树脂、30～50重量份其它树脂与1～5重量份光敏剂在常温下搅拌充分混匀，再避光静置保存12h以上，除去气泡，得到所述的胶囊壁材溶液；
其中，双酚A型环氧树脂、其它树脂与光敏剂都已在前面描述过，故在此不再赘述。
根据本发明，所述水性胶囊壁材液的密度是1.0～1.3g/cm 3。水性胶囊壁材液的密度所述的范围是不合适的，因为水性胶囊壁材液的密度要大于保护液密度；保护液采用的是纯净水，密度接近1.0g/cm 3，如果胶囊壁材密度小于1.0g/cm 3，则水性胶囊在保护液里下落缓慢或不会下落，无法完成滴制。如果胶囊壁材密度大于1.3g/cm 3，则水性胶囊在保护液里下落过快，不利于成型与固化，出现拖尾胶囊。因此，水性胶囊壁材液的密度是1.0～1.3g/cm 3是可取的，优选地是1.1～1.2g/cm 3。
C、水性胶囊滴制
按照1～10重量份胶囊壁材液与90～99重量份水溶性芯液，由定量泵通过滴丸装置同心圆滴头将步骤A配制的胶囊壁材液与步骤B配制的水溶性芯液滴加到常温纯净水保护液里，在其下落过程中进行光照射，胶囊壁材液逐渐固化成型，包裹密封水溶性芯液，形成水性胶囊；接着通过落料槽筛网将水性胶囊与纯净水保护液分离，收集的水性胶囊使用浓度为以体积计90％乙醇水溶液洗涤，风干，得到所述的水性胶囊。
当胶囊壁材液与水溶性芯液滴加到常温纯净水保护液里时，未固化成型胶囊因所述芯液内聚力作用自然形成球形，它在保护液中慢慢下落，胶囊壁材液逐渐固化成型，于是包裹密封水溶性芯液，形成水性胶囊。
在本发明中，水溶性芯液为90～99重量份时，如果胶囊壁材的用量低于1重量份，则胶囊强度不够，易破碎，不利于储存；如果胶囊壁材的用量高于10重量份，则胶囊强度过高，不容易捏破。胶囊壁材液为1～10重量份时，如果水溶性芯液的用量低于90重量份，则胶囊强度过高，胶囊圆度不够，不容易捏破；如果水溶性芯液的用量高于99重量份，则胶囊强度不够，易破碎，不利于储存。
本发明使用的滴丸装置具体参见附图1。该滴丸装置由同轴双喷嘴喷头1、芯液定量泵21、芯液槽3、芯液管4、胶囊壁材液槽5、胶囊壁材液管6、胶囊壁材液定量泵22、保护液腔体7、第一光源发生器8、第二立管9、落料槽10、出料口11、保护液回流口12、第一节保护液回流管131、保护液回流泵23、第二节保护液回流管132、保护液回流槽14、第一立管15、第一升降机及配套螺杆16、成型盘管17、第二升降机及配套螺杆18、第二光源发生器19与总控制器20组成；
芯液定量泵21通过芯液管4将芯液槽3与同轴双喷嘴喷头1的内喷头相连；同时，胶囊壁材液定量泵22通过胶囊壁材液管6将胶囊壁材液槽5与同轴双喷嘴喷头1的外喷头相连；同轴双喷嘴喷头1下端位于保护液腔体7顶部腔体口内，第一立管15一端垂直穿过保护液腔体7底部中心与保护液腔体7相连，另一端与第一升降电机及配套螺杆16固定连接，并且通过软管与成型盘管17一端相连；第一立管15外侧设置其光线直接对准该管体的第一光源发生器8；成型盘管17另一端通过软管与第二立管9底端相连，它的另一端通过软管和垂直于水平面的第二升降电机及配套螺杆18而位于落料槽10上方；在落料槽10下部设置保护液回流口12，而在底部设置出料口11；保护液回流口12通过第一节保护液回流管131与保护液回流槽14上部相连；保护液回流槽14下部排液口通过第二节保护液回流管132和保护液回流泵23与保护液腔体7相连；在成型盘管17中心设置第二光源发生器19；由落料槽10底部出料口11排出水性胶囊，它经浓度为以体积计90％酒***溶液洗涤，风干，得到所述的水性胶囊。
本发明使用的第一光源发生器8和第二光源发生器19的灯功率是18～500w、光程是50～100cm，第一光源发生器8和第二光源发生器19是日光灯、白炽灯、LED紫外灯、LED灯或探照灯，这些灯都是目前市场上销售的产品。本发明使用的总控制器20控制各个泵的流速、各个升降电机的升降高度以及各个光源发生器的功率。
根据YC/T138-1998烟草及烟草制品感官评价标准，组织由15名评吸专家组成的评吸小组对含有本发明水性胶囊的烟支与没有这种水性胶囊的常规烟支进行了评吸，其评吸结果这些结果表明，添加本发明水性胶囊后， 香气风格明显，香气丰富性，清甜香特征增强，烟气口感特征提升，具体表现为口腔和喉部刺激性降低，有回甜生津感。
[有益效果]
本发明的有益效果是：
该水胶囊既能包裹纯水，又能包裹水溶性香精香料、植物提取物、浸膏、食品风味物质、水溶性多糖、丙二醇、丙三醇、蜂蜜、氯化钠、山梨酸钾或柠檬酸钾等物质。添加本发明水性胶囊的烟支，香气风格明显，香气丰富性，清甜香特征增强，烟气口感特征提升，具体表现为口腔和喉部刺激性降低，有回甜生津感。
【附图说明】
图1是滴丸装置的结构示意图；
图中：
1-同轴双喷嘴喷头；21-芯液定量泵；22-胶囊壁材液定量泵；23-保护液回流泵；3-芯液槽；4-芯液管；5-胶囊壁材液槽；6-胶囊壁材液管；7-保护液腔体；8-第一光源发生器；9-第二立管；10-落料槽；11-出料口；12-保护液回流口；131-第一节保护液回流管；132-第二节保护液回流管；14-保护液回流槽；15-第一立管；16-第一升降机及配套螺杆；17-成型盘管；18-第二升降机及配套螺杆；19-第二光源发生器；20-总控制器。
【具体实施方式】
通过下述实施例将能够更好地理解本发明。
实施例1：水性胶囊制备
该制备方法的制备步骤如下：
A、水溶性芯液配制
按照纯水与乙酸乙酯水溶性香精香料水溶性物质的重量比1：0.01，在搅拌下将水溶性物质溶解于纯水中，得到密度为0.9g/cm 3的水溶性芯液；
B、胶囊壁材溶液配制
将50重量份双酚A型环氧树脂、38重量份聚氨酯丙烯酸酯其它树脂与3重量份5-氨基酮戊酸光敏剂在常温下搅拌充分混匀，再避光静置保存12.0h，除去气泡，得到密度为1.0g/cm 3的胶囊壁材溶液；
C、水性胶囊滴制
按照8重量份胶囊壁材液与92重量份水溶性芯液，由定量泵通过滴丸装置同心圆滴头将步骤A配制的胶囊壁材液与步骤B配制的水溶性芯液滴加到常温纯净水保护液里，在其下落过程中由日光灯第一光源发生器8和第二光源发生器19在灯功率18w与光程50cm的条件下进行光照射，胶囊壁材液逐渐固化成型，包裹密封水溶性芯液，形成水性胶囊；接着通过落料槽筛网将水性胶囊与纯净水保护液分离，收集的水性胶囊使用浓度为以体积计90％乙醇水溶液洗涤，风干，得到所述的水性胶囊。所述囊壳的强度是1.6kg；
该滴丸装置由同轴双喷嘴喷头1、芯液定量泵21、芯液槽3、芯液管4、胶囊壁材液槽5、胶囊壁材液管6、胶囊壁材液定量泵22、保护液腔体7、第一光源发生器8、第二立管9、落料槽10、出料口11、第一节保护液回流口12、保护液回流管131、第二节保护液回流泵23、保护液回流管132、保护液回流槽14、第一立管15、第一升降机及配套螺杆16、成型盘管17、第二升降机及配套螺杆18与第二光源发生器19组成；
芯液定量泵21通过芯液管4将芯液槽3与同轴双喷嘴喷头1的内喷头相连；同时，胶囊壁材液定量泵22通过胶囊壁材液管6将胶囊壁材液槽5与同轴双喷嘴喷头1的外喷头相连；同轴双喷嘴喷头1下端位于保护液腔体7顶部腔体口内，第一立管15一端垂直穿过保护液腔体7底部中心与保护液腔体7相连，另一端与第一升降电机及配套螺杆16固定连接；第一立管15下端通过软管成型盘管17相连；第一立管15外侧设置其光线直接对准该腔体的第一光源发生器8，第二立管9底端通过软管与成型盘管17一端相连，它的另一端通过软管和垂直于水平面的第二升降电机及配套螺杆18而位于落料槽10上方；在落料槽10下部设置第一节保护液回流口12，第一节保护液回流口12通过保护液回流管131与保护液回流槽14上部相连；第二节保护液回流泵23通过保护液回流管132与保护液腔体7相连； 在成型盘管17中心设置第二光源发生器19；而在落料槽10底部设置出料口11，排出水性胶囊，它经浓度为以体积计90％酒***溶液洗涤，风干，得到所述的水性胶囊。
按照本申请说明书描述的评吸方法，对该实施例制备的水性胶囊进行感官评吸，其评吸结果：烟气润感增强，刺激性降低，清甜香特征增强，烟气口感特征有所提升，有回甜生津感。.
实施例2：水性胶囊制备
该制备方法的制备步骤如下：
A、水溶性芯液配制
按照纯水与蛋白质植物提取物水溶性物质的重量比1：0.08，在搅拌下将水溶性物质溶解于纯水中，得到密度为1.0g/cm 3的水溶性芯液；
B、胶囊壁材溶液配制
将60重量份双酚A型环氧树脂、42重量份聚酯丙烯酸树脂其它树脂与4重量份间-四羟基苯基二氢卟酚光敏剂在常温下搅拌充分混匀，再避光静置保存12.4h，除去气泡，得到密度为1.2g/cm 3的胶囊壁材溶液；
C、水性胶囊滴制
使用实施例1描述的滴丸装置进行滴制。按照10重量份胶囊壁材液与94重量份水溶性芯液，由定量泵通过滴丸装置同心圆滴头将步骤A配制的胶囊壁材液与步骤B配制的水溶性芯液滴加到常温纯净水保护液里，在其下落过程中由白炽灯第一光源发生器8和第二光源发生器19在灯功率5w与光程80cm的条件下进行光照射，胶囊壁材液逐渐固化成型，包裹密封水溶性芯液，形成水性胶囊；接着通过落料槽筛网将水性胶囊与纯净水保护液分离，收集的水性胶囊使用浓度为以体积计90％乙醇水溶液洗涤，风干，得到所述的水性胶囊。所述囊壳的强度是1.8kg；
按照本申请说明书描述的评吸方法，对该实施例制备的水性胶囊进行感官评吸，其评吸结果烟气润感增强，刺激性降低，杂气降低。
实施例3：水性胶囊制备
该制备方法的制备步骤如下：
A、水溶性芯液配制
按照纯水与梅子浸膏水溶性物质的重量比1：0.1，在搅拌下将水溶性物质溶解于纯水中，得到密度为1.1g/cm 3的水溶性芯液；
B、胶囊壁材溶液配制
将20重量份双酚A型环氧树脂、46重量份聚醚丙烯酸树脂其它树脂与1重量份初卟啉锡光敏剂在常温下搅拌充分混匀，再避光静置保存12.6h，除去气泡，得到密度为1.2g/cm 3的胶囊壁材溶液；
C、水性胶囊滴制
使用实施例1描述的滴丸装置进行滴制。按照1重量份胶囊壁材液与90重量份水溶性芯液，由定量泵通过滴丸装置同心圆滴头将步骤A配制的胶囊壁材液与步骤B配制的水溶性芯液滴加到常温纯净水保护液里，在其下落过程中由LED紫外灯第一光源发生器8和第二光源发生器19在灯功率150w与光程90cm的条件下进行光照射，胶囊壁材液逐渐固化成型，包裹密封水溶性芯液，形成水性胶囊；接着通过落料槽筛网将水性胶囊与纯净水保护液分离，收集的水性胶囊使用浓度为以体积计90％乙醇水溶液洗涤，风干，得到所述的水性胶囊。所述囊壳的强度是2.0kg；
按照本申请说明书描述的评吸方法，对该实施例制备的水性胶囊进行感官评吸，其评吸结果烟气润感增强，刺激性降低，香气特征增强，烟气甜感增强。
实施例4：水性胶囊制备
该制备方法的制备步骤如下：
A、水溶性芯液配制
按照纯水与谷氨酸食品风味物质水溶性物质的重量比1：0.4，在搅拌下将水溶性物质溶解于纯水中，得到密度为1.2g/cm 3的水溶性芯液；
B、胶囊壁材溶液配制
将30重量份双酚A型环氧树脂、30重量份丙烯酸十二脂其它树脂与2重量份苯并卟啉衍生物光敏剂在常温下搅拌充分混匀，再避光静置保存12.1h，除去气泡，得到密度为1.3g/cm 3的胶囊壁材溶液；
C、水性胶囊滴制
使用实施例1描述的滴丸装置进行滴制。按照2重量份胶囊壁材液与 99重量份水溶性芯液，由定量泵通过滴丸装置同心圆滴头将步骤A配制的胶囊壁材液与步骤B配制的水溶性芯液滴加到常温纯净水保护液里，在其下落过程中由LED灯第一光源发生器8和第二光源发生器19在灯功率500w与光程100cm的条件下进行光照射，胶囊壁材液逐渐固化成型，包裹密封水溶性芯液，形成水性胶囊；接着通过落料槽筛网将水性胶囊与纯净水保护液分离，收集的水性胶囊使用浓度为以体积计90％乙醇水溶液洗涤，风干，得到所述的水性胶囊。所述囊壳的强度是0.5kg；
按照本申请说明书描述的评吸方法，对该实施例制备的水性胶囊进行感官评吸，其评吸结果烟气润感增强，刺激性降低，香气增强。
实施例5：水性胶囊制备
该制备方法的制备步骤如下：
A、水溶性芯液配制
按照纯水与丙二醇水溶性物质的重量比1：0.8，在搅拌下将水溶性物质溶解于纯水中，得到密度为1.3g/cm 3的水溶性芯液；
B、胶囊壁材溶液配制
将70重量份双酚A型环氧树脂、34重量份丙烯酸树脂其它树脂与5重量份金丝桃素光敏剂在常温下搅拌充分混匀，再避光静置保存12.8h，除去气泡，得到密度为1.3g/cm 3的胶囊壁材溶液；
C、水性胶囊滴制
使用实施例1描述的滴丸装置进行滴制。按照4重量份胶囊壁材液与96重量份水溶性芯液，由定量泵通过滴丸装置同心圆滴头将步骤A配制的胶囊壁材液与步骤B配制的水溶性芯液滴加到常温纯净水保护液里，在其下落过程中由探照灯第一光源发生器8和第二光源发生器19在灯功率300w与光程60cm的条件下进行光照射，胶囊壁材液逐渐固化成型，包裹密封水溶性芯液，形成水性胶囊；接着通过落料槽筛网将水性胶囊与纯净水保护液分离，收集的水性胶囊使用浓度为以体积计90％乙醇水溶液洗涤，风干，得到所述的水性胶囊。所述囊壳的强度是1.2kg；
按照本申请说明书描述的评吸方法，对该实施例制备的水性胶囊进行感官评吸，其评吸结果烟气润感增强，刺激性降低，口感相对较佳。
实施例6：水性胶囊制备
该制备方法的制备步骤如下：
A、水溶性芯液配制
按照纯水与山梨酸钾水溶性物质的重量比1：1.0，在搅拌下将水溶性物质溶解于纯水中，得到密度为1.0g/cm 3的水溶性芯液；
B、胶囊壁材溶液配制
将40重量份双酚A型环氧树脂、50重量份聚氨酯丙烯酸酯其它树脂与3重量份血卟啉单甲醚光敏剂在常温下搅拌充分混匀，再避光静置保存12.2h，除去气泡，得到密度为1.1g/cm 3的胶囊壁材溶液；
C、水性胶囊滴制
使用实施例1描述的滴丸装置进行滴制。按照6重量份胶囊壁材液与98重量份水溶性芯液，由定量泵通过滴丸装置同心圆滴头将步骤A配制的胶囊壁材液与步骤B配制的水溶性芯液滴加到常温纯净水保护液里，在其下落过程中由LED紫外灯第一光源发生器8和第二光源发生器19在灯功率400w与光程70cm的条件下进行光照射，胶囊壁材液逐渐固化成型，包裹密封水溶性芯液，形成水性胶囊；接着通过落料槽筛网将水性胶囊与纯净水保护液分离，收集的水性胶囊使用浓度为以体积计90％乙醇水溶液洗涤，风干，得到所述的水性胶囊。所述囊壳的强度是2.2kg；
按照本申请说明书描述的评吸方法，对该实施例制备的水性胶囊进行感官评吸，其评吸结果烟气润感增强，刺激性降低，香气特征明显。

Claims (10)

  1. 一种水性胶囊，其特征在于所述的胶囊由1～10重量份囊壳与90～99重量份位于囊壳中的水溶性芯液组成；所述囊壳的强度是0.5～2.2kg；所述水溶性芯液的密度是0.9～1.3g/cm 3。
  2. 根据权利要求1所述的水性胶囊，其特征在于所述的囊壳是由光敏树脂制成的；所述水溶性芯液是由纯水与水溶性物质按照重量比1：0.01～1.0组成的。
  3. 根据权利要求2所述的水性胶囊，其特征在于所述的光敏树脂由20～70重量份双酚A型环氧树脂、30～50重量份一种或多种选自聚氨酯丙烯酸酯、聚酯丙烯酸树脂、聚醚丙烯酸树脂、丙烯酸十二脂或丙烯酸树脂的其它树脂与1～5重量份光敏剂组成；所述的光敏剂是一种或多种选自5-氨基酮戊酸、间-四羟基苯基二氢卟酚、初卟啉锡、亚甲基蓝、亚甲蓝、苯并卟啉衍生物、苯并卟啉衍生物单酸、金丝桃素或血卟啉单甲醚的光敏剂。
  4. 根据权利要求2所述的水性胶囊，其特征在于所述的水溶性物质是一种或多种选自水溶性香精香料、植物提取物、浸膏、食品风味物质、水溶性多糖、丙二醇、丙三醇、蜂蜜、氯化钠、山梨酸钾或柠檬酸钾的水溶性物质。
  5. 根据权利要求4所述的水性胶囊，其特征在于所述的水溶性香精香料是乙酸乙酯、苯乙醇、苯甲醇或呋喃酮；所述的植物提取物是生物碱、挥发油、单宁、糖、氨基酸、蛋白质、酶、有机酸、油脂、蜡、色素或无机物的植物提取物；所述的浸膏是梅子浸膏、山楂浸膏、茶叶浸膏或酸角浸膏；所述的食品风味物质是苹果酸、谷氨酸、氯化钠或葡萄糖；所述的水溶性多糖是麦芽糖或蔗糖。
  6. 根据权利要求1-5中任一项权利要求所述水性胶囊的制备方法，其特征在于该制备方法的步骤如下：
    A、水溶性芯液配制
    按照纯水与水溶性物质的重量比1：0.01～1.0，在搅拌下将水溶性物质溶解于纯水中，得到所述的水溶性芯液；
    B、胶囊壁材溶液配制
    将20～70重量份双酚A型环氧树脂、30～50重量份其它树脂与1～5重量份光敏剂在常温下搅拌充分混匀，再避光静置保存12h以上，除去气泡，得到所述的胶囊壁材溶液；
    C、水性胶囊滴制
    按照1～10重量份胶囊壁材液与90～99重量份水溶性芯液，由定量泵通过滴丸装置同心圆滴头将步骤A配制的胶囊壁材液与步骤B配制的水溶性芯液滴加到常温纯净水保护液里，在其下落过程中进行光照射，胶囊壁材液逐渐固化成型，包裹密封水溶性芯液，形成水性胶囊；接着通过落料槽筛网将水性胶囊与纯净水保护液分离，收集的水性胶囊使用浓度为以体积计90％乙醇水溶液洗涤，风干，得到所述的水性胶囊
  7. 根据权利要求6所述的制备方法，其特征在于在步骤A中，所述水溶性芯液的密度是0.9～1.3g/cm 3。
  8. 根据权利要求6所述的制备方法，其特征在于在步骤B中，所述水性胶囊壁材液的密度是1.0～1.3g/cm 3。
  9. 根据权利要求6所述的制备方法，其特征在于所述的滴丸装置由同轴双喷嘴喷头(1)、芯液定量泵(21)、芯液槽(3)、芯液管(4)、胶囊壁材液槽(5)、胶囊壁材液管(6)、胶囊壁材液定量泵(22)、保护液腔体(7)、第一光源发生器(8)、第二立管(9)、落料槽(10)、出料口(11)、保护液回流口(12)、第一节保护液回流管(131)、保护液回流泵(23)、第二节保护液回流管(132)、保护液回流槽(14)、第一立管(15)、第一升降机及配套螺杆(16)、成型盘管(17)、第二升降机及配套螺杆(18)、第二光源发生器(19)与总控制器(20)组成。
    芯液定量泵(21)通过芯液管(4)将芯液槽(3)与同轴双喷嘴喷头(1)的内喷头相连；同时，胶囊壁材液定量泵(22)通过胶囊壁材液管(6)将胶囊壁材液槽(5)与同轴双喷嘴喷头(1)的外喷头相连；同轴双喷嘴喷头(1)下端位于保护液腔体(7)顶部腔体口内，第一立立管(15)一 端垂直穿过保护液腔体(7)底部中心与保护液腔体(7)相连，另一端与第一升降电机及配套螺杆(16)固定连接，并且通过软管与成型盘管(17)一端相连；第一立管(15)外侧设置其光线直接对准该管体的第一光源发生器(8)；成型盘管(17)另一端通过软管与第二立管(9)底端相连，它的另一端通过软管和垂直于水平面的第二升降电机及配套螺杆(18)而位于落料槽(10)上方；在落料槽(10)下部设置保护液回流口(12)，而在底部设置出料口(11)；保护液回流口(12)通过第一节保护液回流管(131)与保护液回流槽(14)上部相连；保护液回流槽(14)下部排液口通过第二节保护液回流管(132)和保护液回流泵(23)与保护液腔体(7)相连；在成型盘管(17)中心设置第二光源发生器(19)；由落料槽(10)底部出料口(11)排出水性胶囊，它经浓度为以体积计90％酒***溶液洗涤，风干，得到所述的水性胶囊。
  10. 根据权利要求9所述的制备方法，其特征在于第一光源发生器(8)和第二光源发生器(19)的灯功率是18～500w、光程是50～100cm，第一光源发生器(8)和第二光源发生器(19)是日光灯、白炽灯、LED紫外灯、LED灯或探照灯。
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