WO2019108484A3 - Methods and compositions for modulating melanogenesis - Google Patents

Methods and compositions for modulating melanogenesis Download PDF

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Publication number
WO2019108484A3
WO2019108484A3 PCT/US2018/062477 US2018062477W WO2019108484A3 WO 2019108484 A3 WO2019108484 A3 WO 2019108484A3 US 2018062477 W US2018062477 W US 2018062477W WO 2019108484 A3 WO2019108484 A3 WO 2019108484A3
Authority
WO
WIPO (PCT)
Prior art keywords
compositions
methods
present disclosure
disclosed
modulating melanogenesis
Prior art date
Application number
PCT/US2018/062477
Other languages
French (fr)
Other versions
WO2019108484A2 (en
Inventor
Lijuan Zhang
Robin Carmichael
Original Assignee
Helix Biomedix, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Helix Biomedix, Inc. filed Critical Helix Biomedix, Inc.
Publication of WO2019108484A2 publication Critical patent/WO2019108484A2/en
Publication of WO2019108484A3 publication Critical patent/WO2019108484A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37—Coumarins, e.g. psoralen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/04—Preparations for care of the skin for chemically tanning the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Birds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Disclosed herein is a composition including a peptide consisting of the sequence of SEQ ID NO: 1 for increasing the production of melanin. The present disclosure provides methods and formulations for the treatment of pigmentation disorders or conditions. In some embodiments, provided herein are compositions and methods for sunless tanning. In other embodiments, the present disclosure is directed to such compositions that are formulated for use as pharmaceuticals and cosmetic products, and to medical devices comprising the disclosed compositions.
PCT/US2018/062477 2017-11-30 2018-11-26 Methods and compositions for modulating melanogenesis WO2019108484A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762592724P 2017-11-30 2017-11-30
US62/592,724 2017-11-30

Publications (2)

Publication Number Publication Date
WO2019108484A2 WO2019108484A2 (en) 2019-06-06
WO2019108484A3 true WO2019108484A3 (en) 2020-03-19

Family

ID=66665239

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2018/062477 WO2019108484A2 (en) 2017-11-30 2018-11-26 Methods and compositions for modulating melanogenesis

Country Status (2)

Country Link
TW (1) TW201924656A (en)
WO (1) WO2019108484A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030083243A1 (en) * 2001-03-28 2003-05-01 Owen Donald R. Short bioactive peptides
US20150152139A1 (en) * 2013-11-29 2015-06-04 Escape Therapeutics, Inc. Peptide Tyrosinase Activators

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030083243A1 (en) * 2001-03-28 2003-05-01 Owen Donald R. Short bioactive peptides
US20040229808A1 (en) * 2001-03-28 2004-11-18 Owen Donald R. Cosmetic compositions containing short bioactive peptides
US20150152139A1 (en) * 2013-11-29 2015-06-04 Escape Therapeutics, Inc. Peptide Tyrosinase Activators

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
LAW: "Bimatoprost in the treatment of eyelash hypotrichosis", CLINICAL OPHTHALMOLOGY, vol. 4, 13 April 2010 (2010-04-13), pages 349 - 358, XP009166954, DOI: 10.2147/OPTH.S6480 *

Also Published As

Publication number Publication date
WO2019108484A2 (en) 2019-06-06
TW201924656A (en) 2019-07-01

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