WO2018203577A1 - Microscope ophtalmique et unité d'amélioration de fonctionnalité - Google Patents

Microscope ophtalmique et unité d'amélioration de fonctionnalité Download PDF

Info

Publication number
WO2018203577A1
WO2018203577A1 PCT/JP2018/017568 JP2018017568W WO2018203577A1 WO 2018203577 A1 WO2018203577 A1 WO 2018203577A1 JP 2018017568 W JP2018017568 W JP 2018017568W WO 2018203577 A1 WO2018203577 A1 WO 2018203577A1
Authority
WO
WIPO (PCT)
Prior art keywords
optical system
optical
objective lens
oct
eye
Prior art date
Application number
PCT/JP2018/017568
Other languages
English (en)
Japanese (ja)
Inventor
福間　康文
和宏 大森
Original Assignee
株式会社トプコン
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2017165187A external-priority patent/JP6998103B2/ja
Priority claimed from JP2018056763A external-priority patent/JP7098370B2/ja
Application filed by 株式会社トプコン filed Critical 株式会社トプコン
Priority to US16/610,259 priority Critical patent/US11503996B2/en
Priority to EP18794987.0A priority patent/EP3620104B1/fr
Publication of WO2018203577A1 publication Critical patent/WO2018203577A1/fr

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/13—Ophthalmic microscopes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/102—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for optical coherence tomography [OCT]

Definitions

  • the present invention relates to an ophthalmic microscope such as a fundus camera, a slit lamp, and an ophthalmic surgical microscope having an illumination optical system for illuminating a subject's eye and an observation optical system for observing the illuminated subject's eye.
  • the ophthalmic microscope of the present invention has an OCT optical system capable of obtaining a tomographic image of an eye to be examined by optical coherence tomography (abbreviated as “OCT”), and includes an OCT optical system and an observation optical system. And can be made independent of each other, thereby increasing the degree of freedom in designing an ophthalmic microscope.
  • OCT optical coherence tomography
  • the present invention also relates to a function expansion unit that can be attached to and detached from an ophthalmic microscope and can add an OCT function to the ophthalmic microscope.
  • An ophthalmic microscope is a medical or examination device that can illuminate a patient's eye with an illumination optical system and magnify and observe the eye with an observation optical system including a lens or the like.
  • an ophthalmic microscope a microscope capable of obtaining a tomographic image of an eye to be examined by having an OCT optical system has been developed.
  • OCT is a technique for obtaining a tomographic image of a living body by configuring an interferometer using a light source with low coherence (short coherence distance). Specifically, using a light source with low coherence, this light is divided into two by a beam splitter, one light (measurement light) is scanned with a deflecting optical element and irradiated to a living tissue to be reflected or scattered. One light (reference light) is reflected by a mirror. The measurement light is reflected or scattered at various depths in the living tissue, and countless reflected or scattered light returns.
  • a light source with low coherence this light is divided into two by a beam splitter, one light (measurement light) is scanned with a deflecting optical element and irradiated to a living tissue to be reflected or scattered.
  • One light (reference light) is reflected by a mirror. The measurement light is reflected or scattered at various depths in the living tissue, and countless reflected or scattered light returns.
  • the intensity of the measurement light reflected at various depths of the living tissue can be detected by adjusting the position of the beam splitter and the mirror to change the path length of the reference light in various ways.
  • a tomographic image of a living tissue can be obtained.
  • an ophthalmic microscope having such an OCT optical system it is necessary to incorporate the OCT optical system into a microscope having an illumination optical system and an observation optical system so that light from the OCT optical system can enter the eye to be examined.
  • a method has been developed.
  • a Galileo system having an observation optical system composed of an observation optical system for the left eye and an observation optical system for the right eye of the observer, and having one objective lens through which the optical axes of the left and right observation optical systems are transmitted in common
  • the light of the OCT light source incident from the side of the objective lens is reflected by a reflecting member immediately above the objective lens and transmitted through the objective lens to be incident on the eye to be examined (Patent Document 1 and 2 etc.).
  • the ophthalmic microscope includes an optical axis of the left-eye observation optical system and an optical axis of the right-eye observation optical system.
  • the observation optical system composed of a pair of left and right lens groups 130, 140, 150, 170, and 180 that transmits the light, the optical axis of the left-eye observation optical system, and the optical axis of the right-eye observation optical system are common.
  • One objective lens 110 to transmit, OCT optical systems 200, 250, 450, 460, 470, and illumination optical systems 310, 320, 330 are provided.
  • the output light from the OCT light source 200 is emitted through the optical fiber 250, the direction is controlled by the two scanning mirrors 450 and 460, and then the beam combiner 340 emits the light from the illumination optical system.
  • the light merges with the illumination light, is reflected by the beam splitter 120, and enters the eye 1000 to be examined.
  • the optical axis of the observation optical system and the optical axis of the OCT optical system are commonly transmitted through one objective lens.
  • the Galileo type ophthalmic microscope as a method in which the optical axis of the OCT optical system does not pass through the objective lens, the light of the OCT light source incident from the side of the objective lens is reflected by the deflecting member directly under the objective lens, There is a method in which the light is incident on the eye without passing through the objective lens (Patent Documents 6 and 7). More specifically, in the ophthalmic microscope shown in FIG. 17 (drawing with reference to FIG. 3 of Patent Document 7), the objective lens 15 side is located below the objective lens 15 through which the optical axis of the observation optical system is transmitted.
  • conventional ophthalmic microscopes equipped with an OCT optical system include Galileo-type ophthalmic microscopes and Greenough-type ophthalmic microscopes, but Greenough-type ophthalmic microscopes require complicated optical designs. Met.
  • conventional Galileo ophthalmic microscopes as shown in Patent Documents 1 to 5, etc., the optical axis of the observation optical system and the optical axis of the OCT optical system are transmitted through one objective lens in common.
  • the observation optical system and the OCT optical system are not independent, the OCT optical system and the observation optical system are affected by each other, and the degree of freedom in optical design is limited. Met.
  • an object of the present invention is to develop a new type of ophthalmic microscope that increases the degree of freedom in optical design in a Galileo type ophthalmic microscope equipped with an OCT optical system.
  • the inventors of the present application have conducted intensive research.
  • the objective lens that transmits the optical axis of the observation optical system is arranged so that the optical axis of the OCT optical system does not transmit.
  • the observation optical system and the OCT optical system are independent and the degree of freedom in optical design is increased.
  • the deflection optical element for scanning of the OCT optical system and the OCT objective lens so as to have an optically substantially conjugate positional relationship, the measurement light can be irradiated in a wide irradiation range even with a small aperture OCT objective lens.
  • the present invention was completed.
  • this invention provides the following 1st invention regarding an ophthalmic microscope, the following 2nd invention regarding a function expansion unit, and the following 3rd invention regarding a function expansion set.
  • 1st invention has the illumination optical system which illuminates the eye to be examined, the observation optical system for the left eye for observing the eye to be examined illuminated with the illumination optical system, and the observation optical system for the right eye
  • an ophthalmic microscope having an optical path of measurement light for inspection and an OCT optical system including a deflection optical element that scans the measurement light
  • the observation optical system, the objective lens, and the OCT optical system are arranged so that the optical axis of the OCT optical system does not pass through the objective lens through which the optical axis of the observation optical system passes.
  • an OCT objective lens that transmits the optical axis of the OCT optical system.
  • the present invention relates to an ophthalmic microscope characterized in that the deflecting optical element and the OCT objective lens have an optically substantially conjugate positional relationship.
  • the OCT optical system is A first optical member for guiding light from the OCT light source in the first optical axis direction; A first reflecting member that guides light guided in the first optical axis direction in a second optical axis direction substantially orthogonal to the first optical axis direction; A second optical member that relays light guided in the second optical axis direction; A second reflecting member that guides light relayed by the second optical member in a third optical axis direction substantially orthogonal to the second optical axis direction; It is preferable that the OCT objective lens is disposed on the third optical axis so that light guided in the third optical axis direction can be irradiated to a predetermined portion of the eye to be examined.
  • the deflection optical element when the deflection optical element is composed of two pairs of deflection optical elements having different scanning directions, A relay optical system on the optical path between the two deflection optical elements; It is preferable that both of the two deflection optical elements have a substantially optically conjugate positional relationship with the OCT objective lens.
  • the objective lens has a partial shape of a circular lens, or a shape in which a circular lens has a notch or a hole, It is preferable that the optical axis of the OCT optical system passes through a portion where the objective lens does not exist, or a notch or a hole provided in the objective lens.
  • any one of the ophthalmic microscopes a circular lens or a lens composed of a circular lens portion is divided into two, One of the divided lenses is the objective lens, The other divided lens can be used as the OCT objective lens.
  • any one of the ophthalmic microscopes further includes an objective lens position control mechanism for adjusting a position of the objective lens or the OCT objective lens.
  • the OCT optical system is detachably unitized.
  • any one of the ophthalmic microscopes further includes a front lens that can be inserted and removed on an optical path between the eye to be examined and the objective lens in order to observe the retina of the eye to be examined.
  • the second invention includes an illumination optical system that illuminates the eye to be examined, an observation optical system for the left eye for observing the eye to be examined illuminated by the illumination optical system, and an observation optical system for the right eye
  • Function expansion unit for use in an ophthalmic microscope having an optical system and an objective lens through which the optical axis of the observation optical system for the left eye of the observation optical system and the optical axis of the observation optical system for the right eye are transmitted in common In A joint part detachable from the ophthalmic microscope;
  • the function expansion unit is attached to the ophthalmic microscope via the joint portion, the optical axis of the OCT optical system does not pass through the objective lens, and passes through the OCT objective lens
  • the present invention relates to a function expansion unit, wherein the deflection optical element and the OCT objective lens are in
  • the OCT optical system is A first optical member for guiding light from the OCT light source in the first optical axis direction; A first reflecting member that guides light guided in the first optical axis direction in a second optical axis direction substantially orthogonal to the first optical axis direction; A second optical member that relays light guided in the second optical axis direction; A second reflecting member that guides light relayed by the second optical member in a third optical axis direction substantially orthogonal to the second optical axis direction; It is preferable that the OCT objective lens is disposed on the third optical axis so that light guided in the third optical axis direction can be irradiated to a predetermined portion of the eye to be examined.
  • any one of the function expansion units when the deflection optical element is composed of two pairs of deflection optical elements having different scanning directions, A relay optical system on the optical path between the two deflection optical elements; It is preferable that both of the two deflection optical elements have a substantially optically conjugate positional relationship with the OCT objective lens. (12) It is preferable that any one of the function expansion units further includes a front lens that can be inserted into and removed from an optical path between the eye to be examined and the objective lens in order to observe the retina of the eye to be examined. (13) The third invention provides a function expansion set including any one of the function expansion units and a replacement objective lens for replacing the objective lens.
  • the replacement objective lens has a partial shape of a circular lens, or a shape in which a circular lens is provided with a notch or a hole,
  • the optical axis of the OCT optical system passes through a portion where the replacement objective lens does not exist, or a notch or a hole provided in the replacement objective lens.
  • the optical axis of the observation optical system passes through the objective lens, but the optical axis of the OCT optical system passes through the OCT objective lens provided separately from the objective lens.
  • the observation optical system and the OCT optical system are independent.
  • the ophthalmic microscope of the present invention can perform optical design without the observation optical system and the OCT optical system being affected by each other, and has the effect of increasing the degree of freedom in optical design.
  • the OCT objective lens having a small aperture can transmit measurement light.
  • the optical axis of the observation optical system of the ophthalmic microscope passes through the objective lens, but the optical axis of the OCT optical system of the function expansion unit is the objective lens. Is transmitted through the OCT objective lens.
  • the OCT optical system of the function expansion unit is independent of the observation optical system of the ophthalmic microscope, and can be unitized and has the effect of increasing the degree of freedom in optical design.
  • the function expansion unit and the function expansion set of the present invention can easily add the OCT function to the ophthalmic microscope. There is an effect. Further, the function expansion unit and function expansion set of the present invention have a small-diameter OCT objective lens because the scanning deflection optical element of the OCT optical system and the OCT objective lens are in a substantially optically conjugate positional relationship. However, the measurement light can be scanned over a wide irradiation range.
  • FIG. 4B is a cross-sectional view taken along a plane including the line segment AA ′ in FIG. It is drawing which shows typically the structure of an optical system as what looked at the side about the ophthalmic microscope of the 2nd Embodiment of this invention. It is drawing which shows typically the structure of an optical system about what was seen from the front about the ophthalmic microscope of the 2nd Embodiment of this invention. It is a perspective view of an OCT optical system about the ophthalmic microscope of the 2nd Embodiment of this invention.
  • FIG. 8 is a plan view of the OCT optical system shown in FIG. 7 for an ophthalmic microscope according to a second embodiment of the present invention. It is a side view of the OCT optical system shown in FIG.
  • FIG. 7 about the ophthalmic microscope of the 2nd Embodiment of this invention. It is a front view of the OCT optical system shown in FIG. 7 about the ophthalmic microscope of the 2nd Embodiment of this invention. It is drawing which shows typically the shape of the objective lens used for the ophthalmic microscope of the 3rd Embodiment of this invention.
  • FIG. 11A is a view seen from the direction of the optical axis of the objective lens
  • FIG. 11B is a cross-sectional view taken along a plane including the line segment AA ′ in FIG. It is drawing which shows typically the shape of the objective lens used for the ophthalmic microscope of the 4th Embodiment of this invention.
  • FIG. 12A is a view as seen from the direction of the optical axis of the objective lens
  • FIG. 12B is a cross-sectional view taken along a plane including the line segment AA ′ in FIG. It is drawing which shows typically the shape of the objective lens used for the ophthalmic microscope of the 5th Embodiment of this invention.
  • FIG. 13A is a view as seen from the direction of the optical axis of the objective lens
  • FIG. 13B is a cross-sectional view along a plane including the line segment AA ′ in FIG. It is drawing which shows typically the shape of the objective lens used for the ophthalmic microscope of the 6th Embodiment of this invention.
  • FIG. 14A is a view seen from the direction of the optical axis of the objective lens
  • FIG. 14B is a cross-sectional view taken along the plane including the line segment AA ′ in FIG. It is drawing which shows typically the shape of the objective lens used for the ophthalmic microscope of the 7th Embodiment of this invention, and the objective lens for OCT.
  • FIG. 15A is a view as seen from the direction of the optical axis of the objective lens
  • FIG. 15B is a cross-sectional view taken along the plane including the line segment AA ′ in FIG. It is drawing which quoted FIG. 1 of patent document 1.
  • FIG. It is drawing which quoted FIG. 3 of patent document 7.
  • FIG. 15A is a view seen from the direction of the optical axis of the objective lens
  • FIG. 14B is a cross-sectional view taken along the plane including the line segment AA ′ in FIG. It is drawing which quoted FIG. 1 of patent document 1.
  • FIG. It is drawing which quoted FIG. 3 of patent document 7.
  • An ophthalmic microscope of the present invention includes an illumination optical system that illuminates a subject eye, a left-eye observation optical system for observing the subject eye illuminated by the illumination optical system, and a right eye
  • An observation optical system having an observation optical system, an objective lens in which the optical axis of the observation optical system for the left eye of the observation optical system and the optical axis of the observation optical system for the right eye are transmitted in common, and the eye to be examined by optical coherence tomography
  • the present invention relates to an ophthalmic microscope having an optical path of measurement light for inspecting the light and an OCT optical system including a deflection optical element that scans the measurement light.
  • the ophthalmic microscope of the present invention includes an observation optical system, an objective lens, and an OCT optical system so that the optical axis of the OCT optical system does not pass through the objective lens through which the optical axis of the observation optical system passes.
  • an OCT objective lens that transmits the optical axis of the OCT optical system is provided.
  • the focus of the observation optical system (observation focal plane) and the focus of the OCT optical system (OCT scanning plane) are controlled by independently controlling the position of the objective lens and the OCT objective lens. Can be optically adjusted independently.
  • an optical design in which the OCT optical system is separated from the observation optical system and the OCT optical system can be attached to and detached from the ophthalmic microscope is also possible.
  • the ophthalmic microscope of the present invention is characterized in that the scanning deflection optical element and the OCT objective lens are in an optically conjugate positional relationship. Thereby, even when a small-diameter OCT objective lens is used, the measurement light can be scanned in a wide range.
  • the optically substantially conjugate positional relationship means that the deflecting optical element and the OCT objective lens are respectively located at two positions conjugate on the optical axis or at positions before and after thereof.
  • conjuggated positional relationship refers to a positional relationship in which when an image is formed at one position, the same image is formed at the other position.
  • the scanning deflection optical element of the OCT optical system may be one, or two or more.
  • at least one of the deflecting optical elements may be in an optically substantially conjugate positional relationship with the OCT objective lens.
  • two deflecting optical elements for example, one deflecting optical element is used as a deflecting optical element that scans in the x-axis direction, and the other deflecting optical element is used as a deflecting optical element that scans in the y-axis direction.
  • the measurement light can be scanned (scanned) in two dimensions.
  • the deflecting optical element that scans in the x-axis direction and the OCT objective lens have an optically substantially conjugate positional relationship, so that even if the aperture of the OCT objective lens is reduced, the x-axis direction can be reduced.
  • the scanning width can be kept large.
  • the deflection optical element that scans in the y-axis direction and the OCT objective lens optically substantially conjugate, the width of scanning in the y-axis direction can be achieved even if the aperture diameter of the OCT objective lens is reduced. Can be kept large.
  • both the deflection optical element that scans in the x-axis direction and the deflection optical element that scans in the y-axis direction should have a positional relationship that is optically substantially conjugate with the OCT objective lens.
  • the relay optical system is an optical element such as a lens and may be any optical system provided between two deflecting optical elements.
  • the relay optical system includes two or more lenses. It may be a lens group.
  • the relay optical system is not used. Any of the two deflecting optical elements can have a positional relationship that is substantially conjugate with the OCT objective lens.
  • ophthalmic microscope refers to a medical or inspection device that can enlarge and observe an eye to be examined, and includes not only humans but also animals.
  • Ophthalmic microscope includes, but is not limited to, a fundus camera, a slit lamp, an ophthalmic surgical microscope, and the like.
  • the “illumination optical system” includes an optical element for illuminating the eye to be examined.
  • the illumination optical system can further include a light source, but it may be one that guides natural light to the eye to be examined.
  • the “observation optical system” is configured to include an optical element that makes it possible to observe the eye to be inspected by return light reflected and scattered from the eye to be inspected illuminated by the illumination optical system. Is.
  • the observation optical system has a left-eye observation optical system and a right-eye observation optical system. When parallax is generated in an image obtained by the left and right observation optical systems, binocular vision is used. It is also possible to observe three-dimensionally.
  • observation optical system of the present invention may be one in which an observer can directly observe the eye to be examined through an eyepiece lens or the like, and can be observed by receiving light and imaging it with an imaging device or the like. It may be provided or may have both functions.
  • the “OCT optical system” includes an optical element that passes the OCT measurement light and a deflection optical element that scans the measurement light.
  • the OCT optical system can further include an OCT light source.
  • the “deflection optical element” may be any optical element that can scan the light by changing the direction of the light.
  • an optical element having a reflective portion whose direction changes such as a galvano mirror, a polygon mirror, a rotating mirror, a MEMS (Micro Electro Mechanical Systems) mirror, a deflection prism scanner,
  • An optical element that can change the direction of light by an electric field, an acoustooptic effect, or the like, such as an AO element, can be used.
  • optical elements used in the “illumination optical system”, “observation optical system”, and “OCT optical system” are not limited to these.
  • lenses, prisms, mirrors, and optical filters are used.
  • a diaphragm, a diffraction grating, a polarizing element, or the like can be used.
  • objective lens and “OCT objective lens” refer to a lens provided on the eye side in an ophthalmic microscope.
  • a front lens (loupe) that is temporarily inserted between the objective lens and the eye to be examined is not included in the “objective lens” in the present invention.
  • the “objective lens” in the present invention is an objective lens through which the optical axis of the left-eye observation optical system and the optical axis of the right-eye observation optical system are transmitted in common.
  • the light of the OCT optical system The axis does not pass through the objective lens.
  • the optical axis of the illumination optical system may or may not pass through the objective lens.
  • an illumination objective lens can be separately provided.
  • FIG. 1 is a schematic diagram showing the configuration of the optical system of the ophthalmic microscope according to the first embodiment as viewed from the side
  • FIG. 2 is a schematic diagram as viewed from the front
  • FIG. 3 is a drawing schematically showing the optical configuration of the OCT unit
  • FIG. 4 is a drawing schematically showing the shape of the objective lens.
  • the optical system of the ophthalmic microscope 1 includes an objective lens 2, an illumination optical system 300, an observation optical system 400, and an OCT optical system 500.
  • the objective lens 2, the illumination optical system 300, and the observation optical system 400 are accommodated in the ophthalmic microscope main body 6.
  • the OCT optical system 500 is housed in the function expansion unit 7.
  • the ophthalmic microscope main body 6 and the function expansion unit 7 are indicated by alternate long and short dash lines.
  • the ophthalmic microscope main body 6 and the function expansion unit 7 are detachably connected by a joint portion (not shown).
  • the illumination optical system 300 illuminates the eye 8 to be examined via the objective lens 2.
  • the illumination optical system 300 includes an illumination light source 9, an optical fiber 301, an exit aperture stop 302, a condenser lens 303, an illumination field stop 304, a collimator lens 305, and a reflection mirror 306.
  • the optical axis of the illumination optical system 300 is indicated by a dotted line O-300 in FIG.
  • the illumination light source 9 is provided outside the ophthalmic microscope main body 6.
  • One end of an optical fiber 301 is connected to the illumination light source 9.
  • the other end of the optical fiber is disposed at a position facing the condenser lens 303 inside the ophthalmic microscope main body 6.
  • the illumination light output from the illumination light source 9 is guided by the optical fiber 301 and enters the condenser lens 303.
  • An exit aperture stop 302 is provided at a position facing the exit port of the optical fiber 301 (fiber end on the condenser lens 303 side).
  • the exit aperture stop 302 acts to block a partial region of the exit aperture of the optical fiber 301.
  • the illumination field stop 304 is provided at a position (x position) optically conjugate with the front focal position U0 of the objective lens 2.
  • the collimating lens 305 turns the illumination light that has passed through the illumination field stop 304 into a parallel light flux.
  • the reflection mirror 306 reflects the illumination light converted into a parallel light beam by the collimator lens 305 toward the objective lens 2.
  • the reflected light passes through the objective lens 2 and irradiates the eye 8 to be examined.
  • Illumination light (a part) irradiated to the eye 8 is reflected and scattered by the tissue of the eye such as the cornea and the retina.
  • the reflected / scattered return light also called “observation light” passes through the objective lens 2 and enters the observation optical system 400.
  • the observation optical system 400 includes a variable power lens system 401, a beam splitter 402, an imaging lens 403, an image erecting prism 404, an eye width adjusting prism 405, a field stop 406, and an eyepiece lens 407. It is configured to include.
  • the optical axis of the observation optical system 400 is indicated by a dotted line O-400 in FIG.
  • the observation optical system 400 is used for observing the eye 8 to be examined illuminated by the illumination optical system 300 through the objective lens 2.
  • the OCT optical system 500 includes an OCT unit 10, an optical fiber 501, a collimating lens 502, an illumination field stop 509, scanning mirrors 503a and 503b, a relay optical system 504, a first lens group 505, and a reflection mirror. 508, a second lens group 506, and an OCT objective lens 507.
  • the optical axis of the OCT optical system 500 is indicated by a dotted line O-500 in FIG.
  • a hole is provided in the center of the objective lens 2.
  • the optical axis O-500 of the OCT optical system does not pass through the objective lens 2 because it passes through the hole of the objective lens 2.
  • the optical axis O-500 of the OCT optical system passes through the OCT objective lens 507.
  • the OCT optical system and the observation optical system are independent.
  • the OCT unit 10 divides light from the OCT light source having low coherence (short coherence distance) into measurement light and reference light.
  • the measurement light is guided by the OCT optical system 500 and applied to the eye 8 to be examined, reflected and scattered in the tissue of the eye to be examined, and is returned to the OCT unit 10 as return light.
  • the OCT unit 10 detects interference between the return light of the measurement light and the reference light. Thereby, a tomographic image of the tissue of the eye to be examined can be obtained.
  • the OCT unit 10 is provided outside the function expansion unit 7, but one end of an optical fiber 501 is connected to the function expansion unit 7.
  • the measurement light generated by the OCT unit 10 is emitted from the other end of the optical fiber 501.
  • the emitted measurement light passes through the collimator lens 502, illumination field stop 509, scanning mirrors 503a and 503b, relay optical system 504, first lens group 505, reflection mirror 508, second lens group 506, OCT objective lens 507, and the like. Then, the return light of the measurement light irradiated to the eye 8 and reflected / scattered by the tissue of the eye 8 travels in the opposite direction and enters the other end of the optical fiber 501.
  • the front lens 14 When observing the retina of the fundus, the front lens 14 is inserted on the optical axes O-300, O-400, and O-500 in front of the eye of the subject's eye by a moving unit (not shown). In this case, the front focal position U0 of the objective lens 2 is conjugate with the retina of the fundus.
  • observation is performed with the front lens detached from the front of the subject's eye.
  • the collimating lens 502 converts the measurement light emitted from the other end of the optical fiber 501 into a parallel light beam.
  • the collimator lens 502 and the other end of the optical fiber 501 are configured to be relatively movable along the optical axis of the measurement light.
  • the collimator lens 502 is configured to be movable, but the other end of the optical fiber 501 may be configured to be movable along the optical axis of the measurement light.
  • the illumination field stop 509 is conjugate with the front focal position U0 of the OCT objective lens 507.
  • the scanning mirrors 503a and 503b in the OCT optical system are deflection optical elements that two-dimensionally deflect the measurement light that has been converted into a parallel light beam by the collimating lens 50).
  • the scanning mirror includes a first scanning mirror 503a having a deflection surface that can pivot about the x axis, and a galvanometer mirror including a second scanning mirror 503b having a deflection surface that can pivot about the y axis orthogonal to the x axis. It has become.
  • a relay optical system 504 is provided between the first scanning mirror 503a and the second scanning mirror 503b.
  • the irradiation area can be scanned linearly along the y-axis direction.
  • the scanning range of the measurement light is limited by the size (aperture) of the OCT objective lens 507.
  • the restriction due to the size (aperture) of the OCT objective lens 507 is reduced, and the aperture of the OCT objective lens is reduced.
  • a small scanning range can ensure a wide scanning range.
  • the second scanning mirror 503b is provided as a scanning deflecting optical element, and this is turned around the y-axis and irradiated with measurement light, the irradiated area can be scanned linearly along the x-axis direction.
  • the scanning range of the measurement light is limited by the size (aperture) of the OCT objective lens 507.
  • the restriction due to the size (aperture) of the OCT objective lens 507 is reduced, and the aperture of the OCT objective lens is reduced. Even if is small, a wide scanning range can be obtained.
  • a first scanning mirror 503a and a second scanning mirror 503b are provided as scanning deflecting optical elements, and both of them are swung to measure light.
  • the irradiation area of the measurement light is limited by the size (caliber) of the OCT objective lens 507.
  • a relay optical system 504 is provided between the first scanning mirror 503a and the second scanning mirror 503b.
  • the first scanning mirror 503a and the second scanning mirror 503b are both optically conjugate with the OCT objective lens 507.
  • portions having an optically conjugate positional relationship are indicated by + marks.
  • the first lens group 505 shown in FIG. 1 includes one or more lenses.
  • the second lens group 506 is also configured to include one or more lenses.
  • an OCT objective lens 507 is provided on the side in contact with the eye 8 to be examined.
  • the OCT objective lens is configured to be movable along the optical axis, and the focus of the OCT optical system can be adjusted by controlling the position of the OCT objective lens. Thereby, the focus of the OCT optical system can be adjusted to a position different from the focus of the observation optical system.
  • the optical axis O-500 of the OCT optical system does not pass through the objective lens 2 but passes through the OCT objective lens 507.
  • the OCT optical system is independent.
  • the observation optical system and the OCT optical system can be controlled independently, and the OCT optical system can be attached to and detached from the ophthalmic microscope. It is also possible to do.
  • FIG. 2 is a schematic diagram illustrating the configuration of the optical system of the ophthalmic microscope according to the first embodiment as viewed from the front.
  • the observation optical system is divided into an observation optical system 400L for the left eye of the observer and an observation optical system 400R for the right eye, and each has an observation optical path.
  • the optical axes of the left and right observation optical systems are indicated by dotted lines O-400L and O-400R in FIG.
  • the left and right observation optical systems 400L and 400R are a variable power lens system 401, an imaging lens 403, an image erecting prism 404, an eye width adjusting prism 405, a field stop 406, and an eyepiece, respectively. 407 is included.
  • the beam splitter 402 is included only in the observation optical system 400R for the right eye.
  • the variable magnification lens system 401 includes a plurality of zoom lenses 401a, 401b, and 401c.
  • the zoom lenses 401a, 401b, and 401c can be moved along the optical axes O-400L and O-400R of the left and right observation optical systems by a zoom mechanism (not shown). Thereby, the magnification at the time of observing or photographing the eye 8 to be examined is changed.
  • the beam splitter 402 of the observation optical system 400R for the right eye separates a part of the observation light guided along the observation optical system for the right eye from the eye 8 to be imaged.
  • the photographing optical system includes an imaging lens 1101, a reflection mirror 1102, and a television camera 1103.
  • the television camera 1103 includes an image sensor 1103a.
  • the image sensor 1103a is configured by, for example, a CCD (Charge Coupled Devices) image sensor, a CMOS (Complementary Metal Oxide Semiconductor) image sensor, or the like.
  • As the image sensor 1103a an element having a two-dimensional light receiving surface (area sensor) is used.
  • the light receiving surface of the image sensor 1103a is disposed at a position optically conjugate with the front focal position U0 of the objective lens 2.
  • the beam splitter and the imaging optical system may be in both the left and right observation optical systems.
  • a three-dimensional image can be obtained by acquiring images with parallax using the left and right imaging elements.
  • the TV camera image can be used to acquire an image of the observation site and also to track the OCT observation site. If the subject's eye moves during the OCT scan due to fixation eye movement or surgical operation of the subject's eye, the tomographic image obtained by OCT will shift, but the movement of the fundus is detected based on the TV camera image. By scanning the OCT optical system in accordance with the movement of the fundus, it is possible to obtain an OCT tomographic image without deviation.
  • the image erecting prism 404 converts the inverted image into an erect image.
  • the eye width adjustment prism 405 is an optical element for adjusting the distance between the left and right observation optical paths in accordance with the eye width of the observer (the distance between the left eye and the right eye).
  • the field stop 406 limits the observer's field of view by blocking the peripheral region in the cross section of the observation light.
  • the field stop 406 is provided at a position (x position) conjugate with the front focal position U0 of the objective lens 2.
  • the observation optical systems 400L and 400R may be configured to include a stereo variator configured to be detachable from the optical path of the observation optical system.
  • the stereo variator is an optical axis position changing element for changing the relative positions of the optical axes O-400L and O-400R of the left and right observation optical systems respectively guided by the left and right variable magnification lens systems 401.
  • the stereo variator is retracted to a retracted position provided on the observer side with respect to the observation optical path.
  • a sub-observation optical system 400S for use by the assistant observer is provided.
  • the sub-observation optical system 400 ⁇ / b> S receives the return light (observation light) reflected and scattered by the eye 8 illuminated by the illumination optical system via the objective lens 2 and an assistant eyepiece. Guide to 411.
  • the optical axis of the sub-observation optical system is indicated by a dotted line O-400S in FIG.
  • the sub-observation optical system 400S is also provided with a pair of left and right optical systems, and stereoscopic observation with binocular is possible.
  • the sub-observation optical system 400 ⁇ / b> S includes a prism 408, a reflection mirror 410, and an assistant eyepiece 411.
  • an imaging lens 409 is also disposed between the prism 408 and the reflection mirror 410.
  • Observation light from the eye 8 passes through the objective lens 2 and is reflected by the reflecting surface 408 a of the prism 408.
  • the observation light reflected by the reflecting surface 408a passes through the imaging lens 409, is reflected by the reflecting mirror 410, and is guided to the assistant eyepiece lens 411.
  • the observation optical systems 400L and 400R and the sub-observation optical system 400S are housed in the ophthalmic microscope main body 6.
  • the front lens 14 When observing the retina of the fundus, the front lens 14 is inserted on the optical axes O-400S, O-400L, and O-400R in front of the eye of the subject's eye by moving means (not shown). In this case, the front focal position U0 of the objective lens 2 is conjugate with the retina of the fundus.
  • observation is performed with the front lens detached from the front of the subject's eye.
  • FIG. 3 is a drawing schematically showing an optical configuration of the OCT unit 10 used in the ophthalmic microscope according to the first embodiment.
  • an ophthalmologic apparatus capable of executing Fourier domain type OCT will be described.
  • the ophthalmologic apparatus according to the embodiment can apply a swept source type OCT technique.
  • the configuration according to the present invention can also be applied to an ophthalmologic apparatus capable of executing a type other than the swept source type, for example, a spectral domain type OCT. As shown in FIG.
  • the OCT unit 10 divides the light emitted from the OCT light source unit 1001 into the measurement light LS and the reference light LR, and detects interference between the measurement light LS and the reference light LR that have passed through different optical paths. Interferometer is configured. Similar to a general swept source type OCT apparatus, the OCT light source unit 1001 includes a wavelength scanning type (wavelength sweeping type) light source capable of scanning (sweeping) the wavelength of emitted light. The OCT light source unit 1001 temporally changes the output wavelength at a near-infrared wavelength that cannot be visually recognized by human eyes. The light output from the OCT light source unit 1001 is indicated by a symbol L0.
  • a symbol L0 The light output from the OCT light source unit 1001 is indicated by a symbol L0.
  • the light L0 output from the OCT light source unit 1001 is guided to the polarization controller 1003 by the optical fiber 1002, and the polarization state thereof is adjusted.
  • the polarization controller 1003 adjusts the polarization state of the light L0 guided through the optical fiber 1002, for example, by applying external stress to the looped optical fiber 1002.
  • the light L0 whose polarization state is adjusted by the polarization controller 1003 is guided to the fiber coupler 1005 by the optical fiber 1004, and is divided into the measurement light LS and the reference light LR.
  • the reference light LR is guided to a collimator 1007 by an optical fiber 1006 and becomes a parallel light beam.
  • the reference light LR that has become a parallel light beam is guided to the corner cube 1010 via the optical path length correction member 1008 and the dispersion compensation member 1009.
  • the optical path length correction member 1008 acts as a delay unit for matching the optical path lengths (optical distances) of the reference light LR and the measurement light LS.
  • the dispersion compensation member 1009 acts as a dispersion compensation unit for matching the dispersion characteristics of the reference light LR and the measurement light LS.
  • the corner cube 1010 folds the traveling direction of the reference light LR that has become a parallel light beam by the collimator 1007 in the reverse direction.
  • the optical path of the reference light LR incident on the corner cube 1010 and the optical path of the reference light LR emitted from the corner cube 1010 are parallel. Further, the corner cube 1010 is movable in a direction along the incident optical path and the outgoing optical path of the reference light LR. By this movement, the length of the optical path (reference optical path) of the reference light LR is changed.
  • the reference light LR that has passed through the corner cube 1010 passes through the dispersion compensation member 1009 and the optical path length correction member 1008, is converted from a parallel light beam into a focused light beam by the collimator 1011, and enters the optical fiber 1012. Then, it is guided to the polarization controller 1013 and the polarization state of the reference light LR is adjusted.
  • the polarization controller 1013 has the same configuration as the polarization controller 1003.
  • the reference light LR whose polarization state is adjusted by the polarization controller 1013 is guided to the attenuator 1015 by the optical fiber 1014, and the light quantity is adjusted under the control of the arithmetic control unit 12.
  • the reference light LR whose light amount has been adjusted by the attenuator 1015 is guided to the fiber coupler 1017 by the optical fiber 1016.
  • the measurement light LS generated by the fiber coupler 1005 is guided to the collimator lens 502 by the optical fiber 501.
  • the measurement light incident on the collimator lens 502 includes an illumination field stop 509, scanning mirrors 503a and 503b, a relay optical system 504, a first lens group 505, a reflection mirror 508, a second lens group 506, Then, the eye 8 is irradiated through the OCT objective lens 507.
  • the measurement light is reflected and scattered at various depth positions of the eye 8 to be examined.
  • the backscattered light of the measurement light by the eye 8 travels in the same direction as the forward path in the reverse direction, and is guided to the fiber coupler 1005 as shown in FIG. 3 and then to the fiber coupler 1017 via the optical fiber 1018. To reach.
  • the fiber coupler 1017 generates interference light by combining (interfering) the measurement light LS incident through the optical fiber 1018 and the reference light LR incident through the optical fiber 1016.
  • the fiber coupler 1017 branches the interference light between the measurement light LS and the reference light LR at a predetermined branching ratio (for example, 50:50), thereby generating a pair of interference lights LC.
  • a pair of interference lights emitted from the fiber coupler 1017 are guided to the detector 1021 by two optical fibers 1019 and 1020, respectively.
  • the detector 1021 is, for example, a balanced photodiode (Balanced Photo Diode: hereinafter referred to as “BPD”) that has a pair of photodetectors that respectively detect a pair of interference light LC and outputs a difference between detection results.
  • BPD Balanced Photo Diode
  • the detector 1021 sends the detection result (detection signal) to the arithmetic control unit 12.
  • the arithmetic control unit 12 forms a cross-sectional image by performing Fourier transform or the like on the spectrum distribution based on the detection result obtained by the detector 1021 for each series of wavelength scans (for each A line).
  • the arithmetic control unit 12 displays the formed image on the display unit 13.
  • a Michelson type interferometer is used, but any type of interferometer such as a Mach-Zehnder type can be appropriately used.
  • FIG. 4 is a schematic diagram illustrating the shape of an objective lens used in the ophthalmic microscope according to the first embodiment.
  • 4A is a view seen from the direction of the optical axis of the objective lens
  • FIG. 4B is a cross-sectional view taken along a plane including the line segment AA ′ in FIG.
  • the objective lens 2 used in the first embodiment has a shape in which a hole 201 is provided at the center of a circular lens.
  • the optical path P-500 of the OCT optical system passes through the hole.
  • the optical path P-400L of the left-eye observation optical system, the optical path P-400R of the right-eye observation optical system, and the optical path P-300 of the illumination optical system are respectively It passes through different parts of the objective lens 2.
  • the optical path of the sub-observation optical system passes through the vicinity of the optical path P-400L of the left-eye observation optical system.
  • the cross-sectional shape of the objective lens 2 is a shape in which a hole is formed in the center of the convex lens.
  • Shape of the objective lens As the objective lens used in the ophthalmic microscope of the present invention, a circular lens can be used, but the angle formed by the optical axis of the OCT optical system and the optical axis of the observation optical system should be reduced. For this purpose, it is preferable to use an objective lens having a partial shape of a circular lens, or an objective lens having a shape in which a circular lens is provided with a notch or a hole.
  • the “partial shape of a circular lens” refers to a shape obtained by cutting off a part of a circular lens when viewed in plan from the optical axis direction of the lens, and is not limited to these.
  • a lens cut into a semicircular shape, a sector shape, a rectangular shape, or the like can be used so that the optical path of the observation optical system for the eye and the optical path of the observation optical system for the right eye are transmitted.
  • a shape in which a circular lens is provided with a notch or a hole means a shape in which a notch or a hole is provided in a plan view from the optical axis direction of the lens.
  • a lens having a shape in which a notch or a hole is provided in a portion through which the optical path of the OCT optical system transmits can be used.
  • an objective lens having a partial shape of the circular lens rather than providing a cutout or a hole in the circular lens.
  • the optical path of the OCT optical system can pass through a portion where the cut lens is not present in the circular lens, or a notch or a hole provided in the lens.
  • the angle formed by the optical axis of the OCT optical system and the optical axis of the observation optical system can be reduced without the optical axis of the OCT optical system being transmitted through the objective lens.
  • the angle formed by the optical axis of the OCT optical system and the optical axis of the observation optical system is preferably 1 to 15 °, more preferably The angle is preferably 4 to 10 °, more preferably 6 to 8 °.
  • a circular lens or a lens composed of a circular lens portion is divided into two, and one of the divided lenses is used as an objective lens through which the optical axis of the observation optical system is transmitted.
  • This lens can be an objective lens that transmits the optical axis of the OCT optical system.
  • a lens having the above-mentioned “circular lens partial shape” can be used as the “lens composed of a circular lens portion”. If such a divided lens is used and the position can be independently controlled, the observation optical system and the OCT optical system can be controlled independently.
  • the OCT optical system can be additionally incorporated as an extended function in an ophthalmic microscope having an observation optical system and an illumination optical system.
  • the present inventors have found that the optical path of the OCT optical system is bent twice so that it can be compactly incorporated in accordance with the original function of the microscope.
  • the OCT optical system is A first optical member for guiding light from the OCT light source in the direction of the first optical axis; A first reflecting member for guiding light guided in the first optical axis direction in a second optical axis direction substantially orthogonal to the first optical axis direction; A second optical member that relays light guided in the second optical axis direction; A second reflecting member that guides light relayed by the second optical member in a third optical axis direction substantially orthogonal to the second optical axis direction;
  • the OCT objective lens is preferably arranged on the third optical axis so that the light guided in the third optical axis direction can be irradiated to a predetermined portion of the eye to be examined.
  • FIG. 5 to 10 are drawings schematically showing a second embodiment which is another example of the ophthalmic microscope of the present invention.
  • FIG. 5 is a schematic side view of the ophthalmic microscope 1
  • FIG. 6 is a schematic front view thereof.
  • the ophthalmic microscope 1 is provided with an OCT apparatus 5.
  • the ophthalmic microscope 1 includes an illumination optical system 300 (not shown in FIG. 6), an observation optical system 400, and an OCT optical system 500.
  • the observation optical system 400 can observe a predetermined portion of the observation target (the eye 8 to be examined in FIGS. 5 and 6).
  • the illumination optical system 300 can illuminate a portion of the eye 8 to be observed.
  • the OCT apparatus 5 provided in the ophthalmic microscope 1 can acquire a tomographic image of the eye 8 to be examined.
  • the OCT optical system 500 is incorporated in the ophthalmic microscope 1 as a part of the OCT apparatus 5.
  • the OCT optical system 500, the front lens 14, and the reflecting surface (cornea, retina, etc.) of the eye 8 to be measured constitute a reciprocating light guide for measurement light.
  • the observation optical system 400 includes a right-eye observation optical system 400R and a left-eye observation optical system 400L. In FIG. 5, the entire configuration is shown for the right-eye observation optical system 400R, and only the objective lens 2 shared with the right-eye observation optical system 400R is shown for the left-eye observation optical system 400L. .
  • the optical axis O-400R of the right-eye observation optical system 400R and the optical axis O-400L of the left-eye observation optical system 400L pass through the objective lens 2, respectively.
  • the illumination optical system 300 and the observation optical system 400 are housed in the ophthalmic microscope main body 6.
  • the OCT optical system 500 is housed in the function expansion unit 7. 5 and 6, the ophthalmic microscope main body 6 is indicated by a one-dot chain line, and the function expansion unit 7 is indicated by a broken line.
  • the function expansion unit 7 is connected to the ophthalmic microscope main body 6 by a joint portion (not shown) so as to be removable / attachable.
  • the OCT apparatus 5 includes an OCT unit 10 and a function expansion unit 7.
  • the function expansion unit 7 accommodates an OCT optical system 500.
  • 7 is a perspective view of the OCT optical system 500
  • FIG. 8 is a plan view
  • FIG. 9 is a side view
  • FIG. 10 is a front view. 8 and 10
  • the collimating lens 502, the scanning function unit 503, and the first optical member 510 are not shown.
  • the OCT optical system 500 includes a collimating lens 502, a scanning function unit 503, a first optical member 510, a first reflecting member 511, a second optical member 512, a second reflecting member 513, and an OCT objective.
  • a lens 507 is included.
  • the scanning function unit 503 is a two-dimensional scanning mechanism having scanning mirrors 503a and 503b.
  • the scanning function unit 503 is provided on the back side (the side far from the observer) of the ophthalmic microscope main body 6.
  • the first optical member 510 is an OCT imaging lens, and guides the light scanned by the scanning function unit 503 in the direction of the first optical axis O-501.
  • the first optical axis O-501 is formed from the back to the front at the right outer position of the ophthalmic microscope body 6 when the ophthalmic microscope body 6 is viewed from the front.
  • the scanned light guides the first optical axis O-501 from the back toward the front.
  • the OCT objective lens 507 can be optically substantially conjugate to the positional relationship.
  • an optically conjugate position is indicated by +.
  • the light guided through the first optical axis O-501 is orthogonal to the direction of the first optical axis O-501 by the first reflecting member 511.
  • the light is guided in the direction of the second optical axis O-502.
  • the second optical axis O-502 is formed so as to face from the right outer side to the inner side of the ophthalmic microscope main body 6.
  • a second optical member 512 is disposed on the second optical axis O-502, and light that has passed through the second optical member 512 is directed downward by the second reflecting member 513 (substantially to the second optical axis O-502). Reflected in the orthogonal direction). This reflected light path is indicated by a third optical axis direction O-503.
  • the objective lens 2 has a partial shape of a circular lens in which the lens is cut so as to have a cut surface substantially parallel to the optical axis O-400.
  • the OCT objective lens 507 is accommodated in a portion where the lens of the circular lens is cut off.
  • the light guided in the third optical axis direction O-503 is focused by the OCT objective lens 507 at a predetermined position on the eye 8 side. 5 and 6, the front focal position U0 of the objective lens 2 is in front of the eye 8 to be examined, and the front lens 14 is disposed between the eye 8 to be examined and the front focal position U0.
  • the front lens 14 is a lens that is used when observing the retina of the fundus, and the front lens 14 has an optical axis O-300, O-400L, O-400R in front of the eye of the eye to be examined by moving means (not shown). Inserted on O-503. In this case, the front focal position U0 of the objective lens 2 is conjugate with the retina of the fundus. When observing the anterior segment of the cornea, iris, etc., the head lens 14 is detached from the front of the eye 8 to be examined.
  • the optical axis O-503 of the OCT optical system 500 passes through the OCT objective lens 507, and the optical axis O-503 of the OCT optical system 500 is separated from the optical axis O-400 of the observation optical system 400. ing. Therefore, the OCT optical system 500 and the observation optical system 400 are independent of each other.
  • FIG. 11 shows the shape of an objective lens used in a third embodiment which is another example of the ophthalmic microscope of the present invention.
  • FIG. 11A is a view seen from the direction of the optical axis of the objective lens
  • FIG. 11B is a cross-sectional view taken along a plane including the line segment AA ′ in FIG.
  • the objective lens 2 used in the third embodiment has a shape in which a cutout is provided in a part of a circular lens.
  • the optical path P-500 of the OCT optical system passes through the notched portion.
  • the cross-sectional shape of the objective lens 2 is a partial shape obtained by cutting off a part of the convex lens.
  • FIG. 12 shows the shape of an objective lens used in a fourth embodiment which is another example of the ophthalmic microscope of the present invention.
  • 12A is a view as seen from the direction of the optical axis of the objective lens
  • FIG. 12B is a cross-sectional view taken along a plane including the line segment AA ′ in FIG.
  • the objective lens 2 used in the fourth embodiment has a shape obtained by cutting a part of a circular lens into a rectangular shape, and the optical path P of the left-eye observation optical system.
  • -400L and the optical path P-400R of the right-eye observation optical system are transmitted through different portions of the objective lens 2, respectively.
  • the optical path P-500 of the OCT optical system and the optical path P-300 of the illumination optical system pass through the vicinity of the objective lens 2. Further, as shown in FIG. 12B, the cross-sectional shape of the objective lens 2 is a partial shape obtained by cutting off a part of the convex lens.
  • FIG. 13 shows the shape of an objective lens used in a fifth embodiment, which is another example of the ophthalmic microscope of the present invention.
  • FIG. 13A is a view as seen from the direction of the optical axis of the objective lens
  • FIG. 13B is a cross-sectional view along a plane including the line segment AA ′ in FIG.
  • the objective lens 2 used in the fifth embodiment has a shape obtained by cutting a part of a circular lens into a semicircular shape, and the optical path of the left-eye observation optical system.
  • P-400L, the optical path P-400R of the observation optical system for the right eye, and the optical path P-300 of the illumination optical system are transmitted through different portions of the objective lens 2, respectively.
  • the optical path P-500 of the OCT optical system passes through the vicinity of the objective lens 2.
  • the cross-sectional shape of the objective lens 2 is a partial shape obtained by cutting off a part of the convex lens.
  • FIG. 14 shows the shape of an objective lens used in a sixth embodiment, which is another example of the ophthalmic microscope of the present invention.
  • FIG. 14A is a view seen from the direction of the optical axis of the objective lens
  • FIG. 14B is a cross-sectional view taken along the plane including the line segment AA ′ in FIG.
  • the objective lens 2 used in the sixth embodiment has a shape in which a part of a circular lens is cut out in a crescent shape, and the optical path P of the left-eye observation optical system.
  • the optical path P-400L of the observation optical system for the right eye, and the optical path P-300 of the illumination optical system are transmitted through different portions of the objective lens 2, respectively.
  • the optical path P-500 of the OCT optical system passes through the vicinity of the objective lens 2.
  • the cross-sectional shape of the objective lens 2 is a partial shape obtained by cutting off a part of the convex lens.
  • FIG. 15 shows the shapes of an objective lens and an OCT objective lens used in a seventh embodiment, which is another example of the ophthalmic microscope of the present invention.
  • FIG. 15A is a view as seen from the direction of the optical axis of the objective lens
  • FIG. 15B is a cross-sectional view taken along the plane including the line segment AA ′ in FIG.
  • the objective lens and the OCT objective lens used in the eighth embodiment are obtained by dividing a circular lens into two.
  • the divided one lens 2 is used as an objective lens, and includes an optical path P-400L of the left-eye observation optical system, an optical path P-400R of the right-eye observation optical system, and an optical path P-300 of the illumination optical system. It is transparent.
  • the other divided lens 507 is used as an OCT objective lens and passes through the optical path P-500 of the OCT optical system. Further, as shown in FIG. 15B, the cross-sectional shapes of the objective lens 2 and the OCT objective lens 507 are formed by dividing the convex lens into two.
  • the function expansion unit of the present invention can be attached to and detached from an ophthalmic microscope, and can add an OCT function to an ophthalmic microscope.
  • the function expansion unit of the present invention includes an illumination optical system that illuminates an eye to be examined, and an optical path of an observation optical system for a left eye and an optical path of an observation optical system for a right eye for observing the eye to be examined illuminated by the illumination optical system And an objective lens through which the optical axis of the observation optical system for the left eye of the observation optical system and the optical axis of the observation optical system for the right eye transmit in common are used. Is.
  • the function expansion unit of the present invention comprises a joint part that can be attached to and detached from the ophthalmic microscope, An optical path of measurement light for inspecting the eye by optical coherence tomography, a deflection optical element that scans the measurement light, and an OCT optical system that includes an OCT objective lens,
  • the function expansion unit is attached to the ophthalmic microscope via the joint portion, the optical axis of the OCT optical system does not pass through the objective lens, and passes through the OCT objective lens,
  • the deflecting optical element and the OCT objective lens have an optically substantially conjugate positional relationship.
  • the OCT optical system of the function expansion unit of the present invention is independent of the observation optical system of the ophthalmic microscope, and can be unitized and has the effect of increasing the degree of freedom in optical design.
  • the function expansion unit of the present invention can be attached to and detached from the ophthalmic microscope via the joint portion, there is an effect that the OCT function can be easily added to the ophthalmic microscope.
  • the “joint part” of the function expansion unit of the present invention is not particularly limited as long as it allows the function expansion unit and the ophthalmic microscope to be attached and detached. It can be set as the joint part connected by matching, and the joint part connected using a screw
  • a specific example of the function expansion unit of the present invention is a function expansion unit (indicated by a dashed line indicated by reference numeral 7 in FIGS. 1 and 6) in the ophthalmic microscope of the first embodiment and the ophthalmic microscope of the second embodiment. As described in (enclosed part).
  • the function expansion set of the present invention is the above-mentioned 2.
  • a replacement objective lens for replacing the objective lens of the ophthalmic microscope and these are a set.
  • the replacement objective lens the 1-3. Can be used.
  • the objective lenses (FIGS. 4 and 11 to 15) used in the first embodiment and the third to seventh embodiments can be used.
  • the function expansion set of the present invention has an effect that the function expansion unit can be attached to and detached from the ophthalmic microscope via the joint portion, so that the OCT function can be easily added to the ophthalmic microscope.
  • the ophthalmic microscope, function expansion unit, and function expansion set of the present invention are useful in the industry for manufacturing ophthalmic medical devices.
  • FIGS. 1 to 15 The reference numerals used in FIGS. 1 to 15 indicate the following. DESCRIPTION OF SYMBOLS 1 Ophthalmic microscope 2 Objective lens 201 Objective lens hole 300 Illumination optical system 301 Optical fiber 302 Emission light stop 303 Condenser lens 304 Illumination field stop 305 Collimate lens 306 Reflection mirror 400 Observation optical system 400L Observation optical system 400R for the left eye Right Eye observation optical system 400S Sub-observation optical system 401 Zoom lens system 401a, 401b, 401c Zoom lens 402 Beam splitter 403 Imaging lens 404 Image erecting prism 405 Eye width adjustment prism 406 Field stop 407 Eyepiece 408 Prism 408a Prism Reflective surface 409 Imaging lens 410 Reflecting mirror 411 Assistant eyepiece 5 OCT apparatus 500 OCT optical system 501 Optical fiber 502 Collimating lens 503 Scanning function unit 503a, 503b Scanning mirror 504 Relay optical system 505 First lens group 506 Second lens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Eye Examination Apparatus (AREA)

Abstract

Le but de la présente invention est de développer un microscope ophtalmique de type galiléen qui est pourvu d'un système optique OCT et qui adopte un nouveau procédé qui augmente le degré de liberté dans la conception optique. La solution selon l'invention porte sur un microscope ophtalmique 1 ayant un système optique d'éclairage 300, un système optique d'observation 400, une lentille d'objectif 2, et un système optique OCT 500. Le microscope ophtalmique 1 est caractérisé en ceci : un axe optique O-500 du système optique OCT qui ne pénètre pas dans la lentille d'objectif 2 ; une lentille d'objectif OCT 507 à travers laquelle pénètre l'axe optique O-500 du système optique OCT ; et la lentille d'objectif OCT 507 et les éléments optiques de polarisation 503a, 503b pour le balayage du système optique OCT sont dans une relation de position en étant sensiblement couplés optiquement.
PCT/JP2018/017568 2017-05-02 2018-05-02 Microscope ophtalmique et unité d'amélioration de fonctionnalité WO2018203577A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US16/610,259 US11503996B2 (en) 2017-05-02 2018-05-02 Ophthalmic microscope and functionality enhancement unit
EP18794987.0A EP3620104B1 (fr) 2017-05-02 2018-05-02 Microscope ophtalmique et unité d'amélioration de fonctionnalité

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP2017-091997 2017-05-02
JP2017091997 2017-05-02
JP2017-165187 2017-08-30
JP2017165187A JP6998103B2 (ja) 2017-08-30 2017-08-30 顕微鏡及び機能拡張ユニット
JP2018056763A JP7098370B2 (ja) 2017-05-02 2018-03-23 眼科用顕微鏡及び機能拡張ユニット
JP2018-056763 2018-03-23

Publications (1)

Publication Number Publication Date
WO2018203577A1 true WO2018203577A1 (fr) 2018-11-08

Family

ID=64016154

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2018/017568 WO2018203577A1 (fr) 2017-05-02 2018-05-02 Microscope ophtalmique et unité d'amélioration de fonctionnalité

Country Status (1)

Country Link
WO (1) WO2018203577A1 (fr)

Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0866421A (ja) 1994-08-18 1996-03-12 Carl Zeiss:Fa 眼科手術装置
JP2008268852A (ja) 2006-11-06 2008-11-06 Carl Zeiss Surgical Gmbh Ｏｃｔシステムを備える眼科手術用顕微鏡
JP2008264488A (ja) 2007-04-24 2008-11-06 Carl Zeiss Surgical Gmbh Ｏｃｔシステムを備える手術用顕微鏡
JP2008264490A (ja) 2007-04-24 2008-11-06 Carl Zeiss Surgical Gmbh Ｏｃｔシステムを備える手術用顕微鏡
JP2010522055A (ja) 2007-03-20 2010-07-01 トプコン・ユーロペ・メディカル・ビーブイ． 眼を観察するための装置及び方法とｏｃｔモジュール
US20120092615A1 (en) * 2010-01-20 2012-04-19 Izatt Joseph A Systems and Methods for Surgical Microscope and Optical Coherence Tomography (OCT) Imaging
JP2012213634A (ja) * 2011-03-31 2012-11-08 Nidek Co Ltd 眼科用レーザ治療装置
JP2015519095A (ja) * 2012-04-05 2015-07-09 バイオプティジェン，インコーポレイテッド 光コヒーレンストモグラフィを使用する手術用顕微鏡、ならびに関連するシステムおよび方法
JP2015205176A (ja) * 2014-04-08 2015-11-19 株式会社トプコン 眼科装置
JP2016185178A (ja) 2015-03-27 2016-10-27 株式会社トプコン 眼科用顕微鏡システム
JP2016185177A (ja) 2015-03-27 2016-10-27 株式会社トプコン 眼科用顕微鏡
JP2016206348A (ja) 2015-04-20 2016-12-08 株式会社トプコン 眼科手術用顕微鏡
JP2017012429A (ja) * 2015-06-30 2017-01-19 株式会社トプコン 眼科用顕微鏡システム

Patent Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0866421A (ja) 1994-08-18 1996-03-12 Carl Zeiss:Fa 眼科手術装置
JP2008268852A (ja) 2006-11-06 2008-11-06 Carl Zeiss Surgical Gmbh Ｏｃｔシステムを備える眼科手術用顕微鏡
JP2010522055A (ja) 2007-03-20 2010-07-01 トプコン・ユーロペ・メディカル・ビーブイ． 眼を観察するための装置及び方法とｏｃｔモジュール
JP2008264488A (ja) 2007-04-24 2008-11-06 Carl Zeiss Surgical Gmbh Ｏｃｔシステムを備える手術用顕微鏡
JP2008264490A (ja) 2007-04-24 2008-11-06 Carl Zeiss Surgical Gmbh Ｏｃｔシステムを備える手術用顕微鏡
US8366271B2 (en) 2010-01-20 2013-02-05 Duke University Systems and methods for surgical microscope and optical coherence tomography (OCT) imaging
US20120092615A1 (en) * 2010-01-20 2012-04-19 Izatt Joseph A Systems and Methods for Surgical Microscope and Optical Coherence Tomography (OCT) Imaging
JP2012213634A (ja) * 2011-03-31 2012-11-08 Nidek Co Ltd 眼科用レーザ治療装置
JP2015519095A (ja) * 2012-04-05 2015-07-09 バイオプティジェン，インコーポレイテッド 光コヒーレンストモグラフィを使用する手術用顕微鏡、ならびに関連するシステムおよび方法
JP2015205176A (ja) * 2014-04-08 2015-11-19 株式会社トプコン 眼科装置
JP2016185178A (ja) 2015-03-27 2016-10-27 株式会社トプコン 眼科用顕微鏡システム
JP2016185177A (ja) 2015-03-27 2016-10-27 株式会社トプコン 眼科用顕微鏡
JP2016206348A (ja) 2015-04-20 2016-12-08 株式会社トプコン 眼科手術用顕微鏡
JP2017012429A (ja) * 2015-06-30 2017-01-19 株式会社トプコン 眼科用顕微鏡システム

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP3620104A4

Similar Documents

Publication Publication Date Title
JP6456711B2 (ja) 眼科手術用顕微鏡および眼科手術用アタッチメント
JP6490469B2 (ja) 眼科用顕微鏡システム
JP2018068732A (ja) 眼科装置
JP7178160B2 (ja) 顕微鏡及び機能拡張ユニット
US11871994B2 (en) Ophthalmologic microscope and function expansion unit
JP7165474B2 (ja) 眼科用顕微鏡
JP7049147B2 (ja) 眼科用顕微鏡及び機能拡張ユニット
JP2017023584A (ja) 眼科用顕微鏡
US11503996B2 (en) Ophthalmic microscope and functionality enhancement unit
EP3636137B1 (fr) Microscope ophtalmique et unité d'extension de fonction
JP6818391B2 (ja) 眼科用顕微鏡及び機能拡張ユニット
JP7098370B2 (ja) 眼科用顕微鏡及び機能拡張ユニット
JP6839902B2 (ja) 眼科用顕微鏡
WO2018203577A1 (fr) Microscope ophtalmique et unité d'amélioration de fonctionnalité
JP7213378B2 (ja) Ｏｃｔ機能拡張ユニット
JP2017012434A (ja) 眼科用顕微鏡システム
JP2019013803A (ja) 眼科手術用顕微鏡および眼科手術用アタッチメント
JP7117145B2 (ja) 眼科用顕微鏡
US12029485B2 (en) Ophthalmic microscope
JP7042663B2 (ja) 眼科用顕微鏡
JP6839901B2 (ja) 眼科用顕微鏡
JP6821443B2 (ja) 眼科用顕微鏡
WO2019044861A1 (fr) Microscope ophthalmique
JP2019010239A (ja) 眼科用顕微鏡

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 18794987

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

ENP Entry into the national phase

Ref document number: 2018794987

Country of ref document: EP

Effective date: 20191202