WO2018168989A1 - Liquid medicine administration system - Google Patents

Liquid medicine administration system Download PDF

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Publication number
WO2018168989A1
WO2018168989A1 PCT/JP2018/010170 JP2018010170W WO2018168989A1 WO 2018168989 A1 WO2018168989 A1 WO 2018168989A1 JP 2018010170 W JP2018010170 W JP 2018010170W WO 2018168989 A1 WO2018168989 A1 WO 2018168989A1
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WO
WIPO (PCT)
Prior art keywords
tip
distal end
tube
connector
needle
Prior art date
Application number
PCT/JP2018/010170
Other languages
French (fr)
Japanese (ja)
Inventor
有延学
沖原等
飯渕るり子
桝田多恵子
Original Assignee
テルモ株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by テルモ株式会社 filed Critical テルモ株式会社
Priority to JP2019506254A priority Critical patent/JP6975772B2/en
Publication of WO2018168989A1 publication Critical patent/WO2018168989A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/10—Tube connectors; Tube couplings
    • A61M39/12—Tube connectors; Tube couplings for joining a flexible tube to a rigid attachment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic

Definitions

  • the present invention relates to a chemical solution administration system including a chemical solution administration device having a chemical solution container filled with a chemical solution, and an administration device having a connector connectable to the chemical solution container.
  • a syringe pump type chemical solution administration device that administers a chemical solution filled in a chemical solution container into a living body under the action of a pusher is known.
  • This type of chemical solution administration device includes a barrel-type chemical solution container and a pusher mechanism that pushes out the chemical solution in the chemical solution container.
  • a tube with a needle is connected to the drug solution administration device as an administration device for transferring the drug solution from the drug solution administration device into the patient's body.
  • connection structure between a chemical solution administration device and a tube with a needle there is known a structure in which a connector provided at an end portion of a tube with a needle is connected to a distal end portion of a chemical solution container by screwing (for example, Japanese Patent No. 4759630). See the official gazette).
  • a sealing member rubber plug
  • the needle provided on the connector is sealed when the connector and the chemical solution container are connected. It penetrates the member.
  • the connector and the chemical container are connected by turning and screwing the connector. For this reason, when a needle pierces the sealing member, there is a possibility that coring that scrapes off the sealing member may occur.
  • the present invention has been made in consideration of such problems, and an object thereof is to provide a chemical solution administration system capable of suppressing the occurrence of coring when the connector and the chemical solution container are connected.
  • the present invention has a chemical solution container that can be filled with a chemical solution, a chemical solution administration device that includes a housing that contains the chemical solution container, and a connector that can be connected to the chemical solution container, An administration device for delivering a chemical solution to a patient, wherein the chemical solution container includes a barrel part that can be filled with the chemical solution therein, a protruding part from the trunk part in a distal direction, and a distal end A barrel having a tip opening provided on the tip opening, a sealing member made of an elastic material for liquid-tightly sealing the tip opening, and fixing the sealing member to the tip barrel A housing main body for holding the chemical solution container, and a guide that protrudes from the housing main body and surrounds the outer peripheral surface of the tip tube portion, and is disposed substantially concentrically with the tip tube portion.
  • the connector includes a needle tube having a needle point through which the sealing member can be pierced, and a connector body that holds the needle tube, and the connector body has the needle tube so that the needle point is a free end. And a guide receiving tube portion that protrudes from the base portion so as to surround the outer peripheral surface of the needle tube and is disposed substantially concentrically with the needle tube, and protrudes along the needle tube from the base portion and the needle tube. And an engaging portion that is engageable with the tip tube portion, and when the connector is connected to the chemical solution container, the needle tip is the sealing member.
  • the inner peripheral surface of the guide tube portion can contact the outer peripheral surface of the guide tube portion, and when the connector is connected to the drug solution container, the engaging portion is Inserted between the tube portion and the guide tube portion, and Characterized in that it is configured to engage the serial distal tube portion.
  • the engagement portion is engaged with the fixed member by the relative movement of the connector relative to the distal end tubular portion in the axial direction.
  • the main body of the connector is guided by the guide cylinder provided in the housing. Therefore, the needle is punctured into the sealing member without rotating with respect to the sealing member and without tilting. For this reason, it is possible to effectively suppress the occurrence of coring in which the needle scrapes off the sealing member when connecting the connector and the distal end cylindrical portion.
  • the fixing member has an engaging protrusion that engages with the engaging portion on an outer peripheral surface of the fixing member, and the engaging portion is engaged with the tip tube portion via the engaging protrusion of the fixing member. May be possible.
  • This configuration makes it possible to more stably guide the connector by the guide tube portion when the connector and the tip tube portion are connected.
  • the guide tube portion may have a grip portion for gripping the connector on the outer peripheral surface of the guide tube portion when the connector is connected to the chemical solution container.
  • the engaging portion between the engaging portion and the fixing member can be covered with the outer cylindrical portion, so that the engagement between the engaging portion and the fixing member can be reliably maintained.
  • a plurality of the engaging portions are arranged at intervals in the circumferential direction, and are provided at an engaging arm that is elastically deformable in the radial direction, and at a free end portion of each engaging arm, and protrudes inward in the radial direction. You may have a claw part.
  • the engagement portion can be engaged with the fixing member with an appropriate force, and an engagement structure that cannot be easily detached can be obtained.
  • the engagement portion may include a support tube portion protruding from the base portion, and the engagement arm may extend in a proximal direction from a base end of the support tube portion.
  • This configuration ensures that the engagement arm is elastically deformed when engaged, and the engaged state is reliably maintained after engagement.
  • the engaging arm and the claw portion may be formed in an arc shape along a circumference centering on the needle tube.
  • This configuration can effectively increase the engaging force between the engaging portion and the fixing member.
  • the engaging portion When the connector is connected to the chemical solution container, the engaging portion may be configured to slide on the outer peripheral surface of the fixing member.
  • the engaging portion When connecting the connector to the chemical solution container, the engaging portion may be configured to contact the outer peripheral surface of the fixing member before the needle tip starts to pierce the sealing member.
  • the housing body has an abutting outer peripheral surface adjacent to the proximal end of the guide tube portion, and in a state where the connection between the connector and the chemical solution container is completed, the protruding end portion of the guide receiving tube portion of the connector body is The housing may be configured to contact the contact outer peripheral surface.
  • This configuration suppresses the occurrence of rattling at the connection between the connector and the housing during use of the drug solution administration device after connection between the connector and the tip tube. For this reason, it is possible to prevent the user from feeling uneasy and to prevent a decrease in liquid tightness.
  • the distal end cylinder part has an outer diameter smaller than the outer diameter of the body part
  • the chemical solution container has a shoulder part that connects the body part and the distal end cylinder part
  • the fixing member A clamping portion that clamps the sealing member between the distal end surface of the distal end cylindrical portion and a peripheral wall portion extending in the proximal direction from the clamping portion, and the proximal end surface of the peripheral wall portion of the fixing member is You may adjoin or contact
  • This configuration prevents the fixing member from rattling with respect to the tip tube portion, so that the adhesion between the sealing member and the tip tube portion can be maintained. For this reason, liquid-tightness can be maintained satisfactorily and chemical liquid leakage can be prevented.
  • the distal end cylinder part has a rattling-preventing convex part that protrudes radially outward from the outer peripheral surface of the distal end cylinder part, and the inner peripheral surface of the peripheral wall part of the fixing member is the same as that of the distal end cylinder part. You may adjoin or contact
  • This configuration prevents the fixing member from rattling with respect to the tip tube portion, so that the adhesion between the sealing member and the tip tube portion can be maintained. For this reason, liquid-tightness can be maintained satisfactorily and chemical liquid leakage can be prevented.
  • the connector body includes a needle hub member having the base for holding the needle tube, a guide member having the guide receiving tube portion and the engagement portion, and joined to the needle hub member.
  • a positioning convex portion is provided on one of the proximal end surface of the hub member and the distal end surface of the guide member, and a positioning concave portion in which the positioning convex portion is fitted is provided on the other of the needle hub member and the guide member. It may be provided.
  • the fixing member includes a clamping portion that clamps the sealing member between a distal end surface of the distal end cylindrical portion, and an outer peripheral portion of the sealing member includes the distal end surface of the distal end cylindrical portion and the fixing member. It may be pinched
  • the fixing member includes a holding portion that holds the sealing member between a front end surface of the front end cylindrical portion, and a peripheral wall portion that extends in a proximal direction from the holding portion, and the peripheral wall portion of the fixing member
  • a locking protrusion for preventing the sealing member from falling off from the fixing member may be provided on the inner peripheral surface of the fixing member before the fixing member is attached to the distal end tubular portion.
  • the sealing member can be held in the fixing member when the fixing member is attached to the distal end tube portion in the assembly process. For this reason, the assembly
  • tip cylinder part can be performed easily.
  • the fixing member includes a sandwiching portion that sandwiches the sealing member with a distal end surface of the distal end cylindrical portion, and a distal end hole portion that penetrates a central portion of the sandwiching portion in the axial direction, and the sealing member
  • the member may have a tip protrusion that is inserted into the tip hole of the fixing member and protrudes in the tip direction from the tip of the fixing member.
  • This configuration makes it easy to wipe the surface of the sealing member protruding from the fixing member with alcohol cotton or the like before connecting the connector.
  • the sealing member may have a proximal end convex portion that is inserted into the distal end cylindrical portion and compressed radially inward by the inner peripheral surface of the distal end cylindrical portion.
  • This configuration can further improve the liquid tightness of the sealing member.
  • the fixing member includes a sandwiching portion that sandwiches the sealing member with a distal end surface of the distal end cylindrical portion, and a distal end hole portion that penetrates a central portion of the sandwiching portion in the axial direction, and the sealing member
  • the member has a distal end convex portion inserted into the distal end hole portion of the fixing member and a proximal end convex portion inserted into the distal end cylindrical portion, and the distal end convex portion is in a natural state before elastic deformation.
  • the base end convex part may have a symmetrical shape in the axial direction.
  • the present invention is a connector connectable to a chemical solution administration device having a chemical solution container that can be filled with a chemical solution and a housing that accommodates the chemical solution container, and the distal end of the distal end cylinder portion provided in the chemical solution container
  • a needle tube having a needle tip that can be pierced with a sealing member that seals the opening; and a connector main body that holds the needle tube, and the connector main body includes the needle tube such that the needle tip is a free end.
  • a guide receiving tube portion that protrudes from the base portion so as to surround the outer peripheral surface of the needle tube and is disposed substantially concentrically with the needle tube, and protrudes along the needle tube from the base portion and the needle tube.
  • An inner peripheral surface of the guide receiving tube portion is configured to contact an outer peripheral surface of a guide tube portion provided in the housing, and when the connector is connected to the drug solution container, It is configured to be inserted between the tip tube portion of the chemical solution container and the guide tube portion of the housing and to be engaged with the tip tube portion of the drug solution container.
  • the present invention is a chemical container that can be filled with a chemical solution, and can be connected to a connector provided in an administration device for feeding the chemical solution to a patient, and a trunk portion that can be filled with the chemical solution inside
  • a barrel having a tip tube portion protruding in the tip direction from the body portion and provided with a tip opening at the tip, and a sealing member made of an elastic material that seals the tip opening in a liquid-tight manner
  • a fixing member that fixes the sealing member to the distal end cylindrical portion, and the fixing member sandwiches the sealing member between the distal end surface of the distal end cylindrical portion and the center of the clamping portion.
  • the sealing member has a tip convex portion that is inserted into the tip hole portion of the fixing member and protrudes in the tip direction from the tip of the fixing member. It is characterized by.
  • the present invention is a sealing member made of an elastic material that liquid-tightly seals the tip opening of a chemical solution container that can be filled with a chemical solution
  • the chemical solution container includes a barrel portion that can be filled with the chemical solution therein. And sandwiching the sealing member between a barrel having a tip tube portion protruding from the body portion in the tip direction and provided with the tip opening at the tip, and a tip surface of the tip tube portion
  • a fixing member having a tip hole portion penetrating in the axial direction through a central portion of the clamping portion, a tip convex portion inserted into the tip hole portion of the fixing member, and the tip cylinder And having a base end convex portion inserted into the portion, and in a natural state before elastic deformation, the tip convex portion and the base end convex portion are symmetrical in the axial direction.
  • the present invention also provides a chemical solution administration device having a chemical solution container that can be filled with a chemical solution and a housing that accommodates the chemical solution container, to which a connector of an administration device for delivering the chemical solution to a patient can be connected.
  • the chemical solution container includes a barrel having a barrel portion that can be filled with the chemical solution, a distal end cylindrical portion that protrudes from the barrel portion in a distal direction and is provided with a distal end opening at the distal end, and the distal end
  • a sealing member made of an elastic material that seals the opening in a liquid-tight manner, and a fixing member that fixes the sealing member to the distal end tube portion
  • the housing includes a housing body that holds the chemical solution container;
  • the outer peripheral surface of the front end cylindrical portion is protruded from the housing main body and has a protective cylindrical portion arranged substantially concentrically with the front end cylindrical portion, and the fixing member is provided on the outer peripheral surface of the fixing member.
  • Engagement provided in the connector And has an engaging engagement
  • the present invention includes a chemical solution administration device having a chemical solution container that can be filled with a chemical solution, a housing that houses the chemical solution container, and a connector that can be connected to the chemical solution container, and the chemical solution is sent to a patient.
  • a method for connecting to an administration device comprising: a barrel portion that can be filled with the drug solution; and a distal end cylindrical portion that projects from the barrel portion in the distal direction and is provided with a distal end opening.
  • the chemical solution container including a barrel, a sealing member made of an elastic material that seals the tip opening in a liquid-tight manner, and a fixing member that fixes the sealing member to the tip tube portion, and holds the chemical solution container And a housing that protrudes from the housing body and surrounds an outer peripheral surface of the tip tube portion and has a guide tube portion that is disposed substantially concentrically with the tip tube portion. Stop member can be pierced A needle tube having a needle tip; and a connector main body for holding the needle tube, wherein the connector main body has a base portion for holding the needle tube so that the needle tip is a free end, and an outer peripheral surface of the needle tube from the base portion.
  • the connector having an engaging portion engageable with the distal end cylindrical portion is prepared, and the connector is directed toward the housing in a state where the needle tip of the connector is opposed to the sealing member of the chemical solution container.
  • the guide tube portion of the housing is inserted into the guide tube portion of the connector body, and the needle tip is sealed after the guide tube portion is inserted into the guide tube portion.
  • the engaging portion of the connector main body is inserted between the tip tube portion and the guide tube portion and penetrates the sealing member with the needle tube, and then the engagement portion and the tip tube are inserted. It is characterized by engaging the part.
  • FIG. 5A is an external perspective view of the fixing member
  • FIG. 5B is a cross-sectional perspective view of the fixing member
  • 6A is an external perspective view of the needle hub member and the needle tube
  • FIG. 6B is a cross-sectional perspective view of the needle hub member and the needle tube.
  • FIG. 7A is an external perspective view of a guide member
  • FIG. 7B is an external perspective view of the guide member from another angle.
  • the drug solution administration system 10 includes a drug body 12 (barrel) that forms a drug solution container that can be filled with a drug solution M, a drug solution administration device 12 that includes a housing 18 that houses the tube body 16, and a connector that can be connected to the cylinder body 16. 30 and an administration device 14 having 30.
  • the drug solution M is filled in the cylinder 16 in advance in the product provision state.
  • the medicinal solution administration device 12 continuously administers the medicinal solution M filled in the cylinder 16 into the living body over a relatively long time (for example, several minutes to several hours) under the pressing action of the pusher mechanism. .
  • the chemical solution administration device 12 may intermittently administer the chemical solution M into the living body.
  • the drug solution M include protein preparations, narcotic analgesics, diuretics and the like.
  • a patch-type needle-attached tube 15 is connected to the drug solution administration device 12 as the administration device 14, and the drug solution M discharged from the cylindrical body 16 has a needle. It is injected into the patient's body through the tube 15.
  • the drug solution administration device 12 further includes a gasket slidably disposed in the cylinder body 16, a pusher mechanism connected to the gasket, a drive unit that drives the pusher mechanism, and a drug solution.
  • a battery that supplies power necessary for the operation of the administration device 12 and a control unit that controls the drive unit are provided.
  • the pusher mechanism, the drive unit, the battery, and the control unit are accommodated in the housing 18.
  • the cylindrical body 16 is formed in a hollow cylindrical shape having a chemical solution chamber 16a therein.
  • the cylindrical body 16 includes a body portion 16b having a constant inner diameter and outer diameter in the axial direction, and a shoulder portion 16c whose inner diameter and outer diameter are tapered from the distal end of the body portion 16b toward the distal end. And a tip tube portion 16d protruding in the tip direction from the shoulder portion 16c.
  • a proximal end opening 16e is formed at the proximal end of the barrel portion 16b.
  • a distal end opening portion 16f communicating with the chemical solution chamber 16a is formed in the distal end cylindrical portion 16d.
  • the chemical solution M is filled in the cylindrical body 16 in advance.
  • a backlash prevention convex portion 16g for preventing backlash of the fixing member 26 described later is provided on the outer periphery of the base end portion of the distal end cylindrical portion 16d.
  • the rattling prevention convex portion 16g is formed in an annular shape that bulges outward in the radial direction and extends one round in the circumferential direction.
  • the base end of the rattling prevention convex part 16g is continued to the front end of the shoulder part 16c.
  • the fixing member 26 is located on the tip side (between the tip surface of the tip cylindrical portion 16d and the rattling prevention convex portion 16g) with respect to the rattle preventing convex portion 16g.
  • An engagement convex portion 16h that engages with the engagement claw 26a is provided.
  • the engaging convex portion 16h is formed in an annular shape protruding outward in the radial direction and extending once in the circumferential direction.
  • the engaging convex portion 16h has a locking surface 16h1 to which the engaging claw 26a is locked, and an inclined surface 16h2 that is formed on the distal end side with respect to the locking surface 16h1 and is reduced in diameter toward the distal direction.
  • the housing 18 includes a housing main body 20 that holds the cylindrical body 16, and a guide cylindrical portion 22 that protrudes from the housing main body 20, surrounds the outer peripheral surface of the distal end cylindrical portion 16d, and is disposed substantially concentrically with the distal end cylindrical portion 16d.
  • a guide tube portion 22 is integrally formed with the housing body 20.
  • the guide tube portion 22 may be a member manufactured as a separate component from the housing body 20 and fixed to the housing body 20.
  • the guide tube portion 22 is formed in a hollow cylindrical shape and is arranged concentrically with the tip tube portion 16d.
  • the outer peripheral surface 22a of the guide cylinder part 22 is a taper shape in which an outer diameter reduces toward a front-end
  • the outer peripheral surface 22a of the guide tube portion 22 may have a straight shape with an outer diameter constant in the axial direction.
  • the distal end surface 22b of the guide cylinder portion 22 is located on the distal end side with respect to the distal end surface of the distal end cylinder portion 16d.
  • the housing 18 has a top surface 18a and a bottom surface 18b.
  • the drug solution administration device 12 may be configured as a patch type that is used by being attached to the skin of a patient, for example.
  • the bottom surface 18b of the housing 18 is provided with a sheet-like sticking part (adhesive part) that can be stuck to the skin.
  • a peelable protective sheet is stuck on the sticking surface of the sticking part.
  • the medicinal solution administration device 12 may be configured as a type in which an attachment such as a hook or a clip is provided on the bottom surface 18b of the housing 18 and attached to a patient's clothes (for example, a waist portion of trousers). . Further, the cylindrical body 16 filled with the chemical M, the gasket slidably disposed in the cylindrical body 16, and the pusher mechanism are combined in advance and may be inserted into the housing 18 at the time of use. . In this case, it is preferable that a mounting portion for mounting the pusher mechanism on the cylinder body 16 is provided in the pusher mechanism and the cylinder body 16.
  • the medicinal solution administration device 12 further includes a sealing member 24 made of an elastic material that seals the distal end opening 16 f of the cylindrical body 16 in a liquid-tight manner, and a distal end opening of the cylindrical body 16.
  • a fixing member 26 that fixes the sealing member 24 to the distal end cylindrical portion 16d provided with 16f is provided.
  • the sealing member 24 is made of an elastic resin material such as a rubber material or an elastomer material, and is a plug that seals the tip opening 16f in a liquid-tight manner by being in close contact with the tip surface 16de of the tip tube portion 16d.
  • the sealing member 24 includes a sealing base portion 24a that forms a central portion in the thickness direction, a tip convex portion 24b that protrudes in the tip direction from the tip surface of the sealing base portion 24a, And a base end convex portion 24c protruding in the base end direction from the base end surface of the sealing base portion 24a.
  • the cross-sectional shapes perpendicular to the axial direction of the sealing base 24a, the tip convex portion 24b, and the base end convex portion 24c are all circular.
  • the outer diameters of the tip convex part 24b and the base end convex part 24c are smaller than the outer diameter of the sealing base part 24a.
  • the tip protrusion 24 b protrudes in the tip direction from the tip of the fixing member 26.
  • the outer peripheral portion of the sealing member 24 (the outer peripheral portion of the sealing base portion 24a) is sandwiched between the distal end surface of the distal end cylindrical portion 16d and the inner end surface of the fixing member 26 (the proximal end surface of a clamping portion 26d described later). It is compressed in the axial direction. For this reason, the front end surface 24a1 of the outer peripheral part of the sealing base 24a is in liquid-tight contact with the base end surface of the clamping part 26d.
  • the proximal end surface 24a2 of the outer peripheral portion of the sealing base portion 24a is in liquid-tight contact with the distal end surface of the distal end cylindrical portion 16d.
  • the tip convex portion 24b and the base end convex portion 24c are symmetrical in the axial direction. That is, the tip convex part 24b and the base end convex part 24c have the same outer diameter and the protruding height from the sealing base part 24a.
  • the outer diameter of the base end convex portion 24c is larger than the inner diameter of the distal end cylindrical portion 16d in a natural state before elastic deformation, but in FIG. 2, the proximal end convex portion 24c is elastically deformed and enters the inside of the distal end cylindrical portion 16d. It is out (fitted). For this reason, the base end convex portion 24c is in liquid-tight contact with the inner peripheral surface of the distal end cylindrical portion 16d.
  • the base end convex portion 24c may have a shape that does not liquid-tightly adhere to the inner peripheral surface of the distal end cylindrical portion 16d.
  • the outer diameter of the base end convex portion 24c is smaller than the inner diameter of the distal end cylindrical portion 16d.
  • the outer diameter of the distal convex portion 24b is smaller than the inner diameter of the distal cylindrical portion 16d, like the proximal convex portion 24c.
  • the fixing member 26 is a hollow cylindrical member attached to the distal end cylinder part 16d so as to cover the distal end cylinder part 16d, and holds the sealing member 24 between the distal end cylinder part 16d.
  • an engagement claw 26 a protruding inward in the radial direction is provided on the inner peripheral surface of the fixing member 26.
  • a plurality of engagement claws 26a are provided at intervals in the circumferential direction.
  • a claw forming hole portion 26c is provided at a position adjacent to the distal end side of the engagement claw 26a.
  • a pinching portion 26d protruding inward in the radial direction is provided at the distal end portion of the fixing member 26.
  • a tip hole portion 26d1 that penetrates the central portion of the sandwiching portion 26d in the axial direction is formed by the inner peripheral surface of the sandwiching portion 26d.
  • an annular locking projection 26e bulging inward in the radial direction is provided on the inner peripheral surface of the fixing member 26.
  • the locking protrusion 26e is a protrusion for preventing the sealing member 24 from falling off the fixing member 26 before the fixing member 26 is attached to the distal end cylindrical portion 16d.
  • the locking projection 26e is formed between the clamping portion 26d and the engagement claw 26a.
  • An engaging protrusion 26f is provided on the outer peripheral portion of the fixing member 26 so that an engaging portion 54 (described later) of the connector 30 can be engaged therewith.
  • the engagement protrusion 26f is formed in an annular shape that protrudes outward in the radial direction and extends around the circumference in the circumferential direction.
  • the engagement protrusion 26f is provided on the proximal end side with respect to the engagement claw 26a.
  • the engaging protrusion 26f may be provided on the distal end cylindrical portion 16d.
  • the base end face 26 g of the fixing member 26 is close to or in contact with the cylindrical body 16. Specifically, the base end face 26g of the fixing member 26 is close to or in contact with the front end face of the shoulder portion 16c.
  • the proximal end inner peripheral surface 26h of the fixing member 26 is close to or abuts on the outer peripheral surface of the distal end cylindrical portion 16d. Specifically, the inner peripheral surface 26h of the base end portion of the fixing member 26 is close to or in contact with the outer peripheral surface of the backlash prevention convex portion 16g.
  • the tube 15 with a needle includes a connector 30 that can be connected to the distal end cylindrical portion 16 d of the cylindrical body 16, a flexible liquid feeding tube 32 having one end connected to the connector 30, and the other end of the liquid feeding tube 32.
  • a patch portion (not shown) that is connected and can be attached to the patient's skin, and an injection needle (not shown) protruding from the patch portion are provided. The injection needle is punctured into the patient's skin.
  • the administration device 14 connected to the drug solution administration device 12 is not limited to the above-described patch-type tube 15 with a needle.
  • a puncture needle (such as a winged needle) is connected to the tip of the liquid delivery tube 32. May be.
  • the administration device 14 may be a bent needle that can be connected to the distal end cylindrical portion 16d of the cylindrical body 16 without using the liquid feeding tube 32.
  • the bent needle is bent approximately 90 ° downward from the distal end cylindrical portion 16d of the cylindrical body 16, and punctures perpendicularly to the skin as the drug solution administration device 12 is fixed (attached) to the skin. Is done.
  • the connector 30 includes a connector main body 34 that can be fitted into the guide tube portion 22, and a needle tube 36 that is held by the connector main body 34 and can be pierced with the sealing member 24.
  • the connector main body 34 has a needle hub member 38 having a base portion 38a for holding the needle tube 36 so that the needle tip 36b becomes a free end, and protrudes from the base portion 38a so as to surround the outer peripheral surface of the needle tube 36 and is substantially concentric with the needle tube 36.
  • a guide member 40 having a guide receiving cylinder part 40a (protective cylinder part) arranged in a conventional manner.
  • the base portion 38a protrudes from the outer peripheral surface of the needle connection portion 42, the needle connection portion 42 to which the needle tube 36 is connected, the tube connection portion 44 that is provided coaxially with the needle connection portion 42 and to which the liquid feeding tube 32 is connected.
  • the flange portion 46 is provided.
  • the needle connecting portion 42 is formed with a linear needle holding hole 42a for holding the needle tube 36.
  • a rough surface region 42b having a concavo-convex shape (wave shape) is provided. Since the rough surface region 42b is provided, the bonding strength can be improved when the needle tube 36 is bonded to the needle connecting portion 42 with an adhesive.
  • a tapered concave portion 42c whose inner diameter increases toward the proximal end direction is provided.
  • the tapered recess 42c functions as an adhesive reservoir, so that the joining strength can be improved.
  • the tube connecting portion 44 is formed with a linear tube holding hole 44a for holding the liquid feeding tube 32.
  • the tube holding hole 44a has a straight portion 44a1 having a constant inner diameter in the axial direction and a tapered portion 44a2 having an inner diameter increasing in the distal direction. Since the tapered portion 44a2 is provided, it is easy to insert the liquid feeding tube 32 when the liquid feeding tube 32 is inserted into the tube holding hole 44a in the assembly process. Further, when the liquid feeding tube 32 is bonded to the tube connecting portion 44 with an adhesive, the taper portion 44a2 functions as an adhesive reservoir, so that the bonding strength can be improved.
  • the flange portion 46 is formed in an annular shape that protrudes outward in the radial direction from the outer peripheral surface of the needle connection portion 42 and makes one round in the circumferential direction.
  • the flange part 46 is joined to the guide receiving cylinder part 40a by an appropriate joining means (for example, adhesive, ultrasonic welding, etc.).
  • the needle connecting portion 42 described above protrudes in the axial direction from the distal end surface 46 a and the proximal end surface 46 b of the flange portion 46.
  • a positioning convex portion 48 protruding in the proximal direction is provided on the proximal end surface 46 b of the flange portion 46.
  • the positioning convex portion 48 is disposed on a circumference centered on the central axis of the base portion 38a.
  • a plurality of positioning convex portions 48 are provided at intervals in the circumferential direction. For this reason, when the flange part 46 is joined to the guide receiving cylinder part 40a with an adhesive, the adhesive enters between the positioning convex parts 48 adjacent in the circumferential direction, so that the joining strength can be improved.
  • the positioning convex portion 48 may be formed in an annular shape that makes a round in the circumferential direction. When the positioning convex portion 48 is joined to the guide receiving tube portion 40a by ultrasonic welding, the positioning convex portion 48 is preferably formed in an annular shape that makes one round in the circumferential direction.
  • the guide tube portion 40a is a hollow cylindrical member surrounding the needle tube 36 protruding from the base portion 38a, and is joined to the base end surface 46b of the flange portion 46 of the base portion 38a.
  • the guide receiving tube portion 40a includes a cylindrical outer tube portion 50 that can be fitted to the outer peripheral surface of the guide tube portion 22, an annular tip wall 52 joined to the flange portion 46 of the base portion 38a, It has an engaging portion 54 that protrudes from the base portion 38 a along the needle tube 36 and is provided inside the outer tube portion 50 (between the needle tube 36 and the outer tube portion 50) and engageable with the fixing member 26.
  • the inner peripheral surface 50a of the outer cylinder part 50 is formed in a taper shape whose inner diameter increases in the proximal direction.
  • the inner peripheral surface 50a of the outer cylinder part 50 may be formed in a straight shape having a constant inner diameter in the axial direction.
  • a connector side rattle prevention portion 50b is provided at the base end of the outer cylinder portion 50.
  • the connector-side rattle prevention portion 50b is formed in an annular shape that bulges outward in the radial direction and makes one round in the circumferential direction.
  • the distal end wall 52 is a plate-like portion that is continuous with the distal end of the outer cylindrical portion 50 and is perpendicular to the axis of the base portion 38a. As shown in FIG. 7B, an annular positioning recess 56 that is recessed in the proximal direction is provided on the distal end surface of the distal end wall 52. The positioning recess 56 is disposed on a circumference centered on the central axis of the base 38a. A positioning convex portion 48 is fitted into the positioning concave portion 56 and is joined by an appropriate joining means (for example, adhesive, ultrasonic fusion, etc.).
  • an appropriate joining means for example, adhesive, ultrasonic fusion, etc.
  • the positioning concave portion 56 may be provided in the flange portion 46 of the base portion 38a, and the positioning convex portion 48 may be provided in the distal end wall 52 of the guide receiving tube portion 40a.
  • the engaging portion 54 is configured to be able to engage with the fixing member 26 along with the relative displacement in the axial direction with respect to the distal end cylindrical portion 16d when the connector 30 is connected to the distal end cylindrical portion 16d.
  • the engaging portion 54 is configured to be inserted between the distal end cylindrical portion 16d and the guide cylindrical portion 22 and to be engaged with the distal end cylindrical portion 16d.
  • the engaging portion 54 can be engaged with the distal end tubular portion 16 d via the engaging protrusion 26 f of the fixing member 26.
  • the engaging part 54 has a support cylinder part 58 protruding from the base part 38a.
  • the engaging portion 54 is supported by a support cylinder 58 that extends in the proximal direction from the inner end of the distal end wall 52, and extends from the proximal end of the support cylinder 58 in the proximal direction.
  • the engaging portion 54 includes a plurality of engaging arms 54a arranged at intervals in the circumferential direction, and claws provided at the free ends of the engaging arms 54a and projecting inward in the radial direction.
  • the engagement arm 54 a extends from the proximal end of the support cylinder portion 58 in the proximal direction.
  • the engaging arm 54a is configured as an elastic piece that can be elastically deformed in the radial direction.
  • the claw portion 54 b can be engaged with the engagement protrusion 26 f of the fixing member 26.
  • the engaging arm 54a and the claw portion 54b are formed in an arc shape along a circumference centering on the central axis (the needle tube 36) of the base portion 38a.
  • the claw portion 54b is disposed on the distal end side of the proximal end surface of the outer cylinder portion 50 (the proximal end surface of the connector-side rattling prevention portion 50b).
  • the needle tube 36 is a hollow needle tube configured in a straight line and having a lumen 36 a, and the lumen 36 a communicates with the lumen of the liquid feeding tube 32.
  • the needle tube 36 has a portion protruding in the proximal direction from the base portion 38a (needle connection portion 42), and has a sharp needle tip 36b at the end portion on the protruding side.
  • the needle tip 36b may be provided with a bent shape that bends toward the needle center axis.
  • the administration device 14 is not connected to the drug solution administration device 12 in the initial state before use. Therefore, when using the drug solution administration system 10, the administration device 14 is connected to the drug solution administration device 12. Specifically, the connector 30 is connected to the distal end tubular portion 16 d of the tubular body 16.
  • the chemical solution administration device 12 is attached to the patient by attaching it to the patient's skin or attaching it to clothes.
  • an injection needle (not shown) of the administration device 14 is punctured into the patient's skin.
  • the drug solution administration device 12 may be attached to the patient before the puncture of the injection needle into the skin.
  • the chemical liquid administration device 12 receives a predetermined operation start command
  • the gasket is pressed by the pusher mechanism, and the chemical liquid M in the cylindrical body 16 is pushed out by advancing the gasket in the cylindrical body 16.
  • the drug solution M pushed out from the cylindrical body 16 is administered (injected) into the patient's body through the administration device 14 punctured by the patient.
  • connection between the connector 30 and the distal end cylindrical portion 16d of the cylindrical body 16 is performed as follows.
  • the connector 30 is moved toward the housing 18 with the needle tip 36b facing the sealing member 24 of the cylindrical body 16, so that the guide cylindrical portion 22 of the housing 18 is inserted into the guide receiving cylindrical portion 40a of the connector main body 34. Insert. Specifically, as shown in FIG. 8, the connector main body 34 is opposed to the distal end cylindrical portion 16 d and the guide cylindrical portion 22, and the needle tip 36 b is opposed to the sealing member 24 of the cylindrical body 16. By moving 34 to the housing body 20 side, the connection between the connector 30 and the distal end cylindrical portion 16d is started. In this case, since the guide tube portion 22 of the housing 18 and the outer tube portion 50 of the connector 30 serve as a fitting guide, the connector 30 can move straight along the axial direction of the tip tube portion 16d. That is, the inner peripheral surface 50 a of the outer cylindrical portion 50 is slidably supported by the outer peripheral surface 22 a of the guide cylindrical portion 22.
  • the needle tube 36 is punctured into the sealing member 24.
  • the needle tube 36 vertically penetrates the sealing member 24, and the lumen of the needle tube 36 communicates with the drug solution chamber 16 a in the cylindrical body 16.
  • the claw portion 54b of the engaging portion 54 is pushed by the engaging protrusion 26f of the fixing member 26, and the engaging arm 54a bends outward (elasticity). Deform).
  • the drug solution administration system 10 has the following effects.
  • the engagement portion 54 engages with the fixing member 26 by the relative movement of the connector 30 relative to the distal end cylindrical portion 16 d in the axial direction.
  • the connector main body 34 is guided by the guide tube portion 22 provided in the housing 18. Therefore, the needle tube 36 is punctured into the sealing member 24 without rotating with respect to the sealing member 24 and without tilting. For this reason, it is possible to effectively suppress the occurrence of coring in which the needle tube 36 scrapes the sealing member 24 when the connector 30 and the distal end cylinder portion 16d are connected.
  • the connector main body 34 has an outer cylindrical portion 50 surrounding the needle tube 36, and the inner peripheral surface 50 a of the outer cylindrical portion 50 can be fitted to the outer peripheral surface 22 a of the guide cylindrical portion 22. With this configuration, the connector 30 can be more stably guided by the guide tube portion 22 when the connector 30 and the distal end tube portion 16d are connected.
  • the engaging portion 54 is provided inside the outer cylindrical portion 50. With this configuration, the engaging portion between the engaging portion 54 and the fixing member 26 can be covered with the outer cylindrical portion 50, so that the engagement between the engaging portion 54 and the fixing member 26 can be reliably maintained. Become.
  • the engaging portion 54 has a plurality of claw portions 54b arranged in the circumferential direction. With this configuration, the engaging portion 54 can be engaged with the fixing member 26 with an appropriate force, and an engaging structure that cannot be easily detached can be constructed.
  • the engaging portion 54 includes a plurality of engaging arms 54a that are arranged at intervals in the circumferential direction and can be elastically deformed in the radial direction, and a claw portion 54b provided at a free end of each engaging arm 54a.
  • the engaging arm 54a and the claw portion 54b are formed in an arc shape along the circumference centering on the needle tube 36 (FIG. 7A). With this configuration, the engagement force between the engagement portion 54 and the fixing member 26 can be effectively increased.
  • the engaging portion 54 When connecting the connector 30 to the cylindrical body 16, the engaging portion 54 is configured to slide on the outer peripheral surface of the fixing member 26 (FIG. 9). With this configuration, the needle tube 36 is further prevented from being tilted with respect to the sealing member 24 when the connector 30 and the distal end cylindrical portion 16d are connected, so that the occurrence of coring can be more effectively suppressed. .
  • the engaging portion 54 When connecting the connector 30 to the cylindrical body 16, the engaging portion 54 is configured to contact the outer peripheral surface of the fixing member 26 before the needle tip 36 b starts to pierce the sealing member 24 (FIG. 9). .
  • the sealing member 24 is not punctured while the needle tube 36 is tilted, the occurrence of coring can be more effectively suppressed.
  • the housing body 20 has an abutting outer peripheral surface 20a adjacent to the proximal end of the guide tube portion 22, and the protruding end of the guide receiving tube portion 40a of the connector body 34 when the connector 30 and the distal end tube portion 16d are completely connected.
  • the part is configured to contact the housing 18 (FIG. 11).
  • the distal end cylinder part 16d has an outer diameter smaller than the outer diameter of the body part 16b, the cylinder body 16 has a shoulder part 16c that connects the body part 16b and the front end cylinder part 16d, and the fixing member 26 is It has a clamping part 26d for clamping the sealing member 24 between the distal end surface of the distal end cylinder part 16d and a peripheral wall part 26b extending in the proximal direction from the clamping part 26d.
  • the proximal end surface of the peripheral wall portion 26b of the fixing member 26 is close to or in contact with the distal end surface of the shoulder portion 16c (FIG. 2).
  • the front end cylinder part 16d has a backlash prevention convex part 16g that protrudes radially outward from the outer peripheral surface of the front end cylinder part 16d.
  • the base end face 26g of the fixing member 26 is in close proximity to or in contact with the rattle-preventing convex part 16g of the distal end cylindrical part 16d.
  • a positioning convex portion 48 is provided on one of the distal end surfaces of the needle hub member 38 and the guide member 40, and the positioning convex portion 48 is fitted on the other of the distal end surfaces of the needle hub member 38 and the guide member 40.
  • a positioning recess 56 is provided.
  • the outer peripheral portion (sealing base portion 24a) of the sealing member 24 is sandwiched between the distal end surface 16de of the distal end cylindrical portion 16d and the inner end portion of the fixing member 26 (the proximal end surface of the clamping portion 26d) and compressed in the axial direction. Has been. With this configuration, high adhesion of the sealing member 24 can be obtained, so that the desired pressure resistance of the cylindrical body 16 can be easily ensured.
  • the inner peripheral surface of the peripheral wall portion 26b of the fixing member 26 is provided with a locking projection 26e for preventing the sealing member 24 from falling off the fixing member 26 before the fixing member 26 is attached to the distal end cylindrical portion 16d. (FIG. 5B).
  • the sealing member 24 has a tip convex portion 24 b that is inserted into the tip hole portion 26 d 1 of the fixing member 26 and protrudes in the tip direction from the tip of the fixing member 26.
  • the sealing member 24 has a proximal end convex portion 24c that is inserted into the distal end cylindrical portion 16d and compressed radially inward by the inner peripheral surface of the distal end cylindrical portion 16d, the liquid-tightness of the sealing member 24 Can be further improved. Since the base end convex portion 24c is compressed radially inward and a liquid-tight seal is formed between the base end convex portion 24c and the inner peripheral surface of the distal end cylindrical portion 16d, the distal end opening portion 16f is securely inserted. It can be sealed.
  • the sealing member 24 has a distal end convex portion 24b inserted into the distal end hole portion 26d1 and a proximal end convex portion 24c inserted into the distal end cylindrical portion 16d, and the distal end convex portion is in a natural state before elastic deformation.
  • the part 24b and the base end convex part 24c are symmetrical in the axial direction.

Abstract

A liquid medicine administration system (10) is provided with a liquid medicine administration device (12) and an administration instrument (14). The liquid medicine administration device (12) is provided with a housing (18) accommodating a cylinder (16) and having a guide cylinder part (22), a seal member (24), and a fixing member (26) for fixing the seal member (24). A connector (30) of the administration instrument (14) has a connector body (34) capable of fitting with the guide cylinder part (22). The connector body (34) has a guide receiving cylinder part (40a) disposed substantially concentrically with a needle tube (36), and an engaging part (54) capable of engaging with the fixing member (26) in conjunction with displacement thereof relative to a distal-end cylinder part (16d) in an axial direction.

Description

薬液投与システムChemical solution administration system
　本発明は、薬液が充填された薬液容器を有する薬液投与装置と、薬液容器に接続可能なコネクタを有する投与器具とを備えた薬液投与システムに関する。 The present invention relates to a chemical solution administration system including a chemical solution administration device having a chemical solution container filled with a chemical solution, and an administration device having a connector connectable to the chemical solution container.
　従来、薬液容器内に充填した薬液を押し子の押圧作用下に生体内に投与するシリンジポンプ型の薬液投与装置は公知である。この種の薬液投与装置は、バレル型の薬液容器と、薬液容器内の薬液を押し出す押し子機構とを備える。薬液投与装置から患者の体内に薬液を移送する投与器具として、薬液投与装置には、例えば針付きチューブが接続される。 2. Description of the Related Art Conventionally, a syringe pump type chemical solution administration device that administers a chemical solution filled in a chemical solution container into a living body under the action of a pusher is known. This type of chemical solution administration device includes a barrel-type chemical solution container and a pusher mechanism that pushes out the chemical solution in the chemical solution container. For example, a tube with a needle is connected to the drug solution administration device as an administration device for transferring the drug solution from the drug solution administration device into the patient's body.
　薬液投与装置と針付きチューブとの接続構造として、針付きチューブの端部に設けられたコネクタを、螺合によって薬液容器の先端部に接続する構造が知られている（例えば、特許第４７５９６３０号公報参照）。この接続構造では、薬液容器の先端開口部に弾性体からなる封止部材（ゴム栓）が固定されており、コネクタと薬液容器との接続に伴って、当該コネクタに設けられた針が封止部材を貫通する。 As a connection structure between a chemical solution administration device and a tube with a needle, there is known a structure in which a connector provided at an end portion of a tube with a needle is connected to a distal end portion of a chemical solution container by screwing (for example, Japanese Patent No. 4759630). See the official gazette). In this connection structure, a sealing member (rubber plug) made of an elastic body is fixed to the tip opening of the chemical solution container, and the needle provided on the connector is sealed when the connector and the chemical solution container are connected. It penetrates the member.
　上述した従来技術では、コネクタと薬液容器との接続は、コネクタを回して螺合させることにより行われる。このため、針が封止部材を刺通する際に封止部材を削り取るコアリングが発生する恐れがある。 In the prior art described above, the connector and the chemical container are connected by turning and screwing the connector. For this reason, when a needle pierces the sealing member, there is a possibility that coring that scrapes off the sealing member may occur.
　本発明はこのような課題を考慮してなされたものであり、コネクタと薬液容器との接続の際にコアリングの発生を抑制することが可能な薬液投与システムを提供することを目的とする。 The present invention has been made in consideration of such problems, and an object thereof is to provide a chemical solution administration system capable of suppressing the occurrence of coring when the connector and the chemical solution container are connected.
　上記の目的を達成するため、本発明は、薬液を充填可能な薬液容器と、前記薬液容器を収容したハウジングと、を有する薬液投与装置と、前記薬液容器に接続可能なコネクタを有し、前記薬液を患者に送液するための投与器具と、を備えた薬液投与システムであって、前記薬液容器は、内部に前記薬液を充填可能な胴部と、前記胴部から先端方向に突出し、先端に先端開口部が設けられた先端筒部と、を有するバレルと、前記先端開口部を液密に封止する弾性材料からなる封止部材と、前記封止部材を前記先端筒部に固定する固定部材とを備え、前記ハウジングは、前記薬液容器を保持するハウジング本体と、前記ハウジング本体から突出するとともに前記先端筒部の外周面を囲み、前記先端筒部と略同心的に配置されたガイド筒部とを有し、前記コネクタは、前記封止部材を刺通可能な針先を有する針管と、前記針管を保持するコネクタ本体とを有し、前記コネクタ本体は、前記針先が自由端となるように前記針管を保持する基部と、前記基部から前記針管の外周面を囲むように突出するとともに前記針管と略同心的に配置されたガイド受筒部と、前記基部から前記針管に沿って突出するとともに前記針管と前記ガイド受筒部との間に配置され、前記先端筒部に係合可能な係合部と、を有し、前記コネクタを前記薬液容器に接続する際、前記針先が前記封止部材に刺さり始める前に、前記ガイド受筒部の内周面は、前記ガイド筒部の外周面と当接可能であり、前記コネクタを前記薬液容器に接続する際、前記係合部は、前記先端筒部と前記ガイド筒部との間に挿入され、かつ、前記先端筒部と係合するように構成されていることを特徴とする。 In order to achieve the above object, the present invention has a chemical solution container that can be filled with a chemical solution, a chemical solution administration device that includes a housing that contains the chemical solution container, and a connector that can be connected to the chemical solution container, An administration device for delivering a chemical solution to a patient, wherein the chemical solution container includes a barrel part that can be filled with the chemical solution therein, a protruding part from the trunk part in a distal direction, and a distal end A barrel having a tip opening provided on the tip opening, a sealing member made of an elastic material for liquid-tightly sealing the tip opening, and fixing the sealing member to the tip barrel A housing main body for holding the chemical solution container, and a guide that protrudes from the housing main body and surrounds the outer peripheral surface of the tip tube portion, and is disposed substantially concentrically with the tip tube portion. With tube The connector includes a needle tube having a needle point through which the sealing member can be pierced, and a connector body that holds the needle tube, and the connector body has the needle tube so that the needle point is a free end. And a guide receiving tube portion that protrudes from the base portion so as to surround the outer peripheral surface of the needle tube and is disposed substantially concentrically with the needle tube, and protrudes along the needle tube from the base portion and the needle tube. And an engaging portion that is engageable with the tip tube portion, and when the connector is connected to the chemical solution container, the needle tip is the sealing member. Before starting to stab, the inner peripheral surface of the guide tube portion can contact the outer peripheral surface of the guide tube portion, and when the connector is connected to the drug solution container, the engaging portion is Inserted between the tube portion and the guide tube portion, and Characterized in that it is configured to engage the serial distal tube portion.
　上記の構成を備えた薬液投与システムによれば、コネクタと先端筒部との接続時に、コネクタが先端筒部に対して軸方向に相対移動することにより係合部が固定部材に係合するとともに、ハウジングに設けられたガイド筒部によりコネクタ本体がガイドされる。従って、針は、封止部材に対して回転することなく、且つ傾くことなく封止部材に穿刺される。このため、コネクタと先端筒部との接続の際、針が封止部材を削り取るコアリングが発生することを効果的に抑制することができる。 According to the drug solution administration system having the above-described configuration, when the connector is connected to the distal end tubular portion, the engagement portion is engaged with the fixed member by the relative movement of the connector relative to the distal end tubular portion in the axial direction. The main body of the connector is guided by the guide cylinder provided in the housing. Therefore, the needle is punctured into the sealing member without rotating with respect to the sealing member and without tilting. For this reason, it is possible to effectively suppress the occurrence of coring in which the needle scrapes off the sealing member when connecting the connector and the distal end cylindrical portion.
　前記固定部材は、前記固定部材の外周面に、前記係合部と係合する係合突起を有し、前記係合部は、前記固定部材の係合突起を介して前記先端筒部と係合可能であってもよい。 The fixing member has an engaging protrusion that engages with the engaging portion on an outer peripheral surface of the fixing member, and the engaging portion is engaged with the tip tube portion via the engaging protrusion of the fixing member. May be possible.
　この構成により、コネクタと先端筒部との接続時に、ガイド筒部によってコネクタをより安定的にガイドすることが可能となる。 This configuration makes it possible to more stably guide the connector by the guide tube portion when the connector and the tip tube portion are connected.
　前記ガイド受筒部は、前記ガイド受筒部の外周面に、前記コネクタを前記薬液容器に接続する際に前記コネクタを把持するための把持部を有していてもよい。 The guide tube portion may have a grip portion for gripping the connector on the outer peripheral surface of the guide tube portion when the connector is connected to the chemical solution container.
　この構成により、係合部と固定部材との係合部位を外側筒部により覆うことができるため、係合部と固定部材との係合を確実に維持することが可能となる。 With this configuration, the engaging portion between the engaging portion and the fixing member can be covered with the outer cylindrical portion, so that the engagement between the engaging portion and the fixing member can be reliably maintained.
　前記係合部は、周方向に間隔を置いて複数配置されるとともに径方向に弾性変形可能な係合アームと、各前記係合アームの自由端部に設けられ、径方向内側に向かって突出したツメ部とを有していてもよい。 A plurality of the engaging portions are arranged at intervals in the circumferential direction, and are provided at an engaging arm that is elastically deformable in the radial direction, and at a free end portion of each engaging arm, and protrudes inward in the radial direction. You may have a claw part.
　この構成により、係合部が適度な力で固定部材に係合することができ、容易には外れない係合構造とすることができる。 With this configuration, the engagement portion can be engaged with the fixing member with an appropriate force, and an engagement structure that cannot be easily detached can be obtained.
　前記係合部は、前記基部から突出した支持筒部を有し、前記係合アームは、前記支持筒部の基端から基端方向に延出していてもよい。 The engagement portion may include a support tube portion protruding from the base portion, and the engagement arm may extend in a proximal direction from a base end of the support tube portion.
　この構成により、係合させる際に、係合アームが確実に弾性変形しつつ、係合後は、確実に係合状態が維持される。 This configuration ensures that the engagement arm is elastically deformed when engaged, and the engaged state is reliably maintained after engagement.
　前記係合アーム及び前記ツメ部は、前記針管を中心とする円周に沿う円弧状に形成されていてもよい。 The engaging arm and the claw portion may be formed in an arc shape along a circumference centering on the needle tube.
　この構成により、係合部と固定部材との係合力を効果的に高めることができる。 This configuration can effectively increase the engaging force between the engaging portion and the fixing member.
　前記コネクタを前記薬液容器に接続する際、前記係合部は、前記固定部材の外周面上を摺動するように構成されてもよい。 When the connector is connected to the chemical solution container, the engaging portion may be configured to slide on the outer peripheral surface of the fixing member.
　この構成により、コネクタと先端筒部との接続の際、針が封止部材に対して傾くことが一層抑制されるため、コアリングの発生をより効果的に抑制することができる。 With this configuration, when the connector and the distal end cylinder portion are connected, the needle is further prevented from being inclined with respect to the sealing member, so that the generation of coring can be more effectively suppressed.
　前記コネクタを前記薬液容器に接続する際、前記針先が前記封止部材に刺さり始める前に、前記係合部は、前記固定部材の前記外周面に接触するように構成されていてもよい。 When connecting the connector to the chemical solution container, the engaging portion may be configured to contact the outer peripheral surface of the fixing member before the needle tip starts to pierce the sealing member.
　この構成により、針が傾いた状態で封止部材に穿刺されることがないため、コアリングの発生をより効果的に抑制することができる。 With this configuration, since the sealing member is not punctured with the needle tilted, the occurrence of coring can be more effectively suppressed.
　前記ハウジング本体は、前記ガイド筒部の基端に隣接する当接外周面を有し、前記コネクタと前記薬液容器との接続完了状態で、前記コネクタ本体の前記ガイド受筒部の突出端部は、前記ハウジングの前記当接外周面に当接するように構成されていてもよい。 The housing body has an abutting outer peripheral surface adjacent to the proximal end of the guide tube portion, and in a state where the connection between the connector and the chemical solution container is completed, the protruding end portion of the guide receiving tube portion of the connector body is The housing may be configured to contact the contact outer peripheral surface.
　この構成により、コネクタと前記先端筒部との接続後、薬液投与装置の使用中にコネクタとハウジングとの接続部にガタツキが発生することが抑制される。このため、ユーザに不安感を与えることがないとともに、液密性の低下を防止することが可能となる。 This configuration suppresses the occurrence of rattling at the connection between the connector and the housing during use of the drug solution administration device after connection between the connector and the tip tube. For this reason, it is possible to prevent the user from feeling uneasy and to prevent a decrease in liquid tightness.
　前記先端筒部は、前記胴部の外径よりも小さい外径を有し、前記薬液容器は、前記胴部と前記先端筒部とを連結する肩部を有し、前記固定部材は、前記先端筒部の先端面との間で前記封止部材を挟持する挟持部と、前記挟持部から基端方向に延びる周壁部とを有し、前記固定部材の前記周壁部の基端面は、前記肩部の先端面に近接又は当接していてもよい。 The distal end cylinder part has an outer diameter smaller than the outer diameter of the body part, the chemical solution container has a shoulder part that connects the body part and the distal end cylinder part, and the fixing member A clamping portion that clamps the sealing member between the distal end surface of the distal end cylindrical portion and a peripheral wall portion extending in the proximal direction from the clamping portion, and the proximal end surface of the peripheral wall portion of the fixing member is You may adjoin or contact | abut to the front end surface of a shoulder part.
　この構成により、先端筒部に対する固定部材のガタツキが防止されるため、封止部材と先端筒部との密着性を保持することができる。このため、液密性を良好に維持し、薬液の漏れを防止することができる。 This configuration prevents the fixing member from rattling with respect to the tip tube portion, so that the adhesion between the sealing member and the tip tube portion can be maintained. For this reason, liquid-tightness can be maintained satisfactorily and chemical liquid leakage can be prevented.
　前記先端筒部は、前記先端筒部の前記外周面から径方向外側に向かって突出したガタツキ防止凸部を有し、前記固定部材の前記周壁部の内周面は、前記先端筒部の前記ガタツキ防止凸部に近接又は当接していてもよい。 The distal end cylinder part has a rattling-preventing convex part that protrudes radially outward from the outer peripheral surface of the distal end cylinder part, and the inner peripheral surface of the peripheral wall part of the fixing member is the same as that of the distal end cylinder part. You may adjoin or contact | abut the rattle prevention convex part.
　この構成により、先端筒部に対する固定部材のガタツキが防止されるため、封止部材と先端筒部との密着性を保持することができる。このため、液密性を良好に維持し、薬液の漏れを防止することができる。 This configuration prevents the fixing member from rattling with respect to the tip tube portion, so that the adhesion between the sealing member and the tip tube portion can be maintained. For this reason, liquid-tightness can be maintained satisfactorily and chemical liquid leakage can be prevented.
　前記コネクタ本体は、前記針管を保持する前記基部を有する針ハブ部材と、前記ガイド受筒部と前記係合部とを有し、前記針ハブ部材に接合されたガイド部材とを備え、前記針ハブ部材の基端面と前記ガイド部材の先端面の一方には、位置決め用凸部が設けられ、前記針ハブ部材とガイド部材の他方には、前記位置決め用凸部が嵌合した位置決め用凹部が設けられていてもよい。 The connector body includes a needle hub member having the base for holding the needle tube, a guide member having the guide receiving tube portion and the engagement portion, and joined to the needle hub member. A positioning convex portion is provided on one of the proximal end surface of the hub member and the distal end surface of the guide member, and a positioning concave portion in which the positioning convex portion is fitted is provided on the other of the needle hub member and the guide member. It may be provided.
　この構成により、針ハブ部材と把持部とを組み付ける際に、針ハブ部材と把持部との中心位置合わせを容易に行うことができ、組み付け精度を向上させることができる。 With this configuration, when the needle hub member and the grip portion are assembled, the center alignment of the needle hub member and the grip portion can be easily performed, and the assembly accuracy can be improved.
　前記固定部材は、前記先端筒部の先端面との間で前記封止部材を挟持する挟持部を有し、前記封止部材の外周部は、前記先端筒部の前記先端面と前記固定部材の前記挟持部との間に挟まれて軸方向に圧縮されていてもよい。 The fixing member includes a clamping portion that clamps the sealing member between a distal end surface of the distal end cylindrical portion, and an outer peripheral portion of the sealing member includes the distal end surface of the distal end cylindrical portion and the fixing member. It may be pinched | interposed between the said clamping parts, and may be compressed by the axial direction.
　この構成により、封止部材の高い密着性が得られるため、筒体の所望の耐圧性を容易に確保することができる。 Since this structure provides high adhesion of the sealing member, the desired pressure resistance of the cylinder can be easily ensured.
　前記固定部材は、前記先端筒部の先端面との間で前記封止部材を挟持する挟持部と、前記挟持部から基端方向に延びる周壁部とを有し、前記固定部材の前記周壁部の内周面には、前記固定部材が前記先端筒部に取り付けられる前に前記固定部材からの前記封止部材の脱落を阻止するための係止突起が設けられていてもよい。 The fixing member includes a holding portion that holds the sealing member between a front end surface of the front end cylindrical portion, and a peripheral wall portion that extends in a proximal direction from the holding portion, and the peripheral wall portion of the fixing member A locking protrusion for preventing the sealing member from falling off from the fixing member may be provided on the inner peripheral surface of the fixing member before the fixing member is attached to the distal end tubular portion.
　この構成により、組立工程において固定部材を先端筒部に取り付ける際に、固定部材内に封止部材を保持させておくことができる。このため、封止部材及び固定部材を先端筒部に取り付ける組付作業を容易に行うことができる。 With this configuration, the sealing member can be held in the fixing member when the fixing member is attached to the distal end tube portion in the assembly process. For this reason, the assembly | attachment operation | work which attaches a sealing member and a fixing member to a front-end | tip cylinder part can be performed easily.
　前記固定部材は、前記先端筒部の先端面との間で前記封止部材を挟持する挟持部と、前記挟持部の中央部を軸方向に貫通する先端孔部とを有し、前記封止部材は、前記固定部材の前記先端孔部に挿入され、前記固定部材の先端よりも先端方向に突出した先端凸部を有していてもよい。 The fixing member includes a sandwiching portion that sandwiches the sealing member with a distal end surface of the distal end cylindrical portion, and a distal end hole portion that penetrates a central portion of the sandwiching portion in the axial direction, and the sealing member The member may have a tip protrusion that is inserted into the tip hole of the fixing member and protrudes in the tip direction from the tip of the fixing member.
　この構成により、コネクタの接続前に、固定部材から突出した封止部材の表面をアルコール綿等で拭き取りやすい。 This configuration makes it easy to wipe the surface of the sealing member protruding from the fixing member with alcohol cotton or the like before connecting the connector.
　前記封止部材は、前記先端筒部内に挿入され、前記先端筒部の内周面により径方向内側に向かって圧縮された基端凸部を有していてもよい。 The sealing member may have a proximal end convex portion that is inserted into the distal end cylindrical portion and compressed radially inward by the inner peripheral surface of the distal end cylindrical portion.
　この構成により、封止部材による液密性を一層向上させることができる。 This configuration can further improve the liquid tightness of the sealing member.
　前記固定部材は、前記先端筒部の先端面との間で前記封止部材を挟持する挟持部と、前記挟持部の中央部を軸方向に貫通する先端孔部とを有し、前記封止部材は、前記固定部材の前記先端孔部に挿入された先端凸部と、前記先端筒部内に挿入された基端凸部とを有し、弾性変形する前の自然状態で、前記先端凸部及び前記基端凸部は、軸方向に対称形状であってもよい。 The fixing member includes a sandwiching portion that sandwiches the sealing member with a distal end surface of the distal end cylindrical portion, and a distal end hole portion that penetrates a central portion of the sandwiching portion in the axial direction, and the sealing member The member has a distal end convex portion inserted into the distal end hole portion of the fixing member and a proximal end convex portion inserted into the distal end cylindrical portion, and the distal end convex portion is in a natural state before elastic deformation. And the base end convex part may have a symmetrical shape in the axial direction.
　この構成により、組立工程において先端筒部と固定部材との間に封止部材を配置する際に、先端凸部と基端凸部とを識別する必要がないため、簡単に組み付けることができる。 With this configuration, when the sealing member is disposed between the distal end cylindrical portion and the fixing member in the assembly process, it is not necessary to distinguish between the distal end convex portion and the proximal end convex portion, so that the assembly can be easily performed.
　また、本発明は、薬液を充填可能な薬液容器と、前記薬液容器を収容したハウジングと、を有する薬液投与装置に接続可能なコネクタであって、前記薬液容器に設けられた先端筒部の先端開口部を封止する封止部材を刺通可能な針先を有する針管と、前記針管を保持するコネクタ本体とを有し、前記コネクタ本体は、前記針先が自由端となるように前記針管を保持する基部と、前記基部から前記針管の外周面を囲むように突出するとともに前記針管と略同心的に配置されたガイド受筒部と、前記基部から前記針管に沿って突出するとともに前記針管と前記ガイド受筒部との間に配置され、前記薬液容器の前記先端筒部に係合可能な係合部と、を有し、前記コネクタを前記薬液容器に接続する際、前記針先が前記封止部材に刺さり始める前に、前記ガイド受筒部の内周面は、前記ハウジングに設けられたガイド筒部の外周面と当接するように構成されており、前記コネクタを前記薬液容器に接続する際、前記係合部は、前記薬液容器の前記先端筒部と前記ハウジングの前記ガイド筒部との間に挿入され、かつ、前記薬液容器の前記先端筒部と係合するように構成されていることを特徴とする。 Further, the present invention is a connector connectable to a chemical solution administration device having a chemical solution container that can be filled with a chemical solution and a housing that accommodates the chemical solution container, and the distal end of the distal end cylinder portion provided in the chemical solution container A needle tube having a needle tip that can be pierced with a sealing member that seals the opening; and a connector main body that holds the needle tube, and the connector main body includes the needle tube such that the needle tip is a free end. And a guide receiving tube portion that protrudes from the base portion so as to surround the outer peripheral surface of the needle tube and is disposed substantially concentrically with the needle tube, and protrudes along the needle tube from the base portion and the needle tube. And an engaging portion that is engageable with the tip tube portion of the chemical solution container, and when connecting the connector to the chemical solution container, the needle tip is Before starting to pierce the sealing member An inner peripheral surface of the guide receiving tube portion is configured to contact an outer peripheral surface of a guide tube portion provided in the housing, and when the connector is connected to the drug solution container, It is configured to be inserted between the tip tube portion of the chemical solution container and the guide tube portion of the housing and to be engaged with the tip tube portion of the drug solution container.
　また、本発明は、薬液を充填可能な薬液容器であって、前記薬液を患者に送液するための投与器具に設けられたコネクタに接続可能であり、内部に前記薬液を充填可能な胴部と、前記胴部から先端方向に突出し、先端に先端開口部が設けられた先端筒部と、を有するバレルと、前記先端開口部を液密に封止する弾性材料からなる封止部材と、前記封止部材を前記先端筒部に固定する固定部材とを備え、前記固定部材は、前記先端筒部の先端面との間で前記封止部材を挟持する挟持部と、前記挟持部の中央を軸方向に貫通する先端孔部とを有し、前記封止部材は、前記固定部材の前記先端孔部に挿入され、前記固定部材の先端よりも先端方向に突出した先端凸部を有することを特徴とする。 Further, the present invention is a chemical container that can be filled with a chemical solution, and can be connected to a connector provided in an administration device for feeding the chemical solution to a patient, and a trunk portion that can be filled with the chemical solution inside And a barrel having a tip tube portion protruding in the tip direction from the body portion and provided with a tip opening at the tip, and a sealing member made of an elastic material that seals the tip opening in a liquid-tight manner, A fixing member that fixes the sealing member to the distal end cylindrical portion, and the fixing member sandwiches the sealing member between the distal end surface of the distal end cylindrical portion and the center of the clamping portion. The sealing member has a tip convex portion that is inserted into the tip hole portion of the fixing member and protrudes in the tip direction from the tip of the fixing member. It is characterized by.
　また、本発明は、薬液を充填可能な薬液容器の先端開口部を液密に封止する弾性材料からなる封止部材であって、前記薬液容器は、内部に前記薬液を充填可能な胴部と、前記胴部から先端方向に突出し、先端に前記先端開口部が設けられた先端筒部と、を有するバレルと、前記先端筒部の先端面との間で前記封止部材を挟持する挟持部と、前記挟持部の中央部を軸方向に貫通する先端孔部とを有する固定部材とを備えるものであり、前記固定部材の前記先端孔部に挿入された先端凸部と、前記先端筒部内に挿入された基端凸部とを有し、弾性変形する前の自然状態で、前記先端凸部及び前記基端凸部は、軸方向に対称形状であることを特徴とする。 Further, the present invention is a sealing member made of an elastic material that liquid-tightly seals the tip opening of a chemical solution container that can be filled with a chemical solution, and the chemical solution container includes a barrel portion that can be filled with the chemical solution therein. And sandwiching the sealing member between a barrel having a tip tube portion protruding from the body portion in the tip direction and provided with the tip opening at the tip, and a tip surface of the tip tube portion And a fixing member having a tip hole portion penetrating in the axial direction through a central portion of the clamping portion, a tip convex portion inserted into the tip hole portion of the fixing member, and the tip cylinder And having a base end convex portion inserted into the portion, and in a natural state before elastic deformation, the tip convex portion and the base end convex portion are symmetrical in the axial direction.
　また、本発明は、薬液を充填可能な薬液容器と、前記薬液容器を収容したハウジングと、を有し、前記薬液を患者に送液するための投与器具のコネクタが接続可能な薬液投与装置であって、前記薬液容器は、内部に前記薬液を充填可能な胴部と、前記胴部から先端方向に突出し、先端に先端開口部が設けられた先端筒部と、を有するバレルと、前記先端開口部を液密に封止する弾性材料からなる封止部材と、前記封止部材を前記先端筒部に固定する固定部材とを備え、前記ハウジングは、前記薬液容器を保持するハウジング本体と、前記ハウジング本体から突出するとともに前記先端筒部の外周面を囲み、前記先端筒部と略同心的に配置された保護筒部とを有し、前記固定部材は、前記固定部材の外周面に、前記コネクタに設けられた係合部と係合可能な係合突起を有し、前記固定部材と前記保護筒部との間に、前記コネクタの前記係合部が挿入可能な挿入凹部が設けられていることを特徴とする。 The present invention also provides a chemical solution administration device having a chemical solution container that can be filled with a chemical solution and a housing that accommodates the chemical solution container, to which a connector of an administration device for delivering the chemical solution to a patient can be connected. The chemical solution container includes a barrel having a barrel portion that can be filled with the chemical solution, a distal end cylindrical portion that protrudes from the barrel portion in a distal direction and is provided with a distal end opening at the distal end, and the distal end A sealing member made of an elastic material that seals the opening in a liquid-tight manner, and a fixing member that fixes the sealing member to the distal end tube portion, and the housing includes a housing body that holds the chemical solution container; The outer peripheral surface of the front end cylindrical portion is protruded from the housing main body and has a protective cylindrical portion arranged substantially concentrically with the front end cylindrical portion, and the fixing member is provided on the outer peripheral surface of the fixing member. Engagement provided in the connector And has an engaging engagement projections, between the fixing member and the protecting cylinder unit, the engaging portion of the connector is characterized in that the insertable insertion recess is provided.
　また、本発明は、薬液を充填可能な薬液容器と、前記薬液容器を収容したハウジングと、を有する薬液投与装置と、前記薬液容器に接続可能なコネクタを有し、前記薬液を患者に送液するための投与器具との接続方法であって、内部に前記薬液を充填可能な胴部と、前記胴部から先端方向に突出し、先端に先端開口部が設けられた先端筒部と、を有するバレルと、前記先端開口部を液密に封止する弾性材料からなる封止部材と、前記封止部材を前記先端筒部に固定する固定部材とを備える前記薬液容器と、前記薬液容器を保持するハウジング本体と、前記ハウジング本体から突出するとともに前記先端筒部の外周面を囲み、前記先端筒部と略同心的に配置されたガイド筒部とを有する前記ハウジングと、を準備し、前記封止部材を刺通可能な針先を有する針管と、前記針管を保持するコネクタ本体と、を備え、前記コネクタ本体は、前記針先が自由端となるように前記針管を保持する基部と、前記基部から前記針管の外周面を囲むように突出するとともに前記針管と略同心的に配置されたガイド受筒部と、前記基部から前記針管に沿って突出するとともに前記針管と前記ガイド受筒部との間に配置され、前記先端筒部に係合可能な係合部と、を有する前記コネクタを準備し、前記コネクタの前記針先を前記薬液容器の前記封止部材と対向させた状態で、前記コネクタを前記ハウジングに向かって移動させることにより、前記コネクタ本体の前記ガイド受筒部内に前記ハウジングの前記ガイド筒部を挿入し、前記ガイド受筒部内への前記ガイド筒部の挿入後に、前記針先を前記封止部材に刺し始めるとともに、前記コネクタ本体の前記係合部を前記先端筒部と前記ガイド筒部との間に挿入し、前記針管で前記封止部材を貫通後に、前記係合部と前記先端筒部とを係合させることを特徴とする。 In addition, the present invention includes a chemical solution administration device having a chemical solution container that can be filled with a chemical solution, a housing that houses the chemical solution container, and a connector that can be connected to the chemical solution container, and the chemical solution is sent to a patient. A method for connecting to an administration device, comprising: a barrel portion that can be filled with the drug solution; and a distal end cylindrical portion that projects from the barrel portion in the distal direction and is provided with a distal end opening. The chemical solution container including a barrel, a sealing member made of an elastic material that seals the tip opening in a liquid-tight manner, and a fixing member that fixes the sealing member to the tip tube portion, and holds the chemical solution container And a housing that protrudes from the housing body and surrounds an outer peripheral surface of the tip tube portion and has a guide tube portion that is disposed substantially concentrically with the tip tube portion. Stop member can be pierced A needle tube having a needle tip; and a connector main body for holding the needle tube, wherein the connector main body has a base portion for holding the needle tube so that the needle tip is a free end, and an outer peripheral surface of the needle tube from the base portion. Projecting so as to surround the guide tube and disposed substantially concentrically with the needle tube, and projecting along the needle tube from the base and disposed between the needle tube and the guide tube portion, The connector having an engaging portion engageable with the distal end cylindrical portion is prepared, and the connector is directed toward the housing in a state where the needle tip of the connector is opposed to the sealing member of the chemical solution container. The guide tube portion of the housing is inserted into the guide tube portion of the connector body, and the needle tip is sealed after the guide tube portion is inserted into the guide tube portion. The engaging portion of the connector main body is inserted between the tip tube portion and the guide tube portion and penetrates the sealing member with the needle tube, and then the engagement portion and the tip tube are inserted. It is characterized by engaging the part.
　本発明の薬液投与システムによれば、コネクタと薬液容器との接続の際にコアリングの発生を抑制することが可能となる。 According to the chemical solution administration system of the present invention, it is possible to suppress the occurrence of coring when connecting the connector and the chemical solution container.
本発明の実施形態に係る薬液投与システムの斜視図である。It is a perspective view of the chemical | medical solution administration system which concerns on embodiment of this invention. コネクタと筒体とを接続する前の初期状態の薬液投与システムの断面図である。It is sectional drawing of the chemical | medical solution administration system of the initial state before connecting a connector and a cylinder. 薬液容器を構成する筒体の斜視図である。It is a perspective view of the cylinder which comprises a chemical | medical solution container. 封止部材の斜視図である。It is a perspective view of a sealing member. 図５Ａは、固定部材の外観斜視図であり、図５Ｂは、固定部材の断面斜視図である。FIG. 5A is an external perspective view of the fixing member, and FIG. 5B is a cross-sectional perspective view of the fixing member. 図６Ａは、針ハブ部材及び針管の外観斜視図であり、図６Ｂは、針ハブ部材及び針管の断面斜視図である。6A is an external perspective view of the needle hub member and the needle tube, and FIG. 6B is a cross-sectional perspective view of the needle hub member and the needle tube. 図７Ａは、ガイド部材の外観斜視図であり、図７Ｂは、ガイド部材の別の角度からの外観斜視図である。FIG. 7A is an external perspective view of a guide member, and FIG. 7B is an external perspective view of the guide member from another angle. コネクタと筒体との接続を開始する際の薬液投与システムの断面図である。It is sectional drawing of the chemical | medical solution administration system at the time of starting the connection of a connector and a cylinder. 封止部材への針管の穿刺を開始する際の薬液投与システムの断面図である。It is sectional drawing of the chemical | medical solution administration system at the time of starting the puncture of the needle tube to a sealing member. 係合部のツメ部が固定部材の係合突起への係合を開始する際の薬液投与システムの断面図である。It is sectional drawing of the chemical | medical solution administration system at the time of the nail | claw part of an engaging part starting engagement to the engaging protrusion of a fixing member. コネクタと筒体との接続が完了した状態の薬液投与システムの断面図である。It is sectional drawing of the chemical | medical solution administration system of the state which the connection of a connector and a cylinder completed.
　以下、本発明に係る薬液投与システムについて好適な実施形態を挙げ、添付の図面を参照しながら説明する。 Hereinafter, preferred embodiments of the drug solution administration system according to the present invention will be described with reference to the accompanying drawings.
　図１に示す本実施形態に係る薬液投与システム１０は、薬液Ｍを生体内に投与するために使用される。薬液投与システム１０は、薬液Ｍを充填可能な薬液容器を構成する筒体１６（バレル）と、筒体１６を収容したハウジング１８とを有する薬液投与装置１２と、筒体１６に接続可能なコネクタ３０を有する投与器具１４とを備える。本実施形態では、製品提供状態で予め薬液Ｍが筒体１６内に充填されている。 1 is used to administer the medicinal solution M into the living body. The drug solution administration system 10 includes a drug body 12 (barrel) that forms a drug solution container that can be filled with a drug solution M, a drug solution administration device 12 that includes a housing 18 that houses the tube body 16, and a connector that can be connected to the cylinder body 16. 30 and an administration device 14 having 30. In the present embodiment, the drug solution M is filled in the cylinder 16 in advance in the product provision state.
　薬液投与装置１２は、筒体１６内に充填された薬液Ｍを押し子機構の押圧作用下に比較的長い時間（例えば、数分～数時間程度）をかけて持続的に生体内に投与する。薬液投与装置１２は、薬液Ｍを間欠的に生体内に投与してもよい。薬液Ｍとしては、例えば、タンパク質製剤、麻薬性鎮痛薬、利尿薬等が挙げられる。 The medicinal solution administration device 12 continuously administers the medicinal solution M filled in the cylinder 16 into the living body over a relatively long time (for example, several minutes to several hours) under the pressing action of the pusher mechanism. . The chemical solution administration device 12 may intermittently administer the chemical solution M into the living body. Examples of the drug solution M include protein preparations, narcotic analgesics, diuretics and the like.
　図１に示すように、薬液投与装置１２の使用時において、薬液投与装置１２には投与器具１４として例えばパッチ式の針付きチューブ１５が接続され、筒体１６から吐出された薬液Ｍが針付きチューブ１５を介して患者の体内に注入される。 As shown in FIG. 1, when using the drug solution administration device 12, for example, a patch-type needle-attached tube 15 is connected to the drug solution administration device 12 as the administration device 14, and the drug solution M discharged from the cylindrical body 16 has a needle. It is injected into the patient's body through the tube 15.
　詳細は図示しないが、薬液投与装置１２は、さらに、筒体１６内に摺動可能に配置されたガスケットと、ガスケットに接続された押し子機構と、押し子機構を駆動する駆動部と、薬液投与装置１２の動作に必要な電力を供給する電池と、駆動部を制御する制御部とを備える。押し子機構、駆動部、電池及び制御部は、ハウジング１８内に収容されている。 Although not shown in detail, the drug solution administration device 12 further includes a gasket slidably disposed in the cylinder body 16, a pusher mechanism connected to the gasket, a drive unit that drives the pusher mechanism, and a drug solution. A battery that supplies power necessary for the operation of the administration device 12 and a control unit that controls the drive unit are provided. The pusher mechanism, the drive unit, the battery, and the control unit are accommodated in the housing 18.
　図３において、筒体１６は、内部に薬液室１６ａを有する中空円筒状に形成されている。具体的に、筒体１６は、その軸方向に内径及び外径が一定の胴部１６ｂと、胴部１６ｂの先端から先端方向に向かって内径及び外径がテーパ状に縮径する肩部１６ｃと、肩部１６ｃから先端方向に突出した先端筒部１６ｄとを有する。 In FIG. 3, the cylindrical body 16 is formed in a hollow cylindrical shape having a chemical solution chamber 16a therein. Specifically, the cylindrical body 16 includes a body portion 16b having a constant inner diameter and outer diameter in the axial direction, and a shoulder portion 16c whose inner diameter and outer diameter are tapered from the distal end of the body portion 16b toward the distal end. And a tip tube portion 16d protruding in the tip direction from the shoulder portion 16c.
　胴部１６ｂの基端には基端開口１６ｅが形成されている。先端筒部１６ｄには、薬液室１６ａと連通する先端開口部１６ｆが形成されている。薬液Ｍは筒体１６内に予め充填されている。 A proximal end opening 16e is formed at the proximal end of the barrel portion 16b. A distal end opening portion 16f communicating with the chemical solution chamber 16a is formed in the distal end cylindrical portion 16d. The chemical solution M is filled in the cylindrical body 16 in advance.
　先端筒部１６ｄの基端部外周には、後述する固定部材２６のガタツキを防止するガタツキ防止凸部１６ｇが設けられている。ガタツキ防止凸部１６ｇは、径方向外方に膨出し且つ周方向に一周延在する環状に形成されている。ガタツキ防止凸部１６ｇの基端は、肩部１６ｃの先端に連なっている。 A backlash prevention convex portion 16g for preventing backlash of the fixing member 26 described later is provided on the outer periphery of the base end portion of the distal end cylindrical portion 16d. The rattling prevention convex portion 16g is formed in an annular shape that bulges outward in the radial direction and extends one round in the circumferential direction. The base end of the rattling prevention convex part 16g is continued to the front end of the shoulder part 16c.
　図２に示すように、先端筒部１６ｄの外周部において、ガタツキ防止凸部１６ｇよりも先端側（先端筒部１６ｄの先端面とガタツキ防止凸部１６ｇとの間）には、固定部材２６の係合ツメ２６ａが係合する係合凸部１６ｈが設けられている。係合凸部１６ｈは、径方向外方に突出し且つ周方向に一周延在する環状に形成されている。係合凸部１６ｈは、係合ツメ２６ａが係止される係止面１６ｈ１と、係止面１６ｈ１よりも先端側に形成されるとともに先端方向に向かって縮径する傾斜面１６ｈ２とを有する。 As shown in FIG. 2, at the outer peripheral portion of the tip cylindrical portion 16d, the fixing member 26 is located on the tip side (between the tip surface of the tip cylindrical portion 16d and the rattling prevention convex portion 16g) with respect to the rattle preventing convex portion 16g. An engagement convex portion 16h that engages with the engagement claw 26a is provided. The engaging convex portion 16h is formed in an annular shape protruding outward in the radial direction and extending once in the circumferential direction. The engaging convex portion 16h has a locking surface 16h1 to which the engaging claw 26a is locked, and an inclined surface 16h2 that is formed on the distal end side with respect to the locking surface 16h1 and is reduced in diameter toward the distal direction.
　ハウジング１８は、筒体１６を保持するハウジング本体２０と、ハウジング本体２０から突出するとともに先端筒部１６ｄの外周面を囲み、先端筒部１６ｄと略同心的に配置されたガイド筒部２２とを有する。上述した押し子機構、駆動部、電池及び制御部は、ハウジング本体２０内に収容されている。図１及び図２において、ガイド筒部２２は、ハウジング本体２０と一体成形されている。なお、ガイド筒部２２は、ハウジング本体２０とは別部品として製作され、ハウジング本体２０に固定された部材であってもよい。 The housing 18 includes a housing main body 20 that holds the cylindrical body 16, and a guide cylindrical portion 22 that protrudes from the housing main body 20, surrounds the outer peripheral surface of the distal end cylindrical portion 16d, and is disposed substantially concentrically with the distal end cylindrical portion 16d. Have. The pusher mechanism, the drive unit, the battery, and the control unit described above are accommodated in the housing body 20. 1 and 2, the guide tube portion 22 is integrally formed with the housing body 20. The guide tube portion 22 may be a member manufactured as a separate component from the housing body 20 and fixed to the housing body 20.
　ガイド筒部２２は、中空円筒形に形成されており、先端筒部１６ｄと同心状に配置されている。図２において、ガイド筒部２２の外周面２２ａは、外径が先端方向に向かって減少するテーパ状である。なお、ガイド筒部２２の外周面２２ａは、外径が軸方向に一定のストレート形状であってもよい。ガイド筒部２２の先端面２２ｂは、先端筒部１６ｄの先端面よりも先端側に位置する。 The guide tube portion 22 is formed in a hollow cylindrical shape and is arranged concentrically with the tip tube portion 16d. In FIG. 2, the outer peripheral surface 22a of the guide cylinder part 22 is a taper shape in which an outer diameter reduces toward a front-end | tip direction. The outer peripheral surface 22a of the guide tube portion 22 may have a straight shape with an outer diameter constant in the axial direction. The distal end surface 22b of the guide cylinder portion 22 is located on the distal end side with respect to the distal end surface of the distal end cylinder portion 16d.
　図１において、ハウジング１８は上面１８ａと底面１８ｂを有する。薬液投与装置１２は、例えば、患者の皮膚に貼り付けて使用するパッチタイプとして構成され得る。このようなパッチタイプの場合、ハウジング１８の底面１８ｂには、皮膚に貼着可能なシート状の貼着部（粘着部）が設けられる。薬液投与装置１２の初期状態で貼着部の貼着面には剥離可能な保護シートが貼り付けられる。 In FIG. 1, the housing 18 has a top surface 18a and a bottom surface 18b. The drug solution administration device 12 may be configured as a patch type that is used by being attached to the skin of a patient, for example. In the case of such a patch type, the bottom surface 18b of the housing 18 is provided with a sheet-like sticking part (adhesive part) that can be stuck to the skin. In the initial state of the chemical liquid administration device 12, a peelable protective sheet is stuck on the sticking surface of the sticking part.
　なお、薬液投与装置１２は、ハウジング１８の底面１８ｂにフックやクリップ等の装着具が設けられ、患者の衣服（例えば、ズボンのウエスト部分等）に引っ掛ける等して取り付けるタイプとして構成されてもよい。また、薬液Ｍが充填された筒体１６と、筒体１６内に摺動可能に配置されたガスケットと、押し子機構は、予め組み合わさっており、使用時にハウジング１８に挿入される形態でもよい。この場合、押し子機構を筒体１６に装着するための装着部が、押し子機構及び筒体１６に設けられていることが好ましい。 The medicinal solution administration device 12 may be configured as a type in which an attachment such as a hook or a clip is provided on the bottom surface 18b of the housing 18 and attached to a patient's clothes (for example, a waist portion of trousers). . Further, the cylindrical body 16 filled with the chemical M, the gasket slidably disposed in the cylindrical body 16, and the pusher mechanism are combined in advance and may be inserted into the housing 18 at the time of use. . In this case, it is preferable that a mounting portion for mounting the pusher mechanism on the cylinder body 16 is provided in the pusher mechanism and the cylinder body 16.
　図１及び図２に示すように、薬液投与装置１２は、さらに、筒体１６の先端開口部１６ｆを液密に封止する弾性材料からなる封止部材２４と、筒体１６の先端開口部１６ｆが設けられた先端筒部１６ｄに封止部材２４を固定する固定部材２６とを備える。 As shown in FIGS. 1 and 2, the medicinal solution administration device 12 further includes a sealing member 24 made of an elastic material that seals the distal end opening 16 f of the cylindrical body 16 in a liquid-tight manner, and a distal end opening of the cylindrical body 16. A fixing member 26 that fixes the sealing member 24 to the distal end cylindrical portion 16d provided with 16f is provided.
　封止部材２４は、ゴム材やエラストマー材等の弾性樹脂材料からなり、先端筒部１６ｄの先端面１６ｄｅと密着することにより、先端開口部１６ｆを液密に封止する栓体である。図２及び図４に示すように、封止部材２４は、厚さ方向の中央部を構成する封止基部２４ａと、封止基部２４ａの先端面から先端方向に突出した先端凸部２４ｂと、封止基部２４ａの基端面から基端方向に突出した基端凸部２４ｃとを有する。 The sealing member 24 is made of an elastic resin material such as a rubber material or an elastomer material, and is a plug that seals the tip opening 16f in a liquid-tight manner by being in close contact with the tip surface 16de of the tip tube portion 16d. As shown in FIGS. 2 and 4, the sealing member 24 includes a sealing base portion 24a that forms a central portion in the thickness direction, a tip convex portion 24b that protrudes in the tip direction from the tip surface of the sealing base portion 24a, And a base end convex portion 24c protruding in the base end direction from the base end surface of the sealing base portion 24a.
　封止基部２４ａ、先端凸部２４ｂ及び基端凸部２４ｃの軸方向に垂直な断面形状は、いずれも円形である。先端凸部２４ｂ及び基端凸部２４ｃの外径は、封止基部２４ａの外径よりも小さい。 The cross-sectional shapes perpendicular to the axial direction of the sealing base 24a, the tip convex portion 24b, and the base end convex portion 24c are all circular. The outer diameters of the tip convex part 24b and the base end convex part 24c are smaller than the outer diameter of the sealing base part 24a.
　図２において、先端凸部２４ｂは、固定部材２６の先端よりも先端方向に突出している。封止部材２４の外周部（封止基部２４ａの外周部）は、先端筒部１６ｄの先端面と固定部材２６の先端部内面（後述する挟持部２６ｄの基端面）との間に挟まれて軸方向に圧縮されている。このため、封止基部２４ａの外周部の先端面２４ａ１は、挟持部２６ｄの基端面に液密に密着している。封止基部２４ａの外周部の基端面２４ａ２は、先端筒部１６ｄの先端面に液密に密着している。 In FIG. 2, the tip protrusion 24 b protrudes in the tip direction from the tip of the fixing member 26. The outer peripheral portion of the sealing member 24 (the outer peripheral portion of the sealing base portion 24a) is sandwiched between the distal end surface of the distal end cylindrical portion 16d and the inner end surface of the fixing member 26 (the proximal end surface of a clamping portion 26d described later). It is compressed in the axial direction. For this reason, the front end surface 24a1 of the outer peripheral part of the sealing base 24a is in liquid-tight contact with the base end surface of the clamping part 26d. The proximal end surface 24a2 of the outer peripheral portion of the sealing base portion 24a is in liquid-tight contact with the distal end surface of the distal end cylindrical portion 16d.
　弾性変形する前の自然状態で、先端凸部２４ｂ及び基端凸部２４ｃは、軸方向に対称形状である。すなわち、先端凸部２４ｂ及び基端凸部２４ｃは、外径及び封止基部２４ａからの突出高さが、互いに同じである。 In the natural state before elastic deformation, the tip convex portion 24b and the base end convex portion 24c are symmetrical in the axial direction. That is, the tip convex part 24b and the base end convex part 24c have the same outer diameter and the protruding height from the sealing base part 24a.
　基端凸部２４ｃの外径は、弾性変形する前の自然状態で先端筒部１６ｄの内径よりも大きいが、図２では基端凸部２４ｃが弾性変形して先端筒部１６ｄの内部に入り込んでいる（嵌合している）。このため、基端凸部２４ｃは、先端筒部１６ｄの内周面に液密に密着している。なお、基端凸部２４ｃは、先端筒部１６ｄの内周面に液密に密着しない形状でもよい。この場合、基端凸部２４ｃの外径は、先端筒部１６ｄの内径よりも小さくなる。また、先端凸部２４ｂの外径は、基端凸部２４ｃと同様に、先端筒部１６ｄの内径よりも小さくなる。 The outer diameter of the base end convex portion 24c is larger than the inner diameter of the distal end cylindrical portion 16d in a natural state before elastic deformation, but in FIG. 2, the proximal end convex portion 24c is elastically deformed and enters the inside of the distal end cylindrical portion 16d. It is out (fitted). For this reason, the base end convex portion 24c is in liquid-tight contact with the inner peripheral surface of the distal end cylindrical portion 16d. Note that the base end convex portion 24c may have a shape that does not liquid-tightly adhere to the inner peripheral surface of the distal end cylindrical portion 16d. In this case, the outer diameter of the base end convex portion 24c is smaller than the inner diameter of the distal end cylindrical portion 16d. Further, the outer diameter of the distal convex portion 24b is smaller than the inner diameter of the distal cylindrical portion 16d, like the proximal convex portion 24c.
　固定部材２６は、先端筒部１６ｄを覆うように先端筒部１６ｄに装着された中空円筒形の部材であり、先端筒部１６ｄとの間に封止部材２４を保持している。図５Ｂに示すように、固定部材２６の内周面には、径方向内方に突出した係合ツメ２６ａが設けられている。係合ツメ２６ａは、周方向に間隔を置いて複数設けられている。固定部材２６の周壁部２６ｂには、係合ツメ２６ａの先端側に隣接する位置にツメ成型用孔部２６ｃが設けられている。ツメ成型用孔部２６ｃが設けられることにより、係合ツメ２６ａを有する固定部材２６を射出成型により容易に製作することができる。 The fixing member 26 is a hollow cylindrical member attached to the distal end cylinder part 16d so as to cover the distal end cylinder part 16d, and holds the sealing member 24 between the distal end cylinder part 16d. As shown in FIG. 5B, an engagement claw 26 a protruding inward in the radial direction is provided on the inner peripheral surface of the fixing member 26. A plurality of engagement claws 26a are provided at intervals in the circumferential direction. On the peripheral wall portion 26b of the fixing member 26, a claw forming hole portion 26c is provided at a position adjacent to the distal end side of the engagement claw 26a. By providing the claw molding hole 26c, the fixing member 26 having the engagement claw 26a can be easily manufactured by injection molding.
　固定部材２６の先端部には、径方向内方に突出した挟持部２６ｄが設けられている。挟持部２６ｄの内周面によって挟持部２６ｄの中央部を軸方向に貫通する先端孔部２６ｄ１が形成されている。固定部材２６の内周面には、径方向内方に膨出した環状の係止突起２６ｅが設けられている。 A pinching portion 26d protruding inward in the radial direction is provided at the distal end portion of the fixing member 26. A tip hole portion 26d1 that penetrates the central portion of the sandwiching portion 26d in the axial direction is formed by the inner peripheral surface of the sandwiching portion 26d. On the inner peripheral surface of the fixing member 26, an annular locking projection 26e bulging inward in the radial direction is provided.
　係止突起２６ｅは、固定部材２６が先端筒部１６ｄに取り付けられる前に固定部材２６からの封止部材２４の脱落を阻止するための突起である。係止突起２６ｅは、挟持部２６ｄと係合ツメ２６ａとの間に形成されている。 The locking protrusion 26e is a protrusion for preventing the sealing member 24 from falling off the fixing member 26 before the fixing member 26 is attached to the distal end cylindrical portion 16d. The locking projection 26e is formed between the clamping portion 26d and the engagement claw 26a.
　固定部材２６の外周部には、コネクタ３０の後述する係合部５４が係合可能な係合突起２６ｆが設けられている。係合突起２６ｆは、径方向外方に突出し且つ周方向に一周延在する環状に形成されている。係合突起２６ｆは、係合ツメ２６ａよりも基端側に設けられている。係合突起２６ｆは、先端筒部１６ｄに設けられていてもよい。 An engaging protrusion 26f is provided on the outer peripheral portion of the fixing member 26 so that an engaging portion 54 (described later) of the connector 30 can be engaged therewith. The engagement protrusion 26f is formed in an annular shape that protrudes outward in the radial direction and extends around the circumference in the circumferential direction. The engagement protrusion 26f is provided on the proximal end side with respect to the engagement claw 26a. The engaging protrusion 26f may be provided on the distal end cylindrical portion 16d.
　図２において、固定部材２６の基端面２６ｇは、筒体１６に近接又は当接している。具体的に、固定部材２６の基端面２６ｇは、肩部１６ｃの先端面に近接又は当接している。固定部材２６の基端部内周面２６ｈは、先端筒部１６ｄの外周面に近接又は当接している。具体的に、固定部材２６の基端部内周面２６ｈは、ガタツキ防止凸部１６ｇの外周面に近接又は当接している。 In FIG. 2, the base end face 26 g of the fixing member 26 is close to or in contact with the cylindrical body 16. Specifically, the base end face 26g of the fixing member 26 is close to or in contact with the front end face of the shoulder portion 16c. The proximal end inner peripheral surface 26h of the fixing member 26 is close to or abuts on the outer peripheral surface of the distal end cylindrical portion 16d. Specifically, the inner peripheral surface 26h of the base end portion of the fixing member 26 is close to or in contact with the outer peripheral surface of the backlash prevention convex portion 16g.
　針付きチューブ１５は、筒体１６の先端筒部１６ｄに接続可能なコネクタ３０と、一端部がコネクタ３０に接続された可撓性を有する送液チューブ３２と、送液チューブ３２の他端に接続され患者の皮膚に貼着可能な図示しないパッチ部と、パッチ部から突出した図示しない注入針とを備える。注入針は患者の皮膚に穿刺される。 The tube 15 with a needle includes a connector 30 that can be connected to the distal end cylindrical portion 16 d of the cylindrical body 16, a flexible liquid feeding tube 32 having one end connected to the connector 30, and the other end of the liquid feeding tube 32. A patch portion (not shown) that is connected and can be attached to the patient's skin, and an injection needle (not shown) protruding from the patch portion are provided. The injection needle is punctured into the patient's skin.
　なお、薬液投与装置１２に接続される投与器具１４は上述したパッチ式の針付きチューブ１５に限られず、例えば、送液チューブ３２の先端に穿刺針（翼状針等）が接続されたものであってもよい。あるいは、投与器具１４は、送液チューブ３２を介さずに筒体１６の先端筒部１６ｄに接続可能な屈曲した針であってもよい。この場合、屈曲した針は、例えば筒体１６の先端筒部１６ｄから下方に略９０°屈曲しており、薬液投与装置１２の皮膚への固定（貼り付け）に伴い皮膚に対して垂直に穿刺される。 The administration device 14 connected to the drug solution administration device 12 is not limited to the above-described patch-type tube 15 with a needle. For example, a puncture needle (such as a winged needle) is connected to the tip of the liquid delivery tube 32. May be. Alternatively, the administration device 14 may be a bent needle that can be connected to the distal end cylindrical portion 16d of the cylindrical body 16 without using the liquid feeding tube 32. In this case, for example, the bent needle is bent approximately 90 ° downward from the distal end cylindrical portion 16d of the cylindrical body 16, and punctures perpendicularly to the skin as the drug solution administration device 12 is fixed (attached) to the skin. Is done.
　図２に示すように、コネクタ３０は、ガイド筒部２２に嵌合可能なコネクタ本体３４と、コネクタ本体３４に保持されるとともに封止部材２４を刺通可能な針管３６とを有する。コネクタ本体３４は、針先３６ｂが自由端となるように針管３６を保持する基部３８ａを有する針ハブ部材３８と、基部３８ａから針管３６の外周面を囲むように突出するとともに針管３６と略同心的に配置されたガイド受筒部４０ａ（保護筒部）を有するガイド部材４０とを備える。基部３８ａは、針管３６が接続された針接続部４２と、針接続部４２と同軸上に設けられるとともに送液チューブ３２が接続されたチューブ接続部４４と、針接続部４２の外周面から突出したフランジ部４６とを備える。 As shown in FIG. 2, the connector 30 includes a connector main body 34 that can be fitted into the guide tube portion 22, and a needle tube 36 that is held by the connector main body 34 and can be pierced with the sealing member 24. The connector main body 34 has a needle hub member 38 having a base portion 38a for holding the needle tube 36 so that the needle tip 36b becomes a free end, and protrudes from the base portion 38a so as to surround the outer peripheral surface of the needle tube 36 and is substantially concentric with the needle tube 36. And a guide member 40 having a guide receiving cylinder part 40a (protective cylinder part) arranged in a conventional manner. The base portion 38a protrudes from the outer peripheral surface of the needle connection portion 42, the needle connection portion 42 to which the needle tube 36 is connected, the tube connection portion 44 that is provided coaxially with the needle connection portion 42 and to which the liquid feeding tube 32 is connected. The flange portion 46 is provided.
　図６Ｂに示すように、針接続部４２には、針管３６を保持する直線状の針保持孔４２ａが形成されている。針保持孔４２ａの基端部内面には、断面が凹凸状（波形状）の粗面領域４２ｂが設けられている。粗面領域４２ｂが設けられているため、針管３６が接着剤で針接続部４２に接合される場合に、接合強度を向上させることができる。 As shown in FIG. 6B, the needle connecting portion 42 is formed with a linear needle holding hole 42a for holding the needle tube 36. On the inner surface of the proximal end portion of the needle holding hole 42a, a rough surface region 42b having a concavo-convex shape (wave shape) is provided. Since the rough surface region 42b is provided, the bonding strength can be improved when the needle tube 36 is bonded to the needle connecting portion 42 with an adhesive.
　針接続部４２の基端部には、基端方向に向かって内径が増大するテーパ状凹部４２ｃが設けられている。針管３６が接着剤で針接続部４２に接合される場合、テーパ状凹部４２ｃが接着剤溜まりとして機能するため、接合強度を向上させることができる。 At the proximal end portion of the needle connecting portion 42, a tapered concave portion 42c whose inner diameter increases toward the proximal end direction is provided. When the needle tube 36 is joined to the needle connecting portion 42 with an adhesive, the tapered recess 42c functions as an adhesive reservoir, so that the joining strength can be improved.
　チューブ接続部４４には、送液チューブ３２を保持する直線状のチューブ保持孔４４ａが形成されている。チューブ保持孔４４ａは、軸方向に内径が一定のストレート部４４ａ１と、先端方向に向かって内径が増大するテーパ部４４ａ２とを有する。テーパ部４４ａ２が設けられているため、組立工程において送液チューブ３２をチューブ保持孔４４ａに挿入する際に、送液チューブ３２を挿入しやすい。また、送液チューブ３２が接着剤でチューブ接続部４４に接合される場合、テーパ部４４ａ２が接着剤溜まりとして機能するため、接合強度を向上させることができる。 The tube connecting portion 44 is formed with a linear tube holding hole 44a for holding the liquid feeding tube 32. The tube holding hole 44a has a straight portion 44a1 having a constant inner diameter in the axial direction and a tapered portion 44a2 having an inner diameter increasing in the distal direction. Since the tapered portion 44a2 is provided, it is easy to insert the liquid feeding tube 32 when the liquid feeding tube 32 is inserted into the tube holding hole 44a in the assembly process. Further, when the liquid feeding tube 32 is bonded to the tube connecting portion 44 with an adhesive, the taper portion 44a2 functions as an adhesive reservoir, so that the bonding strength can be improved.
　フランジ部４６は、針接続部４２の外周面から径方向外方に突出し且つ周方向に一周する円環状に形成されている。フランジ部４６は、適宜の接合手段（例えば、接着剤、超音波溶着等）によりガイド受筒部４０ａに接合されている。上述した針接続部４２は、フランジ部４６の先端面４６ａ及び基端面４６ｂから軸方向に突出している。図６Ａに示すように、フランジ部４６の基端面４６ｂには、基端方向に突出する位置決め用凸部４８が設けられている。位置決め用凸部４８は、基部３８ａの中心軸を中心とする円周上に配置されている。 The flange portion 46 is formed in an annular shape that protrudes outward in the radial direction from the outer peripheral surface of the needle connection portion 42 and makes one round in the circumferential direction. The flange part 46 is joined to the guide receiving cylinder part 40a by an appropriate joining means (for example, adhesive, ultrasonic welding, etc.). The needle connecting portion 42 described above protrudes in the axial direction from the distal end surface 46 a and the proximal end surface 46 b of the flange portion 46. As shown in FIG. 6A, a positioning convex portion 48 protruding in the proximal direction is provided on the proximal end surface 46 b of the flange portion 46. The positioning convex portion 48 is disposed on a circumference centered on the central axis of the base portion 38a.
　図６Ａにおいて、位置決め用凸部４８は、周方向に間隔を置いて複数設けられている。このため、フランジ部４６が接着剤によりガイド受筒部４０ａに接合される場合、周方向に隣接する位置決め用凸部４８間に接着剤が入り込むため、接合強度を向上させることができる。なお、位置決め用凸部４８は、周方向に一周する円環状に形成されてもよい。位置決め用凸部４８が超音波溶着によりガイド受筒部４０ａに接合される場合、接合面積を稼ぐため、位置決め用凸部４８は、周方向に一周する円環状に形成されるのがよい。 6A, a plurality of positioning convex portions 48 are provided at intervals in the circumferential direction. For this reason, when the flange part 46 is joined to the guide receiving cylinder part 40a with an adhesive, the adhesive enters between the positioning convex parts 48 adjacent in the circumferential direction, so that the joining strength can be improved. The positioning convex portion 48 may be formed in an annular shape that makes a round in the circumferential direction. When the positioning convex portion 48 is joined to the guide receiving tube portion 40a by ultrasonic welding, the positioning convex portion 48 is preferably formed in an annular shape that makes one round in the circumferential direction.
　図２に示すガイド受筒部４０ａは、ガイド受筒部４０ａの外周面に、コネクタ３０を筒体１６に接続する際にコネクタ３０を把持するための把持部５０ｃを有する。コネクタ３０を筒体１６に接続する際、針先３６ｂが封止部材２４に刺さり始める前に、ガイド受筒部４０ａの内周面は、ガイド筒部２２の外周面と当接可能である。ガイド受筒部４０ａは、基部３８ａから突出した針管３６を囲む中空円筒状の部材であり、基部３８ａのフランジ部４６の基端面４６ｂに接合されている。具体的に、ガイド受筒部４０ａは、ガイド筒部２２の外周面に嵌合可能な円筒状の外側筒部５０と、基部３８ａのフランジ部４６に接合された円環状の先端壁５２と、基部３８ａから針管３６に沿って突出し、外側筒部５０の内側（針管３６と外側筒部５０との間）に設けられるとともに固定部材２６に係合可能な係合部５４とを有する。 2 has a gripping portion 50c for gripping the connector 30 when the connector 30 is connected to the cylindrical body 16 on the outer peripheral surface of the guide receiving tube portion 40a. When connecting the connector 30 to the cylindrical body 16, the inner peripheral surface of the guide receiving cylinder portion 40 a can come into contact with the outer peripheral surface of the guide cylindrical portion 22 before the needle tip 36 b starts to pierce the sealing member 24. The guide tube portion 40a is a hollow cylindrical member surrounding the needle tube 36 protruding from the base portion 38a, and is joined to the base end surface 46b of the flange portion 46 of the base portion 38a. Specifically, the guide receiving tube portion 40a includes a cylindrical outer tube portion 50 that can be fitted to the outer peripheral surface of the guide tube portion 22, an annular tip wall 52 joined to the flange portion 46 of the base portion 38a, It has an engaging portion 54 that protrudes from the base portion 38 a along the needle tube 36 and is provided inside the outer tube portion 50 (between the needle tube 36 and the outer tube portion 50) and engageable with the fixing member 26.
　外側筒部５０の内周面５０ａは、基端方向に向かって内径が増大するテーパ状に形成されている。なお、外側筒部５０の内周面５０ａは、軸方向に内径が一定のストレート状に形成されていてもよい。外側筒部５０の基端には、コネクタ側ガタツキ防止部５０ｂが設けられている。コネクタ側ガタツキ防止部５０ｂは、径方向外方に膨出し且つ周方向に一周する円環状に形成されている。 The inner peripheral surface 50a of the outer cylinder part 50 is formed in a taper shape whose inner diameter increases in the proximal direction. In addition, the inner peripheral surface 50a of the outer cylinder part 50 may be formed in a straight shape having a constant inner diameter in the axial direction. At the base end of the outer cylinder portion 50, a connector side rattle prevention portion 50b is provided. The connector-side rattle prevention portion 50b is formed in an annular shape that bulges outward in the radial direction and makes one round in the circumferential direction.
　先端壁５２は、外側筒部５０の先端に連なるとともに、基部３８ａの軸に垂直な板状部である。図７Ｂに示すように、先端壁５２の先端面には、基端方向に凹む円環状の位置決め用凹部５６が設けられている。位置決め用凹部５６は、基部３８ａの中心軸を中心とする円周上に配置されている。位置決め用凹部５６には、位置決め用凸部４８が嵌合するとともに、適宜の接合手段（例えば、接着剤、超音波融着等）により接合されている。 The distal end wall 52 is a plate-like portion that is continuous with the distal end of the outer cylindrical portion 50 and is perpendicular to the axis of the base portion 38a. As shown in FIG. 7B, an annular positioning recess 56 that is recessed in the proximal direction is provided on the distal end surface of the distal end wall 52. The positioning recess 56 is disposed on a circumference centered on the central axis of the base 38a. A positioning convex portion 48 is fitted into the positioning concave portion 56 and is joined by an appropriate joining means (for example, adhesive, ultrasonic fusion, etc.).
　なお、上記の構成に代えて、位置決め用凹部５６が基部３８ａのフランジ部４６に設けられ、位置決め用凸部４８がガイド受筒部４０ａの先端壁５２に設けられてもよい。 Instead of the above configuration, the positioning concave portion 56 may be provided in the flange portion 46 of the base portion 38a, and the positioning convex portion 48 may be provided in the distal end wall 52 of the guide receiving tube portion 40a.
　係合部５４は、コネクタ３０を先端筒部１６ｄに接続する際に、先端筒部１６ｄに対する軸方向への相対変位に伴って固定部材２６に係合可能に構成されている。コネクタ３０を筒体１６に接続する際、係合部５４は、先端筒部１６ｄとガイド筒部２２との間に挿入され、かつ、先端筒部１６ｄと係合するように構成されている。係合部５４は、固定部材２６の係合突起２６ｆを介して先端筒部１６ｄと係合可能である。係合部５４は、基部３８ａから突出した支持筒部５８を有する。係合部５４は、先端壁５２の内端から基端方向に延出した支持筒部５８により支持され、支持筒部５８の基端から基端方向に延出している。図７Ａに示すように、係合部５４は、周方向に間隔を置いて複数配置された係合アーム５４ａと、各係合アーム５４ａの自由端に設けられるとともに径方向内方に突出したツメ部５４ｂとを有する。係合アーム５４ａは、支持筒部５８の基端から基端方向に延出している。 The engaging portion 54 is configured to be able to engage with the fixing member 26 along with the relative displacement in the axial direction with respect to the distal end cylindrical portion 16d when the connector 30 is connected to the distal end cylindrical portion 16d. When connecting the connector 30 to the cylindrical body 16, the engaging portion 54 is configured to be inserted between the distal end cylindrical portion 16d and the guide cylindrical portion 22 and to be engaged with the distal end cylindrical portion 16d. The engaging portion 54 can be engaged with the distal end tubular portion 16 d via the engaging protrusion 26 f of the fixing member 26. The engaging part 54 has a support cylinder part 58 protruding from the base part 38a. The engaging portion 54 is supported by a support cylinder 58 that extends in the proximal direction from the inner end of the distal end wall 52, and extends from the proximal end of the support cylinder 58 in the proximal direction. As shown in FIG. 7A, the engaging portion 54 includes a plurality of engaging arms 54a arranged at intervals in the circumferential direction, and claws provided at the free ends of the engaging arms 54a and projecting inward in the radial direction. Part 54b. The engagement arm 54 a extends from the proximal end of the support cylinder portion 58 in the proximal direction.
　係合アーム５４ａは、径方向に弾性変形可能な弾性片として構成されている。ツメ部５４ｂは、固定部材２６の係合突起２６ｆに係合可能である。係合アーム５４ａ及びツメ部５４ｂは、基部３８ａの中心軸（針管３６）を中心とする円周に沿う円弧状に形成されている。ツメ部５４ｂは、外側筒部５０の基端面（コネクタ側ガタツキ防止部５０ｂの基端面）よりも先端側に配置されている。 The engaging arm 54a is configured as an elastic piece that can be elastically deformed in the radial direction. The claw portion 54 b can be engaged with the engagement protrusion 26 f of the fixing member 26. The engaging arm 54a and the claw portion 54b are formed in an arc shape along a circumference centering on the central axis (the needle tube 36) of the base portion 38a. The claw portion 54b is disposed on the distal end side of the proximal end surface of the outer cylinder portion 50 (the proximal end surface of the connector-side rattling prevention portion 50b).
　図２に示すように、針管３６は、直線状に構成されるとともに、内腔３６ａを有する中空針管であり、内腔３６ａが送液チューブ３２の内腔と連通している。針管３６は、基部３８ａ（針接続部４２）から基端方向に突出した部分を有するとともに、突出側の端部に鋭利な針先３６ｂを有する。針管３６が封止部材２４を刺通する際に封止部材２４を削り取るコアリングを抑制するため、針先３６ｂには、針中心軸側に曲がる屈曲形状が付けられていてもよい。 As shown in FIG. 2, the needle tube 36 is a hollow needle tube configured in a straight line and having a lumen 36 a, and the lumen 36 a communicates with the lumen of the liquid feeding tube 32. The needle tube 36 has a portion protruding in the proximal direction from the base portion 38a (needle connection portion 42), and has a sharp needle tip 36b at the end portion on the protruding side. In order to suppress coring that scrapes off the sealing member 24 when the needle tube 36 pierces the sealing member 24, the needle tip 36b may be provided with a bent shape that bends toward the needle center axis.
　次に、上記のように構成された薬液投与システム１０の作用を説明する。 Next, the operation of the drug solution administration system 10 configured as described above will be described.
　薬液投与システム１０において、使用前の初期状態では図２に示すように、薬液投与装置１２には投与器具１４が接続されていない。そこで、薬液投与システム１０の使用に際し、薬液投与装置１２には投与器具１４が接続される。具体的には、コネクタ３０が筒体１６の先端筒部１６ｄに接続される。 In the drug solution administration system 10, as shown in FIG. 2, the administration device 14 is not connected to the drug solution administration device 12 in the initial state before use. Therefore, when using the drug solution administration system 10, the administration device 14 is connected to the drug solution administration device 12. Specifically, the connector 30 is connected to the distal end tubular portion 16 d of the tubular body 16.
　そして、薬液投与装置１２は、患者の皮膚に貼り付ける、あるいは衣服に装着する等して、患者に取り付けられる。次に、投与器具１４の図示しない注入針が患者の皮膚に穿刺される。なお、皮膚への注入針の穿刺前に薬液投与装置１２が患者に取り付けられてもよい。 Then, the chemical solution administration device 12 is attached to the patient by attaching it to the patient's skin or attaching it to clothes. Next, an injection needle (not shown) of the administration device 14 is punctured into the patient's skin. Note that the drug solution administration device 12 may be attached to the patient before the puncture of the injection needle into the skin.
　そして、薬液投与装置１２が所定の動作開始指令を受けると、押し子機構によりガスケットが押圧され、筒体１６内でガスケットが前進することにより、筒体１６内の薬液Ｍが押し出される。筒体１６内から押し出された薬液Ｍは、患者に穿刺された投与器具１４を介して患者の体内に投与（注入）される。 Then, when the chemical liquid administration device 12 receives a predetermined operation start command, the gasket is pressed by the pusher mechanism, and the chemical liquid M in the cylindrical body 16 is pushed out by advancing the gasket in the cylindrical body 16. The drug solution M pushed out from the cylindrical body 16 is administered (injected) into the patient's body through the administration device 14 punctured by the patient.
　コネクタ３０と筒体１６の先端筒部１６ｄとの接続は、具体的には、以下のように行われる。 Specifically, the connection between the connector 30 and the distal end cylindrical portion 16d of the cylindrical body 16 is performed as follows.
　針先３６ｂを筒体１６の封止部材２４と対向させた状態で、コネクタ３０をハウジング１８に向かって移動させることにより、コネクタ本体３４のガイド受筒部４０ａ内にハウジング１８のガイド筒部２２を挿入する。具体的には、図８に示すように、コネクタ本体３４を先端筒部１６ｄ及びガイド筒部２２に対向させるとともに針先３６ｂを筒体１６の封止部材２４と対向させた状態で、コネクタ本体３４をハウジング本体２０側へと移動させることにより、コネクタ３０と先端筒部１６ｄとの接続が開始する。この場合、ハウジング１８のガイド筒部２２及びコネクタ３０の外側筒部５０が、嵌合用のガイドとなるため、コネクタ３０は先端筒部１６ｄの軸方向に沿って真直ぐ移動することが可能である。すなわち、外側筒部５０の内周面５０ａが、ガイド筒部２２の外周面２２ａによってスライド支持される。 The connector 30 is moved toward the housing 18 with the needle tip 36b facing the sealing member 24 of the cylindrical body 16, so that the guide cylindrical portion 22 of the housing 18 is inserted into the guide receiving cylindrical portion 40a of the connector main body 34. Insert. Specifically, as shown in FIG. 8, the connector main body 34 is opposed to the distal end cylindrical portion 16 d and the guide cylindrical portion 22, and the needle tip 36 b is opposed to the sealing member 24 of the cylindrical body 16. By moving 34 to the housing body 20 side, the connection between the connector 30 and the distal end cylindrical portion 16d is started. In this case, since the guide tube portion 22 of the housing 18 and the outer tube portion 50 of the connector 30 serve as a fitting guide, the connector 30 can move straight along the axial direction of the tip tube portion 16d. That is, the inner peripheral surface 50 a of the outer cylindrical portion 50 is slidably supported by the outer peripheral surface 22 a of the guide cylindrical portion 22.
　図９に示すように、コネクタ３０をさらにハウジング本体２０側へと移動させると、封止部材２４への針管３６の穿刺が開始するとともに、係合部５４が先端筒部１６ｄとガイド筒部２２との間に挿入される。この場合、封止部材２４への針管３６の穿刺が開始する前（針先３６ｂが封止部材２４に接触する前）に、係合部５４（具体的には、ツメ部５４ｂ）が固定部材２６の外周面に接触する。従って、係合部５４が固定部材２６により支持され始めた後に針管３６が穿刺を開始する。このため、針管３６が、封止部材２４の軸に対して斜めに穿刺されることがない。 As shown in FIG. 9, when the connector 30 is further moved to the housing body 20 side, puncture of the needle tube 36 into the sealing member 24 is started, and the engaging portion 54 is connected to the distal end tubular portion 16d and the guide tubular portion 22. Inserted between. In this case, before the puncture of the needle tube 36 into the sealing member 24 is started (before the needle tip 36b contacts the sealing member 24), the engaging portion 54 (specifically, the claw portion 54b) is the fixing member. 26 is in contact with the outer peripheral surface. Therefore, the needle tube 36 starts puncturing after the engaging portion 54 is supported by the fixing member 26. For this reason, the needle tube 36 is not punctured obliquely with respect to the axis of the sealing member 24.
　図１０に示すように、コネクタ３０をさらにハウジング本体２０側へと移動させると、針管３６が封止部材２４に穿刺される。この結果、針管３６は垂直に封止部材２４を貫通し、針管３６の内腔が筒体１６内の薬液室１６ａと連通する。また、針管３６の封止部材２４への穿刺と並行して、係合部５４のツメ部５４ｂが固定部材２６の係合突起２６ｆに押されて、係合アーム５４ａが外側に撓む（弾性変形する）。 As shown in FIG. 10, when the connector 30 is further moved toward the housing body 20, the needle tube 36 is punctured into the sealing member 24. As a result, the needle tube 36 vertically penetrates the sealing member 24, and the lumen of the needle tube 36 communicates with the drug solution chamber 16 a in the cylindrical body 16. In parallel with the puncture of the sealing member 24 of the needle tube 36, the claw portion 54b of the engaging portion 54 is pushed by the engaging protrusion 26f of the fixing member 26, and the engaging arm 54a bends outward (elasticity). Deform).
　図１１に示すように、針管３６で封止部材２４を貫通後に、コネクタ３０をさらにハウジング本体２０側へと移動させると、係合部５４のツメ部５４ｂが固定部材２６の係合突起２６ｆを乗り越えて径方向内方に弾性復元することで、係合部５４と係合突起２６ｆとの係合が完了する。これにより、コネクタ３０と先端筒部１６ｄとの接続（投与器具１４と薬液投与装置１２との接続）が完了する。コネクタ３０と先端筒部１６ｄとの接続が完了した状態では、コネクタ側ガタツキ防止部５０ｂがハウジング本体２０の外面に当接する。 As shown in FIG. 11, when the connector 30 is further moved to the housing body 20 side after penetrating the sealing member 24 with the needle tube 36, the claw portion 54 b of the engaging portion 54 causes the engaging protrusion 26 f of the fixing member 26 to move. By overcoming and elastically restoring inward in the radial direction, the engagement between the engagement portion 54 and the engagement protrusion 26f is completed. Thereby, the connection (connection between the administration device 14 and the drug solution administration device 12) between the connector 30 and the distal end cylinder portion 16d is completed. In a state where the connection between the connector 30 and the distal end cylindrical portion 16d is completed, the connector-side rattling prevention portion 50b comes into contact with the outer surface of the housing body 20.
　この場合、本実施形態に係る薬液投与システム１０は、以下の効果を奏する。 In this case, the drug solution administration system 10 according to the present embodiment has the following effects.
　薬液投与システム１０によれば、コネクタ３０と先端筒部１６ｄとの接続時に、コネクタ３０が先端筒部１６ｄに対して軸方向に相対移動することにより係合部５４が固定部材２６に係合するとともに、ハウジング１８に設けられたガイド筒部２２によりコネクタ本体３４がガイドされる。従って、針管３６は、封止部材２４に対して回転することなく、且つ傾くことなく封止部材２４に穿刺される。このため、コネクタ３０と先端筒部１６ｄとの接続の際、針管３６が封止部材２４を削り取るコアリングが発生することを効果的に抑制することができる。 According to the medicinal solution administration system 10, when the connector 30 is connected to the distal end cylindrical portion 16 d, the engagement portion 54 engages with the fixing member 26 by the relative movement of the connector 30 relative to the distal end cylindrical portion 16 d in the axial direction. At the same time, the connector main body 34 is guided by the guide tube portion 22 provided in the housing 18. Therefore, the needle tube 36 is punctured into the sealing member 24 without rotating with respect to the sealing member 24 and without tilting. For this reason, it is possible to effectively suppress the occurrence of coring in which the needle tube 36 scrapes the sealing member 24 when the connector 30 and the distal end cylinder portion 16d are connected.
　コネクタ本体３４は、針管３６を囲む外側筒部５０を有し、外側筒部５０の内周面５０ａが、ガイド筒部２２の外周面２２ａに嵌合可能である。この構成により、コネクタ３０と先端筒部１６ｄとの接続時に、ガイド筒部２２によってコネクタ３０をより安定的にガイドすることが可能となる。 The connector main body 34 has an outer cylindrical portion 50 surrounding the needle tube 36, and the inner peripheral surface 50 a of the outer cylindrical portion 50 can be fitted to the outer peripheral surface 22 a of the guide cylindrical portion 22. With this configuration, the connector 30 can be more stably guided by the guide tube portion 22 when the connector 30 and the distal end tube portion 16d are connected.
　係合部５４は、外側筒部５０の内側に設けられている。この構成により、係合部５４と固定部材２６との係合部位を外側筒部５０により覆うことができるため、係合部５４と固定部材２６との係合を確実に維持することが可能となる。 The engaging portion 54 is provided inside the outer cylindrical portion 50. With this configuration, the engaging portion between the engaging portion 54 and the fixing member 26 can be covered with the outer cylindrical portion 50, so that the engagement between the engaging portion 54 and the fixing member 26 can be reliably maintained. Become.
　係合部５４は、周方向に複数配置されたツメ部５４ｂを有する。この構成により、係合部５４が適度な力で固定部材２６に係合することができ、容易には外れない係合構造を構築することができる。 The engaging portion 54 has a plurality of claw portions 54b arranged in the circumferential direction. With this configuration, the engaging portion 54 can be engaged with the fixing member 26 with an appropriate force, and an engaging structure that cannot be easily detached can be constructed.
　係合部５４は、周方向に間隔を置いて複数配置されるとともに径方向に弾性変形可能な係合アーム５４ａと、各係合アーム５４ａの自由端に設けられたツメ部５４ｂとを有する。この構成により、コネクタ３０と先端筒部１６ｄとを接続する際の抵抗（接続抵抗）が低減されるため接続が容易である一方、係合時にはツメ部５４ｂが引っ掛かることで接続後には外れにくい係合構造を構築することができる。 The engaging portion 54 includes a plurality of engaging arms 54a that are arranged at intervals in the circumferential direction and can be elastically deformed in the radial direction, and a claw portion 54b provided at a free end of each engaging arm 54a. With this configuration, the resistance (connection resistance) when connecting the connector 30 and the distal end cylindrical portion 16d is reduced, so that the connection is easy. On the other hand, the claw portion 54b is caught during engagement, so that it is difficult to come off after the connection. A composite structure can be constructed.
　係合アーム５４ａ及びツメ部５４ｂは、針管３６を中心とする円周に沿う円弧状に形成されている（図７Ａ）。この構成により、係合部５４と固定部材２６との係合力を効果的に高めることができる。 The engaging arm 54a and the claw portion 54b are formed in an arc shape along the circumference centering on the needle tube 36 (FIG. 7A). With this configuration, the engagement force between the engagement portion 54 and the fixing member 26 can be effectively increased.
　コネクタ３０を筒体１６に接続する際、係合部５４は、固定部材２６の外周面上を摺動するように構成されている（図９）。この構成により、コネクタ３０と先端筒部１６ｄとの接続の際、針管３６が封止部材２４に対して傾くことが一層抑制されるため、コアリングの発生をより効果的に抑制することができる。 When connecting the connector 30 to the cylindrical body 16, the engaging portion 54 is configured to slide on the outer peripheral surface of the fixing member 26 (FIG. 9). With this configuration, the needle tube 36 is further prevented from being tilted with respect to the sealing member 24 when the connector 30 and the distal end cylindrical portion 16d are connected, so that the occurrence of coring can be more effectively suppressed. .
　コネクタ３０を筒体１６に接続する際、針先３６ｂが封止部材２４に刺さり始める前に、係合部５４は、固定部材２６の外周面に接触するように構成されている（図９）。この構成により、針管３６が傾いた状態で封止部材２４に穿刺されることがないため、コアリングの発生をより効果的に抑制することができる。 When connecting the connector 30 to the cylindrical body 16, the engaging portion 54 is configured to contact the outer peripheral surface of the fixing member 26 before the needle tip 36 b starts to pierce the sealing member 24 (FIG. 9). . With this configuration, since the sealing member 24 is not punctured while the needle tube 36 is tilted, the occurrence of coring can be more effectively suppressed.
　ハウジング本体２０は、ガイド筒部２２の基端に隣接する当接外周面２０ａを有し、コネクタ３０と先端筒部１６ｄとの接続完了状態で、コネクタ本体３４のガイド受筒部４０ａの突出端部は、ハウジング１８に当接するように構成されている（図１１）。この構成により、コネクタ３０と先端筒部１６ｄとの接続後、薬液投与装置１２の使用中にコネクタ３０とハウジング１８との接続部にガタツキが発生することが抑制される。このため、ユーザに不安感を与えることがないとともに、液密性の低下を防止することが可能となる。 The housing body 20 has an abutting outer peripheral surface 20a adjacent to the proximal end of the guide tube portion 22, and the protruding end of the guide receiving tube portion 40a of the connector body 34 when the connector 30 and the distal end tube portion 16d are completely connected. The part is configured to contact the housing 18 (FIG. 11). With this configuration, after the connection between the connector 30 and the distal end cylindrical portion 16d, the occurrence of rattling at the connection portion between the connector 30 and the housing 18 during use of the drug solution administration device 12 is suppressed. For this reason, it is possible to prevent the user from feeling uneasy and to prevent a decrease in liquid tightness.
　先端筒部１６ｄは、胴部１６ｂの外径よりも小さい外径を有し、筒体１６は、胴部１６ｂと先端筒部１６ｄとを連結する肩部１６ｃを有し、固定部材２６は、先端筒部１６ｄの先端面との間で封止部材２４を挟持する挟持部２６ｄと、挟持部２６ｄから基端方向に延びる周壁部２６ｂとを有する。固定部材２６の周壁部２６ｂの基端面は、肩部１６ｃの先端面に近接又は当接している（図２）。この構成により、先端筒部１６ｄに対する固定部材２６のガタツキが防止されるため、封止部材２４と先端筒部１６ｄとの密着性を保持することができる。このため、液密性を良好に維持し、薬液の漏れを防止することができる。 The distal end cylinder part 16d has an outer diameter smaller than the outer diameter of the body part 16b, the cylinder body 16 has a shoulder part 16c that connects the body part 16b and the front end cylinder part 16d, and the fixing member 26 is It has a clamping part 26d for clamping the sealing member 24 between the distal end surface of the distal end cylinder part 16d and a peripheral wall part 26b extending in the proximal direction from the clamping part 26d. The proximal end surface of the peripheral wall portion 26b of the fixing member 26 is close to or in contact with the distal end surface of the shoulder portion 16c (FIG. 2). With this configuration, rattling of the fixing member 26 with respect to the distal end cylindrical portion 16d is prevented, and thus the adhesion between the sealing member 24 and the distal end cylindrical portion 16d can be maintained. For this reason, liquid-tightness can be maintained satisfactorily and chemical liquid leakage can be prevented.
　先端筒部１６ｄは、先端筒部１６ｄの外周面から径方向外側に向かって突出したガタツキ防止凸部１６ｇを有する。固定部材２６の基端面２６ｇは、先端筒部１６ｄのガタツキ防止凸部１６ｇに近接又は当接している。この構成により、先端筒部１６ｄに対する固定部材２６のガタツキが防止されるため、封止部材２４と先端筒部１６ｄとの密着性を保持することができる。このため、液密性を良好に維持し、薬液Ｍの漏れを効果的に防止することができる。 The front end cylinder part 16d has a backlash prevention convex part 16g that protrudes radially outward from the outer peripheral surface of the front end cylinder part 16d. The base end face 26g of the fixing member 26 is in close proximity to or in contact with the rattle-preventing convex part 16g of the distal end cylindrical part 16d. With this configuration, rattling of the fixing member 26 with respect to the distal end cylindrical portion 16d is prevented, and thus the adhesion between the sealing member 24 and the distal end cylindrical portion 16d can be maintained. For this reason, liquid tightness can be maintained satisfactorily and leakage of the chemical M can be effectively prevented.
　針ハブ部材３８とガイド部材４０の先端面の一方には、位置決め用凸部４８が設けられ、針ハブ部材３８とガイド部材４０の先端面の他方には、位置決め用凸部４８が嵌合した位置決め用凹部５６が設けられている。この構成により、基部３８ａとガイド受筒部４０ａとを組み付ける際に、基部３８ａとガイド受筒部４０ａとの中心位置合わせを容易に行うことができ、組み付け精度を向上させることができる。 A positioning convex portion 48 is provided on one of the distal end surfaces of the needle hub member 38 and the guide member 40, and the positioning convex portion 48 is fitted on the other of the distal end surfaces of the needle hub member 38 and the guide member 40. A positioning recess 56 is provided. With this configuration, when the base portion 38a and the guide receiving tube portion 40a are assembled, the center alignment of the base portion 38a and the guide receiving tube portion 40a can be easily performed, and the assembling accuracy can be improved.
　封止部材２４の外周部（封止基部２４ａ）は、先端筒部１６ｄの先端面１６ｄｅと固定部材２６の先端部内面（挟持部２６ｄの基端面）との間に挟まれて軸方向に圧縮されている。この構成により、封止部材２４の高い密着性が得られるため、筒体１６の所望の耐圧性を容易に確保することができる。 The outer peripheral portion (sealing base portion 24a) of the sealing member 24 is sandwiched between the distal end surface 16de of the distal end cylindrical portion 16d and the inner end portion of the fixing member 26 (the proximal end surface of the clamping portion 26d) and compressed in the axial direction. Has been. With this configuration, high adhesion of the sealing member 24 can be obtained, so that the desired pressure resistance of the cylindrical body 16 can be easily ensured.
　固定部材２６の周壁部２６ｂの内周面には、固定部材２６が先端筒部１６ｄに取り付けられる前に固定部材２６からの封止部材２４の脱落を阻止するための係止突起２６ｅが設けられている（図５Ｂ）。この構成により、組立工程において固定部材２６を先端筒部１６ｄに取り付ける際に、固定部材２６内に封止部材２４を保持させておくことができる。このため、封止部材２４及び固定部材２６を先端筒部１６ｄに取り付ける組付作業を容易に行うことができる。 The inner peripheral surface of the peripheral wall portion 26b of the fixing member 26 is provided with a locking projection 26e for preventing the sealing member 24 from falling off the fixing member 26 before the fixing member 26 is attached to the distal end cylindrical portion 16d. (FIG. 5B). With this configuration, the sealing member 24 can be held in the fixing member 26 when the fixing member 26 is attached to the distal end cylindrical portion 16d in the assembly process. For this reason, the assembling work for attaching the sealing member 24 and the fixing member 26 to the distal end cylindrical portion 16d can be easily performed.
　封止部材２４は、固定部材２６の先端孔部２６ｄ１に挿入され、固定部材２６の先端よりも先端方向に突出した先端凸部２４ｂを有する。この構成により、コネクタ３０の接続前に、消毒のために、固定部材２６から突出した封止部材２４の表面（先端凸部２４ｂの先端面）をアルコール綿等で拭き取りやすい。 The sealing member 24 has a tip convex portion 24 b that is inserted into the tip hole portion 26 d 1 of the fixing member 26 and protrudes in the tip direction from the tip of the fixing member 26. With this configuration, before the connector 30 is connected, the surface of the sealing member 24 protruding from the fixing member 26 (the tip surface of the tip convex portion 24b) can be easily wiped off with alcohol cotton or the like for disinfection.
　封止部材２４は、先端筒部１６ｄ内に挿入され、先端筒部１６ｄの内周面により径方向内側に向かって圧縮された基端凸部２４ｃを有するため、封止部材２４による液密性を一層向上させることができる。基端凸部２４ｃが径方向内側に向かって圧縮されて基端凸部２４ｃと先端筒部１６ｄの内周面との間に液密シールが形成されているため、先端開口部１６ｆを確実に封止することができる。 Since the sealing member 24 has a proximal end convex portion 24c that is inserted into the distal end cylindrical portion 16d and compressed radially inward by the inner peripheral surface of the distal end cylindrical portion 16d, the liquid-tightness of the sealing member 24 Can be further improved. Since the base end convex portion 24c is compressed radially inward and a liquid-tight seal is formed between the base end convex portion 24c and the inner peripheral surface of the distal end cylindrical portion 16d, the distal end opening portion 16f is securely inserted. It can be sealed.
　封止部材２４は、先端孔部２６ｄ１に挿入された先端凸部２４ｂと、先端筒部１６ｄ内に挿入された基端凸部２４ｃとを有し、弾性変形する前の自然状態で、先端凸部２４ｂ及び基端凸部２４ｃは、軸方向に対称形状である。この構成により、組立工程において先端筒部１６ｄと固定部材２６との間に封止部材２４を配置する際に、先端凸部２４ｂと基端凸部２４ｃとを識別する必要がないため、簡単に組み付けることができる。 The sealing member 24 has a distal end convex portion 24b inserted into the distal end hole portion 26d1 and a proximal end convex portion 24c inserted into the distal end cylindrical portion 16d, and the distal end convex portion is in a natural state before elastic deformation. The part 24b and the base end convex part 24c are symmetrical in the axial direction. With this configuration, when the sealing member 24 is disposed between the distal end cylindrical portion 16d and the fixing member 26 in the assembly process, it is not necessary to distinguish between the distal end convex portion 24b and the proximal end convex portion 24c. Can be assembled.
　本発明は上述した実施形態に限定されるものではなく、本発明の要旨を逸脱しない範囲において、種々の改変が可能である。 The present invention is not limited to the above-described embodiment, and various modifications can be made without departing from the gist of the present invention.

Claims (22)

  1. 　薬液（Ｍ）を充填可能な薬液容器と、前記薬液容器を収容したハウジング（１８）と、を有する薬液投与装置（１２）と、
    　前記薬液容器に接続可能なコネクタ（３０）を有し、前記薬液（Ｍ）を患者に送液するための投与器具（１４）と、
    　を備えた薬液投与システム（１０）であって、
    　前記薬液容器は、内部に前記薬液（Ｍ）を充填可能な胴部（１６ｂ）と、前記胴部（１６ｂ）から先端方向に突出し、先端に先端開口部（１６ｆ）が設けられた先端筒部（１６ｄ）と、を有するバレル（１６）と、前記先端開口部（１６ｆ）を液密に封止する弾性材料からなる封止部材（２４）と、前記封止部材（２４）を前記先端筒部（１６ｄ）に固定する固定部材（２６）とを備え、
    　前記ハウジング（１８）は、前記薬液容器を保持するハウジング本体（２０）と、前記ハウジング本体（２０）から突出するとともに前記先端筒部（１６ｄ）の外周面を囲み、前記先端筒部（１６ｄ）と略同心的に配置されたガイド筒部（２２）とを有し、
    　前記コネクタ（３０）は、前記封止部材（２４）を刺通可能な針先（３６ｂ）を有する針管（３６）と、前記針管（３６）を保持するコネクタ本体（３４）とを有し、
    　前記コネクタ本体（３４）は、前記針先（３６ｂ）が自由端となるように前記針管（３６）を保持する基部（３８ａ）と、前記基部（３８ａ）から前記針管（３６）の外周面を囲むように突出するとともに前記針管（３６）と略同心的に配置されたガイド受筒部（４０ａ）と、前記基部（３８ａ）から前記針管（３６）に沿って突出するとともに前記針管（３６）と前記ガイド受筒部（４０ａ）との間に配置され、前記先端筒部（１６ｄ）に係合可能な係合部（５４）と、を有し、
    　前記コネクタ（３０）を前記薬液容器に接続する際、前記針先（３６ｂ）が前記封止部材（２４）に刺さり始める前に、前記ガイド受筒部（４０ａ）の内周面は、前記ガイド筒部（２２）の外周面と当接可能であり、
    　前記コネクタ（３０）を前記薬液容器に接続する際、前記係合部（５４）は、前記先端筒部（１６ｄ）と前記ガイド筒部（２２）との間に挿入され、かつ、前記先端筒部（１６ｄ）と係合するように構成されている
    　ことを特徴とする薬液投与システム（１０）。     A drug solution administration device (12) having a drug solution container capable of filling the drug solution (M) and a housing (18) containing the drug solution container;
    An administration device (14) having a connector (30) connectable to the medicinal solution container, and for delivering the medicinal solution (M) to a patient;
    A drug solution administration system (10) comprising:
    The chemical solution container has a barrel portion (16b) that can be filled with the chemical solution (M) therein, and a distal end cylindrical portion that protrudes in the distal direction from the barrel portion (16b) and is provided with a distal end opening (16f) at the distal end. (16d), a barrel (16) having a sealing member (24) made of an elastic material that liquid-tightly seals the tip opening (16f), and the sealing member (24) A fixing member (26) for fixing to the portion (16d),
    The housing (18) protrudes from the housing body (20) holding the chemical solution container and the housing body (20) and surrounds the outer peripheral surface of the tip tube portion (16d), and the tip tube portion (16d) And a guide tube portion (22) arranged substantially concentrically,
    The connector (30) includes a needle tube (36) having a needle tip (36b) that can pierce the sealing member (24), and a connector body (34) that holds the needle tube (36).
    The connector body (34) includes a base (38a) that holds the needle tube (36) so that the needle tip (36b) is a free end, and an outer peripheral surface of the needle tube (36) from the base (38a). A guide receiving tube portion (40a) that protrudes so as to surround and is disposed substantially concentrically with the needle tube (36), and protrudes along the needle tube (36) from the base portion (38a) and the needle tube (36). And an engaging portion (54) disposed between the guide tube portion (40a) and engageable with the tip tube portion (16d),
    When the connector (30) is connected to the chemical container, the inner peripheral surface of the guide receiving tube portion (40a) is formed before the needle tip (36b) starts to pierce the sealing member (24). Can contact the outer peripheral surface of the cylindrical portion (22),
    When the connector (30) is connected to the chemical container, the engaging portion (54) is inserted between the tip tube portion (16d) and the guide tube portion (22), and the tip tube It is comprised so that it may engage with a part (16d). The chemical | medical solution administration system (10) characterized by the above-mentioned.
  2. 　請求項１記載の薬液投与システム（１０）において、
    　前記固定部材（２６）は、前記固定部材（２６）の外周面に、前記係合部（５４）と係合する係合突起（２６ｆ）を有し、
    　前記係合部（５４）は、前記固定部材（２６）の係合突起（２６ｆ）を介して前記先端筒部（１６ｄ）と係合可能である、
    　ことを特徴とする薬液投与システム（１０）。     The medicinal-solution administration system (10) according to claim 1,
    The fixing member (26) has an engaging protrusion (26f) that engages with the engaging portion (54) on an outer peripheral surface of the fixing member (26).
    The engaging portion (54) is engageable with the distal end tubular portion (16d) via an engaging protrusion (26f) of the fixing member (26).
    A drug solution administration system (10) characterized by the above.
  3. 　請求項２記載の薬液投与システム（１０）において、
    　前記ガイド受筒部（４０ａ）は、前記ガイド受筒部（４０ａ）の外周面に、前記コネクタ（３０）を前記薬液容器に接続する際に前記コネクタ（３０）を把持するための把持部を有する、
    　ことを特徴とする薬液投与システム（１０）。     In the medicinal-solution administration system (10) according to claim 2,
    The guide tube portion (40a) has a grip portion for gripping the connector (30) on the outer peripheral surface of the guide tube portion (40a) when the connector (30) is connected to the chemical solution container. Have
    A drug solution administration system (10) characterized by the above.
  4. 　請求項１～３のいずれか１項に記載の薬液投与システム（１０）において、
    　前記係合部（５４）は、周方向に間隔を置いて複数配置されるとともに径方向に弾性変形可能な係合アーム（５４ａ）と、各前記係合アーム（５４ａ）の自由端部に設けられ、径方向内側に向かって突出したツメ部（５４ｂ）とを有する、
    　ことを特徴とする薬液投与システム（１０）。     The drug solution administration system (10) according to any one of claims 1 to 3,
    A plurality of the engaging portions (54) are arranged at intervals in the circumferential direction, and are provided at an engaging arm (54a) that is elastically deformable in the radial direction, and at a free end portion of each engaging arm (54a). A claw portion (54b) protruding radially inward,
    A drug solution administration system (10) characterized by the above.
  5. 　請求項４記載の薬液投与システム（１０）において、
    　前記係合部（５４）は、前記基部（３８ａ）から突出した支持筒部（５８）を有し、
    　前記係合アーム（５４ａ）は、前記支持筒部（５８）の基端から基端方向に延出している、
    　ことを特徴とする薬液投与システム（１０）。     In the medicinal-solution administration system (10) according to claim 4,
    The engagement portion (54) has a support tube portion (58) protruding from the base portion (38a),
    The engagement arm (54a) extends in the proximal direction from the proximal end of the support tube portion (58).
    A drug solution administration system (10) characterized by the above.
  6. 　請求項５記載の薬液投与システム（１０）において、
    　前記係合アーム（５４ａ）及び前記ツメ部（５４ｂ）は、前記針管（３６）を中心とする円周に沿う円弧状に形成されている、
    　ことを特徴とする薬液投与システム（１０）。     In the medicinal-solution administration system (10) according to claim 5,
    The engagement arm (54a) and the claw portion (54b) are formed in an arc shape along a circumference centering on the needle tube (36).
    A drug solution administration system (10) characterized by the above.
  7. 　請求項１～６のいずれか１項に記載の薬液投与システム（１０）において、
    　前記コネクタ（３０）を前記薬液容器に接続する際、前記係合部（５４）は、前記固定部材（２６）の外周面上を摺動するように構成されている、
    　ことを特徴とする薬液投与システム（１０）。     The medicinal solution administration system (10) according to any one of claims 1 to 6,
    When connecting the connector (30) to the chemical solution container, the engaging portion (54) is configured to slide on the outer peripheral surface of the fixing member (26).
    A drug solution administration system (10) characterized by the above.
  8. 　請求項７記載の薬液投与システム（１０）において、
    　前記コネクタ（３０）を前記薬液容器に接続する際、前記針先（３６ｂ）が前記封止部材（２４）に刺さり始める前に、前記係合部（５４）は、前記固定部材（２６）の前記外周面に接触するように構成されている、
    　ことを特徴とする薬液投与システム（１０）。     In the medicinal-solution administration system (10) according to claim 7,
    When the connector (30) is connected to the chemical container, the engaging portion (54) is connected to the fixing member (26) before the needle tip (36b) starts to pierce the sealing member (24). Configured to contact the outer peripheral surface,
    A drug solution administration system (10) characterized by the above.
  9. 　請求項１～８のいずれか１項に記載の薬液投与システム（１０）において、
    　前記ハウジング本体（２０）は、前記ガイド筒部（２２）の基端に隣接する当接外周面（２０ａ）を有し、
    　前記コネクタ（３０）と前記薬液容器との接続完了状態で、前記コネクタ本体（３４）の前記ガイド受筒部（４０ａ）の突出端部は、前記ハウジング（１８）の前記当接外周面（２０ａ）に当接するように構成されている、
    　ことを特徴とする薬液投与システム（１０）。     The medicinal solution administration system (10) according to any one of claims 1 to 8,
    The housing body (20) has a contact outer peripheral surface (20a) adjacent to a proximal end of the guide tube portion (22),
    When the connection between the connector (30) and the chemical solution container is completed, the protruding end portion of the guide receiving tube portion (40a) of the connector body (34) is the contact outer peripheral surface (20a) of the housing (18). Configured to abut)
    A drug solution administration system (10) characterized by the above.
  10. 　請求項１～９のいずれか１項に記載の薬液投与システム（１０）において、
    　前記先端筒部（１６ｄ）は、前記胴部（１６ｂ）の外径よりも小さい外径を有し、
    　前記薬液容器は、前記胴部（１６ｂ）と前記先端筒部（１６ｄ）とを連結する肩部（１６ｃ）を有し、
    　前記固定部材（２６）は、前記先端筒部（１６ｄ）の先端面との間で前記封止部材（２４）を挟持する挟持部（２６ｄ）と、前記挟持部（２６ｄ）から基端方向に延びる周壁部（２６ｂ）とを有し、前記固定部材（２６）の前記周壁部（２６ｂ）の基端面は、前記肩部（１６ｃ）の先端面に近接又は当接している、
    　ことを特徴とする薬液投与システム（１０）。     The medicinal solution administration system (10) according to any one of claims 1 to 9,
    The tip tube portion (16d) has an outer diameter smaller than the outer diameter of the body portion (16b),
    The chemical solution container has a shoulder portion (16c) that connects the body portion (16b) and the tip tube portion (16d),
    The fixing member (26) includes a clamping portion (26d) that clamps the sealing member (24) between the distal end cylinder portion (16d) and a proximal direction from the clamping portion (26d). A peripheral wall portion (26b) extending, and a proximal end surface of the peripheral wall portion (26b) of the fixing member (26) is close to or in contact with a distal end surface of the shoulder portion (16c).
    A drug solution administration system (10) characterized by the above.
  11. 　請求項１～１０のいずれか１項に記載の薬液投与システム（１０）において、
    　前記先端筒部（１６ｄ）は、前記先端筒部（１６ｄ）の前記外周面から径方向外側に向かって突出したガタツキ防止凸部（１６ｇ）を有し、
    　前記固定部材（２６）の周壁部（２６ｂ）の内周面は、前記先端筒部（１６ｄ）の前記ガタツキ防止凸部（１６ｇ）に近接又は当接している、
    　ことを特徴とする薬液投与システム（１０）。     The medicinal solution administration system (10) according to any one of claims 1 to 10,
    The tip cylinder part (16d) has a rattling prevention convex part (16g) projecting radially outward from the outer peripheral surface of the tip cylinder part (16d),
    The inner peripheral surface of the peripheral wall portion (26b) of the fixing member (26) is in close proximity to or in contact with the rattle prevention convex portion (16g) of the tip tube portion (16d).
    A drug solution administration system (10) characterized by the above.
  12. 　請求項１～１１のいずれか１項に記載の薬液投与システム（１０）において、
    　前記コネクタ本体（３４）は、前記針管（３６）を保持する前記基部（３８ａ）を有する針ハブ部材（３８）と、前記ガイド受筒部（４０ａ）と前記係合部（５４）とを有し、前記針ハブ部材（３８）に接合されたガイド部材（４０）とを備え、
    　前記針ハブ部材（３８）の基端面と前記ガイド部材（４０）の先端面の一方には、位置決め用凸部（４８）が設けられ、
    　前記針ハブ部材（３８）とガイド部材（４０）の他方には、前記位置決め用凸部（４８）が嵌合した位置決め用凹部（５６）が設けられている、
    　ことを特徴とする薬液投与システム（１０）。     The medicinal solution administration system (10) according to any one of claims 1 to 11,
    The connector main body (34) includes a needle hub member (38) having the base (38a) for holding the needle tube (36), the guide receiving tube portion (40a), and the engaging portion (54). And a guide member (40) joined to the needle hub member (38),
    On one of the proximal end surface of the needle hub member (38) and the distal end surface of the guide member (40), a positioning convex portion (48) is provided,
    The other of the needle hub member (38) and the guide member (40) is provided with a positioning recess (56) into which the positioning protrusion (48) is fitted.
    A drug solution administration system (10) characterized by the above.
  13. 　請求項１～１２のいずれか１項に記載の薬液投与システム（１０）において、
    　前記固定部材（２６）は、前記先端筒部（１６ｄ）の先端面との間で前記封止部材（２４）を挟持する挟持部（２６ｄ）を有し、
    　前記封止部材（２４）の外周部は、前記先端筒部（１６ｄ）の前記先端面と前記固定部材（２６）の前記挟持部（２６ｄ）との間に挟まれて軸方向に圧縮されている、
    　ことを特徴とする薬液投与システム（１０）。     The medicinal solution administration system (10) according to any one of claims 1 to 12,
    The fixing member (26) has a clamping part (26d) that clamps the sealing member (24) between the distal end surface of the distal end cylinder part (16d),
    The outer peripheral portion of the sealing member (24) is sandwiched between the distal end surface of the distal end cylindrical portion (16d) and the clamping portion (26d) of the fixing member (26) and is compressed in the axial direction. Yes,
    A drug solution administration system (10) characterized by the above.
  14. 　請求項１～１３のいずれか１項に記載の薬液投与システム（１０）において、
    　前記固定部材（２６）は、前記先端筒部（１６ｄ）の先端面との間で前記封止部材（２４）を挟持する挟持部（２６ｄ）と、前記挟持部（２６ｄ）から基端方向に延びる周壁部（２６ｂ）とを有し、
    　前記固定部材（２６）の前記周壁部（２６ｂ）の内周面には、前記固定部材（２６）が前記先端筒部（１６ｄ）に取り付けられる前に前記固定部材（２６）からの前記封止部材（２４）の脱落を阻止するための係止突起（２６ｅ）が設けられている、
    　ことを特徴とする薬液投与システム（１０）。     The medicinal solution administration system (10) according to any one of claims 1 to 13,
    The fixing member (26) includes a clamping portion (26d) that clamps the sealing member (24) between the distal end cylinder portion (16d) and a proximal direction from the clamping portion (26d). A peripheral wall portion (26b) extending,
    On the inner peripheral surface of the peripheral wall portion (26b) of the fixing member (26), the sealing member (26) is sealed from the fixing member (26) before the fixing member (26) is attached to the distal end tubular portion (16d). A locking projection (26e) for preventing the member (24) from falling off is provided.
    A drug solution administration system (10) characterized by the above.
  15. 　請求項１～１４のいずれか１項に記載の薬液投与システム（１０）において、
    　前記固定部材（２６）は、前記先端筒部（１６ｄ）の先端面との間で前記封止部材（２４）を挟持する挟持部（２６ｄ）と、前記挟持部（２６ｄ）の中央部を軸方向に貫通する先端孔部（２６ｄ１）とを有し、
    　前記封止部材（２４）は、前記固定部材（２６）の前記先端孔部（２６ｄ１）に挿入され、前記固定部材（２６）の先端よりも先端方向に突出した先端凸部（２４ｂ）を有する、
    　ことを特徴とする薬液投与システム（１０）。     The medicinal solution administration system (10) according to any one of claims 1 to 14,
    The fixing member (26) has a pinching portion (26d) that holds the sealing member (24) between the tip end surface of the tip cylindrical portion (16d) and a central portion of the pinching portion (26d). A tip hole portion (26d1) penetrating in the direction,
    The sealing member (24) is inserted into the tip hole portion (26d1) of the fixing member (26) and has a tip convex portion (24b) protruding in the tip direction from the tip of the fixing member (26). ,
    A drug solution administration system (10) characterized by the above.
  16. 　請求項１～１５のいずれか１項に記載の薬液投与システム（１０）において、
    　前記封止部材（２４）は、前記先端筒部（１６ｄ）内に挿入され、前記先端筒部（１６ｄ）の内周面により径方向内側に向かって圧縮された基端凸部（２４ｃ）を有する、
    　ことを特徴とする薬液投与システム（１０）。     The medicinal solution administration system (10) according to any one of claims 1 to 15,
    The sealing member (24) has a proximal end convex portion (24c) inserted into the distal end tubular portion (16d) and compressed radially inward by the inner peripheral surface of the distal end tubular portion (16d). Have
    A drug solution administration system (10) characterized by the above.
  17. 　請求項１～１４のいずれか１項に記載の薬液投与システム（１０）において、
    　前記固定部材（２６）は、前記先端筒部（１６ｄ）の先端面との間で前記封止部材（２４）を挟持する挟持部（２６ｄ）と、前記挟持部（２６ｄ）の中央部を軸方向に貫通する先端孔部（２６ｄ１）とを有し、
    　前記封止部材（２４）は、前記固定部材（２６）の前記先端孔部（２６ｄ１）に挿入された先端凸部（２４ｂ）と、前記先端筒部（１６ｄ）内に挿入された基端凸部（２４ｃ）とを有し、
    　弾性変形する前の自然状態で、前記先端凸部（２４ｂ）及び前記基端凸部（２４ｃ）は、軸方向に対称形状である、
    　ことを特徴とする薬液投与システム（１０）。     The medicinal solution administration system (10) according to any one of claims 1 to 14,
    The fixing member (26) has a pinching portion (26d) that holds the sealing member (24) between the tip end surface of the tip cylindrical portion (16d) and a central portion of the pinching portion (26d). A tip hole portion (26d1) penetrating in the direction,
    The sealing member (24) includes a distal end convex portion (24b) inserted into the distal end hole portion (26d1) of the fixing member (26) and a proximal end convex portion inserted into the distal end cylindrical portion (16d). Part (24c),
    In the natural state before elastically deforming, the tip convex portion (24b) and the base end convex portion (24c) are symmetrical in the axial direction.
    A drug solution administration system (10) characterized by the above.
  18. 　薬液（Ｍ）を充填可能な薬液容器と、前記薬液容器を収容したハウジング（１８）と、を有する薬液投与装置（１２）に接続可能なコネクタ（３０）であって、
    　前記薬液容器に設けられた先端筒部（１６ｄ）の先端開口部（１６ｆ）を封止する封止部材（２４）を刺通可能な針先（３６ｂ）を有する針管（３６）と、前記針管（３６）を保持するコネクタ本体（３４）とを有し、
    　前記コネクタ本体（３４）は、前記針先（３６ｂ）が自由端となるように前記針管（３６）を保持する基部（３８ａ）と、前記基部（３８ａ）から前記針管（３６）の外周面を囲むように突出するとともに前記針管（３６）と略同心的に配置されたガイド受筒部（４０ａ）と、前記基部（３８ａ）から前記針管（３６）に沿って突出するとともに前記針管（３６）と前記ガイド受筒部（４０ａ）との間に配置され、前記薬液容器の前記先端筒部（１６ｄ）に係合可能な係合部（５４）と、を有し、
    　前記コネクタ（３０）を前記薬液容器に接続する際、前記針先（３６ｂ）が前記封止部材（２４）に刺さり始める前に、前記ガイド受筒部（４０ａ）の内周面は、前記ハウジング（１８）に設けられたガイド筒部（２２）の外周面と当接するように構成されており、
    　前記コネクタ（３０）を前記薬液容器に接続する際、前記係合部（５４）は、前記薬液容器の前記先端筒部（１６ｄ）と前記ハウジング（１８）の前記ガイド筒部（２２）との間に挿入され、かつ、前記薬液容器の前記先端筒部（１６ｄ）と係合するように構成されている
    　ことを特徴とするコネクタ（３０）。     A connector (30) connectable to a drug solution administration device (12) having a drug solution container capable of filling a drug solution (M) and a housing (18) containing the drug solution container;
    A needle tube (36) having a needle tip (36b) capable of being pierced with a sealing member (24) for sealing a distal end opening (16f) of a distal end cylindrical portion (16d) provided in the chemical liquid container; and the needle tube A connector body (34) for holding (36),
    The connector body (34) includes a base (38a) that holds the needle tube (36) so that the needle tip (36b) is a free end, and an outer peripheral surface of the needle tube (36) from the base (38a). A guide receiving tube portion (40a) that protrudes so as to surround and is disposed substantially concentrically with the needle tube (36), and protrudes along the needle tube (36) from the base portion (38a) and the needle tube (36). An engagement portion (54) disposed between the guide tube portion (40a) and engageable with the tip tube portion (16d) of the chemical solution container,
    When the connector (30) is connected to the chemical solution container, before the needle tip (36b) starts to pierce the sealing member (24), the inner peripheral surface of the guide receiving tube portion (40a) It is comprised so that it may contact | abut with the outer peripheral surface of the guide cylinder part (22) provided in (18),
    When the connector (30) is connected to the chemical solution container, the engaging portion (54) is formed between the tip tube portion (16d) of the drug solution container and the guide tube portion (22) of the housing (18). The connector (30), wherein the connector (30) is configured to be inserted therebetween and to be engaged with the distal end cylindrical portion (16d) of the chemical solution container.
  19. 　薬液（Ｍ）を充填可能な薬液容器であって、
    　前記薬液（Ｍ）を患者に送液するための投与器具（１４）に設けられたコネクタ（３０）に接続可能であり、
    　内部に前記薬液（Ｍ）を充填可能な胴部（１６ｂ）と、前記胴部（１６ｂ）から先端方向に突出し、先端に先端開口部（１６ｆ）が設けられた先端筒部（１６ｄ）と、を有するバレル（１６）と、前記先端開口部（１６ｆ）を液密に封止する弾性材料からなる封止部材（２４）と、前記封止部材（２４）を前記先端筒部（１６ｄ）に固定する固定部材（２６）とを備え、
    　前記固定部材（２６）は、前記先端筒部（１６ｄ）の先端面との間で前記封止部材（２４）を挟持する挟持部（２６ｄ）と、前記挟持部（２６ｄ）の中央を軸方向に貫通する先端孔部（２６ｄ１）とを有し、
    　前記封止部材（２４）は、前記固定部材（２６）の前記先端孔部（２６ｄ１）に挿入され、前記固定部材（２６）の先端よりも先端方向に突出した先端凸部（２４ｂ）を有する、
    　ことを特徴とする薬液容器。     A chemical solution container that can be filled with a chemical solution (M),
    Connectable to a connector (30) provided on an administration device (14) for delivering the medicinal solution (M) to a patient;
    A barrel portion (16b) that can be filled with the chemical liquid (M) therein, a distal end cylindrical portion (16d) that protrudes in the distal direction from the barrel portion (16b) and has a distal end opening (16f) at the distal end; A barrel (16) having a sealing member, a sealing member (24) made of an elastic material for liquid-tightly sealing the tip opening (16f), and the sealing member (24) on the tip tube portion (16d). A fixing member (26) for fixing,
    The fixing member (26) includes a clamping portion (26d) that clamps the sealing member (24) between the distal end surface of the distal end cylindrical portion (16d) and a center of the clamping portion (26d) in the axial direction. A front end hole (26d1) penetrating through
    The sealing member (24) is inserted into the tip hole portion (26d1) of the fixing member (26) and has a tip convex portion (24b) protruding in the tip direction from the tip of the fixing member (26). ,
    A chemical container characterized by that.
  20. 　薬液（Ｍ）を充填可能な薬液容器の先端開口部（１６ｆ）を液密に封止する弾性材料からなる封止部材（２４）であって、
    　前記薬液容器は、内部に前記薬液（Ｍ）を充填可能な胴部（１６ｂ）と、前記胴部（１６ｂ）から先端方向に突出し、先端に前記先端開口部（１６ｆ）が設けられた先端筒部（１６ｄ）と、を有するバレル（１６）と、前記先端筒部（１６ｄ）の先端面との間で前記封止部材（２４）を挟持する挟持部（２６ｄ）と、前記挟持部（２６ｄ）の中央部を軸方向に貫通する先端孔部（２６ｄ１）とを有する固定部材（２６）とを備えるものであり、
    　前記固定部材（２６）の前記先端孔部（２６ｄ１）に挿入された先端凸部（２４ｂ）と、前記先端筒部（１６ｄ）内に挿入された基端凸部（２４ｃ）とを有し、
    　弾性変形する前の自然状態で、前記先端凸部（２４ｂ）及び前記基端凸部（２４ｃ）は、軸方向に対称形状である、
    　ことを特徴とする封止部材（２４）。     A sealing member (24) made of an elastic material that liquid-tightly seals the tip opening (16f) of the chemical liquid container that can be filled with the chemical liquid (M),
    The chemical solution container has a barrel (16b) that can be filled with the chemical (M) therein, a distal end tube that protrudes from the barrel (16b) in the distal direction, and is provided with the distal end opening (16f) at the distal end. A sandwiching portion (26d) for sandwiching the sealing member (24) between a barrel (16) having a portion (16d) and a distal end surface of the distal end tubular portion (16d); and the sandwiching portion (26d) ) And a fixing member (26) having a tip hole portion (26d1) penetrating the central portion in the axial direction,
    A distal end convex portion (24b) inserted into the distal end hole portion (26d1) of the fixing member (26) and a proximal end convex portion (24c) inserted into the distal end cylindrical portion (16d);
    In the natural state before elastically deforming, the tip convex portion (24b) and the base end convex portion (24c) are symmetrical in the axial direction.
    The sealing member (24) characterized by the above-mentioned.
  21. 　薬液（Ｍ）を充填可能な薬液容器と、前記薬液容器を収容したハウジング（１８）と、を有し、前記薬液（Ｍ）を患者に送液するための投与器具（１４）のコネクタ（３０）が接続可能な薬液投与装置（１２）であって、
    　前記薬液容器は、内部に前記薬液（Ｍ）を充填可能な胴部（１６ｂ）と、前記胴部（１６ｂ）から先端方向に突出し、先端に先端開口部（１６ｆ）が設けられた先端筒部（１６ｄ）と、を有するバレル（１６）と、前記先端開口部（１６ｆ）を液密に封止する弾性材料からなる封止部材（２４）と、前記封止部材（２４）を前記先端筒部（１６ｄ）に固定する固定部材（２６）とを備え、
    　前記ハウジング（１８）は、前記薬液容器を保持するハウジング本体（２０）と、前記ハウジング本体（２０）から突出するとともに前記先端筒部（１６ｄ）の外周面を囲み、前記先端筒部（１６ｄ）と略同心的に配置された保護筒部とを有し、
    　前記固定部材（２６）は、前記固定部材（２６）の外周面に、前記コネクタ（３０）に設けられた係合部（５４）と係合可能な係合突起（２６ｆ）を有し、
    　前記固定部材（２６）と前記保護筒部との間に、前記コネクタ（３０）の前記係合部（５４）が挿入可能な挿入凹部が設けられている
    　ことを特徴とする薬液投与装置（１２）。     A connector (30) of an administration device (14) having a drug solution container capable of filling the drug solution (M) and a housing (18) containing the drug solution container and for feeding the drug solution (M) to a patient. ) Is a connectable chemical solution administration device (12),
    The chemical solution container has a barrel portion (16b) that can be filled with the chemical solution (M) therein, and a distal end cylindrical portion that protrudes in the distal direction from the barrel portion (16b) and is provided with a distal end opening (16f) at the distal end. (16d), a barrel (16) having a sealing member (24) made of an elastic material that liquid-tightly seals the tip opening (16f), and the sealing member (24) A fixing member (26) for fixing to the portion (16d),
    The housing (18) protrudes from the housing body (20) holding the chemical solution container and the housing body (20) and surrounds the outer peripheral surface of the tip tube portion (16d), and the tip tube portion (16d) And a protective cylinder arranged substantially concentrically,
    The fixing member (26) has an engaging protrusion (26f) that can engage with an engaging portion (54) provided on the connector (30) on an outer peripheral surface of the fixing member (26).
    An insertion recess into which the engaging portion (54) of the connector (30) can be inserted is provided between the fixing member (26) and the protective cylinder portion (12). ).
  22. 　薬液（Ｍ）を充填可能な薬液容器と、前記薬液容器を収容したハウジング（１８）と、を有する薬液投与装置（１２）と、前記薬液容器に接続可能なコネクタ（３０）を有し、前記薬液（Ｍ）を患者に送液するための投与器具（１４）との接続方法であって、
    　内部に前記薬液（Ｍ）を充填可能な胴部（１６ｂ）と、前記胴部（１６ｂ）から先端方向に突出し、先端に先端開口部（１６ｆ）が設けられた先端筒部（１６ｄ）と、を有するバレル（１６）と、前記先端開口部（１６ｆ）を液密に封止する弾性材料からなる封止部材（２４）と、前記封止部材（２４）を前記先端筒部（１６ｄ）に固定する固定部材（２６）とを備える前記薬液容器と、前記薬液容器を保持するハウジング本体（２０）と、前記ハウジング本体（２０）から突出するとともに前記先端筒部（１６ｄ）の外周面を囲み、前記先端筒部（１６ｄ）と略同心的に配置されたガイド筒部（２２）とを有する前記ハウジング（１８）と、を準備し、
    　前記封止部材（２４）を刺通可能な針先（３６ｂ）を有する針管（３６）と、前記針管（３６）を保持するコネクタ本体（３４）と、を備え、前記コネクタ本体（３４）は、前記針先（３６ｂ）が自由端となるように前記針管（３６）を保持する基部（３８ａ）と、前記基部（３８ａ）から前記針管（３６）の外周面を囲むように突出するとともに前記針管（３６）と略同心的に配置されたガイド受筒部（４０ａ）と、前記基部（３８ａ）から前記針管（３６）に沿って突出するとともに前記針管（３６）と前記ガイド受筒部（４０ａ）との間に配置され、前記先端筒部（１６ｄ）に係合可能な係合部（５４）と、を有する前記コネクタ（３０）を準備し、
    　前記コネクタ（３０）の前記針先（３６ｂ）を前記薬液容器の前記封止部材（２４）と対向させた状態で、前記コネクタ（３０）を前記ハウジング（１８）に向かって移動させることにより、前記コネクタ本体（３４）の前記ガイド受筒部（４０ａ）内に前記ハウジング（１８）の前記ガイド筒部（２２）を挿入し、
    　前記ガイド受筒部（４０ａ）内への前記ガイド筒部（２２）の挿入後に、前記針先（３６ｂ）を前記封止部材（２４）に刺し始めるとともに、前記コネクタ本体（３４）の前記係合部（５４）を前記先端筒部（１６ｄ）と前記ガイド筒部（２２）との間に挿入し、
    　前記針管（３６）で前記封止部材（２４）を貫通後に、前記係合部（５４）と前記先端筒部（１６ｄ）とを係合させる、
    　ことを特徴とする接続方法。     A chemical liquid container (12) having a chemical liquid container capable of filling the chemical liquid (M), a housing (18) containing the chemical liquid container, and a connector (30) connectable to the chemical liquid container, A method of connection with an administration device (14) for delivering a medicinal solution (M) to a patient,
    A barrel portion (16b) that can be filled with the chemical liquid (M) therein, a distal end cylindrical portion (16d) that protrudes in the distal direction from the barrel portion (16b) and has a distal end opening (16f) at the distal end; A barrel (16) having a sealing member, a sealing member (24) made of an elastic material for liquid-tightly sealing the tip opening (16f), and the sealing member (24) on the tip tube portion (16d). The said chemical | medical solution container provided with the fixing member (26) to fix, the housing main body (20) holding the said chemical | medical solution container, and it protrudes from the said housing main body (20), and surrounds the outer peripheral surface of the said front-end | tip cylinder part (16d). Preparing the housing (18) having the guide tube portion (22) disposed substantially concentrically with the tip tube portion (16d),
    A needle tube (36) having a needle tip (36b) through which the sealing member (24) can be pierced; and a connector body (34) for holding the needle tube (36), wherein the connector body (34) A base portion (38a) for holding the needle tube (36) so that the needle tip (36b) is a free end, and a protrusion projecting from the base portion (38a) so as to surround an outer peripheral surface of the needle tube (36). A guide tube portion (40a) arranged substantially concentrically with the needle tube (36), and protrudes along the needle tube (36) from the base portion (38a), and the needle tube (36) and the guide tube portion ( 40a), and the connector (30) having an engaging portion (54) engageable with the tip tube portion (16d),
    By moving the connector (30) toward the housing (18) with the needle tip (36b) of the connector (30) facing the sealing member (24) of the chemical solution container, Inserting the guide tube portion (22) of the housing (18) into the guide receiving tube portion (40a) of the connector body (34);
    After the insertion of the guide tube portion (22) into the guide receiving tube portion (40a), the needle tip (36b) starts to pierce the sealing member (24) and the engagement of the connector main body (34). Insert the joint portion (54) between the tip tube portion (16d) and the guide tube portion (22),
    After engaging the sealing member (24) with the needle tube (36), the engagement portion (54) and the tip tube portion (16d) are engaged.
    A connection method characterized by that.
PCT/JP2018/010170 2017-03-16 2018-03-15 Liquid medicine administration system WO2018168989A1 (en)

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JPWO2020195363A1 (en) * 2019-03-26 2020-10-01

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WO2019182031A1 (en) * 2018-03-20 2019-09-26 テルモ株式会社 Cap and syringe assembly and manufacturing method therefor
JPWO2019182031A1 (en) * 2018-03-20 2021-03-11 テルモ株式会社 Cap, syringe assembly and its manufacturing method
JP7201663B2 (en) 2018-03-20 2023-01-10 テルモ株式会社 Cap, syringe assembly and manufacturing method thereof
US11938305B2 (en) 2018-03-20 2024-03-26 Terumo Kabushiki Kaisha Cap, syringe assembly and manufacturing method thereof
JPWO2020195363A1 (en) * 2019-03-26 2020-10-01
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