WO2018155925A3 - 하이드로겔 중합체를 이용한 탈세포화 조직의 제조방법 및 이로부터 제조된 탈세포화 조직 - Google Patents

하이드로겔 중합체를 이용한 탈세포화 조직의 제조방법 및 이로부터 제조된 탈세포화 조직 Download PDF

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Publication number
WO2018155925A3
WO2018155925A3 PCT/KR2018/002182 KR2018002182W WO2018155925A3 WO 2018155925 A3 WO2018155925 A3 WO 2018155925A3 KR 2018002182 W KR2018002182 W KR 2018002182W WO 2018155925 A3 WO2018155925 A3 WO 2018155925A3
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WO
WIPO (PCT)
Prior art keywords
decellularized tissue
tissue
producing
produced
hydrogel polymer
Prior art date
Application number
PCT/KR2018/002182
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English (en)
French (fr)
Other versions
WO2018155925A2 (ko
Inventor
선웅
Original Assignee
고려대학교 산학협력단
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Priority claimed from KR1020180019893A external-priority patent/KR20180099482A/ko
Application filed by 고려대학교 산학협력단 filed Critical 고려대학교 산학협력단
Publication of WO2018155925A2 publication Critical patent/WO2018155925A2/ko
Publication of WO2018155925A3 publication Critical patent/WO2018155925A3/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Transplantation (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)

Abstract

본 발명은 탈세포화 조직의 제조방법 및 이로부터 제조된 탈세포화 조직에 관한 것으로, 본 발명의 탈세포화 조직의 제조방법은 탈세포화 과정에서 세포외기질 단백질의 손실을 방지하고 조직의 구조 특성을 유지하며, 조직의 종류에 관계없이 효율적으로 조직 내 세포를 제거할 수 있고, 이로부터 제조된 탈세포화 조직은 세포 배양용 지지체, 조직 이식용 소재, 수복재 또는 인공 장기용 소재로 이용될 수 있다.
PCT/KR2018/002182 2017-02-27 2018-02-22 하이드로겔 중합체를 이용한 탈세포화 조직의 제조방법 및 이로부터 제조된 탈세포화 조직 WO2018155925A2 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR10-2017-0025622 2017-02-27
KR20170025622 2017-02-27
KR10-2018-0019893 2018-02-20
KR1020180019893A KR20180099482A (ko) 2017-02-27 2018-02-20 하이드로겔 중합체를 이용한 탈세포화 조직의 제조방법 및 이로부터 제조된 탈세포화 조직

Publications (2)

Publication Number Publication Date
WO2018155925A2 WO2018155925A2 (ko) 2018-08-30
WO2018155925A3 true WO2018155925A3 (ko) 2019-03-14

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Application Number Title Priority Date Filing Date
PCT/KR2018/002182 WO2018155925A2 (ko) 2017-02-27 2018-02-22 하이드로겔 중합체를 이용한 탈세포화 조직의 제조방법 및 이로부터 제조된 탈세포화 조직

Country Status (1)

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WO (1) WO2018155925A2 (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230077632A1 (en) * 2020-02-17 2023-03-16 Venus Medtech (Hangzhou) Inc. Functionalized biological matrix material, preparation method therefor and use thereof
CN111184914B (zh) * 2020-02-17 2021-10-15 四川大学 一种功能化脱细胞基质生物材料及其制备方法和应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120264190A1 (en) * 2009-12-21 2012-10-18 The Regents Of The University Of California Decellularized and Delipidized Extracellular Matrix and Methods of Use
KR20150043241A (ko) * 2012-08-09 2015-04-22 더 보드 오브 트러스티스 오브 더 리랜드 스탠포드 쥬니어 유니버시티 현미경적 분석을 위한 생물학적 표본을 준비하기 위한 방법과 조성물
US20160305856A1 (en) * 2015-04-14 2016-10-20 Massachusetts Institute Of Technology Iterative expansion microscopy
WO2017031249A1 (en) * 2015-08-17 2017-02-23 California Institute Of Technology Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high resolution intact circuit mapping and phenotyping

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120264190A1 (en) * 2009-12-21 2012-10-18 The Regents Of The University Of California Decellularized and Delipidized Extracellular Matrix and Methods of Use
KR20150043241A (ko) * 2012-08-09 2015-04-22 더 보드 오브 트러스티스 오브 더 리랜드 스탠포드 쥬니어 유니버시티 현미경적 분석을 위한 생물학적 표본을 준비하기 위한 방법과 조성물
US20160305856A1 (en) * 2015-04-14 2016-10-20 Massachusetts Institute Of Technology Iterative expansion microscopy
WO2017031249A1 (en) * 2015-08-17 2017-02-23 California Institute Of Technology Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high resolution intact circuit mapping and phenotyping

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SALDIN, L. T. ET AL.: "Extracellular Matrix Hydrogels from Decellularized Tissues: Structure and Function", ACTA BIOMATERIALIA, vol. 49, 1 December 2016 (2016-12-01), pages 1 - 15, XP029885847, DOI: doi:10.1016/j.actbio.2016.11.068 *

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