WO2018137335A1 - 一种血液检测方法及设备 - Google Patents

一种血液检测方法及设备 Download PDF

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WO2018137335A1
WO2018137335A1 PCT/CN2017/097791 CN2017097791W WO2018137335A1 WO 2018137335 A1 WO2018137335 A1 WO 2018137335A1 CN 2017097791 W CN2017097791 W CN 2017097791W WO 2018137335 A1 WO2018137335 A1 WO 2018137335A1
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blood
blood sample
sample
sampling needle
routine
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PCT/CN2017/097791
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French (fr)
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白新梅
张勇
邵汉荣
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深圳开立生物医疗科技股份有限公司
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Publication of WO2018137335A1 publication Critical patent/WO2018137335A1/zh

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N2001/002—Devices for supplying or distributing samples to an analysing apparatus

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  • the invention relates to the field of blood analysis, in particular to a blood detecting method, and to a blood detecting device.
  • CRP C-reactive protein
  • the reagents used are different, so at least two separate channels are required for measurement, and independent sample collection and distribution are required for these channels.
  • the existing method is to take an appropriate amount of blood at a time, and then realize sample distribution to different detection channels by quantitative control. That is, firstly, a certain amount of blood satisfying the measurement requirement is sucked through the sampling needle, and blood is sequentially distributed to each measurement module, but the blood of the isolation section needs to be set before the blood is distributed to each measurement module, and the blood of the isolation section is discarded.
  • the CRP channel and the blood channel are independently assigned blood samples, the total blood volume is increased, or the corresponding blood routine module sample is reduced, thereby weakening the competitiveness of the product in blood sample consumption, or affecting blood routine.
  • the module detects the accuracy level of the project; at the same time, the isolated segment samples are set in each allocation segment, which invisibly increases the overall sample consumption and wastes.
  • the present invention provides a blood detecting method, comprising:
  • controlling the sampling needle to dispense the initial blood sample to the blood routine measurement module further comprises diluting the initial blood sample, the second blood sample being specifically the partially diluted blood sample.
  • controlling the sampling needle after collecting the initial blood sample further comprises discarding the first segment of the initial blood sample of the preset dose.
  • controlling the sampling needle to allocate the initial blood sample to a blood routine measurement module in particular, controlling the sampling needle to sequentially distribute the initial blood sample to a plurality of blood routine measurement modules;
  • the controlling the sampling needle collects a second blood sample from the blood routine measuring module, specifically, controlling the sampling needle to collect the second blood sample into the first type of blood routine measuring module.
  • controlling the sampling needle to distribute the second blood sample to the CRP measurement module further comprises controlling the sampling needle to sequentially distribute the second blood sample to a plurality of second type blood routine measurement modules;
  • the second blood sample in the second type of blood routine measurement module is subjected to blood routine examination.
  • controlling the sampling needle to sequentially distribute the second blood sample to the plurality of second type blood routine measurement modules further comprises cleaning the sampling needle.
  • the total dose of the initial blood sample is the predetermined dose of the first segment of the initial blood sample discarded and the divided dose of the initial blood sample allocated in each of the blood routine measurement modules with;
  • the total dose of the secondary blood sample is a divided dose of the secondary blood sample distributed in the CRP measuring module and a divided dose of the secondary blood sample distributed in each of the two types of blood routine measuring modules with.
  • the invention also provides a blood testing device comprising:
  • Blood routine measurement module for blood routine testing
  • a controller configured to control the sampling needle to collect the initial blood sample, and then allocate the initial blood sample to the blood routine measurement module, and control to control the sampling needle to be collected by the blood routine measurement module after collecting the second blood sample
  • the secondary blood sample is dispensed to the CRP measurement module.
  • the blood routine measurement module includes a plurality of blood routine measurement modules for detecting the initial blood samples and a plurality of blood routine measurement modules for detecting the secondary blood samples.
  • the invention provides a blood detecting method, comprising: controlling a sampling needle to collect an initial blood sample; controlling a sampling needle to allocate an initial blood sample to a blood routine measuring module; controlling the sampling needle to collect a second blood sample from a blood routine measuring module; and controlling the sampling needle
  • a secondary blood sample is dispensed to the CRP measurement module; a blood routine test is performed on the initial blood sample in the blood routine measurement module, and a CRP test is performed on the secondary blood sample in the CRP measurement module.
  • the secondary blood sample required for CRP detection is collected from the blood routine measurement module.
  • Increasing the test item does not increase the blood volume.
  • the total blood volume is always the dose of the initial blood sample collected. Do not set up isolated segment samples to reduce the total consumption of blood samples and avoid waste.
  • the present invention also provides a blood detecting device using the above blood detecting method. Since the blood detecting method has the above technical effects, the blood detecting device should have the same technical effect, and will not be described in detail herein.
  • FIG. 1 is a flow chart of a specific embodiment of a blood detecting method provided by the present invention.
  • FIG. 2 is a specific embodiment of a blood detecting method provided by the present invention in a dispensing process Schematic diagram of the state changes of blood samples inside the sampling needle at different stages.
  • the core of the present invention is to provide a blood detecting method capable of reducing the total consumption of blood samples and improving the detection accuracy.
  • Another core of the present invention is to provide a blood detecting device capable of reducing the total consumption of blood samples and improving the detection accuracy. Sex.
  • FIG. 1 is a flow chart of a specific embodiment of a blood detecting method according to the present invention.
  • the sampling needle is used to collect the initial blood sample. After the collection is completed, the first initial blood sample of the preset dose needs to be discarded to prevent contamination and improve the detection accuracy.
  • the sampling needle is controlled to dispense an initial blood sample to the blood routine measurement module.
  • the control sampling needle collects a secondary blood sample from the blood routine measurement module, that is, a part of the initial blood sample distributed to the blood routine measurement module before the collection as a secondary blood sample.
  • the sampling needle is controlled to dispense a secondary blood sample to the CRP measurement module.
  • the secondary blood sample required for CRP detection is collected by the blood routine measurement module. Increasing the test item does not increase the blood volume. The total blood volume is always the dose of the initial blood sample collected. Do not set up isolated segment samples to reduce the total consumption of blood samples and avoid waste.
  • the initial blood sample is further diluted to include the diluted initial blood sample, that is, the second blood sample is the partially diluted initial blood sample.
  • the initial blood sample is distributed to the blood routine measurement module for pre-dilution or hemolysis staining; then the secondary blood sample added to the CRP measurement module is Sampled from a pre-diluted reaction sample. That is to say, the sample added to the CRP measurement module in the present scheme is a pre-diluted sample obtained from the blood routine measurement module, which ensures the sample dose required during the detection process and improves the detection accuracy.
  • the blood routine measurement module may include a plurality of blood routine measurement modules to perform different detection items, so the control sampling needle is assigned to the blood routine measurement module to allocate an initial blood sample, specifically, the control sampling needle is sequentially distributed to a plurality of blood routine measurement modules. After the initial blood sample is allocated to the first type of blood routine measurement module, the sampling needle is moved to the next type of blood routine measurement module for sequential distribution until the initial blood sample distribution in the sampling needle is completed; The second blood sample is collected in the blood routine measurement module, and the second blood sample is collected from the first blood routine measurement module for controlling the sampling needle.
  • the control sample needle is assigned to the CRP measurement module to the second blood sample, the control sample needle is sequentially controlled to a plurality of types.
  • the blood routine measurement module allocates a secondary blood sample; and performs a blood routine examination on the secondary blood sample in the second type blood routine measurement module. After the sample is dispensed, the sample needle needs to be cleaned.
  • the total dose of the initial blood sample is the predetermined dose of the discarded first blood sample and the initial blood sample allocated in each type of blood routine measurement module.
  • the sum of the doses, that is, the discarded first sample, the remaining initial blood samples are all distributed to the measurement module, and no isolation segment is provided to avoid waste.
  • the total dose of the secondary blood sample is the sum of the divided dose of the secondary blood sample distributed in the CRP measuring module and the divided dose of the secondary blood sample distributed in each of the two types of blood conventional measuring modules, that is, the second collected Blood samples are also all dispensed into the corresponding measurement module, with no discarded samples.
  • a specific embodiment of the present invention also provides a blood detecting apparatus using the above blood detecting method, comprising a sampling needle for collecting a blood sample, a blood conventional measuring module for performing blood routine detection, and a CRP measuring module for performing CRP detection. And a controller, wherein the controller is configured to control the sampling needle to collect the initial blood sample, and then allocate the initial blood sample to the blood routine measuring module, and control the sampling needle to be collected from the blood routine measuring module to the CRP measuring module.
  • the blood routine measurement module includes a plurality of blood routine measurement modules for detecting initial blood samples and a plurality of blood routine measurement modules for detecting secondary blood samples. Piece.
  • FIG. 2 is a schematic diagram showing the state change of the blood sample inside the sampling needle at different stages in the dispensing process according to a specific embodiment of the blood detecting method provided by the present invention.
  • 1 is the first sample to be discarded
  • 2 is the sample allocated in the first blood routine measurement module
  • 3 is the sample assigned in the subsequent blood routine measurement module
  • 4 is the sample allocated in the CRP measurement module.
  • a sample assigned to a blood test module of the second type. 4 and 5 are pre-diluted samples obtained from the first class of blood routine measurement modules. Specific steps are as follows:
  • the sampling needle collects a certain amount of blood from the tube in which the blood sample is stored, as shown by A, the first sample of the preset dose is discarded, and the sample state inside the sampling needle is as shown in B.
  • the sampling needle distributes the sample to the first type of blood routine measurement module. After completion, the sample state in the sampling needle is as shown in C.
  • the sampling needle distributes the sample to the subsequent blood routine measurement module.
  • the sample state in the sampling needle is as shown in D. At this time, the collected blood sample in the sampling needle has been allocated.
  • the sampling needle collects a certain amount of diluted blood sample into the first blood type conventional measurement module. After completion, the sample state in the sampling needle is as shown in E.
  • the sampling needle distributes the sample to the CRP measuring module. After completion, the sample state in the sampling needle is as shown in F.
  • the sampling needle distributes the sample to the second type blood routine measurement module. After completion, the sample state in the sampling needle is as shown in G; at this time, the pre-dilution blood sample collected from the first type of blood routine measurement module in the sampling needle has been dispensed, and the cleaning is performed. Sampling needle.

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Abstract

一种血液检测方法及应用血液检测方法的血液检测设备，血液检测方法包括控制采样针采集初始血液样本；控制采样针向血常规测量模块分配初始血液样本；控制采样针由血常规测量模块内采集二次血液样本；控制采样针向CRP测量模块分配二次血液样本；对血常规测量模块内的初始血液样本进行血常规检测，对CRP测量模块内的二次血液样本进行CRP检测。在检测过程中，进行CRP检测需要的二次血液样本是由血常规测量模块内的初始血液样本采集的，增加检测项目也不会增加用血量，总用血量一直是采集的初始血液样本的剂量，同时不设置隔离段样本，减少血液样本总消耗量，避免浪费。

Description

一种血液检测方法及设备
本申请要求于2017年1月24日提交中国专利局、申请号为201710060153.9、发明名称为“一种血液检测方法及设备”的中国专利申请的优先权，其全部内容通过引用结合在本申请中。
技术领域
本发明涉及血液分析领域，特别是涉及一种血液检测方法，还涉及一种血液检测设备。
背景技术
在血液分析领域，血常规检测和C反应蛋白(CRP)的检测是目前应用最为普遍的部分。为了实现快速对血常规以及CRP参数的检测从而满足临床检测需求，需要将血液分析仪中集成血常规检测模块和CRP检测模块。
由于血常规和CRP的检测原理，使用试剂均不相同，因此至少需要独立的两个通道测量，并且需对这些通道进行独立的样本采集与分配。现有的方法为一次性吸取适量的血液，然后通过定量控制分别实现对不同检测通道的样本分配。即首先通过采样针吸取一定量满足测量要求的血液，依次向每个测量模块分配血液，但是向每个测量模块分配血液前需要设置隔离段血液，并将隔离段血液弃掉。
这种方式由于CRP通道和血常规通道独立分配血样，增加了总体的用血量，或是相应的血常规模块样本量减少，因此弱化了产品在血液样本消耗方面的竞争力，或影响血常规模块检测项目的准确性水平；同时在每个分配段都设置隔离段样本，无形又增加了总体的样本消耗，造成浪费。
因此，如何提供一种减少血液样本总消耗量并提高检测准确性的血液检测方法是本领域技术人员目前需要解决的技术问题。
发明内容
本发明的目的是提供一种血液检测方法，能够减少血液样本总消耗量 并提高检测准确性，本发明的另一目的是提供一种血液检测设备，能够减少血液样本总消耗量并提高检测准确性。
为解决上述技术问题，本发明提供一种血液检测方法，包括：
控制采样针采集初始血液样本；
控制所述采样针向血常规测量模块分配所述初始血液样本；
控制所述采样针由所述血常规测量模块内采集二次血液样本；
控制所述采样针向CRP测量模块分配所述二次血液样本；
对所述血常规测量模块内的所述初始血液样本进行血常规检测，对所述CRP测量模块内的所述二次血液样本进行CRP检测。
优选地，控制所述采样针向血常规测量模块分配所述初始血液样本后还包括稀释所述初始血液样本，所述二次血液样本具体为部分稀释后的所述初始血液样本。
优选地，所述控制采样针采集初始血液样本后还包括弃掉预设剂量的首段所述初始血液样本。
优选地，所述控制所述采样针向血常规测量模块分配所述初始血液样本具体为控制所述采样针依次向多个一类血常规测量模块分配所述初始血液样本；
所述控制所述采样针由所述血常规测量模块内采集二次血液样本具体为控制所述采样针向首个所述一类血常规测量模块内采集所述二次血液样本。
优选地，所述控制所述采样针向CRP测量模块分配所述二次血液样本后还包括控制所述采样针依次向多个二类血常规测量模块分配所述二次血液样本；对所述二类血常规测量模块内的所述二次血液样本进行血常规检查。
优选地，所述控制所述采样针依次向多个二类血常规测量模块分配所述二次血液样本后还包括清洗所述采样针。
优选地，所述初始血液样本的总剂量为弃掉的首段所述初始血液样本的所述预设剂量与各所述一类血常规测量模块内分配的所述初始血液样本的分剂量之和；
所述二次血液样本的总剂量为所述CRP测量模块内分配的所述二次血液样本的分剂量与各所述二类血常规测量模块内分配的所述二次血液样本的分剂量之和。
本发明还提供一种血液检测设备，包括：
采样针，用于采集血液样本；
血常规测量模块，用于进行血常规检测；
CRP测量模块，用于进行CRP检测；
控制器，用于控制所述采样针采集初始血液样本后向所述血常规测量模块分配所述初始血液样本，并控制控制所述采样针由所述血常规测量模块内采集二次血液样本后向所述CRP测量模块分配所述二次血液样本。
优选地，所述血常规测量模块包括多个用于检测所述初始血液样本的一类血常规测量模块和多个用于检测所述二次血液样本的二类血常规测量模块。
本发明提供了一种血液检测方法，包括控制采样针采集初始血液样本；控制采样针向血常规测量模块分配初始血液样本；控制采样针由血常规测量模块内采集二次血液样本；控制采样针向CRP测量模块分配二次血液样本；对血常规测量模块内的初始血液样本进行血常规检测，对CRP测量模块内的二次血液样本进行CRP检测。在检测过程中，进行CRP检测需要的二次血液样本是从血常规测量模块内采集的，增加检测项目也不会增加用血量，总用血量一直是采集的初始血液样本的剂量，同时不设置隔离段样本，减少血液样本总消耗量，避免浪费。
本发明还提供一种应用上述血液检测方法的血液检测设备，由于上述血液检测方法具有上述技术效果，上述血液检测设备也应具有同样的技术效果，在此不再详细介绍。
附图说明
图1为本发明所提供的血液检测方法的一种具体实施方式的流程框图；
图2为本发明所提供的血液检测方法的一种具体实施方式在分配过程 中不同阶段下采样针内部血液样本状态变化示意图。
具体实施方式
本发明的核心是提供一种血液检测方法，能够减少血液样本总消耗量并提高检测准确性，本发明的另一核心是提供一种血液检测设备，能够减少血液样本总消耗量并提高检测准确性。
为了使本技术领域的人员更好地理解本发明方案，下面结合附图和具体实施方式对本发明作进一步的详细说明。
请参考图1，图1为本发明所提供的血液检测方法的一种具体实施方式的流程框图。
本发明具体实施方式提供的血液检测方法，包括步骤：
控制采样针采集初始血液样本，采集完成后还需要弃掉预设剂量的首段初始血液样本，防止污染，提高检测准确性。
控制采样针向血常规测量模块分配初始血液样本。
控制采样针由血常规测量模块内采集二次血液样本，即采集之前向血常规测量模块内分配的部分初始血液样本作为二次血液样本。
控制采样针向CRP测量模块分配二次血液样本。
对血常规测量模块内的初始血液样本进行血常规检测，对CRP测量模块内的二次血液样本进行CRP检测，完成相应的检测项目，可以在样本分配完成后同时进行两种检测，也可每个模块内分配完成后直接单独进行检测，均在本发明的保护范围之内。
在检测过程中，进行CRP检测需要的二次血液样本是由血常规测量模块内采集的，增加检测项目也不会增加用血量，总用血量一直是采集的初始血液样本的剂量，同时不设置隔离段样本，减少血液样本总消耗量，避免浪费。
在本发明具体实施方式提供的血液检测方法中，控制采样针向血常规测量模块分配初始血液样本后还包括稀释初始血液样本，即二次血液样本为部分稀释后的初始血液样本。将初始血液样本分配至血常规测量模块进行预稀释或是溶血染色等反应；之后加入CRP测量模块的二次血液样本是 从预稀释反应过的血样中采样获得的。也就是说，本方案中加入到CRP测量模块中的样本是从血常规测量模块中取得的预稀释过的样本，保证检测过程中需要的样本剂量，提高检测准确性。
血常规测量模块可以包括多个一类血常规测量模块，进行不同的检测项目，因此控制采样针向血常规测量模块分配初始血液样本具体为控制采样针依次向多个一类血常规测量模块分配初始血液样本，即向首个一类血常规测量模块分配样本后，采样针移至下个一类血常规测量模块进行依次分配，直至将采样针内的初始血液样本分配完成；控制采样针由血常规测量模块内采集二次血液样本具体为控制采样针由首个一类血常规测量模块内采集二次血液样本。
还可增加新的血常规检测项目，使用二次血液样本，仍不会增加血液总消耗量，因此控制采样针向CRP测量模块分配二次血液样本后还包括控制采样针依次向多个二类血常规测量模块分配二次血液样本；对二类血常规测量模块内的二次血液样本进行血常规检查。完成样本分配后，还需要清洗采样针。
在上述各具体实施方式提供的血液检测方法的基础上，初始血液样本的总剂量为弃掉的首段初始血液样本的预设剂量与各一类血常规测量模块内分配的初始血液样本的分剂量之和，即除去弃掉的首段样本，其余的初始血液样本全部分配至测量模块中，也不设置隔离段，避免浪费。同样地，二次血液样本的总剂量为CRP测量模块内分配的二次血液样本的分剂量与各二类血常规测量模块内分配的二次血液样本的分剂量之和，即采集的二次血液样本也全部分配至对应的测量模块中，没有弃掉的样本。
本发明具体实施方式还提供一种应用上述血液检测方法的血液检测设备，包括用于采集血液样本的采样针、用于进行血常规检测的血常规测量模块、用于进行CRP检测的CRP测量模块和控制器，其中，控制器用于控制采样针采集初始血液样本后向血常规测量模块分配初始血液样本，并控制控制采样针由血常规测量模块内采集二次血液样本后向CRP测量模块分配二次血液样本。血常规测量模块包括多个用于检测初始血液样本的一类血常规测量模块和多个用于检测二次血液样本的二类血常规测量模 块。
具体地，可以设置两个一类血常规测量模块、一个CRP测量模块和一个二类血常规测量模块，也可根据情况调整各模块的数量，均在本发明的保护范围之内。请参考图2，图2为本发明所提供的血液检测方法的一种具体实施方式在分配过程中不同阶段下采样针内部血液样本状态变化示意图。
其中1为要抛弃掉的首段样本，2为首个一类血常规测量模块中分配的样本，3为后续一类血常规测量模块中分配的样本，4为CRP测量模块中分配的样本，5为二类血常规测量模块中分配的样本。4和5是从首个一类血常规测量模块中获得的预稀释过的样本。具体步骤如下：
在采样针从储存有血样的试管中采集了一定量血液后如A所示，会将预设剂量的首段样本抛弃掉，此时采样针内部的样本状态如B所示。
采样针向首个一类血常规测量模块分配样本，完毕后，采样针内的样本状态如C所示。
采样针向后续一类血常规测量模块分配样本，采样针内的样本状态如D所示，此时采样针内的采集血样已分配完毕。
采样针向首个一类血常规测量模块中采集一定量稀释过的血样，完毕后，采样针内的样本状态如E所示。
采样针向CRP测量模块分配样本，完毕后，采样针内的样本状态如F所示。
采样针向二类血常规测量模块分配样本，完毕后，采样针内的样本状态如G所示；此时采样针内从首个一类血常规测量模块采集的预稀释血样已分配完毕，清洗采样针。
以上对本发明所提供的血液检测方法进行了详细介绍。本文中应用了具体个例对本发明的原理及实施方式进行了阐述，以上实施例的说明只是用于帮助理解本发明的方法及其核心思想。应当指出，对于本技术领域的普通技术人员来说，在不脱离本发明原理的前提下，还可以对本发明进行若干改进和修饰，这些改进和修饰也落入本发明权利要求的保护范围内。

Claims (9)

  1. 一种血液检测方法，其特征在于，包括：
    控制采样针采集初始血液样本；
    控制所述采样针向血常规测量模块分配所述初始血液样本；
    控制所述采样针由所述血常规测量模块内采集二次血液样本；
    控制所述采样针向CRP测量模块分配所述二次血液样本；
    对所述血常规测量模块内的所述初始血液样本进行血常规检测，对所述CRP测量模块内的所述二次血液样本进行CRP检测。
  2. 根据权利要求1所述的血液检测方法，其特征在于，控制所述采样针向血常规测量模块分配所述初始血液样本后还包括稀释所述初始血液样本，所述二次血液样本具体为部分稀释后的所述初始血液样本。
  3. 根据权利要求2所述的血液检测方法，其特征在于，所述控制采样针采集初始血液样本后还包括弃掉预设剂量的首段所述初始血液样本。
  4. 根据权利要求3所述的血液检测方法，其特征在于，所述控制所述采样针向血常规测量模块分配所述初始血液样本具体为控制所述采样针依次向多个一类血常规测量模块分配所述初始血液样本；
    所述控制所述采样针由所述血常规测量模块内采集二次血液样本具体为控制所述采样针向首个所述一类血常规测量模块内采集所述二次血液样本。
  5. 根据权利要求4所述的血液检测方法，其特征在于，所述控制所述采样针向CRP测量模块分配所述二次血液样本后还包括控制所述采样针依次向多个二类血常规测量模块分配所述二次血液样本；对所述二类血常规测量模块内的所述二次血液样本进行血常规检查。
  6. 根据权利要求5所述的血液检测方法，其特征在于，所述控制所述采样针依次向多个二类血常规测量模块分配所述二次血液样本后还包括清洗所述采样针。
  7. 根据权利要求1至6任意一项所述的血液检测方法，其特征在于，所述初始血液样本的总剂量为弃掉的首段所述初始血液样本的所述预设剂量与各所述一类血常规测量模块内分配的所述初始血液样本的分剂量之 和；
    所述二次血液样本的总剂量为所述CRP测量模块内分配的所述二次血液样本的分剂量与各所述二类血常规测量模块内分配的所述二次血液样本的分剂量之和。
  8. 一种血液检测设备，其特征在于，包括：
    采样针，用于采集血液样本；
    血常规测量模块，用于进行血常规检测；
    CRP测量模块，用于进行CRP检测；
    控制器，用于控制所述采样针采集初始血液样本后向所述血常规测量模块分配所述初始血液样本，并控制控制所述采样针由所述血常规测量模块内采集二次血液样本后向所述CRP测量模块分配所述二次血液样本。
  9. 根据权利要求8所述的血液检测设备，其特征在于，所述血常规测量模块包括多个用于检测所述初始血液样本的一类血常规测量模块和多个用于检测所述二次血液样本的二类血常规测量模块。
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CN106771107A (zh) * 2017-01-24 2017-05-31 深圳开立生物医疗科技股份有限公司 一种血液检测方法及设备
CN109342749A (zh) * 2018-11-16 2019-02-15 陈大为 一种整合血碘检测的血常规试剂盒及全自动血球仪
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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6106778A (en) * 1997-09-27 2000-08-22 Horiba, Ltd. Blood cell count/immunoassay apparatus using whole blood
CN204595006U (zh) * 2015-05-12 2015-08-26 江苏英诺华医疗技术有限公司 一种同时具有血液常规和生化检测功能的分析仪
CN105334332A (zh) * 2014-07-01 2016-02-17 深圳迈瑞生物医疗电子股份有限公司 样本分析仪及其样本采集和分配方法
CN105699380A (zh) * 2016-03-23 2016-06-22 深圳市帝迈生物技术有限公司 一种可同时测量crp和血常规的分析设备和方法
CN106771107A (zh) * 2017-01-24 2017-05-31 深圳开立生物医疗科技股份有限公司 一种血液检测方法及设备

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6106778A (en) * 1997-09-27 2000-08-22 Horiba, Ltd. Blood cell count/immunoassay apparatus using whole blood
CN105334332A (zh) * 2014-07-01 2016-02-17 深圳迈瑞生物医疗电子股份有限公司 样本分析仪及其样本采集和分配方法
CN204595006U (zh) * 2015-05-12 2015-08-26 江苏英诺华医疗技术有限公司 一种同时具有血液常规和生化检测功能的分析仪
CN105699380A (zh) * 2016-03-23 2016-06-22 深圳市帝迈生物技术有限公司 一种可同时测量crp和血常规的分析设备和方法
CN106771107A (zh) * 2017-01-24 2017-05-31 深圳开立生物医疗科技股份有限公司 一种血液检测方法及设备

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