WO2018026892A1 - Appareil intra-oral pour applications multiples de traitement - Google Patents

Appareil intra-oral pour applications multiples de traitement Download PDF

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Publication number
WO2018026892A1
WO2018026892A1 PCT/US2017/045053 US2017045053W WO2018026892A1 WO 2018026892 A1 WO2018026892 A1 WO 2018026892A1 US 2017045053 W US2017045053 W US 2017045053W WO 2018026892 A1 WO2018026892 A1 WO 2018026892A1
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WO
WIPO (PCT)
Prior art keywords
energization
intraoral device
mouth
intraoral
leds
Prior art date
Application number
PCT/US2017/045053
Other languages
English (en)
Inventor
John Allen HENDY
John Joseph REISENHOFER
Original Assignee
Hendy John Allen
Reisenhofer John Joseph
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hendy John Allen, Reisenhofer John Joseph filed Critical Hendy John Allen
Publication of WO2018026892A1 publication Critical patent/WO2018026892A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C19/00—Dental auxiliary appliances
    • A61C19/06—Implements for therapeutic treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0601—Apparatus for use inside the body
    • A61N5/0603—Apparatus for use inside the body for treatment of body cavities
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/0624—Apparatus adapted for a specific treatment for eliminating microbes, germs, bacteria on or in the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/067—Radiation therapy using light using laser light
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0601—Apparatus for use inside the body
    • A61N5/0603—Apparatus for use inside the body for treatment of body cavities
    • A61N2005/0606—Mouth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0601—Apparatus for use inside the body
    • A61N2005/0612—Apparatus for use inside the body using probes penetrating tissue; interstitial probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/063—Radiation therapy using light comprising light transmitting means, e.g. optical fibres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/065—Light sources therefor
    • A61N2005/0651—Diodes
    • A61N2005/0652—Arrays of diodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0659—Radiation therapy using light characterised by the wavelength of light used infrared
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0662—Visible light
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0662—Visible light
    • A61N2005/0663—Coloured light

Definitions

  • This disclosure is directed generally to intraoral appliances, and more specifically to an appliance that may be controlled to deliver different wavelengths of radiation (such as, for example, LED radiation or laser radiation) according to a customized program configured by the dental professional.
  • the controlled exposure to such radiation is useful in treatment of oral conditions.
  • LEDs light emitting diodes
  • the irradiated wavelengths of the LEDs define specific actions of which the appliance is capable.
  • Some prior art LED appliances work in specific wavelengths, or limited ranges, restricting their potential uses and applications. Most are in the blue and lower red regions or the visible light spectrum.
  • Our present intraoral appliance evolved out of substantial proprietary and confidential research and development of application of LLLT for intraoral healing, infection control, guided tissue regeneration, osteogenic proliferation and osseous regeneration.
  • Our appliance provides a very accurate and controlled delivery of a wide range of LLLT treatment options.
  • Our appliance is very versatile, giving the dental professional a high level of control associated with the variables of LLLT.
  • the present appliance thus allows the dental professional to treat the patient with a highly controlled and targeted course of LLLT. This allows the dental professional to use our intraoral appliance to treat and remediate a wide range of conditions presented by various patients.
  • intraoral appliance mainly with reference to embodiments that enable light-emitting diode (LED) radiation
  • embodiments are also described herein which enable laser radiation for alternative LLLT regimens.
  • the scope of this disclosure is not limited to any particular radiation source (such as LEDs or lasers) for treatment.
  • the scope of this disclosure includes intraoral appliances deploying hybrid sources of radiation for treatment (e.g. LEDs and lasers).
  • the technical advantages provided by our intraoral appliance thus include, without limitation, improved healing after oral surgery and periodontal surgery, improved regeneration of hard and soft tissues in gum disease therapy, improved remediation of intraoral infection, and improved and rapid movement of teeth redirected via orthodontics stimulation.
  • Our disclosed intraoral appliance is advantageously configured to deliver the proper amount of energy to the correct locations to render rapid healing and/or remediate bacterial growth.
  • healing can be promoted and bacterial growth can be inhibited at the same time or during different treatment sessions by adjusting the disclosed powered time controls.
  • FIGURE 1 illustrates a first exemplary embodiment 100 of the disclosed intraoral appliance, deploying LEDs 102 for LLLT;
  • FIGURE 2 is a plan view of the embodiment depicted on FIGURE 1 ;
  • FIGURE 3 is a section as shown on FIGURE 2;
  • FIGURE 4 illustrates a second exemplary embodiment 200 of the disclosed intraoral appliance in which LLLT may be directed to a specific oral region
  • FIGURE 5 illustrates a third exemplary embodiment 300 of the disclosed intraoral appliance, similar to the embodiment of FIGURE 1 , except also providing rearward-radiating LEDs 302 for LLLT at the back of the mouth and throat;
  • FIGURE 6 illustrates a fourth exemplary embodiment of the disclosed intraoral appliance, similar to other illustrated embodiments, except using lasers as source of LLLT radiation;
  • FIGURE 7 is a section as shown on FIGURE 6; and FIGURE 8 illustrates an exemplary circuit diagram 800 for delivering power to the LEDs 102 on the intraoral appliance 100 depicted on FIGURE 1.
  • FIGURES 1 through 8 Exemplary embodiments of our disclosed intraoral appliance will now be described in detail with reference to the accompanying FIGURES 1 through 8. Where the same reference number or letter is used in FIGURES 1 through 8, the same part or feature of a disclosed embodiment is being identified on that Figure. In this way, reference numbers and letters on FIGURES 1 through 8 can be omitted for clarity on some views while still allowing the reader to understand the subject matter depicted on FIGURES 1 through 8.
  • FIGURE 1 illustrates a first exemplary embodiment 100 of the disclosed intraoral appliance, deploying LEDs 102 for LLLT.
  • FIGURE 2 is a plan view of intraoral appliance 100 on FIGURE 1
  • FIGURE 3 is a section as shown on FIGURE 2.
  • FIGURE 8 illustrates an exemplary circuit diagram 800 for delivering power to the LEDs 102 on FIGURE 1 in an "all on” or “all off power embodiment (i.e. LEDs 102 on FIGURE 1 not addressable with power individually or in groups thereof via circuit diagram 800).
  • the exemplary embodiment of intraoral appliance 100 provides 48 (forty-eight) LEDs 102 in total: 24 (twenty-four) LEDs 102 on each of the upper and lower arches lOl A and 101 B, each arch 101A, 101 B comprising 12 (twelve) LEDs 102 on each of the left and right sides, each side comprising 6 (six) LEDs 102 on each of the buccal and lingual faces.
  • LEDs 102 may be positioned to irradiate generally from the midline to about the second molars on both left and right sides of both the upper and lower jaws, from both lingual and buccal sides.
  • circuit diagram 800 depicts delivering power to the forty-eight LEDs 102 on FIGURES 1 and 2 in an "all on” or “all off' power embodiment.
  • Power supply 107 advantageously delivers 5 volts DC and is rated for 1 Amp delivered on a timer.
  • power supply 107 may be a GLO power supply, although this disclosure is not limited in this regard.
  • Power supply 107 may be any suitable power supply, operating off batteries or via connection to a mains power source.
  • multi-pin plug/receptacle connector is provided in line between power supply 107 and LEDs 102.
  • Power indicator LEDs 109 are further provided near the front of intraoral appliance 100, and act as an on/off indicator by illuminating with visible light when power is being delivered to LEDs 102.
  • LEDs 102 on FIGURE 8 are in groups of 3 (three) in series. LEDs 102 may each be rated for 1.5 volts, each consuming approximately 8 mW in power, and each drawing about 10 mA current. As shown on circuit diagram 800, parallel circuitry delivers 5 volts to each group of three LEDs 102. All forty-eight LEDs 102 together draw about 480 mA total. LEDs 102 preferably have a view angle (or emergence angle) in a range of at least about 60 degrees to about 80 degrees, and in some embodiments, in a range from about 120 degrees to about 180 degrees.
  • LEDs 102 may irradiate infra-red radiation in a range of about 810 nm to about 850 nm wavelength.
  • power supply 107 advantageously delivers power on a timer.
  • an 8-minute exposure of radiation of the foregoing configuration of LEDs 102 will deliver about 4.8 Joules/cm 2 to about 6 Joules/cm 2 of radiation within intraoral appliance 100.
  • LEDs 102 With placement of LEDs 102 at approximately one centimeter spacing and positioned at elevations "d" on FIGURE 3 to view/irradiate the cervical one third of the tooth, such an 8-minute exposure has been shown to deliver excellent healing results.
  • preferred embodiments further select "d" to be about 1 cm, although the scope of this disclosure is not limited to any particular value of'd”.
  • Power supply 107 on FIGURE 1 and circuit diagram 800 on FIGURE 8 are further not limited to the "all LEDs 102 on" or "all LEDs 102 off' embodiment illustrated and described above.
  • Other embodiments of power supply 107 and circuit diagram 800 may enable LEDs 102 to be individually addressed with power, or addressed with power in preselected groups thereof. Combining and/or sequencing hardware may then enable individual/grouped addressable LEDs 102 to follow preselected scripts of power supply and power cut, enabling corresponding patterns of radiation.
  • the dental professional may program LLLT regimens customized to the needs of the patient.
  • irradiated tissue cool-down periods maybe programmed into the script by de-energizing individual LEDs 102, or groups thereof, for predetermined periods. After cool-down, such LEDs 102 may be re-energized again to continue treatment. This may be important when working with infra-red radiation on sensitive oral tissue.
  • breathing holes 108 are provided to assist patient breathing while intraoral appliance 100 is in use.
  • multi-pin plug/receptacle 106 is provided in line between power supply 107 and LEDs 102.
  • Plug/receptacle 106 is located such that a pigtail 105 is provided extending from the front of intraoral appliance 100.
  • Pigtail 105 is advantageously long enough so that connection of intraoral appliance 100 to power supply 107 via plug/receptacle 106 may be made outside the patient's mouth.
  • this feature deters oral secretions from interfering with the electrical connections in plug/receptacle 106 during use of intraoral appliance 100. This feature further assists cleaning of intraoral appliance 100 after use, again by deterring cleaning fluids from interfering with plug/receptacle 106.
  • FIGURE 4 illustrates a second exemplary embodiment 200 of the disclosed intraoral appliance in which LLLT may be directed to a specific oral region.
  • intraoral appliance 200 on FIGURE 4 is similar in form, structure, components, features, circuitry and specification to the example of intraoral appliance 100 on FIGURE 1 , except that intraoral appliance 200 on FIGURE 4 provides 12 (twelve) LEDs 102, six on the buccal side of upper arch 201 A and six on the buccal side of lower arch 201 B. LEDs 102 on FIGURE 4 are focused on the front and outside of the jaws in order to provide localized LLLT in that specific oral region.
  • FIGURE 5 illustrates a third exemplary embodiment 300 of the disclosed intraoral appliance, similar to intraoral appliance 100 on FIGURE I , except also providing rearward- radiating LEDs 302 for LLLT at the back of the mouth and throat.
  • intraoral appliance 300 may treat, for example, conditions such as strep throat or temporomandibular joint (TMJ) disorders.
  • TMJ temporomandibular joint
  • intraoral appliance 300 on FIGURE 5 is similar in form, structure, components, features, circuitry and specification to the example of intraoral appliance 100 on FIGURE 1.
  • intraoral appliance 300 on FIGURE 5 also provides thickened portions 303 in the back regions of upper and lower arches 301 A, 30 IB.
  • FIGURE 5 Although illustrated on the lingual side, other embodiments may provide thickened portions 303 on the buccal side, or both sides. The scope of this disclosure is not limited in this regard.
  • FIGURE 5 further depicts thickened portions 303 providing rearward- radiating LEDs 302.
  • FIGURE 5 illustrates 2 (two) rearward-radiating LEDs 302 on each of 2 (two) thickened portions 303, the scope of this disclosure is again not limited in these regards.
  • LEDs 102, 302 are embedded in a conventional clear plastic or silicone material from which intraoral appliances 100, 200, 300 are formed, so that the irradiated energy is delivered without excessive heat buildup in the patient's tissues. Embedment in the conventional clear plastic or silicone material also protects the patient's mouth from electrical shock.
  • a pulsing of alternate LEDs 102, 302 and/or arches 101 A/B. 201 A/B, 301A/B may be provided and controlled by the power pack 107 and associated timer.
  • This pulsing option may be adjusted to very low energy levels for long durations, which has been demonstrated to help healing in cases of extreme oral tissue degeneration, such as, for example, with patients with AIDS or other auto immune diseases. Some research shows this type of low energy for long durations can boost natural immune defenses.
  • FIGURE 6 illustrates a fourth exemplary embodiment 400 of the disclosed intraoral appliance, similar to other exemplary embodiments illustrated on FIGURES 1 through 5 and described above, except that intraoral appliance 400 on FIGURE 6 deploys lasers as source of LLLT radiation.
  • FIGURE 7 is a section as shown on FIGURE 6. Looking at FIGURE 6, and with comparison to FIGURE 1 for example, intraoral appliance 400 on FIGURE 6 is similar in many regards to intraoral appliance 100 on FIGURE 1 , except that LEDs 102 on FIGURE 1 have been substituted for lasers 410 on FIGURE 6.
  • intraoral appliance 400 on FIGURE 6 provides 48 (forty-eight) lasers 410 in total : 24 (twenty-four) lasers 410 on each of the upper and lower arches 401 A and 401 B, each arch 401 A, 40 I B comprising 12 (twelve) lasers 410 on each of the left and right sides, each side comprising 6 (six) lasers 410 on each of the buccal and lingual faces.
  • lasers 410 on FIGURE 6 may be positioned to irradiate generally from the midline to about the second molars on both left and right sides of both the upper and lower jaws, from both lingual and buccal sides.
  • FIGURE 6 also illustrates breathing holes 408 to assist patient breathing while intraoral appliance 400 is in use.
  • Visual on/off indicator 409 is also provided.
  • Multi-line plug/receptacle 406 is further provided in line between laser power supply 407 and lasers 410.
  • Plug/receptacle 406 is located such that a pigtail 405 is provided extending from the front of intraoral appliance 400.
  • pigtail 405 on FIGURE 6 is advantageously long enough so that connection of intraoral appliance 400 to power supply 407 via plug/receptacle 406 may be made outside the patient's mouth.
  • FIGURE 7 depicts lasers 410 each being addressed by a separate laser supply line 41 1 (e.g. optical cable).
  • Each laser supply line 41 1 may be supplied by power supply 407 individually and/or in a predefined group thereof.
  • Lasers 410 may thus be individually addressable, or addressable in a predefined group thereof.
  • lasers 410 on FIGURES 6 and 7 may thus be programmed by the dental professional to follow an illumination script customized to the needs of the patient. The scope of this disclosure is not limited in this regard.
  • Different power supplies 407 may also energize different lasers 410 having different wavelengths. Conversely, multiple lasers 410 may be supplied by one power supply 407.
  • the scope of this disclosure is not limited in this regard. For example, in orthodontic applications, visible blue radiation (about 570 nm wavelength) will deter cavities from forming by killing bacteria, while infra-red radiation will minimize pain by reducing inflammation.
  • the disclosed intraoral appliance functions as a combined healing and rapid orthodontic stimulator, and advantageously applies the correct levels of radiation energy at the correct wavelengths in a manner that is controlled and definite to the target tissues.
  • Example 1 Using wavelengths in the infrared spectrum has been shown to help stimulate rapid redirection and movement of teeth in orthodontic applications. Our appliance has advanced orthodontic movement where desired results are now taking 1 -4 months, as compared to 2-3 years historically seen in conventional cases without infrared LLLT.
  • Example 2 These same infrared wavelengths can be used to stimulate proper and rapid healing after oral surgery, periodontal surgery, oral injuries, and oral stomatitis induced by cancer chemotherapy.
  • blue LEDs about 550 to about 570 nm wavelength
  • infrared LEDs about 800 nm to about 1064 nm wavelength
  • intraoral appliances described in this disclosure may be manufactured in a range of standard sizes to fit patients of various ages, having mouths of various dimensions. Additionally, intraoral appliances described herein may be made with extra-wide arches to accommodate patients with braces or other orthodontics.
  • the scope of our intraoral appliance is not limited to the exemplary embodiments illustrated on FIGURES 1 through 8, and alterations may be made to the exemplary embodiments of FIGURES 1 through 8 to offer different advantageous results.
  • such alterations may include: (1 ) positioning of the LEDs or lasers within the buccal or lingual flange (higher/lower or laterally), (2) the number of LEDs or lasers (including LED and laser hybrids), (3) the LED or laser irradiated wavelengths and combinations thereof, and (4) the script programmed into the power pack (or other ancillary control hardware) so that each combination of radiation sources can enable different patterns of time exposure and/or sequence exposure.
  • our appliance can be manufactured (A) with both upper and lower arches together or separate, or (B) upper and lower segmental arches restricting light exposure to only the upper and lower right side (appliance can then be flipped over to be use on the left side) or limited to the anterior 6 teeth also in either upper and lower or only one anterior sectional arch (which can be used either on upper or lower anterior 6 teeth).
  • the radiation sources on the appliance can also be positioned to expose any wavelength (visible or infrared, for example) at the posterior regions on either upper or lower arches, buccal or lingual sides, in order to irradiate the posterior oral cavity, lingual, and oropharynx.
  • any wavelength visible or infrared, for example
  • blue radiation sources positioned here, for example infections of the throat, soft palate and tonsils can be treated often without antibiotics.
  • infrared radiation sources added reduction of inflammation and association stimulation of healing of tissues can be accelerated by a factor of 4-6 times normal healing rates.
  • the lips can be treated with LLLT, which can be useful in stimulating healing with soft tissue procedures intraorally and extaorally for faster healing with fewer complications and less scarring.
  • a differently constructed appliance only using lingually positioned LEDs with irradiation directed toward the tongue and or palate, instead of toward the teeth and bone, can be used for promotion of rapid and uncomplicated healing after surgeries of the hard and soft palate or tongue.
  • Intraoral appliance with infrared and/or visible radiation sources exposed toward the posterior of the mouth and tongue, the throat and oropharynx.
  • each fiber optic strand in a bundle would have light emissions at each location described for the LEDs. Separate and different wavelengths of several lasers can be in one power pack and thereby produce the same range of visible and infrared emissions that the LEDs provide and at the same energy flow and positions.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dentistry (AREA)
  • Epidemiology (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

L'invention concerne également un dispositif intra-buccal, comprenant des arcs formés pour être reçus sur des ensembles de dents in situ dans une bouche. Des sources de rayonnement (de préférence des LEDs ou des lasers) sont prévues dans des ensembles, les ensembles étant déployés sur les arcs dans des emplacements prédéterminés de telle sorte que les sources de rayonnement dans de tels ensembles déployés sont disposées pour irradier des cibles présélectionnées à l'intérieur de la bouche. Une source de courant est configurée pour alimenter des ensembles de sources de rayonnement sélectionnés selon un script d'excitation/désexcitation prédéterminé, de préférence pendant des périodes sélectionnées selon une combinaison prédéterminée et une séquence d'excitation et de désexcitation de l'ensemble. Dans certains modes de réalisation, des sources de rayonnement irradient une lumière bleue (d'environ 650 nm à environ 670 nm de longueur d'onde) afin de remédier et de prévenir une infection, et/ou de la lumière infrarouge (d'environ 810 nm à environ 850 nm de longueur d'onde) afin de remédier à l'inflammation et de réduire la douleur.
PCT/US2017/045053 2016-08-02 2017-08-02 Appareil intra-oral pour applications multiples de traitement WO2018026892A1 (fr)

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US201662369843P 2016-08-02 2016-08-02
US62/369,843 2016-08-02

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Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019234308A1 (fr) * 2018-06-08 2019-12-12 Aalto University Foundation Sr Embout buccal et procédé de traitement intra-buccal
USD877340S1 (en) 2018-08-13 2020-03-03 Oral Care Products, Llc Dental mouthpiece for tooth whitening
CN112105418A (zh) * 2018-05-24 2020-12-18 亥伯龙医疗有限公司 用于生物光子组织治疗的设备
CN112641529A (zh) * 2019-10-11 2021-04-13 科伊特健康有限公司 用于口腔内治疗的口腔用具和方法
WO2021188279A1 (fr) * 2020-03-19 2021-09-23 Know Bio, Llc Dispositifs d'éclairage pour induire des effets biologiques
US11147984B2 (en) 2020-03-19 2021-10-19 Know Bio, Llc Illumination devices for inducing biological effects
US20220265409A1 (en) * 2021-02-22 2022-08-25 Dustin Lee Cohen Dental devices for simultaneous intra-oral and extra-oral treatments
US11524173B2 (en) 2015-07-28 2022-12-13 Know Bio, Llc Systems and methods for phototherapeutic modulation of nitric oxide
JP2022552665A (ja) * 2019-10-17 2022-12-19 ウェルスメディテック カンパニー，リミテッド マウスピース型治療器
WO2023039499A1 (fr) * 2021-09-09 2023-03-16 Mureva Phototherapy Inc. Dispositif de photothérapie intra-orale
US11654294B2 (en) 2021-03-15 2023-05-23 Know Bio, Llc Intranasal illumination devices
US11986666B2 (en) 2020-03-19 2024-05-21 Know Bio, Llc Illumination devices for inducing biological effects
US11992696B2 (en) 2022-01-28 2024-05-28 PerioTech, LLC Intraoral phototherapy apparatus and methods for treatment of bruxism
US12011611B2 (en) 2020-03-19 2024-06-18 Know Bio, Llc Illumination devices for inducing biological effects
US12029914B2 (en) 2021-01-13 2024-07-09 Know Bio, Llc Phototherapeutic light for treatment of pathogens

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8241035B2 (en) * 2005-05-25 2012-08-14 Biolase, Inc. Device having activated textured surfaces for treating oral tissue
US20130280671A1 (en) * 2012-04-19 2013-10-24 Biolux Research Ltd. Intra-oral light therapy apparatuses and methods for their use
US20150140502A1 (en) * 2013-10-22 2015-05-21 Biolux Research Ltd. Intra-oral light-therapy apparatuses and methods for their use

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8241035B2 (en) * 2005-05-25 2012-08-14 Biolase, Inc. Device having activated textured surfaces for treating oral tissue
US20130280671A1 (en) * 2012-04-19 2013-10-24 Biolux Research Ltd. Intra-oral light therapy apparatuses and methods for their use
US20150140502A1 (en) * 2013-10-22 2015-05-21 Biolux Research Ltd. Intra-oral light-therapy apparatuses and methods for their use

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11617895B2 (en) 2015-07-28 2023-04-04 Know Bio, Llc Systems and methods for phototherapeutic modulation of nitric oxide
US11524173B2 (en) 2015-07-28 2022-12-13 Know Bio, Llc Systems and methods for phototherapeutic modulation of nitric oxide
CN112105418A (zh) * 2018-05-24 2020-12-18 亥伯龙医疗有限公司 用于生物光子组织治疗的设备
CN112566586A (zh) * 2018-06-08 2021-03-26 阿尔托大学基金会 用于口腔内处理的咬口器及方法
WO2019234308A1 (fr) * 2018-06-08 2019-12-12 Aalto University Foundation Sr Embout buccal et procédé de traitement intra-buccal
USD877340S1 (en) 2018-08-13 2020-03-03 Oral Care Products, Llc Dental mouthpiece for tooth whitening
CN112641529A (zh) * 2019-10-11 2021-04-13 科伊特健康有限公司 用于口腔内治疗的口腔用具和方法
JP2022552665A (ja) * 2019-10-17 2022-12-19 ウェルスメディテック カンパニー，リミテッド マウスピース型治療器
JP7368894B2 (ja) 2019-10-17 2023-10-25 ウェルスメディテック カンパニー，リミテッド マウスピース型治療器
WO2021188279A1 (fr) * 2020-03-19 2021-09-23 Know Bio, Llc Dispositifs d'éclairage pour induire des effets biologiques
US11684798B2 (en) 2020-03-19 2023-06-27 Know Bio, Llc Illumination devices for inducing biological effects
US11752359B2 (en) 2020-03-19 2023-09-12 Know Bio, Llc Illumination devices for inducing biological effects
US11147984B2 (en) 2020-03-19 2021-10-19 Know Bio, Llc Illumination devices for inducing biological effects
US11986666B2 (en) 2020-03-19 2024-05-21 Know Bio, Llc Illumination devices for inducing biological effects
US12011611B2 (en) 2020-03-19 2024-06-18 Know Bio, Llc Illumination devices for inducing biological effects
US12029914B2 (en) 2021-01-13 2024-07-09 Know Bio, Llc Phototherapeutic light for treatment of pathogens
US20220265409A1 (en) * 2021-02-22 2022-08-25 Dustin Lee Cohen Dental devices for simultaneous intra-oral and extra-oral treatments
US11654294B2 (en) 2021-03-15 2023-05-23 Know Bio, Llc Intranasal illumination devices
WO2023039499A1 (fr) * 2021-09-09 2023-03-16 Mureva Phototherapy Inc. Dispositif de photothérapie intra-orale
US11992696B2 (en) 2022-01-28 2024-05-28 PerioTech, LLC Intraoral phototherapy apparatus and methods for treatment of bruxism

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