WO2017197907A1 - Aseptic medication preparation system - Google Patents

Aseptic medication preparation system Download PDF

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Publication number
WO2017197907A1
WO2017197907A1 PCT/CN2017/000362 CN2017000362W WO2017197907A1 WO 2017197907 A1 WO2017197907 A1 WO 2017197907A1 CN 2017000362 W CN2017000362 W CN 2017000362W WO 2017197907 A1 WO2017197907 A1 WO 2017197907A1
Authority
WO
WIPO (PCT)
Prior art keywords
air
solvent
dispensing system
unit
gas
Prior art date
Application number
PCT/CN2017/000362
Other languages
French (fr)
Chinese (zh)
Inventor
张巍
张劲东
Original Assignee
张巍
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN201610329493.2A external-priority patent/CN105796340B/en
Priority claimed from CN201620781461.1U external-priority patent/CN206273281U/en
Priority claimed from CN201620781398.1U external-priority patent/CN206261831U/en
Priority claimed from CN201620781400.5U external-priority patent/CN206275831U/en
Priority claimed from CN201620781399.6U external-priority patent/CN206261832U/en
Priority claimed from CN201720052251.3U external-priority patent/CN208710520U/en
Application filed by 张巍 filed Critical 张巍
Publication of WO2017197907A1 publication Critical patent/WO2017197907A1/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests

Definitions

  • the invention relates to the technical field of medical instruments, in particular to an aseptic dispensing system.
  • the most common way of clinical infusion dispensing is by manual dispensing.
  • the nurse needs to manually mix the liquid medicine, powder and the like in the ampoule with other liquids, and then inject the mixture into the infusion bottle or the patient. .
  • the nurse continuously operates the dispensing device to absorb liquid and inject liquid.
  • the labor intensity is high, the efficiency is low, and the manual operation is easy to make mistakes.
  • the nurse's hand cannot contact the dispensing pusher of the dispensing device, and the operation difficulty is difficult. Big, it is inevitable that there are mistakes, increasing the risk of drug contamination.
  • the technical solution adopted by the present invention is to provide an aseptic dispensing system, comprising: a solvent-dissolving unit for providing a cavity for mixing the medicament;
  • a power unit for powering the solvent unit A power unit for powering the solvent unit.
  • the aseptic dispensing system further comprises a first hand-held component and a sterilization unit, the hand-held component being detachably coupled to the power unit, the sterilization unit for filtering impurities and bacteria in the air .
  • the power unit includes a pipeline group and a first air pump, the first air pump is in communication with the pipeline group, the pipeline group includes at least four pipelines, and the pipeline group includes electromagnetic
  • the solenoid valve group includes at least four solenoid valves, and the number of solenoid valves in the solenoid valve group corresponds to the number of pipelines in the pipeline group.
  • the aseptic dispensing system further comprises a sterile unit for constructing a sterile environment, the sterile unit comprising a dispensing push rod and a set of rods, the dispensing push rod being located in the set rod Internally, and the dispensing push rod and the sleeve rod are relatively movable, the solvent-dissolving unit is in sealing connection with the aseptic unit; the power unit is an actuating portion for driving the dispensing push rod Move forward or backward.
  • a sterile unit for constructing a sterile environment
  • the sterile unit comprising a dispensing push rod and a set of rods, the dispensing push rod being located in the set rod Internally, and the dispensing push rod and the sleeve rod are relatively movable, the solvent-dissolving unit is in sealing connection with the aseptic unit; the power unit is an actuating portion for driving the dispensing push rod Move forward or backward.
  • the aseptic dispensing system further includes a first clean laminar flow device, a purifying device, and a second air pump, the purifying device having one end in communication with the first clean laminar flow device and the other end and the second air pump Connected.
  • the aseptic dispensing system further comprises a second hand-held component, a sterilization device, a second clean laminar flow device, a first magnet and a second magnet; a piston is built in the solvent-dissolving unit, the rubber plug a first magnet is disposed therein; one end of the second hand-held component is detachably connected to the solvent-dissolving unit, the other end is in communication with the power unit, and the second hand-held component is internally provided with a second magnet;
  • the second clean laminar flow device is in communication with the power unit, and the sterilization device is in communication with the power unit.
  • the sterilization device comprises a first sterilization device and a second sterilization device
  • the first sterilization device is disposed inside the second hand-held component
  • the second clean laminar flow device passes through the
  • the second sterilization device is in communication with the pneumatic unit
  • the second magnet is an electromagnet
  • the aseptic dispensing system further includes a first purifying device, a second purifying device, and a third clean laminar flow device, the first purifying device having one end connected to the solvent-dissolving unit; and the second purifying device One end is in communication with the third clean laminar flow device, the other end is in communication with the power unit, a piston is built in the solvent body, a third magnet is disposed inside the piston, and the first purification device is internally provided The fourth magnet.
  • the aseptic dispensing system further comprises a first purifying device, a second purifying device and a fourth clean laminar flow device, the power unit comprising a third air pump and a fourth air pump, the first purifying device having one end The drug dissolution unit is connected, and the other end is in communication with the third air pump; the second purification device has one end communicating with the fourth clean laminar flow device, and the other end is in communication with the fourth air pump, and the piston is built in the The drug dissolver body.
  • the power unit is a gas source output device, comprising:
  • a purifying device for outputting a gentle, small flow of clean air.
  • the present invention provides an aseptic dispensing system in which the power unit is capable of powering a drug dissolution unit, facilitating operation by a user, and improving the efficiency of dissolution of the drug;
  • the solvent-dissolving unit and the first hand-held component are connected by a detachable connection, which is easy to disassemble and convenient to use; the solvent-dissolving unit has low manufacturing cost and is suitable for mass production and popularization.
  • FIG. 1 is a schematic structural view of an aseptic dispensing system according to a first embodiment of the present invention
  • FIG. 2 is a schematic structural view of an aseptic dispensing system according to a second embodiment of the present invention.
  • Figure 3 is a cross-sectional view showing the first hand-held component and the drug-dissolving unit in the second embodiment of the present invention
  • FIG. 4 is a schematic diagram of connection of a control unit in Embodiment 2 of the present invention.
  • Figure 5 is a cross-sectional view showing the first hand-held component and the drug dissolution unit in the third embodiment of the present invention.
  • Figure 6 is a schematic view 1 of the aseptic dispensing system of the present embodiment
  • Figure 7 is a schematic view 2 of the aseptic dispensing system of the present embodiment.
  • Figure 8 is a schematic view 3 of the aseptic dispensing system of the present embodiment.
  • Figure 9 is a schematic view 4 of the aseptic dispensing system of the present embodiment.
  • Figure 10 is a schematic view showing the structure of the aseptic dispensing system in the present embodiment.
  • Figure 11 is a schematic view showing the internal structure of the second hand-held component in the embodiment.
  • Figure 12 is a schematic diagram showing the function of the control unit in the embodiment.
  • Figure 13 is a schematic view showing the structure of the drug dissolver body of the present invention.
  • Figure 14 is a schematic view showing the structure of a solvent dissolver of the aseptic dispensing system of the present embodiment
  • Figure 15 is a schematic view showing the structure of a solvent dissolver of the aseptic dispensing system of the present embodiment
  • Figure 16 is a front elevational view of the gas source output device
  • Figure 17 is a rear elevational view of the gas source output device
  • Figure 18 is a schematic view showing the internal structure of the front side of the gas source output device
  • Figure 19 is a schematic view showing the internal structure of the back side of the air source output device
  • Figure 20 is a schematic diagram of a fan of a gas source output device
  • Figure 21 is a schematic view of the gas flow of the present invention.
  • Figure 22 is an overall appearance view of the fifteenth embodiment
  • Figure 23 is a schematic view showing the flow of gas in the sixteenth embodiment
  • Figure 24 is a schematic view showing the flow of gas in the seventeenth embodiment
  • Figure 25 is a schematic view showing the flow of gas in the eighteenth embodiment
  • Figure 26 is a schematic structural view of Embodiment 19;
  • Figure 27 is a schematic view showing the structure of Embodiment 20.
  • the present invention provides an aseptic dispensing system comprising: a drug dissolution unit for providing a cavity for mixing a medicament; and a power unit for powering the drug dissolution unit.
  • the solvent-dissolving unit has low manufacturing cost and is suitable for mass production and popularization; the power unit can provide power for the drug-dissolving unit, is convenient for the user to operate, and improves the efficiency of the drug-dissolving.
  • the present invention provides an aseptic dispensing system comprising: a drug dissolution unit for providing a cavity for mixing a medicament; a power unit for powering the drug dissolution unit; and a first hand held component for connecting to the a solvent unit and the power unit; a sterilization unit for filtering impurities and bacteria in the air.
  • FIG. 1 is a schematic structural view of the aseptic dispensing system of the first embodiment.
  • the drug dissolution unit 1 is connected to the first hand-held component 3 via a first quick interface 2, and the power unit 4 is connected to the first hand-held component 3 via a second quick interface 5.
  • the sterilization unit 6 is built in the first hand held part 3.
  • the solvent-dissolving unit comprises a drug dissolver body 11, an injection needle 12, a needle holder 13 and a first piston 14.
  • One end of the drug dissolver body 11 is connected to the injection needle 12 through a needle holder 13, and the other end of the drug dissolver body 11 is provided.
  • the first piston 14 is built in the solvent body 11 at the first pair of interfaces 15 that connect the first quick interface 2.
  • the needle holder 13 is a hollow column that is outwardly convex relative to the body of the dissolver for supporting the injection needle 12, and the injection needle 12 is fixed in the needle holder 13 by a fixing unit, the fixing The unit may be an elastomer having a sealing function such as a rubber soft body or a resin soft body.
  • the inner surface of the drug dissolver body 11 has a cylindrical shape, and the first piston 14 is a cylindrical rubber soft body, and the outer diameter of the first piston 14 is the same as the inner diameter of the solvent body 11.
  • the first piston 14 moves axially within the solvent body 11.
  • the first piston 14 separates the interior of the solvent body 11 into a solvent chamber 16 and a solvent chamber, and the solvent chamber 16 and the solvent chamber 17 are completely hermetically sealed.
  • the first hand-held component 3 includes a housing 31 and a second piston 32.
  • One end of the housing 31 is provided with a first quick interface 2, and the other end of the housing 31 is provided with a second quick interface 5.
  • the second piston 32 is built in the housing 31.
  • the material used to make the second piston 32 is a high temperature resistant and biosafety silicone rubber.
  • the inner surface of the casing 31 has a cylindrical shape
  • the second piston 32 is a cylindrical rubber soft body
  • the outer diameter of the second piston 32 is the same as the inner diameter of the casing 31.
  • the second piston 32 moves axially within the housing 31.
  • the sterilization unit 6 includes a sterilization device 61, and the sterilization device 61 is installed inside the casing 31.
  • the sterilization device 61 comprises at least one of polypropylene, diatomaceous earth, glass fiber, mixed cellulose ester, polyvinylidene fluoride, polytetrafluoroethylene, polyether oxime, nylon, cellulose ester, and modified cellulose.
  • the filtration pore size of the sterilization device 61 does not exceed 0.22 micrometers.
  • the sterilization device 61 and the second piston 32 collectively divide the housing 31 into a first air chamber 33, a second air chamber 34, and a third air chamber 35, and the first air chamber 33 is located at the Between the second piston 32 and the second quick interface 5, the second air chamber 34 is located between the second piston 32 and the sterilization device 61, and the third air chamber 35 is located at the sterilization device 61 is between the first fast interface 2.
  • the first air chamber 33 and the second air chamber 34 are completely hermetically sealed, and the second air chamber 34 and the third air chamber 35 are in communication with each other through the sterilization device 61.
  • the gas pressures in the solvent chamber, the second chamber 34, and the third chamber 35 are the same.
  • the power unit 4 includes a first air pump 41 and a gas pump switch 42, and the first air pump 41 is provided with a second pair of interfaces 43 for connecting the second quick interface 5.
  • the first air pump 41 is in communication with the first air chamber 33 through the second quick interface 5 .
  • the air pump switch 42 is provided with a standby gear position, an inflation gear position and an exhaust gear position.
  • the operation of the first air pump 41 provides two modes of operation, the mode of operation including a pressurization process and a depressurization process.
  • the pressurization process is:
  • the air pump switch 42 is adjusted to the inflating gear position, and the first air pump 41 pumps air into the first air chamber 33 to increase the air pressure in the first air chamber 33.
  • the air pressure in the first air chamber 33 is higher than the second air chamber 33
  • the air chamber 34 is in the air chamber 34, the high pressure gas in the first air chamber 33 pushes the second piston 32 to move away from the first air pump 41, and the gas in the second air chamber 34 gradually flows into the third air chamber 35 through the sterilization device 61. Therefore, the air in the third air chamber 35 is filtered sterile air.
  • the third air chamber 35 communicates with the solvent chamber 17 through the first quick interface 2, the gas in the third air chamber 35 gradually flows into the solvent chamber 17 of the solvent, and the gas pressure in the air chamber 17 of the solvent is higher than that.
  • the pressure in the drug chamber 16 causes the high pressure gas in the solvent chamber 17 to urge the first piston 14 toward the needle holder 13.
  • the air pump decompression process is:
  • the air pump switch 42 is adjusted to the exhaust gear position, the first air pump 41 pumps the air in the first air chamber 33, the air pressure in the first air chamber 33 is lowered, and the air pressure in the first air chamber 33 is low.
  • the high pressure gas in the second air chamber 34 pushes the second piston 32 to move toward the first air pump 41, so that the gas in the third air chamber 35 gradually flows into the second air chamber 34, and then dissolves.
  • the gas in the drug chamber 17 flows into the third air chamber 35.
  • the air pressure in the solvent chamber 17 is lower than the pressure in the solvent chamber 16, the first piston 14 moves away from the needle holder 13. .
  • the working principle of the aseptic dispensing system is:
  • the second pair of interfaces 43 are connected to the second quick interface 5, and then the first pair of interfaces 15 are connected to the first quick interface.
  • the air pump switch 42 is adjusted to the inflated gear position, and the first increase is performed.
  • the air in the solvent chamber 16 is completely discharged.
  • the injection needle 12 is inserted into the liquid medicine bottle, and then the air pump switch 42 is adjusted to the exhaust gear position, and execution is performed.
  • the drug solution flows into the drug dissolution chamber 16, and then the liquid drug bottle is removed, and the injection needle 12 is inserted into the lyophilized powder drug bottle, thereby performing a second pressurization process to make the drug solution chamber 16
  • the medicine liquid flows into the lyophilized powder medicine bottle, and after the medicine liquid and the lyophilized powder are thoroughly mixed, the second decompression process is performed, and the mixture of the lyophilized powder and the medicine liquid is extracted into the solvent cavity. Complete the dissolution.
  • the air in the solvent chamber 17 is always kept as sterile air after filtration, preventing the interior of the solvent body 11 from being contaminated, and making the solvent-dissolving process safer.
  • the present embodiment provides an aseptic dispensing system comprising: a drug dissolution unit for providing a cavity for mixing a medicament; a power unit for powering the drug dissolution unit; and a first hand-held component for connecting The solvent unit and the power unit; a sterilization unit for filtering impurities and bacteria in the air; and a control unit for controlling the power unit.
  • FIG. 2 is a schematic view showing the structure of the aseptic dispensing system in the second embodiment.
  • the solvent-dissolving unit 101 is screwed to the first hand-held component 102, the sterilization unit is connected to the power unit 103, and the power unit 103 is connected to the first hand-held component 102 through a gas pipe 104.
  • the control unit 105 is connected to the first hand-held component 102 and the power unit 103 by wires, and the control unit 105 is used to control the power unit 103.
  • the drug dissolution unit 101 includes a drug dissolver body 111, an injection needle 112, a needle holder 113, and a first piston 114.
  • the front end of the drug solution body 111 is connected to the injection needle 112 through the needle holder 113.
  • the tail end of the dissolver body 111 is screwed to the first hand-held component 102, and the first piston 114 is built in the solvent body 111.
  • the needle holder 113 is a hollow column that is outwardly convex relative to the drug sol body for supporting the injection needle 112.
  • the injection needle 112 is fixed in the needle holder 113 by a fixing unit.
  • the fixing unit may be an elastomer having a sealing function such as a rubber soft body or a resin soft body.
  • the inner surface of the solvent body 111 is cylindrical, the first piston 114 is a cylindrical rubber soft body, and the outer diameter of the first piston 114 is the same as the inner diameter of the solvent body 111.
  • the first piston 114 moves axially within the solvent body 111.
  • the first piston 114 separates the interior of the solvent body 111 into a solvent chamber 116 and a solvent chamber 117, and the solvent chamber 116 and the solvent chamber 117 are completely hermetically sealed.
  • the first hand-held component 102 includes a handle 121 and a handle base 122.
  • One end of the handle 121 is connected to the handle base 122 by a first thread 123, and the other end of the handle 121 is connected to the air tube 104 via a pneumatic joint 124.
  • the handle 121 further includes a push button 125 and a suction button 126, and the push button 125 and the suction button 126 control the power unit 103 through the control unit 105.
  • the handle base 122 is internally provided with a second thread 127 for fixing the tail end of the solvent body 111 to the handle seat 122.
  • the handle base 122 further includes a sealing pad 128, and the sealing pad 128 is disposed between the solvent body 111 and the handle seat 122 for securing the solvent body 111 and the The airtightness of the connection between the handle seats 122.
  • the handle 121 is an internal hollow structure.
  • the power unit 103 includes a connection tee 130, a first pipeline 131, a second pipeline 132, a third pipeline 133, a fourth pipeline 134, an air pump 135, a gas pump intake tee 136, and a gas pump exhaust tee. 137.
  • the first line 131 includes a first solenoid valve 1311, a first line front section 1312, and a first line rear section 1313.
  • the first pipeline front section 1312 and the first pipeline rear section 1313 are connected by the first solenoid valve 1311.
  • the second conduit 132 includes a second solenoid valve 1321, a second conduit front section 1322, and a second conduit rear section 1323.
  • the second pipeline front section 1322 and the second pipeline rear section 1323 are connected by a second electromagnetic valve 1321.
  • the third conduit 133 includes a third solenoid valve 1331, a third conduit front section 1332, and a third conduit rear section 1333.
  • the third pipeline front section 1332 and the third pipeline rear section 1333 are connected by a third solenoid valve 1331.
  • the fourth conduit 134 includes a fourth solenoid valve 1341, a fourth conduit front section 1342, and a fourth conduit rear section 1343.
  • the fourth pipeline front section 1342 and the fourth pipeline rear section 1343 are connected by a
  • the air pump 135 includes a gas pump intake port 1351 and a gas pump exhaust port 1352.
  • the three ports of the air pump intake tee 136 are respectively connected to the air pump inlet 1351, the first pipeline rear section 1313 and the second pipeline rear section 1323.
  • the three ports of the air pump exhaust tee 137 are respectively connected to the air pump exhaust port 1352, the third pipeline rear section 1333 and the fourth pipeline rear section 1343.
  • the three ports connecting the three-way 130 are connected to the air pipe 104, the second pipe front section 1322, and the third pipe front section 1332, respectively.
  • the sterilization unit is a filter, and the filter is disposed on the air inlet 141 and the air outlet 142, that is, under the action of the filter, the air inlet 141 and the air outlet 142 have both intake air and air outlet. Filtering the function of sterilization, the air inlet 141 is connected to the first pipeline front section 1312, and the exhaust port 142 and the fourth pipeline front section 1342 connection.
  • the filter disposed on the air inlet 141 and the exhaust port 142 includes at least polypropylene, diatomaceous earth, glass fiber, mixed cellulose ester, polyvinylidene fluoride, polytetrafluoroethylene, polyethersulfone, One of nylon, cellulose ester, and modified cellulose.
  • the filter apertures of the filters on the inlet 141 and the outlet 142 are each no more than 0.22 microns.
  • the sterilization unit causes the gas entering the air pump 135 and the interior of the solvent chamber 117 to be sterile air.
  • control unit is connected to the air pump 135, the push button 125, the suction button 126, the first solenoid valve 1311, the second solenoid valve 1321, and the third.
  • the solenoid valve 1331 is connected to the fourth solenoid valve 1341.
  • the first control logic executed by the control unit 105 is that after the push button 125 is pressed separately, the first solenoid valve 1311 and the third solenoid valve 1331 are opened, the second solenoid valve 1321 and the fourth solenoid valve 1341 are closed, and the air pump 135 is closed. start working.
  • the first control logic is executed to sequentially pass air through the air inlet 141, the first pipeline front section 1312, the first solenoid valve 1311, the first pipeline rear section 1313, the air pump intake tee 136, and the air pump inlet 1351.
  • the cavity 117 when the pressure in the solvent chamber 117 is greater than the solvent chamber 116, the high pressure gas in the solvent chamber 117 pushes the first piston 114 to move away from the handle 121.
  • the second control logic executed by the control unit 105 is that after the suction button 126 is separately pressed, the first electromagnetic valve 1311 and the third electromagnetic valve 1331 are closed, and the second electromagnetic valve 1321 and the fourth electromagnetic valve 1341 are opened.
  • the air pump 135 starts working.
  • the second control logic is executed to sequentially pass the gas in the solvent chamber 117 through the inside of the handle 121, the air tube 104, the connection tee 130, the second line front section 1322, the second solenoid valve 1321, and the second line.
  • the tail end of the solvent body 111 is fixedly connected with the handle base 122, and then the push button 125 is pressed to execute the first control logic to discharge all the air in the solvent chamber 116.
  • the push button 125 is released, and the injection needle 112 is inserted into the liquid drug bottle, and then the suction button 126 is pressed to execute the second control logic, after the drug solution flows into the drug solution chamber 116.
  • Release the push button 126 remove the liquid medicament bottle, insert the needle 112 into the lyophilized powder bottle, and press the push button 125 to execute the first control logic to allow the drug solution into the drug solution chamber 116 to flow into the drug solution.
  • the suction button 126 is pressed to execute the second control logic, and the mixture of the lyophilized powder and the medicine liquid is extracted into the solvent cavity to complete the dissolution medicine. .
  • the air in the solvent chamber 117 is always kept as sterile air after filtration, preventing the interior of the solvent body 111 from being contaminated, and making the solvent-dissolving process more secure.
  • the present embodiment provides an aseptic dispensing system that differs from the second embodiment in that a sterilization unit is built in the first hand-held component 202, that is, the air inlet 141 and the air outlet 142 are only It has an intake and exhaust function, and its hand held component 102 also includes a second piston 223.
  • the second piston 223 is built in the handle 221 .
  • the material used to make the second piston 223 is a high temperature resistant and biosafety silicone rubber.
  • the inner surface of the handle 121 has a cylindrical shape
  • the second piston 223 is a cylindrical rubber soft body
  • the outer diameter of the second piston 223 is the same as the inner diameter of the handle 121.
  • the second piston 223 moves axially within the handle 121.
  • the sterilization unit is built in the handle 121.
  • the sterilization unit is a filter 206, and the filter 206 comprises at least polypropylene, diatomaceous earth, glass fiber, mixed cellulose ester, polyvinylidene fluoride, polytetrafluoroethylene, polyether oxime, nylon, cellulose ester, improved In one of the celluloses, the filter 206 has a filtration pore size of no more than 0.22 microns.
  • the filter 206 and the second piston 223 collectively divide the handle 121 into a first air chamber 2211, a a second air chamber 2212, a third air chamber 2211, the first air chamber 2211 is located between the second piston 223 and the pneumatic joint 124, and the second air chamber 2212 is located at the second piston 223 and the filter Between the 206, the third air chamber 2213 is located between the filter 206 and the handle base 122.
  • the first air chamber 2211 and the second air chamber 2212 are completely hermetically sealed, and the second air chamber 2212 and the third air chamber 2213 are in communication with each other through the filter 206.
  • the gas pressures in the solvent chamber 117, the second chamber 2212, and the third chamber 2213 are the same.
  • the air is sequentially flowed through the air inlet 141, the first pipeline front section 1312, the first solenoid valve 1311, the first pipeline rear section 1313, the air pump intake tee 136, and the air pump inlet 1351.
  • the air pressure in the first air chamber 2211 is increased.
  • the air pressure in the first air chamber 2211 is higher than the second air chamber 2212, the high pressure gas in the first air chamber 2211 pushes the second piston 223 to move away from the air pump 135.
  • the movement of the second piston 223 causes the gas in the second air chamber 2212 to gradually flow into the third air chamber 2213 through the filter 206, so that the air in the third air chamber 2213 is filtered sterile air. Since the third air chamber 2213 communicates with the solvent chamber 117 through the handle seat 122, the gas in the third air chamber 2213 gradually flows into the solvent chamber 117, and the gas pressure in the solvent chamber 117 is higher than that in the solvent chamber 117. During the pressure within the drug chamber 116, the high pressure gas within the solvent chamber 117 will urge the first piston 114 toward the needle holder 113.
  • the air pump 135 starts to operate, so that the gas in the first air chamber 2211 sequentially flows through the air pipe 104, the connection tee 130, the second pipeline front section 1322, the second solenoid valve 1321, and the second pipeline.
  • the gas in the second air chamber 2212 pushes the second piston 223 toward the air pump 135.
  • the gas in the third air chamber 2213 is gradually flowed into the second air chamber 2212, and then the gas in the solvent chamber 117 flows into the third air chamber 2213.
  • the gas pressure in the solvent chamber 117 is lower than the solvent chamber
  • the first piston 114 moves away from the needle holder 113.
  • a sterile unit for constructing a sterile environment, the sterile unit comprising a dispensing push rod and a set of rods, the dispensing push rod being located in the set rod;
  • the solvent unit is in a sealed connection with the sterile unit.
  • the aseptic dispensing system also includes a first clean laminar flow device, a purification device, and a second air pump.
  • the sterile unit includes a dispensing push rod and a set of rods, the dispensing push rod is located in the set rod; the sterile unit may be a disposable component, and in order to prevent bacteria from entering the solvent-dissolving unit, a set of rods is disposed outside the dispensing pusher connected to the solvent-dissolving unit, so that the dispensing push rod is in a sterile environment; the dispensing push rod is fixed inside the sleeve by a fixing member, the fixing member The fixed form can be fixed at both ends or screwed. Among them, the dispensing pusher is the front pusher 410.
  • the drug dissolution unit includes a drug dissolver body 11 and a rubber stopper 21 having a cavity formed by a gap between the drug dissolver body 11 and the rubber stopper 21
  • the size of the cavity may vary depending on the relative position of the dissolver body 11 and the rubber stopper 21.
  • the power unit is an actuating portion, and the actuating portion comprises: a push rod motor 310, a push rod gear 311, a rotating support ring 312 and an external thread push rod 313.
  • the push rod motor 310 is used to power the actuating portion, and the push rod motor 310 as a power mechanism may be a step linear motor, a permanent magnet linear motor, and any other type of linear motor; the push rod gear 311 Connected to the push rod motor 310, the push rod gear 311 is used to transmit the power provided by the push rod motor 310 to a subsequent unit; the rotating support ring 312 has a toothed structure on the outside, the rotating support ring The outer toothed structure of the 312 meshes with the teeth of the push rod gear 311, and the inner side of the rotating support ring 312 is internally provided Threaded, the rotating support ring 312 is fixed by the outer structure, so that the rotating support ring 312 can only pivot under the driving of the push rod gear 311, and can not perform translation in all directions, the external thread pushing A rod 313 is placed inside the rotating support ring 312, and an external thread of the externally threaded push rod 313 cooperates with an internal thread of the rotating support ring 312.
  • the push rod motor 310 rotates to drive the push rod gear 311 connected thereto to rotate, and the push rod gear 311 rotates to further rotate the rotating support ring 312 engaged with the rotating support ring 312 only in the push rod gear.
  • the rotation of the shaft 311 is not able to perform translation in all directions, and the rotation of the rotation support ring 312 will drive the external thread push rod 313 to move in the axial direction.
  • the joint portion includes: a gear set, a head rotating electric machine 413, a parallel rail 414 and a support ring 415;
  • the gear set includes a first gear 411 and a second gear 412;
  • the joint portion is driven by the external thread push rod 313, and the end portion of the external thread push rod 313 is connected to one side of the first gear 411, and the first gear 411 is moved in the axial direction along with the external thread push rod 313.
  • the first gear 411 is movably connected with the externally-threaded push rod 313, that is, the first gear 411 is rotatable relative to the externally-threaded push rod 313; the other side of the first gear 411 is connected to one end of the front-stage push rod 410, first The gear 411 drives the front push rod 410 to rotate and rotate coaxially.
  • the other end of the front push rod 410 is provided with an internal thread, and the rubber plug 21 is provided with an externally threaded joint 210 corresponding to the internal thread on the front push rod 410.
  • the support ring 4 is disposed outside the front stage push rod 410.
  • the head rotating electric machine 413 is configured to provide a rotating torque to the front stage push rod 410 to screw the front stage push rod 410 with the externally threaded joint 210 on the rubber plug 21, the head rotation
  • the motor 413 is coupled to the second gear 412, the second gear 412 is meshed with the first gear 411; the head rotating motor 413 is slidable along the parallel rail 414 when the front section push rod When the shaft 410 is translated in the axial direction, the head rotating electric machine 413 slides synchronously along the parallel rails 414.
  • the externally-threaded push rod 313 When the externally-threaded push rod 313 is moved in the axial direction by the rotation support ring 312, the externally-threaded push rod 313 drives the front-stage push rod 410 to move, and at the same time, the actuating portion drives the
  • the head rotating electric machine 413 slides synchronously with the front stage push rod 410 along the parallel rail 414; in the initial state, the front stage push rod 410 is at the distal end position of the solvent body 11 at this time, The front push rod 410 does not protrude into the interior of the solvent body 11.
  • the rubber plug 21 is located at the foremost end of the solvent body 11, and the front push rod is driven by the external thread push rod 313. 410 gradually extends into the interior of the solvent body 11.
  • the head rotating motor 413 When the front push rod 410 is in contact with the external threaded joint 210 on the rubber plug 21, the head rotating motor 413 is activated, thereby driving the The second gear 412 rotates, the second gear 412 rotates to drive the first gear 411 meshing with the first gear 411, the first gear 411 drives the front push rod 410 to rotate, and the front push rod 410 rotates Rotating around the axis to advance the internal thread of the front push rod 410 Male connector 210 screwed, said front case pusher 41 021 combined with the plug.
  • the push rod motor 310 is reversely rotated, so that the push rod motor 310 drives the push rod gear 311 to rotate in the reverse direction, and the rotating support ring 312 that meshes with the push rod gear 311 rotates in the reverse direction, thereby causing the externally threaded push rod 313 to
  • the internal thread of the rotating support ring 312 is driven in the opposite direction, and the externally-threaded push rod 313 drives the first gear 411 to move in the opposite direction.
  • the first gear 411 drives the front-stage push rod 410 toward the far-dissolving body 11 .
  • the direction movement, the front push rod 410 drives the rubber plug 21 combined with it to move away from the solvent body 11 , and then completes the suction process through the needle disposed at the front of the dissolver body 11; the solvent body 11 can be connected to a needle.
  • the first clean laminar flow device 514 is disposed above the side of the push rod 34 that is adjacent to the first gear 411.
  • An annular air outlet is disposed on the first clean laminar flow device 514, and the first clean laminar flow device 514 is in communication with the purifying device 516 through the air tube 515.
  • the purifying device 516 is provided with an air filter 517, and the air filter 517 is used for filtering from the second The gas of the air pump 518, the second air pump 518 is in communication with the purification device 516 via a conduit.
  • the second air pump 518 pumps air into the purification device 516, and the air is filtered by the air filter 517 in the purification device 516 to form sterile air, which in turn flows through the air tube 515 and the first clean. Laminar flow device 514.
  • the filtered sterile air is discharged through an annular vent on the first clean laminar flow device 514, and the sterile air forms a positive pressure at the annular vent.
  • the sterile air forming a positive pressure surrounds the solvent body 11 and the needle to form a gas shield laminar flow, and the gas shield laminar flow can avoid the dissolver body 11 Contact with the air with bacteria to enhance the safety of the dispensing.
  • the present invention provides an aseptic dispensing system that differs from the fourth embodiment in that the front end push rod 410 is provided with an external thread at one end, and the rubber end 21 is provided with the front end push rod 410. Corresponding internal threaded joint; the front push rod 410 rotates about the axis while advancing, and the external thread of the front push rod 410 is screwed with the female threaded joint of the rubber plug 21, thereby The front stage push rod 410 is combined with the rubber plug 21.
  • An aseptic dispensing system provided by this embodiment is different from Embodiment 5 in that the aseptic dispensing system is further provided with a plurality of photoelectric position sensors, and a photoelectric block that can move along with the joint portion.
  • the sheet 610 through the cooperation of the photoelectric position sensor and the photoelectric blocking piece 610, can realize the opening and closing of the circuit to control the rotation of the push rod motor 310 and the head rotating electric machine 413; as shown in FIG.
  • the photoelectric blocking piece 610 is induced by the first photoelectric position sensor 510, the front stage push rod 410 is at a farthest position from the solvent body 11 , and the front stage push rod 410 does not protrude into the solvent.
  • the rubber plug 21 is located at the foremost end of the solvent body 11; as shown in FIG. 7 , the front push rod 410 is gradually extended by the actuating portion.
  • the front stage push rod 410 is in contact with the tail end of the male threaded joint 210 disposed on the rubber plug 21 , At this time, the head rotating electric motor 413 is activated, thereby driving The front pusher 410 rotates; as shown in FIG.
  • the pusher motor 310 continues to push the front pusher 410 forward, while the head rotary motor 413 drives the front pusher 410 to rotate, the front push The rod 410 rotates about the axis while advancing, and the external thread of the front push rod 410 is screwed with the female threaded joint of the rubber plug 21, so that the front push rod 410 is combined with the rubber plug 21,
  • the photoelectric blocking piece 610 is sensed by the fourth photoelectric position sensor 513
  • the front stage push rod 410 is screwed and fixed to the external threaded joint 210, and the front stage push rod 410 reaches the foremost position of the stroke; As shown in FIG.
  • the sterile dispensing system provided in this embodiment is different from the embodiment 6 in that the aseptic dispensing system further comprises:
  • a main control circuit configured to receive a signal transmitted by the photoelectric blocking piece 610 and the photoelectric position sensor, and control start and stop of the head rotating electric machine 413 and the push rod motor 310;
  • a status indicator light for displaying the working status of the aseptic dispensing system, prompting the medical personnel to perform reasonable operations.
  • An aseptic dispensing system provided in this embodiment is different from the embodiment 7 in that, in actual use, in order to ensure that the dispensing system is in a sterile state and avoid doping of different agents, the solvent body 11
  • Both the rubber plug 21 can be designed as a detachable disposable component, which can also be designed as a detachable disposable component.
  • the portion of the sterile dispensing system that is easily contaminated can be made into a disposable structure, such as the solvent body 11 and the glue, in a form in which the front pusher 410 is screwed into the rubber plug 21
  • the plug 21; the non-contaminated portion is used for multiple times, such as the front push rod 410; other parts that are not in contact with the liquid medicine are used for a long period of time and are periodically disinfected.
  • the degree of waste of the disposable component can be saved, and only the solvent body 11 and the rubber plug 21 need to be replaced after each use, without The front pusher 410 is replaced each time, thereby reducing medical waste and protecting the environment.
  • An aseptic dispensing system provided in this embodiment is different from the embodiment 8 in that the dispensing pusher is a non-detachable component; the dispensing pusher is fixedly connected to the actuating portion, and the dispensing pusher External setting The sleeve is sealingly coupled to the actuation portion to ensure that the sterile unit is in a sterile environment at all times.
  • FIG. 10 is a schematic structural view of the aseptic dispensing system of the present invention.
  • FIG. 11 is a schematic view showing the internal structure of the second hand-held component in the present invention.
  • FIG. 12 is a schematic view showing the function of the control unit in the present invention. .
  • the present invention provides an aseptic dispensing system comprising: a drug dissolution unit for providing a cavity for mixing a medicament; and a second clean laminar flow device for placing the drug dissolution unit in a sterile environment; a power unit for powering the solvent-dissolving unit and providing a positive pressure gas for the second clean laminar flow device; a second hand-held component for connecting the solvent-dissolving unit and the power unit; and a control unit For controlling the power unit; the sterilization device, the sterilization device includes a first sterilization device 407 and a second sterilization device 9.
  • the solvent-dissolving unit includes a drug dissolver body 11 that is screwed to the second hand-held component 40, the power unit is an air pump 7, and the second hand-held component 40 is in communication with the air pump 7 through the first air pipe 602.
  • the control unit 8 is electrically connected to the second hand-held component 40 and the air pump 7, respectively.
  • the drug dissolution unit further includes an injection needle 22, a needle holder 110 and a rubber stopper 21, and the front end of the drug solution body 11 is connected to the injection needle 22 through the needle holder 110, and the tail end of the drug dissolver body 11 and the first
  • the two hand-held members 40 are screwed together, and the rubber stopper 21 is built in the solvent body 11.
  • the needle holder 110 is a hollow column that is outwardly convex relative to the body of the drug solution for supporting the injection needle 22.
  • the injection needle 22 is fixed in the needle holder 110 by a fixing unit, and the fixing unit can be a rubber soft body.
  • An elastomer having a sealing function such as a resin soft body.
  • the inner surface of the drug dissolver body 11 has a cylindrical shape, one end of the rubber plug 21 is a cylindrical rubber soft body, and the other end is provided with a first magnet, the first magnet is a permanent magnet 2101, the outer diameter of the rubber plug 21 and the solvent body 11 inner diameter is the same.
  • the rubber stopper 21 moves axially within the dissolver body 11.
  • the rubber plug 21 separates the inside of the solvent body 11 into a solvent cavity 120 and a solvent cavity 140, and the solvent cavity 120 and the solvent cavity 140 are completely sealed.
  • the second hand held component 40 includes a handle base 405 and a handle 406. One end of the handle 406 is coupled to the handle base 405 by a first thread 50, and the other end of the handle 406 is coupled to the first air tube 602 by a pneumatic joint 403.
  • the first button and the second button are further disposed on the handle 406.
  • the first button is a push button 401
  • the second button is a suction button 402
  • the push button 401 and the suction button 402 are electrically connected to the control unit 8.
  • the handle seat 405 is internally provided with a second thread 404 for securing the trailing end of the solvent body 11 to the handle seat 405.
  • the handle base further includes a sealing rubber pad 502 disposed between the drug dissolver body 11 and the handle seat 405 for ensuring the airtightness of the connection between the drug dissolver body 11 and the handle seat 405.
  • the handle 406 is an internal hollow structure.
  • a first sterilization device 407 and a second magnet are also disposed inside the handle 406.
  • the sterilization material used in the first sterilization device 407 includes at least polypropylene, diatomaceous earth, glass fiber, mixed cellulose ester, polyvinylidene fluoride, polytetrafluoroethylene, polyether oxime, nylon, cellulose ester, One or more of the modified cellulose, the filtration pore size of the first sterilization device 407 does not exceed 0.22 ⁇ m.
  • the second magnet is an electromagnet 408 that is electrically connected to the control unit 8.
  • the second clean laminar flow device 501 is disposed on the second hand-held component 40.
  • the second clean laminar flow device 501 is provided with an annular air outlet, and the second clean laminar flow device 501 is connected to the air pump 7 through the second air pipe 601.
  • the second air pipe A second sterilization device 9 and a second electromagnetic valve 603 are also disposed on the 601.
  • the sterilization material used in the second sterilization device 9 includes at least polypropylene, diatomaceous earth, glass fiber, mixed cellulose ester, polyvinylidene fluoride, polytetrafluoroethylene, polyether oxime, nylon, cellulose ester.
  • One or more of the modified cellulose, the filtration pore size of the second sterilization device 9 is not more than 0.22 ⁇ m, and the second sterilization device 9 is for filtering the gas from the air pump 7.
  • the second solenoid valve 603 is electrically connected to the control unit 8.
  • the second hand-held component 40 is in communication with the air pump 7 through the first air tube 602.
  • the first air tube 602 is provided with a first electromagnetic valve 604, and the first electromagnetic valve 604 is electrically connected to the control unit 8.
  • the control unit 8 is electrically connected to the first electromagnetic valve 604, the second electromagnetic valve 603, the air pump 7, the electromagnet 408, the push button 401, and the suction button 402, respectively.
  • the tail end of the dissolver body 11 is fixedly coupled with the handle base 405, and then the push button 401 is pressed.
  • the control unit 8 controls the first solenoid valve 604 and the second solenoid valve 603 to be opened, and the control unit 8 controls The air pump 7 starts to operate, and the air pump 7 starts pumping gas into the first air tube 602 and the second air tube 601.
  • the gas entering the second gas pipe 601 passes through the second electromagnetic valve 603 and the second sterilization device 9, and finally passes through the second
  • the annular air outlet on the clean laminar flow device 501 is discharged, and the gas flowing through the second sterilization device 9 is filtered to become a sterile gas, so that the gas discharged from the annular air outlet on the second clean laminar flow device 501 is none.
  • the sterile air forms a positive pressure at the annular vent.
  • the sterile air forming a positive pressure surrounds the solvent body 11 and the drug taker 2 to form a gas shield laminar flow, and the gas shield laminar flow can prevent the solvent body 11 and the injection needle 22 from contacting the air with bacteria, enhancing The safety of dispensing.
  • the gas entering the first gas pipe 602 flows through the first electromagnetic valve 604 and the first sterilization device 407, and then flows into the solvent chamber 140, so that the gas pressure in the solvent chamber 140 is raised.
  • the gas pressure in the solvent chamber 140 is greater than the pressure in the solvent chamber 12
  • the high pressure gas in the solvent chamber 140 pushes the rubber stopper 21 to move away from the air pump 7, and the rubber plug 21 moves away from the air pump 7
  • the directional movement discharges all the air in the solvent chamber 120.
  • the injection needle 22 is inserted into the liquid medicine bottle, and then the suction button 402 is pressed.
  • control unit 8 controls the first The second solenoid valve 603 is opened, the first electromagnetic valve 604 is closed, the air pump 7 starts to pump the gas into the second gas pipe 601, and the gas entering the second gas pipe 601 passes through the second electromagnetic valve 603 and the second sterilization device 9, and finally passes through the first The annular air outlet on the second clean laminar flow device 501 is discharged.
  • the control unit 8 controls the electromagnet 408 to be energized, and the energized electromagnet 408 generates an electromagnetic field which causes an attractive force between the electromagnet 408 and the permanent magnet 2101 in the rubber stopper 21, and under the action of the magnetic force, the rubber stopper 21 moves toward the electromagnet 408, thereby causing the liquid medicine in the liquid medicine bottle to flow into the drug solution chamber 120, then removing the liquid medicine bottle, inserting the injection needle 22 into the freeze-dried powder freeze-dried powder medicine bottle, and then pressing The button 401 is pushed, at which time the control unit 8 controls the first solenoid valve 604 and the second solenoid valve 603 to be opened, and the air pump 7 pumps the gas into the first gas pipe 602 and the second gas pipe 601.
  • the gas entering the second gas pipe 601 is sequentially passed through the second electromagnetic valve 603 and the second sterilization device 9, and finally discharged through the annular air outlet on the second clean laminar flow device 501.
  • the gas entering the first gas pipe 602 flows through the first electromagnetic valve 604 and the first sterilization device 407, and then flows into the solvent chamber 140, so that the gas pressure in the solvent chamber 140 is raised.
  • the high pressure gas in the solvent chamber 140 pushes the rubber stopper 21 to move away from the air pump 7, so that the solvent is dissolved in the solvent chamber 120.
  • the liquid flows into the lyophilized powder medicament bottle.
  • the suction button 402 is pressed.
  • the control unit 8 controls the second solenoid valve 603 to open, the first solenoid valve 604 is closed, and the air pump 7 starts.
  • the gas is pumped into the second gas pipe 601, and the gas entering the second gas pipe 601 is sequentially passed through the second electromagnetic valve 603 and the second sterilization device 9, and finally discharged through the annular air outlet on the second clean laminar flow device 501.
  • control unit 8 controls the electromagnet 408 to be energized, and the energized electromagnet 408 generates an electromagnetic field which causes an attractive force between the electromagnet 408 and the permanent magnet 2101 in the rubber stopper 21, and under the action of the magnetic force, the rubber stopper 21 moves toward the electromagnet 408, and the mixture of the lyophilized powder and the medical solution is drawn into the dissolution chamber 120 to complete the dissolution.
  • the air in the solvent chamber 12 is always kept as sterile air after filtration, preventing the interior of the body 11 from being contaminated, making the dissolution process safer, and at the same time, the second clean layer
  • the positive pressure of the sterile gas is always output at the annular outlet of the flow device 501, so that the gas shield laminar flow is always present, so that the dissolver body 11, the injection needle 22 and the medicament bottle are in a sterile environment.
  • An aseptic dispensing system provided in this embodiment is different from the embodiment 8 in that the sterilization device includes only a third sterilization device, and the third sterilization device passes through the air tube and the first electromagnetic valve respectively. 604 is in communication with the second solenoid valve 603, and the other end of the third sterilization device is coupled to the power unit.
  • FIG. 13 is a schematic view showing the structure of the drug dissolver body of the present invention.
  • Fig. 14 it is a schematic structural view of a solvent dissolver of the aseptic dispensing system of the present embodiment.
  • the present embodiment provides an aseptic dispensing system comprising a drug dissolver body 11 having a first connecting portion 118 at one end and a second connecting portion 119 at the other end.
  • the first connecting portion 118 is connected to the first cleaning device 51 by a screw connection or a snap connection or a claw hook connection or a screw connection or a magnetic connection.
  • the second connecting portion 119 is connected to the injection needle 22 by a screw connection or a snap connection or a claw hook connection or a screw connection or a magnetic connection.
  • the rubber stopper 21 is built in the solvent body 11.
  • a first magnet is disposed inside the rubber plug 21, and the first magnet is a permanent magnet 2101, and the rubber plug 21 moves axially within the solvent body 11.
  • the rubber stopper 21 divides the drug dissolver body 11 into a first cavity 150 and a second cavity 160.
  • the shape of the drug dissolver body 11 is a cylinder or an elliptical cylinder or a rectangular parallelepiped or a triangular prism.
  • the first purification device 51 communicates with the outside air through the pipe port 52, and the first purification device 51 is further provided inside.
  • the gas line 53 is provided with a pipe port 52 at one end and a second chamber 160 at the other end.
  • the gas line 53 is provided with a first air filter 53 for filtering The outside air entering the gas line 53 through the duct opening 52.
  • the first air filter 53 causes the air entering the second chamber 160 to become sterile air.
  • a seal ring 54 is provided at the junction of the first purification device 51 and the first connection portion 118.
  • the cross-sectional area of the end of the gas line 53 communicating with the solvent body 11 is smaller than the cross-sectional area of the rubber plug 21, which has the advantage of preventing the rubber stopper 21 from coming out of the solvent body 11 and entering the gas line 53.
  • the second cleaning device 51 is fixedly mounted with a second magnet, and the second magnet is an electromagnet 55 for driving the permanent magnet 2101 to move, thereby driving the rubber stopper 21 to move.
  • the electromagnet 55 is not energized, the position of the permanent magnet 2101 remains unchanged.
  • the electromagnet 55 is energized in the forward direction, a repulsive force is generated between the electromagnet 55 and the permanent magnet 2101.
  • the electromagnet 55 is reversely energized, the electromagnet 55 and An attractive force is generated between the permanent magnets 2101.
  • the aseptic dispensing system provided in this embodiment further includes a third clean laminar flow device 10, the third clean laminar flow device 10 is set on the first purifying device 51, and the third clean laminar flow device 10 is provided with an annular air outlet.
  • the third clean laminar flow device 10 is in communication with the second purifying device 56 through the air tube 58 , the second air filter 57 is built in the second purifying device 56 , and the second air filter 57 is used to filter the gas from the third air pump 59 .
  • the third air pump 59 is in communication with the second purification device 56 via a conduit.
  • the third air pump 59 is activated, and the third air pump 59 pumps air into the second purifying device 56, and the air is filtered through the second air filter 57, and then sequentially flows through the air tube 58 and the third clean laminar flow device 10.
  • the sterile air is discharged through the annular air outlet on the third clean laminar flow device 10, and the sterile air forms a positive pressure at the annular air outlet.
  • the sterile air forming a positive pressure surrounds the solvent body 11 and the injection needle 22 to form a gas shield laminar flow, and the gas shield laminar flow can prevent the solvent body 11 and the injection needle 22 from coming into contact with the air with bacteria, thereby enhancing The safety of dispensing.
  • the solvent body 11 is hermetically connected to the first purification device 51.
  • the electromagnet 55 is energized in the forward direction, and the electromagnetic field generated by the electromagnet 55 drives the permanent magnet 2101 to move toward the injection needle 22, and the outside air passes through the pipeline.
  • the port 52 enters the gas line 53 and is filtered by the first air filter 53 to become sterile air, which in turn enters the second chamber 160.
  • the permanent magnet 2101 discharges the air in the first cavity 150 during the movement toward the injection needle 22.
  • the injection needle 22 When the air in the first cavity 150 is completely discharged, the injection needle 22 is inserted into the liquid medicament bottle, and then The electromagnet 55 is energized in the reverse direction, and the electromagnetic field generated by the electromagnet 55 is reversely energized to drive the permanent magnet 2101 to move away from the injection needle 22, thereby moving the rubber stopper 21 toward the first purification device 51 to inhale the liquid.
  • the control electromagnet 55 is energized in the forward direction, and the electromagnetic field generated by the electromagnet 55 is energized to drive the permanent magnet 2101 to move toward the injection needle 22.
  • the chemical solution in the first cavity 150 is caused to flow into the lyophilized powder drug bottle, and after the drug solution and the lyophilized powder are sufficiently mixed, the electromagnet 55 is reversely energized, and the electromagnetic field generated by the electromagnet 55 is reversely energized to drive the permanent
  • the magnet 2101 moves in a direction away from the injection needle 22, thereby moving the rubber stopper 21 toward the first purification device 51, and further extracting the mixture of the lyophilized powder and the medical solution into the first cavity 150 to complete the dispensing.
  • the third air pump 59 is always in operation so that the gas barrier laminar flow is always present to ensure that the drug injector body 11, the injection needle 22 and the medicament bottle are in a sterile environment.
  • FIG. 13 it is a schematic structural view of the main body of the drug solution of the present invention, as shown in FIG. 15, which is a schematic structural view of the drug dissolver of the aseptic dispensing system of the present embodiment.
  • the present embodiment provides an aseptic dispensing system comprising a drug dissolver body 11 having a first connecting portion 118 at one end and a second connecting portion 119 at the other end.
  • the first connecting portion 118 is connected to the first cleaning device 51 by a screw connection or a snap connection or a claw hook connection or a screw connection or a magnetic connection.
  • the second connecting portion 119 is connected to the injection needle 22 by a screw connection or a snap connection or a claw hook connection or a screw connection or a magnetic connection.
  • the rubber stopper 21 is built in the solvent body 11.
  • the rubber stopper 21 moves axially within the dissolver body 11.
  • the rubber plug 21 divides the solvent body 11 into a first cavity 150 and a second cavity 160.
  • the material used to make the rubber plug 21 is a high temperature resistant and biosafety silicone rubber.
  • the shape of the drug dissolver body 11 is a cylinder or an elliptical cylinder or a rectangular parallelepiped or a triangular prism.
  • the first purifying device 51 is in communication with the third air pump 60 through the joint 52.
  • the first purifying device 51 is further provided with a gas line 53.
  • One end of the gas line 53 communicates with the joint 52, and the other end communicates with the second chamber 160.
  • the gas tube The path 53 is provided with a first air filter 53 for filtering the gas from the third air pump 60, and the first air filter 53 causes the air from the third air pump 60 to become sterile air.
  • a seal ring 54 is provided at the junction of the first purification device 51 and the first connection portion 118.
  • the cross-sectional area of the end of the gas line 53 communicating with the solvent body 11 is smaller than the cross-sectional area of the rubber plug 21, which has the advantage of preventing the rubber stopper 21 from coming out of the solvent body 11 and entering the gas line 53.
  • the aseptic dispensing system provided in this embodiment further includes a fourth clean laminar flow device 100, the fourth clean laminar flow device 100 is set on the first purifying device 51, and the fourth clean laminar flow device 100 is provided with an annular air outlet.
  • the fourth clean laminar flow device 100 communicates with the second purifying device 56 through the air tube 17, the second air filter 57 is built in the second purifying device 56, and the second air filter 57 is used to filter the gas from the fourth air pump 59.
  • the fourth air pump 59 is in communication with the second purification device 56 through a conduit.
  • the fourth air pump 59 Before the start of dispensing, the fourth air pump 59 is activated, and the fourth air pump 59 pumps air into the second purifying device 56, and the air is filtered through the second air filter 57, and then sequentially flows through the air tube 17 and the fourth clean laminar flow device 100.
  • the sterile air is discharged through the annular air outlet on the fourth clean laminar flow device 100, and the sterile air forms a positive pressure at the annular air outlet.
  • the sterile air forming a positive pressure surrounds the solvent body 11 and the injection needle 22 to form a gas shield laminar flow, and the gas shield laminar flow can prevent the solvent body 11 and the injection needle 22 from coming into contact with the air with bacteria, thereby enhancing The safety of dispensing.
  • the solvent body 11 is hermetically connected to the first purification device 51.
  • the third air pump 60 presses air into the gas line 53. Since the gas line 53 communicates with the second chamber 160, the second chamber The gas pressure in 160 rises. When the gas pressure in the second chamber 160 is higher than the first chamber 150, the high pressure gas in the second chamber 160 pushes the piston to move toward the injection needle 22. The air in the first cavity 150 is completely discharged. When the air in the first cavity 150 is completely discharged, the injection needle 22 is inserted into the liquid medicine bottle, and then the gas in the second cavity 160 is passed through the third air pump 60.
  • the rubber stopper 21 moves toward the first cleaning device 51 to suck the liquid into the first cavity 150. Then, the liquid medicine bottle is removed, and the injection needle 22 is inserted into the lyophilized powder medicine bottle, and the third air pump 60 is controlled to press air into the gas line 53.
  • the air pressure in the second chamber 160 is higher than the first chamber At 150 o'clock, the high pressure gas in the second cavity 160 pushes the piston to move closer to the injection needle 22, so that the liquid medicine in the first cavity 150 flows into the lyophilized powder medicine bottle, and the drug solution is thoroughly mixed with the lyophilized powder.
  • the gas in the second cavity 160 is sucked out by the third air pump 60.
  • the rubber plug 21 moves toward the first cleaning device 51. Further, the mixture of the lyophilized powder and the drug solution is drawn into the first cavity 150 to complete the dispensing.
  • the air flowing into the second chamber 160 is purified as sterile air, preventing the interior of the solvent body 11 from being contaminated.
  • the dispensing process is safer.
  • the fourth air pump 59 is always in operation, so that the gas barrier laminar flow is always present to ensure that the drug solution body 11, the injection needle 22 and the medicament bottle are in a sterile environment.
  • the air source output device is a box structure, and the inside is divided into an upper box and a lower box by a heat insulating layer 70 to form two relatively sealed environments, and the heat insulating layer is insulated. Efficacy, to prevent unnecessary damage to the equipment caused by a large amount of heat generated by the operation of the air pump, power supply and other equipment.
  • a main working pump 79 is disposed inside the lower casing, and the main working pump 79 is equipped with a filtering device for removing oil and water to ensure the cleanliness and high performance working condition of the equipment.
  • a switch 71 is provided on the upper casing for generating a small current.
  • the side of the main working pump is provided with a triggering device 81, which receives stimulation from a small current and generates a large current, thereby controlling the on/off of the circuit of the gas source output device.
  • the electric device only has one button main pipe as the switch, and the push is opened, but this simple switch causes the working current flowing into the device to be large and not safe enough. As shown in FIG.
  • the trigger device is a relay, and after the switch 71 is pressed, the generated small current stimulates the relay 24 to make its line A certain voltage is applied to both ends of the ring, a certain current flows through the coil, thereby generating an electromagnetic effect, and the armature is attracted to the iron core against the action of the spring under the attraction of the electromagnetic force, thereby driving the movable contact and the static contact of the armature.
  • the switch is closed, the switch 71 is turned off, the switch of the relay is turned off, the electromagnetic attraction is also lost, and the armature returns to the original position under the reaction force of the spring, so that the movable contact and the movable contact The static contact is released and the circuit is disconnected.
  • the combination of the switch and the relay is to control the large current with a small current, so that the current through the device will have a buffer, which will not become sharply larger or smaller, which greatly ensures the safety of the device.
  • the front of the main working pump 79 is a voltage regulator 80 for outputting a stable voltage supply to the gas source output device to prevent sparks from occurring due to voltage instability, damage to the circuit, and the like.
  • the voltage regulator 80 includes a voltage regulating circuit, a control circuit and a servo motor. When the input voltage or load changes, the control circuit samples, compares, and amplifies, and then drives the servo motor to rotate, so that the position of the voltage brush of the voltage regulator is changed through automatic Adjust the turns ratio of the coil to keep the output voltage stable.
  • Below the main working pump 79 are provided four damping pads 87 for mitigating the vibration of the main working pump 79 and ensuring the overall stability of the gas source output device.
  • the main working pump 79, the relay 24, and the voltage regulator 80 are all high-power devices, a large amount of heat is generated during operation, so two fans 84 are disposed on the back of the lower casing for heat dissipation, and the air inlet of the fan 84 is at the lower portion. On the back side of the box body, the air outlet is on both sides.
  • This structural design is beneficial to the internal air circulation and has the best heat dissipation effect.
  • the air inlet of the fan 84 is provided with an inefficient filter, the filter material is 100% synthetic fiber, and the inefficient filter can filter out impurities such as larger particles and hair in the air to prevent it from entering the air source output device. , causing damage to its internal equipment and causing environmental pollution.
  • the heat insulation layer 70 is provided with an intermediate effect filter 3131.
  • the air inlet is below the heat insulation layer, and the air filtered by the inefficient filter in the lower box is extracted, and the equipment is effectively removed under a higher temperature environment. Water vapor and oil vapor, to avoid condensation of water into water vapor after cooling, affecting the overall cleanliness and normal use of equipment.
  • the medium efficiency filter 3131 utilizes the inertia and diffusion of the particles, electrostatic action and chemical filtration to filter the air, and has a stable structure and a good purification function.
  • the intake of the main working pump 79 is extracted through the intermediate effect filter 3131, and the outlet of the main working pump 79 is disposed in the upper casing. The main working pump is always in the state of starting. On the one hand, if it is started when it is used, there will be a delay. On the other hand, when the switch is started, an electric spark will be generated, the service life will be reduced, and the use cost will be increased.
  • a support structure 82 is provided between the bottom of the lower case and the heat insulating layer 70 for supporting the heat insulating layer 70.
  • the support structure is at least one post 261, the upper end of which is screwed to the heat insulating layer, and the lower end is screwed to the bottom of the lower case.
  • the column saves space and facilitates the heat dissipation of the main working pump, relay and voltage regulator, greatly improving the safety of the working of the gas source output device.
  • the pillar is preferably made of sheet metal, because it has good rigidity, is not easy to be broken and deformed, and can play a good supporting role. In addition, the pillar of sheet metal can effectively resist the vibration generated by the work of air pump, relay and other equipment. Greatly improve the overall stability of the gas source output device.
  • the position of the pillar is not limited to the four vertices of the heat insulation layer in FIG. 18, and may be other positions between the bottom of the lower tank and the heat insulation layer, for example, the middle point of each side of the bottom of the lower tank body and the like for facilitating the installation of the pillar.
  • a plurality of columns can be arranged between the bottom of the lower tank and the heat insulation layer.
  • the air in the upper tank is extracted by the main working pump 79 through the intermediate effect filter 3131, so it is relatively clean.
  • the upper tank is provided with a purifying device. Compared with the main working pump, the purifying device is used for outputting a smooth and gentle flow of clean air, and the main working pump is used for outputting a large flow of clean air, which can be used as a power source.
  • the upper casing is further provided with a second electromagnetic valve 73, a third electromagnetic valve 74, and the purifying sub-assembly comprises: a purging pump and a first electromagnetic valve, and the three electromagnetic valves are sequentially arranged on the thermal insulation layer 70.
  • the purifying pump extracts the air inside the upper tank, and the purified air is output to the air source output device through the hose.
  • the first solenoid valve is a two-way solenoid valve disposed on the gas pipeline of the purification pump for controlling the opening and closing of the air passage.
  • the second solenoid valve 73 and the third solenoid valve 74 are three-way solenoid valves disposed on the gas pipeline of the main working pump 79 for controlling the opening and closing of the air passages in different gas transmission directions, and the air passages of the second electromagnetic valve are located.
  • the direction of gas transmission is: from the inside to the outside
  • the gas direction of the airway where the third solenoid valve is located is: from the outside to the inside.
  • the lower end of the purifying device is a circuit board 78, and the air source output device is connected by Bluetooth.
  • the circuit board 78 is used to integrate the uploaded data function, and can upload information such as the number of times of use.
  • sensors can be installed at various positions of the gas source output device, and the working state of the system can be judged by the data of the sensor, which is convenient for maintenance.
  • the upper casing has a small air outlet on the casing for discharging excess gas due to the main working pump 79 Constantly transporting gas to the upper tank will cause the internal air pressure to rise, so the air outlet is used to balance the air pressure.
  • the back casing of the upper casing is provided with a hook 77, which can be used for holding the air source output device or hanging it on a wall or the like to facilitate the user's work.
  • the output port 76 of the air source output device is disposed on the side of the upper box, and the output port 76 includes a gas path output port.
  • the gas source output device can be wired or wirelessly communicated with the outside world. If wired communication, the output port further includes a circuit output. Port for circuit connection. The setting of the output port on the side does not affect the overall aesthetics, and also avoids the cleaning dead angle, which brings inconvenience to the cleaning work.
  • the working principle of the gas source output device is:
  • FIG. 21 it is a schematic diagram of gas flow in the gas source output device.
  • the main working pump 79 is always in the working state.
  • the second electromagnetic valve 73 and the third electromagnetic valve 74 are both closed, the air flows along the intermediate effect filter 31, B1, B2, the air inlet, the air outlet, A2, A1.
  • the purging pump extracts the air in the upper tank, the first solenoid valve controls the opening and closing of the air passage, the air passes through the tee, and finally outputs from the output port 76, and the output air is a smooth and gentle small flow clean air;
  • the valve When the valve is opened, the air flows along the intermediate effect filter 31, B1, B2, the air inlet, the air outlet, A2, A3, C2, C3, and finally outputs from the output port 76, and the output is a large flow of clean air, which can be used as a
  • the third electromagnetic valve 74 is opened, the air is input from the output port 76, flows along the C3, C2, B3, B2, the air inlet, the air outlet, the A2, the A1, and the air is drawn into the air source output device.
  • the main working pump 79 and the purifying sub-device as two different gas source output terminals, can provide a small flow, smooth clean air, and can provide a large flow, clean air that can be used as a power source, and the user can It is very practical for its selection. In addition, it can be replaced separately when it is renewed, it is convenient and effective to use, and it is not too expensive.
  • the present invention provides an aseptic dispensing system.
  • the output port 76 is connected with a handle 86, and the other end of the handle is detachably filled with a solvent dissolver 85.
  • the source output device delivers clean air through the handle 86.
  • a high-efficiency filter is provided in the handle to purify the air from the air source output device in order to ensure that the solvent is injected into the solvent.
  • the handle is provided with a detecting device, which is a photoelectric sensor, and a light shielding strip is arranged on the solvent dissolver, and the photoelectric sensor is used together with the light shielding tape to detect whether the solvent dissolver has been installed to the designated position.
  • a detecting device detects that the solvent dissolver is not installed on the handle, the first electromagnetic valve is opened, the purifying pump works, the front end of the handle keeps the small power clean air blowing, and the front end of the handle is replaced with a clean and sterile environment to prevent the bacteria from being dissolved. Drugs, drugs cause pollution.
  • the first solenoid valve is opened and the purge pump is stopped.
  • the dispensing operation of the aseptic dispensing system is started, and the air from the main working pump is used as the driving force for the rubber stopper movement in the dissolver.
  • the operator holds the handle and controls the operation through the relevant buttons on the handle.
  • the handle is provided with two buttons of "forward” and “reverse” for controlling the on and off of the second solenoid valve 73 and the third solenoid valve 74, respectively.
  • the "forward” button is pressed, the second solenoid valve 73 is opened, and the air flows along the intermediate effect filter 31, B1, B2, the air inlet, the air outlet, A2, A3, C2, C3, and the air is output from the air source.
  • the drug dissolver is injected through the handle and the high-efficiency filter in the handle to push the rubber plug forward, and the liquid medicine in the solvent dissolver is pushed out.
  • the front end of the rubber plug is clean and sterile air, and the back end is also Aseptic air;
  • the third solenoid valve 74 is opened, air is drawn in from the outside of the air source output device, and enters the air source output device via the handle and the high efficiency filter in the handle, and along the C3, C2 , B3, B2, air inlet, air outlet, A2, A1 flow.
  • the aseptic dispensing system through the gas source output device, as well as the high-efficiency filter to replace the air at the front end of the handle, can ensure that the cavity of the solvent dissolver always maintains a sterile environment throughout the dispensing process, greatly ensuring the patient's Medication safety.
  • the purifying sub-device is a fourth electromagnetic valve disposed on the gas pipeline of the main working pump for controlling the clean air of the small working airflow output by the main working pump.
  • the fourth solenoid valve differs from the second solenoid valve in that the fourth solenoid valve has higher precision and can control a small flow of air.
  • FIG. 23 it is a schematic diagram of the gas flow of the present embodiment.
  • the main working pump 79 is always in operation.
  • the fourth solenoid valve When the fourth solenoid valve is opened, the second solenoid valve and the third solenoid valve are closed, the air flows along the intermediate effect filter 31, B1, B2, the air inlet, the air outlet, D1, D2, and the air passes through the tee, and finally The output port 76 outputs, the output air is a smooth and gentle small flow clean air; when the second electromagnetic valve is opened, the air along the intermediate effect filter 31, B1, B2, air inlet, air outlet, A2, A3, C2 C3 flows, and finally outputs from the output port 76.
  • the output is a large flow of clean air, which can be used as a power source; when the third solenoid valve 74 is opened, air is input from the output port 76 along C3, C2, B3, and B2. The air inlet, the air outlet, the A2 and the A1 flow, and the air is pumped to the air source output device.
  • the purifying device is a gas cylinder, and the inside is filled with clean air, and the output of the small air purifying air is controlled by the switch of the gas cylinder.
  • the purifying device uses a gas cylinder with low price and convenient use.
  • the gas cylinder itself does not have the function of self-purification, so it is necessary to replace the new gas cylinder regularly to ensure that the output of the gas source output device is clean. air.
  • FIG. 24 it is a schematic diagram of gas flow in the present embodiment.
  • the gas cylinder switch When the gas cylinder switch is turned on, the clean air inside the gas cylinder is passed through the tee, and finally outputted by the output port 76, and the output air is a smooth and gentle small flow clean air; the main working pump 79 is always in working state, when the first When the two solenoid valves are opened, the air flows along the intermediate effect filters 31, B1, B2, the air inlets, the air outlets, A2, A3, C2, and C3, and finally outputs from the output port 76, and the output is a large flow of clean air.
  • the third solenoid valve 74 As a power source; when the third solenoid valve 74 is opened, air is input from the output port 76, flows along C3, C2, B3, B2, the air inlet, the air outlet, A2, A1, and the air is drawn to the air source.
  • the third solenoid valve 74 As a power source; when the third solenoid valve 74 is
  • the purifying device is a gas cylinder
  • the gas inside is from the main working pump 79
  • the gas cylinder is internally provided with a pressure control unit for detecting and balancing the gas cylinder.
  • Internal air pressure When the gas cylinder switch is opened and the gas cylinder is exhausted through the tee, the pressure control unit controls the gas cylinder to pump from the upper tank; when the gas cylinder switch is closed, the gas cylinder also stops pumping inward. Gas to maintain the air pressure balance inside the cylinder.
  • the technical solution provided by the embodiment does not need to replace the gas cylinder regularly, and is provided with a pressure control unit, which has the advantages of convenience and high efficiency.
  • FIG. 25 it is a schematic diagram of the gas flow of the present embodiment.
  • the main working pump 79 is always in the working state.
  • the air flows along the intermediate effect filter 31, B1, B2, the air inlet, the air outlet, A2, A1. , the air is discharged into the upper tank.
  • the switch of the gas cylinder is opened, the air in the bottle passes through the tee, and finally is outputted from the output port 76, and the output air is a smooth, gentle, small-flow clean air, and the gas cylinder is operated from the upper part by the pressure control unit.
  • the tank is pumped to maintain the air pressure balance inside the cylinder.
  • the air flows along the intermediate effect filter 31, B1, B2, the air inlet, the air outlet, A2, A3, C2, C3, and finally outputs from the output port 76, and the output is a large flow of clean air. It can be used as a power source; when the third solenoid valve 74 is opened, air is input from the output port 76, and flows along the C3, C2, B3, B2, the air inlet, the air outlet, the A2, and the A1, and the air is taken in.
  • the source output device is filtered, transported to the upper tank, and discharged as needed.
  • the main working pump 79 and the purifying sub-device as two different gas source output terminals, can provide a small flow, smooth clean air, and can provide a large flow, clean air that can be used as a power source, and the user can It is very practical for its selection. In addition, it can be replaced separately when it is renewed, it is convenient and effective to use, and it is not too expensive.
  • the embodiment is different from the above embodiment in that, as shown in FIG. 26, the support structure is a support plate 262, and the upper end and the lower end are provided with protrusions, and the bottom of the lower box body and the connection between the heat insulation layer and the support plate are provided.
  • the groove when connected, the protrusion is trapped in the groove.
  • the support plate is detachable structure, easy to replace, convenient and practical.
  • the support plate is provided with hollowing and reinforcing ribs. In addition to saving raw materials, the hollow design has a good heat dissipation effect.
  • the reinforcing ribs can effectively increase the strength and rigidity of the support frame, and avoid the uneven force caused by the support frame. Deformation to improve the overall stability of the device.
  • the material of the support plate is preferably sheet metal, because it has good rigidity, is not easy to be broken and deformed, and can play a good supporting role.
  • the support plate of sheet metal can effectively resist the vibration generated by the operation of air pump, relay and other equipment, and greatly improve the overall stability of the air source output device.
  • FIG. 27 is a schematic structural view of the embodiment.
  • the supporting structure between the heat insulating layer and the lower box body is: four columns are set at four vertices of the heat insulating layer, the upper end of the column is screwed with the heat insulating layer, and the lower end is screwed with the bottom of the lower box body.
  • a reinforcing rib is welded between each two adjacent columns, which serves as a reinforcement.
  • the rib is made of stainless steel material, which has the characteristics of resistance to weak corrosive medium such as steam and water. It is effective against the high temperature steam generated by the working of various equipments. The stainless steel material is not easy to be damaged, and can be used for a long time, and has high cost performance.
  • the position of the rib is not limited to the diagonal line shown in Fig. 25, and may be provided at a corner and the like where reinforcement is required.
  • the trigger device 81 used in conjunction with the switch 71 is a device for driving a triode with a single chip, and a small current from the switch is used as a base input current of the triode, and the common emitter is amplified based on the triode.
  • the technical solution provided by this embodiment has the advantages of low power consumption, high speed, and long service life.

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Abstract

An aseptic medication preparation system, comprising: a drug dissolving unit (1, 101) used for providing a cavity for mixing medicaments; and a power unit (2, 103) used for providing power to the drug dissolving unit (1, 101).

Description

一种无菌配药***Sterile dispensing system 技术领域Technical field
本发明涉及医疗器械技术领域，具体涉及一种无菌配药***。The invention relates to the technical field of medical instruments, in particular to an aseptic dispensing system.
背景技术Background technique
目前在医疗行业，临床输液配药最常用的方式还是通过手动配药，护士需要手工用注射器将安瓿瓶内的药液、粉剂等与其它药液进行混合，再将混合液注入到输液瓶或病人体内。在这一过程中，护士连续操作配药装置吸液、注液，劳动强度大，效率低，人工操作容易出错；另一方面，配药时要求护士手部不能接触配药装置的配药推杆，操作难度大，难免有失误，增加了药物被污染的风险。At present, in the medical industry, the most common way of clinical infusion dispensing is by manual dispensing. The nurse needs to manually mix the liquid medicine, powder and the like in the ampoule with other liquids, and then inject the mixture into the infusion bottle or the patient. . In this process, the nurse continuously operates the dispensing device to absorb liquid and inject liquid. The labor intensity is high, the efficiency is low, and the manual operation is easy to make mistakes. On the other hand, when the medicine is dispensed, the nurse's hand cannot contact the dispensing pusher of the dispensing device, and the operation difficulty is difficult. Big, it is inevitable that there are mistakes, increasing the risk of drug contamination.
鉴于上述缺陷，本发明创作者经过长时间的研究和实践终于获得了本发明。In view of the above drawbacks, the creators of the present invention have finally obtained the present invention after a long period of research and practice.
发明内容Summary of the invention
为解决上述技术缺陷，本发明采用的技术方案在于，提供一种无菌配药***，其包括：溶药单元，用于提供混合药剂的腔体；In order to solve the above technical deficiencies, the technical solution adopted by the present invention is to provide an aseptic dispensing system, comprising: a solvent-dissolving unit for providing a cavity for mixing the medicament;
动力单元，用于为所述溶药单元提供动力。A power unit for powering the solvent unit.
较佳的，所述无菌配药***还包括第一手持部件和除菌单元，所述手持部件与所述动力单元可拆卸地连接，所述除菌单元用于滤除空气中的杂质和细菌。Preferably, the aseptic dispensing system further comprises a first hand-held component and a sterilization unit, the hand-held component being detachably coupled to the power unit, the sterilization unit for filtering impurities and bacteria in the air .
较佳的，所述动力单元包括一管路组和第一气泵，所述第一气泵与所述管路组连通，所述管路组至少包括四个管路，所述管路组包括电磁阀组，所述电磁阀组至少包括四个电磁阀，所述电磁阀组中电磁阀的数量与所述管路组中管路数量相对应。Preferably, the power unit includes a pipeline group and a first air pump, the first air pump is in communication with the pipeline group, the pipeline group includes at least four pipelines, and the pipeline group includes electromagnetic The valve block, the solenoid valve group includes at least four solenoid valves, and the number of solenoid valves in the solenoid valve group corresponds to the number of pipelines in the pipeline group.
较佳的，所述无菌配药***还包括无菌单元，其用于构筑一无菌环境，所述无菌单元包括一配药推杆和一套杆，所述配药推杆位于所述套杆内，且所述配药推杆与所述套杆可相对运动，所述溶药单元与所述无菌单元为密封连接；所述动力单元为一致动部，其用于带动所述配药推杆前进或后退。Preferably, the aseptic dispensing system further comprises a sterile unit for constructing a sterile environment, the sterile unit comprising a dispensing push rod and a set of rods, the dispensing push rod being located in the set rod Internally, and the dispensing push rod and the sleeve rod are relatively movable, the solvent-dissolving unit is in sealing connection with the aseptic unit; the power unit is an actuating portion for driving the dispensing push rod Move forward or backward.
较佳的，所述无菌配药***还包括第一洁净层流装置、净化装置和第二气泵，所述净化装置一端与所述第一洁净层流装置连通，另一端与所述第二气泵连通。Preferably, the aseptic dispensing system further includes a first clean laminar flow device, a purifying device, and a second air pump, the purifying device having one end in communication with the first clean laminar flow device and the other end and the second air pump Connected.
较佳的，所述无菌配药***还包括第二手持部件、除菌装置、第二洁净层流装置、第一磁体和第二磁体；活塞内置于所述溶药单元，所述胶塞内设有第一磁体；所述第二手持部件一端与所述溶药单元可拆卸地连接，另一端与所述动力单元连通，所述第二手持部件内部设有第二磁体；所述第二洁净层流装置与所述动力单元连通，所述除菌装置与所述动力单元连通。Preferably, the aseptic dispensing system further comprises a second hand-held component, a sterilization device, a second clean laminar flow device, a first magnet and a second magnet; a piston is built in the solvent-dissolving unit, the rubber plug a first magnet is disposed therein; one end of the second hand-held component is detachably connected to the solvent-dissolving unit, the other end is in communication with the power unit, and the second hand-held component is internally provided with a second magnet; The second clean laminar flow device is in communication with the power unit, and the sterilization device is in communication with the power unit.
较佳的，所述除菌装置包括第一除菌装置和第二除菌装置，所述第一除菌装置设置在所述第二手持部件内部，所述第二洁净层流装置通过所述第二除菌装置与所述气动单元连通，所述第二磁体为电磁铁。Preferably, the sterilization device comprises a first sterilization device and a second sterilization device, the first sterilization device is disposed inside the second hand-held component, and the second clean laminar flow device passes through the The second sterilization device is in communication with the pneumatic unit, and the second magnet is an electromagnet.
较佳的，所述无菌配药***还包括第一净化装置、第二净化装置和第三洁净层流装置，所述第一净化装置一端与所述溶药单元连接；所述第二净化装置一端与所述第三洁净层流装置连通，另一端与所述动力单元连通，活塞内置于所述溶药器本体，所述活塞内部设有第三磁体，所述第一净化装置内部设有第四磁体。Preferably, the aseptic dispensing system further includes a first purifying device, a second purifying device, and a third clean laminar flow device, the first purifying device having one end connected to the solvent-dissolving unit; and the second purifying device One end is in communication with the third clean laminar flow device, the other end is in communication with the power unit, a piston is built in the solvent body, a third magnet is disposed inside the piston, and the first purification device is internally provided The fourth magnet.
较佳的，所述无菌配药***还包括第一净化装置、第二净化装置和第四洁净层流装置，所述动力单元包括第三气泵和第四气泵，所述第一净化装置一端与所述溶药单元连接，另一端与所述第三气泵连通；所述第二净化装置一端与所述第四洁净层流装置连通，另一端与所述第四气泵连通，活塞内置于所述溶药器本体。Preferably, the aseptic dispensing system further comprises a first purifying device, a second purifying device and a fourth clean laminar flow device, the power unit comprising a third air pump and a fourth air pump, the first purifying device having one end The drug dissolution unit is connected, and the other end is in communication with the third air pump; the second purification device has one end communicating with the fourth clean laminar flow device, and the other end is in communication with the fourth air pump, and the piston is built in the The drug dissolver body.
较佳的，所述动力单元为一种气源输出装置，其包括：Preferably, the power unit is a gas source output device, comprising:
主工作泵，其用来输出大流量洁净空气；Main working pump for outputting large flow of clean air;
净化子装置，其用来输出缓和的小流量洁净空气。A purifying device for outputting a gentle, small flow of clean air.
与现有技术比较本发明的有益效果在于：本发明提供一种无菌配药***中，所述动力单元能够为溶药单元提供动力，便于使用者进行操作，提高了溶药的效率；所述 溶药单元与所述第一手持部件采用可拆卸的连接方式连接，易于拆卸，使用方便；所述溶药单元，制造成本低，适宜批量生产和推广使用。The present invention provides an aseptic dispensing system in which the power unit is capable of powering a drug dissolution unit, facilitating operation by a user, and improving the efficiency of dissolution of the drug; The solvent-dissolving unit and the first hand-held component are connected by a detachable connection, which is easy to disassemble and convenient to use; the solvent-dissolving unit has low manufacturing cost and is suitable for mass production and popularization.
附图说明DRAWINGS
为了更清楚地说明本发明各实施例中的技术方案，下面将对实施例描述中所需要使用的附图作简单地介绍。In order to more clearly illustrate the technical solutions in the various embodiments of the present invention, the drawings used in the description of the embodiments will be briefly described below.
图1是本发明实施例一中无菌配药***结构示意图；1 is a schematic structural view of an aseptic dispensing system according to a first embodiment of the present invention;
图2是本发明实施例二中无菌配药***结构示意图；2 is a schematic structural view of an aseptic dispensing system according to a second embodiment of the present invention;
图3是本发明实施例二中第一手持部件和溶药单元的剖面图；Figure 3 is a cross-sectional view showing the first hand-held component and the drug-dissolving unit in the second embodiment of the present invention;
图4是本发明实施例二中控制单元连接示意图；4 is a schematic diagram of connection of a control unit in Embodiment 2 of the present invention;
图5是本发明实施例三中第一手持部件和溶药单元的剖面图；Figure 5 is a cross-sectional view showing the first hand-held component and the drug dissolution unit in the third embodiment of the present invention;
图6是本实施例无菌配药***的示意图一；Figure 6 is a schematic view 1 of the aseptic dispensing system of the present embodiment;
图7是本实施例无菌配药***的示意图二；Figure 7 is a schematic view 2 of the aseptic dispensing system of the present embodiment;
图8是本实施例无菌配药***的示意图三；Figure 8 is a schematic view 3 of the aseptic dispensing system of the present embodiment;
图9是本实施例无菌配药***的示意图四；Figure 9 is a schematic view 4 of the aseptic dispensing system of the present embodiment;
图10是本实施例中无菌配药***的结构示意图；Figure 10 is a schematic view showing the structure of the aseptic dispensing system in the present embodiment;
图11是本实施例中第二手持部件内部结构示意图；Figure 11 is a schematic view showing the internal structure of the second hand-held component in the embodiment;
图12是本实施例中控制单元功能示意图；Figure 12 is a schematic diagram showing the function of the control unit in the embodiment;
图13是本发明的溶药器本体的结构示意图；Figure 13 is a schematic view showing the structure of the drug dissolver body of the present invention;
图14是本实施例的无菌配药***的溶药器的结构示意图；Figure 14 is a schematic view showing the structure of a solvent dissolver of the aseptic dispensing system of the present embodiment;
图15是本实施例的无菌配药***的溶药器的结构示意图；Figure 15 is a schematic view showing the structure of a solvent dissolver of the aseptic dispensing system of the present embodiment;
图16是气源输出装置的正视图；Figure 16 is a front elevational view of the gas source output device;
图17是气源输出装置的后视图；Figure 17 is a rear elevational view of the gas source output device;
图18是气源输出装置正面内部结构示意图；Figure 18 is a schematic view showing the internal structure of the front side of the gas source output device;
图19是气源输出装置背面内部结构示意图；Figure 19 is a schematic view showing the internal structure of the back side of the air source output device;
图20是气源输出装置风扇示意图；Figure 20 is a schematic diagram of a fan of a gas source output device;
图21是本发明气体流通示意图；Figure 21 is a schematic view of the gas flow of the present invention;
图22是实施例十五的整体外观图；Figure 22 is an overall appearance view of the fifteenth embodiment;
图23是实施例十六中的气体流通示意图；Figure 23 is a schematic view showing the flow of gas in the sixteenth embodiment;
图24是实施例十七中的气体流通示意图；Figure 24 is a schematic view showing the flow of gas in the seventeenth embodiment;
图25是实施例十八的气体流通示意图；Figure 25 is a schematic view showing the flow of gas in the eighteenth embodiment;
图26是实施例十九的结构示意图；Figure 26 is a schematic structural view of Embodiment 19;
图27是实施例二十的结构示意图。Figure 27 is a schematic view showing the structure of Embodiment 20.
具体实施方式detailed description
以下结合附图，对本发明上述的和另外的技术特征和优点作更详细的说明。The above and other technical features and advantages of the present invention are described in more detail below with reference to the accompanying drawings.
本发明提供了一种无菌配药***，其包括：溶药单元，用于提供混合药剂的腔体；动力单元，用于为所述溶药单元提供动力。The present invention provides an aseptic dispensing system comprising: a drug dissolution unit for providing a cavity for mixing a medicament; and a power unit for powering the drug dissolution unit.
所述溶药单元，制造成本低，适宜批量生产和推广使用；所述动力单元能够为溶药单元提供动力，便于使用者进行操作，提高了溶药的效率。The solvent-dissolving unit has low manufacturing cost and is suitable for mass production and popularization; the power unit can provide power for the drug-dissolving unit, is convenient for the user to operate, and improves the efficiency of the drug-dissolving.
实施例一Embodiment 1
本发明提供了一种无菌配药***，其包括：溶药单元，用于提供混合药剂的腔体；动力单元，用于为所述溶药单元提供动力；第一手持部件，用于连接所述溶药单元和所述动力单元；除菌单元，用于滤除空气中的杂质和细菌。The present invention provides an aseptic dispensing system comprising: a drug dissolution unit for providing a cavity for mixing a medicament; a power unit for powering the drug dissolution unit; and a first hand held component for connecting to the a solvent unit and the power unit; a sterilization unit for filtering impurities and bacteria in the air.
如图1所示，为本实施例一中无菌配药***结构示意图。所述溶药单元1通过第一快接口2与第一手持部件3连接，动力单元4通过第二快接口5与所述第一手持部件3连接。所述除菌单元6内置于所述第一手持部件3中。FIG. 1 is a schematic structural view of the aseptic dispensing system of the first embodiment. The drug dissolution unit 1 is connected to the first hand-held component 3 via a first quick interface 2, and the power unit 4 is connected to the first hand-held component 3 via a second quick interface 5. The sterilization unit 6 is built in the first hand held part 3.
所述溶药单元包括溶药器本体11、注射针12、针托13和第一活塞14，溶药器本体11一端通过针托13与注射针12连接，溶药器本体11另一端设有用于连接第一快接口2的第一对接口15，第一活塞14内置于溶药器本体11。 The solvent-dissolving unit comprises a drug dissolver body 11, an injection needle 12, a needle holder 13 and a first piston 14. One end of the drug dissolver body 11 is connected to the injection needle 12 through a needle holder 13, and the other end of the drug dissolver body 11 is provided. The first piston 14 is built in the solvent body 11 at the first pair of interfaces 15 that connect the first quick interface 2.
针托13为一中空的相对于溶药器本体向外凸起的柱状物，用于支撑所述注射针12，所述注射针12由固定单元固定在所述针托13内，所述固定单元可为橡胶软体、树脂软体等具有密闭作用的弹性体。The needle holder 13 is a hollow column that is outwardly convex relative to the body of the dissolver for supporting the injection needle 12, and the injection needle 12 is fixed in the needle holder 13 by a fixing unit, the fixing The unit may be an elastomer having a sealing function such as a rubber soft body or a resin soft body.
溶药器本体11内表面呈圆柱状，第一活塞14为圆柱状橡胶软体，第一活塞14的外径与溶药器本体11内径相同。第一活塞14在所述溶药器本体11内轴向运动。所述第一活塞14将所述溶药器本体11内部分隔为溶药腔16和溶药器气腔17，所述溶药腔16和溶药器气腔17完全密闭隔离。The inner surface of the drug dissolver body 11 has a cylindrical shape, and the first piston 14 is a cylindrical rubber soft body, and the outer diameter of the first piston 14 is the same as the inner diameter of the solvent body 11. The first piston 14 moves axially within the solvent body 11. The first piston 14 separates the interior of the solvent body 11 into a solvent chamber 16 and a solvent chamber, and the solvent chamber 16 and the solvent chamber 17 are completely hermetically sealed.
第一手持部件3包括壳体31和第二活塞32，壳体31一端设有第一快接口2，所述壳体31另一端设有第二快接口5。所述第二活塞32内置于壳体31。制作所述第二活塞32所使用的材料为耐高温且具有生物安全性的硅橡胶。The first hand-held component 3 includes a housing 31 and a second piston 32. One end of the housing 31 is provided with a first quick interface 2, and the other end of the housing 31 is provided with a second quick interface 5. The second piston 32 is built in the housing 31. The material used to make the second piston 32 is a high temperature resistant and biosafety silicone rubber.
壳体31内表面呈圆柱状，第二活塞32为圆柱状橡胶软体，第二活塞32的外径与所述壳体31内径相同。所述第二活塞32在所述壳体31内轴向运动。The inner surface of the casing 31 has a cylindrical shape, the second piston 32 is a cylindrical rubber soft body, and the outer diameter of the second piston 32 is the same as the inner diameter of the casing 31. The second piston 32 moves axially within the housing 31.
所述除菌单元6包括除菌装置61，除菌装置61安装在所述壳体31内部。The sterilization unit 6 includes a sterilization device 61, and the sterilization device 61 is installed inside the casing 31.
所述除菌装置61至少包括聚丙烯，硅藻土，玻璃纤维，混合纤维素酯，聚偏二氟乙烯，聚四氟乙烯，聚醚矾，尼龙，纤维素酯，改良纤维素当中的一种，所述除菌装置61的过滤孔径不超过0.22微米。The sterilization device 61 comprises at least one of polypropylene, diatomaceous earth, glass fiber, mixed cellulose ester, polyvinylidene fluoride, polytetrafluoroethylene, polyether oxime, nylon, cellulose ester, and modified cellulose. The filtration pore size of the sterilization device 61 does not exceed 0.22 micrometers.
所述除菌装置61和所述第二活塞32共同将所述壳体31分隔为第一气腔33、第二气腔34、第三气腔35，所述第一气腔33位于所述第二活塞32与第二快接口5之间，所述第二气腔34位于所述第二活塞32与所述除菌装置61之间，所述第三气腔35位于所述除菌装置61与第一快接口2之间。所述第一气腔33和第二气腔34完全密闭隔离，所述第二气腔34和第三气腔35通过所述除菌装置61相互连通。所述溶药器气腔17、所述第二气腔34和第三气腔35内的气压相同。The sterilization device 61 and the second piston 32 collectively divide the housing 31 into a first air chamber 33, a second air chamber 34, and a third air chamber 35, and the first air chamber 33 is located at the Between the second piston 32 and the second quick interface 5, the second air chamber 34 is located between the second piston 32 and the sterilization device 61, and the third air chamber 35 is located at the sterilization device 61 is between the first fast interface 2. The first air chamber 33 and the second air chamber 34 are completely hermetically sealed, and the second air chamber 34 and the third air chamber 35 are in communication with each other through the sterilization device 61. The gas pressures in the solvent chamber, the second chamber 34, and the third chamber 35 are the same.
所述动力单元4包括第一气泵41和气泵开关42，所述第一气泵41上设有用于连接第二快接口5的第二对接口43。所述第一气泵41通过所述第二快接口5与第一气腔33连通。所述气泵开关42上设有待机档位、充气档位和排气档位。所述第一气泵41工作提供两种工作模式，其工作模式包括增压过程和减压过程。The power unit 4 includes a first air pump 41 and a gas pump switch 42, and the first air pump 41 is provided with a second pair of interfaces 43 for connecting the second quick interface 5. The first air pump 41 is in communication with the first air chamber 33 through the second quick interface 5 . The air pump switch 42 is provided with a standby gear position, an inflation gear position and an exhaust gear position. The operation of the first air pump 41 provides two modes of operation, the mode of operation including a pressurization process and a depressurization process.
所述增压过程为：The pressurization process is:
所述气泵开关42调整至充气档位，所述第一气泵41向第一气腔33泵入空气，增加第一气腔33内的气压，当第一气腔33内的气压高于第二气腔34时，第一气腔33内的高压气体推动第二活塞32向远离第一气泵41方向运动，第二气腔34内的气体通过所述除菌装置61逐步流入第三气腔35，因此第三气腔35内的空气为过滤后的无菌空气。由于第三气腔35通过第一快接口2与溶药器气腔17连通，所以第三气腔35内的气体逐步流入溶药器气腔17，当溶药器气腔17内的气压高于溶药腔16内的压力时，溶药器气腔17内的高压气体会推动所述第一活塞14向靠近针托13方向运动。The air pump switch 42 is adjusted to the inflating gear position, and the first air pump 41 pumps air into the first air chamber 33 to increase the air pressure in the first air chamber 33. When the air pressure in the first air chamber 33 is higher than the second air chamber 33 When the air chamber 34 is in the air chamber 34, the high pressure gas in the first air chamber 33 pushes the second piston 32 to move away from the first air pump 41, and the gas in the second air chamber 34 gradually flows into the third air chamber 35 through the sterilization device 61. Therefore, the air in the third air chamber 35 is filtered sterile air. Since the third air chamber 35 communicates with the solvent chamber 17 through the first quick interface 2, the gas in the third air chamber 35 gradually flows into the solvent chamber 17 of the solvent, and the gas pressure in the air chamber 17 of the solvent is higher than that. The pressure in the drug chamber 16 causes the high pressure gas in the solvent chamber 17 to urge the first piston 14 toward the needle holder 13.
所述气泵减压过程为：The air pump decompression process is:
所述气泵开关42调整至排气档位，所述第一气泵41将第一气腔33内的空气泵出，第一气腔33内的气压下降，当第一气腔33内的气压低于第二气腔34时，第二气腔34内的高压气体推动第二活塞32向靠近第一气泵41方向运动，使第三气腔35内的气体逐步流入第二气腔34，继而溶药器气腔17内的气体流入第三气腔35内，当溶药器气腔17内的气压低于溶药腔16内的压力时，所述第一活塞14向远离针托13方向运动。The air pump switch 42 is adjusted to the exhaust gear position, the first air pump 41 pumps the air in the first air chamber 33, the air pressure in the first air chamber 33 is lowered, and the air pressure in the first air chamber 33 is low. In the second air chamber 34, the high pressure gas in the second air chamber 34 pushes the second piston 32 to move toward the first air pump 41, so that the gas in the third air chamber 35 gradually flows into the second air chamber 34, and then dissolves. The gas in the drug chamber 17 flows into the third air chamber 35. When the air pressure in the solvent chamber 17 is lower than the pressure in the solvent chamber 16, the first piston 14 moves away from the needle holder 13. .
无菌配药***的工作原理为：The working principle of the aseptic dispensing system is:
首先将第二对接口43与第二快接口5连接，再将第一对接口15与第一快接口相连，连接完成后，将所述气泵开关42调整至充气档位，执行第一次增压过程，将溶药腔16内的空气全部排出，当溶药腔16内的空气全部排出后，将注射针12***液体药剂瓶中，然后调整所述气泵开关42至排气档位，执行第一次减压过程，药液流入溶药腔16内，然后移除液体药剂瓶，将注射针12***冻干粉药剂瓶中，进而执行第二次增压过程，使溶药腔16内药液流入冻干粉药剂瓶中，待药液与冻干粉充分混合后，执行第二次减压过程，将冻干粉与药液的混合物抽取至溶药腔内， 完成溶药。无菌配药***工作过程中，所述溶药器气腔17内的空气始终保持为过滤后的无菌空气，防止溶药器本体11内部遭受污染，使溶药过程更加安全。Firstly, the second pair of interfaces 43 are connected to the second quick interface 5, and then the first pair of interfaces 15 are connected to the first quick interface. After the connection is completed, the air pump switch 42 is adjusted to the inflated gear position, and the first increase is performed. During the pressing process, the air in the solvent chamber 16 is completely discharged. When the air in the solvent chamber 16 is completely discharged, the injection needle 12 is inserted into the liquid medicine bottle, and then the air pump switch 42 is adjusted to the exhaust gear position, and execution is performed. During the first decompression process, the drug solution flows into the drug dissolution chamber 16, and then the liquid drug bottle is removed, and the injection needle 12 is inserted into the lyophilized powder drug bottle, thereby performing a second pressurization process to make the drug solution chamber 16 The medicine liquid flows into the lyophilized powder medicine bottle, and after the medicine liquid and the lyophilized powder are thoroughly mixed, the second decompression process is performed, and the mixture of the lyophilized powder and the medicine liquid is extracted into the solvent cavity. Complete the dissolution. During the operation of the aseptic dispensing system, the air in the solvent chamber 17 is always kept as sterile air after filtration, preventing the interior of the solvent body 11 from being contaminated, and making the solvent-dissolving process safer.
实施例二 Embodiment 2
本实施例提供了一种无菌配药***，其包括：溶药单元，用于提供混合药剂的腔体；动力单元，用于为所述溶药单元提供动力；第一手持部件，用于连接所述溶药单元和所述动力单元；除菌单元，用于滤除空气中的杂质和细菌；控制单元，用于控制所述动力单元。The present embodiment provides an aseptic dispensing system comprising: a drug dissolution unit for providing a cavity for mixing a medicament; a power unit for powering the drug dissolution unit; and a first hand-held component for connecting The solvent unit and the power unit; a sterilization unit for filtering impurities and bacteria in the air; and a control unit for controlling the power unit.
如图2所示，为本实施例二中无菌配药***结构示意图。所述溶药单元101与所述第一手持部件102通过螺纹连接，所述除菌单元与所述动力单元103连接，所述动力单元103与所述第一手持部件102通过气管104连接，所述控制单元105分别与所述第一手持部件102和所述动力单元103通过导线连接，所述控制单元105用于控制所述动力单元103。FIG. 2 is a schematic view showing the structure of the aseptic dispensing system in the second embodiment. The solvent-dissolving unit 101 is screwed to the first hand-held component 102, the sterilization unit is connected to the power unit 103, and the power unit 103 is connected to the first hand-held component 102 through a gas pipe 104. The control unit 105 is connected to the first hand-held component 102 and the power unit 103 by wires, and the control unit 105 is used to control the power unit 103.
所述溶药单元101包括溶药器本体111、注射针112、针托113和第一活塞114，所述溶药器本体111的前端通过所述针托113与所述注射针112连接，所述溶药器本体111的尾端与所述第一手持部件102通过螺纹连接，所述第一活塞114内置于所述溶药器本体111。The drug dissolution unit 101 includes a drug dissolver body 111, an injection needle 112, a needle holder 113, and a first piston 114. The front end of the drug solution body 111 is connected to the injection needle 112 through the needle holder 113. The tail end of the dissolver body 111 is screwed to the first hand-held component 102, and the first piston 114 is built in the solvent body 111.
所述针托113为一中空的相对于溶药器本体向外凸起的柱状物，用于支撑所述注射针112，所述注射针112由固定单元固定在所述针托113内，所述固定单元可为橡胶软体、树脂软体等具有密闭作用的弹性体。The needle holder 113 is a hollow column that is outwardly convex relative to the drug sol body for supporting the injection needle 112. The injection needle 112 is fixed in the needle holder 113 by a fixing unit. The fixing unit may be an elastomer having a sealing function such as a rubber soft body or a resin soft body.
所述溶药器本体111内表面呈圆柱状，所述第一活塞114为圆柱状橡胶软体，所述第一活塞114的外径与所述溶药器本体111内径相同。所述第一活塞114在所述溶药器本体111内轴向运动。所述第一活塞114将所述溶药器本体111内部分隔为溶药腔116和溶药器气腔117，所述溶药腔116和溶药器气腔117完全密闭隔离。The inner surface of the solvent body 111 is cylindrical, the first piston 114 is a cylindrical rubber soft body, and the outer diameter of the first piston 114 is the same as the inner diameter of the solvent body 111. The first piston 114 moves axially within the solvent body 111. The first piston 114 separates the interior of the solvent body 111 into a solvent chamber 116 and a solvent chamber 117, and the solvent chamber 116 and the solvent chamber 117 are completely hermetically sealed.
如图3所示，为本实施例二中第一手持部件和溶药单元的剖面图。所述第一手持部件102包括手柄121、手柄座122，所述手柄121的一端与所述手柄座122通过第一螺纹123连接，所述手柄121的另一端通过气动接头124与气管104连接。所述手柄121还包括推送按键125和抽吸按键126，所述推送按键125和抽吸按键126通过所述控制单元105来控制所述动力单元103。所述手柄座122内部设有第二螺纹127，该螺纹用于将所述溶药器本体111的尾端固定在所述手柄座122上。所述手柄座122还包括一密封胶垫128，所述密封胶垫128设置所述溶药器本体111与所述手柄座122之间，其用于保障所述溶药器本体111与所述手柄座122之间连接的气密性。所述手柄121为内部中空结构。As shown in FIG. 3, it is a cross-sectional view of the first hand-held component and the drug-dissolving unit in the second embodiment. The first hand-held component 102 includes a handle 121 and a handle base 122. One end of the handle 121 is connected to the handle base 122 by a first thread 123, and the other end of the handle 121 is connected to the air tube 104 via a pneumatic joint 124. The handle 121 further includes a push button 125 and a suction button 126, and the push button 125 and the suction button 126 control the power unit 103 through the control unit 105. The handle base 122 is internally provided with a second thread 127 for fixing the tail end of the solvent body 111 to the handle seat 122. The handle base 122 further includes a sealing pad 128, and the sealing pad 128 is disposed between the solvent body 111 and the handle seat 122 for securing the solvent body 111 and the The airtightness of the connection between the handle seats 122. The handle 121 is an internal hollow structure.
所述动力单元103包括连接三通130、第一管路131、第二管路132、第三管路133、第四管路134、气泵135、气泵进气三通136、气泵排气三通137。The power unit 103 includes a connection tee 130, a first pipeline 131, a second pipeline 132, a third pipeline 133, a fourth pipeline 134, an air pump 135, a gas pump intake tee 136, and a gas pump exhaust tee. 137.
第一管路131包括第一电磁阀1311、第一管路前段1312和第一管路后段1313。所述第一管路前段1312和第一管路后段1313通过所述第一电磁阀1311连接。第二管路132包括第二电磁阀1321、第二管路前段1322和第二管路后段1323。所述第二管路前段1322与第二管路后段1323通过第二电磁阀1321连接。所述第三管路133包括第三电磁阀1331、第三管路前段1332和第三管路后段1333。第三管路前段1332与第三管路后段1333通过第三电磁阀1331连接。所述第四管路134包括第四电磁阀1341、第四管路前段1342和第四管路后段1343。第四管路前段1342和第四管路后段1343通过第四电磁阀1341连接。The first line 131 includes a first solenoid valve 1311, a first line front section 1312, and a first line rear section 1313. The first pipeline front section 1312 and the first pipeline rear section 1313 are connected by the first solenoid valve 1311. The second conduit 132 includes a second solenoid valve 1321, a second conduit front section 1322, and a second conduit rear section 1323. The second pipeline front section 1322 and the second pipeline rear section 1323 are connected by a second electromagnetic valve 1321. The third conduit 133 includes a third solenoid valve 1331, a third conduit front section 1332, and a third conduit rear section 1333. The third pipeline front section 1332 and the third pipeline rear section 1333 are connected by a third solenoid valve 1331. The fourth conduit 134 includes a fourth solenoid valve 1341, a fourth conduit front section 1342, and a fourth conduit rear section 1343. The fourth pipeline front section 1342 and the fourth pipeline rear section 1343 are connected by a fourth solenoid valve 1341.
气泵135包括气泵进气口1351和气泵排气口1352。气泵进气三通136三个端口分别与气泵进气口1351、第一管路后段1313和第二管路后段1323相连接。气泵排气三通137三个端口分别与气泵排气口1352、第三管路后段1333和第四管路后段1343相连接。连接三通130的三个端口分别与气管104、第二管路前段1322和第三管路前段1332相连接。The air pump 135 includes a gas pump intake port 1351 and a gas pump exhaust port 1352. The three ports of the air pump intake tee 136 are respectively connected to the air pump inlet 1351, the first pipeline rear section 1313 and the second pipeline rear section 1323. The three ports of the air pump exhaust tee 137 are respectively connected to the air pump exhaust port 1352, the third pipeline rear section 1333 and the fourth pipeline rear section 1343. The three ports connecting the three-way 130 are connected to the air pipe 104, the second pipe front section 1322, and the third pipe front section 1332, respectively.
所述除菌单元为过滤器，所述过滤器设置在进气口141和排气口142上，即在过滤器的作用下，进气口141和排气口142同时具备进气、出气和过滤除菌的功能，所述进气口141与第一管路前段1312连接，所述排气口142与所述第四管路前段 1342连接。所述设置在进气口141和排气口142上的过滤器至少包括包括聚丙烯，硅藻土，玻璃纤维，混合纤维素酯，聚偏二氟乙烯，聚四氟乙烯，聚醚砜，尼龙，纤维素酯，改良纤维素当中的一种。进气口141和排气口142上的过滤器的过滤孔径均不超过0.22微米。所述除菌单元使进入气泵135和溶药器气腔117内部的气体均为无菌空气。The sterilization unit is a filter, and the filter is disposed on the air inlet 141 and the air outlet 142, that is, under the action of the filter, the air inlet 141 and the air outlet 142 have both intake air and air outlet. Filtering the function of sterilization, the air inlet 141 is connected to the first pipeline front section 1312, and the exhaust port 142 and the fourth pipeline front section 1342 connection. The filter disposed on the air inlet 141 and the exhaust port 142 includes at least polypropylene, diatomaceous earth, glass fiber, mixed cellulose ester, polyvinylidene fluoride, polytetrafluoroethylene, polyethersulfone, One of nylon, cellulose ester, and modified cellulose. The filter apertures of the filters on the inlet 141 and the outlet 142 are each no more than 0.22 microns. The sterilization unit causes the gas entering the air pump 135 and the interior of the solvent chamber 117 to be sterile air.
如图4所示，为本实施例二中控制单元连接示意图，控制单元105分别与所述气泵135、推送按键125、抽吸按键126、第一电磁阀1311、第二电磁阀1321、第三电磁阀1331和第四电磁阀1341连接。As shown in FIG. 4, the control unit is connected to the air pump 135, the push button 125, the suction button 126, the first solenoid valve 1311, the second solenoid valve 1321, and the third. The solenoid valve 1331 is connected to the fourth solenoid valve 1341.
所述控制单元105执行的第一控制逻辑为：在单独按动推送按键125后，第一电磁阀1311与第三电磁阀1331打开，第二电磁阀1321和第四电磁阀1341关闭，气泵135开始工作。The first control logic executed by the control unit 105 is that after the push button 125 is pressed separately, the first solenoid valve 1311 and the third solenoid valve 1331 are opened, the second solenoid valve 1321 and the fourth solenoid valve 1341 are closed, and the air pump 135 is closed. start working.
执行第一控制逻辑，使空气依次流经进气口141、第一管路前段1312、第一电磁阀1311、第一管路后段1313、气泵进气三通136、气泵进气口1351、气泵排气口1352、气泵排气三通137、第三管路后段1333、第三电磁阀1331、第三管路前段1332、连接三通130、气管104、手柄121内部和溶药器气腔117，当溶药器气腔117内压力大于所述溶药腔116时，溶药器气腔117内的高压气体推动所述第一活塞114向远离手柄121方向运动。The first control logic is executed to sequentially pass air through the air inlet 141, the first pipeline front section 1312, the first solenoid valve 1311, the first pipeline rear section 1313, the air pump intake tee 136, and the air pump inlet 1351. Air pump exhaust port 1352, air pump exhaust tee 137, third pipeline rear section 1333, third solenoid valve 1331, third pipeline front section 1332, connection tee 130, air pipe 104, handle 121 interior and solvent gas The cavity 117, when the pressure in the solvent chamber 117 is greater than the solvent chamber 116, the high pressure gas in the solvent chamber 117 pushes the first piston 114 to move away from the handle 121.
所述控制单元105执行的第二控制逻辑为：在单独按动所述抽吸按键126后，第一电磁阀1311与第三电磁阀1331关闭，第二电磁阀1321和第四电磁阀1341打开，气泵135开始工作。The second control logic executed by the control unit 105 is that after the suction button 126 is separately pressed, the first electromagnetic valve 1311 and the third electromagnetic valve 1331 are closed, and the second electromagnetic valve 1321 and the fourth electromagnetic valve 1341 are opened. The air pump 135 starts working.
执行第二控制逻辑，使所述溶药器气腔117内的气体依次流经手柄121内部、气管104、连接三通130、第二管路前段1322、第二电磁阀1321、第二管路后段1323、气泵进气三通136、气泵进气口1351、气泵排气口1352、气泵排气三通137、第四管路后段1343、第四电磁阀1341、第四管路前段1342和排气口142。当所述溶药器气腔117内的气体压力小于溶药腔116时，所述第一活塞114向靠近手柄121方向运动。The second control logic is executed to sequentially pass the gas in the solvent chamber 117 through the inside of the handle 121, the air tube 104, the connection tee 130, the second line front section 1322, the second solenoid valve 1321, and the second line. Rear section 1323, air pump intake tee 136, air pump inlet 1351, air pump exhaust port 1352, air pump exhaust tee 137, fourth pipeline rear section 1343, fourth solenoid valve 1341, fourth pipeline front section 1342 And an exhaust port 142. When the gas pressure in the solvent chamber 117 is less than the solvent chamber 116, the first piston 114 moves toward the handle 121.
本实施例二中无菌配药***工作原理：The working principle of the aseptic dispensing system in the second embodiment:
首先，将所述溶药器本体111尾端与所述手柄座122固定连接在一起，然后按动推送按键125，执行第一控制逻辑，将溶药腔116内的空气全部排出，当溶药腔116内的空气全部排出后，松开推送按键125，并将注射针112***液体药剂瓶中，然后按动抽吸按键126，执行第二控制逻辑，当药液流入溶药腔116内之后，松开按动抽吸按键126，移除液体药剂瓶，将注射针112***冻干粉药剂瓶中，进而按动推送按键125，执行第一控制逻辑，使溶药腔116内药液流入冻干粉药剂瓶中，待药液与冻干粉充分混合后，按动抽吸按键126，执行第二控制逻辑，将冻干粉与药液的混合物抽取至溶药腔内，完成溶药。无菌配药***工作过程中，所述溶药器气腔117内的空气始终保持为过滤后的无菌空气，防止溶药器本体111内部遭受污染，使溶药过程更加安全。First, the tail end of the solvent body 111 is fixedly connected with the handle base 122, and then the push button 125 is pressed to execute the first control logic to discharge all the air in the solvent chamber 116. After the air in the cavity 116 is completely discharged, the push button 125 is released, and the injection needle 112 is inserted into the liquid drug bottle, and then the suction button 126 is pressed to execute the second control logic, after the drug solution flows into the drug solution chamber 116. Release the push button 126, remove the liquid medicament bottle, insert the needle 112 into the lyophilized powder bottle, and press the push button 125 to execute the first control logic to allow the drug solution into the drug solution chamber 116 to flow into the drug solution. In the lyophilized powder medicine bottle, after the medicine liquid and the lyophilized powder are thoroughly mixed, the suction button 126 is pressed to execute the second control logic, and the mixture of the lyophilized powder and the medicine liquid is extracted into the solvent cavity to complete the dissolution medicine. . During the operation of the aseptic dispensing system, the air in the solvent chamber 117 is always kept as sterile air after filtration, preventing the interior of the solvent body 111 from being contaminated, and making the solvent-dissolving process more secure.
实施例三 Embodiment 3
本实施例提供了一种无菌配药***，其与实施例二的不同之处在于：其除菌单元内置于所述第一手持部件202中，即其进气口141和排气口142仅具有进气和出气功能，并且其手持部件102还包括第二活塞223。The present embodiment provides an aseptic dispensing system that differs from the second embodiment in that a sterilization unit is built in the first hand-held component 202, that is, the air inlet 141 and the air outlet 142 are only It has an intake and exhaust function, and its hand held component 102 also includes a second piston 223.
如图5所示，为本实施例三中第一手持部件和溶药单元的剖面图，所述第二活塞223内置于所述手柄221。制作所述第二活塞223所使用的材料为耐高温且具有生物安全性的硅橡胶。所述手柄121内表面呈圆柱状，所述第二活塞223为圆柱状橡胶软体，所述第二活塞223的外径与所述手柄121内径相同。所述第二活塞223在所述手柄121内轴向运动。所述除菌单元内置于所述手柄121中。除菌单元为过滤器206，过滤器206至少包括聚丙烯，硅藻土，玻璃纤维，混合纤维素酯，聚偏二氟乙烯，聚四氟乙烯，聚醚矾，尼龙，纤维素酯，改良纤维素当中的一种，所述过滤器206的过滤孔径不超过0.22微米。As shown in FIG. 5 , which is a cross-sectional view of the first hand-held component and the drug dissolution unit in the third embodiment, the second piston 223 is built in the handle 221 . The material used to make the second piston 223 is a high temperature resistant and biosafety silicone rubber. The inner surface of the handle 121 has a cylindrical shape, the second piston 223 is a cylindrical rubber soft body, and the outer diameter of the second piston 223 is the same as the inner diameter of the handle 121. The second piston 223 moves axially within the handle 121. The sterilization unit is built in the handle 121. The sterilization unit is a filter 206, and the filter 206 comprises at least polypropylene, diatomaceous earth, glass fiber, mixed cellulose ester, polyvinylidene fluoride, polytetrafluoroethylene, polyether oxime, nylon, cellulose ester, improved In one of the celluloses, the filter 206 has a filtration pore size of no more than 0.22 microns.
过滤器206和所述第二活塞223共同将所述手柄121分隔为第一气腔2211、第 二气腔2212、第三气腔2213，所述第一气腔2211位于所述第二活塞223和气动接头124之间，所述第二气腔2212位于所述第二活塞223与所述过滤器206之间，所述第三气腔2213位于所述过滤器206与所述手柄座122之间。所述第一气腔2211和第二气腔2212完全密闭隔离，所述第二气腔2212和第三气腔2213通过所述过滤器206相互连通。所述溶药器气腔117、所述第二气腔2212和第三气腔2213内的气压相同。The filter 206 and the second piston 223 collectively divide the handle 121 into a first air chamber 2211, a a second air chamber 2212, a third air chamber 2211, the first air chamber 2211 is located between the second piston 223 and the pneumatic joint 124, and the second air chamber 2212 is located at the second piston 223 and the filter Between the 206, the third air chamber 2213 is located between the filter 206 and the handle base 122. The first air chamber 2211 and the second air chamber 2212 are completely hermetically sealed, and the second air chamber 2212 and the third air chamber 2213 are in communication with each other through the filter 206. The gas pressures in the solvent chamber 117, the second chamber 2212, and the third chamber 2213 are the same.
执行第一控制逻辑时，使空气依次流经进气口141、第一管路前段1312、第一电磁阀1311、第一管路后段1313、气泵进气三通136、气泵进气口1351、气泵排气口1352、气泵排气三通137、第三管路后段1333、第三电磁阀1331、第三管路前段1332、连接三通130、气管104。进而，第一气腔2211内气压增加，当第一气腔2211内的气压高于第二气腔2212时，第一气腔2211内的高压气体推动第二活塞223向远离气泵135方向运动，第二活塞223的运动使第二气腔2212内的气体通过所述过滤器206逐步流入第三气腔2213，因此第三气腔2213内的空气为过滤后的无菌空气。由于第三气腔2213通过所述手柄座122与溶药器气腔117连通，所以第三气腔2213内的气体逐步流入溶药器气腔117，当溶药器气腔117内的气压高于溶药腔116内的压力时，溶药器气腔117内的高压气体会推动所述第一活塞114向靠近针托113方向运动。When the first control logic is executed, the air is sequentially flowed through the air inlet 141, the first pipeline front section 1312, the first solenoid valve 1311, the first pipeline rear section 1313, the air pump intake tee 136, and the air pump inlet 1351. The air pump exhaust port 1352, the air pump exhaust tee 137, the third pipeline rear section 1333, the third electromagnetic valve 1331, the third pipeline front section 1332, the connection tee 130, and the air pipe 104. Further, the air pressure in the first air chamber 2211 is increased. When the air pressure in the first air chamber 2211 is higher than the second air chamber 2212, the high pressure gas in the first air chamber 2211 pushes the second piston 223 to move away from the air pump 135. The movement of the second piston 223 causes the gas in the second air chamber 2212 to gradually flow into the third air chamber 2213 through the filter 206, so that the air in the third air chamber 2213 is filtered sterile air. Since the third air chamber 2213 communicates with the solvent chamber 117 through the handle seat 122, the gas in the third air chamber 2213 gradually flows into the solvent chamber 117, and the gas pressure in the solvent chamber 117 is higher than that in the solvent chamber 117. During the pressure within the drug chamber 116, the high pressure gas within the solvent chamber 117 will urge the first piston 114 toward the needle holder 113.
执行第二控制逻辑时，气泵135开始工作，使第一气腔2211内的气体依次流经气管104、连接三通130、第二管路前段1322、第二电磁阀1321、第二管路后段1323、气泵进气三通136、气泵进气口1351、气泵排气口1352、气泵排气三通137、第四管路后段1343、第四电磁阀1341、第四管路前段1342和排气口142。因此，第一气腔2211内的气压下降，当第一气腔2211内的气压低于第二气腔2212时，第二气腔2212内的气体推动第二活塞223向靠近气泵135方向运动，使第三气腔2213内的气体逐步流入第二气腔2212，继而溶药器气腔117内的气体流入第三气腔2213内，当溶药器气腔117内的气压低于溶药腔116内的压力时，所述第一活塞114向远离针托113方向运动。When the second control logic is executed, the air pump 135 starts to operate, so that the gas in the first air chamber 2211 sequentially flows through the air pipe 104, the connection tee 130, the second pipeline front section 1322, the second solenoid valve 1321, and the second pipeline. Section 1323, air pump intake tee 136, air pump inlet 1351, air pump exhaust port 1352, air pump exhaust tee 137, fourth pipeline rear section 1343, fourth solenoid valve 1341, fourth pipeline front section 1342 and Exhaust port 142. Therefore, the air pressure in the first air chamber 2211 decreases. When the air pressure in the first air chamber 2211 is lower than the second air chamber 2212, the gas in the second air chamber 2212 pushes the second piston 223 toward the air pump 135. The gas in the third air chamber 2213 is gradually flowed into the second air chamber 2212, and then the gas in the solvent chamber 117 flows into the third air chamber 2213. When the gas pressure in the solvent chamber 117 is lower than the solvent chamber When the pressure within 116 is reached, the first piston 114 moves away from the needle holder 113.
实施例四Embodiment 4
本实施例提供了一种无菌配药***，其包括：This embodiment provides an aseptic dispensing system comprising:
一溶药单元；a drug dissolution unit;
一无菌单元，其用于构筑一无菌环境，所述无菌单元包括一配药推杆和一套杆，所述配药推杆位于所述套杆内；a sterile unit for constructing a sterile environment, the sterile unit comprising a dispensing push rod and a set of rods, the dispensing push rod being located in the set rod;
一致动部，其用于带动所述配药推杆前进或后退；所述配药推杆与所述致动部为可拆卸式连接；An actuating portion for driving the dispensing pusher to advance or retreat; the dispensing pusher and the actuating portion are detachably connected;
所述溶药单元与所述无菌单元为密封连接。The solvent unit is in a sealed connection with the sterile unit.
所述无菌配药***还包括第一洁净层流装置、净化装置和第二气泵。The aseptic dispensing system also includes a first clean laminar flow device, a purification device, and a second air pump.
所述无菌单元包括一配药推杆和一套杆，所述配药推杆位于所述套杆内；所述无菌单元可以为一次性部件，为避免细菌进入所述溶药单元，将与所述溶药单元连接的所述配药推杆外设置一套杆，从而使所述配药推杆处于无菌环境；所述配药推杆在所述套杆内部由固定件固定，所述固定件的固定形式可以为两端固定或螺旋固定。其中，配药推杆即为前段推杆410。The sterile unit includes a dispensing push rod and a set of rods, the dispensing push rod is located in the set rod; the sterile unit may be a disposable component, and in order to prevent bacteria from entering the solvent-dissolving unit, a set of rods is disposed outside the dispensing pusher connected to the solvent-dissolving unit, so that the dispensing push rod is in a sterile environment; the dispensing push rod is fixed inside the sleeve by a fixing member, the fixing member The fixed form can be fixed at both ends or screwed. Among them, the dispensing pusher is the front pusher 410.
所述溶药单元包括一溶药器本体11和一胶塞21，所述溶药单元具有空腔，所述空腔由所述溶药器本体11与所述胶塞21之间的空隙形成，所述空腔大小可随所述溶药器本体11与所述胶塞21的相对位置变化而变化。The drug dissolution unit includes a drug dissolver body 11 and a rubber stopper 21 having a cavity formed by a gap between the drug dissolver body 11 and the rubber stopper 21 The size of the cavity may vary depending on the relative position of the dissolver body 11 and the rubber stopper 21.
所述动力单元为一致动部，所述致动部包括：一推杆电机310、一推杆齿轮311、一旋转支撑环312和一外螺纹推杆313。The power unit is an actuating portion, and the actuating portion comprises: a push rod motor 310, a push rod gear 311, a rotating support ring 312 and an external thread push rod 313.
推杆电机310用于为所述致动部提供动力，作为动力机构的推杆电机310可为步进式直线电机、永磁式直线电机和其他任意形式的直线电机；所述推杆齿轮311与所述推杆电机310相连接，所述推杆齿轮311用于将所述推杆电机310提供的动力传递给后续单元；所述旋转支撑环312外部具有齿形结构，所述旋转支撑环312外部的齿形结构与所述推杆齿轮311的齿相啮合，所述旋转支撑环312内部设有内 螺纹，所述旋转支撑环312被外部结构固定，使得所述旋转支撑环312仅能够在所述推杆齿轮311的带动下绕轴转动，不能够进行各个方向的平动，所述外螺纹推杆313置于所述旋转支撑环312内部，且所述外螺纹推杆313的外螺纹与所述旋转支撑环312的内螺纹相配合。The push rod motor 310 is used to power the actuating portion, and the push rod motor 310 as a power mechanism may be a step linear motor, a permanent magnet linear motor, and any other type of linear motor; the push rod gear 311 Connected to the push rod motor 310, the push rod gear 311 is used to transmit the power provided by the push rod motor 310 to a subsequent unit; the rotating support ring 312 has a toothed structure on the outside, the rotating support ring The outer toothed structure of the 312 meshes with the teeth of the push rod gear 311, and the inner side of the rotating support ring 312 is internally provided Threaded, the rotating support ring 312 is fixed by the outer structure, so that the rotating support ring 312 can only pivot under the driving of the push rod gear 311, and can not perform translation in all directions, the external thread pushing A rod 313 is placed inside the rotating support ring 312, and an external thread of the externally threaded push rod 313 cooperates with an internal thread of the rotating support ring 312.
推杆电机310旋转，带动与之相连接的推杆齿轮311旋转，推杆齿轮311旋转带动进一步带动与之相啮合的旋转支撑环312旋转，由于旋转支撑环312仅能够在所述推杆齿轮311的带动下绕轴转动，不能够进行各个方向的平动，旋转支撑环312的旋转将会带动所述外螺纹推杆313沿轴线方向平动。The push rod motor 310 rotates to drive the push rod gear 311 connected thereto to rotate, and the push rod gear 311 rotates to further rotate the rotating support ring 312 engaged with the rotating support ring 312 only in the push rod gear. The rotation of the shaft 311 is not able to perform translation in all directions, and the rotation of the rotation support ring 312 will drive the external thread push rod 313 to move in the axial direction.
所述结合部包括：一齿轮组、一杆头旋转电机413、一平行导轨414和一支撑环415；The joint portion includes: a gear set, a head rotating electric machine 413, a parallel rail 414 and a support ring 415;
所述齿轮组包括一第一齿轮411、一第二齿轮412；The gear set includes a first gear 411 and a second gear 412;
所述的结合部由外螺纹推杆313带动，外螺纹推杆313端部与第一齿轮411一侧相连接，第一齿轮411随所述外螺纹推杆313沿轴线方向做平动运动，且第一齿轮411与外螺纹推杆313为活动连接，即，所述第一齿轮411可相对外螺纹推杆313转动；第一齿轮411另一侧与前段推杆410一端相连接，第一齿轮411带动前段推杆410平动及同轴转动，前段推杆410另一端设置有内螺纹，胶塞21尾端设置有与前段推杆410上的内螺纹相对应的外螺纹接头210；所述前段推杆410外部设置有所述支撑环4。The joint portion is driven by the external thread push rod 313, and the end portion of the external thread push rod 313 is connected to one side of the first gear 411, and the first gear 411 is moved in the axial direction along with the external thread push rod 313. The first gear 411 is movably connected with the externally-threaded push rod 313, that is, the first gear 411 is rotatable relative to the externally-threaded push rod 313; the other side of the first gear 411 is connected to one end of the front-stage push rod 410, first The gear 411 drives the front push rod 410 to rotate and rotate coaxially. The other end of the front push rod 410 is provided with an internal thread, and the rubber plug 21 is provided with an externally threaded joint 210 corresponding to the internal thread on the front push rod 410. The support ring 4 is disposed outside the front stage push rod 410.
所述杆头旋转电机413用于对所述前段推杆410提供旋转扭力从而使所述前段推杆410与所述胶塞21上的所述外螺纹接头210相旋合，所述杆头旋转电机413与所述第二齿轮412相连接，所述第二齿轮412与所述第一齿轮411相啮合；所述杆头旋转电机413可沿所述平行导轨414滑动，当所述前段推杆410沿轴线方向平动时，所述杆头旋转电机413沿所述平行导轨414同步滑动。The head rotating electric machine 413 is configured to provide a rotating torque to the front stage push rod 410 to screw the front stage push rod 410 with the externally threaded joint 210 on the rubber plug 21, the head rotation The motor 413 is coupled to the second gear 412, the second gear 412 is meshed with the first gear 411; the head rotating motor 413 is slidable along the parallel rail 414 when the front section push rod When the shaft 410 is translated in the axial direction, the head rotating electric machine 413 slides synchronously along the parallel rails 414.
当所述外螺纹推杆313在所述旋转支撑环312的带动下沿轴线方向平动时，所述外螺纹推杆313带动所述前段推杆410运动，同时，所述致动部带动所述杆头旋转电机413沿所述平行导轨414与所述前段推杆410同步滑动；初始状态时，所述前段推杆410处于所述溶药器本体11的远端位置，此时，所述前段推杆410未伸入所述溶药器本体11内部，所述胶塞21位于所述溶药器本体11的最前端，在所述外螺纹推杆313的带动下，所述前段推杆410逐渐伸入所述溶药器本体11内部，当所述前段推杆410与所述胶塞21上的所述外螺纹接头210相接触时，所述杆头旋转电机413启动，进而带动所述第二齿轮412转动，所述第二齿轮412转动带动与之相啮合的所述第一齿轮411转动，所述第一齿轮411带动所述前段推杆410转动，所述前段推杆410一边前进一边绕轴旋转，从而将所述前段推杆410的内螺纹与所述外螺纹接头210相旋合，此时所述前段推杆410与所述胶塞21相结合。When the externally-threaded push rod 313 is moved in the axial direction by the rotation support ring 312, the externally-threaded push rod 313 drives the front-stage push rod 410 to move, and at the same time, the actuating portion drives the The head rotating electric machine 413 slides synchronously with the front stage push rod 410 along the parallel rail 414; in the initial state, the front stage push rod 410 is at the distal end position of the solvent body 11 at this time, The front push rod 410 does not protrude into the interior of the solvent body 11. The rubber plug 21 is located at the foremost end of the solvent body 11, and the front push rod is driven by the external thread push rod 313. 410 gradually extends into the interior of the solvent body 11. When the front push rod 410 is in contact with the external threaded joint 210 on the rubber plug 21, the head rotating motor 413 is activated, thereby driving the The second gear 412 rotates, the second gear 412 rotates to drive the first gear 411 meshing with the first gear 411, the first gear 411 drives the front push rod 410 to rotate, and the front push rod 410 rotates Rotating around the axis to advance the internal thread of the front push rod 410 Male connector 210 screwed, said front case pusher 41 021 combined with the plug.
继而，将推杆电机310反向转动，从而使推杆电机310带动推杆齿轮311反向转动，与推杆齿轮311相啮合的旋转支撑环312反向转动，进而使外螺纹推杆313在旋转支撑环312的内螺纹带动下，沿相反方向平动，外螺纹推杆313带动第一齿轮411沿反向平动，所述第一齿轮411带动前段推杆410朝着远离溶药器本体11的方向运动，前段推杆410带动与之相结合的胶塞21朝着远离溶药器本体11的方向运动，进而通过溶药器本体11前部设置的针头完成抽吸过程；溶药器本体11可连接一针头。Then, the push rod motor 310 is reversely rotated, so that the push rod motor 310 drives the push rod gear 311 to rotate in the reverse direction, and the rotating support ring 312 that meshes with the push rod gear 311 rotates in the reverse direction, thereby causing the externally threaded push rod 313 to The internal thread of the rotating support ring 312 is driven in the opposite direction, and the externally-threaded push rod 313 drives the first gear 411 to move in the opposite direction. The first gear 411 drives the front-stage push rod 410 toward the far-dissolving body 11 . The direction movement, the front push rod 410 drives the rubber plug 21 combined with it to move away from the solvent body 11 , and then completes the suction process through the needle disposed at the front of the dissolver body 11; the solvent body 11 can be connected to a needle.
第一洁净层流装置514设置在推杆34靠近第一齿轮411一侧之上。第一洁净层流装置514上设置环形出风口，第一洁净层流装置514通过气管515与净化装置516连通，净化装置516内设有空气过滤器517，空气过滤器517用于过滤来自第二气泵518的气体，第二气泵518通过管道与净化装置516连通。The first clean laminar flow device 514 is disposed above the side of the push rod 34 that is adjacent to the first gear 411. An annular air outlet is disposed on the first clean laminar flow device 514, and the first clean laminar flow device 514 is in communication with the purifying device 516 through the air tube 515. The purifying device 516 is provided with an air filter 517, and the air filter 517 is used for filtering from the second The gas of the air pump 518, the second air pump 518 is in communication with the purification device 516 via a conduit.
在配药开始前和配药过程中，第二气泵518向净化装置516泵入空气，空气经净化装置516内的空气过滤器517过滤后，形成无菌空气，然后依次流经气管515和第一洁净层流装置514。经过滤后的无菌空气通过第一洁净层流装置514上的环形出风口排出，无菌空气在环形出风口处形成正压。形成正压的无菌空气环绕包围溶药器本体11和针头，形成气体屏蔽层流，气体屏蔽层流能够避免溶药器本体11 和针头与带有细菌的空气接触，增强了配药的安全性。Before the start of dispensing and during the dispensing process, the second air pump 518 pumps air into the purification device 516, and the air is filtered by the air filter 517 in the purification device 516 to form sterile air, which in turn flows through the air tube 515 and the first clean. Laminar flow device 514. The filtered sterile air is discharged through an annular vent on the first clean laminar flow device 514, and the sterile air forms a positive pressure at the annular vent. The sterile air forming a positive pressure surrounds the solvent body 11 and the needle to form a gas shield laminar flow, and the gas shield laminar flow can avoid the dissolver body 11 Contact with the air with bacteria to enhance the safety of the dispensing.
实施例五 Embodiment 5
本实施例提供的一种无菌配药***与实施例4的不同之处在于：所述前段推杆410一端设置有外螺纹，所述胶塞21尾端设置有与所述前段推杆410上的外螺纹相对应的内螺纹接头；通过所述前段推杆410一边前进一边绕轴旋转，将所述前段推杆410的外螺纹与所述胶塞21的内螺纹接头相旋合，从而使所述前段推杆410与所述胶塞21相结合。The present invention provides an aseptic dispensing system that differs from the fourth embodiment in that the front end push rod 410 is provided with an external thread at one end, and the rubber end 21 is provided with the front end push rod 410. Corresponding internal threaded joint; the front push rod 410 rotates about the axis while advancing, and the external thread of the front push rod 410 is screwed with the female threaded joint of the rubber plug 21, thereby The front stage push rod 410 is combined with the rubber plug 21.
实施例六Embodiment 6
本实施例提供的一种无菌配药***与实施例5的不同之处在于：所述无菌配药***上还设置有多个光电位置传感器，以及一个可以随着所述结合部运动的光电挡片610，通过所述光电位置传感器与所述光电挡片610的配合，可实现电路的通断从而控制所述推杆电机310和所述杆头旋转电机413转动；如图6所示，当所述光电挡片610与第一光电位置传感器510感应时，所述前段推杆410处于距离所述溶药器本体11的最远端位置，所述前段推杆410未伸入所述溶药器本体11内部，此时，所述胶塞21位于所述溶药器本体11的最前端；结合图7所示，所述前段推杆410在所述致动部的带动下，逐渐伸入所述溶药器本体11内部，当所述光电挡片610与第三光电位置传感器512感应时，所述前段推杆410与所述胶塞21上设置的外螺纹接头210尾端相接触，此时所述杆头旋转电机413启动，进而带动所述前段推杆410转动；结合图8所示，所述推杆电机310继续推动所述前段推杆410前进，同时所述杆头旋转电机413带动所述前段推杆410旋转，所述前段推杆410一边前进一边绕轴旋转，将所述前段推杆410的外螺纹与所述胶塞21的内螺纹接头相旋合，从而使所述前段推杆410与所述胶塞21相结合，当所述光电挡片610与第四光电位置传感器513感应时，所述前段推杆410与所述外螺纹接头210旋合固定，此时所述前段推杆410到达行程的最前端位置；结合图9所示，所述光电挡片610与第四光电位置传感器513感应时，所述推杆电机310开始反向转动，所述杆头旋转电机413停止转动，所述推杆电机310带动所述前段推杆410和所述胶塞21向后运动，当所述光电挡片610与第二光电位置传感器511感应时，所述胶塞21被带动到其运动行程的最远端位置，此时，配药药液被吸入所述溶药器本体11内部。An aseptic dispensing system provided by this embodiment is different from Embodiment 5 in that the aseptic dispensing system is further provided with a plurality of photoelectric position sensors, and a photoelectric block that can move along with the joint portion. The sheet 610, through the cooperation of the photoelectric position sensor and the photoelectric blocking piece 610, can realize the opening and closing of the circuit to control the rotation of the push rod motor 310 and the head rotating electric machine 413; as shown in FIG. When the photoelectric blocking piece 610 is induced by the first photoelectric position sensor 510, the front stage push rod 410 is at a farthest position from the solvent body 11 , and the front stage push rod 410 does not protrude into the solvent. Inside the body 11 , at this time, the rubber plug 21 is located at the foremost end of the solvent body 11; as shown in FIG. 7 , the front push rod 410 is gradually extended by the actuating portion. Inside the solvent body 11 , when the photoelectric blocking piece 610 and the third photoelectric position sensor 512 sense, the front stage push rod 410 is in contact with the tail end of the male threaded joint 210 disposed on the rubber plug 21 , At this time, the head rotating electric motor 413 is activated, thereby driving The front pusher 410 rotates; as shown in FIG. 8, the pusher motor 310 continues to push the front pusher 410 forward, while the head rotary motor 413 drives the front pusher 410 to rotate, the front push The rod 410 rotates about the axis while advancing, and the external thread of the front push rod 410 is screwed with the female threaded joint of the rubber plug 21, so that the front push rod 410 is combined with the rubber plug 21, When the photoelectric blocking piece 610 is sensed by the fourth photoelectric position sensor 513, the front stage push rod 410 is screwed and fixed to the external threaded joint 210, and the front stage push rod 410 reaches the foremost position of the stroke; As shown in FIG. 9, when the photoelectric blocking piece 610 and the fourth photoelectric position sensor 513 sense, the push rod motor 310 starts to rotate in the reverse direction, the head rotating electric machine 413 stops rotating, and the push rod motor 310 drives the center. The front push rod 410 and the rubber plug 21 move backward. When the photoelectric block 610 and the second photoelectric position sensor 511 sense, the rubber plug 21 is driven to the most distal position of the movement stroke thereof. At the time, the dispensing solution is drawn into the solvent body 1 1 internal.
实施例七Example 7
本实施例提供的一种无菌配药***与实施例6的不同之处在于：所述无菌配药***还包括有：The sterile dispensing system provided in this embodiment is different from the embodiment 6 in that the aseptic dispensing system further comprises:
便携手柄，其用于方便医疗人员握持和操作；Portable handle for easy access and operation by medical personnel;
主控电路，其用于接收所述光电挡片610与所述光电位置传感器感应时传输来的信号，并控制所述杆头旋转电机413和所述推杆电机310的启停；a main control circuit, configured to receive a signal transmitted by the photoelectric blocking piece 610 and the photoelectric position sensor, and control start and stop of the head rotating electric machine 413 and the push rod motor 310;
状态指示灯，其用于显示所述无菌配药***的工作状态，提示医疗人员进行合理的操作。A status indicator light for displaying the working status of the aseptic dispensing system, prompting the medical personnel to perform reasonable operations.
实施例八Example eight
本实施例提供的一种无菌配药***与实施例7的不同之处在于：在实际使用过程中，为了保证配药***处于无菌状态，避免不同药剂的掺杂，所述溶药器本体11和所述胶塞21均可设计为可拆卸的一次性使用部件，所述配药推杆同样可设计为可拆卸的一次性使用部件。An aseptic dispensing system provided in this embodiment is different from the embodiment 7 in that, in actual use, in order to ensure that the dispensing system is in a sterile state and avoid doping of different agents, the solvent body 11 Both the rubber plug 21 can be designed as a detachable disposable component, which can also be designed as a detachable disposable component.
采用所述前段推杆410与所述胶塞21相旋合的形式，可以将所述无菌配药***容易受污染的部分制作成一次性结构，如所述溶药器本体11和所述胶塞21；不易受污染的部分进行多次使用，如所述前段推杆410；其他不与药液接触的部件进行长期使用，定期消毒。且将所述前段推杆410与所述胶塞21分体设计，可节约一次性部件的浪费程度，每次使用后仅需替换所述溶药器本体11和所述胶塞21，而无需每次都替换所述前段推杆410，进而减少医疗垃圾，保护环境。The portion of the sterile dispensing system that is easily contaminated can be made into a disposable structure, such as the solvent body 11 and the glue, in a form in which the front pusher 410 is screwed into the rubber plug 21 The plug 21; the non-contaminated portion is used for multiple times, such as the front push rod 410; other parts that are not in contact with the liquid medicine are used for a long period of time and are periodically disinfected. And separating the front push rod 410 and the rubber plug 21 separately, the degree of waste of the disposable component can be saved, and only the solvent body 11 and the rubber plug 21 need to be replaced after each use, without The front pusher 410 is replaced each time, thereby reducing medical waste and protecting the environment.
实施例九Example nine
本实施例提供的一种无菌配药***与实施例8的不同之处在于：所述配药推杆为不可拆卸部件；所述配药推杆与所述致动部固定连接，所述配药推杆外设置的所 述套杆与所述致动部密封连接，保证所述无菌单元时刻处于无菌环境。An aseptic dispensing system provided in this embodiment is different from the embodiment 8 in that the dispensing pusher is a non-detachable component; the dispensing pusher is fixedly connected to the actuating portion, and the dispensing pusher External setting The sleeve is sealingly coupled to the actuation portion to ensure that the sterile unit is in a sterile environment at all times.
实施例十Example ten
如图10所示，为本发明无菌配药***的结构示意图；如图11所示，为本发明中第二手持部件内部结构示意图；如图12所示，为本发明中控制单元功能示意图。FIG. 10 is a schematic structural view of the aseptic dispensing system of the present invention; FIG. 11 is a schematic view showing the internal structure of the second hand-held component in the present invention; FIG. 12 is a schematic view showing the function of the control unit in the present invention. .
本实施例提供的一种无菌配药***，其包括：溶药单元，用于提供混合药剂的腔体；第二洁净层流装置，用于使所述溶药单元处在无菌环境中；动力单元，用于为所述溶药单元提供动力以及为第二洁净层流装置提供正压气体；第二手持部件，用于连接所述溶药单元和所述动力单元；控制单元，用于控制所述动力单元；除菌装置，除菌装置包括第一除菌装置407和第二除菌装置9。The present invention provides an aseptic dispensing system comprising: a drug dissolution unit for providing a cavity for mixing a medicament; and a second clean laminar flow device for placing the drug dissolution unit in a sterile environment; a power unit for powering the solvent-dissolving unit and providing a positive pressure gas for the second clean laminar flow device; a second hand-held component for connecting the solvent-dissolving unit and the power unit; and a control unit For controlling the power unit; the sterilization device, the sterilization device includes a first sterilization device 407 and a second sterilization device 9.
溶药单元包括溶药器本体11，溶药器本体11与第二手持部件40通过螺纹连接，所述动力单元为气泵7，第二手持部件40通过第一气管602与气泵7连通，控制单元8分别与第二手持部件40和气泵7电连接。The solvent-dissolving unit includes a drug dissolver body 11 that is screwed to the second hand-held component 40, the power unit is an air pump 7, and the second hand-held component 40 is in communication with the air pump 7 through the first air pipe 602. The control unit 8 is electrically connected to the second hand-held component 40 and the air pump 7, respectively.
所述溶药单元还包括注射针22、针托110和胶塞21，溶药器本体11的前端通过所述针托110与注射针22连接，溶药器本体11的尾端与所述第二手持部件40通过螺纹连接，胶塞21内置于溶药器本体11。The drug dissolution unit further includes an injection needle 22, a needle holder 110 and a rubber stopper 21, and the front end of the drug solution body 11 is connected to the injection needle 22 through the needle holder 110, and the tail end of the drug dissolver body 11 and the first The two hand-held members 40 are screwed together, and the rubber stopper 21 is built in the solvent body 11.
针托110为一中空的相对于溶药器本体向外凸起的柱状物，用于支撑注射针22，注射针22由固定单元固定在针托110内，所述固定单元可为橡胶软体、树脂软体等具有密闭作用的弹性体。The needle holder 110 is a hollow column that is outwardly convex relative to the body of the drug solution for supporting the injection needle 22. The injection needle 22 is fixed in the needle holder 110 by a fixing unit, and the fixing unit can be a rubber soft body. An elastomer having a sealing function such as a resin soft body.
溶药器本体11内表面呈圆柱状，胶塞21一端为圆柱状橡胶软体，另一端设有第一磁体，所述第一磁体为永磁体2101，胶塞21的外径与溶药器本体11内径相同。胶塞21在溶药器本体11内轴向运动。胶塞21将溶药器本体11内部分隔为溶药腔120和溶药器气腔140，溶药腔120和溶药器气腔140完全密闭隔离。The inner surface of the drug dissolver body 11 has a cylindrical shape, one end of the rubber plug 21 is a cylindrical rubber soft body, and the other end is provided with a first magnet, the first magnet is a permanent magnet 2101, the outer diameter of the rubber plug 21 and the solvent body 11 inner diameter is the same. The rubber stopper 21 moves axially within the dissolver body 11. The rubber plug 21 separates the inside of the solvent body 11 into a solvent cavity 120 and a solvent cavity 140, and the solvent cavity 120 and the solvent cavity 140 are completely sealed.
第二手持部件40包括手柄座405和手柄406，手柄406的一端与手柄座405通过第一螺纹50连接，手柄406的另一端通过气动接头403与第一气管602连接。手柄406上还设有第一按键和第二按键，第一按键为推送按键401，第二按键为抽吸按键402，推送按键401和抽吸按键402均与控制单元8电连接。手柄座405内部设有第二螺纹404，该螺纹用于将溶药器本体11的尾端固定在手柄座405上。手柄座还包括一密封胶垫502，密封胶垫502设置在溶药器本体11与手柄座405之间，其用于保障溶药器本体11与手柄座405之间连接的气密性。手柄406为内部中空结构。手柄406内部还设有第一除菌装置407和第二磁体。第一除菌装置407所使用的除菌材料至少包括聚丙烯，硅藻土，玻璃纤维，混合纤维素酯，聚偏二氟乙烯，聚四氟乙烯，聚醚矾，尼龙，纤维素酯，改良纤维素当中的一种或几种，第一除菌装置407的过滤孔径不超过0.22微米。第二磁体为电磁铁408，电磁铁408与控制单元8电连接。The second hand held component 40 includes a handle base 405 and a handle 406. One end of the handle 406 is coupled to the handle base 405 by a first thread 50, and the other end of the handle 406 is coupled to the first air tube 602 by a pneumatic joint 403. The first button and the second button are further disposed on the handle 406. The first button is a push button 401, the second button is a suction button 402, and the push button 401 and the suction button 402 are electrically connected to the control unit 8. The handle seat 405 is internally provided with a second thread 404 for securing the trailing end of the solvent body 11 to the handle seat 405. The handle base further includes a sealing rubber pad 502 disposed between the drug dissolver body 11 and the handle seat 405 for ensuring the airtightness of the connection between the drug dissolver body 11 and the handle seat 405. The handle 406 is an internal hollow structure. A first sterilization device 407 and a second magnet are also disposed inside the handle 406. The sterilization material used in the first sterilization device 407 includes at least polypropylene, diatomaceous earth, glass fiber, mixed cellulose ester, polyvinylidene fluoride, polytetrafluoroethylene, polyether oxime, nylon, cellulose ester, One or more of the modified cellulose, the filtration pore size of the first sterilization device 407 does not exceed 0.22 μm. The second magnet is an electromagnet 408 that is electrically connected to the control unit 8.
第二洁净层流装置501套装在第二手持部件40上，第二洁净层流装置501上设置环形出风口，第二洁净层流装置501通过第二气管601与气泵7连通，第二气管601上还设置第二除菌装置9和第二电磁阀603。第二除菌装置9内所使用的除菌材料至少包括聚丙烯，硅藻土，玻璃纤维，混合纤维素酯，聚偏二氟乙烯，聚四氟乙烯，聚醚矾，尼龙，纤维素酯，改良纤维素当中的一种或几种，第二除菌装置9的过滤孔径不超过0.22微米，第二除菌装置9用于过滤来自气泵7的气体。第二电磁阀603与控制单元8电连接。The second clean laminar flow device 501 is disposed on the second hand-held component 40. The second clean laminar flow device 501 is provided with an annular air outlet, and the second clean laminar flow device 501 is connected to the air pump 7 through the second air pipe 601. The second air pipe A second sterilization device 9 and a second electromagnetic valve 603 are also disposed on the 601. The sterilization material used in the second sterilization device 9 includes at least polypropylene, diatomaceous earth, glass fiber, mixed cellulose ester, polyvinylidene fluoride, polytetrafluoroethylene, polyether oxime, nylon, cellulose ester. One or more of the modified cellulose, the filtration pore size of the second sterilization device 9 is not more than 0.22 μm, and the second sterilization device 9 is for filtering the gas from the air pump 7. The second solenoid valve 603 is electrically connected to the control unit 8.
第二手持部件40通过第一气管602与气泵7连通，第一气管602上设置第一电磁阀604，第一电磁阀604与控制单元8电连接。The second hand-held component 40 is in communication with the air pump 7 through the first air tube 602. The first air tube 602 is provided with a first electromagnetic valve 604, and the first electromagnetic valve 604 is electrically connected to the control unit 8.
控制单元8分别与第一电磁阀604、第二电磁阀603、气泵7、电磁铁408、推送按键401和抽吸按键402电连接。The control unit 8 is electrically connected to the first electromagnetic valve 604, the second electromagnetic valve 603, the air pump 7, the electromagnet 408, the push button 401, and the suction button 402, respectively.
本实施例中无菌配药***工作原理：The working principle of the aseptic dispensing system in this embodiment:
首先，将溶药器本体11尾端与手柄座405固定连接在一起，然后按动推送按键401，此时，控制单元8控制第一电磁阀604和第二电磁阀603开启，控制单元8控制气泵7开始工作，气泵7开始向第一气管602和第二气管601泵入气体。进入第二气管601的气体依次通过第二电磁阀603和第二除菌装置9，最终通过第二 洁净层流装置501上的环形出风口排出，流经第二除菌装置9的气体经过过滤变成无菌气体，因此，从第二洁净层流装置501上的环形出风口排出的气体为无菌气体。该无菌空气在环形出风口处形成正压。形成正压的无菌空气环绕包围溶药器本体11和取药器2，形成气体屏蔽层流，气体屏蔽层流能够避免溶药器本体11和注射针22与带有细菌的空气接触，增强了配药的安全性。与此同时，进入第一气管602内的气体，依次流经第一电磁阀604和第一除菌装置407，进而流入溶药器气腔140，使得溶药器气腔140内气体压力升高，当溶药器气腔140内气体压力大于溶药腔内12内的压力时，溶药器气腔140内的高压气体推动胶塞21向远离气泵7方向运动，胶塞21向远离气泵7方向运动将溶药腔120内的空气全部排出，当溶药腔120内的空气全部排出后，将注射针22***液体药剂瓶中，然后按抽吸按键402，此时，控制单元8控制第二电磁阀603开启，第一电磁阀604关闭，气泵7开始向第二气管601泵入气体，进入第二气管601的气体依次通过第二电磁阀603和第二除菌装置9，最终通过第二洁净层流装置501上的环形出风口排出。与此同时，控制单元8控制电磁铁408通电，通电的电磁铁408产生电磁场，该电磁场使得电磁铁408与胶塞21中的永磁体2101之间产生吸引力，在磁力的作用下，胶塞21向靠近电磁铁408方向运动，进而使液体药剂瓶中的药液流入溶药腔120内，然后移除液体药剂瓶，将注射针22***冻干粉冻干粉药剂瓶中，再按动推送按键401，此时，控制单元8控制第一电磁阀604和第二电磁阀603开启，气泵7向第一气管602和第二气管601泵入气体。进入第二气管601的气体依次通过第二电磁阀603和第二除菌装置9，最终通过第二洁净层流装置501上的环形出风口排出。与此同时，进入第一气管602内的气体，依次流经第一电磁阀604和第一除菌装置407，进而流入溶药器气腔140，使得溶药器气腔140内气体压力升高，当溶药器气腔140内气体压力大于溶药腔内12内的压力时，溶药器气腔140内的高压气体推动胶塞21向远离气泵7方向运动，使溶药腔120内药液流入冻干粉药剂瓶中，待药液与冻干粉充分混合后，按抽吸按键402，此时，控制单元8控制第二电磁阀603开启，第一电磁阀604关闭，气泵7开始向第二气管601泵入气体，进入第二气管601的气体依次通过第二电磁阀603和第二除菌装置9，最终通过第二洁净层流装置501上的环形出风口排出。与此同时，控制单元8控制电磁铁408通电，通电的电磁铁408产生电磁场，该电磁场使得电磁铁408与胶塞21中的永磁体2101之间产生吸引力，在磁力的作用下，胶塞21向靠近电磁铁408方向运动，将冻干粉与药液的混合物抽取至溶药腔120内，完成溶药。无菌配药***工作过程中，溶药器气腔12内的空气始终保持为过滤后的无菌空气，防止溶药器本体11内部遭受污染，使溶药过程更加安全，同时，第二洁净层流装置501环形出风口处始终输出正压的无菌气体，使得气体屏蔽层流一直存在，使溶药器本体11、注射针22和药剂瓶处于无菌环境中。First, the tail end of the dissolver body 11 is fixedly coupled with the handle base 405, and then the push button 401 is pressed. At this time, the control unit 8 controls the first solenoid valve 604 and the second solenoid valve 603 to be opened, and the control unit 8 controls The air pump 7 starts to operate, and the air pump 7 starts pumping gas into the first air tube 602 and the second air tube 601. The gas entering the second gas pipe 601 passes through the second electromagnetic valve 603 and the second sterilization device 9, and finally passes through the second The annular air outlet on the clean laminar flow device 501 is discharged, and the gas flowing through the second sterilization device 9 is filtered to become a sterile gas, so that the gas discharged from the annular air outlet on the second clean laminar flow device 501 is none. Bacteria gas. The sterile air forms a positive pressure at the annular vent. The sterile air forming a positive pressure surrounds the solvent body 11 and the drug taker 2 to form a gas shield laminar flow, and the gas shield laminar flow can prevent the solvent body 11 and the injection needle 22 from contacting the air with bacteria, enhancing The safety of dispensing. At the same time, the gas entering the first gas pipe 602 flows through the first electromagnetic valve 604 and the first sterilization device 407, and then flows into the solvent chamber 140, so that the gas pressure in the solvent chamber 140 is raised. When the gas pressure in the solvent chamber 140 is greater than the pressure in the solvent chamber 12, the high pressure gas in the solvent chamber 140 pushes the rubber stopper 21 to move away from the air pump 7, and the rubber plug 21 moves away from the air pump 7 The directional movement discharges all the air in the solvent chamber 120. When the air in the solvent chamber 120 is completely discharged, the injection needle 22 is inserted into the liquid medicine bottle, and then the suction button 402 is pressed. At this time, the control unit 8 controls the first The second solenoid valve 603 is opened, the first electromagnetic valve 604 is closed, the air pump 7 starts to pump the gas into the second gas pipe 601, and the gas entering the second gas pipe 601 passes through the second electromagnetic valve 603 and the second sterilization device 9, and finally passes through the first The annular air outlet on the second clean laminar flow device 501 is discharged. At the same time, the control unit 8 controls the electromagnet 408 to be energized, and the energized electromagnet 408 generates an electromagnetic field which causes an attractive force between the electromagnet 408 and the permanent magnet 2101 in the rubber stopper 21, and under the action of the magnetic force, the rubber stopper 21 moves toward the electromagnet 408, thereby causing the liquid medicine in the liquid medicine bottle to flow into the drug solution chamber 120, then removing the liquid medicine bottle, inserting the injection needle 22 into the freeze-dried powder freeze-dried powder medicine bottle, and then pressing The button 401 is pushed, at which time the control unit 8 controls the first solenoid valve 604 and the second solenoid valve 603 to be opened, and the air pump 7 pumps the gas into the first gas pipe 602 and the second gas pipe 601. The gas entering the second gas pipe 601 is sequentially passed through the second electromagnetic valve 603 and the second sterilization device 9, and finally discharged through the annular air outlet on the second clean laminar flow device 501. At the same time, the gas entering the first gas pipe 602 flows through the first electromagnetic valve 604 and the first sterilization device 407, and then flows into the solvent chamber 140, so that the gas pressure in the solvent chamber 140 is raised. When the gas pressure in the solvent chamber 140 is greater than the pressure in the solvent chamber 12, the high pressure gas in the solvent chamber 140 pushes the rubber stopper 21 to move away from the air pump 7, so that the solvent is dissolved in the solvent chamber 120. The liquid flows into the lyophilized powder medicament bottle. After the drug solution is thoroughly mixed with the lyophilized powder, the suction button 402 is pressed. At this time, the control unit 8 controls the second solenoid valve 603 to open, the first solenoid valve 604 is closed, and the air pump 7 starts. The gas is pumped into the second gas pipe 601, and the gas entering the second gas pipe 601 is sequentially passed through the second electromagnetic valve 603 and the second sterilization device 9, and finally discharged through the annular air outlet on the second clean laminar flow device 501. At the same time, the control unit 8 controls the electromagnet 408 to be energized, and the energized electromagnet 408 generates an electromagnetic field which causes an attractive force between the electromagnet 408 and the permanent magnet 2101 in the rubber stopper 21, and under the action of the magnetic force, the rubber stopper 21 moves toward the electromagnet 408, and the mixture of the lyophilized powder and the medical solution is drawn into the dissolution chamber 120 to complete the dissolution. During the operation of the aseptic dispensing system, the air in the solvent chamber 12 is always kept as sterile air after filtration, preventing the interior of the body 11 from being contaminated, making the dissolution process safer, and at the same time, the second clean layer The positive pressure of the sterile gas is always output at the annular outlet of the flow device 501, so that the gas shield laminar flow is always present, so that the dissolver body 11, the injection needle 22 and the medicament bottle are in a sterile environment.
实施例十一 Embodiment 11
本实施例提供的一种无菌配药***与实施例8的不同之处在于：所述除菌装置只包括第三除菌装置，所述第三除菌装置一端通过气管分别与第一电磁阀604和第二电磁阀603连通，所述第三除菌装置的另一端与所述动力单元连接。An aseptic dispensing system provided in this embodiment is different from the embodiment 8 in that the sterilization device includes only a third sterilization device, and the third sterilization device passes through the air tube and the first electromagnetic valve respectively. 604 is in communication with the second solenoid valve 603, and the other end of the third sterilization device is coupled to the power unit.
实施例十二Example twelve
如图13所示，为本发明的溶药器本体的结构示意图。如图14所示，为本实施例的无菌配药***的溶药器的结构示意图。本实施例提供一种无菌配药***，其包括溶药器本体11，溶药器本体11一端设有第一连接部118，另一端设有第二连接部119。第一连接部118与第一净化装置51采用螺纹连接或卡扣连接或爪钩连接或旋扣连接或磁力连接。第二连接部119与注射针22采用螺纹连接或卡扣连接或爪钩连接或旋扣连接或磁力连接。胶塞21内置于溶药器本体11。胶塞21内部设有第一磁体，所述第一磁体为永磁体2101，胶塞21在溶药器本体11内轴向运动。胶塞21将溶药器本体11分隔成第一腔体150和第二腔体160。溶药器本体11外形为圆柱体或椭圆柱体或长方体或三棱柱体。FIG. 13 is a schematic view showing the structure of the drug dissolver body of the present invention. As shown in Fig. 14, it is a schematic structural view of a solvent dissolver of the aseptic dispensing system of the present embodiment. The present embodiment provides an aseptic dispensing system comprising a drug dissolver body 11 having a first connecting portion 118 at one end and a second connecting portion 119 at the other end. The first connecting portion 118 is connected to the first cleaning device 51 by a screw connection or a snap connection or a claw hook connection or a screw connection or a magnetic connection. The second connecting portion 119 is connected to the injection needle 22 by a screw connection or a snap connection or a claw hook connection or a screw connection or a magnetic connection. The rubber stopper 21 is built in the solvent body 11. A first magnet is disposed inside the rubber plug 21, and the first magnet is a permanent magnet 2101, and the rubber plug 21 moves axially within the solvent body 11. The rubber stopper 21 divides the drug dissolver body 11 into a first cavity 150 and a second cavity 160. The shape of the drug dissolver body 11 is a cylinder or an elliptical cylinder or a rectangular parallelepiped or a triangular prism.
第一净化装置51通过管道口52与外界空气连通，第一净化装置51内部还设 置气体管路53，气体管路53一端设有管道口52，另一端与第二腔体160连通，气体管路53上设有第一空气过滤器53，第一空气过滤器53用于过滤通过管道口52进入气体管路53的外界空气。第一空气过滤器53使进入第二腔体160的空气变为无菌空气。The first purification device 51 communicates with the outside air through the pipe port 52, and the first purification device 51 is further provided inside. The gas line 53 is provided with a pipe port 52 at one end and a second chamber 160 at the other end. The gas line 53 is provided with a first air filter 53 for filtering The outside air entering the gas line 53 through the duct opening 52. The first air filter 53 causes the air entering the second chamber 160 to become sterile air.
第一净化装置51与第一连接部118连接处设有密封圈54。气体管路53与溶药器本体11连通一端的截面积小于胶塞21的截面积，其好处在于，防止胶塞21脱离溶药器本体11而进入气体管路53内。第一净化装置51内固定安装有第二磁体，所述第二磁体为电磁铁55，电磁铁55用于驱动永磁体2101运动，进而驱动胶塞21运动。当电磁铁55不通电时，永磁体2101位置保持不变，当电磁铁55正向通电时，电磁铁55和永磁体2101之间产生斥力，当电磁铁55反向通电时，电磁铁55和永磁体2101之间产生吸引力。A seal ring 54 is provided at the junction of the first purification device 51 and the first connection portion 118. The cross-sectional area of the end of the gas line 53 communicating with the solvent body 11 is smaller than the cross-sectional area of the rubber plug 21, which has the advantage of preventing the rubber stopper 21 from coming out of the solvent body 11 and entering the gas line 53. The second cleaning device 51 is fixedly mounted with a second magnet, and the second magnet is an electromagnet 55 for driving the permanent magnet 2101 to move, thereby driving the rubber stopper 21 to move. When the electromagnet 55 is not energized, the position of the permanent magnet 2101 remains unchanged. When the electromagnet 55 is energized in the forward direction, a repulsive force is generated between the electromagnet 55 and the permanent magnet 2101. When the electromagnet 55 is reversely energized, the electromagnet 55 and An attractive force is generated between the permanent magnets 2101.
本实施例提供的一种无菌配药***还包括第三洁净层流装置10，第三洁净层流装置10套装在第一净化装置51上，第三洁净层流装置10上设置环形出风口，第三洁净层流装置10通过气管58与第二净化装置56连通，第二空气过滤器57内置于第二净化装置56中，第二空气过滤器57用于过滤来自第三气泵59的气体，第三气泵59通过管道与第二净化装置56连通。The aseptic dispensing system provided in this embodiment further includes a third clean laminar flow device 10, the third clean laminar flow device 10 is set on the first purifying device 51, and the third clean laminar flow device 10 is provided with an annular air outlet. The third clean laminar flow device 10 is in communication with the second purifying device 56 through the air tube 58 , the second air filter 57 is built in the second purifying device 56 , and the second air filter 57 is used to filter the gas from the third air pump 59 . The third air pump 59 is in communication with the second purification device 56 via a conduit.
本实施例的工作原理为：The working principle of this embodiment is as follows:
配药开始前，启动第三气泵59，第三气泵59向第二净化装置56泵入空气，空气经第二空气过滤器57过滤后，依次流经气管58和第三洁净层流装置10。无菌空气通过第三洁净层流装置10上的环形出风口排出，无菌空气在环形出风口处形成正压。形成正压的无菌空气环绕包围溶药器本体11和注射针22，形成气体屏蔽层流，气体屏蔽层流能够避免溶药器本体11和注射针22与带有细菌的空气接触，增强了配药的安全性。Before the start of dispensing, the third air pump 59 is activated, and the third air pump 59 pumps air into the second purifying device 56, and the air is filtered through the second air filter 57, and then sequentially flows through the air tube 58 and the third clean laminar flow device 10. The sterile air is discharged through the annular air outlet on the third clean laminar flow device 10, and the sterile air forms a positive pressure at the annular air outlet. The sterile air forming a positive pressure surrounds the solvent body 11 and the injection needle 22 to form a gas shield laminar flow, and the gas shield laminar flow can prevent the solvent body 11 and the injection needle 22 from coming into contact with the air with bacteria, thereby enhancing The safety of dispensing.
将溶药器本体11与第一净化装置51密闭连接，连接后，电磁铁55正向通电，电磁铁55产生的电磁场驱动永磁体2101向靠近注射针22的方向运动，同时，外界空气通过管道口52进入气体管路53内，经第一空气过滤器53过滤后，变为无菌空气，无菌空气进而进入第二腔体160。永磁体2101向靠近注射针22的方向运动过程中会将第一腔体150内的空气排出，当第一腔体150内的空气全部排出时，将注射针22***液体药剂瓶中，然后使电磁铁55反向通电，电磁铁55反向通电后产生的电磁场，驱动永磁体2101向远离注射针22的方向运动，进而使胶塞21向靠近第一净化装置51方向运动，将药液吸入第一腔体150内。然后移除液体药剂瓶，再将注射针22***冻干粉药剂瓶中，控制电磁铁55正向通电，电磁铁55正向通电产生的电磁场驱动永磁体2101向靠近注射针22的方向运动，使第一腔体150内的药液流入冻干粉药剂瓶中，待药液与冻干粉充分混合后，使电磁铁55反向通电，电磁铁55反向通电后产生的电磁场，驱动永磁体2101向远离注射针22的方向运动，进而使胶塞21向靠近第一净化装置51方向运动，进而，将冻干粉与药液的混合物抽取至第一腔体150内，完成配药。The solvent body 11 is hermetically connected to the first purification device 51. After the connection, the electromagnet 55 is energized in the forward direction, and the electromagnetic field generated by the electromagnet 55 drives the permanent magnet 2101 to move toward the injection needle 22, and the outside air passes through the pipeline. The port 52 enters the gas line 53 and is filtered by the first air filter 53 to become sterile air, which in turn enters the second chamber 160. The permanent magnet 2101 discharges the air in the first cavity 150 during the movement toward the injection needle 22. When the air in the first cavity 150 is completely discharged, the injection needle 22 is inserted into the liquid medicament bottle, and then The electromagnet 55 is energized in the reverse direction, and the electromagnetic field generated by the electromagnet 55 is reversely energized to drive the permanent magnet 2101 to move away from the injection needle 22, thereby moving the rubber stopper 21 toward the first purification device 51 to inhale the liquid. Inside the first cavity 150. Then, the liquid medicine bottle is removed, and the injection needle 22 is inserted into the lyophilized powder medicine bottle, the control electromagnet 55 is energized in the forward direction, and the electromagnetic field generated by the electromagnet 55 is energized to drive the permanent magnet 2101 to move toward the injection needle 22. The chemical solution in the first cavity 150 is caused to flow into the lyophilized powder drug bottle, and after the drug solution and the lyophilized powder are sufficiently mixed, the electromagnet 55 is reversely energized, and the electromagnetic field generated by the electromagnet 55 is reversely energized to drive the permanent The magnet 2101 moves in a direction away from the injection needle 22, thereby moving the rubber stopper 21 toward the first purification device 51, and further extracting the mixture of the lyophilized powder and the medical solution into the first cavity 150 to complete the dispensing.
配药***工作过程中，由于气体管路53上设有第一空气过滤器53，因此流入第二腔体160内的空气为净化后的无菌空气，防止溶药器本体11内部遭受污染，使配药过程更加安全。在整个配药***工作过程中，第三气泵59始终保持工作状态，使得气体屏蔽层流一直存在，以保证溶药器本体11、注射针22和药剂瓶处于无菌环境中。During the operation of the dispensing system, since the first air filter 53 is disposed on the gas line 53, the air flowing into the second chamber 160 is purified as sterile air, preventing the interior of the solvent body 11 from being contaminated. The dispensing process is safer. During operation of the dispensing system, the third air pump 59 is always in operation so that the gas barrier laminar flow is always present to ensure that the drug injector body 11, the injection needle 22 and the medicament bottle are in a sterile environment.
实施例十三Example thirteen
如图13所示，为本发明的溶药器本体的结构示意图，如图15所示，为本实施例的无菌配药***的溶药器的结构示意图。本实施例提供一种无菌配药***，其包括包括溶药器本体11，溶药器本体11一端设有第一连接部118，另一端设有第二连接部119。第一连接部118与第一净化装置51采用螺纹连接或卡扣连接或爪钩连接或旋扣连接或磁力连接。第二连接部119与注射针22采用螺纹连接或卡扣连接或爪钩连接或旋扣连接或磁力连接。胶塞21内置于溶药器本体11。胶塞21在溶药器本体11内轴向运动。胶塞21将溶药器本体11分隔成第一腔体150和第二腔体 160。制作胶塞21所使用的材料为耐高温且具有生物安全性的硅橡胶。溶药器本体11外形为圆柱体或椭圆柱体或长方体或三棱柱体。As shown in FIG. 13, it is a schematic structural view of the main body of the drug solution of the present invention, as shown in FIG. 15, which is a schematic structural view of the drug dissolver of the aseptic dispensing system of the present embodiment. The present embodiment provides an aseptic dispensing system comprising a drug dissolver body 11 having a first connecting portion 118 at one end and a second connecting portion 119 at the other end. The first connecting portion 118 is connected to the first cleaning device 51 by a screw connection or a snap connection or a claw hook connection or a screw connection or a magnetic connection. The second connecting portion 119 is connected to the injection needle 22 by a screw connection or a snap connection or a claw hook connection or a screw connection or a magnetic connection. The rubber stopper 21 is built in the solvent body 11. The rubber stopper 21 moves axially within the dissolver body 11. The rubber plug 21 divides the solvent body 11 into a first cavity 150 and a second cavity 160. The material used to make the rubber plug 21 is a high temperature resistant and biosafety silicone rubber. The shape of the drug dissolver body 11 is a cylinder or an elliptical cylinder or a rectangular parallelepiped or a triangular prism.
第一净化装置51通过接头52与第三气泵60连通，第一净化装置51内部还设置气体管路53，气体管路53一端与接头52连通，另一端与第二腔体160连通，气体管路53上设有第一空气过滤器53，第一空气过滤器53用于过滤来自第三气泵60的气体，第一空气过滤器53使来自第三气泵60的空气变为无菌空气。The first purifying device 51 is in communication with the third air pump 60 through the joint 52. The first purifying device 51 is further provided with a gas line 53. One end of the gas line 53 communicates with the joint 52, and the other end communicates with the second chamber 160. The gas tube The path 53 is provided with a first air filter 53 for filtering the gas from the third air pump 60, and the first air filter 53 causes the air from the third air pump 60 to become sterile air.
第一净化装置51与第一连接部118连接处设有密封圈54。气体管路53与溶药器本体11连通一端的截面积小于胶塞21的截面积，其好处在于，防止胶塞21脱离溶药器本体11而进入气体管路53内。A seal ring 54 is provided at the junction of the first purification device 51 and the first connection portion 118. The cross-sectional area of the end of the gas line 53 communicating with the solvent body 11 is smaller than the cross-sectional area of the rubber plug 21, which has the advantage of preventing the rubber stopper 21 from coming out of the solvent body 11 and entering the gas line 53.
本实施例提供的一种无菌配药***还包括第四洁净层流装置100，第四洁净层流装置100套装在第一净化装置51上，第四洁净层流装置100上设置环形出风口，第四洁净层流装置100通过气管17与第二净化装置56连通，第二空气过滤器57内置于第二净化装置56中，第二空气过滤器57用于过滤来自第四气泵59的气体，第四气泵59通过管道与第二净化装置56连通。The aseptic dispensing system provided in this embodiment further includes a fourth clean laminar flow device 100, the fourth clean laminar flow device 100 is set on the first purifying device 51, and the fourth clean laminar flow device 100 is provided with an annular air outlet. The fourth clean laminar flow device 100 communicates with the second purifying device 56 through the air tube 17, the second air filter 57 is built in the second purifying device 56, and the second air filter 57 is used to filter the gas from the fourth air pump 59. The fourth air pump 59 is in communication with the second purification device 56 through a conduit.
本实施例的工作原理为：The working principle of this embodiment is as follows:
配药开始前，启动第四气泵59，第四气泵59向第二净化装置56泵入空气，空气经第二空气过滤器57过滤后，依次流经气管17和第四洁净层流装置100。无菌空气通过第四洁净层流装置100上的环形出风口排出，无菌空气在环形出风口处形成正压。形成正压的无菌空气环绕包围溶药器本体11和注射针22，形成气体屏蔽层流，气体屏蔽层流能够避免溶药器本体11和注射针22与带有细菌的空气接触，增强了配药的安全性。Before the start of dispensing, the fourth air pump 59 is activated, and the fourth air pump 59 pumps air into the second purifying device 56, and the air is filtered through the second air filter 57, and then sequentially flows through the air tube 17 and the fourth clean laminar flow device 100. The sterile air is discharged through the annular air outlet on the fourth clean laminar flow device 100, and the sterile air forms a positive pressure at the annular air outlet. The sterile air forming a positive pressure surrounds the solvent body 11 and the injection needle 22 to form a gas shield laminar flow, and the gas shield laminar flow can prevent the solvent body 11 and the injection needle 22 from coming into contact with the air with bacteria, thereby enhancing The safety of dispensing.
将溶药器本体11与第一净化装置51密闭连接，连接后，第三气泵60向气体管路53内压入空气，由于气体管路53与第二腔体160连通，因此第二腔体160内气压升高，当第二腔体160内的气压高于第一腔体150时，第二腔体160内的高压气体推动活塞向靠近注射针22方向运动。将第一腔体150内的空气全部排出，当第一腔体150内的空气全部排出时，将注射针22***液体药剂瓶中，然后通过第三气泵60将第二腔体160内的气体吸出，当第一腔体150内的压力大于第二腔体160内的压力时，胶塞21向靠近第一净化装置51方向运动，将药液吸入第一腔体150内。然后移除液体药剂瓶，再将注射针22***冻干粉药剂瓶中，控制第三气泵60向气体管路53内压入空气，当第二腔体160内的气压高于第一腔体150时，第二腔体160内的高压气体推动活塞向靠近注射针22方向运动，使第一腔体150内的药液流入冻干粉药剂瓶中，待药液与冻干粉充分混合后，通过第三气泵60将第二腔体160内的气体吸出，当第一腔体150内的压力大于第二腔体160内的压力时，胶塞21向靠近第一净化装置51方向运动，进而，将冻干粉与药液的混合物抽取至第一腔体150内，完成配药。The solvent body 11 is hermetically connected to the first purification device 51. After the connection, the third air pump 60 presses air into the gas line 53. Since the gas line 53 communicates with the second chamber 160, the second chamber The gas pressure in 160 rises. When the gas pressure in the second chamber 160 is higher than the first chamber 150, the high pressure gas in the second chamber 160 pushes the piston to move toward the injection needle 22. The air in the first cavity 150 is completely discharged. When the air in the first cavity 150 is completely discharged, the injection needle 22 is inserted into the liquid medicine bottle, and then the gas in the second cavity 160 is passed through the third air pump 60. When the pressure in the first cavity 150 is greater than the pressure in the second cavity 160, the rubber stopper 21 moves toward the first cleaning device 51 to suck the liquid into the first cavity 150. Then, the liquid medicine bottle is removed, and the injection needle 22 is inserted into the lyophilized powder medicine bottle, and the third air pump 60 is controlled to press air into the gas line 53. When the air pressure in the second chamber 160 is higher than the first chamber At 150 o'clock, the high pressure gas in the second cavity 160 pushes the piston to move closer to the injection needle 22, so that the liquid medicine in the first cavity 150 flows into the lyophilized powder medicine bottle, and the drug solution is thoroughly mixed with the lyophilized powder. The gas in the second cavity 160 is sucked out by the third air pump 60. When the pressure in the first cavity 150 is greater than the pressure in the second cavity 160, the rubber plug 21 moves toward the first cleaning device 51. Further, the mixture of the lyophilized powder and the drug solution is drawn into the first cavity 150 to complete the dispensing.
配药***工作过程中，由于气体管路53上设有第一空气过滤器53，因此流入第二腔体160内的空气为净化后的无菌空气，防止溶药器本体11内部遭受污染，使配药过程更加安全。During the operation of the dispensing system, since the first air filter 53 is disposed on the gas line 53, the air flowing into the second chamber 160 is purified as sterile air, preventing the interior of the solvent body 11 from being contaminated. The dispensing process is safer.
在整个配药***工作过程中，第四气泵59始终保持工作状态，使得气体屏蔽层流一直存在，以保证溶药器本体11、注射针22和药剂瓶处于无菌环境中。During the operation of the dispensing system, the fourth air pump 59 is always in operation, so that the gas barrier laminar flow is always present to ensure that the drug solution body 11, the injection needle 22 and the medicament bottle are in a sterile environment.
实施例十四 Embodiment 14
如图16-20所示，气源输出装置为一箱体结构，其内部被一隔热层70分为上部箱体和下部箱体，形成两个相对密封环境，隔热层具有隔热的功效，防止由于气泵，电源等设备工作时产生的大量热量对设备造成不必要的损伤。As shown in Figure 16-20, the air source output device is a box structure, and the inside is divided into an upper box and a lower box by a heat insulating layer 70 to form two relatively sealed environments, and the heat insulating layer is insulated. Efficacy, to prevent unnecessary damage to the equipment caused by a large amount of heat generated by the operation of the air pump, power supply and other equipment.
下部箱体内部设有一主工作泵79，主工作泵79加装有除油、除水的过滤装置，以保证设备的清洁度及高性能工作状态。上部箱体上设有开关71，用来产生小电流。主工作泵侧方设有触发装置81，其接受来自小电流的刺激，产生大电流，以此控制气源输出装置电路的通断。通常电气设备只设有一个按钮总管作为开关，按下即为打开，但是这种简单的开关会导致流入设备的工作电流较大，不够安全。如图19所示，触发装置为继电器，按下开关71后，产生的小电流刺激继电器24，使其线 圈两端被加上一定的电压，线圈中流过一定的电流，从而产生电磁效应，衔铁就会在电磁力的吸引下克服弹簧作用吸向铁芯，从而带动衔铁的动触点与静触点吸合，使其接通电路；关闭时，先关闭开关71，继电器的线圈断电，电磁的引力也随之消失，衔铁就会在弹簧的反作用力下返回原来的位置，使动触点与静触点释放，将电路断开。这样通过触点间的吸和、释放，从而达到了电路中的导通和切断的目的。开关和继电器的结合的作用在于：利用小电流控制大电流，这样通过设备的电流会有一个缓冲，不会急剧的变大或变小，极大的保证了设备的安全。A main working pump 79 is disposed inside the lower casing, and the main working pump 79 is equipped with a filtering device for removing oil and water to ensure the cleanliness and high performance working condition of the equipment. A switch 71 is provided on the upper casing for generating a small current. The side of the main working pump is provided with a triggering device 81, which receives stimulation from a small current and generates a large current, thereby controlling the on/off of the circuit of the gas source output device. Usually, the electric device only has one button main pipe as the switch, and the push is opened, but this simple switch causes the working current flowing into the device to be large and not safe enough. As shown in FIG. 19, the trigger device is a relay, and after the switch 71 is pressed, the generated small current stimulates the relay 24 to make its line A certain voltage is applied to both ends of the ring, a certain current flows through the coil, thereby generating an electromagnetic effect, and the armature is attracted to the iron core against the action of the spring under the attraction of the electromagnetic force, thereby driving the movable contact and the static contact of the armature. When the switch is closed, the switch 71 is turned off, the switch of the relay is turned off, the electromagnetic attraction is also lost, and the armature returns to the original position under the reaction force of the spring, so that the movable contact and the movable contact The static contact is released and the circuit is disconnected. In this way, through the suction and release between the contacts, the purpose of turning on and off in the circuit is achieved. The combination of the switch and the relay is to control the large current with a small current, so that the current through the device will have a buffer, which will not become sharply larger or smaller, which greatly ensures the safety of the device.
主工作泵79的前方为一稳压器80，用来输出稳定的电压供气源输出装置工作，防止由于电压不稳产生火花、损坏电路等情况的发生。稳压器80包括调压电路，控制电路及伺服电机，当输入电压或负载变化时，控制电路进行取样、比较、放大，然后驱动伺服电机转动，使调压器碳刷的位置改变，通过自动调整线圈匝数比，从而保持输出电压的稳定。主工作泵79的下方设有四个减震垫87，其用来减轻主工作泵79的震动，保证气源输出装置的整体稳定性。The front of the main working pump 79 is a voltage regulator 80 for outputting a stable voltage supply to the gas source output device to prevent sparks from occurring due to voltage instability, damage to the circuit, and the like. The voltage regulator 80 includes a voltage regulating circuit, a control circuit and a servo motor. When the input voltage or load changes, the control circuit samples, compares, and amplifies, and then drives the servo motor to rotate, so that the position of the voltage brush of the voltage regulator is changed through automatic Adjust the turns ratio of the coil to keep the output voltage stable. Below the main working pump 79 are provided four damping pads 87 for mitigating the vibration of the main working pump 79 and ensuring the overall stability of the gas source output device.
由于主工作泵79，继电器24，稳压器80均为大功率设备，工作时会产生大量的热量，所以在下部箱体背部设置两个风扇84用来散热，风扇84的进气口在下部箱体背面壳体上，出气口在两侧，这样的结构设计有利于内部空气流通，散热效果最好。另外，风扇84的进气口处设有低效过滤器，滤料为100％合成纤维，低效过滤器能够将空气中的较大颗粒、毛发等杂质过滤掉，防止其进入气源输出装置，对其内部设备造成损害，并造成环境污染。Since the main working pump 79, the relay 24, and the voltage regulator 80 are all high-power devices, a large amount of heat is generated during operation, so two fans 84 are disposed on the back of the lower casing for heat dissipation, and the air inlet of the fan 84 is at the lower portion. On the back side of the box body, the air outlet is on both sides. This structural design is beneficial to the internal air circulation and has the best heat dissipation effect. In addition, the air inlet of the fan 84 is provided with an inefficient filter, the filter material is 100% synthetic fiber, and the inefficient filter can filter out impurities such as larger particles and hair in the air to prevent it from entering the air source output device. , causing damage to its internal equipment and causing environmental pollution.
隔热层70上设有一中效过滤器3131，其进气口在隔热层的下方，抽取下部箱体内经低效过滤器过滤的空气，并有效去除各设备在较高温度环境下产生的水蒸气和油蒸气，避免蒸气遇冷后凝结为水汽，影响整体的清洁度及设备的正常使用。中效过滤器3131利用微粒的惯性和扩散作用，静电作用以及化学过滤作用对空气进行过滤，其结构稳定，具有较好的净化功能。主工作泵79的进气经过中效过滤器3131进行抽取，主工作泵79的出口设在上部箱体内。主工作泵一直保持启动的状态，一方面，若使用时才启动，会有延迟，另一方面，开关的时候会产生电火花，降低使用寿命，增加使用成本。The heat insulation layer 70 is provided with an intermediate effect filter 3131. The air inlet is below the heat insulation layer, and the air filtered by the inefficient filter in the lower box is extracted, and the equipment is effectively removed under a higher temperature environment. Water vapor and oil vapor, to avoid condensation of water into water vapor after cooling, affecting the overall cleanliness and normal use of equipment. The medium efficiency filter 3131 utilizes the inertia and diffusion of the particles, electrostatic action and chemical filtration to filter the air, and has a stable structure and a good purification function. The intake of the main working pump 79 is extracted through the intermediate effect filter 3131, and the outlet of the main working pump 79 is disposed in the upper casing. The main working pump is always in the state of starting. On the one hand, if it is started when it is used, there will be a delay. On the other hand, when the switch is started, an electric spark will be generated, the service life will be reduced, and the use cost will be increased.
下部箱体底部与隔热层70之间设有支撑结构82，其用来支撑隔热层70。如图19所示，支撑结构为至少一根支柱261，其上端与隔热层螺纹连接，下端与下部箱体底部螺纹连接。立柱节省空间，为主工作泵，继电器，稳压器的散热提供了便利，大大提高了气源输出装置工作的安全性。支柱最好采用钣金材质，因为其具有较好的刚度，不易折断、变形，能起到很好的支撑作用，另外，钣金材质的支柱能有效抵御气泵、继电器等设备工作产生的震动，大大提高气源输出装置的整体稳固性。A support structure 82 is provided between the bottom of the lower case and the heat insulating layer 70 for supporting the heat insulating layer 70. As shown in FIG. 19, the support structure is at least one post 261, the upper end of which is screwed to the heat insulating layer, and the lower end is screwed to the bottom of the lower case. The column saves space and facilitates the heat dissipation of the main working pump, relay and voltage regulator, greatly improving the safety of the working of the gas source output device. The pillar is preferably made of sheet metal, because it has good rigidity, is not easy to be broken and deformed, and can play a good supporting role. In addition, the pillar of sheet metal can effectively resist the vibration generated by the work of air pump, relay and other equipment. Greatly improve the overall stability of the gas source output device.
支柱的位置不限于图18中隔热层的四个顶点处，也可以为下部箱体底部与隔热层之间的其他位置，例如：下部箱体底部各边中点等便于安装支柱的位置，为提高整体稳固性，可在下部箱体底部与隔热层之间设置多根立柱。The position of the pillar is not limited to the four vertices of the heat insulation layer in FIG. 18, and may be other positions between the bottom of the lower tank and the heat insulation layer, for example, the middle point of each side of the bottom of the lower tank body and the like for facilitating the installation of the pillar. In order to improve the overall stability, a plurality of columns can be arranged between the bottom of the lower tank and the heat insulation layer.
上部箱体内的空气是由主工作泵79经过中效过滤器3131进行抽取的，所以相对比较干净。上部箱体内设有净化子装置，与主工作泵相比，净化子装置用于输出平稳、缓和的小流量洁净空气，主工作泵用于输出大流量洁净空气，可作为一种动力源。上部箱体还设有第二电磁阀73，第三电磁阀74，净化子装置包括：净化泵、第一电磁阀，上述三个电磁阀在隔热层70上依次排开。净化泵抽取上部箱体内部的空气，净化后的空气通过软管输出气源输出装置。第一电磁阀为二通电磁阀，设置在净化泵的输气管道上，用来控制气道的开闭。第二电磁阀73与第三电磁阀74为三通电磁阀，设置在主工作泵79的输气管道上，用来控制不同输气方向气道的开闭，第二电磁阀所在气道的输气方向为：由内至外，第三电磁阀所在气道的输气方向为：由外至内。The air in the upper tank is extracted by the main working pump 79 through the intermediate effect filter 3131, so it is relatively clean. The upper tank is provided with a purifying device. Compared with the main working pump, the purifying device is used for outputting a smooth and gentle flow of clean air, and the main working pump is used for outputting a large flow of clean air, which can be used as a power source. The upper casing is further provided with a second electromagnetic valve 73, a third electromagnetic valve 74, and the purifying sub-assembly comprises: a purging pump and a first electromagnetic valve, and the three electromagnetic valves are sequentially arranged on the thermal insulation layer 70. The purifying pump extracts the air inside the upper tank, and the purified air is output to the air source output device through the hose. The first solenoid valve is a two-way solenoid valve disposed on the gas pipeline of the purification pump for controlling the opening and closing of the air passage. The second solenoid valve 73 and the third solenoid valve 74 are three-way solenoid valves disposed on the gas pipeline of the main working pump 79 for controlling the opening and closing of the air passages in different gas transmission directions, and the air passages of the second electromagnetic valve are located. The direction of gas transmission is: from the inside to the outside, the gas direction of the airway where the third solenoid valve is located is: from the outside to the inside.
净化子装置的下端为一电路板78，气源输出装置设备间采用蓝牙连接，电路板78用来将上传的数据功能集成在里面，可以上传使用次数等信息。另外，可以在气源输出装置的各个位置安装传感器，通过传感器的数据判断***的工作状态，便于维修。上部箱体的壳体上设有小的出气口，用于将多余的气体排出，由于主工作泵 79不断地向上部箱体输送气体，会导致内部气压升高，所以出气口用来平衡气压。上部箱体的背面壳体上设有挂钩77，可用来手持气源输出装置，或将其悬挂在墙上等地方，为使用者的工作提供便利。The lower end of the purifying device is a circuit board 78, and the air source output device is connected by Bluetooth. The circuit board 78 is used to integrate the uploaded data function, and can upload information such as the number of times of use. In addition, sensors can be installed at various positions of the gas source output device, and the working state of the system can be judged by the data of the sensor, which is convenient for maintenance. The upper casing has a small air outlet on the casing for discharging excess gas due to the main working pump 79 Constantly transporting gas to the upper tank will cause the internal air pressure to rise, so the air outlet is used to balance the air pressure. The back casing of the upper casing is provided with a hook 77, which can be used for holding the air source output device or hanging it on a wall or the like to facilitate the user's work.
气源输出装置的输出口76设置在上部箱体的侧面，输出口76包括一气路输出口，气源输出装置与外界可采用有线或无线通讯，若为有线通讯，输出口还包括一电路输出口，用于电路连接。输出口设置在侧面不会影响整体的美观性，也避免有清洁死角，给清洁工作带来不便。The output port 76 of the air source output device is disposed on the side of the upper box, and the output port 76 includes a gas path output port. The gas source output device can be wired or wirelessly communicated with the outside world. If wired communication, the output port further includes a circuit output. Port for circuit connection. The setting of the output port on the side does not affect the overall aesthetics, and also avoids the cleaning dead angle, which brings inconvenience to the cleaning work.
气源输出装置的工作原理为：The working principle of the gas source output device is:
如图21所示，其为气源输出装置内气体流通示意图。主工作泵79一直处于工作状态，当第二电磁阀73和第三电磁阀74均为关闭状态时，空气沿中效过滤器31，B1，B2，进气口，出气口，A2，A1流动，净化泵抽取上部箱体内的空气，第一电磁阀控制气道的通断，空气经由三通，最终从输出口76输出，输出的空气为平稳、缓和的小流量洁净空气；当第二电磁阀打开时，空气沿中效过滤器31、B1、B2、进气口、出气口、A2、A3、C2、C3流动，最终从输出口76输出，输出的为大流量洁净空气，可作为一种动力源；当第三电磁阀74打开时，空气从输出口76输入，沿C3、C2、B3、B2、进气口、出气口、A2、A1流动，将空气抽进气源输出装置，过滤后运送到上部箱体内，并在需要的时候进行排出。主工作泵79和净化子装置，作为两种不同的气源输出端，可提供小流量、平稳的洁净空气，又可提供大流量、可作为动力源的洁净空气，使用者可根据实际需要对其进行选择，具有很强的实用性。另外，换新时可单独更换，使用起来方便有效，又不至于成本太高。As shown in FIG. 21, it is a schematic diagram of gas flow in the gas source output device. The main working pump 79 is always in the working state. When the second electromagnetic valve 73 and the third electromagnetic valve 74 are both closed, the air flows along the intermediate effect filter 31, B1, B2, the air inlet, the air outlet, A2, A1. The purging pump extracts the air in the upper tank, the first solenoid valve controls the opening and closing of the air passage, the air passes through the tee, and finally outputs from the output port 76, and the output air is a smooth and gentle small flow clean air; When the valve is opened, the air flows along the intermediate effect filter 31, B1, B2, the air inlet, the air outlet, A2, A3, C2, C3, and finally outputs from the output port 76, and the output is a large flow of clean air, which can be used as a When the third electromagnetic valve 74 is opened, the air is input from the output port 76, flows along the C3, C2, B3, B2, the air inlet, the air outlet, the A2, the A1, and the air is drawn into the air source output device. After filtration, it is transported to the upper tank and discharged as needed. The main working pump 79 and the purifying sub-device, as two different gas source output terminals, can provide a small flow, smooth clean air, and can provide a large flow, clean air that can be used as a power source, and the user can It is very practical for its selection. In addition, it can be replaced separately when it is renewed, it is convenient and effective to use, and it is not too expensive.
实施例十五Example fifteen
如图22所示，本发明提供一种无菌配药***，该***除了具有气源输出装置外，输出口76连接有一手柄86，手柄的另一端上可拆卸的装有溶药器85，气源输出装置将洁净的空气通过手柄86进行输送。手柄内设有一高效过滤器，对来自气源输出装置的空气再进行一次净化，目的是保证注入溶药器的是无菌空气。As shown in FIG. 22, the present invention provides an aseptic dispensing system. In addition to the air source output device, the output port 76 is connected with a handle 86, and the other end of the handle is detachably filled with a solvent dissolver 85. The source output device delivers clean air through the handle 86. A high-efficiency filter is provided in the handle to purify the air from the air source output device in order to ensure that the solvent is injected into the solvent.
手柄上设有检测装置，其为一光电传感器，溶药器上设有遮光带，光电传感器与遮光带配合使用，用来检测溶药器是否已安装到指定位置。检测装置检测到手柄上没有安装溶药器时，第一电磁阀打开，净化泵工作，手柄前端保持小动力洁净空气的吹出，将手柄前端置换为洁净无菌的环境，防止有菌空气对溶药器，药物造成污染。当检测到溶药器已安装在手柄上时，第一电磁阀断开，净化泵停止工作。The handle is provided with a detecting device, which is a photoelectric sensor, and a light shielding strip is arranged on the solvent dissolver, and the photoelectric sensor is used together with the light shielding tape to detect whether the solvent dissolver has been installed to the designated position. When the detecting device detects that the solvent dissolver is not installed on the handle, the first electromagnetic valve is opened, the purifying pump works, the front end of the handle keeps the small power clean air blowing, and the front end of the handle is replaced with a clean and sterile environment to prevent the bacteria from being dissolved. Drugs, drugs cause pollution. When it is detected that the dissolver has been mounted on the handle, the first solenoid valve is opened and the purge pump is stopped.
上述安装工作完成后，开始无菌配药***的配药工作，来自主工作泵的空气作为溶药器中胶塞运动的动力。实际操作中，操作人员手持手柄，并通过手柄上的相关按键控制操作。手柄上设有“前进”和“后退”两个按键，其分别用来控制第二电磁阀73和第三电磁阀74的通断。当按下“前进”按键时，第二电磁阀73打开，空气沿中效过滤器31、B1、B2、进气口、出气口、A2、A3、C2、C3流动，空气从气源输出装置输出后，经由手柄及手柄内的高效过滤器，注入溶药器，推动胶塞前行，将溶药器中的药液推送出去，此时胶塞前端为洁净无菌空气，后端也为无菌空气；当按下“后退”按键时，第三电磁阀74打开，空气从气源输出装置的外部吸入，经由手柄及手柄内的高效过滤器进入气源输出装置，并沿C3、C2、B3、B2、进气口、出气口、A2、A1流动。此时，在溶药器的尾部形成一个负压区，吸引胶塞退回，能够将药瓶中的药液抽进溶药器。这样重复几次使用“前进”“后退”按键，使活塞反复运动，直到药液溶合完成。After the above installation work is completed, the dispensing operation of the aseptic dispensing system is started, and the air from the main working pump is used as the driving force for the rubber stopper movement in the dissolver. In actual operation, the operator holds the handle and controls the operation through the relevant buttons on the handle. The handle is provided with two buttons of "forward" and "reverse" for controlling the on and off of the second solenoid valve 73 and the third solenoid valve 74, respectively. When the "forward" button is pressed, the second solenoid valve 73 is opened, and the air flows along the intermediate effect filter 31, B1, B2, the air inlet, the air outlet, A2, A3, C2, C3, and the air is output from the air source. After the output, the drug dissolver is injected through the handle and the high-efficiency filter in the handle to push the rubber plug forward, and the liquid medicine in the solvent dissolver is pushed out. At this time, the front end of the rubber plug is clean and sterile air, and the back end is also Aseptic air; when the "back" button is pressed, the third solenoid valve 74 is opened, air is drawn in from the outside of the air source output device, and enters the air source output device via the handle and the high efficiency filter in the handle, and along the C3, C2 , B3, B2, air inlet, air outlet, A2, A1 flow. At this time, a negative pressure zone is formed at the tail of the solvent dissolver, and the rubber stopper is sucked back, and the liquid medicine in the medicine bottle can be drawn into the solvent dissolver. Repeat the use of the "Forward" and "Back" buttons several times to make the piston move repeatedly until the solution is dissolved.
无菌配药***通过气源输出装置，以及高效过滤器对手柄前端空气的置换作用，能够保证在整个配药过程中，溶药器的腔体中始终保持无菌环境，极大的保证用患者的用药安全。The aseptic dispensing system through the gas source output device, as well as the high-efficiency filter to replace the air at the front end of the handle, can ensure that the cavity of the solvent dissolver always maintains a sterile environment throughout the dispensing process, greatly ensuring the patient's Medication safety.
实施例十六Example sixteen
本实施例与上述实施例的不同之处在于：净化子装置为第四电磁阀，其设置在主工作泵的输气管道上，用来控制主工作泵输出小气流的洁净空气。第四电磁阀与第二电磁阀的区别在于，第四电磁阀具有更高的精度，能控制小流量的气流。The difference between the embodiment and the above embodiment is that the purifying sub-device is a fourth electromagnetic valve disposed on the gas pipeline of the main working pump for controlling the clean air of the small working airflow output by the main working pump. The fourth solenoid valve differs from the second solenoid valve in that the fourth solenoid valve has higher precision and can control a small flow of air.
如图23所示，其为本实施例气体流通示意图。主工作泵79一直处于工作状态， 当第四电磁阀打开，第二电磁阀、第三电磁阀关闭时，空气沿中效过滤器31，B1，B2，进气口，出气口，D1，D2流动，空气经由三通，最终从输出口76输出，输出的空气为平稳、缓和的小流量洁净空气；当第二电磁阀打开时，空气沿中效过滤器31、B1、B2、进气口、出气口、A2、A3、C2、C3流动，最终从输出口76输出，输出的为大流量洁净空气，可作为一种动力源；当第三电磁阀74打开时，空气从输出口76输入，沿C3、C2、B3、B2、进气口、出气口、A2、A1流动，将空气抽进气源输出装置。As shown in Fig. 23, it is a schematic diagram of the gas flow of the present embodiment. The main working pump 79 is always in operation. When the fourth solenoid valve is opened, the second solenoid valve and the third solenoid valve are closed, the air flows along the intermediate effect filter 31, B1, B2, the air inlet, the air outlet, D1, D2, and the air passes through the tee, and finally The output port 76 outputs, the output air is a smooth and gentle small flow clean air; when the second electromagnetic valve is opened, the air along the intermediate effect filter 31, B1, B2, air inlet, air outlet, A2, A3, C2 C3 flows, and finally outputs from the output port 76. The output is a large flow of clean air, which can be used as a power source; when the third solenoid valve 74 is opened, air is input from the output port 76 along C3, C2, B3, and B2. The air inlet, the air outlet, the A2 and the A1 flow, and the air is pumped to the air source output device.
实施例十七Example seventeen
本实施例与上述实施例不同之处在于：净化子装置为一储气瓶，其内部装有洁净的空气，通过储气瓶的开关控制小气流洁净空气的输出。净化装置选用储气瓶具有价格低，使用方便的特点，但另一方面，储气瓶本身没有自我净化的功能，所以需要定时更换新的储气瓶，以保证气源输出装置输出的为洁净的空气。The difference between the embodiment and the above embodiment is that the purifying device is a gas cylinder, and the inside is filled with clean air, and the output of the small air purifying air is controlled by the switch of the gas cylinder. The purifying device uses a gas cylinder with low price and convenient use. On the other hand, the gas cylinder itself does not have the function of self-purification, so it is necessary to replace the new gas cylinder regularly to ensure that the output of the gas source output device is clean. air.
如图24所示，其为本实施例气体流通示意图。当储气瓶开关打开时，储气瓶内部的洁净空气经由三通，最终由输出口76输出，输出的空气为平稳、缓和的小流量洁净空气；主工作泵79一直处于工作状态，当第二电磁阀打开时，空气沿中效过滤器31、B1、B2、进气口、出气口、A2、A3、C2、C3流动，最终从输出口76输出，输出的为大流量洁净空气，可作为一种动力源；当第三电磁阀74打开时，空气从输出口76输入，沿C3、C2、B3、B2、进气口、出气口、A2、A1流动，将空气抽进气源输出装置。As shown in Fig. 24, it is a schematic diagram of gas flow in the present embodiment. When the gas cylinder switch is turned on, the clean air inside the gas cylinder is passed through the tee, and finally outputted by the output port 76, and the output air is a smooth and gentle small flow clean air; the main working pump 79 is always in working state, when the first When the two solenoid valves are opened, the air flows along the intermediate effect filters 31, B1, B2, the air inlets, the air outlets, A2, A3, C2, and C3, and finally outputs from the output port 76, and the output is a large flow of clean air. As a power source; when the third solenoid valve 74 is opened, air is input from the output port 76, flows along C3, C2, B3, B2, the air inlet, the air outlet, A2, A1, and the air is drawn to the air source. Device.
实施例十八Example 18
本实施例与上述实施例不同之处在于：净化子装置为一储气瓶，其内部的气体来自于主工作泵79，储气瓶内部设有压力控制单元，用来检测并平衡储气瓶内部的气压。当储气瓶的开关打开，储气瓶通过三通向外排气时，压力控制单元控制储气瓶从上部箱体抽气；储气瓶的开关关闭时，储气瓶也停止向内抽气，以维持储气瓶内部的气压平衡。本实施例提供的技术方案，不用定期对储气瓶进行更换，又设有压力控制单元，具有方便、高效的优点。The difference between the embodiment and the above embodiment is that the purifying device is a gas cylinder, the gas inside is from the main working pump 79, and the gas cylinder is internally provided with a pressure control unit for detecting and balancing the gas cylinder. Internal air pressure. When the gas cylinder switch is opened and the gas cylinder is exhausted through the tee, the pressure control unit controls the gas cylinder to pump from the upper tank; when the gas cylinder switch is closed, the gas cylinder also stops pumping inward. Gas to maintain the air pressure balance inside the cylinder. The technical solution provided by the embodiment does not need to replace the gas cylinder regularly, and is provided with a pressure control unit, which has the advantages of convenience and high efficiency.
如图25所示，其为本实施例气体流通示意图。主工作泵79一直处于工作状态，当第二电磁阀73和第三电磁阀74均为关闭状态时，空气沿中效过滤器31，B1，B2，进气口，出气口，A2，A1流动，将空气排放到上部箱体中。当储气瓶的开关打开时，瓶内的空气经由三通，最后从输出口76输出，输出的空气为平稳、缓和的小流量洁净空气，同时储气瓶在压力控制单元的作用下从上部箱体内抽气，以维持储气瓶内部的气压平衡。当第二电磁阀打开时，空气沿中效过滤器31、B1、B2、进气口、出气口、A2、A3、C2、C3流动，最终从输出口76输出，输出的为大流量洁净空气，可作为一种动力源；当第三电磁阀74打开时，空气从输出口76输入，沿C3、C2、B3、B2、进气口、出气口、A2、A1流动，将空气抽进气源输出装置，过滤后运送到上部箱体内，并在需要的时候进行排出。主工作泵79和净化子装置，作为两种不同的气源输出端，可提供小流量、平稳的洁净空气，又可提供大流量、可作为动力源的洁净空气，使用者可根据实际需要对其进行选择，具有很强的实用性。另外，换新时可单独更换，使用起来方便有效，又不至于成本太高。As shown in Fig. 25, it is a schematic diagram of the gas flow of the present embodiment. The main working pump 79 is always in the working state. When the second electromagnetic valve 73 and the third electromagnetic valve 74 are both closed, the air flows along the intermediate effect filter 31, B1, B2, the air inlet, the air outlet, A2, A1. , the air is discharged into the upper tank. When the switch of the gas cylinder is opened, the air in the bottle passes through the tee, and finally is outputted from the output port 76, and the output air is a smooth, gentle, small-flow clean air, and the gas cylinder is operated from the upper part by the pressure control unit. The tank is pumped to maintain the air pressure balance inside the cylinder. When the second solenoid valve is opened, the air flows along the intermediate effect filter 31, B1, B2, the air inlet, the air outlet, A2, A3, C2, C3, and finally outputs from the output port 76, and the output is a large flow of clean air. It can be used as a power source; when the third solenoid valve 74 is opened, air is input from the output port 76, and flows along the C3, C2, B3, B2, the air inlet, the air outlet, the A2, and the A1, and the air is taken in. The source output device is filtered, transported to the upper tank, and discharged as needed. The main working pump 79 and the purifying sub-device, as two different gas source output terminals, can provide a small flow, smooth clean air, and can provide a large flow, clean air that can be used as a power source, and the user can It is very practical for its selection. In addition, it can be replaced separately when it is renewed, it is convenient and effective to use, and it is not too expensive.
实施例十九Example 19
本实施例与上述实施例不同之处在于：如图26所示，支撑结构为支撑板262，其上端与下端设有凸起，下部箱体底部、隔热层与支撑板的连接处设有凹槽，连接时，凸起陷在凹槽中。支撑板为可拆卸结构，便于更换，方便实用。支撑板上设有镂空和加强筋，镂空的设计除了节省原材料外，更重要的是具有良好的散热效果，加强筋可有效增加支撑架的强度和刚性，避免受力不均造成支撑架歪扭变形，以此提高设备的整体稳定性。The embodiment is different from the above embodiment in that, as shown in FIG. 26, the support structure is a support plate 262, and the upper end and the lower end are provided with protrusions, and the bottom of the lower box body and the connection between the heat insulation layer and the support plate are provided. The groove, when connected, the protrusion is trapped in the groove. The support plate is detachable structure, easy to replace, convenient and practical. The support plate is provided with hollowing and reinforcing ribs. In addition to saving raw materials, the hollow design has a good heat dissipation effect. The reinforcing ribs can effectively increase the strength and rigidity of the support frame, and avoid the uneven force caused by the support frame. Deformation to improve the overall stability of the device.
支撑板的材质最好为钣金，因为其具有较好的刚度，不易折断、变形，能起到很好的支撑作用。另外，钣金材质的支撑板能有效抵御气泵、继电器等设备工作产生的震动，大大提高气源输出装置的整体稳固性。The material of the support plate is preferably sheet metal, because it has good rigidity, is not easy to be broken and deformed, and can play a good supporting role. In addition, the support plate of sheet metal can effectively resist the vibration generated by the operation of air pump, relay and other equipment, and greatly improve the overall stability of the air source output device.
实施例二十 Example twenty
本实施例与上述实施例不同之处在于：如图27所示，其为本实施例的结构示意图。隔热层与下部箱体间的支撑结构为：在隔热层的四个顶点处设立四个立柱，立柱上端与隔热层螺纹连接，下端与下部箱体底部螺纹连接。每两个相邻的立柱间焊接有加强筋，其起到加固的作用。加强筋为不锈钢材料制成，其具有耐蒸汽、水等弱腐蚀介质的特点，有效抵御各设备工作时产生的高温水蒸气，不锈钢材质不易损坏，可长期使用，具有较高的性价比。加强筋的位置不限于图25所示的对角线处，还可设置在顶角处等需要加固的地方。The difference between this embodiment and the above embodiment is as shown in FIG. 27, which is a schematic structural view of the embodiment. The supporting structure between the heat insulating layer and the lower box body is: four columns are set at four vertices of the heat insulating layer, the upper end of the column is screwed with the heat insulating layer, and the lower end is screwed with the bottom of the lower box body. A reinforcing rib is welded between each two adjacent columns, which serves as a reinforcement. The rib is made of stainless steel material, which has the characteristics of resistance to weak corrosive medium such as steam and water. It is effective against the high temperature steam generated by the working of various equipments. The stainless steel material is not easy to be damaged, and can be used for a long time, and has high cost performance. The position of the rib is not limited to the diagonal line shown in Fig. 25, and may be provided at a corner and the like where reinforcement is required.
实施例二十一 Embodiment 21
本实施例与上述实施例不同之处在于：与开关71配合使用的触发装置81为：用单片机驱动三极管的装置，来自开关的小电流作为三极管的基极输入电流，基于三极管的共发射极放大电路基本原理，最终从集电极输出放大电流，供气源输出装置各设备使用。本实施例提供的技术方案具有耗电低，速度快，寿命长的优点。The difference between this embodiment and the above embodiment is that the trigger device 81 used in conjunction with the switch 71 is a device for driving a triode with a single chip, and a small current from the switch is used as a base input current of the triode, and the common emitter is amplified based on the triode. The basic principle of the circuit, the final output of the amplified current from the collector, used by the gas source output device. The technical solution provided by this embodiment has the advantages of low power consumption, high speed, and long service life.
以上所述仅为本发明的较佳实施例，对本发明而言仅仅是说明性的，而非限制性的。本专业技术人员理解，在本发明权利要求所限定的精神和范围内可对其进行许多改变，修改，甚至等效，但都将落入本发明的保护范围内。 The above are only the preferred embodiments of the present invention, and are merely illustrative and not restrictive. It will be understood by those skilled in the art that many changes, modifications, and equivalents may be made within the spirit and scope of the invention as defined by the appended claims.

Claims (10)

  1. 一种无菌配药***，其特征在于，其包括：An aseptic dispensing system characterized in that it comprises:
    溶药单元，用于提供混合药剂的腔体；a drug dissolution unit for providing a cavity for mixing the medicament;
    动力单元，用于为所述溶药单元提供动力。A power unit for powering the solvent unit.
  2. 如权利要求1所述的无菌配药***，其特征在于，所述无菌配药***还包括第一手持部件和除菌单元，所述手持部件与所述动力单元可拆卸地连接，所述除菌单元用于滤除空气中的杂质和细菌。The sterile dispensing system of claim 1 wherein said aseptic dispensing system further comprises a first hand held component and a sterilization unit, said hand held component being detachably coupled to said power unit, said removing The bacteria unit is used to filter out impurities and bacteria in the air.
  3. 如权利要求2所述的无菌配药***，其特征在于，所述动力单元包括一管路组和第一气泵，所述第一气泵与所述管路组连通，所述管路组至少包括四个管路，所述管路组包括电磁阀组，所述电磁阀组至少包括四个电磁阀，所述电磁阀组中电磁阀的数量与所述管路组中管路数量相对应。The aseptic dispensing system of claim 2 wherein said power unit comprises a tubing set and a first air pump, said first air pump being in communication with said tubing set, said tubing set comprising at least Four pipelines, the pipeline group includes a solenoid valve group, the solenoid valve group includes at least four solenoid valves, and the number of solenoid valves in the solenoid valve group corresponds to the number of pipelines in the pipeline group.
  4. 如权利要求1所述的无菌配药***，其特征在于，所述无菌配药***还包括无菌单元，其用于构筑一无菌环境，所述无菌单元包括一配药推杆和一套杆，所述配药推杆位于所述套杆内，且所述配药推杆与所述套杆可相对运动，所述溶药单元与所述无菌单元为密封连接；所述动力单元为一致动部，其用于带动所述配药推杆前进或后退。The aseptic dispensing system of claim 1 wherein said aseptic dispensing system further comprises a sterile unit for constructing a sterile environment, said sterile unit comprising a dispensing pusher and a set a rod, the dispensing push rod is located in the sleeve rod, and the dispensing push rod and the sleeve rod are relatively movable, and the solvent-dissolving unit is in sealing connection with the aseptic unit; the power unit is consistent a moving portion for driving the dispensing pusher to advance or retreat.
  5. 如权利要求4所述的无菌配药***，其特征在于，所述无菌配药***还包括第一洁净层流装置、净化装置和第二气泵，所述净化装置一端与所述第一洁净层流装置连通，另一端与所述第二气泵连通。The aseptic dispensing system of claim 4, wherein the aseptic dispensing system further comprises a first clean laminar flow device, a purification device, and a second air pump, the purification device having one end and the first clean layer The flow device is in communication and the other end is in communication with the second air pump.
  6. 如权利要求1所述的无菌配药***，其特征在于，所述无菌配药***还包括第二手持部件、除菌装置、第二洁净层流装置、第一磁体和第二磁体；活塞内置于所述溶药单元，所述胶塞内设有第一磁体；所述第二手持部件一端与所述溶药单元可拆卸地连接，另一端与所述动力单元连通，所述第二手持部件内部设有第二磁体；所述第二洁净层流装置与所述动力单元连通，所述除菌装置与所述动力单元连通。The aseptic dispensing system of claim 1 wherein said aseptic dispensing system further comprises a second hand held component, a sterilization device, a second clean laminar flow device, a first magnet and a second magnet; a piston Built in the solvent-dissolving unit, the rubber plug is provided with a first magnet; one end of the second hand-held component is detachably connected to the solvent-dissolving unit, and the other end is connected to the power unit, the first A second magnet is disposed inside the two hand-held components; the second clean laminar flow device is in communication with the power unit, and the sterilization device is in communication with the power unit.
  7. 如权利要求6所述的无菌配药***，其特征在于，所述除菌装置包括第一除菌装置和第二除菌装置，所述第一除菌装置设置在所述第二手持部件内部，所述第二洁净层流装置通过所述第二除菌装置与所述气动单 元连通，所述第二磁体为电磁铁。The aseptic dispensing system according to claim 6, wherein said sterilization device comprises a first sterilization device and a second sterilization device, said first sterilization device being disposed on said second hand held component Internally, the second clean laminar flow device passes through the second sterilization device and the pneumatic single The element is connected, and the second magnet is an electromagnet.
  8. 如权利要求1所述的无菌配药***，其特征在于，所述无菌配药***还包括第一净化装置、第二净化装置和第三洁净层流装置，所述第一净化装置一端与所述溶药单元连接；所述第二净化装置一端与所述第三洁净层流装置连通，另一端与所述动力单元连通，活塞内置于所述溶药器本体，所述活塞内部设有第三磁体，所述第一净化装置内部设有第四磁体。The aseptic dispensing system of claim 1 wherein said aseptic dispensing system further comprises a first purification device, a second purification device, and a third clean laminar flow device, said first purification device having one end The solvent-dissolving unit is connected; one end of the second purifying device is in communication with the third clean laminar flow device, and the other end is in communication with the power unit, the piston is built in the solvent body, and the piston is internally provided with A three-magnet, the first purification device is internally provided with a fourth magnet.
  9. 如权利要求1所述的无菌配药***，其特征在于，所述无菌配药***还包括第一净化装置、第二净化装置和第四洁净层流装置，所述动力单元包括第三气泵和第四气泵，所述第一净化装置一端与所述溶药单元连接，另一端与所述第三气泵连通；所述第二净化装置一端与所述第四洁净层流装置连通，另一端与所述第四气泵连通，活塞内置于所述溶药器本体。The aseptic dispensing system of claim 1 wherein said aseptic dispensing system further comprises a first purification device, a second purification device, and a fourth clean laminar flow device, said power unit comprising a third air pump and a fourth air pump, one end of the first purifying device is connected to the solvent-dissolving unit, and the other end is connected to the third air pump; one end of the second purifying device is connected to the fourth clean laminar flow device, and the other end is connected The fourth air pump is in communication, and the piston is built in the solvent body.
  10. 如权利要求1所述的无菌配药***，其特征在于，所述动力单元为一种气源输出装置，其包括：The aseptic dispensing system of claim 1 wherein said power unit is a gas source output device comprising:
    主工作泵，其用来输出大流量洁净空气；Main working pump for outputting large flow of clean air;
    净化子装置，其用来输出缓和的小流量洁净空气。 A purifying device for outputting a gentle, small flow of clean air.
PCT/CN2017/000362 2016-05-18 2017-05-18 Aseptic medication preparation system WO2017197907A1 (en)

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
CN201610329493.2 2016-05-18
CN201610329493.2A CN105796340B (en) 2016-05-18 2016-05-18 A kind of sterile dispensing system
CN201620781461.1 2016-07-22
CN201620781399.6 2016-07-22
CN201620781461.1U CN206273281U (en) 2016-07-22 2016-07-22 A kind of sterile dispensing system
CN201620781400.5 2016-07-22
CN201620781398.1U CN206261831U (en) 2016-07-22 2016-07-22 A kind of sterile dispensing system
CN201620781400.5U CN206275831U (en) 2016-07-22 2016-07-22 A kind of sterile dispensing system
CN201620781399.6U CN206261832U (en) 2016-07-22 2016-07-22 A kind of sterile dispensing system
CN201620781398.1 2016-07-22
CN201720052251.3 2017-01-17
CN201720052251.3U CN208710520U (en) 2017-01-17 2017-01-17 A kind of gas source output device and the sterile dispensing system with the device

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