WO2017162120A1 - 溶配药器 - Google Patents
溶配药器 Download PDFInfo
- Publication number
- WO2017162120A1 WO2017162120A1 PCT/CN2017/077311 CN2017077311W WO2017162120A1 WO 2017162120 A1 WO2017162120 A1 WO 2017162120A1 CN 2017077311 W CN2017077311 W CN 2017077311W WO 2017162120 A1 WO2017162120 A1 WO 2017162120A1
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- WIPO (PCT)
- Prior art keywords
- puncturing
- base
- frame
- solvent
- bases
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2006—Piercing means
- A61J1/2017—Piercing means having three or more piercing ends
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
Definitions
- the embodiments of the present application relate to, but are not limited to, the field of infusion dispensing devices, and in particular to a solvent dispenser for automatically dissolving drugs.
- the existing infusion-dissolving drugs are basically dispensed by using syringes and other simple forms. In the process of dispensing, they cannot be continuously prepared, and the efficiency is low, the speed is slow, and the labor intensity is large; when the packaging of the vials is packaged, due to multiple punctures of Xilin
- the rubber stopper of the bottle and the infusion container is easy to cause leakage and particulate contamination; in the preparation of cytotoxic drugs, chemotherapeutic drugs, sensitizing drugs, high activity and other drugs, the rubber plugs of the vials and infusion containers are easily punctured, which is easy to produce.
- Drug spillage and volatilization may bring irreversible consequences; multiple puncture of the stopper of the vial and infusion container, due to the exposure of the needle to a non-sterile environment, microorganisms may contaminate the needle, contaminated microorganisms may It will cause secondary contamination of infusion microbes with multiple punctures; manual operation is easily affected by the operator's mental state and dispensing speed requirements.
- the state requires the establishment of a medical institution's dispensing center, which requires innovation in dispensing methods, to the point of automation, high efficiency, A non-polluting dispensing method appears.
- the existing disposable infusion equipment and the disposable solvent dispensing device are exposed to the puncture device, and are easily stabbed when the medicine is manually dispensed, and the dispensing speed is slow, which is not suitable for automatic preparation, multiple punctures during the operation, and non-fully closed preparation.
- Freeze-dried powder injection Xilin bottle
- Xilin bottle can produce micro-vacuum in the production process.
- the operator needs to repeat the puncture.
- the internal pressure is balanced to extract the liquid.
- the embodiments of the present application provide a solvent dispenser.
- the solvent dispenser provided by the embodiment of the present application is used for automatically dissolving a drug, comprising:
- each of the first puncturing devices is provided with a through inner passage, and the top end has a sharp puncturing portion, and the two first puncturing devices are mounted on the puncturing base The other two of the first puncturing devices are mounted on the other puncturing base;
- Two first elastic infusion hoses two ends of one of the first elastic infusion hoses respectively and a bottom end of an inner passage of two of the first piercers mounted on the bases of the two piercers Connected to each other, the two ends of the other first elastic infusion hose are respectively connected to the bottom ends of the inner passages of the other two first punctors mounted on the two puncturing bases;
- two of the first piercers on the base of the piercer are configured to pierce a drug container and communicate with the drug container;
- Two of the first piercers on the base of the device are configured to pierce another drug container in communication with the other drug container;
- two of the first elastic infusion hoses are configured to be in each of the Each of the first elastic infusion hoses is provided with a peristaltic pump, and the two peristaltic pumps work to squeeze two of the first elastic infusion hoses, so that the contents of the two containers are flowed and mixed with each other. Dissolving the drug.
- At least one of the two piercing bases is movably mounted within the frame, each of the first flexible infusion hoses having a length greater than between the two piercing bases The distance does not limit the movement of the frame;
- the first puncturing device on the movable trocar base is stored in the frame before use of the solvent dispenser; the puncturing movable when the solvent dispenser is in use The base is moved such that the first piercer thereon extends out of the frame.
- two of the piercer bases are movably mounted within the frame.
- the frame is provided with a needle guide corresponding to the movable trocar base a hole, the pin guide hole is a through hole penetrating a wall of the frame;
- the solvent dispenser When the solvent dispenser is in use, it moves through the needle guide hole and along the needle guide hole to move the piercer base.
- the length of the dial guide hole is set such that the movable piercer base is movable to a movable upper surface of the piercer base that is flush with the upper surface of the frame.
- a movable needle piercing base is provided with a pin punching hole.
- the movable piercer base is moved along the needle guide hole by the needle punching.
- one of the inner side wall of the frame and the outer side wall of the moving puncturing device base is provided with a guide rail, and the other is provided with a sliding slot, and the guiding rail cooperates with the sliding slot and can be opposite Moving in the chute.
- a pedestal guide well is disposed on both sides of the frame, and a guide rail is disposed on an inner sidewall of each pedestal guide well;
- Two of the puncturing bases are respectively located in the pedestal guide wells on both sides, and are provided with a sliding groove that cooperates with the guide rail.
- At least one of the two piercing bases is fixedly mounted within the frame
- the medicated container corresponding to the fixed puncturing pedestal is moved to be pierced by the first puncturing device on which the fixed puncturing pedestal is moved.
- the lengths of the two first puncturing devices on at least one of the two puncturing device bases are the same or different.
- the lengths of the two first puncturing devices on each of the puncturing device bases are different;
- the length of the portion of the trocar base is 8-10 mm, and the length of the portion of the puncturing device that exposes the puncturing base is not longer than 28 mm.
- the middle portion of the lower end of the frame is provided with an arc-shaped recessed portion, and the two sides of the recessed portion are respectively provided with two through holes for the two first elastic infusion hoses to pass through. ;
- the shape of the recess is configured to match the curvature of the rotation of the rollers of the two peristaltic pumps.
- a buckle is disposed on an outer wall surface of the frame, and the buckle is configured to be engaged with the card seat.
- the solvent dispenser further comprises:
- At least one second elastic infusion hose At least one second elastic infusion hose
- each pair of second puncturing devices comprising two second puncturing devices, and the structure of the second puncturing device is the same as that of the first puncturing device;
- one of said second puncturing devices is mounted on a base of said trocar, and the other of said second puncturing devices is mounted on a base of said other puncturing device, and Two of the second puncturing devices are respectively connected to two ends of one of the second elastic infusion hoses;
- At least one of the second elastic infusion hoses is configured to be provided with a peristaltic pump at each of the second elastic infusion hoses.
- the embodiment of the present application further provides a disposable vial solvent dispenser for an automatic solvent dispensing system, comprising four puncture devices, two elastic infusion hoses, two puncture bases and a frame.
- the puncturing device is hollow and forms an inner passage, and the top end of the puncturing device is open to communicate with the inner passage and is made sharp, and the bottom end is also open to communicate with the inner passage.
- each elastic infusion hose Two ends of each elastic infusion hose are respectively connected with the bottom end of one puncturing device to form one channel, and two of the channels are parallel; two puncturing devices at each end of the two channels are fixed on a puncturing base ;
- the frame is arched and has pedestal guide wells at both ends.
- the two puncturing bases are respectively placed in the pedestal guide wells at both ends of the frame;
- the middle and lower parts of the frame have arc-shaped areas, called arches, and the shape of the arches.
- the rotations of the rollers of the two peristaltic pumps are matched, and the two inner side walls of the arches respectively penetrate two parallel holes communicating with the adjacent pedestal guide wells, and two elastic infusion hoses pass through the holes and Connected to the puncturing device on the trocar base of the pedestal guide well at both ends, and the elastic infusion hose is fixed in the tunnel;
- the two trocar bases are located at the bottom of the pedestal guide well, and the four puncturing devices are housed in the pedestal guide well;
- the trocar base is configured to be outwardly slid along the pedestal well through the needle device in the automatic solvent dispensing system, and the elastic infusion hose is dragged to follow the puncturing base motion, puncture The device is then removed from the pedestal guide well.
- two puncturing devices at one end are configured to be inserted into the infusion container, and two puncturing devices at the other end are configured to be inserted into the vial; and two elastic infusion hoses are configured.
- two elastic infusion hoses are respectively clamped and fixed between the inner top wall of the arch and the corresponding peristaltic pump roller to be crushed by the roller.
- the flow of fluid in the flexible infusion hose is driven by the power of the peristaltic pump to perform the corresponding dissolving operation.
- the four puncturing devices are made of medical stainless steel or medical plastic.
- the two elastic infusion hoses are made of medical plastic material.
- the two trocars on each puncturing base comprise a short puncturing device and a long puncturing device, and the short puncturing device exposes the pedestal base portion to a length of 8-10 mm, and the long puncturing device exposes the puncturing device base
- the length of the part is not longer than 28 mm; or the two puncturing devices on the base of each puncturing device are equal length puncturing devices;
- the piercing device base has a pin perforation, the pin perforation is configured to be inserted by the dialing device of the automatic solvent dispensing system to dial the piercer base; and the piercer base is provided with one or more slides The slot is intended to be guided when it is toggled.
- one or more guide rails are provided in the pedestal guide well for the puncturing base
- the chute fits to guide the movement of the puncturing base
- Two pedestal guide wells are provided with equal length guide holes on both sides, and the length of the directional guide holes is set such that the upper surface of the puncturing base and the upper surface of the frame are removed after the puncturing device base is removed Reach the same plane;
- the openings of the four holes on the inner side walls of the arch are all at the same level, and the axis line of one hole on one inner side wall of the arch is in line with the axis line of the corresponding hole on the other inner side wall of the arch.
- the axis line of the other hole on one inner side wall of the arch is on the same straight line as the axis line of the corresponding hole on the other inner side wall of the arch, and the two straight lines are parallel to each other.
- the disposable vial solvent dispenser is locked on the card holder of the automatic solvent dispensing system, and the elastic infusion hose can be clamped and fixed between the top wall of the frame arch and the roller of the peristaltic pump, and then the needle is inserted.
- the device passes through the guide hole of the needle, and then penetrates into the through hole of the needle, and the two piercer bases are moved outward along the base guide well, and the puncturing device on the base of the two puncturing devices simultaneously or separately penetrates the infusion
- the container and the vial are formed to form a two-channel internal communication closure system.
- the two-way two-way fluid delivery is provided during the solvent dispensing process by the controllable two-way driving of the two peristaltic pumps, and the fluid is formed between the infusion container, the vial and the two channels as needed during the dissolution of the drug.
- Different flow modes form intense turbulence in the vial, so that the drug in the vial can be quickly dissolved, and the pressure in the vial and the infusion container can be balanced to quickly dissolve the drug solution into the infusion container; the drug in the vial After completely dissolving and transferring to the infusion container, the two puncture pedestals are simultaneously or separately dialed back to the bottom of the pedestal guide well through the needle setting device, and the puncturing devices on the two pedestals are from the infusion container and the vial Pull out and complete the drug dissolution operation.
- the solvent-dispensing device provided by the embodiment of the present invention does not need to repeatedly insert and withdraw the puncturing device in the process of dissolving the drug, and can realize the fully-closed solvent-dissolving process, which not only reduces the labor intensity of the dispensing, but also realizes continuous preparation and improves efficiency; In addition, it avoids the damage caused by liquid leakage and leakage to the dispensing personnel; at the same time, it reduces or avoids the pollution of particles and the secondary pollution of microorganisms.
- Embodiments of the present application enable automated, highly efficient, non-polluting dispensing.
- FIG. 1 is a schematic structural view of a solvent dispenser in an unused state according to an embodiment of the present application
- FIG. 2 is a schematic structural view showing a state of use of a solvent dispenser according to an embodiment of the present application
- FIG. 3 is a schematic perspective structural view showing the unused state of the solvent dispenser of the embodiment of the present application.
- FIG. 4 is a schematic structural view showing the unused state of the solvent dispenser of the embodiment of the present application after the frame is omitted;
- FIG. 5 is a schematic structural view showing a state in which the solvent-dissolving device of the embodiment of the present application is used after the frame is omitted;
- FIG. 6 is a schematic structural view of a frame of a solvent dispenser according to an embodiment of the present application.
- Fig. 7 is a schematic view showing the structure of a solvent dispenser of the embodiment of the present application for an automatic solvent dispensing system.
- Embodiment 1 is a diagrammatic representation of Embodiment 1:
- the sirrel bottle dissolving device is composed of four puncturing devices 28-31, two elastic infusion hoses 2-3, two puncturing device bases 14-15 and a frame 1.
- the puncturing device 28-31 is hollow, forming an inner channel, and the apex 28-31 has a top end opening, and can be made sharp and communicates with the inner channel, and the bottom end also has an opening and an inner channel. Connected.
- the two ends of the elastic infusion hose 2 are respectively connected with the bottom ends of the puncturing devices 29, 30, and the composition can be defined as a channel, and the elastic infusion hose 2 of the channel can be fixed to an external peristaltic pump of the automatic solvent dispensing system. 39, powered by the peristaltic pump 39, driving the fluid (such as liquid, gas, liquid-solid mixture) in the elastic infusion hose 2; the two ends of the elastic infusion hose 3 and the bottom of the piercers 28, 31, respectively The end phase is connected, and the component structure can be defined as a channel.
- the fluid such as liquid, gas, liquid-solid mixture
- the elastic infusion hose 3 of the channel can be fixed on an external peristaltic pump 38 of the automatic solvent dispensing system, and powered by the peristaltic pump 38 to drive the elastic infusion hose 3
- the fluid eg, liquid, gas, liquid-solid mixture
- reference numerals 24-27 are the junctions of the flexible infusion hoses 2, 3 and the trocars 28-31.
- the two channels of the solvent dispenser are parallel, and the two puncturing devices 28, 29 and 30, 31 at each end are respectively fixed to a puncturing device base 14, 15 and in a parallel state.
- the frame 1 is in the shape of an arch bridge, and the two ends are the base guide wells 22, 23.
- the two piercer bases 14, 15 are respectively placed in the base guide wells 22, 23 at the two ends of the frame 1, And it is slidable relative to the base channel wells 22, 23.
- the piercer bases 14, 15 are located at the bottom of the base channel wells 22, 23, at which point the piercers 28-31 are housed in the base channel wells. 22, 23; when the drug dispensing device is used, the needle device (not shown) in the automatic solvent dispensing system pushes the piercer bases 14, 15 outward along the base channel wells 22, 23, respectively, and dials
- the flexible infusion hoses 2, 3 connected to the trocar bases 14, 15 can be dragged to follow the trocar bases 14, 15, the puncturing devices 28-31 are then withdrawn from the pedestal guide wells 22, 23 The top end of the puncturing device 28-31 is extended (as shown in FIGS.
- the puncturing devices 28, 29 having one end connected in parallel can be inserted into the infusion container 36, and the other end is connected in parallel.
- the puncturing device 30, 31 can be inserted Inside the vial 37. Thus, a passage through which fluid flows is formed between the infusion container 36 and the vial 37.
- the lengths of the two elastic infusion hoses 2, 3 are greater than the distance between the two puncture bases 14, 15. Therefore, when not in use, the two elastic infusion hoses 2, 3 are in an untensioned state, such as two elastic infusion hoses 2, 3 can be coiled to save space.
- the arcuate region of the lower portion of the frame 1 is referred to as an arch 44, and its arched design is primarily designed to match the curvature of the rollers of the two peristaltic pumps 38, 39 in the automelt dispensing system.
- the two inner sidewalls of the arch 44 extend through two parallel bores 40-43, respectively, and the parallel bores 40, 41 communicate with adjacent pedestal guide wells 23, and the parallel bores 42, 43 communicate with adjacent pedestal guide wells 22. .
- the two ends of the two elastic infusion hoses 2, 3 are respectively passed through the holes 40-43 on the inner side walls of the arch 44 and are fixed to the puncturing bases 14 and 15 in the pedestal guide wells 22, 23 on both sides.
- the upper puncturing device 28-31 is connected, and the elastic infusion hoses 2, 3 can be fixed in the tunnels 40-43.
- the four parallel holes 40-43 on the inner side walls of the arch 44 are at the same level, and the axis line of one of the holes 42 on the inner side wall of the arch 44 and the corresponding hole 40 on the other inner side wall of the arch 44
- the axis lines are on the same straight line, and the axis line of the other hole 42 on one inner side wall of the arch 44 is on the same straight line as the axis line of the corresponding hole 41 on the other inner side wall of the arch 44, as described above.
- the two lines are parallel to each other.
- the two elastic infusion hoses 2, 3 located in the arch 44 are parallel to each other.
- the frame 1 has a buckle on both sides, the buckle on one side has a buckle guide surface 8 and a buckle plane 10 , and the buckle on the other side has a buckle guide surface 9 and a buckle plane 11 .
- the two snaps can be attached to and locked with a card holder (not shown) of the automelt dispensing system.
- the frame 1 is fixed on the deck, the two elastic infusion hoses 2, 3 of the solvent dispenser are respectively aligned with the two peristaltic pumps 39, 38.
- the two elastic infusion hoses 2, 3 are respectively clamped and fixed between the inner top wall of the arch 44 and the rollers of the corresponding peristaltic pumps 39, 38 for roller rolling, relying on the power of the peristaltic pumps 38, 39. Corresponding solvent operation.
- the elastic infusion hoses 2, 3 are flexible so that they can be returned to the roller after it has been crushed
- the original shape is such that the roller is pressed for the next time to drive the fluid flow in the elastic infusion hoses 2, 3, thereby enabling the drug in the infusion container 36 and the vial 37 to be dissolved.
- the four puncturing devices 28-31 of the solvent dispensing device are made of medical plastics such as medical stainless steel or medical PVC to meet medical standards.
- the two elastic infusion hoses 2 and 3 of the solvent dispenser are made of medical plastic materials (such as medical PVC, TPE, TPU, medical silica gel, etc.).
- the two trocars on each trocar base can be designed to have different lengths or equivalent lengths.
- the trocar base 14 has a short puncturing device 29 and a long puncturing device 28 thereon.
- the puncturing device base 15 has a short puncturing device 31 and a long puncturing device 30, wherein the short puncturing device 29 and the long puncturing device 30 are provided.
- Connected to both ends of the elastic infusion hose 2, the short piercer 31 and the long piercer 28 are connected to both ends of the elastic infusion hose 3.
- the design of the long and short puncturing device on each puncturing base is mainly to produce more turbulent turbulence in the vial under the dual-channel dynamic cooperation and promote drug dissolution.
- the length of the portion of the short puncture device 31 exposing the puncture base 15 is 8-10 mm to ensure that the liquid medicine in the vial 37 can be aspirated as much as possible; the length of the portion of the puncture device 15 that exposes the puncture base 15 Not longer than 28mm, no more than 2ml of the height of the vial 37 (usually 28mm) to prevent the cracking of the vial 37.
- Both sides of the two pedestal wells 22 are provided with equal length guide holes 4-7, and the puncturing bases 14, 15 are provided with pin piercings 12, 13.
- the needle setting device of the automatic solvent dispensing system passes through the needle guide holes 4-7 and penetrates the needle insertion holes 12, 13 of the piercer bases 14, 15 to dial the piercer bases 14, 15.
- the length of the needle guiding hole 4-7 enables the puncturing device bases 14, 15 to be disengaged, and the upper plane of the puncturing device bases 14, 15 and the upper surface of the frame 1 reach the same plane, the puncturing device 28-31 It is then withdrawn from the pedestal channel wells 22, 23 and reaches the apex of its movable range.
- One or more chutes are provided on the base of the puncture device, and one or more guide rails are arranged in the well guide well to cooperate with the chute on the base of the puncture device for the movement of the puncture base guide.
- the puncturing device base 14 is provided with sliding grooves 32 and 33.
- the pedestal guiding well 22 is provided with guide rails 16-18, wherein the guiding rails 16 and 17 are respectively guided with the sliding grooves 32 and 33, and the guiding rail 18 is located.
- the two flexible infusion hoses 2, 3 can also be guided.
- the trocar base 15 is provided with chutes 34, 35, and the pedestal guide well 23 is provided with guide rails 19-21, wherein the guide rails 19, 20 are respectively engaged with the chutes 34, 35, and the guide rails 19 are located at two Between the flexible infusion hoses 2, 3.
- Example 1 Dissolving drug solution for powdered needle and freeze-dried powder Xilin bottled medicine
- the frame 1 When dissolving the drug, the frame 1 can be connected to the card holder and locked by the buckles on both sides of the frame 1.
- the two elastic infusion hoses 2, 3 are respectively fixed in position on the two peristaltic pumps 39, 38, and the two peristaltic pumps 39, 38 are respectively associated with the two elastic infusion hoses 2, 3 located at the arch 44.
- the two elastic infusion hoses 2, 3 are respectively clamped and fixed between the inner top wall of the arch 44 and the rollers of the corresponding peristaltic pumps 39, 38 for roller rolling.
- the needle setting device in the automatic solvent dispensing system passes through the needle guide holes 4-7, and then penetrates into the perforations 12, 13 of the trocar bases 14, 15, and the puncturing device bases 14, 15 along the pedestal guide wells 22, 23 outwardly, and the elastic infusion hoses 2, 3 connected to the trocar bases 14, 15 during the toggle can be dragged and followed by the puncturing bases 14, 15 in the pedestal wells 22, 23. Movement, the puncturing device 28-31 then pulls out the pedestal guide wells 22, 23, as shown in FIG.
- the puncturing devices 28, 29, which are connected in parallel at one end, can be inserted into the infusion container 36 of the port downward, and the puncturing devices 30, 31 connected in parallel at the other end can be inserted into the vial 37 of the port downward.
- the two peristaltic pumps 39, 38 simultaneously drive the two flexible infusion hoses 2, 3, and the solution in the infusion container 36 is quickly pumped into the vial 37, the duration of which is controlled by an intelligent software program.
- one of the peristaltic pumps 38 (or 39) is reversed, the drive solution is pumped from the vial 37 into the infusion container 36, and the other peristaltic pump 39 (or 38) continues from the infusion container 36 to the Xilin.
- the solution is pumped into the bottle 37 to form a circulating reflux state between the vial 37 and the infusion container 36, and intense turbulence is formed in the vial 37.
- the solution of the vial solution and the undissolved drug are disturbed, and the concentration of the solution in the limited volume of the vial 37 is continuously and rapidly diluted by the continuous infusion and pumping of the infusion, thereby accelerating the dissolution of the drug.
- the two peristaltic pumps 38, 39 completely pump the drug solution in the vial 37 into the infusion container 36. After the pumping is completed, the drug dissolving operation in the vial 37 is completed.
- the two trocar bases 14, 15 are dialed back to the bottom of the pedestal wells 22, 23 by a needle setting device, followed by the puncturing device 28 on the two trocar bases 14, 15.
- the -31 is pulled out from the pierced infusion container 36 and the vial 37, respectively, to complete the drug dissolution process.
- the buckles on both sides of the frame are connected to the card holder and locked, and the two elastic infusion hoses are respectively aligned and fixed on the two peristaltic pumps.
- the puncturing device base in the pedestal guiding well placed at both ends of the frame is dialed out, and then the puncturing device on the two puncturing device bases are simultaneously inserted into the insertion port fixed in the automatic solvent dispensing system. Down into the infusion container and vial.
- the peristaltic pump is used to drive the elastic infusion hose connected with the short puncture of the vial end, and the liquid in the vial is directly pumped into the infusion container; the other channel provides the air pressure balance during the operation. So that the liquid is easily and quickly extracted. After the pumping is completed, the drug preparation operation in the vial is over.
- the puncturing device base is turned back by the needle setting device, and the puncturing devices on the two puncturing device bases are respectively pulled out from the infusion container and the vial bottle, and retracted into the pedestal guide groove well to complete the dispensing operation process.
- the dissolving process can perform the operation of rapidly dissolving the medicine and can realize automation, greatly improve the efficiency of dissolving the medicine, and greatly reduce the labor intensity of the medical staff;
- the medical staff does not need to contact, no need to repeatedly puncture, minimize the spillage and volatilization of the drug during the dispensing process, effectively reduce the harm of the drug to the medical staff during the process of dissolving the drug, and effectively reduce the rubber plug particles in the process of dissolving the drug.
- the pollution of foreign particles and microbes minimizes the exposure of drugs and secondary pollution of drugs, improves the safety of infusion, and helps protect the health of medical personnel and patients.
- the solvent dispenser is designed to be easily installed in an automatic solvent dispensing system for rapid dissolution of formulated drugs for improved efficiency;
- the puncturing device on the base of the two puncturing devices is inserted into the infusion container and the vial at the same time or separately, thereby forming a closed system of two-channel internal communication, which does not need to repeatedly puncture during the process of dissolving the formulated medicine, thereby greatly reducing the medical personnel's Labor intensity; and medical personnel do not need to contact, no need to repeatedly puncture, effectively reduce the harm of drugs to medical staff during the process of dissolving drugs, reduce drug exposure and secondary pollution of drugs, improve the safety of infusion, and help protect medical staff and Patient's health;
- the controllable two-way driving of two peristaltic pumps provides dual-dynamic two-way fluid (such as liquid, gas, liquid-solid mixture) during the dissolution of the drug.
- the fluid In the process of dissolving the drug, the fluid is in the infusion container, the vial and Different flow modes can be formed between the two channels (such as double-directional, double reverse, inner circulation), which can form intense turbulence in the vial, so that the drug in the vial can be quickly dissolved and can pass through the inner circulation.
- the flow mode balances the air pressure in the vial and the infusion container, avoiding the difficulty of the injection of the liquid medicine due to the imbalance of the air pressure during the manual operation and the single-channel operation, thereby rapidly dissolving and transferring the liquid to the infusion container, so that the dissolution efficiency is high.
- the effect of dissolving the drug is good.
- Embodiment 2 is a diagrammatic representation of Embodiment 1:
- the present embodiment provides a solvent dispenser which differs from the first embodiment in that it further includes at least one second elastic infusion hose (not shown) and at least one pair of second puncturing devices (not shown) And, each pair of second puncturing devices includes two second puncturing devices, and the structure of the second puncturing device is the same as that of the puncturing device 28-31.
- one second puncturing device is mounted on the trocar base 14 and the other second puncturing device is mounted on the other puncturing device base 15 and the two second puncturing devices Minute Do not connect to both ends of a second flexible infusion hose, thus forming yet another channel.
- a peristaltic pump is provided at each of the second flexible infusion hoses to drive the flow of liquid within the second flexible infusion hose.
- the solvent dispenser of this embodiment forms three or more channels, making the dissolution of the drug more efficient.
- Embodiment 3 is a diagrammatic representation of Embodiment 3
- the trocar base in this embodiment is fixedly disposed to move within the pedestal guide well and is not movable within the pedestal guide well. In the process of dissolving the drug, the infusion container and the vial can be moved to be pierced by the puncturing device.
- the puncturing device base does not need to be provided with a chute and a needle through hole, and the guide rail and the needle guiding hole are not required on the frame, and the length of the elastic infusion hose need not be set to be stretchable, and can be set to two
- the distance between the bases of the piercers is adapted to simplify the structure of the drug dispenser.
- the solvent dispenser of the present application can be used not only for the dissolution of the vials, but also for other, such as two infusion containers.
- the embodiments of the present application improve the efficiency of dissolving the medicine, and greatly reduce the labor intensity of the medical staff; the medical staff does not need to contact, and does not need to repeatedly puncture, effectively reducing the harm of the medicine to the medical staff during the dissolution of the medicine, and reducing the exposure of the medicine. And secondary pollution of drugs, improve the safety of infusion, and help protect the health of medical staff and patients.
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Abstract
一种溶配药器,用于自动溶配药,包括:两个穿刺器基座(14,15);四根第一穿刺器(28-31),其中两根(28,29)安装在一穿刺器基座(14)上,另两根(30,31)安装在另一穿刺器基座(15)上;两根第一弹性输液软管(2,3),一根第一弹性输液软管(2)的两端分别与安装在两个穿刺器基座(14,15)上的两根第一穿刺器(29,30)的内通道的底端相连通,另一根第一弹性输液软管(3)的两端分别与安装在两个穿刺器基座(14,15)上的另两根第一穿刺器(28,31)的内通道的底端相连通。在溶配药器使用时,一穿刺器基座(14)上的两根第一穿刺器(28,29)刺穿一盛药容器(36);另一穿刺器基座(15)上的两根第一穿刺器(30,31)刺穿另一盛药容器(37);并且在每根第一弹性输液软管(2,3)处均设有蠕动泵,蠕动泵工作挤压两根第一弹性输液软管(2,3),使两盛药容器(36,37)内的内容物互相流动、混合,进行溶配药。
Description
本申请实施例涉及但不限于输液配药器械领域,特别是一种用于自动溶配药的溶配药器。
现有的输液溶配药基本在使用注射器及其他简易的形式手工配药,在配药的过程中,不能连续配制,效率低,速度慢,劳动强度大;西林瓶包装药品配制时,由于多次穿刺西林瓶及输液容器的胶塞,容易造成漏液及微粒污染;在配制细胞毒性药物、化疗药物、易致敏药物、高活性等药物时,多次穿刺西林瓶及输液容器的胶塞,易产生药物溅出和挥发,对于配药人员造成长期伤害,可能带来不可逆的后果;多次穿刺西林瓶及输液容器的胶塞,由于针头暴露在非无菌环境,微生物会污染针头,污染的微生物可能会随着多次穿刺造成输液微生物二次污染;人工操作易受到操作人员精神状态和配药速度要求的影响,国家要求医疗机构配药中心的建立,需要配药方式的革新,以迄自动化、高效率、无污染的配药方式出现。
发明内容
现有的一次性输液器材和一次性溶配药器,穿刺器暴露在外,人工进行配药时,容易扎伤,且配药速度慢,不适应自动化配制,操作过程中多次穿刺,非全封闭配制,对于较难溶药物,需较长时间的震荡操作进行溶解。冻干粉针剂(西林瓶装)在生产过程中可产生微真空,普通溶药配制过程中,因瓶内有微真空,操作人员很难直接抽出溶解的药液,操作人员需要先重复穿刺将瓶内气压平衡,才能抽出药液。
为了克服以上缺点,本申请实施例提供了一种溶配药器。
本申请实施例提供的溶配药器,其用于自动溶配药,包括:
框架;
两个穿刺器基座,其安装在所述框架内;
四根第一穿刺器,每一根所述第一穿刺器设有贯通的内通道,且顶端具有尖锐的穿刺部,两根所述第一穿刺器安装在一所述穿刺器基座上,另两根所述第一穿刺器安装在另一所述穿刺器基座上;和
两根第一弹性输液软管,一根所述第一弹性输液软管的两端分别与安装在两个所述穿刺器基座上的两根所述第一穿刺器的内通道的底端相连通,另一根所述第一弹性输液软管的两端分别与安装在两个所述穿刺器基座上的另两根所述第一穿刺器的内通道的底端相连通;
其中,在所述溶配药器使用时,一所述穿刺器基座上的两根所述第一穿刺器配置成刺穿一盛药容器并与该盛药容器相连通;另一所述穿刺器基座上的两根所述第一穿刺器配置成刺穿另一盛药容器与该另一盛药容器相连通;并且两根所述第一弹性输液软管配置成在每根所述第一弹性输液软管处均设有蠕动泵,两个所述蠕动泵工作挤压两根所述第一弹性输液软管,使两所述盛药容器内的内容物互相流动、混合,进行溶配药。
可选地,两个所述穿刺器基座中的至少一个可移动地安装在所述框架内,每一所述第一弹性输液软管的长度均大于两个所述穿刺器基座之间的距离且不限制所述框架的移动;
其中,在所述溶配药器使用前,可移动的所述穿刺器基座上的所述第一穿刺器收藏于所述框架内;在所述溶配药器使用时,可移动的所述穿刺器基座移动使其上的所述第一穿刺器伸出所述框架。
可选地,两个所述穿刺器基座均可移动地安装在所述框架内。
可选地,所述框架上设有对应于可移动的所述穿刺器基座的拨针导
孔,所述拨针导孔为贯穿所述框架的壁的通孔;
在所述溶配药器使用时,穿过所述拨针导孔并沿所述拨针导孔带动可移动的所述穿刺器基座移动。
可选地,所述拨针导孔的长度设置成使可移动的所述穿刺器基座可移动至可移动的所述穿刺器基座的上表面与所述框架的上表面平齐。
可选地,可移动的所述穿刺器基座上设有拨针穿孔,
在所述溶配药器使用时,通过所述拨针穿孔带动可移动的所述穿刺器基座沿所述拨针导孔移动。
可选地,所述框架的内侧壁和移动的所述穿刺器基座的外侧壁中的一个上设有导轨,另一个上设有滑槽,所述导轨与所述滑槽配合并能相对于所述滑槽移动。
可选地,所述框架的两侧均设有基座导槽井,且每一基座导槽井的内侧壁上均设有导轨;
两个所述穿刺器基座分别位于两侧的所述基座导槽井内,并设有与所述导轨配合的滑槽。
可选地,两个所述穿刺器基座中的至少一个固定地安装在所述框架内,
其中,在所述溶配药器使用时,与固定的所述穿刺器基座对应的所述盛药容器移动以被固定的所述穿刺器基座移动上的所述第一穿刺器刺穿。
可选地,两所述穿刺器基座中的至少一个上的两根所述第一穿刺器的长度相同或不同。
可选地,每一所述穿刺器基座上的两根所述第一穿刺器的长度均不同;
且每一所述穿刺器基座上的两根所述穿刺器中,短的所述穿刺器露
出所述穿刺器基座的部分的长度为8-10mm,长的所述穿刺器露出所述穿刺器基座的部分的长度不长于28mm。
可选地,所述框架的下端的中部设有弧形的凹陷部,所述凹陷部两侧的壁面上均分别设有供两根所述第一弹性输液软管穿过的两个通孔;
且所述凹陷部的形状配置成与两个所述蠕动泵的滚轮旋转的弧度相适配。
可选地,所述框架的外壁面上设有卡扣,所述卡扣配置成与卡座相卡接。
可选地,所述溶配药器还包括:
至少一根第二弹性输液软管;和
至少一对第二穿刺器,每对第二穿刺器包括两根第二穿刺器,且所述第二穿刺器的结构与所述第一穿刺器的结构相同;
在每对第二穿刺器中,一根所述第二穿刺器安装在一所述穿刺器基座上,另一根所述第二穿刺器安装在另一所述穿刺器基座上,且两根所述第二穿刺器分别与一根所述第二弹性输液软管的两端相连;
且至少一根所述第二弹性输液软管配置成在每根所述第二弹性输液软管处均设有蠕动泵。
本申请实施例还提供了一种一次性西林瓶溶配药器,用于自动溶配药***,包括由四根穿刺器、两根弹性输液软管、两个穿刺器基座及一个框架构成,
穿刺器中空并形成内通道,且穿刺器的顶端开孔以与内通道连通并制成尖锐状,底端也开孔以与内通道连通,
每根弹性输液软管的两端分别与一根穿刺器的底端相连通,形成一个通道,且两个所述通道平行;两个通道每端的两根穿刺器固定在一个穿刺器基座上;
框架呈拱桥状,且两端为基座导槽井,两个穿刺器基座分别置于框架两端的基座导槽井内;框架的中下部具有弧状区域,被称为拱门,拱门的形状与两个蠕动泵的滚轮旋转的弧度相适配,且拱门的两内侧壁上均分别贯穿与相邻的基座导槽井连通的两条平行孔道,两根弹性输液软管从孔道穿过并与两端的基座导槽井内的穿刺器基座上的穿刺器连接,弹性输液软管被固定在孔道内;
未使用时,两个穿刺器基座位于基座导槽井的底部,且四根穿刺器均收藏于基座导槽井内;
使用时,穿刺器基座配置成通过所述自动溶配药***中的拨针装置沿基座导槽井被向外拨动,且弹性输液软管被拖动而跟随穿刺器基座运动,穿刺器随之被拨出基座导槽井,此时,一端的两根穿刺器配置成***输液容器内,另一端的两根穿刺器配置成***西林瓶内;且两根弹性输液软管配置成分别与所述自动溶配药***的一个外接蠕动泵对应,且两根弹性输液软管被分别夹紧固定在拱门的内顶壁与相对应的蠕动泵滚轮之间,以被滚轮碾压,依靠蠕动泵的动力驱动弹性输液软管内的流体流动,进行相应的溶配操作。
可选地,四根穿刺器的材质为医用不锈钢或医用塑料。
可选地,两根弹性输液软管皆由医用塑料材质制成。
可选地,每个穿刺器基座上的两根穿刺器包括短穿刺器和长穿刺器,且短穿刺器露出穿刺器基座部分的长度为8-10mm,长穿刺器露出穿刺器基座部分的长度不长于28mm;或者每个穿刺器基座上的两根穿刺器为同等长度的穿刺器;
穿刺器基座上有拨针穿孔,拨针穿孔配置成供所述自动溶配药***的拨动装置穿入,以拨动穿刺器基座;且穿刺器基座上设有一个或多个滑槽供其在被拨动时导向。
可选地,基座导槽井内设有一根或多根导轨,用于与穿刺器基座上
的滑槽配合,以为穿刺器基座移动进行导向;
两个基座导槽井两侧均开有长度相等的拨针导孔,且拨针导孔的长度设置成使穿刺器基座被拨出后穿刺器基座的上平面与框架的上表面达到同一平面;
拱门的两内侧壁上的四条孔道的开口均处于同一水平高度,且拱门的一内侧壁上一条孔道的轴心线与拱门的另一内侧壁上的相对应的孔道的轴心线处于同一直线上;拱门的一内侧壁上的另一条孔道的轴心线与拱门的另一内侧壁上相对应的孔道的轴心线处于另外的同一直线上,且两个直线相互平行。
可选地,将一次性西林瓶溶配药器卡定在自动溶配药***的卡座上,弹性输液软管可被夹紧固定在框架拱门内顶壁与蠕动泵的滚轮之间,然后拨针装置穿过拨针导孔,再穿入拨针穿孔中,将两个穿刺器基座沿基座导槽井向外拨动,两个穿刺器基座上的穿刺器同时或分别刺入输液容器和西林瓶中,从而形成双通道内联通封闭***。
可选地,通过两个蠕动泵的可控双向驱动,在溶配药过程中提供双动力双向流体输送,在溶配药物过程中,流体在输液容器、西林瓶及两个通道之间根据需要形成不同的流动方式,在西林瓶内形成激烈的湍流,使西林瓶内药物快速溶解,并能平衡西林瓶和输液容器内的气压,以快速溶配转移药液至输液容器内;西林瓶内药物完全溶解并转移至输液容器后,通过拨针装置将两个穿刺器基座同时或分别拨回至基座导槽井底部,随之两个基座上的穿刺器从输液容器和西林瓶中拔出,完成药物溶配操作。
本申请实施例提供的溶配药器,在溶配药过程中不需将穿刺器反复***抽出,可实现全封闭的溶配药过程,既减轻了配药的劳动强度,同时实现了连续配制,效率提高;此外避免造成漏液及漏液对配药人员造成的伤害;同时减少或避免了微粒污染、微生物的二次污染。本申请的实施例实现了自动化、高效率、无污染的配药。
以上是对本文详细描述的主题的概述。本概述并非是为了限制权利要求的保护范围。
在阅读并理解了附图概述和本发明的实施方式后,可以明白其他方面。
附图概述
当结合附图考虑时,通过参照下面的详细描述,能够更完整更好地理解本申请实施例以及容易得知其中许多伴随的优点,但此处所说明的附图用来提供对本申请实施例的进一步理解,构成本申请实施例的一部分,本申请的示意性实施例及其说明用于解释本申请,并不构成对本申请的不当限定,如图其中:
图1是本申请实施例的溶配药器未使用状态的结构示意图;
图2是本申请实施例的溶配药器使用状态的结构示意图;
图3是本申请实施例的溶配药器未使用状态的透视结构示意图;
图4是本申请实施例的溶配药器省去框架后未使用状态的结构示意图;
图5是本申请实施例的溶配药器省去框架后使用状态的结构示意图;
图6是本申请实施例的溶配药器的框架的结构示意图;以及
图7是本申请实施例的溶配药器用于自动溶配药***的结构示意图。
显然,本领域技术人员基于本申请的宗旨所做的许多修改和变化属于本申请的保护范围。
实施例一:
如图1-图7所示,本实施例提供了一种用于自动溶配药***的一次
性西林瓶溶配药器,其由四根穿刺器28-31、两根弹性输液软管2-3、两个穿刺器基座14-15及一个框架1组成。
其中,如图4所示,穿刺器28-31中空,形成内通道,且穿刺器28-31顶端开孔,并可制成尖锐状,且与内通道连通,底端也开孔与内通道连通。
弹性输液软管2的两端分别与穿刺器29、30的底端相连通,此组成结构可定义为一个通道,该通道的弹性输液软管2可固定在自动溶配药***的一个外接蠕动泵39上,由蠕动泵39提供动力,驱动弹性输液软管2内的流体(如:液体、气体、液固混合体)流动;弹性输液软管3的两端分别与穿刺器28、31的底端相连通,此组成结构可定义为一个通道,该通道的弹性输液软管3可固定在自动溶配药***的一个外接蠕动泵38上,由蠕动泵38提供动力,驱动弹性输液软管3内的流体(如:液体、气体、液固混合体)流动。在图4和图5中,标号24-27为弹性输液软管2、3与穿刺器28-31的连接处。
本溶配药器的两个通道平行,且每端的两个穿刺器28、29以及30、31分别固定在一个穿刺器基座14、15上并呈并联状态。
如图6所示,框架1呈拱桥状,两端为基座导槽井22、23,两个穿刺器基座14、15分别置于框架1两端的基座导槽井22、23内,且可相对于基座导槽井22、23滑动。
溶配药器未使用时,如图1和图4所示,穿刺器基座14、15位于基座导槽井22、23的底部,此时穿刺器28-31均收藏于基座导槽井22、23内;溶配药器使用时,自动溶配药***中的拨针装置(未示出)将穿刺器基座14、15分别沿基座导槽井22、23向外拨动,拨动时穿刺器基座14、15上连接的弹性输液软管2、3可被拖动跟随穿刺器基座14、15运动,穿刺器28-31随之被拨出基座导槽井22、23,使穿刺器28-31的顶端伸出(如图2和图5所示);此时,如图7所示,一端并联的穿刺器28、29可***输液容器36内,另一端并联的穿刺器30、31可***
西林瓶37内。这样,在输液容器36和西林瓶37之间形成流体流通的通路。
需要说明的是,两根弹性输液软管2、3的长度均大于两穿刺器基座14、15之间的距离。因此,在未使用时,两根弹性输液软管2、3均处于未张紧状态,如两根弹性输液软管2、3可盘绕起来,以节省空间。
如图6所示,框架1的中下部具有的弧状区域被称之为拱门44,其拱门状设计主要是为了配合自动溶配药***中的两个蠕动泵38、39的滚轮旋转的弧度。拱门44两内侧壁上分别贯穿两条平行孔道40-43,且平行孔道40、41与相邻的基座导槽井23连通,平行孔道42、43与相邻的基座导槽井22连通。两根弹性输液软管2、3的两端分别从拱门44两内侧壁上的孔道40-43穿过并与两侧的基座导槽井22、23内固定在穿刺器基座14、15上的穿刺器28-31连接,弹性输液软管2、3可被固定在孔道40-43内。
进一步,拱门44两内侧壁上的四条平行孔道40-43均处于同一水平高度,且拱门44一内侧壁上的一条孔道42的轴心线与拱门44另一内侧壁上相对应的孔道40的轴心线处于同一直线上,拱门44一内侧壁上另一条孔道42的轴心线与拱门44另一内侧壁上相对应的孔道41的轴心线处于另外的同一直线上,以上所述的两条直线相互平行。这样,位于拱门44内的两根弹性输液软管2、3相互平行。
如图6所示,框架1两侧设有卡扣,一侧的卡扣具有卡扣导面8和卡扣平面10,另一侧的卡扣具有卡扣导面9和卡扣平面11。两个卡扣可与自动溶配药***的卡座(未示出)相连并卡定。当框架1固定在卡座上后,本溶配药器的两根弹性输液软管2、3分别与两个蠕动泵39、38对位固定。两根弹性输液软管2、3被分别夹紧固定在拱门44的内顶壁与相对应的蠕动泵39、38的滚轮之间,可供滚轮碾压,依靠蠕动泵38、39的动力进行相应的溶配操作。
弹性输液软管2、3具有弹性,以便滚轮碾压过后其能够回复至其
原始形状,以便滚轮进行下一次的挤压,驱动弹性输液软管2、3内的流体流动,进而实现输液容器36和西林瓶37中的药物进行溶配操作。
溶配药器的四根穿刺器28-31的材质为医用不锈钢或医用PVC等医用塑料,以符合医用标准。
溶配药器的两根弹性输液软管2、3皆由医用塑料材质(如:医用PVC、TPE、TPU、医用硅胶等材质)制成。
每个穿刺器基座上的两个穿刺器可设计为具有不同长度或同等长度。如图4所示,穿刺器基座14上具有短穿刺器29和长穿刺器28,穿刺器基座15上具有短穿刺器31和长穿刺器30,其中短穿刺器29和长穿刺器30与弹性输液软管2的两端相连,短穿刺器31和长穿刺器28与弹性输液软管3的两端相连。每个穿刺器基座上实现长短穿刺器的设计配合主要是在双通道动力配合下能够在西林瓶内产生更剧烈的湍流,促进药物溶解。
进一步,短穿刺器31露出穿刺器基座15的部分的长度为8-10mm,以保证西林瓶37内的药液能够尽可能被吸出;长穿刺器30露出穿刺器基座15的部分的长度不长于28mm,不超过2ml的西林瓶37的高度(通常为28mm),以防止刺裂西林瓶37。
两个基座导槽井22的两侧均开有长度相等的拨针导孔4-7,穿刺器基座14、15上设有拨针穿孔12、13。自动溶配药***的拨针装置穿过拨针导孔4-7并穿入穿刺器基座14、15的拨针穿孔12、13,以拨动穿刺器基座14、15。其中,拨针导孔4-7的长度能使穿刺器基座14、15被拨出后,穿刺器基座14、15的上平面与框架1的上表面达到同一平面,穿刺器28-31随之被拨出基座导槽井22、23并达到其可移动范围的顶点。
穿刺器基座上设有一个或多个滑槽,基座导槽井内设有一根或多根导轨,用于与穿刺器基座上的滑槽配合,以便为穿刺器基座的移动进行导向。
具体地,穿刺器基座14上设有滑槽32、33,基座导槽井22内设有导轨16-18,其中导轨16、17分别与滑槽32、33配合进行导向,导轨18位于两根弹性输液软管2、3之间,也可以进行导向。同样地,穿刺器基座15上设有滑槽34、35,基座导槽井23内设有导轨19-21,其中导轨19、20分别与滑槽34、35配合,导轨19位于两根弹性输液软管2、3之间。
下面结合具体示例说明本实施例的溶配药器进行溶配药的过程。
示例一:粉针、冻干粉针西林瓶装药品的溶配药方案
未进行溶配药时,溶配药器的状态如图1所示。
进行溶配药时,首先通过框架1两边的卡扣将框架1可与卡座相连并卡定。两根弹性输液软管2、3随之分别对位固定在两个蠕动泵39、38上,且两个蠕动泵39、38分别与位于拱门44处的两根弹性输液软管2、3相对应,两根弹性输液软管2、3被分别夹紧固定在拱门44的内顶壁与相对应的蠕动泵39、38的滚轮之间,可供滚轮碾压。
自动溶配药***中的拨针装置穿过拨针导孔4-7,再穿入穿刺器基座14、15的穿孔12、13中,将穿刺器基座14、15沿基座导槽井22、23向外拨动,拨动时与穿刺器基座14、15连接的弹性输液软管2、3在基座导槽井22、23内可被拖动跟随穿刺器基座14、15运动,穿刺器28-31随之拨出基座导槽井22、23,如图2所示。
然后,一端并联的穿刺器28、29可***端口向下的输液容器36内,另一端并联的穿刺器30、31可***端口向下的西林瓶37内。两个蠕动泵39、38同时驱动两根弹性输液软管2、3,将输液容器36内的溶液快速泵入西林瓶37中,泵液的持续时间由智能软件程序控制。泵入结束后,将其中一个蠕动泵38(或39)反向,驱动溶液从西林瓶37内泵入输液容器36中,另一个蠕动泵39(或38)则继续从输液容器36中向西林瓶37内泵入溶液,从而在西林瓶37和输液容器36之间形成循环回流状态,并在西林瓶37内形成激烈的湍流。在溶配过程中,持续剧
烈扰动西林瓶药液和未溶解的药物,且通过输液持续动态的泵入、泵出,使西林瓶37内有限容积的溶液浓度被不断快速稀释,从而使药物加快溶解。药物完全溶解后,两个蠕动泵38、39将西林瓶37内的药液完全泵入输液容器36内,泵液结束后,西林瓶37内的药品溶配操作结束。
溶配药过程完成后,通过拨针装置将两个穿刺器基座14、15拨回至基座导槽井22、23的底部,随之两个穿刺器基座14、15上的穿刺器28-31分别从刺入的输液容器36和西林瓶37中拔出,完成药物溶配过程。
示例二:液体西林瓶配药方案
将框架两边的卡扣与卡座相连并卡定,两根弹性输液软管随之分别对位固定在两个蠕动泵上。
通过拨针装置,将置于框架两端的基座导槽井内的穿刺器基座拨出,随之两个穿刺器基座上的穿刺器同时分别刺入固定在自动溶配药***中的***端口向下的输液容器和西林瓶中。
通过智能软件程序控制,用蠕动泵驱动与西林瓶端的短穿刺器相连通的弹性输液软管,将西林瓶内的药液直接泵入输液容器中;另一通道则在操作过程中提供气压平衡,使药液很容易迅速抽出。泵液结束后,西林瓶内的药品配制操作结束。
通过拨针装置将穿刺器基座拨回,随之两个穿刺器基座上的穿刺器分别从输液容器和西林瓶中拔出,并收回到基座导槽井内,完成配药操作的过程。
上述两个具体实施方案显示,所述溶配过程可进行快速溶配药品的操作并可实现自动化,极大地提高溶配药品的效率,大大降低了医护人员的劳动强度;由于在溶解配制药物过程中,医护人员无需接触,无需反复进行穿刺,配药过程中尽可能减少药物溅出和挥发,有效降低溶配药过程中药物对医护人员的伤害,在溶配药过程中有效减少胶塞颗粒脱
离、外界微粒、微生物的污染,最大限度地降低了药品暴露和药品二次污染,提高了输液安全性,有利于保护医护人员和患者的健康。
本实施例的溶配药器具有如下有益效果:
溶配药器的设计可使其便于安装在自动溶配药***中,进行快速溶解配制药物,提高了效率;
两个穿刺器基座上的穿刺器同时或分别刺入输液容器和西林瓶中,从而形成双通道内联通的封闭***,在溶解配制药物过程中,无需反复进行穿刺,大大降低了医护人员的劳动强度;且医护人员无需接触,无需反复进行穿刺,有效降低溶配药过程中药物对医护人员的伤害,同时降低了药品暴露和药品二次污染,提高了输液安全性,有利于保护医护人员和患者的健康;
通过两个蠕动泵的可控双向驱动,在溶配药过程中提供双动力双向流体(如:液体、气体、液固混合体)输送,在溶配药物过程中,流体在输液容器、西林瓶及两个通道之间可根据需要形成不同的流动方式(如双同向、双反向、内循环),可在西林瓶内形成激烈的湍流,使西林瓶内药物快速溶解,并能通过内循环的流动方式平衡西林瓶和输液容器内气压,避免人工操作和单通道操作时气压不平衡造成药液抽出注入困难的情况,从而可快速溶配转移药液至输液容器内,使得溶配效率高,溶配药的效果好。
实施例二:
本实施例提供了一种溶配药器,其与实施例一的不同之处在于:其还包括至少一根第二弹性输液软管(未示出)和至少一对第二穿刺器(未示出),每对第二穿刺器包括两根第二穿刺器,且第二穿刺器的结构与穿刺器28-31的结构相同。
在每对第二穿刺器中,一根第二穿刺器安装在一穿刺器基座14上,另一根第二穿刺器安装在另一穿刺器基座15上,且两根第二穿刺器分
别与一根第二弹性输液软管的两端相连,这样形成了又一个通道。
在每根第二弹性输液软管处均设有蠕动泵,以驱动第二弹性输液软管内的液体流动。
本实施例的溶配药器,其形成了三个或三个以上的通道,使得溶配药的效率更高。
实施例三:
本实施例提供了一种溶配药器,其与实施例一的不同之处在于:
本实施例中的穿刺器基座固定地设置在基座导槽井内移动,不可在基座导槽井内移动。在溶配药的过程中,可移动输液容器和西林瓶,以被穿刺器刺穿。
因此,本实施例中的穿刺器基座上无需设置滑槽、拨针穿孔,框架上无需设置导轨、拨针导孔,弹性输液软管的长度无需设置为可拉伸,可设置成与两穿刺器基座之间的距离相适配,使得溶配药器的结构简化。
需要说明的是,以上实施例仅是本申请的具体的实现方式,还可以存在其他实现方式,如:两个穿刺器基座中,一个是可移动的,另一个是固定的;或任何移动与固定的组合;可通过在框架上设置限位装置来限制穿刺器基座的移动等。
本申请的溶配药器不仅可用于西林瓶的溶配药,还可以用于其他,如两个输液容器等。
在本申请的描述中,术语“多个”指两个或多于两个。
以上公开内容规定为说明性的而不是穷尽性的。对于本领域技术人员来说,本说明书将暗示许多变化和可选择方案。所有这些可选择方案和变化规定为被包括在本权利要求的范围内。本领域技术人员应认识到此处所述的实施方案的其它等效变换,这些等效变换也规定为由本权利要求所包括。
在此完成了对本申请可选择的实施方案的描述。本领域技术人员可
认识到此处所述的实施例仅用于说明本申请,其中溶配药器的元件或结构等都是可以有所变化的,凡是在本申请技术方案的基础上进行的等同变换和改进,均不应被排除在本申请的保护范围之外。
本申请实施例,提高了溶配药品的效率,大大降低了医护人员的劳动强度;医护人员无需接触,无需反复进行穿刺,有效降低溶配药过程中药物对医护人员的伤害,且降低了药品暴露和药品二次污染,提高了输液安全性,有利于保护医护人员和患者的健康。
Claims (21)
- 一种溶配药器,其用于自动溶配药,包括:框架;两个穿刺器基座,其安装在所述框架内;四根第一穿刺器,每一根所述第一穿刺器设有贯通的内通道,且顶端具有尖锐的穿刺部,两根所述第一穿刺器安装在一所述穿刺器基座上,另两根所述第一穿刺器安装在另一所述穿刺器基座上;和两根第一弹性输液软管,一根所述第一弹性输液软管的两端分别与安装在两个所述穿刺器基座上的两根所述第一穿刺器的内通道的底端相连通,另一根所述第一弹性输液软管的两端分别与安装在两个所述穿刺器基座上的另两根所述第一穿刺器的内通道的底端相连通;其中,在所述溶配药器使用时,一所述穿刺器基座上的两根所述第一穿刺器配置成刺穿一盛药容器并与该盛药容器相连通;另一所述穿刺器基座上的两根所述第一穿刺器配置成刺穿另一盛药容器与该另一盛药容器相连通;并且两根所述第一弹性输液软管配置成在每根所述第一弹性输液软管处均设有蠕动泵,两个所述蠕动泵工作挤压两根所述第一弹性输液软管,使两所述盛药容器内的内容物互相流动、混合,进行溶配药。
- 如权利要求1所述的溶配药器,其中两个所述穿刺器基座中的至少一个可移动地安装在所述框架内,每一所述第一弹性输液软管的长度均大于两个所述穿刺器基座之间的距离且不限制所述框架的移动;其中,在所述溶配药器使用前,可移动的所述穿刺器基座上的所述第一穿刺器收藏于所述框架内;在所述溶配药器使用时,可移动的所述穿刺器基座移动使其上的所述第一穿刺器伸出所述框架。
- 如权利要求2所述的溶配药器,其中两个所述穿刺器基座均可移动地安装在所述框架内。
- 如权利要求2或3所述的溶配药器,其中所述框架上设有对应于可移动的所述穿刺器基座的拨针导孔,所述拨针导孔为贯穿所述框架的壁的通孔;在所述溶配药器使用时,穿过所述拨针导孔并沿所述拨针导孔带动可移动的所述穿刺器基座移动。
- 如权利要求4所述的溶配药器,其中所述拨针导孔的长度设置成使可移动的所述穿刺器基座可移动至可移动的所述穿刺器基座的上表面与所述框架的上表面平齐。
- 如权利要求5所述的溶配药器,其中可移动的所述穿刺器基座上设有拨针穿孔,在所述溶配药器使用时,通过所述拨针穿孔带动可移动的所述穿刺器基座沿所述拨针导孔移动。
- 如权利要求2-6中任一项所述的溶配药器,其中所述框架的内侧壁和移动的所述穿刺器基座的外侧壁中的一个上设有导轨,另一个上设有滑槽,所述导轨与所述滑槽配合并能相对于所述滑槽移动。
- 如权利要求3所述的溶配药器,其中所述框架的两侧均设有基座导槽井,且每一基座导槽井的内侧壁上均设有导轨;两个所述穿刺器基座分别位于两侧的所述基座导槽井内,并设有与所述导轨配合的滑槽。
- 如权利要求1所述的溶配药器,其中两个所述穿刺器基座中的至少一个固定地安装在所述框架内,其中,在所述溶配药器使用时,与固定的所述穿刺器基座对应的所述盛药容器移动以被固定的所述穿刺器基座移动上的所述第一穿刺器刺穿。
- 如权利要求1-9中任一项所述的溶配药器,其中两所述穿刺器基座中的至少一个上的两根所述第一穿刺器的长度相同或不同。
- 如权利要求10所述的溶配药器,其中每一所述穿刺器基座上的两根所述第一穿刺器的长度均不同;且每一所述穿刺器基座上的两根所述穿刺器中,短的所述穿刺器露出所述穿刺器基座的部分的长度为8-10mm,长的所述穿刺器露出所述穿刺器基座的部分的长度不长于28mm。
- 如权利要求1-11中任一项所述的溶配药器,其中所述框架的下端的中部设有弧形的凹陷部,所述凹陷部两侧的壁面上均分别设有供两根所述第一弹性输液软管穿过的两个通孔;且所述凹陷部的形状配置成与两个所述蠕动泵的滚轮旋转的弧度相适配。
- 如权利要求1-12中任一项所述的溶配药器,其中所述框架的外壁面上设有卡扣,所述卡扣配置成与卡座相卡接。
- 如权利要求1-13中任一项所述的溶配药器,还包括:至少一根第二弹性输液软管;和至少一对第二穿刺器,每对第二穿刺器包括两根第二穿刺器,且所述第二穿刺器的结构与所述第一穿刺器的结构相同;在每对第二穿刺器中,一根所述第二穿刺器安装在一所述穿刺器基座上,另一根所述第二穿刺器安装在另一所述穿刺器基座上,且两根所述第二穿刺器分别与一根所述第二弹性输液软管的两端相连;且至少一根所述第二弹性输液软管配置成在每根所述第二弹性输液软管处均设有蠕动泵。
- 一种一次性西林瓶溶配药器,用于自动溶配药***,包括由四根穿刺器、两根弹性输液软管、两个穿刺器基座及一个框架构成,穿刺器中空并形成内通道,且穿刺器的顶端开孔以与内通道连通并制成尖锐状,底端也开孔以与内通道连通,每根弹性输液软管的两端分别与一根穿刺器的底端相连通,形成一个通道,且两个所述通道平行;两个通道每端的两根穿刺器固定在一个穿刺器基座上;框架呈拱桥状,且两端为基座导槽井,两个穿刺器基座分别置于框架两端的基座导槽井内;框架的中下部具有弧状区域,被称为拱门,拱门的形状与两个蠕动泵的滚轮旋转的弧度相适配,且拱门的两内侧壁上均分别贯穿与相邻的基座导槽井连通的两条平行孔道,两根弹性输液软管从孔道穿过并与两端的基座导槽井内的穿刺器基座上的穿刺器连接,弹性输液软管被固定在孔道内;未使用时,两个穿刺器基座位于基座导槽井的底部,且四根穿刺器均收藏于基座导槽井内;使用时,穿刺器基座配置成通过所述自动溶配药***中的拨针装置沿基座导槽井被向外拨动,且弹性输液软管被拖动而跟随穿刺器基座运动,穿刺器随之被拨出基座导槽井,此时,一端的两根穿刺器配置成***输液容器内,另一端的两根穿刺器配置成***西林瓶内;且两根弹性输液软管配置成分别与所述自动溶配药***的一个外接蠕动泵对应,且两根弹性输液软管被分别夹紧固定在拱门的内顶壁与相对应的蠕动泵滚轮之间,以被滚轮碾压,依靠蠕动泵的动力驱动弹性输液软管内的流体流动,进行相应的溶配操作。
- 根据权利要求15所述的一次性西林瓶溶配药器,其中四根穿刺器的材质为医用不锈钢或医用塑料。
- 根据权利要求15或16所述的一次性西林瓶溶配药器,其中两根弹性输液软管皆由医用塑料材质制成。
- 根据权利要求15-17中任一项所述的一次性西林瓶溶配药器,其中每个穿刺器基座上的两根穿刺器包括短穿刺器和长穿刺器,且短穿刺器露出穿刺器基座部分的长度为8-10mm,长穿刺器露出穿刺器基座部分的长度不长于28mm;或者每个穿刺器基座上的两根穿刺器为同等 长度的穿刺器;穿刺器基座上有拨针穿孔,拨针穿孔配置成供所述自动溶配药***的拨动装置穿入,以拨动穿刺器基座;且穿刺器基座上设有一个或多个滑槽供其在被拨动时导向。
- 根据权利要求18所述的一次性西林瓶溶配药器,其中基座导槽井内设有一根或多根导轨,用于与穿刺器基座上的滑槽配合,以为穿刺器基座移动进行导向;两个基座导槽井两侧均开有长度相等的拨针导孔,且拨针导孔的长度设置成使穿刺器基座被拨出后穿刺器基座的上平面与框架的上表面达到同一平面;拱门的两内侧壁上的四条孔道的开口均处于同一水平高度,且拱门的一内侧壁上一条孔道的轴心线与拱门的另一内侧壁上的相对应的孔道的轴心线处于同一直线上;拱门的一内侧壁上的另一条孔道的轴心线与拱门的另一内侧壁上相对应的孔道的轴心线处于另外的同一直线上,且两条直线相互平行。
- 根据权利要求18所述的一次性西林瓶溶配药器,其中将一次性西林瓶溶配药器卡定在自动溶配药***的卡座上,弹性输液软管可被夹紧固定在框架拱门内顶壁与蠕动泵的滚轮之间,然后拨针装置穿过拨针导孔,再穿入拨针穿孔中,将两个穿刺器基座沿基座导槽井向外拨动,两个穿刺器基座上的穿刺器同时或分别刺入输液容器和西林瓶中,从而形成双通道内联通封闭***。
- 根据权利要求15-20中任一项所述的一次性西林瓶溶配药器,其中通过两个蠕动泵的可控双向驱动,在溶配药过程中提供双动力双向流体输送,在溶配药物过程中,流体在输液容器、西林瓶及两个通道之间根据需要形成不同的流动方式,在西林瓶内形成激烈的湍流,使西林瓶内药物快速溶解,并能平衡西林瓶和输液容器内的气压,以快速溶配转移药液至输液容器内;西林瓶内药物完全溶解并转移至输液容器后, 通过拨针装置将两个穿刺器基座同时或分别拨回至基座导槽井底部,随之两个基座上的穿刺器从输液容器和西林瓶中拔出,完成药物溶配操作。
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