WO2016153211A3 - 감귤류 과피 추출물의 제조방법 및 간 손상 예방, 개선 또는 치료용 조성물 - Google Patents

감귤류 과피 추출물의 제조방법 및 간 손상 예방, 개선 또는 치료용 조성물 Download PDF

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WO2016153211A3
WO2016153211A3 PCT/KR2016/002606 KR2016002606W WO2016153211A3 WO 2016153211 A3 WO2016153211 A3 WO 2016153211A3 KR 2016002606 W KR2016002606 W KR 2016002606W WO 2016153211 A3 WO2016153211 A3 WO 2016153211A3
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citrus peel
peel extract
present
liver damage
alleviating
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PCT/KR2016/002606
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English (en)
French (fr)
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WO2016153211A2 (ko
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최봉근
서동아
서동은
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주식회사 뉴트라팜텍
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Publication of WO2016153211A2 publication Critical patent/WO2016153211A2/ko
Publication of WO2016153211A3 publication Critical patent/WO2016153211A3/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00—Function of food ingredients
    • A23V2200/30—Foods, ingredients or supplements having a functional effect on health
    • A23V2200/32—Foods, ingredients or supplements having a functional effect on health having an effect on the health of the digestive tract
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

본 발명의 일 예는 감귤류 과피로부터 노빌레틴(nobiletin) 및 탄저레틴(tangeretin)의 함량이 높은 추출물을 제조하는 방법을 제공한다. 본 발명에 따른 감귤류 과피 추출물의 제조방법은 농축 과정에서 에너지의 소모가 최소화되므로 경제적이고 추출 용매 내지 침전 용매로 물 또는 저급 알코올을 사용하기 때문에 식품 규격에 적합하다. 또한, 본 발명에 따른 감귤류 과피 추출물에 포함된 노빌레틴(nobiletin) 및 탄저레틴(tangeretin)은 유기적인 상승 작용에 의해 알코올, 약물 또는 담즙 분비 정체에 의해 유발되는 간 손상을 효과적으로 억제하거나 개선할 수 있다. 따라서, 본 발명에 따른 감귤류 과피 추출물은 유용한 식의약 소재로 사용될 수 있다.
PCT/KR2016/002606 2015-03-20 2016-03-16 감귤류 과피 추출물의 제조방법 및 간 손상 예방, 개선 또는 치료용 조성물 WO2016153211A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2015-0038844 2015-03-20
KR1020150038844A KR101676751B1 (ko) 2015-03-20 2015-03-20 감귤류 과피 추출물의 제조방법 및 간 손상 예방, 개선 또는 치료용 조성물

Publications (2)

Publication Number Publication Date
WO2016153211A2 WO2016153211A2 (ko) 2016-09-29
WO2016153211A3 true WO2016153211A3 (ko) 2016-11-17

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PCT/KR2016/002606 WO2016153211A2 (ko) 2015-03-20 2016-03-16 감귤류 과피 추출물의 제조방법 및 간 손상 예방, 개선 또는 치료용 조성물

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KR (1) KR101676751B1 (ko)
WO (1) WO2016153211A2 (ko)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102685420B1 (ko) 2016-10-13 2024-07-17 주식회사 비케이바이오 감귤류 가공부산물 효소분해 추출물을 포함하는 숙취해소용 조성물
KR101894491B1 (ko) * 2018-04-30 2018-09-04 주식회사 뉴트라팜텍 지각 초임계 추출물을 유효성분으로 함유하는 기억력 또는 인지 기능 개선용 조성물
KR102201567B1 (ko) * 2018-08-31 2021-01-11 길형준 겔 상의 방향제 조성물의 제조방법
KR102279861B1 (ko) 2019-04-26 2021-07-20 박재규 청귤류로부터 5-o-디메틸노빌레틴의 추출/분리 및 만성 알코올성 지방간 손상보호 조성물
CN111436608A (zh) * 2020-04-21 2020-07-24 梅州金柚康健康科技有限公司 一种改善肝功能损伤的组合物及其应用
KR102595299B1 (ko) * 2020-10-12 2023-10-26 류형준 담즙 분비 촉진 효능이 있는 식품 조성물

Citations (3)

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KR20080015761A (ko) * 2006-08-16 2008-02-20 제주대학교 산학협력단 비만 개선제 조성물
KR20110134742A (ko) * 2010-06-09 2011-12-15 제주대학교 산학협력단 진귤 과피 추출물 또는 이로부터 분리한 폴리메톡시플라본을 유효성분으로 함유하는 염증 예방 또는 치료용 조성물
KR20130035530A (ko) * 2011-09-30 2013-04-09 한국식품연구원 감귤과피 추출물 또는 나리루틴을 유효성분으로 포함하는 간기능 저해 억제용 조성물 및 감귤과피로부터 나리루틴을 추출하는 방법

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KR20130035530A (ko) * 2011-09-30 2013-04-09 한국식품연구원 감귤과피 추출물 또는 나리루틴을 유효성분으로 포함하는 간기능 저해 억제용 조성물 및 감귤과피로부터 나리루틴을 추출하는 방법

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Publication number Publication date
KR20160112683A (ko) 2016-09-28
WO2016153211A2 (ko) 2016-09-29
KR101676751B1 (ko) 2016-11-17

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