WO2016076607A3 - Compound k 성분이 강화된 홍삼농축액을 함유하는 비알코올성 지방간증의 예방 및 치료용 약제학적 조성물 및 건강기능 식품 - Google Patents
Compound k 성분이 강화된 홍삼농축액을 함유하는 비알코올성 지방간증의 예방 및 치료용 약제학적 조성물 및 건강기능 식품 Download PDFInfo
- Publication number
- WO2016076607A3 WO2016076607A3 PCT/KR2015/012064 KR2015012064W WO2016076607A3 WO 2016076607 A3 WO2016076607 A3 WO 2016076607A3 KR 2015012064 W KR2015012064 W KR 2015012064W WO 2016076607 A3 WO2016076607 A3 WO 2016076607A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- preventing
- pharmaceutical composition
- fatty liver
- red ginseng
- alcoholic fatty
- Prior art date
Links
- 235000002789 Panax ginseng Nutrition 0.000 title abstract 2
- 239000012141 concentrate Substances 0.000 title abstract 2
- 208000008338 non-alcoholic fatty liver disease Diseases 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 208000024891 symptom Diseases 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title 1
- 235000013376 functional food Nutrition 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- FVIZARNDLVOMSU-UHFFFAOYSA-N ginsenoside K Natural products C1CC(C2(CCC3C(C)(C)C(O)CCC3(C)C2CC2O)C)(C)C2C1C(C)(CCC=C(C)C)OC1OC(CO)C(O)C(O)C1O FVIZARNDLVOMSU-UHFFFAOYSA-N 0.000 abstract 1
- 235000013402 health food Nutrition 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7032—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyldiacylglycerides, lactobionic acid, gangliosides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/20—Natural extracts
- A23V2250/21—Plant extracts
- A23V2250/2124—Ginseng
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Botany (AREA)
- Mycology (AREA)
- Alternative & Traditional Medicine (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Nutrition Science (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Obesity (AREA)
- Gastroenterology & Hepatology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Medicines Containing Plant Substances (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
본 발명은 효소전환 기술을 이용하여 Compound K 성분이 강화된 홍삼농축액을 유효 성분으로 함유하는 비알코올성 지방간증의 예방 및 치료용 약제학적 조성물 및 건강식품 조성물에 관한 것이다.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR10-2014-0156917 | 2014-11-12 | ||
KR1020140156917A KR20160056554A (ko) | 2014-11-12 | 2014-11-12 | Compound K 성분이 강화된 홍삼농축액을 함유하는 비알코올성 지방간증의 예방 및 치료용 약제학적 조성물 및 건강기능 식품 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2016076607A2 WO2016076607A2 (ko) | 2016-05-19 |
WO2016076607A3 true WO2016076607A3 (ko) | 2016-07-07 |
Family
ID=54540975
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/KR2015/012064 WO2016076607A2 (ko) | 2014-11-12 | 2015-11-10 | Compound k 성분이 강화된 홍삼농축액을 함유하는 비알코올성 지방간증의 예방 및 치료용 약제학적 조성물 및 건강기능 식품 |
Country Status (7)
Country | Link |
---|---|
US (1) | US20160129061A1 (ko) |
EP (1) | EP3020406A1 (ko) |
JP (1) | JP6140789B2 (ko) |
KR (1) | KR20160056554A (ko) |
CN (1) | CN105582033A (ko) |
HK (1) | HK1220123A1 (ko) |
WO (1) | WO2016076607A2 (ko) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102081204B1 (ko) * | 2016-09-08 | 2020-02-25 | (주)아모레퍼시픽 | 탈수소 아비에틱산 및 컴파운드 k를 포함하는 피부 항노화용 조성물 |
KR101978819B1 (ko) * | 2018-11-21 | 2019-05-15 | 주식회사 엠진바이오 | 진세노사이드 화합물 k를 이용한 지방성 간질환 개선용 조성물 |
KR102494672B1 (ko) * | 2019-11-27 | 2023-02-06 | 한희주 | 홍삼, 효소 및 천연물을 이용한 컴파운드 k의 제조방법 |
KR102239804B1 (ko) * | 2020-08-03 | 2021-04-27 | 제너럴바이오(주) | 발효인삼을 함유하는 비알콜성 지방간염 예방 또는 개선용 건강기능성식품 조성물 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20070101441A (ko) * | 2006-04-10 | 2007-10-17 | 주식회사 당바이오텍 | 혼합 생약 추출물을 유효성분으로 함유하는 간 기능 개선용조성물 |
KR100860561B1 (ko) * | 2007-05-02 | 2008-09-26 | 경희대학교 산학협력단 | 컴파운드 k 및 메트포민을 유효성분으로 포함하는당뇨병의 예방 및 치료용 약학적 조성물 |
KR20090022932A (ko) * | 2007-08-31 | 2009-03-04 | 주식회사 케이티앤지 | 화합물 k가 함유된 진세노사이드의 제조방법 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1240390C (zh) * | 2002-01-30 | 2006-02-08 | 株式会社一和 | 生物转化人参组合物及其制备方法 |
KR100497895B1 (ko) * | 2002-12-05 | 2005-06-29 | 홍림통산(주) | 인삼의 유산균 발효물, 그를 함유하는 인삼 요구르트 및그에 이용되는 유산균 균주 |
CN101810659A (zh) * | 2010-05-20 | 2010-08-25 | 吉林省抚松制药股份有限公司 | 紫参总皂苷及其医药用途和制备方法 |
KR101314215B1 (ko) * | 2011-10-07 | 2013-10-14 | 농업회사법인 주식회사 지바이오믹스 | 진세노사이드 알비원에 의한 망막 재생을 통한 눈 기능 저하 및 건성 황반 변성 질환의 예방 및 치료용 조성물 |
KR20130085970A (ko) * | 2012-01-20 | 2013-07-30 | 씨제이제일제당 (주) | 효소전환 및 분획기술을 이용한 사포닌 전환체 화합물 케이-강화된 분획물 및 그 제조방법 |
WO2013109062A1 (ko) * | 2012-01-20 | 2013-07-25 | 씨제이제일제당(주) | 효소전환 및 분획기술을 이용한 사포닌 전환체 화합물 케이-강화된 분획물 및 그 제조방법 |
KR101409761B1 (ko) * | 2012-06-20 | 2014-06-19 | 주식회사한국야쿠르트 | 효소전환과 유산균 발효를 이용한 화합물 k의 함량이 강화된 발효홍삼 농축액의 제조방법 및 그 제조방법에 의해 제조된 발효홍삼 농축액을 유효성분으로 함유하는 제품 |
-
2014
- 2014-11-12 KR KR1020140156917A patent/KR20160056554A/ko not_active Application Discontinuation
-
2015
- 2015-11-09 US US14/936,155 patent/US20160129061A1/en not_active Abandoned
- 2015-11-10 WO PCT/KR2015/012064 patent/WO2016076607A2/ko active Application Filing
- 2015-11-10 CN CN201510763331.5A patent/CN105582033A/zh active Pending
- 2015-11-11 JP JP2015221187A patent/JP6140789B2/ja active Active
- 2015-11-12 EP EP15194312.3A patent/EP3020406A1/en not_active Withdrawn
-
2016
- 2016-07-13 HK HK16108200.1A patent/HK1220123A1/zh unknown
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20070101441A (ko) * | 2006-04-10 | 2007-10-17 | 주식회사 당바이오텍 | 혼합 생약 추출물을 유효성분으로 함유하는 간 기능 개선용조성물 |
KR100860561B1 (ko) * | 2007-05-02 | 2008-09-26 | 경희대학교 산학협력단 | 컴파운드 k 및 메트포민을 유효성분으로 포함하는당뇨병의 예방 및 치료용 약학적 조성물 |
KR20090022932A (ko) * | 2007-08-31 | 2009-03-04 | 주식회사 케이티앤지 | 화합물 k가 함유된 진세노사이드의 제조방법 |
Non-Patent Citations (2)
Title |
---|
HONG, S. H. ET AL.: "Anti-oxidant and Natural Killer Cell Activity of Korean Red Ginseng (Panax Ginseng) and Urushiol (Rhus Vemicifera Stokes) on Non-alcoholic Fatty Liver Disease of Rat.", FOOD AND CHEMICAL TOXICOLOGY, vol. 55, 2013, pages 586 - 591 * |
LEE, H. ET AL.: "Hepatoprotective Effect of Ginsenoside Rb1 and Compound K on Tert-butyl Hydroperoxide Induced Liver Injury.", LIVER INTERNATIONAL, vol. 25, 2005, pages 1069 - 1073 * |
Also Published As
Publication number | Publication date |
---|---|
US20160129061A1 (en) | 2016-05-12 |
EP3020406A1 (en) | 2016-05-18 |
CN105582033A (zh) | 2016-05-18 |
JP2016094414A (ja) | 2016-05-26 |
HK1220123A1 (zh) | 2017-04-28 |
WO2016076607A2 (ko) | 2016-05-19 |
KR20160056554A (ko) | 2016-05-20 |
JP6140789B2 (ja) | 2017-05-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2017095944A8 (en) | Methods and compositions relating to chondrisomes from blood products | |
WO2015171664A3 (en) | Nutrient rich compositions | |
WO2015101957A3 (en) | Inhibitors of glutaminase | |
WO2016094810A3 (en) | Microencapsulated cannabinoid compositions | |
EP3253727A4 (en) | Purified cbd and cbda, and methods, compositions and products employing cbd or cbda | |
PH12014501942A1 (en) | Cereal pieces containing alpha-linolenic acid | |
WO2015142001A3 (ko) | 강심 활성을 갖는 화합물 및 이를 함유하는 심부전 예방 또는 치료용 약학적 조성물 | |
WO2015189346A8 (de) | Neue stoffmischung zur verbesserung des süssgeschmacks enthaltend rubusosid oder alpha-glycosylrubusosid | |
WO2019219774A3 (en) | Eutectic extract formation and purification | |
WO2011090270A3 (ko) | 오스모틴을 포함하는 신경질환의 예방 및 치료용 조성물 | |
EP3102220A4 (en) | Synergistic dietary supplement compositions for the prevention, treatment or control of inflammatory disorders | |
WO2016076607A3 (ko) | Compound k 성분이 강화된 홍삼농축액을 함유하는 비알코올성 지방간증의 예방 및 치료용 약제학적 조성물 및 건강기능 식품 | |
WO2016001761A3 (en) | Lactone-containing compositions for malodor elimination | |
WO2017008136A3 (en) | Flourinated cbd compounds, compositions and uses thereof | |
MX2017016588A (es) | Novedosos glucosidos de triterpeno como edulcorantes o potenciador de edulcorante. | |
WO2012137227A3 (en) | Solid forms of antiretroviral compounds and anti-oxidative acids, processes for preparation and pharmaceutical compositions thereof | |
WO2016112875A3 (zh) | 二联苯衍生物及其应用 | |
WO2016080796A3 (ko) | 세스퀴테르펜 화합물을 포함하는, stat3 매개 질환의 예방 또는 치료용 약학적 조성물 및 이의 용도 | |
WO2016178510A3 (ko) | 진세노사이드 F1 또는 Rg3를 유효성분으로 포함하는 글리벡 내성 백혈병 예방 또는 치료용 약학 조성물 | |
WO2013100718A3 (ko) | 라저스트로에미아 오바리폴리아 추출물 또는 이의 분획물을 유효성분으로 포함하는 염증성 질환 또는 천식의 예방 또는 치료용 약학적 조성물 | |
EP3538121A4 (en) | SYNERGISTIC NUTRITIONAL COMPOSITIONS TO IMPROVE BRAIN HEALTH | |
WO2014194053A3 (en) | Carbohydrate compounds for nutritional and therapeutic use | |
WO2015127320A3 (en) | Single serve beverage compositions | |
WO2016186335A3 (ko) | 상백피추출물과 화살나무추출물을 유효성분으로 포함하는 충치 예방 및 치료용 구강조성물 | |
CA3041260C (en) | Allulose-containing composition for promoting excretion of vegetable lipids from the body |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 15858882 Country of ref document: EP Kind code of ref document: A2 |
|
NENP | Non-entry into the national phase |
Ref country code: DE |
|
32PN | Ep: public notification in the ep bulletin as address of the adressee cannot be established |
Free format text: NOTING OF LOSS OF RIGHTS PURSUANT TO RULE 112(1) EPC (EPO FORM 105A DATED 21/08/2017) |
|
122 | Ep: pct application non-entry in european phase |
Ref document number: 15858882 Country of ref document: EP Kind code of ref document: A2 |