WO2016058512A8 - 马拉巴石斑鱼Piscidin的改造体抗菌肽及其应用 - Google Patents

马拉巴石斑鱼Piscidin的改造体抗菌肽及其应用 Download PDF

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Publication number
WO2016058512A8
WO2016058512A8 PCT/CN2015/091800 CN2015091800W WO2016058512A8 WO 2016058512 A8 WO2016058512 A8 WO 2016058512A8 CN 2015091800 W CN2015091800 W CN 2015091800W WO 2016058512 A8 WO2016058512 A8 WO 2016058512A8
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WO
WIPO (PCT)
Prior art keywords
transformed
antibacterial peptide
piscidin
applications
epinephelus malabaricus
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Application number
PCT/CN2015/091800
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English (en)
French (fr)
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WO2016058512A1 (zh
Inventor
邓利
原为明
胡章立
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深圳大学
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Application filed by 深圳大学 filed Critical 深圳大学
Priority to CN201580011347.9A priority Critical patent/CN106459163B/zh
Publication of WO2016058512A1 publication Critical patent/WO2016058512A1/zh
Publication of WO2016058512A8 publication Critical patent/WO2016058512A8/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

提供一种马拉巴石斑鱼piscidin的改造体抗菌肽、编码其的基因以及含有上述编码改造体抗菌肽基因的重组表达载体。
PCT/CN2015/091800 2014-10-15 2015-10-13 马拉巴石斑鱼Piscidin的改造体抗菌肽及其应用 WO2016058512A1 (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201580011347.9A CN106459163B (zh) 2014-10-15 2015-10-13 马拉巴石斑鱼Piscidin的改造体抗菌肽及其应用

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201410545484.8 2014-10-15
CN201410545484.8A CN105566483A (zh) 2014-10-15 2014-10-15 马拉巴石斑鱼Piscidin的改造体抗菌肽及其应用

Publications (2)

Publication Number Publication Date
WO2016058512A1 WO2016058512A1 (zh) 2016-04-21
WO2016058512A8 true WO2016058512A8 (zh) 2016-12-29

Family

ID=55746132

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2015/091800 WO2016058512A1 (zh) 2014-10-15 2015-10-13 马拉巴石斑鱼Piscidin的改造体抗菌肽及其应用

Country Status (2)

Country Link
CN (2) CN105566483A (zh)
WO (1) WO2016058512A1 (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106367429A (zh) * 2016-08-30 2017-02-01 福建福鼎海鸥水产食品有限公司 串联piscidin抗菌肽PSP的构建及分泌表达
CN107058432B (zh) * 2017-03-29 2020-08-14 深圳大学 一种非甲醇诱导生产抗菌肽的方法
CN108949577A (zh) * 2018-10-30 2018-12-07 中国科学院烟台海岸带研究所 一种新型饵料微藻及其制备和应用
CN110305890A (zh) * 2019-07-02 2019-10-08 河南城建学院 一种新型5种抗菌肽串联表达重组工程菌构建方法及其应用
CN111471094B (zh) * 2020-04-30 2022-04-12 大连理工大学 一种抗微生物肽MSPiscidin-2、其编码基因及用途
CN111574610B (zh) * 2020-06-08 2023-05-02 宁德市富发水产有限公司 大黄鱼抗菌肽piscidin 5-like type 4及其制备方法与应用
CN113980111B (zh) * 2021-04-15 2023-08-22 青岛科技大学 一种从文昌鱼中筛选的具有抗菌活性的多肽
CN113599497B (zh) * 2021-08-03 2023-10-20 华南农业大学 斜带石斑鱼piscidin1及其合成多肽在制备抗病毒或抗细菌药物中的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103333898B (zh) * 2013-06-14 2015-01-28 深圳大学 一种表达石斑鱼抗菌肽piscidin的转基因莱茵衣藻的构建与应用

Also Published As

Publication number Publication date
CN105566483A (zh) 2016-05-11
CN106459163A (zh) 2017-02-22
WO2016058512A1 (zh) 2016-04-21
CN106459163B (zh) 2019-07-12

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