WO2016051304A1 - Appareil et procédé de commande de l'odeur de l'haleine combinant poils optimisés et mouvement mécanique - Google Patents

Appareil et procédé de commande de l'odeur de l'haleine combinant poils optimisés et mouvement mécanique Download PDF

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Publication number
WO2016051304A1
WO2016051304A1 PCT/IB2015/057188 IB2015057188W WO2016051304A1 WO 2016051304 A1 WO2016051304 A1 WO 2016051304A1 IB 2015057188 W IB2015057188 W IB 2015057188W WO 2016051304 A1 WO2016051304 A1 WO 2016051304A1
Authority
WO
WIPO (PCT)
Prior art keywords
bristles
tongue
head
cleaning device
body portion
Prior art date
Application number
PCT/IB2015/057188
Other languages
English (en)
Inventor
Jayprakash PATEL
Paola Rocio GOMEZ PEREIRA
Pieter HORSTMAN
Original Assignee
Koninklijke Philips N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklijke Philips N.V. filed Critical Koninklijke Philips N.V.
Publication of WO2016051304A1 publication Critical patent/WO2016051304A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A46—BRUSHWARE
    • A46B—BRUSHES
    • A46B15/00—Other brushes; Brushes with additional arrangements
    • A46B15/0055—Brushes combined with other articles normally separate from the brushing process, e.g. combs, razors, mirrors
    • A46B15/0081—Brushes with a scraper, e.g. tongue scraper
    • A—HUMAN NECESSITIES
    • A46—BRUSHWARE
    • A46B—BRUSHES
    • A46B13/00—Brushes with driven brush bodies or carriers
    • A46B13/02—Brushes with driven brush bodies or carriers power-driven carriers
    • A46B13/023—Brushes with driven brush bodies or carriers power-driven carriers with means for inducing vibration to the bristles
    • A—HUMAN NECESSITIES
    • A46—BRUSHWARE
    • A46D—MANUFACTURE OF BRUSHES
    • A46D1/00—Bristles; Selection of materials for bristles
    • A46D1/02—Bristles details
    • A46D1/0276—Bristles having pointed ends
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/24—Surgical instruments, devices or methods, e.g. tourniquets for use in the oral cavity, larynx, bronchial passages or nose; Tongue scrapers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/24—Surgical instruments, devices or methods, e.g. tourniquets for use in the oral cavity, larynx, bronchial passages or nose; Tongue scrapers
    • A61B17/244—Surgical instruments, devices or methods, e.g. tourniquets for use in the oral cavity, larynx, bronchial passages or nose; Tongue scrapers for cleaning of the tongue
    • A—HUMAN NECESSITIES
    • A46—BRUSHWARE
    • A46B—BRUSHES
    • A46B13/00—Brushes with driven brush bodies or carriers
    • A46B13/02—Brushes with driven brush bodies or carriers power-driven carriers
    • A—HUMAN NECESSITIES
    • A46—BRUSHWARE
    • A46B—BRUSHES
    • A46B9/00—Arrangements of the bristles in the brush body
    • A46B9/02—Position or arrangement of bristles in relation to surface of the brush body, e.g. inclined, in rows, in groups
    • A46B9/04—Arranged like in or for toothbrushes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C17/00—Devices for cleaning, polishing, rinsing or drying teeth, teeth cavities or prostheses; Saliva removers; Dental appliances for receiving spittle
    • A61C17/16—Power-driven cleaning or polishing devices

Definitions

  • the present disclosure is directed generally to devices for use in cleaning the surface of the tongue utilizing a synergistic combination of optimized bristles and mechanical motion.
  • Halitosis also known as bad breath, is a common complaint among the adult population, affecting as much as 20-30% or more of adults.
  • the tongue is a hospitable location for a wide variety of bacterial species to colonize and form a thick, nearly impenetrable biofilm.
  • This biofilm generates a variety of compounds, such as skatoles and volatile sulfur, which contribute to halitosis.
  • Treatment of halitosis typically consists of cleaning the tongue surface using a tongue scraper and/or mouthwash.
  • the tongue scraper is utilized in an attempt to physically scrape the bacteria off the surface, although this method is largely unsuccessful. Too much pressure during scraping can cause damage to the tongue microstructure.
  • the bacteria, especially in biofilm form remain firmly entrenched in the spaces between neighboring papillae (the protrusions on the surface of the tongue) despite the application of force during scraping.
  • tongue scrapers Instead of removing the biofilm, tongue scrapers often flatten the papillae and trap the biofilm in the spaces, which can then quickly regrow. Accordingly, tongue scrapers typically only reduce halitosis conditions for very short period of time, ranging from minutes to at most several hours.
  • Another method of treatment for halitosis consists of using mouthwash to dislodge bacteria or, in the case of antibacterial mouthwashes, kill the bacteria inhabiting the surface of the tongue.
  • gargling with mouthwash can temporarily cover the symptoms of halitosis by introducing a strong odorant, mouthwash is ineffective against halitosis after any significant period of time.
  • the biofilms found on the surface of the tongue have a coating that is largely impervious to the chemicals or antibacterial agents found within the mouthwash, even if the use of mouthwash is combined with physical scraping.
  • the present disclosure is directed to inventive methods and devices for removing the bacterial biofilm coating the surface of the tongue using a synergistic combination of optimized bristles and mechanical motion.
  • Various embodiments and implementations herein are directed to a tongue cleaning method and device in which a tongue cleaner mechanically vibrates tongue- cleaning bristles which are optimized to attack the bacterial biofilm, alone or in combination with appropriate mouth cleaning chemistry and/or antibacterial agents.
  • the device is a mechanical tongue cleaner capable of generating vibrations and transmitting those vibrations to a plurality of optimized bristles that engage the surface of the tongue.
  • the optimized bristles are composed of a soft elastomeric polymer, and are both pointed and intentionally spaced at a predetermined density to deliver the pointed ends of the optimized bristles to the spaces between the papillae of the tongue surface.
  • the mechanical vibrations generated by the tongue cleaner allow the pointed ends of the bristles to attack and break apart the bacterial biofilm located between the papillae.
  • the mechanical tongue cleaner combines the vibration of optimized bristles with chemistry to introduce an antibacterial agent and/or cleaning agent to the bacterial biofilm. While the pointed bristles are attacking and dislodging the bacteria located between neighboring papillae the antibacterial agent and/or cleaning agent can be delivered, thereby introducing the agent deeper into the biofilm than is possible using existing methods.
  • a tongue cleaning device is provided.
  • the tongue cleaning device includes a body portion having a vibration generator; an elongated head extending from the body portion, the head comprising a bristle face proximate its distal end, where the head is configured to vibrate relative to the body portion; a plurality of bristles connected at one end to the bristle face, and each having a pointed end extending along an axis perpendicular to the head's axis of elongation, the plurality of soft bristles arranged in a density configured to engage the surface of the tongue; wherein the vibration generator generates vibrations and transmits the vibrations to the head such that the pointed ends of the plurality of bristles vibrate.
  • each of the bristles is cone-shaped with an aspect ratio of 1 : 1.
  • each of the plurality of bristles has a durometer hardness measurement of between approximately 40 and 70 on the Shore A scale.
  • each of the plurality of bristles are approximately 250 to 3000 microns in length, and more particularly, approximately 500 - 1500 microns in length, and optimally approximately 1000 microns in length.
  • a method for cleaning the surface of the tongue includes the steps of: providing a tongue cleaning device having: (i) a body portion with a vibration generator; (ii) an elongated head extending from the body portion and having a bristle face proximate its distal end, where the head is configured to vibrate relative to the body portion; and (iii) a plurality of bristles each connected at one end to the bristle face and each having a pointed end extending along an axis perpendicular to the head's axis of elongation; vibrating, using the vibration generator, the pointed ends of the plurality of bristles; and cleaning the surface of the tongue with the vibrating plurality of bristles.
  • each of the bristles is cone-shaped with an aspect ratio of 1 : 1.
  • each of the plurality of bristles has a durometer of between approximately 40 and 70 on the Shore A scale.
  • the method also includes the step of introducing an additive to the surface, such as ingesting the agent just prior to cleaning, or spraying on the surface of the tongue just prior to cleaning.
  • the additive is a cleaning agent and/or an antibacterial agent.
  • the bristles are vibrated at approximately 75 Hz or greater.
  • each of the plurality of bristles are approximately 250 to 3000 microns in length.
  • FIG. 1 is a schematic representation of a tongue cleaning device in accordance with an embodiment.
  • FIG. 2 is a schematic representation of the head member of a tongue cleaning device in accordance with an embodiment.
  • FIGS. 3 and 4 are schematic representations of optimized tongue cleaning bristles in accordance with an embodiment.
  • FIG. 5 is a graph of biofilm removal by bristles of different lengths and hardness in accordance with an embodiment.
  • FIG. 6 is a graph of volatile sulfur compound production following treatment with a traditional tongue scraper and additive versus treatment with a tongue cleaning device and additive in accordance with an embodiment.
  • FIG. 7 is a flow chart of a method for cleaning the tongue using a mechanical tongue cleaning device with optimized bristles in accordance with an embodiment.
  • FIG. 8 is a graph of organoleptic scores following treatment with water versus the mechanical tongue cleaning device with optimized bristles, with and without additive, in accordance with an embodiment.
  • the present disclosure describes various embodiments of devices, systems, and methods that use mechanical motion to attack the bacterial biofilm coating the surface of the tongue. More generally, Applicants have recognized and appreciated that it would be beneficial to treat halitosis caused by bacterial biofilms coating the surface of the tongue. It was discovered that there is an unexpected synergistic effect resulting from the combination of mechanical motion and bristles having optimized shape and density. For example, effective cleaning of the tongue is substantially improved by a device and method in which a mechanical tongue cleaner generates vibrations and transmits those vibrations to a plurality of optimized bristles that engage the surface of the tongue.
  • various embodiments and implementations are directed to devices and methods in which a mechanical tongue cleaner generates vibrations and transmits those vibrations to a plurality of optimized bristles composed of a soft polymer.
  • the optimized bristles are pointed and intentionally spaced at a predetermined density to deliver the pointed ends of the optimized bristles to the spaces between the papillae of the tongue surface.
  • the mechanical vibrations generated by the tongue cleaner allow the pointed ends of the bristles to attack and break apart the bacterial biofilm located between the papillae.
  • the device combines the vibration of optimized bristles with a mouthwash, antibacterial agent, and/or cleaning agent that is introduced deep into the biofilm by the vibrating bristles.
  • a tongue cleaning device 10 that includes a body portion 12 and a head member 14 mounted on the body portion.
  • Head member 14 includes at its end remote from the body portion a brush head 16.
  • Brush head 16 includes a bristle face 18 proximate the distal end 40 of the head member, and the bristle face provides a plurality of bristles 20.
  • the bristles extend along an axis substantially perpendicular to the head's axis of elongation.
  • Head member 14, brush head 16, and/or bristle face 18 are mounted so as to be able to vibrate relative to the body portion 12.
  • the vibrations can be any of a variety of different vibrations, including up and down, side to side, and in a circle, among others.
  • head member 14 is mounted to the body so as to be able to vibrate relative to body portion 12, or, as another example, brush head 16 is mounted to head member 14 so as to be able to vibrate relative to body portion 12.
  • the bristles are vibrated at a first frequency 38 that is equal to or greater than approximately 75 Hz, but many other frequencies, patterns, and vibrations are possible.
  • the head member 14 can be fixedly mounted onto body portion 12, or it may alternatively be detachably mounted so that head member 14 can be replaced with a new one when the bristles 20 or another component of the device are worn out and require replacement.
  • Body portion 12 includes a vibration generator 22 for generating vibrations and a transmission component 24 for transmitting the generated vibrations to head member 14.
  • vibration generator 22 can comprise a motor or electromagnet(s) that generate vibrations of the transmission component 24, which are subsequently transmitted to the head member 14.
  • Vibration generator 22 may alternatively comprise any other known type of vibration mechanism capable of generating high frequency vibrations.
  • the vibration generator 22 can include vibration electronics such as a power supply, an oscillator, and one or more electromagnets, among other components.
  • the power supply comprises one or more rechargeable batteries, not shown in FIG. 1 , which can be electrically charged in a charging holder in which tongue cleaning device 10 is placed when not in use.
  • body portion 12 is further provided with an on/off button 26 to activate and deactivate vibration generator 22. It is anticipated that head member 14 can be affixed to and used with a body portion 12 of a powered oral care device, such as a power toothbrush, varieties of which are commonly known in the industry.
  • a head member 14 is provided, separate from body portion 12.
  • the head member includes at its distal end 40 remote from the body portion a brush head 16 with a bristle face 18 having multiple bristles 20.
  • the length of head member 14 is configured to be suitable for cleaning both the anterior and posterior surfaces of a human tongue.
  • bristles 20 are optimized to a density (42) that maximizes the effect of the pointed tips 30 of the bristles on the spaces between papillae on the human tongue.
  • the density (42) of the optimized bristles varies and can include density 42a, density 42b, density 42c, and density 42d, for example, which depend at least in part on the shape and size of the bristles.
  • a variety of bristles 20 are provided.
  • bristles 20 are cone-shaped with a pointed tip 30.
  • the cone-shaped bristles have a height H and a base width of W.
  • Width W decreases continuously along height H, ranging from a maximum value W to a minimum value at pointed tip 30. Since the bases of neighboring cone-shaped bristles cannot overlap, width W also defines a maximum density (42) of these bristles. As a result, the density of the plurality of bristles 20 on the bristle face 18 can be varied by spacing apart the bristles, or by increasing or decreasing the value of width W of the base of the cone-shaped bristles. According to an embodiment, each of cone-shaped bristles 20 have an aspect ratio of 1 : 1 , meaning that the values of width W and height H are approximately equal. According to an embodiment, bristles 20 are approximately 250 to 3000 microns in length.
  • width W will similarly be approximately 250 microns.
  • the bristles 20 are cone- shaped bristles of approximately 1000 microns in length, where height H and width W (at the cone base, for example) are approximately 1000 microns.
  • the cone-shaped bristles can be manufactured or arranged in a density of approximately 100 bristles per cm .
  • Bristles 20 may alternatively comprise another shape optimized to reach between the papillae on the human tongue without damaging or flattening the microstructure of the tongue. It is also anticipated that an arrangement of a brush head 16 having varying bristles of differing sizes and densities can exist.
  • Bristles 20 are preferably composed of a material suitable for attacking a biofilm or other bacterial coating on the surface of the tongue without significantly damaging the microstructure of the tongue.
  • bristles 20 can be composed of a polymer such as polydimethylsiloxane (PDMS), Evoprene ® , or similar thermoplastic or cast elastomers, other silicones, or any other known type of polymer suitable for the mouth.
  • PDMS polydimethylsiloxane
  • Evoprene ® Evoprene ®
  • the durometer, or measure of hardness, of the polymer can vary depending on a variety of factors. For example, according to an embodiment, a harder bristle may be more efficient at removing bacteria from the surface of the tongue. Referring to FIG.
  • 5 is a graph of the effectiveness of bristles having different hardness (or "shore") values.
  • bristles having durometer or shore hardness measurements of 5, 40, and 70 on the Shore A scale were used in conjunction with sonic vibrations at 250 Hz to determine the ability of the bristles to remove a biofilm compared to a control of no treatment at all.
  • Bristles of each durometer were used at varying lengths of 500 microns, 1000 microns, and 2000 microns. While some ability change in the cleaning was seen at different bristle lengths, a durometer measurement of greater than 5, particularly between 40 and 70, had an unexpected effect on the removal of the biofilm.
  • an additive 36 known or otherwise configured to attack bacteria such as a biofilm on the surface of the tongue can be used in conjunction with a tongue cleaning device 10.
  • additive 36 can be a commercially-available mouthwash, and can optionally include an antibacterial agent.
  • an antibacterial agent for example, zinc ions, chlorhexidine (CHX), and cetylpyridinium (CPC) inhibit production of volatile sulfur compounds, which are created by the bacterial biofilm lining the surface of the tongue and contribute to halitosis.
  • the additive can be or include alcohol, fluoride, hydrogen peroxide, phenol, sanguinarine, sodium bicarbonate, sodium chloride, sodium lauryl sulfate, tetracycline, and/or triclosan, among other additives.
  • a mouthwash with an antibacterial agent suitable to serve as additive 36 is BreathRX.
  • a tongue cleaning device 10 can be provided that includes further includes a fluid container which can deliver additive contained therein directly through the brush head 16, such as the oral care assembly device disclosed in U.S. Provisional Patent Application Number 62/056,662, filed contemporaneously herewith on September 29, 2014.
  • mouthwashes are highly effective at killing bacteria, many fail to provide breath odor protection for more than a few hours.
  • the biofilm on the surface of the tongue forms a dense, liquid-repellent layer and is therefore resistant to antibacterial attack.
  • biofilm on the tongue may be as much as 500 micrometers thick, mouthwashes are typically only able to penetrate up to 20 micrometers.
  • a mouthwash may temporarily inhibit production of volatile sulfur compounds, the biofilm is not significantly damaged by the mouthwash and quickly grows back to normal levels. Experiments showed that even if combined with traditional cleaners that scrape the surface of the tongue, mouthwash does not exhibit an increased ability to inhibit biofilm growth and production of volatile sulfur compounds.
  • use of an additive 36 with a tongue cleaning device 10 having a plurality of optimized vibrating bristles 20 in accordance with an embodiment displays an unexpected synergistic effect on biofilm re-growth and the production of volatile sulfur compounds.
  • Volatile sulfur compounds a symptom of biofilm, recover quickly following treatment with a traditional tongue scraper and additive, returning to 80% of the baseline within 3 hours of treatment.
  • tongue cleaning device 10 when tongue cleaning device 10 generates vibrations of the optimized bristles 20, it delivers the additive 36 significantly deeper into the bio film by acting between the papillae, in addition to removal of the biofilm.
  • the optimized density, shape, and/or hardness of the plurality of bristles likely plays a role in the unexpected synergistic effect demonstrated in FIGS. 5, 6, and similar experiments.
  • FIG. 8 a graph of organoleptic scores following treatment with water versus the mechanical tongue cleaning device with optimized bristles, with and without additive, is provided.
  • Use of an additive 36 with a tongue cleaning device 10 having a plurality of optimized vibrating bristles 20 in accordance with an embodiment displays an unexpected synergistic effect on biofilm re-growth and the production of volatile sulfur compounds.
  • the graph in FIG. 8 represents experimental data in which subjects performed four different treatments: (i) water alone; (ii) additive (such as BreathRx antibacterial mouthwash spray); (iii) tongue cleaning device 10 with water; or (iv) tongue cleaning device 10 with additive, in which .
  • a flow chart illustrating a method 700 for cleaning the surface of the tongue in accordance with an embodiment of the invention is disclosed.
  • a tongue cleaning device 10 is provided.
  • Tongue cleaning device 10 may be any of the embodiments described herein or otherwise envisioned, and can include any of the components of the units described in conjunction with FIGS. 1-4.
  • tongue cleaning device 10 can include a body portion 12 and a head member 14 mounted on the body portion with a brush head 16, bristle face 18, and plurality of bristles 20.
  • an additive 36 is introduced to the surface of the tongue during cleaning.
  • the additive may be any of the additives disclosed or otherwise envisioned herein, and may include a cleaning agent and/or an antibacterial agent.
  • the additive may be added at any point in the method. For example, the user can ingest into the mouth (but not swallow) the additive, such as a mouthwash, just prior to activating and using the tongue cleaning device. The additive will then be present in the mouth as the tongue cleaning device is used to clean the tongue. Alternatively, the additive may be introduced during the cleaning cycle.
  • step 730 the vibration generator of tongue cleaning device 10 is activated and the vibrations are transmitted to head member 14 and the plurality of bristles 20, causing each of the plurality of bristles to vibrate.
  • the vibrations can be up and down, side to side, and/or rotating, among other variations.
  • the bristles are vibrated at or greater than approximately 75 Hz, but many other frequencies, patterns, and vibrations are possible.
  • the vibration generator of tongue cleaning device 10 can be activated for example, by the on/off button 26 on body portion 12, or any other known method or mechanism for activating or deactivating vibration generator 22.
  • the vibrating plurality of bristles is used to clean the surface of the tongue.
  • the user can move tongue cleaning device 10 around, thereby causing the handle and bristles to move while vibrating, or the user can keep the tongue cleaning device 10 substantially still and let the vibrating bristles penetrate the biofilm by vibrations alone.
  • a specific cleaning cycle shows an unexpected improvement in cleaning the tongue and inhibiting the recovery of volatile sulfur compounds.
  • Cleaning the surface of the tongue three times in a row significantly improves the inhibition of volatile sulfur compounds compared to other cycles such as twice in a row. For example, cleaning three times each for approximately 10 to 20 seconds is more effective than cleaning twice in a row, even if the cleaning sessions are longer (20 seconds, 30 seconds, or longer). Thus, it is repetition rather than length of time cleaning affecting the effectiveness of cleaning.
  • this unexpected phenomenon including the breakup of the biofilm during the brief interludes, among other explanations.
  • tongue cleaning device 10 can include a timer or other mechanism that assists the user in counting the number of repetitions and the length of time of each repetition.
  • tongue cleaning device 10 includes a counter to count up to three repetitions, and a timer to count down at least 10 to 20 seconds.
  • tongue cleaning device 10 can come with instructions or other directions to induce the user to clean the surface of the tongue at least three times in a row, each for approximately 10 to 20 seconds.
  • the phrase "at least one,” in reference to a list of one or more elements, should be understood to mean at least one element selected from any one or more of the elements in the list of elements, but not necessarily including at least one of each and every element specifically listed within the list of elements and not excluding any combinations of elements in the list of elements.
  • This definition also allows that elements may optionally be present other than the elements specifically identified within the list of elements to which the phrase "at least one" refers, whether related or unrelated to those elements specifically identified.
  • inventive embodiments are presented by way of example only and that, within the scope of the appended claims and equivalents thereto, inventive embodiments may be practiced otherwise than as specifically described and claimed.
  • inventive embodiments of the present disclosure are directed to each individual feature, system, article, material, kit, and/or method described herein.

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  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Otolaryngology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dentistry (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Brushes (AREA)

Abstract

L'invention concerne un dispositif (10) et un procédé (700) de nettoyage de la langue.Le dispositif de nettoyage de la langue comprend une partie corps (12) dotée d'un générateur de vibrations (22), et un élément tête allongée (14) s'étendant depuis la partie corps. L'élément tête comprend une face (18) de poils à proximité de l'extrémité distale (40), où la tête est conçue pour vibrer par rapport à la partie corps. La face de poils comprend une pluralité de poils (20) reliés par une première extrémité à la face de poils, ayant chacun une extrémité pointue (30) s'étendant le long d'un axe perpendiculaire à l'axe d'allongement de la tête, et configurée selon une densité (42) optimisée pour s'appliquer sur la surface de la langue. Le générateur de vibrations crée des vibrations d'une première fréquence (38) qui sont transmises à la tête de telle sorte que les extrémités pointues de la pluralité de poils vibrent à la première fréquence tout en s'appliquent sur la surface de la langue.
PCT/IB2015/057188 2014-09-29 2015-09-18 Appareil et procédé de commande de l'odeur de l'haleine combinant poils optimisés et mouvement mécanique WO2016051304A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462056755P 2014-09-29 2014-09-29
US62/056,755 2014-09-29

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Publication Number Publication Date
WO2016051304A1 true WO2016051304A1 (fr) 2016-04-07

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023000634A1 (fr) * 2021-07-20 2023-01-26 深圳罗马仕科技有限公司 Unité de nettoyage et hydropulseur

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007140959A1 (fr) * 2006-06-02 2007-12-13 Braun Gmbh appareil pour l'hygiÈne buccale
US20120174328A1 (en) * 2002-08-09 2012-07-12 Colgate-Palmolive Company Oral care implement having flexibly supported cleaning elements extending in opposite directions
US20120180806A1 (en) * 2011-01-13 2012-07-19 Orabrush Inc. Method of using and composition for a foaming oral cleaner

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120174328A1 (en) * 2002-08-09 2012-07-12 Colgate-Palmolive Company Oral care implement having flexibly supported cleaning elements extending in opposite directions
WO2007140959A1 (fr) * 2006-06-02 2007-12-13 Braun Gmbh appareil pour l'hygiÈne buccale
US20120180806A1 (en) * 2011-01-13 2012-07-19 Orabrush Inc. Method of using and composition for a foaming oral cleaner

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023000634A1 (fr) * 2021-07-20 2023-01-26 深圳罗马仕科技有限公司 Unité de nettoyage et hydropulseur

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