WO2016006975A3 - Nouveaux dérivés imidazotriazinone ou imidazopyrazinone et leur utilisation - Google Patents

Nouveaux dérivés imidazotriazinone ou imidazopyrazinone et leur utilisation Download PDF

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Publication number
WO2016006975A3
WO2016006975A3 PCT/KR2015/007220 KR2015007220W WO2016006975A3 WO 2016006975 A3 WO2016006975 A3 WO 2016006975A3 KR 2015007220 W KR2015007220 W KR 2015007220W WO 2016006975 A3 WO2016006975 A3 WO 2016006975A3
Authority
WO
WIPO (PCT)
Prior art keywords
imidazotriazinone
novel
imidazopyrazinone
derivatives
imidazopyrazinone derivatives
Prior art date
Application number
PCT/KR2015/007220
Other languages
English (en)
Other versions
WO2016006975A2 (fr
Inventor
Jung Nyoung Heo
Hwan Jung LIM
Kwang Rok Kim
Kyung Jin Kim
Uk Il Kim
Hyung Tae Bang
Ji Hye Yoon
Original Assignee
St Pharm Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1020150068368A external-priority patent/KR20160007347A/ko
Application filed by St Pharm Co., Ltd. filed Critical St Pharm Co., Ltd.
Priority to EP15818456.4A priority Critical patent/EP3166946A4/fr
Priority to US15/325,692 priority patent/US10179785B2/en
Publication of WO2016006975A2 publication Critical patent/WO2016006975A2/fr
Publication of WO2016006975A3 publication Critical patent/WO2016006975A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Abstract

La présente invention concerne un nouveau dérivé imidazotriazinone ou imidazopyrazinone, un tautomère de celui-ci, un stéréoisomère de celui-ci et leur mélange, ou un sel pharmaceutiquement acceptable de celui-ci; et une composition pharmaceutique pour la prévention ou le traitement d'une maladie liée à la tankyrase, qui contient les dérivés selon l'invention en tant qu'ingrédient actif.
PCT/KR2015/007220 2014-07-11 2015-07-10 Nouveaux dérivés imidazotriazinone ou imidazopyrazinone et leur utilisation WO2016006975A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP15818456.4A EP3166946A4 (fr) 2014-07-11 2015-07-10 Nouveaux dérivés imidazotriazinone ou imidazopyrazinone et leur utilisation
US15/325,692 US10179785B2 (en) 2014-07-11 2015-07-10 Imidazotriazinone or imidazopyrazinone derivatives, and use thereof

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR10-2014-0087799 2014-07-11
KR20140087799 2014-07-11
KR10-2015-0068368 2015-05-15
KR1020150068368A KR20160007347A (ko) 2014-07-11 2015-05-15 신규한 이미다조트리아지논 또는 이미다조피라지논 유도체, 및 이들의 용도

Publications (2)

Publication Number Publication Date
WO2016006975A2 WO2016006975A2 (fr) 2016-01-14
WO2016006975A3 true WO2016006975A3 (fr) 2016-07-21

Family

ID=55065061

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2015/007220 WO2016006975A2 (fr) 2014-07-11 2015-07-10 Nouveaux dérivés imidazotriazinone ou imidazopyrazinone et leur utilisation

Country Status (1)

Country Link
WO (1) WO2016006975A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180044343A1 (en) * 2015-03-16 2018-02-15 Sumitomo Dainippon Pharma Co., Ltd. Bicyclic imidazolo derivative
CN107286169B (zh) * 2016-04-05 2020-11-24 北京四环制药有限公司 端锚聚合酶抑制剂
CN106496056B (zh) * 2016-10-18 2018-03-02 中国人民解放军63975部队 一种芳基酰胺类化合物的合成方法
EP3733206A4 (fr) * 2017-12-27 2021-12-01 Japanese Foundation For Cancer Research Agent anticancéreux

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013110768A1 (fr) * 2012-01-26 2013-08-01 H. Lundbeck A/S Inhibiteurs de pde9 comprenant un squelette imidazotriazinone
WO2013143663A1 (fr) * 2012-03-28 2013-10-03 Merck Patent Gmbh Dérivés bicycliques de pyrazinone
US20130331375A1 (en) * 2012-06-07 2013-12-12 Genentech, Inc. Pyrrolopyrimidone and pyrrolopyridone inhibitors of tankyrase
US20130345215A1 (en) * 2012-06-07 2013-12-26 Genentech, Inc. Pyrazolopyrimidone and pyrazolopyridone inhibitors of tankyrase
US20130345226A1 (en) * 2012-06-20 2013-12-26 Hoffmann-La Roche Inc. Pyrrolopyrazone inhibitors of tankyrase
KR20140051944A (ko) * 2011-07-13 2014-05-02 노파르티스 아게 탄키라제 억제제로서 사용하기 위한 4-피페리디닐 화합물

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20140051944A (ko) * 2011-07-13 2014-05-02 노파르티스 아게 탄키라제 억제제로서 사용하기 위한 4-피페리디닐 화합물
WO2013110768A1 (fr) * 2012-01-26 2013-08-01 H. Lundbeck A/S Inhibiteurs de pde9 comprenant un squelette imidazotriazinone
WO2013143663A1 (fr) * 2012-03-28 2013-10-03 Merck Patent Gmbh Dérivés bicycliques de pyrazinone
US20130331375A1 (en) * 2012-06-07 2013-12-12 Genentech, Inc. Pyrrolopyrimidone and pyrrolopyridone inhibitors of tankyrase
US20130345215A1 (en) * 2012-06-07 2013-12-26 Genentech, Inc. Pyrazolopyrimidone and pyrazolopyridone inhibitors of tankyrase
US20130345226A1 (en) * 2012-06-20 2013-12-26 Hoffmann-La Roche Inc. Pyrrolopyrazone inhibitors of tankyrase

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP3166946A4 *

Also Published As

Publication number Publication date
WO2016006975A2 (fr) 2016-01-14

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