WO2015130184A1 - Stent for catching and breaking up thromboemboli - Google Patents
Stent for catching and breaking up thromboemboli Download PDFInfo
- Publication number
- WO2015130184A1 WO2015130184A1 PCT/RS2015/000006 RS2015000006W WO2015130184A1 WO 2015130184 A1 WO2015130184 A1 WO 2015130184A1 RS 2015000006 W RS2015000006 W RS 2015000006W WO 2015130184 A1 WO2015130184 A1 WO 2015130184A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- microchip
- stent
- impulse
- thromboemboli
- crystal
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/01—Filters implantable into blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
- A61B5/4839—Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/02007—Evaluating blood vessel condition, e.g. elasticity, compliance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
- A61F2230/0004—Rounded shapes, e.g. with rounded corners
- A61F2230/0006—Rounded shapes, e.g. with rounded corners circular
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0001—Means for transferring electromagnetic energy to implants
- A61F2250/0002—Means for transferring electromagnetic energy to implants for data transfer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
- A61F2250/0068—Means for introducing or releasing pharmaceutical products into the body the pharmaceutical product being in a reservoir
Definitions
- This invention relates to medical devices, or filters which prevent clogging of blood vessels by thromboemboli.
- the technical problem which is solved with this invention is how to construct a stent which will block the passage and dissolve thrombi on blood vessels which lead to brain, Jungs, heart, while the stent has a transversely positioned mesh which blocks the passage of thrombi, whereby the medicaments for thrombus dissolution is being inserted, which is activated with via piezoelectric impulse caused by the thrombus impacting the mesh.
- the thrombi problem is solved differently, that is, via surgical interventions of blood clot removal and use of medicaments for their breakage, which are injected into the blood vessels after their detection or precautionary, and thus diffused throughout the bloodstream, which requires a larger medicament amount compared to if it were injected close to the thrombus.
- Preventive methods also require constant use of blood dilution medicines.
- the essence of the invention consists of the following:
- nitinol an alloy of nickel and titanium, which has the property of memorizing its original shape
- crystal or ceramic tablets in which piezoelectricity is induced due to micro-deformations on the meshes.
- the base of the stent made from electrically insulating plastic, with a cavity for the medicament, which is partly covered with a crystal or ceramic tablet, which can stretch via a piezoelectric impulse, created by the impact of the thrombus on the mesh (Lippmann effect), which expels a droplet of the medicament (the working principle of ink-jet printers).
- the other microchip which receives and transmits piezoelectric impulses from the first chip to the tablet in the medicine cavity being programmed for recording impacts on the mesh by thrombi and, when triggered externally, sends an impulse to the trigger ⁇ a reader device) regarding the amount of the remaining medicament, so that the medicament could be refilled, or the stent replaced.
- Figure 1 - shows a side view on the stent, in a cross-section, during its insertion into the blood vessel.
- Figure 2 - shows a side view on the stent, in a cross- section, after its insertion into the blood vessel and taking out of the flexible plastic wire.
- Figure 3 - shows a cross-section of the stent A-A, on which a cavity in the stent is visible, along with a crystal or ceramic tablet on its upper part, as well as the first mesh and the flexible plastic wire.
- Figure 4 - shows a cross-section of the stent B-B, on which a mesh built in the base of the stent is shown, as well as its juncture with the crystal or ceramic tablet.
- the invention concerned, stent for catching and breaking up thromboemboli consists of a plastic tube (3), with a medicine cavity (2).
- meshes (7) and (9) made from nitinol, or a material of similar properties and connected to crystal or ceramic tablets (6) and (8), respectively, are transversely inserted.
- Microchip (5) is built in the base of the stent and, via electrically conducting wires, connected to tablets (6) and (8), as well as with microchip (4), which is via electrically conducting wires connected to crystal or ceramic tablet (1), which covers a part of the medicine cavity (2).
- Microchip 5 is programmed in the way that the electrical impulse from the plate 6 is transferred, onto the chip 4 only in case it has detected a micro-deformation of the mesh 7 which is impacted by a thrombus, whereas it is not transferred in case it simultaneously detects a micro-deformation on mesh 9 (e.g. outside bodily impact with a hand in the region of the stent which causes vibration of both meshes).
- Microchip 4 through which the electrical impulse caused by a thrombus is transferred onto the plate 1, is programmed to count the number of thrombus impacts and that, on the basis of outside action sends an impulse to the outside source of action (the reader) about the remaining amount of medicine so that it could be refilled or the stent replaced.
- a flexible plastic wire 10 passes through the mid-part of the meshes 7 and 9 and serves to allow the stent to be inserted into the desired place in the bloodstream and after its positioning there it is extracted.
- each thrombus impact onto the mesh 7 causes its micro-deformation which, as a consequence, has creation of piezoelectricity on the plate 6, whose impulse is transferred through microchips 4 and 5 to the plate 1 and cause it to widen, with which, from the medicine cavity 2, a droplet of medicine is being flowed into bloodstream.
- Plastic tube 6 is made from electrically non-conductive and non toxic plastic granules with the technology of micro-casting, meshes 7 and 9 from nitinol or a material with similar characteristics, while plates 1 ,4 and 5 which cause piezoelectricity i.e. which expand into piezoelectric impulse, from crystal or ceramics. Electricity conducting wires could be of silver or copper.
- the invention stent for catching and breaking up thromboemboli, is inserted and positioned into a blood vessel just like regular stents.
Abstract
The invention concerned, stent for catching and breaking up thromboemboli, consists of a plastic tube (3) into which nitinol meshes are diagonally placed (7) and (9) connected with tablet (6), i.e. (8), made of crystal or ceramics. Two microchips (5) are built into a plastic pipe (5) during the manufacturing process - the one (5) which is connected to the tablets (6) and (8) via current carrying wire and to the other microchip (4) which is, via current carrying wire, connected to the crystal or ceramic tablet (5), which covers a part of space for medication (2). The microchip (5) is programmed in such way that it forwards a micro deformation of the net (7) i.e. electrical impulse from the tablet (6) to the microchip (4) only when it detects the micro deformation of the net (7) hit by a thromboembolus, but does not forward if at the same time a micro deformation is detected on the net (9), while the microchip (4), which forwards an electrical impulse to the plate (1), is programmed for counting the number of thromboemboli hits and, based on an external cause, it sends the impulse to the external source of cause (the reader, which can be placed on a wristband) informing on the amount of medication remaining. The plastic flex (10) is, after inserting and positioning of the stent, extracted from the blood vessel.
Description
STENT FOR CATCHING AND BREAKING UP THROMBOEMBOLI Field of technology to which the invention relates
This invention relates to medical devices, or filters which prevent clogging of blood vessels by thromboemboli.
According to the International Patent Classification, its code is: A61F 2/01, A6 IF 2/86.
Technical problem
The technical problem which is solved with this invention is how to construct a stent which will block the passage and dissolve thrombi on blood vessels which lead to brain, Jungs, heart, while the stent has a transversely positioned mesh which blocks the passage of thrombi, whereby the medicaments for thrombus dissolution is being inserted, which is activated with via piezoelectric impulse caused by the thrombus impacting the mesh.
State of technology
According to the available literature, that is, internet searches of patented (Espacenet) and not patented (Kobson) documents, the currently existing stents are inserted in detected blood vessel constrictions, and do not have a transversely positioned net which would prevent further blood clot motion through the blood vessels, which means that even if the problem of the blood vessel constriction if solved, thrombi can still reach smaller blood vessels in the brain, lungs and the heart.
The thrombi problem is solved differently, that is, via surgical interventions of blood clot removal and use of medicaments for their breakage, which are injected into the blood vessels after their detection or precautionary, and thus diffused throughout the bloodstream, which requires a larger medicament amount compared to if it were injected close to the thrombus. Preventive methods also require constant use of blood dilution medicines.
The essence of the invention
The essence of the invention consists of the following:
- Two transversely positioned nitinol (an alloy of nickel and titanium, which has the property of memorizing its original shape), which are connected to crystal or ceramic tablets, in which piezoelectricity is induced due to micro-deformations on the meshes.
- The base of the stent, made from electrically insulating plastic, with a cavity for the medicament, which is partly covered with a crystal or ceramic tablet, which can stretch via a piezoelectric impulse, created by the impact of the thrombus on the mesh (Lippmann effect), which expels a droplet of the medicament (the working principle of ink-jet printers).
- Microchips built in the stent, one of which is connected to the tablets connected to the meshes and programmed so that the piezoelectric impulse is transmitted to the other chip in the medicament cavity only when it detects a micro-deformation on the first mesh, with which the thrombus collides, and not when it detects two micro-deformations, on both meshes, at the same time (for example, from an external impact, when both meshes vibrate).
- The other microchip, which receives and transmits piezoelectric impulses from the first
chip to the tablet in the medicine cavity being programmed for recording impacts on the mesh by thrombi and, when triggered externally, sends an impulse to the trigger ^a reader device) regarding the amount of the remaining medicament, so that the medicament could be refilled, or the stent replaced.
Short description of the drawings
The invention is shown on the following drawings:
Figure 1 - shows a side view on the stent, in a cross-section, during its insertion into the blood vessel.
Figure 2 - shows a side view on the stent, in a cross- section, after its insertion into the blood vessel and taking out of the flexible plastic wire.
Figure 3 - shows a cross-section of the stent A-A, on which a cavity in the stent is visible, along with a crystal or ceramic tablet on its upper part, as well as the first mesh and the flexible plastic wire.
Figure 4 - shows a cross-section of the stent B-B, on which a mesh built in the base of the stent is shown, as well as its juncture with the crystal or ceramic tablet.
Detailed description of the invention
The invention concerned, stent for catching and breaking up thromboemboli, consists of a plastic tube (3), with a medicine cavity (2). In the tube (3), meshes (7) and (9) made from nitinol, or a material of similar properties and connected to crystal or ceramic tablets (6) and (8), respectively, are transversely inserted. Microchip (5) is built in the base of the stent and, via electrically conducting wires, connected to tablets (6) and (8), as well as with microchip (4), which is via electrically conducting wires connected to crystal or ceramic tablet (1), which covers a part of the medicine cavity (2).
Microchip 5 is programmed in the way that the electrical impulse from the plate 6 is transferred, onto the chip 4 only in case it has detected a micro-deformation of the mesh 7 which is impacted by a thrombus, whereas it is not transferred in case it simultaneously detects a micro-deformation on mesh 9 (e.g. outside bodily impact with a hand in the region of the stent which causes vibration of both meshes). Microchip 4, through which the electrical impulse caused by a thrombus is transferred onto the plate 1, is programmed to count the number of thrombus impacts and that, on the basis of outside action sends an impulse to the outside source of action ( the reader) about the remaining amount of medicine so that it could be refilled or the stent replaced.
A flexible plastic wire 10 passes through the mid-part of the meshes 7 and 9 and serves to allow the stent to be inserted into the desired place in the bloodstream and after its positioning there it is extracted.
In accordance with the idea of the invention, each thrombus impact onto the mesh 7 causes its micro-deformation which, as a consequence, has creation of piezoelectricity on the plate 6, whose impulse is transferred through microchips 4 and 5 to the plate 1 and cause it to widen, with which, from the medicine cavity 2, a droplet of medicine is being flowed into bloodstream.
Ways of industrial and other applications of the invention
The Invention, stent for catching and breaking up thromboemboli, is possible to produce using the current state of technology. Plastic tube 6 is made from electrically non-conductive and non toxic plastic granules with the technology of micro-casting, meshes 7 and 9 from nitinol or a material with similar characteristics, while plates 1 ,4 and 5 which cause piezoelectricity i.e. which expand into piezoelectric impulse, from crystal or ceramics. Electricity conducting wires could be of silver or copper.
The invention, stent for catching and breaking up thromboemboli, is inserted and positioned into a blood vessel just like regular stents.
Claims
Claims
The subjected patent, stent for catching and breaking up of thromboemboli, with a flexible plastic wire (10), characterized in being made up of a plastic wire (3) into which are transversely positioned meshes made of Nitinol (7) and (9), and connected to plates (6) and (8), made of crystal or ceramics, with a built-in microchip into the plastic wire during its casting, connected to the electricity conducting plates (6) and (8) and a microchip (4) which is connected to the plate (1) with an electricity conducting wire made of crystal or ceramics, which covers the area of width of medicinal cavity (2) by which the microchip (5) has been programmed to transfer a micro-deformation of the mesh (7) i.e. electrical impulse from the plate (6) is transferred to microchip (4) only when it has detected micro deformation of meshes (7) which is impacted by a thrombus, while not transferring it in case it simultaneously detects a micro deformation on the mesh (9) while the microchip (4) which transfers the electrical impulse onto the plate (1), is programmed to count the impulse of thrombi hits and based on the outside trigger sends an impulse to the outside source of action (reader) about the remaining amount of medicine.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RS20140090A RS54804B1 (en) | 2014-02-28 | 2014-02-28 | Stent for catching and breaking up thromboemboli |
RSP-2014/0090 | 2014-02-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2015130184A1 true WO2015130184A1 (en) | 2015-09-03 |
Family
ID=51900598
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/RS2015/000006 WO2015130184A1 (en) | 2014-02-28 | 2015-02-24 | Stent for catching and breaking up thromboemboli |
Country Status (2)
Country | Link |
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RS (1) | RS54804B1 (en) |
WO (1) | WO2015130184A1 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017081301A1 (en) * | 2015-11-13 | 2017-05-18 | David Blömer | System for improving blood flow |
WO2021262176A1 (en) * | 2020-06-25 | 2021-12-30 | Bard Peripheral Vascular, Inc. | Lymph conduction system implant |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030032892A1 (en) * | 2001-04-25 | 2003-02-13 | Erlach Julian Van | Nanodevices, microdevices and sensors on in-vivo structures and method for the same |
US20050080481A1 (en) * | 2003-01-27 | 2005-04-14 | Frank Madda | Spiral stent assembly |
WO2006055443A2 (en) * | 2004-11-15 | 2006-05-26 | Izex Technologies, Inc. | Instrumented implantable stents, vascular grafts and other medical devices |
US20070191816A1 (en) * | 2006-02-13 | 2007-08-16 | Boston Scientific Scimed, Inc. | Radio frequency induced drug elution |
-
2014
- 2014-02-28 RS RS20140090A patent/RS54804B1/en unknown
-
2015
- 2015-02-24 WO PCT/RS2015/000006 patent/WO2015130184A1/en active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030032892A1 (en) * | 2001-04-25 | 2003-02-13 | Erlach Julian Van | Nanodevices, microdevices and sensors on in-vivo structures and method for the same |
US20050080481A1 (en) * | 2003-01-27 | 2005-04-14 | Frank Madda | Spiral stent assembly |
WO2006055443A2 (en) * | 2004-11-15 | 2006-05-26 | Izex Technologies, Inc. | Instrumented implantable stents, vascular grafts and other medical devices |
US20070191816A1 (en) * | 2006-02-13 | 2007-08-16 | Boston Scientific Scimed, Inc. | Radio frequency induced drug elution |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017081301A1 (en) * | 2015-11-13 | 2017-05-18 | David Blömer | System for improving blood flow |
WO2021262176A1 (en) * | 2020-06-25 | 2021-12-30 | Bard Peripheral Vascular, Inc. | Lymph conduction system implant |
Also Published As
Publication number | Publication date |
---|---|
RS54804B1 (en) | 2016-10-31 |
RS20140090A1 (en) | 2014-10-31 |
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