WO2015112168A3 - Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier - Google Patents
Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier Download PDFInfo
- Publication number
- WO2015112168A3 WO2015112168A3 PCT/US2014/013063 US2014013063W WO2015112168A3 WO 2015112168 A3 WO2015112168 A3 WO 2015112168A3 US 2014013063 W US2014013063 W US 2014013063W WO 2015112168 A3 WO2015112168 A3 WO 2015112168A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- noribogaine
- excipient
- compositions
- brain barrier
- blood brain
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/549—Sugars, nucleosides, nucleotides or nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
Abstract
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP14880182.2A EP3096794A2 (en) | 2014-01-24 | 2014-01-24 | Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier |
PCT/US2014/013063 WO2015112168A2 (en) | 2014-01-24 | 2014-01-24 | Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier |
AU2014379612A AU2014379612A1 (en) | 2014-01-24 | 2014-01-24 | Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2014/013063 WO2015112168A2 (en) | 2014-01-24 | 2014-01-24 | Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2015112168A2 WO2015112168A2 (en) | 2015-07-30 |
WO2015112168A3 true WO2015112168A3 (en) | 2015-11-26 |
Family
ID=53682084
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2014/013063 WO2015112168A2 (en) | 2014-01-24 | 2014-01-24 | Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP3096794A2 (en) |
AU (1) | AU2014379612A1 (en) |
WO (1) | WO2015112168A2 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2571696B (en) | 2017-10-09 | 2020-05-27 | Compass Pathways Ltd | Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced |
WO2020212948A1 (en) | 2019-04-17 | 2020-10-22 | Compass Pathfinder Limited | Methods of treating neurocognitive disorders, chronic pain and reducing inflammation |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5591738A (en) * | 1994-10-14 | 1997-01-07 | Nda International, Inc. | Method of treating chemical dependency using β-carboline alkaloids, derivatives and salts thereof |
US5925634A (en) * | 1989-10-20 | 1999-07-20 | Washington University | Use of ibogaine for treating neuropathic pain |
US6348456B1 (en) * | 1994-07-25 | 2002-02-19 | Deborah C. Mash | Method of treating chemical dependency in mammals and a composition therefor |
US8637648B1 (en) * | 2010-06-22 | 2014-01-28 | Demerx, Inc. | Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier |
-
2014
- 2014-01-24 WO PCT/US2014/013063 patent/WO2015112168A2/en active Application Filing
- 2014-01-24 EP EP14880182.2A patent/EP3096794A2/en not_active Withdrawn
- 2014-01-24 AU AU2014379612A patent/AU2014379612A1/en not_active Abandoned
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5925634A (en) * | 1989-10-20 | 1999-07-20 | Washington University | Use of ibogaine for treating neuropathic pain |
US6348456B1 (en) * | 1994-07-25 | 2002-02-19 | Deborah C. Mash | Method of treating chemical dependency in mammals and a composition therefor |
US5591738A (en) * | 1994-10-14 | 1997-01-07 | Nda International, Inc. | Method of treating chemical dependency using β-carboline alkaloids, derivatives and salts thereof |
US8637648B1 (en) * | 2010-06-22 | 2014-01-28 | Demerx, Inc. | Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier |
Non-Patent Citations (2)
Title |
---|
PETERSON, A. L. ET AL.: "Treatment of Parkinson's disease with trophic factors.", NEUROTHERAPEUTICS, vol. 5, no. 2, 2008, pages 270 - 280, XP022577726 * |
PLOS ONE, vol. 7, no. Issue 12, 2012 * |
Also Published As
Publication number | Publication date |
---|---|
AU2014379612A1 (en) | 2016-08-11 |
EP3096794A2 (en) | 2016-11-30 |
WO2015112168A2 (en) | 2015-07-30 |
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