WO2015082425A1 - Acquisition de signal physiologique à l'aide d'un dispositif portable - Google Patents

Acquisition de signal physiologique à l'aide d'un dispositif portable Download PDF

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Publication number
WO2015082425A1
WO2015082425A1 PCT/EP2014/076157 EP2014076157W WO2015082425A1 WO 2015082425 A1 WO2015082425 A1 WO 2015082425A1 EP 2014076157 W EP2014076157 W EP 2014076157W WO 2015082425 A1 WO2015082425 A1 WO 2015082425A1
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WIPO (PCT)
Prior art keywords
signal
optical
physiological
optical signal
subject
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PCT/EP2014/076157
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English (en)
Inventor
Weirong MO
Haitao FENG
Georgio Mosis
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Koninklijke Philips N.V.
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Publication of WO2015082425A1 publication Critical patent/WO2015082425A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0015—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by features of the telemetry system
    • A61B5/0017—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by features of the telemetry system transmitting optical signals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/01—Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/024—Detecting, measuring or recording pulse rate or heart rate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
    • A61B5/113—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb occurring during breathing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases

Definitions

  • the present invention relates to physiological signal acquisition, and more particularly, to method, apparatus and system for physiological signal acquisition by utilizing portable device.
  • the invention in particular relates to an apparatus for converting a physiological signal of a subject to an optical signal, a device for converting an optical signal to a physiological signal of a subject, a system for deriving a physiological signal of a subject, a method of converting a physiological signal of a subject to an optical signal and a method of converting an optical signal to a physiological signal of a subject.
  • Physiological signal acquisition is quite important for a subject's health condition or potential risk in terms of particular diseases.
  • the acquisition of the physiological signal involves the professional medical instruments, which makes the cost high and the acquisition procedure not that convenient for the subject.
  • PWV pulse wave velocity
  • ADC analog-digital converter
  • a system for deriving a physiological signal of a subject which comprises an apparatus for emitting an optical signal representing a physiological signal of a subject and a portable device for deriving the physiological signal from the optical signal.
  • the apparatus in the system for converting a physiological signal of a subject to an optical signal comprises a physiological sensor attachable to the subject, for generating an electrical signal in dependence of a measured physiological signal of the subject, an amplitude or a frequency of the electrical signal being indicative of a value of the physiological signal measured by the physiological sensor, a light source for emitting the optical signal having an intensity and one or more wavelength within the visible range and a modulator for modulating the intensity of the optical signal in accordance with the amplitude or frequency of the electrical signal.
  • the intensity of the optical signal corresponds to the luminance (e.g. candela per square metre) of the optical signal emitted, which is controlled by the modulator.
  • a light emitting diode may be used as light source, in which case an LED driver can be used to modulate the intensity of the optical signal.
  • the physiological sensor in the apparatus is one of thermistor for measuring body temperature, an Sp02 sensor for measuring Oxygen saturation (Sp02), a deformation-sensitive sensor for measuring the deformation of the surface and an accelerometer for motion detection.
  • the deformation-sensitive sensor is a sensor having a shape that may be deformed by a force acting on it, wherein the sensor provides an electrical signal in response to a force causing a change of the shape. Examples of a deformation sensitive sensor are strain sensor, piezoelectric sensor or piezoresistive sensor.
  • the output of a physiological sensor is an electrical signal having an amplitude or frequency varying over time, where the amplitude or frequency at a particular time indicates the corresponding value of physiological signal detected by the physiological sensor.
  • the amplitude of the electrical signal provided by the sensor may be indicative of the temperature(C) detected by thermistor, or an oxygen saturation value detected by the Sp02 sensor.
  • the pressure value detected by a piezoelectric sensor, the resistance detected by piezo resistive sensor, the strain value detected by a strain sensor or other values detected may be indicative for respiration by aspirations relevant parameters (e.g. respiration depth) or pulse wave signals.
  • the frequency of the electrical signal obtained from the sensor may be dependent on the recurring or varying pattern in the value of physiological signal, e.g.
  • the intensity of the optical signal varies.
  • the intensity of optical signal is modulated in dependence of the amplitude or frequency of the electrical signal, and in dependence of the type and the parameter of the physiological signal that is being.
  • the respiration rate may be measured, which may be related to the frequency of the electrical signal that is obtained with the sensor, or the respiration depth (e.g. how deep is the individual breathing) which may be related to the amplitude of the electrical signal that is obtained with the sensor.
  • the portable device in the system for converting an optical signal to a physiological signal of a subject comprises an image sensor for acquiring an optical image sequence of the optical signal and a processor for deriving from the optical image sequence of the optical signal the physiological signal, where the value of the physiological signal is dependent on the detected modulation in the intensity of the optical signal in the acquired optical image sequence
  • the portable device 30 may be arranged to receive a predetermined or default type of physiological signal (e.g. heart rate).
  • the portable device may be programmable such that it can interpret a plurality of optical signals and determine for the programmed type of physiological signal the received amplitude or frequency.
  • the intensity of the optical signal in the acquired optical image can be measured by estimating the luminance of the image. For example, it may be implemented by determining the average of the gray scales of all pixels. Other alternatives such as determining the luminance directly from the full color image (RGB color) may also be used.
  • the portable device in the system further comprises a physiological signal identification means configured to enable the device to determine the corresponding physiological signal for the optical signal to be received out of several possible types of physiological signals.
  • the device is able to serve as a universal device to determine a value for a plurality of types of physiological signals instead of being limited to determine a value for only one particular physiological signal by default or predetermination.
  • the present invention proposes a method, apparatus and system for physiological signal acquisition by utilizing portable device, with features of low-cost, ease- of-use and portability. These features increase patients' awareness of their own risks of diseases, such as arteriosclerosis, and help them improve their compliance.
  • the present invention provides desired advantages of instant data assessment functionality, which is of high value for patients caring at home, instant consult service from medical professionals, and convenient data communication and data storing.
  • the portable device based measurement could significantly increase the interactions of working people, who don't have time to do physical exam routinely.
  • the portable device utilized in the system of the present invention may be a conventional cell phone, a tablet computer, or a PDA, etc., as long as it has such an image sensor for acquiring the optical image sequence from the apparatus and a processor for processing the acquired optical image sequence.
  • the portable device may further comprise a memory for storing the derived physiological signal.
  • the portable device may comprise a communication unit for sending the derived physiological signal to a receiving unit or smart phone for review by medical professional.
  • the physiological signal can be acquired equivalently like the professional medical instruments.
  • the calculation of some key parameters of the physiological signal can be computed quickly.
  • the storage capability of portable device the historical data and results can be retrospect anytime anywhere.
  • the built-in communication ability of portable device the acquired signal, computed data, patient's input, and concerns of measurements, can be transmitted to medical professional and obtain the instant feedback service.
  • the apparatus in the system may further comprise an optical fiber for guiding the optical signal.
  • the optical fiber may be a pigtail fiber having an optical connector pre-installed on one end.
  • any other type of optical fiber suitable to guide the optical signal will be in scope of the invention.
  • the portable device may further comprise a camera comprising the image sensor, a camera adaptor mounted on the front of the camera, comprising: an optical band-pass filter for filtering out spray beam in the optical signal; and a collimation lens for coupling the filtered optical signal into the imaging sensor in the camera.
  • the optical signal may be better guided and collimated so that the quality of the optical signal received by the camera may be improved.
  • a system for deriving a physiological signal of a subject comprises a first apparatus attachable to a first artery of the subject and a second apparatus attachable to a second artery of the subject, where the system is arranged to derive a pulse wave velocity, PWV, of the subject, and the device is arranged to receive a first optical signal of the first apparatus and a second optical signal of the second apparatus and derive a PWV in dependence of the received first and second optical signal.
  • PWV pulse wave velocity
  • the device in the system is arranged to acquire a third optical image sequence.
  • Each optical image of the third optical image sequence comprising respective portion of the first optical signal and the second optical signal.
  • the processor is further configured for deriving from the third optical image sequence a first optical image sequence of the first optical signal and a second optical image sequence of the second optical signal, deriving from the first optical image sequence a first arterial pulse wave signal and deriving from the second optical image sequence a second arterial pulse wave signal and deriving a pulse wave velocity PWV of the subject from the first arterial pulse wave signal and the second arterial pulse wave signal.
  • the present invention proposes a PWV measurement method and apparatus, which is based on the optical amplitude modulation technology.
  • the portable device is able to receive two optical signals in one optical image sequence and derive the PWV directly from the received optical image sequence, which results in a high efficiency.
  • the artery pulse signals are picked up by using deformation-sensitive sensors or
  • the implementation proposed in the present invention significantly reduces the system cost and system complexity. If embodied as a gadget affiliated to modern portable device, this system is then featured by low-cost, portability and ease-of-use.
  • a method of generating an electrical signal in dependence of a measured physiological signal of the subject is proposed.
  • the electrical signal has an amplitude or a frequency of the electrical signal being indicative of a value of the physiological signal measured by the physiological sensor
  • a method of acquiring an optical image sequence of an optical signal is proposed. It derives from the optical image sequence of the optical signal the amplitude or a frequency of the physiological signal where the value of the physiological signal is dependent on a modulated intensity of the optical signal in the acquired optical image sequence.
  • a computer program product comprising a set of instructions, which when downloaded into a portable device(e.g. a smart phone) and implemented, are capable of: driving a camera in the portable device to acquire an optical image sequence of the optical signal emitted from the above mentioned apparatus; and driving a processor in the portable device to derive the physiological signal from the optical image sequence of the optical signal.
  • Fig. 1 is a block diagram of an apparatus 10 for emitting an optical signal representing a physiological signal of a subject according to the present invention
  • Fig. 2 is a block diagram of a system 200 for deriving a physiological signal of a subject according to one embodiment of the present invention
  • Fig. 3 is a block diagram of a system 300 for deriving arterial pulse wave signal of a subject according to one embodiment of the present invention
  • Fig. 4 is a block diagram of the system 400 for deriving arterial pulse wave signal of a subject according to another embodiment of the present invention.
  • Fig. 5 schematically shows the internal functional modules of a portable device 30 according to the present invention.
  • Fig. 1 is a block diagram of an apparatus 10 for emitting an optical signal representing a physiological signal of a subject according to the present invention.
  • Fig. 2 is a block diagram of a system 200 for deriving a physiological signal of a subject according to one embodiment of the present invention.
  • the system 200 for deriving a physiological signal of a subject comprises an apparatus 10 for emitting an optical signal representing a
  • physiological signal of a subject and a portable device 30 for receiving the optical signal and deriving a physiological signal of a subject from the optical signal.
  • the apparatus 10 in the system 200 comprises a physiological sensor 11 placed on the subject, for acquiring an electrical signal representing the physiological signal of the subject and a light source 13 for emitting an optical signal.
  • the apparatus 10 further comprises an modulator 12 for modulating the intensity of the optical signal in accordance with the amplitude of the electrical signal.
  • the apparatus 10 further comprises a signal amplifier with reference sign "amp", usually a low-noise instrument amplifier to amplify the electrical signal acquired by the sensor 11. It can be easily understood that the amplifier is optional. In some cases, the electrical signal acquired may be strong enough and the amplifier is not necessary in that case.
  • a signal amplifier with reference sign "amp” usually a low-noise instrument amplifier to amplify the electrical signal acquired by the sensor 11. It can be easily understood that the amplifier is optional. In some cases, the electrical signal acquired may be strong enough and the amplifier is not necessary in that case.
  • the physiological sensor may be various sensors for measuring different physiological parameters of the subject.
  • the physiological sensor 11 in the apparatus 10 may be a thermistor for measuring body temperature.
  • the physiological sensor 11 may be a lighting emitter and sensor for measuring Oxygen saturation (Sp02).
  • the physiological sensor 11 may also be a strain sensor surrounding abdomen of the subject for measuring aspirations relevant parameters.
  • the modulator 12 is powered by a linear DC power supply, and modulates the following light source 13 according to the amplitude of the electrical signal acquired.
  • the modulation may be carried out in various ways, for example optical modulation or electrical modulation, as long as the intensity of LED optical signal can represent the amplitude of the electrical signal.
  • the intensity of the optical signal is of linear relationship to the amplitude of the output electrical signal of the sensor 11.
  • the light source 13 may be a high resolution and sensitivity light source, preferably with the wavelength within visual range of 400-700 nm so that the common camera of the conventional portable device 30 may acquire the optical image sequence of the optical signal emitted from the light source 13.
  • the system 200 for deriving such physiological signal of a subject comprises only one apparatus 10.
  • the system may comprise at least two apparatus.
  • the system 300 for deriving arterial pulse wave signal of a subject comprises two apparatus for emitting an optical signal, which represents the arterial pulse wave signal of a subject.
  • the portable device 30 in the system 200 comprises an image sensor for acquiring an optical image sequence of the optical signal emitted from the apparatus 10 and a processor for deriving the physiological signal from the optical image sequence of the optical signal.
  • the portable device 30 may be arranged to receive a specific type physiological signal, such as temperature, pressure or any other value mentioned above.
  • the portable device 30 utilized in the system 200 of the present invention may be a conventional cell phone, a tablet computer, a laptop, or a PDA, etc., as long as it has a camera for acquiring the optical image sequence from the apparatus 10 and a processor for signal processing but being further adapted for deriving the physiological signal from the optical image sequence.
  • the portable device 30 may further comprise a memory for storing the derived physiological signal.
  • the portable device in the system further comprises a physiological signal identification means configured to enable the device to determine the corresponding physiological signal for the optical signal to be received out of several possible types of physiological signals.
  • the device is able to serve as a universal device to determine a value for a plurality of types of physiological signals instead of being limited to determine from a received optical value a value for a single predetermined physiological signal.
  • the portable device may comprise a user interface for allowing the user to change the setting of the portable device and select a type from a predetermined set of physiological signals. This set may for example comprise heart rate, respiration rate, respiration depth, oxygen saturation (Sp02), body temperature).
  • the portable device comprises a read out unit and the apparatus comprises an RFID storing data that identifies the sensor and the type of physiological that may be measured with said sensor.
  • the readout unit may obtain the data from the RFID.
  • the device may change its settings in correspondence with the identified the sensor and the type of physiological.
  • the portable device 30 may further comprise a communication unit for sending the derived physiological signal to a medical professional.
  • the physiological signal can be acquired equivalently like the professional medical instruments.
  • the calculation of some key parameters of the physiological signal can be computed quickly.
  • the historical data and results can be retrospect anytime anywhere.
  • the built-in communication ability of portable device the acquired signal, computed data, patient's input, and concerns of measurements, can be transmitted to medical professional and obtain the instant feedback service.
  • Fig. 3 is a block diagram of a system 300 for deriving arterial pulse wave signal of a subject according to one embodiment of the present invention.
  • the system 300 needs two apparatus 10 and 20 for emitting optical signals representing the arterial pulse wave signal of a subject and one portable device 30 for receiving the optical signals and deriving the arterial pulse wave signal from the optical signals.
  • the physiological sensor 11 in the first apparatus 10 is placed above a first artery of the subject, for outputting a first electrical signal representing the arterial pulse wave signal of the subject
  • the physiological sensor 21 in the second apparatus 20 is placed above a second artery of the subject different from the first artery, for outputting a second electrical signal representing the arterial pulse wave signal of the subject.
  • carotid artery is selected as the first artery and femoral artery is selected as the second artery.
  • femoral artery is selected as the second artery.
  • other arteries may be also possible according to different requirements.
  • the light source 13 in the first apparatus 10 emits a first optical signal and the light source 23 in the second apparatus 20 emits a second optical signal.
  • the camera of the portable device 30 acquires an optical image sequence of the first optical signal and an optical image sequence of the second optical signal, and the processor of the portable device 30 derives a first arterial pulse wave signal from the optical image sequence of the first optical signal and derives a second arterial pulse wave signal from the optical image sequence of the second optical signal.
  • the physiological sensors 11 and 21 in the system 300 for deriving arterial pulse wave signal of a subject are deformation-sensitive sensors for outputting electrical signals representing the arterial pulse wave signal of the subject.
  • the physiological sensors 11 and 21 in the system 300 may be accelerometers as well, as long as they can output electrical signals representing the arterial pulse wave signal of the subject.
  • the minimal image acquisition speed can reach 25-30 frames per second (fps) for an image resolution at least 800 by 480 pixels.
  • This image resolution and image acquisition speed allow the signal integrity for most pulse wave signals, whose signal spectra normally range within 0.35Hz-5 Hz. Therefore the time-resolved image contains full information of pulse wave signal and the pulse wave signal can be completely restored without losing any featured information.
  • Fig. 4 is a block diagram of the system 400 for deriving arterial pulse wave signal of a subject according to another embodiment of the present invention.
  • each of the apparatus 10 and 20 in the system 400 further comprises an optical fiber 14 and 24 for guiding the respective optical signal.
  • the portable device 30 may further comprise a camera adaptor 31 mounted on the front of the camera.
  • the camera adaptor 31 comprises a front lens 310, which is divided into two parts by an opaque blocker 310a, for splitting the received optical input from two fibers.
  • the adaptor 31 comprises an optical band-pass filter 311 to filter out the spray beam and make the beam nearly monochromatic, and a collimation lens 312 to couple the optical images into the imaging sensor, for example CCD or CMOS sensors, of the camera properly.
  • the camera adaptor 31 shown in Fig. 4 comprises a front lens 310 for splitting the receiving optical input from two fibers, it can be easily understood that it is an optional component.
  • the camera adaptor may also be utilized and in that case, the front lens with opaque blocker is not necessary.
  • the optical signal may be better guided and collimated so that the quality of the optical signal received by the camera may be improved.
  • the processor of the portable device 30 is further configured for deriving a pulse wave velocity PWV of the subject from the first arterial pulse wave signal and the second arterial pulse wave signal.
  • FIG. 5 schematically shows the internal functional modules of the portable device 30 according to the present invention.
  • the portable device for example a cell phone, firstly records a sequence of time-resolved optical intensity images. See 301, each image is then split into two parts for acquiring two channels of signals. For each channel, the integral of image intensity within the region of interest (ROI) is summed and regarded as a single temporal point of the whole pulse wave (302). Once the entire image sequences of two channels are recorded, two completed pulse waveforms of two channels are then reconstructed (303). Then the periodic cycle detection algorithm detects the period of the pulse cycle, by utilizing well established algorithm of foot-detection or maximal slope point detection.
  • ROI region of interest
  • Dist/PTT (305), where Dist is the surface distance between two measurement sites, and PTT is the pulse transmission time.
  • the PWV results and the risk categorization can be done by built-in clinical support functions.
  • the results can be displayed on the phone (306), stored in the local database or remote database (307), or directly sent to associate medical professional via wireless
  • ECG electrocardiograph
  • the ECG signal which is commonly used as time-reference signal in most conventional PWV assessment modalities, is not used in this invention. This is because the ECG signal encloses frequency of 40 Hz and above, especially for the upstroke of the R-wave. For most cell phone camera, the image acquisition cannot respond as quickly as this change of ECG signal. If using this incomplete ECG signal as the time reference, in particularly using the method of maximal-slope middle point method for determining consecutive PTTs between periodic pulse signals, phase error will occur and resultantly reduce the PWV accuracy.
  • the present invention also proposes an innovative PWV measurement method and system, which is based on the optical amplitude modulation technology.
  • the artery pulse signals are picked up by using deformation-sensitive sensors or accelerometers, but the transmission and conversion functions are replaced by optical solution, in order to utilize the advantages of portable device.
  • the implementation proposed in the present invention significantly reduces the system cost and system complexity. If embodied as a gadget affiliated to modern portable device, this system is then featured by low-cost, portability and ease-of-use.
  • the portable device based platform and the multi-thread computation ability can empower the handy convenience for any signals process, which dynamically varies in amplitude and in a 'slow' frequency, for example, the body temperature, Sp02, aspirations relevant parameters obtained by strain sensor surrounding abdomen, and artery pulse wave signal, etc., as long as the signal frequency is within the Nyquist sampling frequency range.
  • the method for modulating an optical signal emitted from a light source is about the operation of the apparatus 10 side and comprises the step of acquiring an electrical signal representing a physiological signal of a subject with a physiological sensor placed on the subject; and the step of modulating the intensity of the optical signal in accordance with the amplitude of the electrical signal.
  • the present invention has also disclosed a method for deriving a physiological signal of a subject, which is about the operation of the whole system 200 and comprises the steps of acquiring an electrical signal representing the physiological signal of the subject with a physiological sensor placed on the subject; modulating intensity of an optical signal emitted from a light source in accordance with the amplitude of the electrical signal; acquiring an optical image sequence of the optical signal; and deriving the physiological signal from the optical image sequence of the optical signal.
  • the method performed in the portable device may be carried out by a computer program, i.e., gadget, which when downloaded into the portable device 30 and implemented, are capable of driving the camera in the portable device 30 to acquire an optical image sequence of the optical signal emitted from the apparatus 10, and driving a processor in the portable device 30 to derive the physiological signal from the optical image sequence of the optical signal.
  • a computer program i.e., gadget, which when downloaded into the portable device 30 and implemented, are capable of driving the camera in the portable device 30 to acquire an optical image sequence of the optical signal emitted from the apparatus 10, and driving a processor in the portable device 30 to derive the physiological signal from the optical image sequence of the optical signal.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
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  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

La présente invention concerne un procédé, un appareil et un système pour une acquisition de signal physiologique à l'aide d'un dispositif portable. Selon un aspect de la présente invention, un système pour obtenir un signal physiologique d'un sujet comprend : un appareil pour émettre un signal optique représentant un signal physiologique d'un sujet, comprenant : un capteur physiologique placé sur le sujet pour acquérir un signal électrique représentant le signal physiologique du sujet ; une source de lumière pour émettre le signal optique ; et un modulateur pour moduler l'intensité du signal optique en fonction de l'amplitude du signal électrique. Le système comprend en outre un dispositif portable, comprenant : une caméra pour acquérir une séquence d'image optique du signal optique émis par l'appareil ; et un processeur pour obtenir le signal physiologique à partir de la séquence d'image optique du signal optique. Le nouveau procédé a un faible coût, et est facile à utiliser et à transporter. Ces caractéristiques visent à accroître la sensibilisation de patients de leurs propres risques de maladies, telles que l'artériosclérose, et les aider à améliorer leur conformité. De plus, le dispositif a les avantages souhaités suivants : une fonctionnalité d'évaluation de données instantanées, qui a une grande valeur pour des patients soignés à domicile, un service de consultation instantanée de professionnels médicaux, une communication de données pratique et un stockage de données pratique.
PCT/EP2014/076157 2013-12-05 2014-12-02 Acquisition de signal physiologique à l'aide d'un dispositif portable WO2015082425A1 (fr)

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CNPCT/CN2013/088638 2013-12-05
CN2013088638 2013-12-05
EP14156898.0 2014-02-27
EP14156898 2014-02-27

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