WO2015066439A8 - Methods of treating hematological malignancies - Google Patents

Methods of treating hematological malignancies Download PDF

Info

Publication number
WO2015066439A8
WO2015066439A8 PCT/US2014/063367 US2014063367W WO2015066439A8 WO 2015066439 A8 WO2015066439 A8 WO 2015066439A8 US 2014063367 W US2014063367 W US 2014063367W WO 2015066439 A8 WO2015066439 A8 WO 2015066439A8
Authority
WO
WIPO (PCT)
Prior art keywords
methods
hematological malignancies
treating hematological
treating
malignancies
Prior art date
Application number
PCT/US2014/063367
Other languages
French (fr)
Other versions
WO2015066439A3 (en
WO2015066439A2 (en
Inventor
Matthew J. HAWRYLUK
Jie He
Vincent A. MILLER
Philip James STEPHENS
Omar Abdel-Wahab
Jeffrey R. GARDNER
Ross LEVINE
Marcel Van Den Brink
Andrew ZELENETZ
Original Assignee
Foundation Medicine, Inc.
Memorial Sloan-Kettering Cancer Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Foundation Medicine, Inc., Memorial Sloan-Kettering Cancer Center filed Critical Foundation Medicine, Inc.
Publication of WO2015066439A2 publication Critical patent/WO2015066439A2/en
Publication of WO2015066439A8 publication Critical patent/WO2015066439A8/en
Publication of WO2015066439A3 publication Critical patent/WO2015066439A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Abstract

Methods and compositions for treating and detecting hematological malignancies are disclosed.
PCT/US2014/063367 2013-11-01 2014-10-31 Methods of treating hematological malignancies WO2015066439A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361898818P 2013-11-01 2013-11-01
US61/898,818 2013-11-01

Publications (3)

Publication Number Publication Date
WO2015066439A2 WO2015066439A2 (en) 2015-05-07
WO2015066439A8 true WO2015066439A8 (en) 2015-06-25
WO2015066439A3 WO2015066439A3 (en) 2015-11-05

Family

ID=53005385

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2014/063367 WO2015066439A2 (en) 2013-11-01 2014-10-31 Methods of treating hematological malignancies

Country Status (1)

Country Link
WO (1) WO2015066439A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105560217B (en) * 2016-03-01 2019-03-01 周斌 Application of the honokiol in acute myelocytic leukemia
NZ755835A (en) 2017-01-17 2023-12-22 Heparegenix Gmbh Protein kinase inhibitors for promoting liver regeneration or reducing or preventing hepatocyte death

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060134068A1 (en) * 2004-11-09 2006-06-22 Mount Sinai School Of Medicine Of New York University Treatment of cancer by simultaneous inhibiton of BRAF and restoration or mimicry of p16INK4A activity
EP1968607B1 (en) * 2005-12-02 2014-01-15 Nabil Habib Lab Treatment of cancer and other diseases
US20100120080A1 (en) * 2008-11-03 2010-05-13 Quest Diagnostics Investments Incorporated Cancer diagnosis using ki-67
EP2635286A4 (en) * 2010-11-05 2014-11-12 Glaxosmithkline Ip No 2 Ltd Methods for treating cancer
WO2013001372A2 (en) * 2011-06-30 2013-01-03 University Of Oslo Methods and compositions for inhibition of activation of regulatory t cells
WO2014071419A2 (en) * 2012-11-05 2014-05-08 Foundation Medicine, Inc. Novel fusion molecules and uses thereof

Also Published As

Publication number Publication date
WO2015066439A3 (en) 2015-11-05
WO2015066439A2 (en) 2015-05-07

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