WO2015038092A3 - Carbon dioxide and saline nasal delivery methods and delivery devices - Google Patents

Carbon dioxide and saline nasal delivery methods and delivery devices Download PDF

Info

Publication number
WO2015038092A3
WO2015038092A3 PCT/US2013/000207 US2013000207W WO2015038092A3 WO 2015038092 A3 WO2015038092 A3 WO 2015038092A3 US 2013000207 W US2013000207 W US 2013000207W WO 2015038092 A3 WO2015038092 A3 WO 2015038092A3
Authority
WO
WIPO (PCT)
Prior art keywords
carbon dioxide
patient
methods
delivery
delivery devices
Prior art date
Application number
PCT/US2013/000207
Other languages
French (fr)
Other versions
WO2015038092A2 (en
Inventor
Kenneth P. Glynn
Original Assignee
Glynn Kenneth P
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glynn Kenneth P filed Critical Glynn Kenneth P
Priority to MX2016002968A priority Critical patent/MX2016002968A/en
Priority to CA2923793A priority patent/CA2923793C/en
Priority to AU2013400183A priority patent/AU2013400183B2/en
Priority to PCT/US2013/000207 priority patent/WO2015038092A2/en
Priority to EP13893220.7A priority patent/EP3043650A4/en
Priority to JP2016541940A priority patent/JP2016529082A/en
Publication of WO2015038092A2 publication Critical patent/WO2015038092A2/en
Publication of WO2015038092A3 publication Critical patent/WO2015038092A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/006—Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
    • A61M11/007—Syringe-type or piston-type sprayers or atomisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/02—Sprayers or atomisers specially adapted for therapeutic purposes operated by air or other gas pressure applied to the liquid or other product to be sprayed or atomised
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0031—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up by bursting or breaking the package, i.e. without cutting or piercing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/14—Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/02—Gases
    • A61M2202/0225—Carbon oxides, e.g. Carbon dioxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0618—Nose

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Otolaryngology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mechanical Engineering (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Methods for treating ailments in a patient in need thereof includes the step of directing a therapeutic, non-inhaled dosage to at least one nasal cavity of the patient through a flow regulating device while the patient refrains from inhaling. The dosage includes a saline fluid and a gas containing carbon dioxide, and, in some dosages, additional active component(s) wherein the therapeutic, non-inhaled dosage is delivered at a specified flow rate; the delivery devices are also included.
PCT/US2013/000207 2013-09-10 2013-09-10 Carbon dioxide and saline nasal delivery methods and delivery devices WO2015038092A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
MX2016002968A MX2016002968A (en) 2013-09-10 2013-09-10 Carbon dioxide and saline nasal delivery methods and delivery devices.
CA2923793A CA2923793C (en) 2013-09-10 2013-09-10 Carbon dioxide and saline nasal delivery methods and delivery devices
AU2013400183A AU2013400183B2 (en) 2013-09-10 2013-09-10 Carbon dioxide and saline nasal delivery methods and delivery devices
PCT/US2013/000207 WO2015038092A2 (en) 2013-09-10 2013-09-10 Carbon dioxide and saline nasal delivery methods and delivery devices
EP13893220.7A EP3043650A4 (en) 2013-09-10 2013-09-10 Carbon dioxide and saline nasal delivery methods and delivery devices
JP2016541940A JP2016529082A (en) 2013-09-10 2013-09-10 Nasal delivery method and delivery device for carbon dioxide and saline

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2013/000207 WO2015038092A2 (en) 2013-09-10 2013-09-10 Carbon dioxide and saline nasal delivery methods and delivery devices

Publications (2)

Publication Number Publication Date
WO2015038092A2 WO2015038092A2 (en) 2015-03-19
WO2015038092A3 true WO2015038092A3 (en) 2015-07-16

Family

ID=52666483

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2013/000207 WO2015038092A2 (en) 2013-09-10 2013-09-10 Carbon dioxide and saline nasal delivery methods and delivery devices

Country Status (6)

Country Link
EP (1) EP3043650A4 (en)
JP (1) JP2016529082A (en)
AU (1) AU2013400183B2 (en)
CA (1) CA2923793C (en)
MX (1) MX2016002968A (en)
WO (1) WO2015038092A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3013821C (en) * 2016-02-05 2022-05-10 Clover Hill Healthcare, Inc. Nasal treatment delivery device with carbon dioxide and saline, and methods, including low flow rates
US11712523B2 (en) 2018-09-28 2023-08-01 Achilleus LLC Secure device for delivering medications
GB2586301B (en) * 2020-04-07 2021-08-25 Splash Tm Gmbh Stable-Foam inhalation Device and Cartridge

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090236374A1 (en) * 2005-11-03 2009-09-24 Reseal International Limited Partnership Metered Drop Push Button Dispenser System
US20110046546A1 (en) * 1999-07-12 2011-02-24 Capnia, Inc. Methods for treating headaches
WO2013063413A1 (en) * 2011-10-28 2013-05-02 Ampio Pharmaceuticals, Inc. Treatment of rhinitis

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06312019A (en) * 1993-04-30 1994-11-08 Shinko Kagaku Kk Liquid medicine spray receptacle
JP2003040766A (en) * 2001-07-26 2003-02-13 Kao Corp Tool for cleaning nasal cavity
DE20121474U1 (en) * 2001-09-26 2003-01-16 Zellner Gerhard Composition for preventing and treating respiratory tract disorders, e.g. bronchitis or colds, comprising aqueous liquid containing dissolved carbon dioxide
IL160936A0 (en) * 2004-02-05 2004-08-31 Scott A Cordray Nasal spray and wash
CN1669559A (en) * 2004-03-15 2005-09-21 刘展欣 Medicine for treating rhinitis
US7875001B2 (en) * 2008-02-25 2011-01-25 Americo Michael Minotti Multi medication nasal spray device and method
JP5959269B2 (en) * 2011-05-10 2016-08-02 伸晃化学株式会社 Spray container
AU2012267938B2 (en) * 2011-06-07 2017-05-04 Parion Sciences, Inc. Methods of treatment
JP6258230B2 (en) * 2012-02-16 2018-01-10 キャップニア， インコーポレイテッド Gas dispenser with diffusion nosepiece

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110046546A1 (en) * 1999-07-12 2011-02-24 Capnia, Inc. Methods for treating headaches
US20090236374A1 (en) * 2005-11-03 2009-09-24 Reseal International Limited Partnership Metered Drop Push Button Dispenser System
WO2013063413A1 (en) * 2011-10-28 2013-05-02 Ampio Pharmaceuticals, Inc. Treatment of rhinitis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP3043650A4 *

Also Published As

Publication number Publication date
AU2013400183B2 (en) 2017-04-27
EP3043650A4 (en) 2017-11-08
CA2923793A1 (en) 2015-03-19
CA2923793C (en) 2018-02-27
EP3043650A2 (en) 2016-07-20
MX2016002968A (en) 2016-12-02
WO2015038092A2 (en) 2015-03-19
AU2013400183A1 (en) 2016-03-17
JP2016529082A (en) 2016-09-23

Similar Documents

Publication Publication Date Title
JP2015042287A5 (en)
BR112015024869A8 (en) use of a therapeutic agent and / or carbon dioxide to treat a patient and apparatus and methods for therapeutically treating a patient
MX2018001321A (en) Combined respiratory muscle training and oscillating positive expiratory pressure device.
MX2022008236A (en) Methods of administering high concentrations of nitric oxide.
TR201909589T4 (en) Inhalation device for use in aerosol therapy of respiratory diseases.
WO2014204511A3 (en) Compliance monitoring for asthma inhalers
SG10201807070YA (en) Respiratory mask with nasogastric tube path
JP2014138843A5 (en)
NZ630609A (en) Discreet respiratory therapy system
IN2014DN07474A (en)
WO2014153473A3 (en) Methods and apparatus for reducing the risk of surgical site infections
NZ701073A (en) Method and system for the administration of a pulmonary surfactant by atomization
SG10201808472UA (en) Pressurizing masks, systems and methods
CY1124713T1 (en) METHODS OF ADMINISTERING HIGH CONCENTRATIONS OF NITRIC OXIDE
AR095547A1 (en) NEBULIZER FOR BABIES AND PATIENTS WITH RESPIRATORY COMMITMENT
WO2015035315A3 (en) Temperature measurment and feedback for therapeutic hypothermia
TR201109804A2 (en) Single dose inhalation device.
EP3300734A3 (en) Use of levocetirizine and montelukast in the treatment of autoimmune disorders
CR20190300A (en) Pharmaceutical dosage forms containing task-1 and task-3 channel inhibitors, and the use of same in breathing disorder therapy
NZ769954A (en) Syringe devices for use in an emergency
MX2015012315A (en) Use of levocetirizine and montelukast in the treatment of traumatic injury.
EP4309718A3 (en) Gas therapy system for delivery of medicament
WO2015038092A3 (en) Carbon dioxide and saline nasal delivery methods and delivery devices
WO2015174864A8 (en) Methods and apparatus for flow therapy
EA201591415A1 (en) PHARMACEUTICAL COMPOSITIONS, INCLUDING MULTICOMPONENT CRYSTALLINE PARTICLES, SUITABLE FOR USE IN INHALATION THERAPY

Legal Events

Date Code Title Description
DPE1 Request for preliminary examination filed after expiration of 19th month from priority date (pct application filed from 20040101)
WWE Wipo information: entry into national phase

Ref document number: MX/A/2016/002968

Country of ref document: MX

ENP Entry into the national phase

Ref document number: 2923793

Country of ref document: CA

Ref document number: 2016541940

Country of ref document: JP

Kind code of ref document: A

NENP Non-entry into the national phase

Ref country code: DE

ENP Entry into the national phase

Ref document number: 2013400183

Country of ref document: AU

Date of ref document: 20130910

Kind code of ref document: A

REG Reference to national code

Ref country code: BR

Ref legal event code: B01A

Ref document number: 112016005235

Country of ref document: BR

REEP Request for entry into the european phase

Ref document number: 2013893220

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2013893220

Country of ref document: EP

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 13893220

Country of ref document: EP

Kind code of ref document: A2

ENP Entry into the national phase

Ref document number: 112016005235

Country of ref document: BR

Kind code of ref document: A2

Effective date: 20160309