WO2015015226A1 - Dispositif faiblement invasif et méthode pour traiter des troubles vasculaires - Google Patents

Dispositif faiblement invasif et méthode pour traiter des troubles vasculaires Download PDF

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Publication number
WO2015015226A1
WO2015015226A1 PCT/GB2014/052378 GB2014052378W WO2015015226A1 WO 2015015226 A1 WO2015015226 A1 WO 2015015226A1 GB 2014052378 W GB2014052378 W GB 2014052378W WO 2015015226 A1 WO2015015226 A1 WO 2015015226A1
Authority
WO
WIPO (PCT)
Prior art keywords
vein
sheath
guide wire
medical device
expansible member
Prior art date
Application number
PCT/GB2014/052378
Other languages
English (en)
Inventor
Martin SABADO
David Greenstein
Original Assignee
Sabado Martin
David Greenstein
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sabado Martin, David Greenstein filed Critical Sabado Martin
Publication of WO2015015226A1 publication Critical patent/WO2015015226A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32—Surgical cutting instruments
    • A61B17/3205—Excision instruments
    • A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32—Surgical cutting instruments
    • A61B17/3205—Excision instruments
    • A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
    • A61B17/320725—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions with radially expandable cutting or abrading elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32—Surgical cutting instruments
    • A61B17/3205—Excision instruments
    • A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
    • A61B17/32075—Pullback cutting; combined forward and pullback cutting, e.g. with cutters at both sides of the plaque
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09—Guide wires
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00008—Vein tendon strippers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/12181—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices
    • A61B17/12186—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices liquid materials adapted to be injected
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00743—Type of operation; Specification of treatment sites
    • A61B2017/00778—Operations on blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22051—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with an inflatable part, e.g. balloon, for positioning, blocking, or immobilisation
    • A61B2017/22061—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with an inflatable part, e.g. balloon, for positioning, blocking, or immobilisation for spreading elements apart
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32—Surgical cutting instruments
    • A61B2017/320004—Surgical cutting instruments abrasive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A61M2025/0024—Expandable catheters or sheaths
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09—Guide wires
    • A61M2025/09008—Guide wires having a balloon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M2025/1043—Balloon catheters with special features or adapted for special applications
    • A61M2025/1063—Balloon catheters with special features or adapted for special applications having only one lumen used for guide wire and inflation, e.g. to minimise the diameter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M2025/1043—Balloon catheters with special features or adapted for special applications
    • A61M2025/1086—Balloon catheters with special features or adapted for special applications having a special balloon surface topography, e.g. pores, protuberances, spikes or grooves

Definitions

  • the present invention relates to devices and methods for treating vascular disorders. More particularly, present invention provides minimally invasive methods and medical devices for endolumina!ly treating blood vessels of a mammal.
  • Varicose veins are blood vessels with deficient valves, which cause retrograde blood flow and enlarge the vessel walls, affecting both women and men. This vein disorder is most common in the superficial veins of the legs, which are subject to high pressure when standing. Varicose veins are not only a cosmetic problem, but also a medical condition. They are often painful, especially when standing or walking, which can lead to ulcers.
  • vascular disorders such as varicose veins
  • surgical and non-surgical methods such as vein stripping, phlebectomy, endovenous laser treatments, radiofrequency ablation and foam sclerotherapy.
  • problems including the requirement for costly equipment, drug side-effects, long recovery periods, and high recurrence rates.
  • general anesthesia is required for some of these treatments, particularly for larger veins, and with it board-certified medical professionals and precautionary measures need to be taken in case serious complications arise, such as heart attacks, strokes, brain damage or even death. Other complications such as deep vein thrombosis, pulmonary embolism and infections due to the wounds generated are also possible.
  • risks connected with sclerotherapy procedures including allergic reaction to the injected fluid or its side-effects.
  • U.S. Patent No. 5,047,013 discloses a probe comprising a flexible plastic tube with a tip portion, and at least one opening in the region of the tip portion for injecting a sclerosing agent. Risks associated with injecting a sclerosing agent include allergic reaction to the injected fluid and its potential drug side-effects. If the use of sclerosing agent can be reduced or avoided altogether it would also reduce costs associated with the treatment and recovery from the treatment. Summary of the Invention
  • the invention provides a medical device for treating vascular disorders comprising:
  • a flexible sheath suitable for insertion into a vein, the flexible sheath having an open ended central bore through which a guide wire may pass;
  • an expansible member coupled to, or forming part of, the sheath, the expansible member having a roughened outer surface and configured to expand from a first configuration to a second configuration when the sheath is inserted in a vein.
  • a device in accordance with the invention has the advantage of being simple and inexpensive to manufacture and simple to use. It does not require a catheter for placement within a vessel to be treated and has few components. In general, the fewer component parts to a device the less susceptible to defects and failure it is. Due to the roughened surface of the expansible member, a preselected section of the vessel wall can be damaged by moving the roughened surface across that section of the vessel. As a result of the damage, the vessel collapses.
  • the expansible member advantageously comprises one or more inflatable members.
  • the inflatable member or members may be a polymeric balloon.
  • the roughened outer surface maybe formed using a number of different materials. For example, diamond chips may be fixed to an outer surface of the expansible member. The diamond chips may of the order of 1- 30 microns in diameter.
  • the diamond chips may be applied to the expansible member in a slurry using a electroplating or electroless plating. Alternatively, the diamond chips may be fixed to the expansible member using an adhesive. As an alternative metal wire or metal filings may be fixed to an outer surface of the expansible member to form the roughened surface.
  • the sheath may include one or more inflation lumens through which inflation fluid may pass to inflate the one or more inflatable members.
  • the inflation fluid may be saline or may be air, for example. If a plurality of inflation lumens are provided, each inflation lumen may supply a different inflatable member so that the length of the roughened surface in contact with a vessel wall can be selected by selecting which inflatable members to inflate.
  • the expansible member may form a part of an exterior surface of the sheath.
  • the roughened surface preferably does not extend proud of the surrounding exterior surface of the sheath.
  • the roughened surface in an uninflated state, may be positioned below the level of the exterior surface of the adjacent portions of the sheath. This reduces the possibility of damage to the areas of the vessel that are not to be treated, as the device is inserted or withdrawn from the vessel.
  • the sheath has a rounded end to reduce the possibility of damage to vessels as the device is inserted and positioned within the vessel.
  • the central bore may be dimensioned such that a thermal treatment device may be inserted through it and positioned within the vessel.
  • a thermal treatment device may be inserted through it and positioned within the vessel.
  • a fibre optic cable may be passed through the central bore to the treatment site so that laser treatment can be applied to the vessel. This may complement the mechanical treatment provided by the roughened surface and may be useful for larger vessels in particular.
  • the additional mechanical treatment may allow thermal treatment to be effective at lower power, meaning less pain for the patient and avoiding the need for general anesthesia.
  • a radio frequency treatment device may be passed through the central bore to allow radio frequency treatment to be carried out together with the mechanical treatment.
  • a sclerosing agent may be delivered to the treatment site through the central bore.
  • a method for treating vascular disorders comprising the steps of: introducing a guide wire inside a vein to be treated; introducing a device in accordance with any one of claims 1 to 6 into the vein, wherein the flexible sheath is positioned around the guide wire so that the guide wire extends through the central bore; positioning a distal end of the device at a preselected treatment site inside the vein; expanding the expansible member to the second configuration so that the roughened surface contacts a wall of the vein; and moving the device and the guide wire through the vein with the expansible member in contact with the wall.
  • the method does not require the use of catheter.
  • the device simply fits around the guide wire. This simplifies the procedure when compared to prior treatment methods.
  • a section of the vessel wall is damaged by moving the roughened surface across that section of the vessel.
  • the vessel collapses.
  • the medical practitioner performing the procedure may simply withdraw the device through the vein with the expansible member in contact with the wall. However, the practitioner may use other movements, such as rotation and movement back and forth.
  • the medical practitioner is given direct tactile feedback as the method is performed, providing an indication of the abrasive force being applied to the vein wall.
  • the practitioner may alter the degree of expansion of the expansible member to increase or reduce the abrasive force and so suit different vessels and different sections of a single vessel.
  • the pressure of the inflation fluid may be altered to adjust the diameter of the inflatable member.
  • the ability to adjust the diameter means that only a single device need be manufactured and supplied to treat different sized vessels. This in turn allows production costs to be reduced.
  • the method may further comprise a complementary vessel treatment, such as thermal treatment.
  • the method may further comprise passing a fibre optic cable through the central bore to the treatment site and apply laser light through the fibre optic cable to the treatment site.
  • a radio frequency treatment device may be passed through the central bore and radio frequency radiation applied to the treatment site.
  • a sclerosing agent may be passed through the central bore and applied to the treatment site.
  • the expansible member may be moved back and forth across the treatment site to massage the sclerosing agent into the vessel wall.
  • the guide wire and device may be introduced into the vein under ultrasound guidance.
  • Fig. 1 shows an embodiment of present invention, comprising a medical device for minimally invasive treatments of varicose veins
  • Fig. 2 shows the device of Figure 1 , with the inflatable member in an uninflated condition
  • Figure 3 is a cross-section through the device of Figure 1 in the region of the inflatable member; and Figure 4 is a cross-section through the device of Figure 1 remote from the inflatable member, Detailed Description
  • FIG. 1 illustrates a medical device 100 for treating vascular disorders.
  • the device 100 comprises a hollow sheath 102 and an inflatable member 104 close to its proximal tip.
  • the sheath is at least as long as the length of a vessel to be treated and typically is longer, allowing insertion into the vascular system remote from the section of a vessel to be treated. In this example, the sheath is approximately 50 centimetres long.
  • the sheath defines a central bore 103, running along its length. In this example, the diameter of the sheath is 3mm, with the central bore having a diameter of 1.5 mm. However, it should be clear that the sheath may be made with larger or smaller diameter to suit a particular application.
  • the sheath is formed from a flexible material, such as silicone elastomer.
  • the inflatable member 104 in this embodiment is a balloon formed from an elastic materia! such as latex, polyurethane, nylon elastomer, or other thermoplastic elastomer.
  • an elastic materia! such as latex, polyurethane, nylon elastomer, or other thermoplastic elastomer.
  • non-elestomeric materials may be used, such as polyethylene terephthalate (PET).
  • PET polyethylene terephthalate
  • the inflatable member has a roughened surface formed from diamond chips, which have been electroplated to the inflatable member 104 in a nickel slurry. Other abrasive materials may be used such as steel wire or filings, Alternatively hooks or bristles may be adhered to the inflatable member.
  • the inflatable member may be of variable length, but in this embodiment is 2cm long.
  • the inflatable member extends around the circumference of a reduced diameter portion of the sheath 102, as shown in Figures 2 and 3 and described below.
  • the inflatable member may be fixed to the
  • the inflatable member 104 is shown in an inflated condition, within a vessel 106 that is being treated.
  • the roughened surface is in contact with a wall of the vessel.
  • the device is shown with the inflatable member in an uninflated condition.
  • Figure 3 is a cross-section through the device shown in Figures 1 and 2, in the region of the inflatable member, with the inflatable member in an uninflated condition.
  • the sheath has a reduced diameter in the region covered by the inflatable member. This allows the roughened surface of the inflatable member to have a diameter smaller than the diameter of the surrounding portions of the sheath, as shown in Figure 2. This reduces the likelihood of the roughened surface contacting and damaging the vessel walls when in an uninflated condition.
  • the inflatable member can be inflated with a fluid such as air or saline water, that is supplied through an inflation lumen 108, shown in Figure 3.
  • the inflation lumen 108 extends from a distal end of the sheath 102 to the inflatable member 104.
  • Figure 4 is a cross section through the sheath at a position distal of the inflatable member.
  • the inflation lumen 108 is shown within the body of the sheath.
  • a proximal end of a guide wire 110 is first inserted into the vein to be treated up to the selected treatment site.
  • the device is then threaded onto a distal end of the guide wire so that the guide wire passes through the central bore 103.
  • the device is then inserted into the vessel along the guide wire.
  • the guide wire 110 is introduced inside the vein to be treated with the aid of an introducer needle or similar.
  • the treatment is advantageously performed with the aid of a viewing or imaging scope, preferably under ultrasound guidance.
  • the procedure is carried out entirely under ultrasound guidance in order to monitor progress inside the blood vessel and check appropriate positioning inside blood vessel lumen.
  • inflatable member 104 When the tip of the sheath 102 is positioned in the section of the vein to be treated, inflatable member 104 is inflated by supplying pressurized inflation fluid through the inflation lumen 108 until its surface reaches vein wall 106, as shown in Figure 1. Once inflatable member 104 is in contact with vessel wall 106, the medical practitioner withdraws sheath 102. Due to the roughened surface of the inflatable member, a preselected section of the vessel wall is damaged and the vessel collapses. In order to enhance the damaging effect to the vessel wall, the hollow tube may be moved back and forth, rotated or moved in other manners while it is withdrawn. The tip of the sheath may have a round tip that cannot damage the vessel wall while it enters and follows the blood vessel up to the preselected treatment site.
  • the present invention provides minimally invasive methods and medical devices for safe and efficient endoluminal treatment of veins in mammals.
  • a key feature of present invention is the possibility of endoluminally treating blood vessels in a simple manner avoiding the complexity and possible undesired side effects of prior art devices and techniques.
  • One of the main advantages of present invention is that the treatment can be performed as an outpatient procedure without needing general anesthesia, significantly diminishing the risks associated with prior art procedures.
  • the lumens of blood vessels are endoluminally damaged, reducing its diameter sufficiently to avoid the pathological reflux in the diseased veins. While the treatment is performed, the damaged blood vessel collapses due to a vasospasm producing the desired permanent diameter reduction and/or closure of the vessels.
  • the described treatment may be carried out in conjunction with other treatments.
  • a fibre optic cable may be passed through the central bore to the treatment site so that laser treatment can be applied to the vessel.
  • This may complement the mechanical treatment provided by the roughened surface and may be useful for larger vessels in particular.
  • the additional mechanical treatment may allow thermal treatment to be effective at lower power, meaning less pain for the patient and avoiding the need for general anesthesia.
  • a radio frequency treatment device may be passed through the central bore to allow radio frequency treatment to be carried out together with the mechanical treatment.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medical Informatics (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Surgical Instruments (AREA)

Abstract

L'invention concerne un dispositif médical faiblement invasif permettant le traitement endoluminal sûr et efficace de veines chez des mammifères. Dans un mode de réalisation préféré, un dispositif médical pour traiter des troubles vasculaires comprend une gaine creuse (102) et un élément expansible (104) pourvu d'une surface rugueuse et d'une longueur variable couplé à une extrémité proximale de la gaine creuse.
PCT/GB2014/052378 2013-08-02 2014-08-04 Dispositif faiblement invasif et méthode pour traiter des troubles vasculaires WO2015015226A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1313843.3 2013-08-02
GB1313843.3A GB2519057A (en) 2013-08-02 2013-08-02 Minimally invasive device and method for treating vascular disorders

Publications (1)

Publication Number Publication Date
WO2015015226A1 true WO2015015226A1 (fr) 2015-02-05

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PCT/GB2014/052378 WO2015015226A1 (fr) 2013-08-02 2014-08-04 Dispositif faiblement invasif et méthode pour traiter des troubles vasculaires

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WO (1) WO2015015226A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108784758A (zh) * 2018-04-08 2018-11-13 河北北方学院附属第医院 一种三腔二囊管式静脉剥脱器及其使用方法

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3095704A1 (fr) 2018-05-18 2019-11-21 National University Of Ireland, Galway Dispositif pour denuder une lumiere corporelle

Citations (3)

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Publication number Priority date Publication date Assignee Title
US20090270787A1 (en) * 2008-04-23 2009-10-29 Abbott Cardiovascular Systems Inc. Systems and methods for creating enlarged migration channels for therapeutic agents within the endothelium
WO2011097229A2 (fr) * 2010-02-02 2011-08-11 Levitronix Llc Dispositif médical extensible et pliable
US20130096604A1 (en) * 2011-10-18 2013-04-18 Boston Scientific Scimed, Inc. Integrated crossing balloon catheter

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US5100425A (en) * 1989-09-14 1992-03-31 Medintec R&D Limited Partnership Expandable transluminal atherectomy catheter system and method for the treatment of arterial stenoses
EP0596928B1 (fr) * 1991-07-15 2000-04-05 ZACCA, Nadim M. Appareil d'atherectomie et d'angioplastie
US6096054A (en) * 1998-03-05 2000-08-01 Scimed Life Systems, Inc. Expandable atherectomy burr and method of ablating an occlusion from a patient's blood vessel
US6451037B1 (en) * 2000-11-22 2002-09-17 Scimed Life Systems, Inc. Expandable atherectomy burr with metal reinforcement
US20050240148A1 (en) * 2004-04-21 2005-10-27 Scimed Life Systems, Inc. Traction cutting balloon
US20080077164A1 (en) * 2006-02-24 2008-03-27 National University Of Ireland, Galway Minimally Invasive Intravascular Treatment Device

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090270787A1 (en) * 2008-04-23 2009-10-29 Abbott Cardiovascular Systems Inc. Systems and methods for creating enlarged migration channels for therapeutic agents within the endothelium
WO2011097229A2 (fr) * 2010-02-02 2011-08-11 Levitronix Llc Dispositif médical extensible et pliable
US20130096604A1 (en) * 2011-10-18 2013-04-18 Boston Scientific Scimed, Inc. Integrated crossing balloon catheter

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108784758A (zh) * 2018-04-08 2018-11-13 河北北方学院附属第医院 一种三腔二囊管式静脉剥脱器及其使用方法

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GB201313843D0 (en) 2013-09-18

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