WO2014207532A1 - Positive-displacement micropump - Google Patents

Positive-displacement micropump Download PDF

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Publication number
WO2014207532A1
WO2014207532A1 PCT/IB2014/001149 IB2014001149W WO2014207532A1 WO 2014207532 A1 WO2014207532 A1 WO 2014207532A1 IB 2014001149 W IB2014001149 W IB 2014001149W WO 2014207532 A1 WO2014207532 A1 WO 2014207532A1
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WO
WIPO (PCT)
Prior art keywords
pump according
pump
piston
pistons
whose
Prior art date
Application number
PCT/IB2014/001149
Other languages
French (fr)
Inventor
Florent Junod
Thierry Navarro
Original Assignee
Swissinnov Product Sarl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Swissinnov Product Sarl filed Critical Swissinnov Product Sarl
Publication of WO2014207532A1 publication Critical patent/WO2014207532A1/en

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Classifications

    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04BPOSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B7/00Piston machines or pumps characterised by having positively-driven valving
    • F04B7/04Piston machines or pumps characterised by having positively-driven valving in which the valving is performed by pistons and cylinders coacting to open and close intake or outlet ports
    • F04B7/045Two pistons coacting within one cylinder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/14212Pumping with an aspiration and an expulsion action
    • A61M5/14216Reciprocating piston type
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/14244Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04BPOSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B3/00Machines or pumps with pistons coacting within one cylinder, e.g. multi-stage
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04BPOSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B9/00Piston machines or pumps characterised by the driving or driven means to or from their working members
    • F04B9/02Piston machines or pumps characterised by the driving or driven means to or from their working members the means being mechanical
    • F04B9/04Piston machines or pumps characterised by the driving or driven means to or from their working members the means being mechanical the means being cams, eccentrics or pin-and-slot mechanisms
    • F04B9/045Piston machines or pumps characterised by the driving or driven means to or from their working members the means being mechanical the means being cams, eccentrics or pin-and-slot mechanisms the means being eccentrics
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04CROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT PUMPS
    • F04C2/00Rotary-piston machines or pumps
    • F04C2/02Rotary-piston machines or pumps of arcuate-engagement type, i.e. with circular translatory movement of co-operating members, each member having the same number of teeth or tooth-equivalents
    • F04C2/063Rotary-piston machines or pumps of arcuate-engagement type, i.e. with circular translatory movement of co-operating members, each member having the same number of teeth or tooth-equivalents with coaxially-mounted members having continuously-changing circumferential spacing between them
    • F04C2/07Rotary-piston machines or pumps of arcuate-engagement type, i.e. with circular translatory movement of co-operating members, each member having the same number of teeth or tooth-equivalents with coaxially-mounted members having continuously-changing circumferential spacing between them having crankshaft-and-connecting-rod type drive

Definitions

  • the invention relates to a compact miniature displacement pump consisting of at least two reciprocating pistons for the precise and variable dispensing of liquid, medicine, food, detergent, cosmetic product, chemical compound. or any other type of fluid, gel or gas.
  • the present invention relates to a high performance micro pump composed of two reciprocating pistons with a simple drive system.
  • the pump includes at least two pistons, in opposition, placed in at least one cavity, preferably cylindrical and circular, possibly in the form of a torus, a pump body with at least one input port and at least one output port, being in connection with at least one pumping chamber formed by the ends of the pistons and the cavity.
  • the pistons are preferably driven directly on their body by eccentric pin fixed to the rotor of an actuator preferably in the form of a motor.
  • the principle of pumping consists of driving at least one piston so as to successively open / fill at least one pumping chamber when it is connected to at least one inlet port, then to move the chamber filled with fluid, between the input and output ports, and close / empty the chamber when it is connected with at least one output port.
  • the pump lends itself well to the dosage of micro volumes and the realization of implantable device or patch disposed on the body requiring a small footprint.
  • the pump is particularly well suited for low cost production since it is mainly made of easily injectable plastic parts and can be assembled automatically.
  • Figure 1 is an overview of the pump without the upper pump body
  • Figure 2 is a side view of the pump
  • Figure 3a is a top view of the pump
  • Figure 3b is a bottom view of the pump
  • FIG. 4 is an overview of the exploded pump
  • FIG. 5a is a longitudinal section along the line A-A of FIG. 2 during the first pumping phase.
  • FIG. 5b is a longitudinal section along the line B-B of FIG. 2 during the first pumping phase
  • FIG. 5c is a longitudinal section along line C-C of FIG. 3a during the first pumping phase
  • FIG. 6a is a longitudinal section along the line A-A of FIG. 2 during the second pumping phase
  • FIG. 6b is a longitudinal section along the line B-B of FIG. 2 during the second pumping phase
  • FIG. 6c is a longitudinal section along line C-C of FIG. 3a during the second pumping phase
  • FIG. 7a is a longitudinal section along the line A-A of FIG. 2 during the third pumping phase
  • FIG. 7b is a longitudinal section along line B-B of FIG. 2 during the third pumping phase
  • FIG. 7c is a longitudinal section along line C-C of FIG. 3a during the third pumping phase
  • FIG. 8a is a longitudinal section along line AA of FIG. 2 during the fourth pumping phase
  • FIG. 8b is a longitudinal section along line BB of FIG. 2 during the fourth pumping phase
  • FIG. 8c is a longitudinal section along line C-C of FIG. 3a during the fourth pumping phase
  • FIG. 9 is a view of a second embodiment of the invention.
  • FIG. 10 is a view from above of the second embodiment
  • FIG. 11 is a longitudinal section along the line A-A of FIG.
  • FIG. 12 is a side view of the second embodiment
  • FIG. 13 is a longitudinal section along line B-B of FIG. 12
  • FIG. 14 is a perspective view from above of a third embodiment of the invention.
  • FIG. 15 is a bottom perspective view of the third embodiment.
  • FIG. 1 is a side view of the third embodiment.
  • FIG. 17 is a view from above of the third mode of execution
  • FIG. 18 is a longitudinal section along the line A-A of FIG.
  • FIG. 19a is a view from above of the first pumping phase of the third embodiment.
  • FIG. 19 is a longitudinal section along the line C-C of FIG.
  • FIG. 20a is a view from above of the second pump phase of the third embodiment
  • Figure 20b a longitudinal section along the line C-C of Figure 20a
  • FIG. 21a is a view from above of the third pump phase of the third embodiment
  • FIG. 22a is a view from above of the fourth pump phase of the third embodiment
  • FIG. 22b is a longitudinal section along line C-C of FIG. 22a;
  • FIG. 23 is a perspective view from above of a fourth embodiment of the invention.
  • FIG. 24 is a perspective view from above of the fourth embodiment of the invention in transparency
  • FIG. 25 is a side view of the fourth embodiment
  • FIG. 26 is a front view of the fourth embodiment
  • FIG. 27 is a longitudinal section along the line A-A of Figure 25
  • FIG. 28 is a longitudinal section along line BB of Fig. 26
  • Fig. 29 is an overview of a fifth embodiment of the invention
  • Fig. 30 is an overview of the fifth embodiment of Figs. transparent execution
  • FIG. 31 is a top view of the fifth embodiment
  • the pump (I) consists of an upper pump body (2 ') and a lower pump body (2) each having a half cavity respectively ( 2, 21) forming a toroidal cavity (22), preferably of circular section, when the two upper and lower pump bodies (2 ', 2) are joined together.
  • a drive member (30) is comprised of a rotor (10) having an eccentric axis (12) extending through an opening (16), preferably in the form of an oblong, located on the piston (3) so as to being able to rotate on the supports (14, 14 ') at the ends of the drive (30).
  • the guide element (1 1) preferably in the form of a bearing or a bearing, is optionally placed around the eccentric axis (1 2) so as to be housed in the opening (40) situated between both ends of the piston (3), so as to drive the piston (3) during the rotation of the drive member (30) by an actuator, preferably in the form of a motor not shown.
  • the piston (3) is preferably arcuate and preferably consists of four grooves (17, 17 ', 17 ", 17'") in which sealing elements (23 and 23 ', 23 ", 23'” illustrated), preferably in the form of O-rings or specific seals.
  • the preferably arcuate piston (4) preferably consists of two grooves (20, 20 ') in which sealing elements (23 "" and 23 ""', not shown) are housed, preferably in the form of O-rings. -rings or specific joints.
  • the ends of the pistons (3,4) are preferably composed of notches (18, 18 ', 19, 19') so as to form a small gap when the pins (3,4) are in contact to facilitate the passage fluid between the pumping chambers (31, 32) and the inlet and outlet ports (5, 5 ', 6, 6').
  • the two pistons (3, 4) are placed inside the cavity so as to form two pumping chambers (3 1, 32), each located on both sides of the cavity. other ends of the pistons (3,4), in connection alternately with the input ports (5,5 ') and the output ports (6,6').
  • the sealing elements (23,23 ', 23 ", 23" ⁇ 23 "", 23 “"') seal between the input ports (5,5 ') and the output ports (6, 6 ').
  • the output ports (6, 6 ') are connected to an output channel (7).
  • the input ports (5, 5 ') are connected to a reservoir or a common input channel that is not shown.
  • the 360 ° rotation of the rotor (10) has the effect of displacing the piston (3) alternately, which corresponds to a complete pumping cycle.
  • the successive phases of the pumping cycle are composed as follows: according to FIG. 5a, when the piston (3) is resting on the piston (4), the pumping chamber (3 1) is open and in connection with the output port (6). The pumping chamber (32) is closed and in connection with the input port (5 '), the rotor (10) is in position 0.
  • the pump (101) consists of two pump bodies (102, 102 ') each having a cavity (122, 122') preferably in the form of a circular hole, placed facing each other so as to form two chambers pumping (131,132) when the pistons (103,104) are placed in the cavities (122,122 ').
  • the pistons (103, 103 ') are preferably formed of a support (160) having at least a portion surrounding the pump bodies (102, 102') and for placing the ends of the piston (104) in opposition to the pistons (103, 103 ' ) so as to form the two pumping chambers (131, 132).
  • the cavities (122,122 ') are preferably opposite coaxial and linear.
  • the input (105,105 ') and output (106,106') ports are placed on the pump bodies (102,102 ') so as to be connected to the pump chambers (131,132).
  • the input (105,105 ') and output (106,106') ports may be communicating respectively in the two pump bodies (102,102 ').
  • Two guide members (111, 111 '), preferably in the form of bearings or bearings, are placed on an eccentric pin (112) on a rotor (110) attached to an actuator (150), preferably in the form of a motor.
  • the guide member (111 ') is placed in the opening (140), preferably in the form of an oblong, located on the support (160) between the pistons (103, 103') so as to displace the pistons (103). , 103 ') during rotation of the rotor (110).
  • the guide member (111) is placed in the opening (116) between the two ends of the piston (104) so as to move the piston (104) during rotation of the rotor (110).
  • the opening (116) is preferably in the form of an oblong having a specific profile, including spokes (170, 170 ') on the faces perpendicular to the axis of the piston (104) and having a space (116') with (III) calculated to drive and control the piston (104) in delay / offset with the movement of the pistons (103, 103 ') to achieve the same pumping sequences as previously described in the first variant of the invention.
  • the sealing elements (123 and other unnumbered) placed on the pistons (103, 103 ', 104) are preferably in the form of O-rings.
  • the angular displacements of the rotor element (10, 1 10), corresponding to the pumping phases, are given as an indication and can be adapted according to the geometry and the size of the pump.
  • the guide elements (1 1 1, 1 1 1 ') can be formed by a single guide element (1 1 1) placed in the two openings (1 1 6, 140).
  • the pump (201) consists of a pump body (202) having a cavity (222) preferably in the form of a cylindrical hole forming a pumping chamber (231). ) when the pistons (203,204) are placed in the cavity (222).
  • the input port (205) and the output port (206) are placed on the pump body (202) so as to be connected to the pump chamber (231).
  • Two guide elements (21 1, 21 1 '), preferably in the form of bearings or bearings, are placed on an eccentric axis (212) located on a rotor (210) fixed to an actuator (250), preferably in the form of a motor.
  • the guide element (21 ⁇ ) is placed in the opening (240), preferably in oblong form, on the support (260) at one end of the piston (203) so as to move the piston linearly ( 203) along its axis during rotation of the rotor (2 1 0).
  • the guide member (21 1) is placed in the opening (216) at one end of the piston (204) so as to linearly move the piston (204) along its axis during rotation of the rotor (210).
  • the openings (216, 240) are preferably in the form of oblong.
  • the opening (216) is preferably in the form of a oblong, having a specific profile, comprising spokes (270,270 ') on the faces perpendicular to the axis of the piston (204) and having a space (216') with the guide element (21 1) calculated so as to cause and controlling the piston (204) in delay / offset with the movement of the piston (203) to perform the pumping sequences similar to the previously described variants.
  • the 360 ° rotation of the rotor (210) has the effect of moving the pistons (203, 204) alternately, which corresponds to a complete pumping cycle.
  • the successive phases of the pumping cycle are composed as follows: according to FIGS. 22a and 22b, when the piston (203) bears on the piston (204), the pumping chamber (23 1) is closed and connected with the output port (6). The rotor (210) is in position 0.
  • FIGS. 19a and 19b when the rotor (2 1 0) rotates from 0 to 120 °, the piston (204) moves in the forward direction and presses on the piston (203) so as to move and close it / empty the pumping chamber (23 1).
  • the pumping chamber (23 1) moves to the input port (205) while remaining closed.
  • the piston (204) when the rotor (210) rotates from 120 ° to 210 °, the piston (204) moves in the return direction which has the effect of opening the chamber (23 1) and to suck the fluid in the chamber (23 1) from the inlet port (205).
  • the piston (203) remains in a fixed position during a portion of the displacement of the piston (204).
  • the seal members (223 and other unnumbered) on the pistons (203, 204) are preferably in the form of O-rings.
  • the guide elements (21 1, 21 ⁇ ) can be formed by a single guide element (21 1) placed in the two openings (216,240).
  • the pump (301) consists of a pump body (302) having a cavity (322) preferably in the form of a circular hole forming a pumping chamber (33 1) when the pistons (303,304 ) are placed in the cavity (322).
  • the input port (305) and the output port (306) are placed on the pump body (302) so as to be connected to the pump chamber (33 1).
  • a guide element (3 1 1) preferably in the form of a bearing or a bearing, is placed on an eccentric axis (3 1 2) located on a rotor (3 10) fixed to an actuator (350), preferably in the form of a a motor.
  • the guide element (3 1 1) is placed in the opening (340), preferably in the form of an oblong, located on a drive support (360), now preferably the piston (303) via a pin or pin (353) fixed (e) to the drive carrier (360), so as to move lamentarily the piston (303) along its axis during the rotation of the rotor (3 10).
  • a second pin or pin (354) attached to the drive carrier (360) is placed in an opening (3 1 6) at one end of the piston (304) to move the piston linearly ( 304) along its axis during the rotation of the rotor (3 10).
  • the opening (316) is preferably in the form of an oblong, thus having a space (316 ') with the axis or pin (354) calculated to drive and control the piston (304) in delay / offset with the movement of the piston (303) to perform the pumping sequences similar to the previously described variants.
  • the actuator (350), the rotor (3 10) and the drive carrier are preferably attached to a pump mount (352) so as to be able to receive the pump body (302) as a removable member.
  • Seals (323 and other unnumbered) placed on the pistons (303, 304) are preferably in the form of O-rings.
  • the pump (401) consists of a pump body (402) having a cavity (422) preferably in the form of a cylindrical hole forming a pumping chamber (43 1) when the pistons (403, 404) are placed in the cavity (422).
  • the piston 404 is controlled by a control axis (480) coaxial with the piston (403). Sealing between the control shaft (480) and the piston (403) is provided by a seal (425), preferably in the form of an O-ring.
  • the input port (405) and the output port (406) are placed on the pump body (402) so as to be alternately connected to the pumping chamber (431) according to the position of the pistons (403, 404).
  • the eccentric axis (41 2) is placed in the openings (416,440), preferably in the form of oblongs having a specific profile, including spokes (470,470 ') on the faces perpendicular to the piston axis (404) and having a space (416) with the eccentric axis (412), of in such a way that the pistons (404, 403) are respectively displaced axially during the rotation of the rotor (410).
  • the axis profile (4 12) preferably corresponds to a three-lobe cam, and a space (416) is calculated to drive and control the piston (404) late / offset with the movement of the piston (403). to perform the pumping sequences similar to the previously described variants.
  • the three-lobe cam and the rounded (490,490 ') allow the piston (404) to be moved in a controlled and play-free manner independently of the friction due to the seal (425) between the control shaft (480) and the piston (404). ).
  • the piston (403) is preferably hollow so as to receive the control shaft (480) of the piston (404) and form a part of the pumping chamber (43 1) by the difference of the diameters of the pistons (403, 404), thereby reducing the tai l of the system.
  • Seals (423 and other unnumbered) on the pistons (403, 404) are preferably in the form of O-rings.
  • the cavities (122, 122 ') may be eccentric parallel so as to reduce the size of the pump.
  • the cavity (22) can be made in the form of a hollow torus placed on one of the pump bodies (2, 2 ').
  • the actuator may be in the form of any electromechanical system converting electrical energy into a mechanical movement operating the rotor.
  • the actuator may be adapted to actuate the rotor in a non-continuous sequential motion such as an electromagnet.
  • the rotor movement can then be controlled from so as to realize all or part of the pumping sequence during actuation of the actuator so as to deluge predefined doses of fluid commonly called "bolus".
  • the reservoir of the pump can be integrated with one of the pump bodies so as to reduce the size of the pump and the container containing the fluid to be pumped.
  • the reservoir may be, for example, in the form of a cylinder with a removable cap / piston or a flexible pouch.
  • the tank may be pre-filled so as to form with the pump body a removable assembly for a single use in the form of cartridge housed on a durable element comprising all or part of the guide element, all or part of the rotor and all or part of the actuator.
  • the actuator can be made in the form of a mechanical actuator without a motor such as a spring-loaded movement or a manually actuated drive such as a pushbutton, a pawl, a trigger or any other mechanism driving the actuator. rotor or guide element.
  • This type of drive without motor makes it possible, for example, to produce a patch pump mounted on the body or a portable disposable pump for continuously dispensing medication or manual dosing without an electronic element or battery.
  • This variant can also consist of an integrated reservoir, which itself can be pre-filled.
  • the sealing between the moving parts is preferably achieved by an elastomer, an overmolded seal or any other sealing element.
  • an elastomer elastomer
  • an overmolded seal elastomer
  • any other sealing element elastomer
  • This type of adjustment can be made of ceramic or metal parts commonly used in seamless pumps.
  • the elements constituting the pump are preferably plastic and disposable.
  • the pump can be sterilized for dispensing food or medicine for example. The choice of materials, however, is not limited to plastics.
  • sensors or sensor elements to one or several components of the pump in order to measure and / or control various parameters related to its use, such as for example: the temperature, the pressure of the pumped fluid, ambient humidity, vibration, movement or position of moving parts.

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  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • Reciprocating Pumps (AREA)

Abstract

The invention relates to a pump comprising: at least two pistons (3, 4) placed in at least one cavity (22) located in at least one pump body (2, 2'), forming at least one pumping chamber (31, 32) located on each side of the ends of the pistons (3, 4) and alternately connected to at least one inlet port (5, 5') and at least one outlet port (6, 6') located in the pump body (2, 2'); and at least one guiding element (11) secured to an eccentric shaft (12) of a rotor (10), moving at least one piston (3, 4) such as to successively fill at least one pumping chamber (31, 32) when said chamber is connected to at least one inlet port (5, 5') and then to move the fluid-filled chamber (31, 32) between the inlet and outlet ports (5, 5', 6, 6') and empty the chamber (31, 32) when it is connected to at least one outlet port (6, 6').

Description

MICRO POMPE VOLUMETRIOUE  MICRO PUMP VOLUMETRIQUE
L' invention concerne une pompe volumétrique miniature à faible encombrement constituée d'au moins deux pistons à mouvement alternati f pour la distribution précise et à débit variable de liquide, de médicament, d'aliment, de détergent, de produit cosmétique, de composé chimique ou tout autre type de fluide, gel ou gaz. The invention relates to a compact miniature displacement pump consisting of at least two reciprocating pistons for the precise and variable dispensing of liquid, medicine, food, detergent, cosmetic product, chemical compound. or any other type of fluid, gel or gas.
L'art antérieur The prior art
Il existe différents types de pompes volumétriques à pistons alternatifs tels que décrits dans les brevets US5639220, US 15 16032, GB 157692 dont le principe consiste à actionner deux pistons linéaires en opposition pour déplacer le l iquide entre les ports d 'entrée et sortie de la pompe. Ces systèmes actionnent les pistons par des éléments mécaniques complexes placés à l'extérieur des pistons ce qui les rend inadaptés pour la réal isation de micro pompe de dosage pour des systèmes implantables ou placés sur le corps car leur encombrement est trop important. De plus le nombre de pièces constituant ces systèmes est élevé, ce qui rend leur coût de fabrication trop cher. There are various types of reciprocating piston positive displacement pumps as described in US5639220, US 16032, GB 157692, the principle of which is to actuate two opposing linear pistons to move the liquid between the inlet and outlet ports of the piston. pump. These systems actuate the pistons by complex mechanical elements placed outside the pistons which makes them unsuitable for the realization of micro dosing pump for implantable systems or placed on the body because their size is too important. In addition the number of parts constituting these systems is high, which makes their manufacturing cost too expensive.
Description de l'invention Description of the invention
La présente invention concerne une micro pompe performante composée de deux pistons alternatifs avec un système d'entraînement simple. The present invention relates to a high performance micro pump composed of two reciprocating pistons with a simple drive system.
Cette invention résout les problèmes exposés précédemment et permet une mise au point simplifiée pour la production à très grande échel le de pompes avec un élément en contact avec le fluide pompé préférablement en plastique jetables bon marché. La pompe comprend au moins deux pistons, en opposition, placés dans au moins une cavité, préférablement cylindrique et circulaire, possiblement sous la forme d'un tore, d 'un corps de pompe avec au moins un port d'entrée et au moins un port de sortie, étant en liaison avec au moins une chambre de pompage formée par les extrémités des pistons et la cavité. Les pistons sont préférablement entraînés directement sur leur corps par axe excentrique fixé sur le rotor d'un actuateur préférablement sous la forme d'un moteur. Le principe de pompage consiste à entraîner au moins un piston de manière à successivement ouvrir/rempl ir au moins une chambre de pompage lorsque celle-ci est en liaison avec au moins un port d'entrée, puis de déplacer la chambre remplie de fluide, entre les ports d'entrée et sortie, et fermer/vider la chambre lorsque celle-ci est en liaison avec au moins un port de sortie. This invention solves the problems discussed above and allows for simplified tuning for very large scale production of pumps with an element in contact with the pumped fluid preferably in inexpensive disposable plastics. The pump includes at least two pistons, in opposition, placed in at least one cavity, preferably cylindrical and circular, possibly in the form of a torus, a pump body with at least one input port and at least one output port, being in connection with at least one pumping chamber formed by the ends of the pistons and the cavity. The pistons are preferably driven directly on their body by eccentric pin fixed to the rotor of an actuator preferably in the form of a motor. The principle of pumping consists of driving at least one piston so as to successively open / fill at least one pumping chamber when it is connected to at least one inlet port, then to move the chamber filled with fluid, between the input and output ports, and close / empty the chamber when it is connected with at least one output port.
La pompe se prête bien au dosage de micro volumes et la réalisation de dispositif implantable ou patch disposé sur le corps nécessitant un faible encombrement. The pump lends itself well to the dosage of micro volumes and the realization of implantable device or patch disposed on the body requiring a small footprint.
La pompe est particul ièrement bien adaptée pour une production à faible coût étant donné qu'elle est formée principalement de pièces facilement injectables en plastique et assemblables automatiquement. The pump is particularly well suited for low cost production since it is mainly made of easily injectable plastic parts and can be assembled automatically.
Description des dessins Description of the drawings
La présente invention sera mieux comprise à la lecture de la description des exemples donnés, à titre purement indicatif et nullement l imitatif, en faisant référence aux dessins annexés sur lesquels : The present invention will be better understood on reading the description of the examples given, purely for illustrative purposes and in no way imitative, with reference to the appended drawings in which:
La figure 1 est une vue d 'ensemble de la pompe sans le corps de pompe supérieur La figure 2 est une vue de côté de la pompe Figure 1 is an overview of the pump without the upper pump body Figure 2 is a side view of the pump
La figure 3a est une vue de dessus de la pompe Figure 3a is a top view of the pump
La figure 3b est une vue de dessous de la pompe Figure 3b is a bottom view of the pump
La figure 4 est d'ensemble de la pompe en éclaté Figure 4 is an overview of the exploded pump
La figure 5a est une coupe longitudinale selon la l igne A-A de la figure 2 lors de la première phase de pompage  FIG. 5a is a longitudinal section along the line A-A of FIG. 2 during the first pumping phase.
La figure 5b est une coupe longitudinale selon la ligne B-B de la figure 2 lors de la première phase de pompage  FIG. 5b is a longitudinal section along the line B-B of FIG. 2 during the first pumping phase
La figure 5c est une coupe longitudinale selon la ligne C-C de la figure 3a lors de la première phase de pompage  FIG. 5c is a longitudinal section along line C-C of FIG. 3a during the first pumping phase
La figure 6a est une coupe longitudinale selon la ligne A-A de la figure 2 lors de la seconde phase de pompage  FIG. 6a is a longitudinal section along the line A-A of FIG. 2 during the second pumping phase
La figure 6b est une coupe longitudinale selon la ligne B-B de la figure 2 lors de la seconde phase de pompage  FIG. 6b is a longitudinal section along the line B-B of FIG. 2 during the second pumping phase
La figure 6c est une coupe longitudinale selon la ligne C-C de la figure 3a lors de la seconde phase de pompage  FIG. 6c is a longitudinal section along line C-C of FIG. 3a during the second pumping phase
La figure 7a est une coupe longitudinale selon la ligne A-A de la figure 2 lors de la troisième phase de pompage  FIG. 7a is a longitudinal section along the line A-A of FIG. 2 during the third pumping phase
La figure 7b est une coupe longitudinale selon la ligne B-B de la figure 2 lors de la troisième phase de pompage  FIG. 7b is a longitudinal section along line B-B of FIG. 2 during the third pumping phase
La figure 7c est une coupe longitudinale selon la ligne C-C de la figure 3a lors de la troisième phase de pompage  FIG. 7c is a longitudinal section along line C-C of FIG. 3a during the third pumping phase
La figure 8a est une coupe longitudinale selon la l igne A-A de la figure 2 lors de la quatrième phase de pompage La figure 8b est une coupe longitudinale selon la ligne B-B de la figure 2 lors de la quatrième phase de pompage FIG. 8a is a longitudinal section along line AA of FIG. 2 during the fourth pumping phase FIG. 8b is a longitudinal section along line BB of FIG. 2 during the fourth pumping phase
La figure 8c est une coupe longitudinale selon la ligne C-C de la figure 3a lors de la quatrième phase de pompage  FIG. 8c is a longitudinal section along line C-C of FIG. 3a during the fourth pumping phase
- La figure 9 est une vue d'un second mode d'exécution de l ' invention FIG. 9 is a view of a second embodiment of the invention
La figure 10 est une vue de dessus du second mode d'exécution  FIG. 10 is a view from above of the second embodiment
La figure 1 1 est une coupe longitudinale selon la l igne A-A de la figure 1 0  FIG. 11 is a longitudinal section along the line A-A of FIG.
La figure 1 2 est une vue de côté du second mode d'exécution  FIG. 12 is a side view of the second embodiment
- La figure 13 est une coupe longitudinale selon la ligne B-B de la figure 12 FIG. 13 is a longitudinal section along line B-B of FIG. 12
- La figure 14 est une vue en perspective de dessus d'un troisième mode d'exécution de l'invention FIG. 14 is a perspective view from above of a third embodiment of the invention
La figure 1 5 est une vue en perspective de dessous du troisième mode d'exécution La figure 1 6 est une vue de côté du troisième mode d'exécution  FIG. 15 is a bottom perspective view of the third embodiment. FIG. 1 is a side view of the third embodiment.
La figure 17 est une vue de dessus du troisième mode d'exécution  FIG. 17 is a view from above of the third mode of execution
- La figure 18 est une coupe longitudinale selon la l igne A-A de la figure 1 7 FIG. 18 is a longitudinal section along the line A-A of FIG.
La figure 19a est un vue de dessus de la prem ière phase de pompage du troisième mode d'exécution  FIG. 19a is a view from above of the first pumping phase of the third embodiment.
La figure 1 9b une coupe longitudinale selon la ligne C-C de la figure 1 a  FIG. 19 is a longitudinal section along the line C-C of FIG.
La figure 20a est un vue de dessus de la deuxième phase de pompage du troisième mode d'exécution  FIG. 20a is a view from above of the second pump phase of the third embodiment
La figure 20b une coupe longitudinale selon la ligne C-C de la figure 20a  Figure 20b a longitudinal section along the line C-C of Figure 20a
La figure 21 a est un vue de dessus de la troisième phase de pompage du troisième mode d'exécution  FIG. 21a is a view from above of the third pump phase of the third embodiment
La figure 2 1 b une coupe longitudinale selon la l igne C-C de la figure 21 a La figure 22a est un vue de dessus de la quatrième phase de pompage du troisième mode d'exécution Figure 2 1b a longitudinal section along the line CC of Figure 21a FIG. 22a is a view from above of the fourth pump phase of the third embodiment
La figure 22b une coupe longitudinale selon la ligne C-C de la figure 22a La figure 23 est une vue en perspective de dessus d'un quatrième mode d'exécution de l' invention  FIG. 22b is a longitudinal section along line C-C of FIG. 22a; FIG. 23 is a perspective view from above of a fourth embodiment of the invention;
La figure 24 est une vue en perspective de dessus du quatrième mode d'exécution de l'invention en transparence  FIG. 24 is a perspective view from above of the fourth embodiment of the invention in transparency
La figure 25 est une vue de côté du quatrième mode d'exécution  FIG. 25 is a side view of the fourth embodiment
La figure 26 est une vue de face du quatrième mode d'exécution  FIG. 26 is a front view of the fourth embodiment
- La figure 27 est une coupe longitudinale selon la ligne A-A de la figure 25  - Figure 27 is a longitudinal section along the line A-A of Figure 25
La figure 28 est une coupe longitudinale selon la ligne B-B de la figure 26 La figure 29 est une vue d'ensemble d'un cinquième mode d'exécution de l' invention La figure 30 est une vue d'ensemble du cinquième mode d'exécution en transparence La figure 31 est une vue de dessus du cinquième mode d'exécution  Fig. 28 is a longitudinal section along line BB of Fig. 26 Fig. 29 is an overview of a fifth embodiment of the invention Fig. 30 is an overview of the fifth embodiment of Figs. transparent execution FIG. 31 is a top view of the fifth embodiment
- La figure 32 est une coupe longitudinale selon la l igne A-A de la figure 3 1  32 is a longitudinal section along the line A-A of FIG.
Selon les figures 1 , 2, 3b, 4 et 5c, la pompe ( I ) se compose d'un corps de pompe supérieur (2') et d'un corps de pompe inférieur (2) ayant chacun respectivement une demi-cavité (2 ,21) circulaire formant une cavité (22) en forme de tore, préférablement de section circulaire, lorsque les deux corps de pompe supérieur et inférieur (2',2) sont joints l'un avec l'autre. Un élément d'entraînement (30) se compose d'un rotor ( 10) ayant un axe excentré ( 12) traversant une ouverture ( 16), préférablement sous la forme d'un oblong, situé sur le piston (3) de manière à pouvoir tourner en appui sur les supports ( 14, 14') aux extrémités de l'entraînement (30). Un élément de guidage ( 1 1 ), préférablement sous la forme d'un palier ou d'un roulement, est optionnellement placé autour de l 'axe excentré ( 1 2) de manière à se loger dans l 'ouverture (40), située entre les deux extrémités du piston (3), de manière à entraîner le piston (3) lors de la rotation de l'élément d'entraînement (30) par un actuateur, préférablement sous la forme d'un moteur non représenté. Le piston (3) préférablement arqué, se compose préférablement de quatre rainures ( 17, 17', 17", 17' ") dans lesquelles viennent se loger des éléments d'étanchéité (23 et 23',23",23' " non illustrés), préférablement sous la forme de joints O-rings ou joints spécifiques. Le piston (4) préférablement arqué, se compose préférablement de deux rainures (20,20') dans lesquelles viennent se loger des éléments d'étanchéité (23"" et 23"" ' non illustrés), préférablement sous la forme de joints O-rings ou joints spécifiques. Les extrémités des pistons (3,4) se composent préférablement d'encoches ( 18, 1 8', 19, 19') de manière à former un petit espace lorsque les pisons (3,4) sont en contact afin de faciliter le passage du fluide entre les chambres de pompage (3 1 ,32) et les ports d'entrée et sortie (5, 5 ', 6,6'). According to FIGS. 1, 2, 3b, 4 and 5c, the pump (I) consists of an upper pump body (2 ') and a lower pump body (2) each having a half cavity respectively ( 2, 21) forming a toroidal cavity (22), preferably of circular section, when the two upper and lower pump bodies (2 ', 2) are joined together. A drive member (30) is comprised of a rotor (10) having an eccentric axis (12) extending through an opening (16), preferably in the form of an oblong, located on the piston (3) so as to being able to rotate on the supports (14, 14 ') at the ends of the drive (30). A The guide element (1 1), preferably in the form of a bearing or a bearing, is optionally placed around the eccentric axis (1 2) so as to be housed in the opening (40) situated between both ends of the piston (3), so as to drive the piston (3) during the rotation of the drive member (30) by an actuator, preferably in the form of a motor not shown. The piston (3) is preferably arcuate and preferably consists of four grooves (17, 17 ', 17 ", 17'") in which sealing elements (23 and 23 ', 23 ", 23'" illustrated), preferably in the form of O-rings or specific seals. The preferably arcuate piston (4) preferably consists of two grooves (20, 20 ') in which sealing elements (23 "" and 23 ""', not shown) are housed, preferably in the form of O-rings. -rings or specific joints. The ends of the pistons (3,4) are preferably composed of notches (18, 18 ', 19, 19') so as to form a small gap when the pins (3,4) are in contact to facilitate the passage fluid between the pumping chambers (31, 32) and the inlet and outlet ports (5, 5 ', 6, 6').
Selon les figures 1 et 5b, 6a, 7b et 8a les deux pistons (3,4) sont placés à l'intérieur de la cavité de manière à former deux chambres de pompage (3 1 ,32), chacune située de part et d'autre des extrémités des pistons (3,4), en liaison alternativement avec les ports d'entrée (5,5') et les ports de sortie (6,6'). Les éléments d'étanchéité (23,23 ',23",23" \ 23 " ", 23""') assurent l'étanchéité entre les ports d'entrée (5,5') et les ports de sortie (6,6'). According to FIGS. 1 and 5b, 6a, 7b and 8a, the two pistons (3, 4) are placed inside the cavity so as to form two pumping chambers (3 1, 32), each located on both sides of the cavity. other ends of the pistons (3,4), in connection alternately with the input ports (5,5 ') and the output ports (6,6'). The sealing elements (23,23 ', 23 ", 23" \ 23 "", 23 ""') seal between the input ports (5,5 ') and the output ports (6, 6 ').
Selon la figure 5c, les ports de sortie (6,6') sont rel iés à un canal de sortie (7). Selon al figure 3b, les ports d'entrée (5,5') sont en liaison avec un réservoir ou un canal d'entrée commun non représenté. Selon les figures 5a, 6a, 7a et 8a, la rotation de 360° du rotor ( 10) a pour effet de déplacer le piston (3) de manière alternative, ce qui correspond à un cycle de pompage complet. Les phases successives du cycle de pompage se composent de la manière suivante: selon la figure 5a, lorsque le piston (3) est en appui sur le piston (4), la chambre de pompage (3 1 ) est ouverte et en liaison avec le port de sortie (6). La chambre de pompage (32) est fermée et en liaison avec le port d'entrée (5'), le rotor ( 10) est en position 0. Selon la figure 6a, lorsque le rotor ( 10) tourne de 0 à 90°, le piston (3) se déplace dans le sens al ler et appuie sur le piston (4) de manière à le déplacer et à fermer/vider la chambre de pompage (3 1 ) tout en expulsant le fluide vers le port de sortie (6). Le déplacement du piston (3) a également pour effet d'ouvrir et remplir la chambre de pompage (32) qui est en liaison avec le port d'entrée (5'). Selon la figure 7a, lorsque le rotor ( 10) tourne de 90° à 210°, le piston (3) se déplace dans le sens aller et appuie sur le piston (4) de manière à le déplacer et mettre la chambre de pompage (32) en l iaison avec le port de sortie (6'). Selon la figure 8a, lorsque le rotor ( 10) tourne de 210° à 250°, le piston (3) se déplace dans le sens retour et vient fermer/vider la chambre de pompage (32) tout en expulsant le fluide par le port de sortie (6'). Le déplacement du piston (3) a également pour effet d'ouvrir et rempl ir la chambre de pompage (31 ) en liaison avec le port d'entrée (5). Selon la figure 5a, lorsque le rotor ( 10) tourne de 250° à 360°, le piston (3) se déplace dans le sens retour et appuie sur le piston (4) de manière à la déplacer et à positionner la chambre de pompage (3 1 ) à nouveau en l iaison avec le port de sortie (6), complétant ainsi le cycle de pompage. Les corps de pompe supérieur et inférieur (2',2) peuvent être remplacés par des demi-corps de pompe latéraux avant-arrière ou droite-gauche selon l 'orientation de la pompe. Seconde variante According to FIG. 5c, the output ports (6, 6 ') are connected to an output channel (7). According to FIG. 3b, the input ports (5, 5 ') are connected to a reservoir or a common input channel that is not shown. According to FIGS. 5a, 6a, 7a and 8a, the 360 ° rotation of the rotor (10) has the effect of displacing the piston (3) alternately, which corresponds to a complete pumping cycle. The successive phases of the pumping cycle are composed as follows: according to FIG. 5a, when the piston (3) is resting on the piston (4), the pumping chamber (3 1) is open and in connection with the output port (6). The pumping chamber (32) is closed and in connection with the input port (5 '), the rotor (10) is in position 0. According to Figure 6a, when the rotor (10) rotates from 0 to 90 ° , the piston (3) moves in the direction al ler and presses on the piston (4) so as to move it and to close / empty the pumping chamber (3 1) while expelling the fluid towards the output port ( 6). The movement of the piston (3) also has the effect of opening and filling the pumping chamber (32) which is connected to the input port (5 '). According to FIG. 7a, when the rotor (10) rotates from 90 ° to 210 °, the piston (3) moves in the forward direction and presses on the piston (4) so as to move it and put the pumping chamber ( 32) in conjunction with the output port (6 '). According to FIG. 8a, when the rotor (10) rotates from 210 ° to 250 °, the piston (3) moves in the return direction and comes to close / empty the pumping chamber (32) while expelling the fluid through the port output (6 '). The displacement of the piston (3) also has the effect of opening and filling the pumping chamber (31) in connection with the inlet port (5). According to FIG. 5a, when the rotor (10) rotates from 250 ° to 360 °, the piston (3) moves in the return direction and presses on the piston (4) so as to move it and position the pumping chamber (3 1) again in laison with the output port (6), thus completing the pumping cycle. The upper and lower pump casings (2 ', 2) can be replaced by front-rear or right-left side pump casings depending on the orientation of the pump. Second variant
Selon les figures 9, 11, 13, la pompe (101) se compose de deux corps de pompe (102,102') ayant chacun une cavité (122,122') préférablement sous forme de trou circulaire, placés face à face de manière à former deux chambres de pompage (131,132) lorsque les pistons (103,104) sont placés dans les cavités (122,122'). Les pistons (103,103') sont préférablement formés d'un support (160) ayant au moins une partie entourant les corps de pompe (102,102') et permettant de mettre les extrémités du piston (104) en opposition aux pistons (103, 103') de manière à former les deux chambres de pompage (131,132). Les cavités (122,122') sont préférablement opposées coaxiales et linéaires. Les ports d'entrée (105,105') et sortie (106,106') sont placés sur les corps de pompe (102,102') de manière à être en liaison avec les chambres de pompage (131,132). Les ports d'entrée (105,105') et sortie (106,106') peuvent être communiquant respectivement dans les deux corps de pompe (102,102'). Deux éléments de guidage (111,111 '), préférablement sous forme de roulements ou paliers, sont placés sur un axe excentré (112) situé sur un rotor (110) fixé à un actuateur (150), préférablement sous forme d'un moteur. L'élément de guidage (111') est placé dans l'ouverture (140), préférablement sous la forme d'un oblong, située sur le support (160) entre aux pistons (103,103') de manière à déplacer les pistons (103, 103') lors de la rotation du rotor (110). L'élément de guidage (111) est placé dans l'ouverture (116) située entre les deux extrémités du piston (104) de manière à déplacer le piston (104) lors de la rotation du rotor (110). L'ouverture (116) est préférablement sous la forme d'un oblong ayant un profil spécifique, comprenant des rayons (170,170') sur les faces perpendiculaires à l'axe du piston (104) et ayant un espace (116') avec l'élément de guidage (III) calculés de manière à entraîner et commander le piston (104) en retard/décalage avec le mouvement des pistons (103,103') pour réaliser les mêmes séquences de pompage que précédemment décrites dans la première variante de l'invention. Les éléments d'étanchéité ( 123 et autres non numérotés) placés sur les pistons ( 103, 103', 104) sont préférablement sous la forme d'O-rings. According to FIGS. 9, 11, 13, the pump (101) consists of two pump bodies (102, 102 ') each having a cavity (122, 122') preferably in the form of a circular hole, placed facing each other so as to form two chambers pumping (131,132) when the pistons (103,104) are placed in the cavities (122,122 '). The pistons (103, 103 ') are preferably formed of a support (160) having at least a portion surrounding the pump bodies (102, 102') and for placing the ends of the piston (104) in opposition to the pistons (103, 103 ' ) so as to form the two pumping chambers (131, 132). The cavities (122,122 ') are preferably opposite coaxial and linear. The input (105,105 ') and output (106,106') ports are placed on the pump bodies (102,102 ') so as to be connected to the pump chambers (131,132). The input (105,105 ') and output (106,106') ports may be communicating respectively in the two pump bodies (102,102 '). Two guide members (111, 111 '), preferably in the form of bearings or bearings, are placed on an eccentric pin (112) on a rotor (110) attached to an actuator (150), preferably in the form of a motor. The guide member (111 ') is placed in the opening (140), preferably in the form of an oblong, located on the support (160) between the pistons (103, 103') so as to displace the pistons (103). , 103 ') during rotation of the rotor (110). The guide member (111) is placed in the opening (116) between the two ends of the piston (104) so as to move the piston (104) during rotation of the rotor (110). The opening (116) is preferably in the form of an oblong having a specific profile, including spokes (170, 170 ') on the faces perpendicular to the axis of the piston (104) and having a space (116') with (III) calculated to drive and control the piston (104) in delay / offset with the movement of the pistons (103, 103 ') to achieve the same pumping sequences as previously described in the first variant of the invention. The sealing elements (123 and other unnumbered) placed on the pistons (103, 103 ', 104) are preferably in the form of O-rings.
Les déplacements angulaires de l 'élément du rotor ( 10, 1 10), correspondants aux phases de pompage, sont donnés à titre indicatif et peuvent être adaptés en fonction de la géométrie et la taille de la pompe. The angular displacements of the rotor element (10, 1 10), corresponding to the pumping phases, are given as an indication and can be adapted according to the geometry and the size of the pump.
Les éléments de guidage ( 1 1 1 , 1 1 1 ') peuvent être formés par un seul élément de guidage ( 1 1 1 ) placé dans les deux ouvertures ( 1 1 6, 140). The guide elements (1 1 1, 1 1 1 ') can be formed by a single guide element (1 1 1) placed in the two openings (1 1 6, 140).
Troisième variante Selon les figures 14, 1 5, 17 et, 1 8 la pompe (201 ) se compose d'un corps de pompe (202) ayant une cavité (222) préférablement sous forme de trou cylindrique formant une chambre de pompage (231 ) lorsque les pistons (203,204) sont placés dans la cavité (222). Le port d'entrée (205) et le port de sortie (206) sont placés sur le corps de pompe (202) de manière à être en liaison avec la chambre de pompage (231 ). Deux éléments de guidage (21 1 ,21 1 '), préférablement sous forme de roulements ou paliers, sont placés sur un axe excentré (212) situé sur un rotor (210) fixé à un actuateur (250), préférablement sous forme d'un moteur. L'élément de guidage (21 Γ) est placé dans l'ouverture (240), préférablement sous la forme d'oblong, située sur le support (260) à une extrémité du piston (203) de manière à déplacer linéairement le piston (203) selon son axe lors de la rotation du rotor (2 1 0). L'élément de guidage (21 1 ) est placé dans l'ouverture (216) située à une extrémité du piston (204) de manière à déplacer linéairement le piston (204) selon son axe lors de la rotation du rotor (210). Les ouvertures (216, 240) sont préférablement sous la forme d'oblong. L'ouverture (216) est préférablement sous la forme d'un oblong, ayant un profil spécifique, comprenant des rayons (270,270') sur les faces perpendiculaires à l 'axe du piston (204) et ayant un espace (216') avec l'élément de guidage (21 1 ) calculés de manière à entraîner et commander le piston (204) en retard/décalage avec le mouvement du piston (203) pour réaliser les séquences de pompage similaires aux variantes précédemment décrites. Third variant According to FIGS. 14, 15, 17 and 18 the pump (201) consists of a pump body (202) having a cavity (222) preferably in the form of a cylindrical hole forming a pumping chamber (231). ) when the pistons (203,204) are placed in the cavity (222). The input port (205) and the output port (206) are placed on the pump body (202) so as to be connected to the pump chamber (231). Two guide elements (21 1, 21 1 '), preferably in the form of bearings or bearings, are placed on an eccentric axis (212) located on a rotor (210) fixed to an actuator (250), preferably in the form of a motor. The guide element (21 Γ) is placed in the opening (240), preferably in oblong form, on the support (260) at one end of the piston (203) so as to move the piston linearly ( 203) along its axis during rotation of the rotor (2 1 0). The guide member (21 1) is placed in the opening (216) at one end of the piston (204) so as to linearly move the piston (204) along its axis during rotation of the rotor (210). The openings (216, 240) are preferably in the form of oblong. The opening (216) is preferably in the form of a oblong, having a specific profile, comprising spokes (270,270 ') on the faces perpendicular to the axis of the piston (204) and having a space (216') with the guide element (21 1) calculated so as to cause and controlling the piston (204) in delay / offset with the movement of the piston (203) to perform the pumping sequences similar to the previously described variants.
Selon les figures 19a à 22a et 19b à 22b, la rotation de 360° du rotor (210) a pour effet de déplacer les pistons (203, 204) de man ière alternative, ce qui correspond à un cycle de pompage complet. Les phases successives du cycle de pompage se composent de la manière suivante: selon les figures 22a et 22b, lorsque le piston (203) est en appui sur le piston (204), la chambre de pompage (23 1 ) est fermée et en liaison avec le port de sortie (6). Le rotor (210) est en position 0. According to FIGS. 19a to 22a and 19b to 22b, the 360 ° rotation of the rotor (210) has the effect of moving the pistons (203, 204) alternately, which corresponds to a complete pumping cycle. The successive phases of the pumping cycle are composed as follows: according to FIGS. 22a and 22b, when the piston (203) bears on the piston (204), the pumping chamber (23 1) is closed and connected with the output port (6). The rotor (210) is in position 0.
Selon les figures 19a et 19b, lorsque le rotor (2 1 0) tourne de 0 à 120°, le piston (204) se déplace dans le sens aller et appuie sur le piston (203) de manière à le déplacer et à fermer/vider la chambre de pompage (23 1 ). La chambre de pompage (23 1 ) se déplace vers le port d'entrée (205) tout en restant fermée. Selon les figures 20a et 20b, lorsque le rotor (210) tourne de 120° à 210°, le piston (204) se déplace dans le sens retour ce qui a pour effet d'ouvrir la chambre (23 1 ) et d'aspirer le fluide dans la chambre (23 1 ) depuis le port d'entrée (205). Le piston (203) reste en position fixe durant une partie du déplacement du piston (204). According to FIGS. 19a and 19b, when the rotor (2 1 0) rotates from 0 to 120 °, the piston (204) moves in the forward direction and presses on the piston (203) so as to move and close it / empty the pumping chamber (23 1). The pumping chamber (23 1) moves to the input port (205) while remaining closed. According to Figures 20a and 20b, when the rotor (210) rotates from 120 ° to 210 °, the piston (204) moves in the return direction which has the effect of opening the chamber (23 1) and to suck the fluid in the chamber (23 1) from the inlet port (205). The piston (203) remains in a fixed position during a portion of the displacement of the piston (204).
Selon la figure 21 a et 21 b, lorsque le rotor (210) tourne de 210° à 300°, le piston (203) se déplace dans le sens retour en même temps que le piston (204), ce qui a pour effet de déplacer la chambre (231 ) ver^ le port de sortie (206). Selon la Figure 22a et 22b, lorsque le rotor (2 10) tourne de 300° à 360°, le piston (204) se déplace dans le sens aller ce qui a pour effet de fermer/vider la chambre (23 1 ) vers le port de sortie (206). Lorsque le piston (204) est en appui sur le piston (203) le cycle de pompage est terminé. According to Fig. 21a and 21b, as the rotor (210) rotates from 210 ° to 300 °, the piston (203) moves in the return direction together with the piston (204), which has the effect of moving the chamber (231) to the output port (206). According to Figs. 22a and 22b, when the rotor (2 10) rotates 300 ° to 360 °, the piston (204) moves in the forward direction which has the effect of closing / emptying the chamber (23 1) towards the output port (206). When the piston (204) bears on the piston (203), the pumping cycle is completed.
Les éléments d'étanchéité (223 et autres non numérotés) placés sur les pistons (203, 204) sont préférablement sous la forme d'O-rings. The seal members (223 and other unnumbered) on the pistons (203, 204) are preferably in the form of O-rings.
Les éléments de guidage (21 1 ,21 Γ) peuvent être formés par un seul élément de guidage (21 1 ) en placés dans les deux ouvertures (216,240). The guide elements (21 1, 21 Γ) can be formed by a single guide element (21 1) placed in the two openings (216,240).
Quatrième variante Selon les figures 23 à 28 la pompe (301 ) se compose d'un corps de pompe (302) ayant une cavité (322) préférablement sous forme de trou circulaire formant une chambre de pompage (33 1 ) lorsque les pistons (303,304) sont placés dans la cavité (322). Le port d'entrée (305) et le port de sortie (306) sont placés sur le corps de pompe (302) de manière à être en liaison avec la chambre de pompage (33 1 ). Un élément de guidage (3 1 1 ), préférablement sous forme de roulement ou palier, est placé sur un axe excentré (3 1 2) situé sur un rotor (3 10) fixé à un actuateur (350), préférablement sous forme d'un moteur. L'élément de guidage (3 1 1 ) est placé dans l 'ouverture (340), préférablement sous la forme d'oblong, située à sur un support d'entraînement (360) maintenant préférablement le piston (303) par l ' intermédiaire d'un axe ou pin (353) fixé(e) au support d'entraînement (360), de manière à déplacer l inéairement le piston (303) selon son axe lors de la rotation du rotor (3 10). Un second axe ou pin (354) fixé(e) au support d'entraînement (360) est placé(e) dans une ouverture (3 1 6) située à une extrémité du piston (304) de manière à déplacer linéairement le piston (304) selon son axe lors de la rotation du rotor (3 10). L'ouverture (316) est préférablement sous la forme d'un oblong ayant ainsi un espace (316') avec l 'axe ou pin (354) calcu lés de manière à entraîner et commander le piston (304) en retard/décalage avec le mouvement du piston (303) pour réaliser les séquences de pompage similaires aux variantes précédemment décrites. L'actuateur (350), le rotor (3 10) et le support d'entraînement sont préférablement fixé sur un support de pompe (352) de manière à pouvoir recevoir le corps de pompe (302) sous forme d'élément amovible. Fourth variant According to FIGS. 23 to 28 the pump (301) consists of a pump body (302) having a cavity (322) preferably in the form of a circular hole forming a pumping chamber (33 1) when the pistons (303,304 ) are placed in the cavity (322). The input port (305) and the output port (306) are placed on the pump body (302) so as to be connected to the pump chamber (33 1). A guide element (3 1 1), preferably in the form of a bearing or a bearing, is placed on an eccentric axis (3 1 2) located on a rotor (3 10) fixed to an actuator (350), preferably in the form of a a motor. The guide element (3 1 1) is placed in the opening (340), preferably in the form of an oblong, located on a drive support (360), now preferably the piston (303) via a pin or pin (353) fixed (e) to the drive carrier (360), so as to move lamentarily the piston (303) along its axis during the rotation of the rotor (3 10). A second pin or pin (354) attached to the drive carrier (360) is placed in an opening (3 1 6) at one end of the piston (304) to move the piston linearly ( 304) along its axis during the rotation of the rotor (3 10). The opening (316) is preferably in the form of an oblong, thus having a space (316 ') with the axis or pin (354) calculated to drive and control the piston (304) in delay / offset with the movement of the piston (303) to perform the pumping sequences similar to the previously described variants. The actuator (350), the rotor (3 10) and the drive carrier are preferably attached to a pump mount (352) so as to be able to receive the pump body (302) as a removable member.
Les éléments d'étanchéité (323 et autres non numérotés) placés sur les pistons (303, 304) sont préférablement sous la forme d'O-rings. Seals (323 and other unnumbered) placed on the pistons (303, 304) are preferably in the form of O-rings.
Cinquième variante Fifth variant
Selon les figures 29 à 32 la pompe (401 ) se compose d'un corps de pompe (402) ayant une cavité (422) préférablement sous forme de trou cylindrique formant une chambre de pompage (43 1 ) lorsque les pistons (403,404) sont placés dans la cavité (422). Le piston 404 est commandé par un axe de commande (480) co-axial au piston (403). L'étanchéité entre l 'axe de commande (480) et le piston (403) est assuré par un joint d'étanchéité (425), préférentiellement sous le forme d'un O-ring. Le port d'entrée (405) et le port de sortie (406) sont placés sur le corps de pompe (402) de manière à être en liaison alternativement avec la chambre de pompage (431 ) selon la position des pistons (403,404). Un axe excentré (412), préférablement sous forme de came à trois lobes, est placé sur un rotor (410) fixé à un actuateur (450), préférablement sous forme d'un moteur. L'axe excentré (41 2) est placé dans les ouvertures (416,440), préférablement sous la forme d'oblongs ayant un profil spécifique, comprenant des rayons (470,470') sur les faces perpendiculaires à l'axe piston (404) et ayant un espace (416) avec l'axe excentré (412), de manière à déplacer l inéairement respectivement les pistons (404, 403) selon leur axe lors de la rotation du rotor (410). According to FIGS. 29 to 32, the pump (401) consists of a pump body (402) having a cavity (422) preferably in the form of a cylindrical hole forming a pumping chamber (43 1) when the pistons (403, 404) are placed in the cavity (422). The piston 404 is controlled by a control axis (480) coaxial with the piston (403). Sealing between the control shaft (480) and the piston (403) is provided by a seal (425), preferably in the form of an O-ring. The input port (405) and the output port (406) are placed on the pump body (402) so as to be alternately connected to the pumping chamber (431) according to the position of the pistons (403, 404). An eccentric axis (412), preferably in the form of a three-lobed cam, is placed on a rotor (410) attached to an actuator (450), preferably in the form of a motor. The eccentric axis (41 2) is placed in the openings (416,440), preferably in the form of oblongs having a specific profile, including spokes (470,470 ') on the faces perpendicular to the piston axis (404) and having a space (416) with the eccentric axis (412), of in such a way that the pistons (404, 403) are respectively displaced axially during the rotation of the rotor (410).
Le profil de l'axe (4 12) correspond préférablement à une came à trois lobes, et un espace (416) sont calculés de manière à entraîner et commander le piston (404) en retard/décalage avec le mouvement du piston (403) pour réaliser les séquences de pompage similaires aux variantes précédemment décrites. La came à trois lobes et les arrondis (490,490') permettent de déplacer de manière contrôlée et sans jeu le piston (404) indépendamment de la friction due au joint (425) entre l'axe de commande (480) et le piston (404). The axis profile (4 12) preferably corresponds to a three-lobe cam, and a space (416) is calculated to drive and control the piston (404) late / offset with the movement of the piston (403). to perform the pumping sequences similar to the previously described variants. The three-lobe cam and the rounded (490,490 ') allow the piston (404) to be moved in a controlled and play-free manner independently of the friction due to the seal (425) between the control shaft (480) and the piston (404). ).
Le piston (403) est préférablement creux de manière recevoir l'axe de commande (480) du piston (404) et former une partie de la chambre de pompage (43 1 ) par la différence des diamètres des pistons (403,404), réduisant ainsi la tai l le du système. The piston (403) is preferably hollow so as to receive the control shaft (480) of the piston (404) and form a part of the pumping chamber (43 1) by the difference of the diameters of the pistons (403, 404), thereby reducing the tai l of the system.
Les éléments d'étanchéité (423 et autres non numérotés) placés sur les pistons (403, 404) sont préférablement sous la forme d'O-rings. Seals (423 and other unnumbered) on the pistons (403, 404) are preferably in the form of O-rings.
Dans une autre variante (non illustrée) les cavités ( 122, 122') peuvent être parallèles excentrées de manière à réduire l 'encombrement de la pompe. In another variant (not shown) the cavities (122, 122 ') may be eccentric parallel so as to reduce the size of the pump.
Dans une autre variante (non i l lustrée) la cavité (22) peut être réalisée sous la forme d'un tore creux placé sur l'un des corps de pompe (2,2'). In another variant (not lustrous) the cavity (22) can be made in the form of a hollow torus placed on one of the pump bodies (2, 2 ').
L'actuateur peut être sous la forme de n' importe quel système électromécanique convertissant une énergie électrique en un mouvement mécanique actionnant le rotor. L'actuateur peut être adapté de manière à actionner le rotor selon un mouvement séquentiel non continu comme par exemple un électro-aimant. Le mouvement du rotor peut alors être piloté de manière à réaliser tout ou partie de la séquence de pompage lors de l'actionnement de l'actuateur de manière à dél ivrer des doses prédéfinies de fluide communément appelé « bolus ». The actuator may be in the form of any electromechanical system converting electrical energy into a mechanical movement operating the rotor. The actuator may be adapted to actuate the rotor in a non-continuous sequential motion such as an electromagnet. The rotor movement can then be controlled from so as to realize all or part of the pumping sequence during actuation of the actuator so as to deluge predefined doses of fluid commonly called "bolus".
Dans une variante (non illustrée), le réservoir de la pompe peut être intégré à l 'un des corps de pompe de manière à réduire l'encombrement de la pompe et le récipient contenant le fluide à pomper. Le réservoir peut être, par exemples, sous la forme d'un cylindre avec un bouchon/piston amovible ou d'une poche souple. Le réservoir peut être pré-rempli de manière à former avec le corps de pompe un ensemble amovible destiné à un usage unique sous forme de cartouche venant se loger sur un élément durable comprenant tout ou partie de l 'élément de guidage, tout ou partie du rotor et tout ou partie de l'actuateur. Dans une autre variante,; non il lustrée, l 'actuateur peut être réal isé sous la forme d'un actuateur mécanique sans moteur tel qu'un mouvement à ressort ou un entraînement à actionnement manuel comme un bouton poussoir, un cliquet, une gâchette ou tout autre mécanisme entraînant le rotor ou l'élément de guidage. Ce type d'entraînement sans moteur permet de réaliser par exemple une pompe-patch col lée sur le corps ou une pompe portable à usage unique pour la diffusion de médicament en continu ou en dosage manuel sans élément électronique, ni batterie. Cette variante peut également se composer d 'un réservoir intégré, lui-même pouvant être prérempli. In a variant (not shown), the reservoir of the pump can be integrated with one of the pump bodies so as to reduce the size of the pump and the container containing the fluid to be pumped. The reservoir may be, for example, in the form of a cylinder with a removable cap / piston or a flexible pouch. The tank may be pre-filled so as to form with the pump body a removable assembly for a single use in the form of cartridge housed on a durable element comprising all or part of the guide element, all or part of the rotor and all or part of the actuator. In another variant; If it is not lustrous, the actuator can be made in the form of a mechanical actuator without a motor such as a spring-loaded movement or a manually actuated drive such as a pushbutton, a pawl, a trigger or any other mechanism driving the actuator. rotor or guide element. This type of drive without motor makes it possible, for example, to produce a patch pump mounted on the body or a portable disposable pump for continuously dispensing medication or manual dosing without an electronic element or battery. This variant can also consist of an integrated reservoir, which itself can be pre-filled.
L'étanchéité entre les parties mobiles est préférablement réalisée grâce à un élastomère, un joint surmoulé ou tout autre élément d'étanchéité. Toutefois, il est possible de réaliser la pompe sans joint d'étanchéité par ajustement par exemple. Ce type d'ajustement peut être réalisé en pièces céramiques ou métall iques communément uti lisées dans les pompes sans joints. Les éléments constituant la pompe sont préférablement en plastique et jetables. La pompe peut être stérilisée pour la distribution d'aliment ou de médicament par exemple. Le choix des matériaux n'est cependant pas limité aux plastiques. The sealing between the moving parts is preferably achieved by an elastomer, an overmolded seal or any other sealing element. However, it is possible to realize the pump without seal by adjustment for example. This type of adjustment can be made of ceramic or metal parts commonly used in seamless pumps. The elements constituting the pump are preferably plastic and disposable. The pump can be sterilized for dispensing food or medicine for example. The choice of materials, however, is not limited to plastics.
Il est possible de contrôler et/ou actionner l 'actuateur de la pompe par n' importe quel moyen électronique embarqué et/ou piloté par une télécommande sans fi l. It is possible to control and / or actuate the pump actuator by any electronic means on board and / or controlled by a wireless remote control.
Il est possible d'ajouter des capteurs ou éléments de capteurs sur l 'un ou pl usieurs composants de la pompe afin de mesurer et/ou contrôler différents paramètres liés à son utilisation tels que par exemples: la température, la pression du fluide pompé, l 'humidité ambiante, les vibrations, les déplacements ou la position des pièces mobi les. It is possible to add sensors or sensor elements to one or several components of the pump in order to measure and / or control various parameters related to its use, such as for example: the temperature, the pressure of the pumped fluid, ambient humidity, vibration, movement or position of moving parts.
Bien que l'invention soit décrite selon plusieurs modes de réalisation, il existe d'autres variantes et/ou combinaisons de variantes qui ne sont pas présentées. La portée de l ' invention n'est donc pas limitée aux modes de réalisation et variantes décrits précédemment. Although the invention is described according to several embodiments, there are other variants and / or combinations of variants that are not presented. The scope of the invention is therefore not limited to the embodiments and variants described above.

Claims

Revendications claims
1 . Une pompe comprenant, au moins deux pistons placés dans au moins une cavité située dans au moins un corps de pompe, formant au moins une chambre de pompage, située entre les pistons et venant alternativement en l iaison avec au moins un port d'entrée et au moins un port de sortie situés sur le corps de pompe caractérisée par au moins un axe excentrique fixé sur un rotor, déplaçant au moins un piston de manière à successivement remplir au moins une chambre de pompage lorsque cel le-ci est en liaison avec au moins un port d'entrée, puis de déplacer la chambre remplie de fluide, entre les ports d'entrée et sortie, et vider la chambre lorsque celle-ci est en liaison avec au moins un port de sortie. 1. A pump comprising at least two pistons placed in at least one cavity in at least one pump body, forming at least one pumping chamber, located between the pistons and alternately in engagement with at least one inlet port and at least one output port located on the pump body characterized by at least one eccentric pin fixed to a rotor, displacing at least one piston so as to successively fill at least one pumping chamber when this is connected with the least one input port, then move the fluid-filled chamber between the input and output ports, and empty the chamber when connected to at least one output port.
2. Pompe selon la revendication 1 , dont le rotor est entraîné par un actuateur. 2. Pump according to claim 1, whose rotor is driven by an actuator.
3. Pompe selon la revendication I , dont l 'axe excentrique est placé dans au moins une ouverture ayant un espace calculé de manière à déplacer les pistons en retard/décalage l'un vis-à-vis de l'autre lors du mouvement de l 'axe excentrique. 3. Pump according to claim 1, wherein the eccentric axis is placed in at least one opening having a space calculated so as to move the pistons lagging / shifting with respect to each other during the movement of the eccentric axis.
4. Pompe selon la revendication 2, dont l'ouverture est préférablement sous forme d'oblong. 4. Pump according to claim 2, whose opening is preferably in the form of oblong.
5. Pompe selon l'une des revendications I à 4 dont un élément de guidage est placé sur l'axe excentrique du rotor. 5. Pump according to one of claims I to 4, a guide member is placed on the eccentric axis of the rotor.
6. Pompe selon l'une des revendications I à 4 dont le profi l de l'axe excentrique a la forme d'une came à trois lobes. 6. Pump according to one of claims I to 4, the profi l of the eccentric axis has the shape of a cam with three lobes.
7. Pompe selon la revendication 5, dont l'élément de guidage est préférablement sous forme de roulement ou palier. 7. Pump according to claim 5, the guide element is preferably in the form of bearing or bearing.
8. Pompe selon la revend ication 4, dont l 'ouverture en forme d'oblong a un profil spécifique comprenant deux rayons sur les faces perpendiculaire à l'axe d'un piston. 8. Pump according to claim 4, whose oblong-shaped opening has a specific profile comprising two radii on the faces perpendicular to the axis of a piston.
9. Pompe selon la revendication 1 , dont la cavité est de forme torique. 9. Pump according to claim 1, whose cavity is of toric shape.
10. Pompe selon la revendication 1 , dont les pistons sont arqués. 10. Pump according to claim 1, the pistons are arcuate.
1 1 . Pompe selon la revendication I , dont au moins une partie du piston et placé sur un support ayant une ouverture recevant l'axe excentrique. 1 1. Pump according to claim I, of which at least a portion of the piston is placed on a support having an opening receiving the eccentric axis.
12. Pompe selon la revendication I , dont la cavité est formée par deux demi-corps de pompe. 12. Pump according to claim I, the cavity is formed by two pump half-bodies.
13. Pompe selon la revendication 12, dont l'un des demi-corps de pompe comprend au moins un port d'entrée. 13. Pump according to claim 12, wherein one of the pump half-bodies comprises at least one input port.
14. Pompe selon la revendication 12, dont l 'un des demi-corps de pompe comprend au moins un port de sortie. 14. Pump according to claim 12, wherein one of the pump half-bodies comprises at least one output port.
15. Pompe selon la revendication 1 1 , dont les cavités sont parallèles. 15. Pump according to claim 1 1, whose cavities are parallel.
16. Pompe selon l'une des revendications précédentes, destinée à usage médical. 16. Pump according to one of the preceding claims, intended for medical use.
17. Pompe selon l'une des revendications précédentes, dont l'étanchéité entre les parties mobiles est réalisée avec au moins un élastomère. 17. Pump according to one of the preceding claims, wherein the seal between the moving parts is made with at least one elastomer.
18. Pompe selon l'une des revendications précédentes, dont les pièces sont en plastique et jetables. 18. Pump according to one of the preceding claims, whose parts are plastic and disposable.
19. Pompe selon l'une des revendications précédentes, destinée à être implantée dans le corps. 19. Pump according to one of the preceding claims, intended to be implanted in the body.
20. Pompe selon l'une des revendications précédentes, ayant un réservoir intégré à l'un des corps de pompe. 20. Pump according to one of the preceding claims, having a reservoir integrated in one of the pump body.
21 . Pompe selon l'une des revendications précédentes, dont le corps de pompe est amovible. 21. Pump according to one of the preceding claims, wherein the pump body is removable.
22. Pompe selon l'une des revendications précédentes, dont l'actuateur est de type électromécanique. 22. Pump according to one of the preceding claims, whose actuator is electromechanical type.
23. Pompe selon l'une des revendications I à 2 1 , dont l 'actuateur est réal isé sous la forme d'un entraînement mécan ique sans moteur. 23. Pump according to one of claims I to 2 1, whose actuator is realisé in the form of a mechanical drive without motor.
PCT/IB2014/001149 2013-06-25 2014-06-23 Positive-displacement micropump WO2014207532A1 (en)

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Publication number Priority date Publication date Assignee Title
EP2992916A1 (en) * 2014-04-18 2016-03-09 Becton Dickinson and Company Split piston metering pump
EP3050585A1 (en) * 2015-01-27 2016-08-03 Weibel CDS AG Dosing device for dispensing a fluid under aseptic conditions
US10881800B2 (en) 2016-06-08 2021-01-05 Shl Medical Ag Device for dispensing a fluid
WO2022159989A1 (en) * 2021-01-25 2022-07-28 Avails Medical, Inc. Apparatus, systems, and methods for preparing an output sample with aeration

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Publication number Priority date Publication date Assignee Title
GB157692A (en) 1920-07-06 1921-01-27 Montague William Tutt Improvements in force-pumps
US1516032A (en) 1923-08-02 1924-11-18 Charles E White Pump
US2833226A (en) * 1954-01-05 1958-05-06 Meux Albin De Laage De Pumps and compressors
BE889258A (en) * 1981-06-17 1981-12-17 Vercruysse Edgar L M MACHINE CONSISTING OF A CYLINDER, SUPPLY TUBE (S) AND DRAIN PIPE FOR TRANSFERRING MATERIAL FROM ONE MEDIUM TO ANOTHER MEDIUM
US5639220A (en) 1994-09-09 1997-06-17 Brother Kogyo Kabushiki Kaisha Pump with inlet and outlet simultaneously exposed to pump chamber and method of operating same

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2992916A1 (en) * 2014-04-18 2016-03-09 Becton Dickinson and Company Split piston metering pump
US10004845B2 (en) 2014-04-18 2018-06-26 Becton, Dickinson And Company Split piston metering pump
US10512719B2 (en) 2014-04-18 2019-12-24 Becton, Dickinson And Company Split piston metering pump
EP3597234A1 (en) * 2014-04-18 2020-01-22 Becton, Dickinson and Company Split piston metering pump
EP3804785A1 (en) * 2014-04-18 2021-04-14 Becton, Dickinson and Company Split piston metering pump
US11793929B2 (en) 2014-04-18 2023-10-24 Becton, Dickinson And Company Split piston metering pump
EP3050585A1 (en) * 2015-01-27 2016-08-03 Weibel CDS AG Dosing device for dispensing a fluid under aseptic conditions
US10653846B2 (en) 2015-01-27 2020-05-19 Idorsia Pharmaceuticals Ltd Dosing apparatus for dispensing a fluid under aseptic conditions
US11040146B2 (en) 2015-01-27 2021-06-22 Shl Medical Ag Dosing apparatus for dispensing a fluid under aseptic conditions
US10881800B2 (en) 2016-06-08 2021-01-05 Shl Medical Ag Device for dispensing a fluid
WO2022159989A1 (en) * 2021-01-25 2022-07-28 Avails Medical, Inc. Apparatus, systems, and methods for preparing an output sample with aeration

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