WO2014175018A1 - 自動分析装置 - Google Patents
自動分析装置 Download PDFInfo
- Publication number
- WO2014175018A1 WO2014175018A1 PCT/JP2014/059688 JP2014059688W WO2014175018A1 WO 2014175018 A1 WO2014175018 A1 WO 2014175018A1 JP 2014059688 W JP2014059688 W JP 2014059688W WO 2014175018 A1 WO2014175018 A1 WO 2014175018A1
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- WO
- WIPO (PCT)
- Prior art keywords
- detergent
- storage tank
- automatic analyzer
- detergent storage
- cleaning
- Prior art date
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1004—Cleaning sample transfer devices
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B3/00—Cleaning by methods involving the use or presence of liquid or steam
- B08B3/04—Cleaning involving contact with liquid
- B08B3/08—Cleaning involving contact with liquid the liquid having chemical or dissolving effect
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/15—Preventing contamination of the components of the optical system or obstruction of the light path
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/025—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a carousel or turntable for reaction cells or cuvettes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/04—Details of the conveyor system
- G01N2035/0439—Rotary sample carriers, i.e. carousels
- G01N2035/0441—Rotary sample carriers, i.e. carousels for samples
Definitions
- the present invention relates to an automatic analyzer that performs a qualitative / quantitative analysis of a specimen sample such as blood or urine, and more particularly to an automatic analyzer that includes a detergent storage tank for cleaning a dispensing probe.
- An automatic analyzer for clinical tests is a device that measures specific components in biological samples such as blood and urine.
- the general operation is as follows.
- the automatic analyzer dispenses the sample and reagent into the reaction vessel with a dedicated dispensing probe, and after stirring and reacting, calculates the concentration of the target item from information such as absorbance and luminescence obtained from the reaction solution. I do.
- the inner and outer walls of the dispensing probe are washed with purified water before dispensing the next sample.
- the sample cannot be washed completely with purified water due to the liquidity of the sample and the components (proteins, lipids, etc.), and the previous sample may affect the measurement result of the next sample.
- the dispensing probe is additionally washed with detergent.
- the general operation is as follows. In the automatic analyzer, the detergent is sucked from the external detergent bottle with the dispensing probe, and after the detergent is discharged in the washing tank, the inner wall and the outer wall of the dispensing probe are washed with purified water.
- the detergent used for washing the dispensing probe is an alkaline detergent.
- the water in the detergent evaporates. Thereby, a crystal
- An object of the present invention is to provide an automatic analyzer that can reduce the labor of cleaning a detergent storage tank and suppress a decrease in the amount of analysis processing due to cleaning of the detergent storage tank.
- the present invention provides a sample dispensing mechanism for dispensing a sample using a probe, a cleaning liquid supply port, a detergent supply port, and a waste liquid port, and a detergent for cleaning the probe.
- a pump, a second pump installed on a flow path connecting the detergent tank and the detergent supply port, a solenoid valve installed on a flow path connecting the waste liquid port and the waste liquid tank, and the detergent When the predetermined condition for cleaning the storage tank is not satisfied, and the remaining amount of the detergent stored in the detergent storage tank is equal to or less than the predetermined amount, the second pump is driven, and the remaining amount of the detergent The first to make a predetermined amount When the predetermined condition for cleaning the detergent storage tank is satisfied, the electromagnetic valve is opened to drain the detergent in the detergent
- FIG. 1 It is a block diagram of the automatic analyzer which is the 1st Embodiment of this invention. It is a block diagram of the detergent storage tank system used for the automatic analyzer which is the 1st Embodiment of this invention. It is a perspective view of the detergent storage tank unit shown by FIG. It is a figure which shows an example of a structure of the operation screen displayed on the display part of the automatic analyzer which is the 1st Embodiment of this invention. It is a flowchart which shows operation
- FIG. 1 It is a block diagram of the detergent storage tank system used for the automatic analyzer which is the 2nd modification of this invention. It is a block diagram (sectional drawing) of the detergent storage tank used for the automatic analyzer which is the 2nd Embodiment of this invention. It is a top view of the detergent storage tank unit used for the automatic analyzer which is the 3rd Embodiment of this invention. It is a block diagram (perspective view) of the detergent storage tank unit used for the automatic analyzer which is the 4th Embodiment of this invention. It is a top view of the detergent storage tank unit shown by FIG.
- FIG. 1 is a configuration diagram of an automatic analyzer 1000 according to the first embodiment of the present invention.
- the automatic analyzer 1000 includes a reaction tank 1, a reaction vessel 2, a washing mechanism 3 for the reaction vessel 2, a photometer 4, a stirring mechanism 5 (5 1 to 5 2 ), and a washing tank for washing the stirring rod of the stirring mechanism 5.
- 6 (6 1 to 6 2 ), reagent dispensing mechanism 7 (7 1 to 7 2 ), washing tank 8 (8 1 to 8 2 ) for washing the dispensing probe of reagent dispensing mechanism 7, reagent disk 9 ,
- a reagent bottle 10 containing various reagents, a sample dispensing mechanism 11 (11 1 to 11 2 ), a washing tank 12 (12 1 to 12 2 ) for washing the dispensing probe of the sample dispensing mechanism 11, a sample
- a detergent storage tank unit 13 13 1 to 13 2 ) for storing detergent for the dispensing mechanism 11, a sample container 14, a rack 15 for transporting the sample container 14, and a sample transport mechanism 16 are provided.
- the reaction vessel 2 is arranged concentrically on the reaction disk 1.
- the reagent bottle 10 is arranged concentrically on the reagent disk 9.
- a reagent pump 17 is connected to the reagent dispensing mechanism 7.
- a sample pump 18 is connected to the sample dispensing mechanism 11.
- a cleaning pump 19 is connected to the cleaning mechanism 3.
- the mechanism control unit 20 includes a processor, a memory, and the like, and controls the operation of each mechanism. Further, the operator can instruct the mechanism control unit 20 to operate through the operation screen 21 a displayed on the display unit 21.
- the operation instruction is input using an input device such as a keyboard, a mouse, or a touch panel.
- the analysis by the automatic analyzer is performed in the following order.
- the sample dispensing mechanism 11 (11 1 to 11 2 ) dispenses the sample to be analyzed from the sample container 14 to the reaction container 2.
- the reagent dispensing mechanism 7 (7 1 to 7 2 ) dispenses the reagent used for the analysis from the reagent bottle 10 to the reaction container 2.
- the stirring mechanism 5 (5 1 to 5 2 ) stirs the reaction solution.
- the photometer 4 measures the reaction solution every time the reaction vessel 2 passes in front of the photometer 4.
- the mechanism control unit 20 calculates the concentration of the analysis target item based on the photometric data.
- the display unit 21 (information device) displays the result obtained by the density calculation.
- the stirring rod of the stirring mechanism 5 (5 1 to 5 2 ) is cleaned in the cleaning tank 6 (6 1 to 6 2 ) each time stirring is performed.
- the dispensing probe of the reagent dispensing mechanism 7 (7 1 to 7 2 ) is washed in the washing tank 8 (8 1 to 8 2 ) every time it is dispensed.
- the dispensing probe of the sample dispensing mechanism 11 (11 1 to 11 2 ) is cleaned in the cleaning tank 12 (12 1 to 12 2 ) every time it is dispensed. In the cleaning tanks 6, 8 and 12, cleaning is performed using purified water.
- reaction vessel 2 after photometry is washed by the washing mechanism 3 and repeatedly used for the next analysis.
- the details of the detergent storage tank system including the detergent storage tank unit 13 will be described later with reference to FIG.
- FIG. 2 is a configuration diagram of a detergent storage tank system 100A used in the automatic analyzer 1000 according to the first embodiment of the present invention.
- the detergent storage tank system 100A mainly includes a detergent storage tank unit 13, a cleaning liquid supply unit 108, a detergent supply unit 109, a waste liquid unit 110, and a control unit 111.
- the detergent storage tank unit 13 includes a detergent storage tank 101, a cleaning liquid supply port 102, a detergent supply port 103, a drainage port 104, a solenoid valve 105, liquid level sensors 106 (106 1 to 106 2 ), and a waste liquid tank 107.
- the dispensing probe of the sample dispensing mechanism 11 sucks the detergent stored in the detergent storage tank 101 and discharges the sucked detergent to the waste liquid tank 107 or the cleaning tank 12. Thereafter, the inner wall and the outer wall of the dispensing probe are washed with purified water in the washing tank 12.
- the liquid surface of the detergent has reached to the top of the liquid level sensor 106 1, each time the dispensing probe sample dispensing mechanism 11 sucks the detergent from the detergent container 101, accumulated in the detergent container 101 The amount of detergent removed is reduced.
- the mechanism control unit 20 controls the opening and closing of the electromagnetic valve 105.
- the electromagnetic valve 105 When the electromagnetic valve 105 is opened, the detergent and cleaning liquid in the detergent storage tank 101 are discharged. On the other hand, when the electromagnetic valve 105 is closed and the detergent is supplied, the detergent is stored in the detergent storage tank 101.
- the liquid level sensor 106 detects the liquid level in the detergent storage tank 101.
- a cleaning liquid for example, pure water or ion-exchanged water
- a detergent used for cleaning the dispensing probe is supplied from the detergent supply port 103.
- the cleaning liquid supply port 102 is installed above the detergent supply port 103. By supplying the cleaning liquid from the cleaning liquid supply port 102, the detergent crystals adhering to the detergent supply port 103 can be washed away.
- the detergent storage tank unit 13 is connected to a cleaning liquid supply unit 108, a detergent supply unit 109, a drainage unit 110, and a control unit 111.
- the cleaning liquid supply unit 108 includes a cleaning liquid tank 112, a flow path 113 that connects the cleaning liquid tank 112 and the detergent storage tank 101, a pump 114 that sends the cleaning liquid from the cleaning liquid tank 112 to the detergent storage tank 101, and a cleaning liquid supply port 102.
- the detergent supply unit 109 includes a detergent tank 115, a flow path 116 that connects the detergent tank 115 and the detergent storage tank 101, a pump 117 that sends detergent from the detergent tank 115 to the detergent storage tank 101, and a detergent supply port 103.
- the drainage unit 110 includes a drainage port 104, a solenoid valve 105, a flow path 118 that connects the drainage port 104 and the drainage tank 119, and a drainage tank 119.
- the control unit 111 includes a mechanism control unit 20 and a display unit 21.
- the operator can input to the mechanism control unit 20 cleaning parameters that specify conditions for performing cleaning through the operation screen 21 a displayed on the display unit 21.
- the mechanism control unit 227 controls the operation of each mechanism in the vicinity according to the input cleaning parameters.
- the waste liquid tank 107 is used when discharging the detergent sucked by the dispensing probe of the sample dispensing mechanism 11 and also when discharging the overflowed liquid from the detergent storage tank port 120.
- the configuration of the detergent storage tank port 120 will be described later with reference to FIG.
- the waste liquid tank 107 is adjacent to the detergent storage tank 101 and is surrounded by an outer frame 121.
- a drainage port 122 is disposed in the outer frame 121. The liquid discharged from the drain port 122 is discarded to the drain tank 119 through the flow path 123.
- FIG. 3 is a perspective view of the detergent storage tank unit 13 shown in FIG. In FIG. 3, only main parts are displayed to make the drawing easy to see.
- the upper end surface of the partition wall 13 ⁇ / b> W between the detergent storage tank 101 and the waste liquid tank 107 is lower than the upper end surface of the outer frame 121. Thereby, the detergent storage tank port 120 is formed.
- FIG. 4 is a diagram illustrating an example of the configuration of the operation screen 21a displayed on the display unit 21 of the automatic analyzer 1000 according to the first embodiment of the present invention.
- the operation screen 21a is a screen for registering conditions under which the detergent storage tank 101 is cleaned.
- the operator registers the cleaning parameters (such as the cleaning timing of the detergent storage tank 101 and the number of cleanings) in the apparatus via the operation screen 21a.
- the operation screen 21a sets a check box 211 (211a to 211e) for setting a cleaning timing (cleaning start trigger), a text box 212 for setting a cleaning interval, and the number of times the detergent storage tank 101 is cleaned when the cleaning timing comes.
- a text box 213 to be set a setting button 214 for registering the set condition (cleaning parameter), and a cancel button 215 for canceling the set condition and not displaying the operation screen 21a.
- check boxes 211a to 211e for setting the cleaning timing will be specifically described.
- the detergent storage tank 101 is washed when the automatic analyzer 1000 is activated (for example, when the power switch is turned on).
- the detergent storage tank 101 is washed when the automatic analyzer 1000 is terminated (for example, when a predetermined shutdown button is pressed).
- the dispensing probe of the sample dispensing mechanism 11 is washed every time “X” time elapses. At this time, the cleaning is performed “Y” times. Details of the cleaning operation will be described later with reference to FIG.
- FIG. 5 is a flowchart showing the operation of the automatic analyzer 1000 according to the first embodiment of the present invention.
- cleaning parameters are set as shown in FIG.
- steps 1 to 6 preparations for cleaning the detergent storage tank 101 are performed. Specifically, the mechanism control unit 20 determines whether or not the “X” time as the set time has elapsed (step 1).
- the mechanism control unit 20 determines whether the sample dispensing operation is performed by the sample dispensing mechanism 11 or not. Determine whether. (Step 2).
- the mechanism control unit 20 determines whether or not the sample dispensing probe is cleaned with a detergent after the current sample dispensing is completed (step 3). Specifically, when the sample currently being dispensed is a predetermined sample (for example, whole blood), the mechanism control unit 20 determines that the sample dispensing probe is washed with a detergent.
- a predetermined sample for example, whole blood
- step 3 determines that cleaning is performed (step 3; YES), that is, when the detergent in the detergent storage tank 101 is used
- the mechanism control unit 20 waits until the current sample dispensing is completed (step 4).
- the mechanism control unit 20 cleans the sample dispensing probe with the detergent in the detergent storage tank 101 (step 5).
- the mechanism control unit 20 temporarily stops a new sample dispensing after the sample dispensing probe is cleaned (step 6). At this time, other mechanisms such as the reagent dispensing mechanism 7 and the photometer 4 are kept operating. As a result, reagent dispensing and photometry are continued.
- step 6 If the sample is not dispensed at Step 2 (step 2; NO), or if the sample dispensing probe is not washed with a detergent after completion of the current sample dispensing at step 3 (step 3; NO), the process is directly Proceed to step 6.
- the mechanism control unit 20 determines whether or not the detergent amount in the detergent storage tank 101 is equal to or less than the set amount (step 7). Specifically, the mechanism control unit 20, the detergent quantity by the liquid level sensor 106 2 installed at the bottom of the detergent container 101 is equal to or less than a set amount.
- the mechanism controller 20 automatically supplies the detergent (step 8). Specifically, the mechanism control unit 20 drives a pump 117 that sends detergent from the detergent tank 115 to the detergent storage tank 101.
- Steps 9 to 15 the detergent storage tank 101 is cleaned and the detergent is replenished.
- the mechanism control unit 20 opens the electromagnetic valve 105 and discards the detergent in the detergent storage tank 101 (step 9).
- the mechanism control unit 20 closes the electromagnetic valve 105 and supplies the cleaning liquid from the cleaning liquid supply port 102 (step 10).
- the mechanism control unit 20 that drives the pump 114 that sends the cleaning liquid from the cleaning liquid tank 112 to the detergent storage tank 101 causes the supplied cleaning liquid to overflow from the detergent storage tank port 120 to clean the inner wall of the detergent storage tank 101. (Step 11).
- the mechanism control unit 20 drives the pump 117 that sends the detergent from the detergent tank 115 to the detergent storage tank 101 for a predetermined time in the detergent storage tank 101.
- This predetermined time is, for example, longer than the time until the pump 114 is driven and the detergent in the detergent storage tank 101 becomes empty to full (maximum capacity).
- the mechanism controller 20 stops supplying the cleaning liquid after a predetermined time (step 12), opens the electromagnetic valve 105, and discards the cleaning liquid in the detergent storage tank 101 (step 13).
- the mechanism control unit 20 determines whether or not the number of times of cleaning has reached “Y”, which is the number of times set on the operation screen 21a (step 14). If the number of cleanings does not reach the set number of times (step 14; NO), the mechanism control unit 20 performs steps 10 to 13. If the number of washings reaches a set number of times (step 14; YES), the mechanism control unit 20 supplies the detergent to the liquid surface sensor 106 1 detects the liquid surface of the detergent (step 15).
- step 16 the sample dispensing temporarily stopped at step 6 is resumed (step 16), and the process is terminated.
- the detergent storage tank 101 can be automatically cleaned. Therefore, it is possible to reduce the labor of cleaning the detergent storage tank 101. Further, according to the present embodiment, reagent dispensing and photometry are continued while the detergent storage tank 101 is washed. Therefore, it is possible to suppress a decrease in the analysis processing amount by cleaning the detergent storage tank.
- FIG. 6 is a configuration diagram of a detergent storage tank system 100B used in the automatic analyzer 1000 according to the first modification of the present invention.
- FIG. 6 the same parts as those in FIG.
- the mechanism control unit 20 uses the liquid level detection sensor mounted on the sample dispensing probe to measure the liquid level of the detergent in the detergent storage tank 101 and determine the remaining amount of the detergent. .
- the mechanism control unit 20 may calculate the detergent consumption from the number of times the sample dispensing probe is washed, and may calculate and determine the remaining amount from the amount of detergent when full and the calculated detergent consumption.
- the manufacturing cost of the automatic analyzer can be reduced.
- FIG. 7 is a configuration diagram of a detergent storage tank system 100C used in the automatic analyzer 1000 according to the second modification of the present invention.
- FIG. 7 the same parts as those in FIG.
- the position of the detergent supply port 103 is different from that in FIG. 6.
- the detergent supply port 103 is arranged at the lower end (near the bottom) of the detergent storage tank 101.
- FIG. 8 is a configuration diagram (cross-sectional view) of the detergent storage tank unit 13 used in the automatic analyzer 1000 according to the second embodiment of the present invention.
- FIG. 8 the same parts as those in FIG.
- FIG. 8 differs from FIG. 6 in that the detergent storage tank unit 13 includes a spiral groove 101a on the inner peripheral surface of the detergent storage tank 101.
- the cleaning liquid when the detergent storage tank 101 has a large diameter, the cleaning liquid does not reach the entire inner wall of the detergent storage tank 101 and cannot perform uniform cleaning. there is a possibility.
- the cleaning liquid flows along the groove to the entire inner wall of the detergent storage tank 101, the inner wall of the detergent storage tank 101 can be cleaned uniformly.
- FIG. 9 is a top view of the detergent storage tank unit 13 used in the automatic analyzer 1000 according to the third embodiment of the present invention.
- the same parts as those in FIG. FIG. 9 corresponds to the top view of FIG.
- the detergent storage tank unit 13 includes two cleaning liquid supply ports 102a and 102b.
- the two cleaning liquid supply ports 102a and 102b are arranged to be shifted left and right from a center line 101C orthogonal to the axis of the detergent storage tank 101 (axis parallel to the z axis).
- the cleaning liquid supply ports 102a and 102b are arranged at positions to be pointed with respect to the center of the circular cross section (cross section perpendicular to the z axis) of the detergent storage tank 101.
- the cleaning liquid is discharged from the cleaning liquid supply port 102b at the timing when the cleaning liquid discharged from the cleaning liquid supply port 102a reaches the position 102b along the inner wall of the detergent storage tank.
- the timing at which the cleaning liquid is discharged from the cleaning supply ports 102a and 102b is not limited to this, and the cleaning liquid may be discharged simultaneously from the cleaning supply ports 102a and 102b.
- the inner wall can be efficiently cleaned even if the detergent storage tank 101 has a large diameter. This operation is controlled by the control unit 111.
- FIG. 10 is a configuration diagram (perspective view) of the detergent storage tank unit 13 used in the automatic analyzer 1000 according to the fourth embodiment of the present invention.
- FIG. 10 the same parts as those in FIG. Further, in FIG. 10, only main parts are displayed for easy viewing of the drawing.
- the concave (slit-shaped) detergent storage tank port 120 is installed at the upper end of the partition wall 13 ⁇ / b> W so that the cleaning liquid overflows from the detergent storage tank 101 to the outer frame 121.
- the concave (slit-shaped) detergent storage tank port 120 is installed at the upper end of the partition wall 13 ⁇ / b> W so that the cleaning liquid overflows from the detergent storage tank 101 to the outer frame 121.
- the present invention is not limited to this.
- the detergent storage tank unit 13 shown in FIGS. 3 and 9 may be provided with a concave (slit-shaped) detergent storage tank port 120.
- FIG. 11 is a top view of the detergent storage tank unit 13 shown in FIG.
- the supplied cleaning liquid swirls in the detergent storage tank 101 as in the third embodiment, so that the inner wall can be efficiently cleaned even if the detergent storage tank 101 has a large diameter. .
- the present invention is not limited to the above-described embodiments, and includes various modifications.
- the above-described embodiments have been described in detail for easy understanding of the present invention, and are not necessarily limited to those having all the configurations described.
- a part of the configuration of one embodiment can be replaced with the configuration of another embodiment, and the configuration of another embodiment can be added to the configuration of one embodiment. It is possible to add, delete, and replace other configurations for a part of the configuration of each embodiment.
- Solenoid valve 106 Liquid level sensor 107 ... Waste liquid tank 108 ... Cleaning liquid supply unit 109 ... Detergent supply unit 110 ... Waste liquid unit 111 ... Control unit 112 ; Cleaning liquid tank 113 ... Channel 114 ... Pump 115 ... Detergent tank 116 ... Channel 117 ... Pump 118 ... Channel 119 ... Waste liquid tank 120 Detergent container port 121 ... outer frame 122 ... disposal port 123 ... passage 1000 ... automatic analyzer
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Abstract
Description
以下、図1~図5を用いて、本発明の第1の実施形態である自動分析装置1000の構成及び動作を説明する。なお、一例として、血液、尿等の生体試料の分析を行う、ラックタイプの臨床検査用自動分析装置について説明するが、本発明はこれに限定されるものではない。
機構制御部20は、供給した洗浄液を洗剤貯留槽口120からオーバーフローさせて洗剤貯留槽101の内壁を洗浄する(step11)。具体的には、機構制御部20は、洗剤貯留槽101の所定時間だけ、洗剤タンク115から洗剤貯留槽101へ洗剤を送るポンプ117を駆動する。この所定時間は、例えば、ポンプ114を駆動し、洗剤貯留槽101の洗剤が空の状態から満タン(最大容量)の状態になるまでの時間より長い時間である。
次に、図6を用いて、本発明の第1の変形例である自動分析装置1000に用いられる洗剤貯留槽システム100Bの構成を説明する。図6は、本発明の第1の変形例である自動分析装置1000に用いられる洗剤貯留槽システム100Bの構成図である。なお、図6において、図2と同一部分には同一符号を付する。
次に、図7を用いて、本発明の第2の変形例である自動分析装置1000に用いられる洗剤貯留槽システム100Cの構成を説明する。図7は、本発明の第2の変形例である自動分析装置1000に用いられる洗剤貯留槽システム100Cの構成図である。なお、図7において、図6と同一部分には同一符号を付する。
次に、図8を用いて、本発明の第2の実施形態である自動分析装置1000に用いられる洗剤貯留槽ユニット13の構成を説明する。図8は、本発明の第2の実施形態である自動分析装置1000に用いられる洗剤貯留槽ユニット13の構成図(断面図)である。なお、図8において、図6と同一部分には同一符号を付する。
次に、図9を用いて、本発明の第3の実施形態である自動分析装置1000に用いられる洗剤貯留槽ユニット13の構成を説明する。図9は、本発明の第3の実施形態である自動分析装置1000に用いられる洗剤貯留槽ユニット13の上面図である。なお、図9において、図3と同一部分には同一符号を付する。図9は、図3の上面図に相当するものである。
次に、図10を用いて、本発明の第4の実施形態である自動分析装置1000に用いられる洗剤貯留槽ユニット13の構成を説明する。図10は、本発明の第4の実施形態である自動分析装置1000に用いられる洗剤貯留槽ユニット13の構成図(斜視図)である。なお、図10において、図3と同一部分には同一符号を付する。また、図10では、図面を見やすくするため、主要な部分のみを表示している。
2…反応容器
3…洗浄機構
4…光度計
5…撹拌機構
6…洗浄槽
7…試薬分注機構
8…洗浄槽
9…試薬ディスク
10…試薬ボトル
11…試料分注機構
12…洗浄槽
13…洗剤貯留槽ユニット
14…試料容器
15…ラック
16…試料搬送機構
17…試薬用ポンプ
18…試料用ポンプ
19…洗浄用ポンプ
20…機構制御部
21…表示部
100A、100B、100C…洗剤貯留槽システム
101…洗剤貯留槽
102…洗浄液供給口
103…洗剤供給口
104…廃液口
105…電磁弁
106…液面センサ
107…廃液槽
108…洗浄液供給部
109…洗剤供給部
110…廃液部
111…制御部
112…洗浄液タンク
113…流路
114…ポンプ
115…洗剤タンク
116…流路
117…ポンプ
118…流路
119…廃液タンク
120…洗剤貯留槽口
121…外枠
122…廃液口
123…流路
1000…自動分析装置
Claims (10)
- プローブを用いて試料を分注する試料分注機構と、
洗浄液供給口と洗剤供給口と廃液口を有し、前記プローブを洗浄するための洗剤を貯留するための洗剤貯留槽と、
洗浄液を蓄える洗浄液タンクと、
前記洗剤を蓄える洗剤タンクと、
廃液を蓄える廃液タンクと、
前記洗浄液タンクと前記洗浄液供給口を接続する流路上に設置された第1のポンプと、
前記洗剤タンクと前記洗剤供給口を接続する流路上に設置された第2のポンプと、
前記廃液口と前記廃液タンクとを接続する流路上に設置された電磁弁と、
前記洗剤貯留槽の洗浄が実行されるための所定条件を満たさず、かつ、前記洗剤貯留槽に貯留された洗剤の残量が所定量以下の場合、第2のポンプを駆動し、前記洗剤の残量を所定量にする第1の制御と、
前記洗剤貯留槽の洗浄が実行されるための所定条件を満たした場合、前記電磁弁を開いて前記洗剤貯留槽内の洗剤を廃液し、前記洗剤貯留槽内の洗剤が廃液された後、前記電磁弁を閉じて前記第1のポンプを駆動し、前記洗浄水を前記洗剤貯留槽へ供給する第2の制御を実行する制御部と、
を備えることを特徴とする自動分析装置。 - 請求項1に記載の自動分析装置であって、
前記制御部は、
前記第1の制御及び前記第2の制御を実行する間であっても、前記試料の分析を行う
ことを特徴とする自動分析装置。 - 請求項2に記載の自動分析装置であって、
前記制御部は、
前記第2の制御により前記洗剤貯留槽から前記洗浄水をオーバーフローさせた後、前記電磁弁を開いて前記洗剤貯留槽内の洗浄液を廃液する
ことを特徴とする自動分析装置。 - 請求項3に記載の自動分析装置であって、
前記制御部は、
前記試料の分注を一時停止した後、前記第2の制御を実行し、
前記電磁弁を開いて前記洗剤貯留槽内の洗浄液を廃液した後、第2のポンプを駆動し、前記洗剤の残量を所定量とし、
前記洗剤の残量が所定量になった後、前記試料の分注を再開する
ことを特徴とする自動分析装置。 - 請求項1に記載の自動分析装置であって、
前記洗浄液供給口は、
前記洗剤貯留槽において、前記洗剤供給口よりも上に設置される
ことを特徴とする自動分析装置。 - 請求項5に記載の自動分析装置であって、
前記洗剤供給口は、
前記洗剤貯留槽の下側端部に設置される
ことを特徴とする自動分析装置。 - 請求項1に記載の自動分析装置であって、
前記洗剤貯留槽は、
その内周面にらせん状の溝を備える
ことを特徴とする自動分析装置。 - 請求項1に記載の自動分析装置であって、
前記洗浄液供給口は、
前記洗剤貯留槽の軸に垂直な断面の中心に対して点対象となる位置に少なくとも2つ配置される
ことを特徴とする自動分析装置。 - 請求項1に記載の自動分析装置であって、
前記洗剤貯留槽に隣接し、前記洗剤貯留槽からオーバーフローした洗浄水を廃棄するための廃液槽を備える
ことを特徴とする自動分析装置。 - 請求項1に記載の自動分析装置であって、
前記洗剤貯留槽の洗浄が実行されるための所定条件を設定する操作画面を表示する表示部を備える
ことを特徴とする自動分析装置。
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