WO2014143931A3 - Multi-biomarker biosensor - Google Patents

Multi-biomarker biosensor Download PDF

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Publication number
WO2014143931A3
WO2014143931A3 PCT/US2014/028118 US2014028118W WO2014143931A3 WO 2014143931 A3 WO2014143931 A3 WO 2014143931A3 US 2014028118 W US2014028118 W US 2014028118W WO 2014143931 A3 WO2014143931 A3 WO 2014143931A3
Authority
WO
WIPO (PCT)
Prior art keywords
biosensor
biomarker
nanosubstrates
methods
biosensors
Prior art date
Application number
PCT/US2014/028118
Other languages
French (fr)
Other versions
WO2014143931A2 (en
Inventor
Asanterabi Malima
Ahmed Busnaina
Salome Siavoshi
Sivasubramanian Somu
Cihan Yilmaz
Tiziana Musacchio
Jaydev Upponi
Vladimir Torchilin
Original Assignee
Northeastern University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/840,772 external-priority patent/US20130330747A1/en
Application filed by Northeastern University filed Critical Northeastern University
Priority to EP14764307.6A priority Critical patent/EP2972362A4/en
Publication of WO2014143931A2 publication Critical patent/WO2014143931A2/en
Publication of WO2014143931A3 publication Critical patent/WO2014143931A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346—Nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14503—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/1459—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1473—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6852—Catheters
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites

Abstract

Nanosubstrates as biosensors, methods of making such nanosubstrates, and methods of using such nanosubstrates to detect biomarkers are described.
PCT/US2014/028118 2013-03-15 2014-03-14 Multi-biomarker biosensor WO2014143931A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP14764307.6A EP2972362A4 (en) 2013-03-15 2014-03-14 Multi-biomarker biosensor

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/840,772 2013-03-15
US13/840,772 US20130330747A1 (en) 2005-12-01 2013-03-15 Multi-biomarker biosensor

Publications (2)

Publication Number Publication Date
WO2014143931A2 WO2014143931A2 (en) 2014-09-18
WO2014143931A3 true WO2014143931A3 (en) 2015-11-05

Family

ID=51538287

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2014/028118 WO2014143931A2 (en) 2013-03-15 2014-03-14 Multi-biomarker biosensor

Country Status (2)

Country Link
EP (1) EP2972362A4 (en)
WO (1) WO2014143931A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070264634A1 (en) * 2002-10-10 2007-11-15 Nanosys, Inc. Nano-chem-fet based biosensors
US20110117582A1 (en) * 2005-12-01 2011-05-19 Northeastern University Multi-biomarker biosensor
US20110257504A1 (en) * 2005-08-31 2011-10-20 Biotectix, LLC Biologically integrated electrode devices

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5605662A (en) * 1993-11-01 1997-02-25 Nanogen, Inc. Active programmable electronic devices for molecular biological analysis and diagnostics

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070264634A1 (en) * 2002-10-10 2007-11-15 Nanosys, Inc. Nano-chem-fet based biosensors
US20110257504A1 (en) * 2005-08-31 2011-10-20 Biotectix, LLC Biologically integrated electrode devices
US20110117582A1 (en) * 2005-12-01 2011-05-19 Northeastern University Multi-biomarker biosensor

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP2972362A4 *

Also Published As

Publication number Publication date
WO2014143931A2 (en) 2014-09-18
EP2972362A2 (en) 2016-01-20
EP2972362A4 (en) 2016-11-23

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