WO2014138426A3 - Methods and compositions for reducing body fat and adipocytes - Google Patents
Methods and compositions for reducing body fat and adipocytes Download PDFInfo
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- WO2014138426A3 WO2014138426A3 PCT/US2014/021288 US2014021288W WO2014138426A3 WO 2014138426 A3 WO2014138426 A3 WO 2014138426A3 US 2014021288 W US2014021288 W US 2014021288W WO 2014138426 A3 WO2014138426 A3 WO 2014138426A3
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- WIPO (PCT)
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- adipocytes
- compositions
- methods
- body fat
- reducing body
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- A—HUMAN NECESSITIES
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
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- A61K31/11—Aldehydes
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
- A61K31/198—Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
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- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
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- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
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- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
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- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
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- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/074—Ganoderma
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Abstract
Provided are methods and compositions for reducing body fat, and/or adipocytes in a subject, comprising administering a compound and/or natural product extract that is an activator of adenosine monophosphate-activated kinase (AMPK).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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US201361773942P | 2013-03-07 | 2013-03-07 | |
US61/773,942 | 2013-03-07 |
Publications (2)
Publication Number | Publication Date |
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WO2014138426A2 WO2014138426A2 (en) | 2014-09-12 |
WO2014138426A3 true WO2014138426A3 (en) | 2014-10-30 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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PCT/US2014/021288 WO2014138426A2 (en) | 2013-03-07 | 2014-03-06 | Methods and compositions for reducing body fat and adipocytes |
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WO (1) | WO2014138426A2 (en) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK3009138T3 (en) * | 2014-09-01 | 2019-08-05 | Vidya Herbs Pvt Ltd | MANGIFERA EXTRACT FOR MANAGING OBES AND / OR WEIGHT |
EP3124047A1 (en) * | 2015-07-28 | 2017-02-01 | Merz Pharma GmbH & Co. KGaA | Pentacyclic triterpenoids for injection lipolysis |
AU2016314546C1 (en) * | 2015-08-28 | 2021-07-22 | Caliway Biopharmaceuticals Co., Ltd. | Pharmaceutical composition used for reducing localised fat and use of pharmaceutical composition |
US11318110B2 (en) | 2015-08-28 | 2022-05-03 | Caliway Biopharmaceuticals Co., Ltd. | Pharmaceutical composition for reducing local fat and uses thereof |
US10369179B2 (en) | 2015-09-13 | 2019-08-06 | Vidya Herbs, Inc. | Composition of Mangifera indica |
FR3042411B1 (en) * | 2015-10-20 | 2019-07-12 | Valbiotis | COMPOSITION COMPRISING A MIXTURE OF PARTICULAR MOLECULES AND USE FOR ACTING ON GLUCIDIC AND / OR LIPID METABOLISM |
CA3033041A1 (en) * | 2016-08-26 | 2018-03-01 | Caliway Biopharmaceuticals Co., Ltd. | A subcutaneous injection formulation for reducing body weight and uses thereof |
US11896600B2 (en) | 2019-09-21 | 2024-02-13 | Vidya Herbs, Inc. | Composition and method of using eicosanoyl-5-hydroxytryptamide for treating neurodegenerative disorders |
US11452703B2 (en) * | 2020-05-21 | 2022-09-27 | Peregrine Ophthalmic PTE LTD. | Methods and compositions for reducing adipocyte numbers |
Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020136785A1 (en) * | 2000-11-07 | 2002-09-26 | Chun-Su Yuan | Ginseng berry extracts and pharmaceutical compositions from ginseng berry for the treatment of type 2 diabetes and obesity |
WO2003011267A1 (en) * | 2001-07-31 | 2003-02-13 | The Nisshin Oillio, Ltd. | Antiobesity drugs and materials thereof |
US20030212014A1 (en) * | 2000-08-09 | 2003-11-13 | Neil Ruderman | Methods fo treating conditions associated with insulin resistance with aicar, (5-amino-4-imidazole carboxamide riboside) and related compounds |
US20050171027A1 (en) * | 2003-12-29 | 2005-08-04 | President And Fellows Of Harvard College | Compositions for treating or preventing obesity and insulin resistance disorders |
US20050267221A1 (en) * | 2004-05-14 | 2005-12-01 | Research Development Foundation | Use of curcumin and analogues thereof as inhibitors of ACC2 |
WO2007081808A2 (en) * | 2006-01-05 | 2007-07-19 | Deviris Inc. | Compounds and derivatives for the treatment of medical conditions by modulating hormone-sensitive lipase activity |
US20080004217A1 (en) * | 1998-12-30 | 2008-01-03 | Applied Research Systems Ars | Treatment of hiv-associated dysmorphia/dysmetabolic syndrome (hadds) with or without lipodystrophy |
US20100152275A1 (en) * | 2008-12-11 | 2010-06-17 | Kaloness, Inc. | Drug or Supplement Combination with Conjugated Linoleic Acid for Fat Loss in Mammals |
WO2011152692A2 (en) * | 2010-06-03 | 2011-12-08 | 주식회사 리스토어랩스 | Anti-obesity cream composition containing fucoxanthin |
TW201231046A (en) * | 2011-01-25 | 2012-08-01 | Univ Nat Cheng Kung | Pharmaceutical composition or Toona sinensis extract for decreasing weight or body fat |
-
2014
- 2014-03-06 WO PCT/US2014/021288 patent/WO2014138426A2/en active Application Filing
Patent Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080004217A1 (en) * | 1998-12-30 | 2008-01-03 | Applied Research Systems Ars | Treatment of hiv-associated dysmorphia/dysmetabolic syndrome (hadds) with or without lipodystrophy |
US20030212014A1 (en) * | 2000-08-09 | 2003-11-13 | Neil Ruderman | Methods fo treating conditions associated with insulin resistance with aicar, (5-amino-4-imidazole carboxamide riboside) and related compounds |
US20020136785A1 (en) * | 2000-11-07 | 2002-09-26 | Chun-Su Yuan | Ginseng berry extracts and pharmaceutical compositions from ginseng berry for the treatment of type 2 diabetes and obesity |
WO2003011267A1 (en) * | 2001-07-31 | 2003-02-13 | The Nisshin Oillio, Ltd. | Antiobesity drugs and materials thereof |
US20050171027A1 (en) * | 2003-12-29 | 2005-08-04 | President And Fellows Of Harvard College | Compositions for treating or preventing obesity and insulin resistance disorders |
US20050267221A1 (en) * | 2004-05-14 | 2005-12-01 | Research Development Foundation | Use of curcumin and analogues thereof as inhibitors of ACC2 |
WO2007081808A2 (en) * | 2006-01-05 | 2007-07-19 | Deviris Inc. | Compounds and derivatives for the treatment of medical conditions by modulating hormone-sensitive lipase activity |
US20100152275A1 (en) * | 2008-12-11 | 2010-06-17 | Kaloness, Inc. | Drug or Supplement Combination with Conjugated Linoleic Acid for Fat Loss in Mammals |
WO2011152692A2 (en) * | 2010-06-03 | 2011-12-08 | 주식회사 리스토어랩스 | Anti-obesity cream composition containing fucoxanthin |
TW201231046A (en) * | 2011-01-25 | 2012-08-01 | Univ Nat Cheng Kung | Pharmaceutical composition or Toona sinensis extract for decreasing weight or body fat |
Non-Patent Citations (20)
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WO2014138426A2 (en) | 2014-09-12 |
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