WO2014095381A1 - Fungicidal imidazolyl and triazolyl compounds - Google Patents

Abstract

The present invention relates to fungicidal imidazolyl and triazolyl compounds (I), agrochemical compositions comprising them, to their use and to methods for combating phytopathogenic fungi. The present invention also relates to seeds treated with at least one such compound. Furthermore the invention relates to processes for preparing compounds of formula I as well as to specific intermediates that are obtained during the reaction sequence.

Description

Fungicidal imidazolyl and triazolyl compounds

The present invention relates to fungicidal imidazolyl and triazolyl compounds, agrochemical compositions comprising them, to their use and to methods for combating phytopathogenic fungi. The present invention also relates to seeds treated with at least one such compound. Furthermore the invention relates to processes for preparing compounds of formula I as well as to specific intermediates that are obtained during the reaction sequence.

US 4664696 A relates to a-phenyl- or benzyl-a-cyclopropylalkylene-1 H-imidazole- and 1 ,2,4-triazole-1 -ethanols and their use against fungi. DE 3337937 A1 describes similar triazole fungicides, their use in agriculture and on humans as well as compositions comprising them. WO 96/16048 A1 relates to microbicidal triazolyl-derivatives, their preparation and to their use for protection of plants and materials.

In many cases, in particular at low application rates, the fungicidal activity of known fungicidal compounds is unsatisfactory. Based on this, it was an object of the present invention to provide compounds having improved activity and/or a broader activity spectrum against phytopathogenic fungi. This objective is achieved by the use of substituted imidazolyl and triazolyl compounds of formula I having good fungicidal activity against phytopathogenic fungi.

The compounds according to the present invention differ from those described in the abovementioned publications in that the divalent methylene group adjacent to the triazole or imidazole ring carries at least one further substituent.

Accordingly, the present of the formula I

(R⁴)n

wherein:

A is N or CH;

D is hydrogen, halogen or SR^D; wherein

R^D is hydrogen, CN, d-C₆-alkyl, Ci-C₆-haloalkyl, C₂-C₆-alkenyl,

C2-C6-haloalkenyl, C2-C6-alkynyl or C2-C6-haloalkynyl; is halogen, CN, N0₂, OH, SH, Ci-C₆-alkyl, Ci-C₆-alkoxy, Ci-C₆-alkylthio, Ci-C₆- alkylsulfinyl, Ci-C6-alkylsulfonyl, C2-C6-alkenyl, C2-C6-alkynyl, C₃-C8-cycloalkyl, Cs-Cs-cycloalkoxy, C₃-C₈-cycloalkyl-Ci-C₄-alkyl, NH₂, NH(Ci-C₄-alkyl), N(Ci-C₄- alkyl)₂, NH(C₃-C₆-cycloalkyl), N(C₃-C₆-cycloalkyl)₂, C(=0)-Ci-C₄-alkyl, C(=0)OH, C(=0)-0-Ci-C₄-alkyl, C(=0)-NH(Ci-C₄-alkyl), C(=0)-N(Ci-C₄-alkyl)₂,

C(=0)-NH(C₃-C₆-cycloalkyl), C(=0)-N(C₃-C₆-cycloalkyl)₂, phenyl, heteroaryl, phenyl-Ci-C₄-alkyl or heteroaryl-Ci-C₄-alkyl, wherein the heteroaryl radical in the last-mentioned groups is 5- or 6-membered; and wherein the aliphatic, alicyclic and aromatic moieties of R¹ are unsubstituted or substituted by one, two, three or four or up to the maximum possible number of independently selected

substituents R^1a; wherein is halogen, CN, N0₂, OH, SH, NH₂, Ci-C₆-alkyl, Ci-C₆-haloalkyl, Ci-C₆-alk- oxy, Ci-C6-haloalkoxy, Ci-C6-alkylthio, Ci-C6-haloalkylthio, C₃-C8-cycloalkyl or Ci-C₄-alkoxy-Ci-C₄-alkyl;

R² is hydrogen, halogen, CN, N0₂, OH, SH, Ci-C₆-alkyl, Ci-C₆-alkoxy, Ci-C₆- alkylthio, Ci-C6-alkylsulfinyl, Ci-C6-alkylsulfonyl, C₂-C6-alkenyl, C₂-C6-alkynyl, C₃-C8-cycloalkyl, C₃-C8-cycloalkyloxycycloalkoxy, NH₂, NH(Ci-C₄-alkyl), N(Ci-C₄- alkyl)₂, NH(C₃-C₆-cycloalkyl), N(C₃-C₆-cycloalkyl)₂, C(=0)-Ci-C₄-alkyl, C(=0)OH,

C(=0)-0-Ci-C₄-alkyl, C(=0)-NH(Ci-C₄-alkyl), C(=0)-N(Ci-C₄-alkyl)₂, C(=0)- NH(C₃-C6-cycloalkyl), C(=0)-N(C₃-C6-cycloalkyl)₂, phenyl, heteroaryl, phenyl- Ci-C₄-alkyl or heteroaryl-Ci-C₄-alkyl, wherein the heteroaryl group in the last- mentioned groups is 5- or 6-membered; and wherein the aliphatic, alicyclic and aromatic moieties of R² are unsubstituted or substituted by one, two, three or four or up to the maximum possible number of independently selected substituents R^2a; wherein

R^2a is halogen, CN, N0₂, OH, SH, NH₂, Ci-C₆-alkyl, Ci-C₆-haloalkyl, Ci-C₆-alk- oxy, Ci-C6-haloalkoxy, Ci-C6-alkylthio, Ci-C6-haloalkylthio, C₃-C8-cycloalkyl or Ci-C₄-alkoxy-Ci-C₄-alkyl; or R¹ and R² together with the carbon atom to which they are bound (denominated as C^*) form a vinyl group C^*=CR¹¹R²², wherein

R¹¹ and R²² are independently selected from the group consisting of

hydrogen, halogen, CN, N0₂, OH, SH, NH₂, d-C₆-alkyl, Ci-C₆-haloalkyl, Ci-C6-alkoxy, Ci-C6-haloalkoxy, Ci-C6-alkylthio, Ci-C6-haloalkylthio and C 1 -C₄-a I koxy-C 1 -C₄-a I ky I ; or R¹ and R² together with the carbon atom to which they are bound form a saturated or partially unsaturated three-, four-, five-, six- or seven-membered carbocycle or a saturated or partially unsaturated three-, four-, five-, six- or seven-membered heterocycle, wherein the heterocycle includes beside carbon atoms one, two, three or four heteroatoms independently selected from the group consisting of N, O and S, and wherein the carbo- and heterocycle are unsubstituted or carry one, two, three or four independently selected substituents R¹², wherein one or two CH₂ groups of the carbo- or heterocycle may be replaced by one or two groups independently selected from the group of C(=0) and C(=S);

wherein

R¹² is halogen, CN, N0₂, OH, SH, NH₂, Ci-C₆-alkyl, Ci-C₆-haloalkyl,

d-Ce-alkoxy, Ci-C₆-haloalkoxy, Ci-C₆-alkylthio, Ci-C₆-haloalkylthio, Ci-C₄- alkoxy-Ci-C₄-alkyl, phenyl or phenoxy; wherein the phenyl moieties of R¹² are unsubstituted or substituted by one, two, three or four independently selected substituents R^12a; wherein

R ^2a is halogen, CN, N0₂, OH, SH, NH₂, Ci-C₆-alkyl, Ci-C₆-haloalkyl,

Ci-C6-alkoxy, Ci-C6-haloalkoxy, Ci-C6-alkylthio, Ci-C6-haloalkylthio, C3-C8-cycloalkyl or Ci-C₄-alkoxy-Ci-C₄-alkyl;

X is OR³ or CN; wherein

R³ is hydrogen, Ci-C6-alkyl, C₂-C6-alkenyl, C₂-C6-alkynyl, C₂-C6-alkynyl, C₃-C₃- cycloalkyl, Ci-C₆-alkylsulfonyl, phenylsulfonyl, C(=0)-Ci-C₄-alkyl, C(=0)-0- Ci-C₄-alkyl, C(=0)-NH(Ci-C₄-alkyl), C(=0)-N(Ci-C₄-alkyl)₂,

alkylphenyl, phenyl, phenyl-Ci-C₄-alkyl, phenyl-C₂-C₄-alkenyl or phenyl- C₂-C₄-alkynyl; wherein the aliphatic, alicyclic and aromatic moieties of R³ are unsubstituted or substituted by one, two, three or four or up to the maximum possible number of independently selected substituents R^3a; wherein R^3a is halogen, CN, N0₂, OH, C C₄-alkyl, C C₄-halogenalkyl, C₃-C₈- cycloalkyl, Ci-C₄-alkoxy or Ci-C₄-halogenalkoxy;

R⁴ is independently selected from the group consisting of halogen, CN, N0₂, OH, SH, d-Ce-alkyl, Ci-C₆-alkoxy, Ci-C₆-alkylthio, Ci-C₆-alkylsulfinyl, Ci-C₆- alkylsulfonyl, C₂-C6-alkenyl, C₂-C6-alkynyl, C₃-C8-cycloalkyl, C₃-C8-cycloalkyloxy,

NH₂, NH(Ci-C₄-alkyl), N(Ci-C₄-alkyl)₂, NH(C₃-C₆-cycloalkyl), N(C₃-C₆-cycloalkyl)₂, C(=0)-Ci-C₄-alkyl, C(=0)OH,

C(=0)-0-Ci-C₄-alkyl, C(=0)-NH(Ci-C₄-alkyl), C(=0)-N(Ci-C₄-alkyl)₂,

C(=0)-NH(C₃-C₆-cycloalkyl) and C(=0)-N(C₃-C₆-cycloalkyl)₂; wherein the aliphatic and alicyclic moieties of R⁴ are unsubstituted or substituted by one, two, three or four or up to the maximum possible number of independently selected substituents R^4a; wherein R^4a is halogen, CN, N0₂, OH, C C₄-alkyl, C C₄-haloalkyl, C₃-C₈-cycloalkyl, Ci-C₄-alkoxy or Ci-C₄-halogenalkoxy; is 0, 1 , 2, 3 or 4; is a direct bond or a divalent radical selected from -0-, -S(=0)_p-, -CR^Y1R^Y2-, -N(R^YN)-, -CR^Y3R^Y4-CR^Y5R^Y6-, -CR^Y7=C^Y8- and -C≡C-, wherein

R^YN, R^Y , R^Y2, R^Y3, R^Y4, R^Y5, R^Y6, R^Y7 and R^Y8 are independently selected from the group consisting of hydrogen, halogen, CN, nitro, OH, Ci-C₄-alkyl,

Ci-C₄-halogenalkyl, Ci-C₄-alkoxy and Ci-C₄-halogenalkoxy; p is 0, 1 or 2; is phenyl or a five- or six-membered heteroaryl, wherein the aromatic moiety is unsubstituted or carries one, two, three or four independently selected radicals R^L; wherein is halogen, CN, N0₂, OH, SH, Ci-Ce-alkyl, Ci-C₆-alkoxy, Ci-C₆-alkylthio, Ci-C6-alkylsulfinyl, Ci-C6-alkylsulfonyl, C2-C6-alkenyl, C2-C6-alkynyl, C₃-C₃- cycloalkyl, C₃-C8-cycloalkyloxy, C3-C8-cycloalkyl-Ci-C₄-alkyl, NH2, NH(Ci-C₄-alkyl), N(Ci-C₄-alkyl)₂, NH(C₃-C₆-cycloalkyl), N(C₃-C₆-cycloalkyl)₂, C(=0)-Ci-C₄-alkyl, C(=0)OH, C(=0)-0-Ci-C₄-alkyl, C(=0)-NH(Ci-C₄-alkyl), C(=0)-N(Ci-C₄-alkyl)₂, C(=0)-NH(C₃-C6-cycloalkyl), C(=0)-N(C₃-C₆- cycloalkyl)2, phenyl and phenyl-Ci-C₄-alkyl; and wherein the aliphatic, alicyclic and aromatic moieties are unsubstituted or substituted by one, two, three or four or up to the maximum possible number of independently selected substituents R^La; wherein

R^La is halogen, CN, N0₂, OH, SH, NH₂, Ci-Ce-alkyl, Ci-C₆-haloalkyl,

Ci-C6-alkoxy, Ci-C6-haloalkoxy, Ci-C6-alkylthio, Ci-C6-haloalkylthio or C₃-C8-cycloalkyl; m is 0 or 1 ;

R⁵ and R⁶ are independently selected from the group consisting of hydrogen, halogen, CN, N0₂, OH, SH, Ci-Ce-alkyl, Ci-C₆-alkoxy, Ci-C₆-alkylthio, Ci-Ce-alkylsulfinyl, Ci-C6-alkylsulfonyl, C2-C6-alkenyl, C2-C6-alkynyl, C₃-C8-cycloalkyl, C₃-Cs- cycloalkoxy, NH₂, NH(Ci-C₄-alkyl), N(Ci-C₄-alkyl)₂, NH(C₃-C₆-cycloalkyl), N(C₃-C₆-cycloalkyl)₂, C(=0)-Ci-C₄-alkyl, C(=0)OH, C(=0)-0-Ci-C₄-alkyl,

C(=0)-NH(Ci-C₄-alkyl) or C(=0)-N(Ci-C₄-alkyl)₂, C(=0)-NH(C₃-C₆-cycloalkyl) and C(=0)-N(C₃-C6-cycloalkyl)2; wherein the aliphatic and alicyclic moieties of R⁵ and/or R⁶ are unsubstituted or substituted by one, two, three or four or up to the maximum possible number of independently selected substituents R⁵¹; wherein

R⁵¹ is halogen, CN, N0₂, OH, SH, NH₂, Ci-C₆-alkyl, Ci-C₆-haloalkyl,

Ci-C6-alkoxy, Ci-C6-haloalkoxy, Ci-C6-alkylthio, Ci-C6-haloalkylthio, C3-C8- cycloalkyl and Ci-C4-alkoxy-Ci-C4-alkyl; or R⁵ and R⁶ together with the carbon atom to which they are bound form a saturated or partially unsaturated three-, four-, five-, six- or seven-membered carbocycle or a saturated or partially unsaturated three-, four-, five-, six- or seven-membered heterocycle, wherein the heterocycle includes beside carbon atoms one, two, three or four heteroatoms independently selected from the group consisting of N, O and S, and wherein the carbo- and heterocycle are unsubstituted or carry one, two, three or four independently selected substituents R⁵⁶, wherein one or two CH2 groups of the carbo- or heterocycle may be replaced by one or two groups independently selected from the group of C(=0) and C(=S);

wherein

R⁵⁶ is halogen, CN, N0₂, OH, SH, NH₂, Ci-C₆-alkyl, Ci-C₆-haloalkyl,

Ci-C6-alkoxy, Ci-C6-haloalkoxy, Ci-C6-alkylthio, Ci-C6-haloalkylthio or

C 1 -C₄-a I koxy-C 1 -C₄-a I ky I ; or R⁵ and R⁶ together with the carbon atom to which they are bound (denominated as C^*) form a vinyl group C^*=CR⁵²R⁵³, wherein

R⁵² and R⁵³ are independently selected from the group consisting of

hydrogen, halogen, CN, N0₂, OH, SH, NH₂, Ci-C₆-alkyl, d-C₆-haloalkyl, Ci-C6-alkoxy, Ci-C6-haloalkoxy, Ci-C6-alkylthio, Ci-C6-haloalkylthio and C 1 -C₄-a I koxy-C 1 -C₄-a I ky I ; or R⁵ and R⁶ together with the carbon atom to which they are bound (denominated as C^*) form a group selected from C^*(=S), C^*(=0) and C^*(=NOR"); wherein

R" is hydrogen, Ci-C6-alkyl, Ci-C6-haloalkyl, C2-C6-alkenyl, C2-C6-alkynyl or Ci-C -alkoxy-Ci-C -alkyl;

R⁷ is hydrogen, halogen, CN, Ci-C6-alkyl, Ci-C6-haloalkyl, Ci-C6-alkoxy or C1-C6- haloalkoxy; and the N-oxides and the agriculturally acceptable salts of the compounds

of formula I.

The present invention also provides a use of compounds I and/or their agriculturally useful salts for controlling phytopathogenic fungi and to methods for combating phytopathogenic fungi. The invention further provides compositions comprising these compounds I and/or their agriculturally acceptable salts. The present invention also relates to seeds treated with at least one such compound. Furthermore the invention relates to processes for preparing compounds of formula I and to intermediates such as compounds of formulae IV, V and VI.

Compounds I can exist as one or more stereoisomers. The various stereoisomers include enantiomers, diastereomers, atropisomers and geometric isomers. One skilled in the art will appreciate that one stereoisomer may be more active and/or may exhibit beneficial effects when enriched relative to the other stereoisomer(s) or when separated from the other stereoisomer(s). Additionally, the skilled artisan knows how to separate, enrich, and/or to selectively prepare said stereoisomers. The compounds of the invention may be present as a mixture of stereoisomers, e.g. a racemate, individual stereoisomers, or as an optically active form.

Compounds I can be present in different crystal modifications whose biological activity may differ. They also form part of the subject matter of the present invention. The compounds of formula I can be present in atropisomers arising from restricted rotation about a single bond of asymmetric groups. They also form part of the subject matter of the present invention.

In respect of the variables, the embodiments of the intermediates correspond to the embodiments of the compounds of formula I. The term "compounds I" refers to compounds of formula I.

In the definitions of the variables given above, collective terms are used which are generally representative for the substituents in question. The term "C_n-C_m" indicates the number of carbon atoms possible in each case in the substituent or substituent moiety in question.

The term "halogen" refers to fluorine, chlorine, bromine and iodine.

The term "Ci-C6-alkyl" refers to a straight-chained or branched saturated hydrocarbon group having 1 to 6 carbon atoms, for example methyl, ethyl, propyl, 1 -methylethyl, butyl, 1 -methylpropyl, 2-methylpropyl, and 1 ,1 -dimethylethyl.

The term "Ci-C6-haloalkyl" refers to a straight-chained or branched alkyl group having 1 to 6 carbon atoms (as defined above), wherein some or all of the hydrogen atoms in these groups may be replaced by halogen atoms as mentioned above, for example chloromethyl, bromomethyl, dichloromethyl, trichloromethyl, fluoromethyl, difluoro- methyl, trifluoromethyl, chlorofluoromethyl, dichlorofluoromethyl, chlorodifluoromethyl, 1 -chloroethyl, 1 -bromoethyl, 1 -fluoroethyl, 2-fluoroethyl, 2,2-difluoroethyl, 2,2,2-tri- fluoroethyl, 2-chloro-2 -fluoroethyl, 2-chloro-2,2-difluoroethyl, 2,2-dichloro-2-fluoroethyl, 2,2,2-trichloroethyl and pentafluoroethyl, 2-fluoropropyl, 3-fluoropropyl, 2,2-difluoro- propyl, 2,3-difluoropropyl, 2-chloropropyl, 3-chloropropyl, 2,3-dichloropropyl, 2-bromo- propyl, 3-bromopropyl, 3,3,3-trifluoropropyl, 3,3,3-trichloropropyl, CH2-C2F5, CF2-C2F5, CF(CF3)2, 1 -(fluoromethyl)-2 -fluoroethyl, 1 -(chloromethyl)-2-chloroethyl, 1 -(bromo- methyl)-2-bromoethyl, 4-fluorobutyl, 4-chlorobutyl, 4-bromobutyl or nonafluorobutyl.

The term "Ci-C6-alkoxy" refers to a straight-chain or branched alkyl group having 1 to 6 carbon atoms (as defined above) which is bonded via an oxygen, at any position in the alkyl group, for example methoxy, ethoxy, n-propoxy, 1 -methylethoxy, butoxy, 1 -meth- yhpropoxy, 2-methylpropoxy or 1 ,1 -dimethylethoxy.

The term "Ci-C6-hydroxyalkyl" refers to a straight-chained or branched alkyl group having 1 to 6 carbon atoms (as defined above), wherein one hydrogen atom in these groups may be replaced by one hydroxy group, for example hydroxym ethyl,

2-hydroxyethyl, 3-hydroxy-propyl, 4-hydroxy-butyl.

The term "Ci-C6-haloalkoxy" refers to a Ci-C6-alkoxy group as defined above, wherein some or all of the hydrogen atoms may be replaced by halogen atoms as mentioned above, for example, OCH₂F, OCHF₂, OCF₃, OCH₂CI, OCHC , OCCI₃, chlorofluoro- methoxy, dichlorofluoromethoxy, chlorodifluoromethoxy, 2-fluoroethoxy, 2-chloro- ethoxy, 2-bromoethoxy, 2-iodoethoxy, 2,2-difluoroethoxy, 2,2,2-trifluoroethoxy, 2-chloro-2-fluoroethoxy, 2-chloro-2,2-difluoroethoxy, 2,2-dichloro-2-fluoroethoxy, 2,2,2-trichloroethoxy, OC2F5, 2-fluoropropoxy, 3-fluoropropoxy, 2,2-difluoropropoxy, 2,3-difluoropropoxy, 2-chloropropoxy, 3-chloropropoxy, 2,3-dichloropropoxy,

2-bromopropoxy, 3-bromopropoxy, 3,3,3-trifluoropropoxy, 3,3,3-trichloropropoxy, OCH₂-C₂F₅, OCF₂-C₂F₅, 1 -(CH₂F)-2-fluoroethoxy, 1 -(CH₂CI)-2-chloroethoxy, 1 -(CH₂Br)- 2-bromo^-,ethoxy, 4-fluorobutoxy, 4-chlorobutoxy, 4-bromobutoxy or nonafluorobutoxy. The term "Ci-C4-alkoxy-Ci-C4-alkyl" refers to alkyl having 1 to 4 carbon atoms (as defined above), wherein one hydrogen atom of the alkyl radical is replaced by a Ci-C4-alkoxy group (as defined above). Likewise, the term "Ci-C6-alkoxy-Ci-C4-alkyl" refers to alkyl having 1 to 4 carbon atoms (as defined above), wherein one hydrogen atom of the alkyl radical is replaced by a Ci-C6-alkoxy group (as defined above).

The term "Ci-C6-alkylthio" as used herein refers to straight-chain or branched alkyl groups having 1 to 6 carbon atoms (as defined above) bonded via a sulfur atom.

Accordingly, the term "Ci-C6-haloalkylthio" as used herein refers to straight-chain or branched haloalkyl group having 1 to 6 carbon atoms (as defined above) bonded through a sulfur atom, at any position in the haloalkyl group.

The term "Ci -C6-a I kylsu If i nyl " refers to straight-chain or branched alkyl groups having 1 to 6 carbon atoms (as defined above) bonded through a -S(=0)- moiety, at any position in the alkyl group, for example methylsulfinyl and ethylsulfinyl, and the like.

Accordingly, the term "Ci-C6-haloalkylsulfinyl" refers to straight-chain or branched haloalkyl group having 1 to 6 carbon atoms (as defined above), bonded through a -S(=0)- moiety, at any position in the haloalkyl group.

The term "Ci-C6-alkylsulfonyl" refers to straight-chain or branched alkyl groups having 1 to 6 carbon atoms (as defined above), bonded through a -S(=0)2- moiety, at any position in the alkyl group, for example methylsulfonyl. Accordingly, the term

"Ci-C6-haloalkylsulfonyl" refers to straight-chain or branched haloalkyl group having 1 to 6 carbon atoms (as defined above), bonded through a -S(=0)2- moiety, at any position in the haloalkyl group.

The term "C2-C6-alkenyl" refers to a straight-chain or branched unsaturated

hydrocarbon radical having 2 to 6 carbon atoms and a double bond in any position, such as ethenyl, 1 -propenyl, 2-propenyl (allyl), 1 -methylethenyl, 1 -butenyl, 2-butenyl, 3-butenyl, 1 -methyl-1 -propenyl, 2-methyl-1 -propenyl, 1 -methyl-2-propenyl, 2-methyl-2- propenyl.

The term "C2-C6-alkynyl" refers to a straight-chain or branched unsaturated

hydrocarbon radical having 2 to 6 carbon atoms and containing at least one triple bond, such as ethynyl, 1 -propynyl, 2-propynyl (propargyl), 1 -butynyl, 2-butynyl, 3-butynyl, 1 -methyl-2-propynyl.

The term "Cs-Cs-cycloalkyl" refers to monocyclic saturated hydrocarbon radicals having 3 to 8 carbon ring members, such as cyclopropyl (C3H5), cyclobutyl, cyclopentyl, cyclohexyl, cycloheptyl or cyclooctyl.

The term "C3-C8-cycloalkyl-Ci-C4-alkyl" refers to a cycloalkyl radical having 3 to 8 carbon atoms (as defined above), which is bonded via a Ci-C4-alkyl group (as defined above).

The term "Cs-Cs-cycloalkyl-Cs-Cs-cycloalkyl" refers to a cycloalkyl radical having 3 to 8 carbon atoms (as defined above), which is substituted by a further cycloalkyl radical having 3 to 8 carbon atoms.

The term "Cs-Cs-cycloalkoxy" refers to a cycloalkyl radical having 3 to 8 carbon atoms (as defined above), which is bonded via an oxygen.

The term "C(=0)-Ci-C4-alkyl" refers to a radical which is attached through the carbon atom of the group C(=0) as indicated by the number valence of the carbon atom. The number of valence of carbon is 4, that of nitrogen is 3. Likewise the following terms are to be construed: NH(Ci-C₄-alkyl), N(Ci-C₄-alkyl)₂, NH(C₃-C₆-cycloalkyl), N(C₃-C₆- cycloalkyl)₂, C(=0)OH, C(=0)-0-Ci-C₄-alkyl, C(=0)-NH(Ci-C₄-alkyl), C(=0)-N(Ci-C₄- alkyl)₂, C(=0)-NH(C₃-C₆-cycloalkyl), C(=0)-N(C₃-C₆-cycloalkyl)₂.

The term "saturated or partially unsaturated 3-, 4- 5-, 6- or 7-membered carbocycle" is to be understood as meaning both saturated or partially unsaturated carbocycles having 3, 4, 5, 6 or 7 ring members. Examples include cyclopropyl, cyclopentyl, cyclopentenyl, cyclopentadienyl, cyclohexyl, cyclohexenyl, cyclohexadienyl, cycloheptyl, cycloheptenyl, cycloheptadienyl, and the like.

The term "saturated or partially unsaturated 3-, 4-, 5-, 6-, or 7-membered heterocycle, wherein the ring member atoms of the heterocycle include besides carbon atoms 1 , 2, 3 or 4 heteroatoms independently selected from the group of N, O and S", is to be understood as meaning both saturated and partially unsaturated heterocycles, for example: a 3- or 4-membered saturated heterocycle which contains 1 or 2 heteroatoms from the group consisting of N, O and S as ring members such as oxirane, aziridine, thiirane, oxetane, azetidine, thiethane, [1 ,2]dioxetane, [1 ,2]dithietane, [1 ,2]diazetidine; and

a 5- or 6-membered saturated or partially unsaturated heterocycle which contains 1 , 2 or 3 heteroatoms from the group consisting of N, O and S as ring members such as 2-tetrahydrofuranyl, 3-tetrahydrofuranyl, 2-tetrahydrothienyl, 3- tetrahydrothienyl, 2-pyrrolidinyl, 3-pyrrolidinyl, 3-isoxazolidinyl, 4-isoxazolidinyl, 5- isoxazolidinyl, 3-isothiazolidinyl, 4-isothiazolidinyl, 5-isothiazolidinyl, 3- pyrazolidinyl, 4-pyrazolidinyl, 5-pyrazolidinyl, 2-oxazolidinyl, 4-oxazolidinyl, 5- oxazolidinyl, 2-thiazolidinyl, 4-thiazolidinyl, 5-thiazolidinyl, 2-imidazolidinyl, 4- imidazolidinyl, 1 ,2,4-oxadiazolidin-3-yl, 1 ,2,4-oxadiazolidin-5-yl, 1 ,2,4- thiadiazolidin-3-yl, 1 ,2,4-thiadiazolidin-5-yl, 1 ,2,4-triazolidin-3-yl, 1 ,3,4- oxadiazolidin-2-yl, 1 ,3,4-thiadiazolidin-2-yl, 1 ,3,4-triazolidin-2-yl, 2,3-dihydrofur-2- yl, 2,3-dihydrofur-3-yl, 2,4-dihydrofur-2-yl, 2,4-dihydrofur-3-yl, 2,3-dihydrothien-2- yl, 2,3-dihydrothien-3-yl, 2,4-dihydrothien-2-yl, 2,4-dihydrothien-3-yl, 2-pyrrolin-2- yl, 2-pyrrolin-3-yl, 3-pyrrolin-2-yl, 3-pyrrolin-3-yl, 2-isoxazolin-3-yl, 3-isoxazolin-3- yl, 4-isoxazolin-3-yl, 2-isoxazolin-4-yl, 3-isoxazolin-4-yl, 4-isoxazolin-4-yl,

2- isoxazolin-5-yl, 3-isoxazolin-5-yl, 4-isoxazolin-5-yl, 2-isothiazolin-3-yl,

3- isothiazolin-3-yl, 4-isothiazolin-3-yl, 2-isothiazolin-4-yl, 3-isothiazolin-4-yl, 4-isothiazolin-4-yl, 2-isothiazolin-5-yl, 3-isothiazolin-5-yl, 4-isothiazolin-5-yl, 2,3- dihydropyrazol-1 -yl, 2,3-dihydropyrazol-2-yl, 2,3-dihydropyrazol-3-yl, 2,3- dihydropyrazol-4-yl, 2,3-dihydropyrazol-5-yl, 3,4-dihydropyrazol-1 -yl, 3,4- dihydropyrazol-3-yl, 3,4-dihydropyrazol-4-yl, 3,4-dihydropyrazol-5-yl, 4,5- dihydropyrazol-1 -yl, 4,5-dihydropyrazol-3-yl, 4,5-dihydropyrazol-4-yl, 4,5- dihydropyrazol-5-yl, 2,3-dihydrooxazol-2-yl, 2,3-dihydrooxazol-3-yl, 2,3- dihydrooxazol-4-yl, 2,3-dihydrooxazol-5-yl, 3,4-dihydrooxazol-2-yl, 3,4- dihydrooxazol-3-yl, 3,4-dihydrooxazol-4-yl, 3,4-dihydrooxazol-5-yl, 3,4- dihydrooxazol-2-yl, 3,4-dihydrooxazol-3-yl, 3,4-dihydrooxazol-4-yl, 2-piperidinyl, 3-piperidinyl, 4-piperidinyl, 1 ,3-dioxan-5-yl, 2-tetrahydropyranyl, 4- tetrahydropyranyl, 2-tetrahydrothienyl, 3-hexahydropyridazinyl, 4-hexa- hydropyridazinyl, 2-hexahydropyrimidinyl, 4-hexahydropyrimidinyl, 5-hexahydro- pyrimidinyl, 2-piperazinyl, 1 ,3,5-hexahydrotriazin-2-yl and 1 ,2,4-hexahydrotriazin- 3-yl and also the corresponding -ylidene radicals; and

a 7-membered saturated or partially unsaturated heterocycle such as tetra- and hexahydroazepinyl, such as 2,3,4,5-tetrahydro[1 H]azepin-1 -,-2-,-3-,-4-,-5-,-6- or- 7-yl, 3,4,5,6-tetrahydro[2H]azepin-2-,-3-,-4-,-5-,-6- or-7-yl, 2,3,4,7- tetrahydro[1 H]azepin-1 -,-2-,-3-,-4-,-5-,-6- or-7-yl, 2,3,6,7-tetrahydro[1 H]azepin-1 - ,-2-, -3-, -4-, -5-, -6- or-7-yl, hexahydroazepin-1 -,-2-,-3- or-4-yl, tetra- and hexahydrooxepinyl such as 2,3,4,5-tetrahydro[1 H]oxepin-2-,-3-,-4-,-5-,-6- or-7-yl, 2,3,4,7-tetrahydro[1 H]oxepin-2-,-3-,-4-,-5-,-6- or-7-yl, 2,3,6,7- tetrahydro[1 H]oxepin-2-, -3-, -4-, -5-, -6- or-7-yl, hexahydroazepin-1 -,-2-,-3- or-4-yl, tetra- and hexahydro-1 ,3-diazepinyl, tetra- and hexahydro-1 ,4-diazepinyl, tetra- and hexahydro-1 ,3-oxazepinyl, tetra- and hexahydro-1 ,4-oxazepinyl, tetra- and hexahydro-1 ,3-dioxepinyl, tetra- and hexahydro-1 ,4-dioxepinyl and the corresponding -ylidene radicals; and

The term "5-or 6-membered heteroaryl" refers to aromatic ring systems incuding besides carbon atoms, 1 , 2, 3 or 4 heteroatoms independently selected from the group consisting of N, O and S, for example, a 5-membered heteroaryl such as pyrrol-1 -yl, pyrrol-2-yl, pyrrol-3-yl, thien-2-yl, thien-3-yl, furan-2-yl, furan-3-yl, pyrazol-1 -yl, pyrazol-3-yl, pyrazol-4-yl, pyrazol-5- yl, imidazol-1 -yl, imidazol-2-yl, imidazol-4-yl, imidazol-5-yl, oxazol-2-yl, oxazol-4- yl, oxazol-5-yl, isoxazol-3-yl, isoxazol-4-yl, isoxazol-5-yl, thiazol-2-yl, thiazol-4-yl, thiazol-5-yl, isothiazol-3-yl, isothiazol-4-yl, isothiazol-5-yl, 1 ,2,4-triazolyl-1 -yl, 1 ,2,4-triazol-3-yl 1 ,2,4-triazol-5-yl, 1 ,2,4-oxadiazol-3-yl, 1 ,2,4-oxadiazol-5-yl and 1 ,2,4-thiadiazol-3-yl, 1 ,2,4-thiadiazol-5-yl; or

a 6-membered heteroaryl, such as pyridin-2-yl, pyridin-3-yl, pyridin-4-yl, pyridazin-3-yl, pyridazin-4-yl, pyrimidin-2-yl, pyrimidin-4-yl, pyrimidin-5-yl, pyrazin-2-yl and 1 ,3,5-triazin-2-yl and 1 ,2,4-triazin-3-yl.

The inventive compounds I can be prepared by various routes in analogy to known processes described in the prior art, and, advantageously, by the synthesis shown in the following schemes and in the experimental part of this application.

Compounds of the formula I can be synthesized starting from known compounds II. They are accessible as shown in Scheme 1 and as described in DE 3406993 A1 , EP 321409 A2, DE 3430833 A1 , CN 101 125807: cheme 1 :

IV

Addition of HCN to ketone II, which is described in Tetrahedron Letters 2012, 53(15), 1978-1981 , Advanced Synthesis & Catalysis 2009, 351 (9), 1390-1394 or in

Tetrahedron Letters 1978, (40), 3773-3776, gives cyanohydrin of the formula III, which can be transformed to an intermediate ketone using a metal organic reagent (WO 200401 1410 A1 ; Journal of Organic Chemistry 1954, 19, 538-543; Synthesis 2001 , 10, 1487-1494). Further reaction with a metal organic compounds leads to tertiary alcohols of the formula IV, wherein R¹ and R² are not hydrogen, whereas reduction of the intermediate ketone leads to compounds IV wherein R² is hydrogen and R¹ is not hydrogen.

The alcohol IV may then be transformed by way of introduction of a leaving group LG, which is replaceable by a nucleophile, as shown in Scheme 2, for example by halogenation (LG meaning, for example, chlorine, bromine or iodine) or sulfonation (LG meaning, for example, methylsulfonate or tosylsulfonate) to provide compounds of formula V. The leaving group can then be replaced by an azole or imidazole residue upon treatment with triazole or imidazole in the presence of a base to yield compounds of the formula I wherein D is hydrogen.

Scheme 2:

v

Alternatively, compounds of the formula I can be prepared by transforming compound II into an epoxide of the formula VI with a suitable epoxidation method as outlined in Scheme 3 and described in WO 2010142779 A1 ; Organic Letters 2010, 12(4), 844- 846; Synthesis 2008, (9), 1404-1414; EP 29542 A2). Compounds VI can be reacted with triazole or imidazole in the presence of a base, which ultimately leads to compounds of the formula I wherein D is hydrogen.

Sch me 3:

Compounds of the formula I wherein D is SH or halogen can be prepared starting from compounds I wherein D is hydrogen upon reaction with a base, for example butyl lithium, lithium diisopropylamide, lithium hexamethyldisilazide, potassium

hexamethyldisilazide, lithium 2,2,6,6-tertramethylpiperidide or zink 2,2,6,6- tertramethylpiperidide, at low temperature in a suitable solvent such as Et.20, MTBE or THF, followed by addition of a suitable electrophile, for example Ss, CH3-S-S-CH3, , ICI, C2F₄Br2, to obtain correspondingly substituted azole compounds as has been described in Tetrahedron Letters 201 1 , 52(36), 4590-4594; WO 2006/102194 A1 , Journal of Organic Chemistry 2009, 74(21 ), 8309-8313; WO 201 1/1 13820 A1 ; WO 2012/025506 A1 , WO 9616048 A1 or in Synthesis 1999, 1 , 100-106.

Compounds I wherein D is SCN can be obtained by treating a compound I wherei D is SH with cyanogen halide such as Br-CN or CI-CN and a base (organic or inorganic base such as K2CO3, NaOH, KOH or NEt.3, DBU) in a suitable solvent such as acetone, MeCN or THF in analogy to methods reported in: WO 2009/077497 A2 or in Chemical & Pharmaceutical Bulletin 1964, 12(2), 182-191 . Compounds I wherein D is SH can be functionalized at the sulfur atom using standard procedures, for example with an alkylation agent such as metyl iodide in the presence of a base (organic or inorganic base such as K2CO3, NaOH, KOH or NEt.3, DBU) in a suitable solvent such as acetone, MeCN or THF. These compounds can be synthesized for example in analogy with reported methods in: WO 2012/047762 A2, Heteroatom Chemistry 2010, 20(7), 405- 410, Khimiya Geterotsiklicheskikh Soedinenii 1977, (1 1 ), 1561 -1563, Indian Journal of Heterocyclic Chemistry 1999, 8(4), 341 -342 or in WO 201 1/1 13820 A1 .

Compounds of the formula I wherein X is OR³ can be obtained from the reaction of compound I wherein X is OH in the presence of an electrophile (e.g. Mel, ethyl bromide, cyclopropyl bromide, 1 ,4-dibromobutane, propargyl bromide, methyl chloroformate, allyl bromide, acetylene, cyclohexene, cyclopentene, phenol) and a base (e.g. NaH, KH, f-BuOK, NaH, KOH, Et₃N, LDA, imidazole, K₂C0₃, Cs₂C0₃) and in an inert organic solvent preferably (e.g. THF, DME, Et₂0, DMF, NMP, DMSO, toluene, acetonitrile). These compounds can be synthesized in analogy with the procedures described in: Chemische Berichte 1986, 1 19(12), 3672-3693; Journal of Organic Chemistry 201 1 , 76(14), 5825-5831 ; Synlett 2001 , 1962-1964; Tetrahedron 1987, 43(10), 231 1 -2316; Organometallics 2003, 22(19), 3915-3920; Tetrahedron 2007, 63(37), 9071 -9081 ; Tetrahedron 2007, 63(37), 9071 -9081 or in Journal of Organometallic Chemistry 1987, 334(1 -2), 225-242. Compounds of the formula I wherein X is CN can be synthesized from compounds I wherein X is OH by transformation of the OH group into a leaving group as described above for compounds V followed by substitution with an appropriate cyanide source (Organic Process Research & Development 2012, 16(8), 1385-1392; WO 2012024150 A1 ; US 20100056637 A1 ; Organic Letters 2008, 10(20), 4573-4576). Such nitriles can also be obtained from compounds I wherein X is OH in presence of a reagent, for example cyanuric trichloride, NaCN, tetrabutylammonium cyanide and/or an additive (for example N-tosylimidazole, Bu₄NI, Bu₄NCI, Bu₄NBr, TMSCI, DDQ, PPh₃) in an inert organic solvent (for example THF, DME, Et20, DMF, NMP, DMSO, toluene, acetonitrile). These compounds can be prepared for example in analogy to methods described in: Letters in Organic Chemistry 2005, 2(8), 725-730, Tetrahedron Letters 2007, 48(38), 6779-6784, Journal of Organic Chemistry 2004, 69(7), 2562-2564 or in Organic Chemistry: An Indian Journal 2008, 4(1 ), 32-35.

Compounds II can be prepared from carboxyclic acid chlorides and Grignard reagents as shown in Scheme 4. Reaction of a suitably substituted halobenzene compound A, wherein Hal stands for halogen, for example chlorine, bromine or iodine, with trans- metallation reagents such as isopropylmagnesium halides and subsequent reaction with a carboxyclic acid chloride, preferably under anhydrous conditions, and optionally in the presence of a catalyst such as CuCI, AICI₃, LiCI and mixtures thereof, provides acetophenones of the formula II.

Scheme 4:

A

II

If individual compounds I cannot be obtained by the routes described above, they can be prepared by derivatization of other compounds I. The N-oxides may be prepared from the compounds I according to conventional oxidation methods, e. g. by treating compounds I with an organic peracid such as metachloroperbenzoic acid (cf. WO 03/64572 or J. Med. Chem. (1995), 38(1 1 ), 1892-1903,); or with inorganic oxidizing agents such as hydrogen peroxide (cf. J. Heterocyc. Chem. (1981 ), 18 (7), 1305-1308) or oxone (cf. J. Am. Chem. Soc. (2001 ), 123 (25), 5962-5973). The oxidation may lead to pure mono-N-oxides or to a mixture of different N-oxides, which can be separated by conventional methods such as chromatography.

If the synthesis yields mixtures of isomers, a separation is generally not necessarily required since in some cases the individual isomers can be interconverted during work- up for use or during application (e. g. under the action of light, acids or bases). Such conversions may also take place after use, e. g. in the treatment of plants in the treated plant, or in the harmful fungus to be controlled.

The reaction mixtures are worked up in a customary manner, for example by mixing with water, separating the phases and, if appropriate, chromatic purification of the crude products. In some cases, the intermediates and end products are obtained in the form of colorless or slightly viscous oils which can be freed from volatile components or purified under reduced pressure and at moderately elevated temperatures. If the intermediates and end products are obtained as solids, purification can also be carried out by recrystallization or digestion.

Agriculturally useful salts of the compounds I encompass especially the salts of those cations or the acid addition salts of those acids whose cations and anions, respectively, have no adverse effect on the fungicidal action of the compounds I. Suitable cations are thus in particular the ions of the alkali metals, preferably sodium and potassium, of the alkaline earth metals, preferably calcium, magnesium and barium, of the transition metals, preferably manganese, copper, zinc and iron, and also the ammonium ion which, if desired, may carry one to four Ci-C4-alkyl substituents and/or one phenyl or benzyl substituent, preferably diisopropylammonium, tetramethylammonium, tetrabutylammonium, trimethylbenzylammonium, furthermore phosphonium ions, sulfonium ions, preferably tri(Ci-C4-alkyl)sulfonium, and sulfoxonium ions, preferably tri(Ci-C4-alkyl)sulfoxonium.

Anions of useful acid addition salts are primarily chloride, bromide, fluoride,

hydrogensulfate, sulfate, dihydrogenphosphate, hydrogenphosphate, phosphate, nitrate, bicarbonate, carbonate, hexafluorosilicate, hexafluorophosphate, benzoate, and the anions of Ci-C4-alkanoic acids, preferably formate, acetate, propionate and butyrate. They can be formed by reacting a compound I with an acid of the

corresponding anion, preferably of hydrochloric acid, hydrobromic acid, sulfuric acid, phosphoric acid or nitric acid.

In one aspect the invention relates to intermediates of formula IV. In a further aspect the invention relates to intermediates of formula V. In still another aspect the invention relates to intermediates of formula VI. In the following, the meaning of the substituents of the compounds used according to the invention is further defined. Thereby, in each case the substituents are meant to have the given meanings and preferred meaning on their own or in any combination with the meanings or preferred meanings of any other substituent. The groups mentioned herein in tables A and B, as well as in tables 1 to 1288, for a combination of substituents are furthermore, independently of the combination in which they are mentioned, particularly preferred embodiments of the substituent or of the combination of substituents in question.

A according to the invention is N or CH. According to one embodiment A is N.

According to a further embodiment A is CH.

D according to the present invention is hydrogen, halogen or SR^D, wherein R^D is hydrogen, CN, d-Ce-alkyl, d-Ce-haloalkyl, C2-Ce-alkenyl, C2-Ce-haloalkenyl, C2-C6- alkynyl or C2-C6-haloalkynyl.

In a preferred embodiment D is hydrogen, halogen, SH , SCN or S-CH2-CH=CH2 (S-allyl). According to one embodiment D is hydrogen. According to a further embodiment, D is halogen, in particular iodine. According to another preferred embodiment D is SR^D. According to a particular embodiment, R^D is H. In yet another preferred embodiment R^D is CN. In a further preferred embodiment R^D is

-CH₂-CH=CH₂.

R¹ according to the invention is halogen, CN, NO2, OH, SH , Ci-C6-alkyl, Ci-C6-alkoxy, Ci-C6-alkylthio, Ci-C6-alkylsulfinyl, Ci-C6-alkylsulfonyl, C2-C6-alkenyl, C2-C6-alkynyl, C₃- Ce-cycloalkyl, C₃-C₈-cycloalkyloxy, C₃-C₈-cycloalkyl-Ci-C₄-alkyl, NH₂, NH(Ci-C₄-alkyl), N(Ci-C₄-alkyl)₂, N H(C₃-C₆-cycloalkyl), N(C₃-C₆-cycloalkyl)₂, C(=0)-Ci-C₄-alkyl,

C(=0)OH, C(=0)-0-Ci-C₄-alkyl, C(=0)-NH(Ci-C₄-alkyl), C(=0)-N(Ci-C₄-alkyl)₂, C(=0)-NH(C₃-C₆-cycloalkyl), C(=0)-N(C₃-C₆-cycloalkyl)₂, phenyl, heteroaryl, phenyl- Ci-C₄-alkyl or heteroaryl-Ci-C₄-alkyl, wherein the heteroaryl radical in the last- mentioned groups is 5- or 6-membered; and wherein the aliphatic, alicyclic and aromatic moieties of R¹ are unsubstituted or substituted by one, two, three or four or up to the maximum possible number of independently selected substituents R^1a; wherein R^1a is halogen, CN, N0₂, OH, SH, NH₂, Ci-C₆-alkyl, Ci-C₆-haloalkyl, Ci-C₆-alkoxy, Ci-C6-haloalkoxy, Ci-C6-alkylthio, Ci-C6-haloalkylthio, C₃-C8-cycloalkyl or Ci-C₄-alkoxy- Ci-C₄-alkyl.

R² according to the invention is hydrogen, halogen, CN, NO2, OH, SH , Ci-C6-alkyl, Ci-C6-alkoxy, Ci-C6-alkylthio, Ci-C6-alkylsulfinyl, Ci-C6-alkylsulfonyl, C2-C6-alkenyl, C2-Ce-alkynyl, C₃-C8-cycloalkyl, C₃-C8-cycloalkyloxy, C₃-C8-cycloalkyl-Ci-C₄-alkyl, NH₂, NH(Ci-C₄-alkyl), N(Ci-C₄-alkyl)₂, N H(C₃-C₆-cycloalkyl), N(C₃-C₆-cycloalkyl)₂,

C(=0)-Ci-C₄-alkyl, C(=0)OH, C(=0)-0-Ci-C₄-alkyl, C(=0)-NH(Ci-C₄-alkyl),

C(=0)-N(Ci-C₄-alkyl)₂, C(=0)-NH(C₃-C₆-cycloalkyl), C(=0)-N(C₃-C₆-cycloalkyl)₂, phenyl, heteroaryl, phenyl-Ci-C4-alkyl or heteroaryl-Ci-C4-alkyl, wherein the heteroaryl group in the last-mentioned groups is 5- or 6-membered; and wherein the aliphatic, alicyclic and aromatic moieties of R² are unsubstituted or substituted by one, two, three or four or up to the maximum possible number of independently selected substituents R^2a; wherein R^2a is halogen, CN, N0₂, OH, SH, NH₂, Ci-C₆-alkyl, Ci-C₆-haloalkyl, d-C₆-alkoxy,

Ci-C6-haloalkoxy, Ci-C6-alkylthio, Ci-C6-haloalkylthio, Cs-Cs-cycloalkyl or d-d-alkoxy- Ci-C₄-alkyl.

According to a preferred embodiment of the invention R² is hydrogen, halogen, CN, N0₂, OH , SH, Ci-Ce-alkyl, Ci-C₆-alkoxy, Ci-C₆-alkylthio, Ci-C₆-alkylsulfinyl, Ci-C₆- alkylsulfonyl, C2-C6-alkenyl, C2-C6-alkynyl, Cs-Cs-cycloalkyl, Cs-Cs-cycloalkyloxy, C₃-Cs- cycloalkyl-Ci-C₄-alkyl, NH₂, NH(Ci-C₄-alkyl), N(Ci-C₄-alkyl)₂, N H(C₃-C₆-cycloalkyl), N(C₃-C₆-cycloalkyl)₂, C(=0)-Ci-C₄-alkyl, C(=0)OH, C(=0)-0-Ci-C₄-alkyl,

C(=0)-NH(Ci-C₄-alkyl), C(=0)-N(Ci-C₄-alkyl)₂, C(=0)-NH(C₃-C₆-cycloalkyl), C(=0)- N(C3-C6-cycloalkyl)₂, phenyl, heteroaryl, phenyl-Ci-C4-alkyl or heteroaryl-Ci-C4-alkyl, wherein the heteroaryl radical in the last-mentioned groups is 5- or 6-membered; and wherein the aliphatic, alicyclic and aromatic moieties of R² are unsubstituted or substituted by one, two, three or four or up to the maximum possible number of independently selected substituents R^2a; wherein R^2a is halogen, CN, N0₂, OH, SH, NH₂, Ci-Ce-alkyl, Ci-C₆-haloalkyl, Ci-C₆-alkoxy, Ci-C₆-haloalkoxy, Ci-C₆-alkylthio, Ci-C6-haloalkylthio, Cs-Cs-cycloalkyl or Ci-C4-alkoxy-Ci-C4-alkyl.

According to another preferred embodiment of the invention R² is halogen, CN, N0₂, OH, SH, Ci-Ce-alkyl, Ci-C₆-alkoxy, Ci-C₆-alkylthio, Ci-C₆-alkylsulfinyl, Ci-C₆- alkylsulfonyl, C₂-C6-alkenyl, C₂-C6-alkynyl, Cs-Cs-cycloalkyl, Cs-Cs-cycloalkyloxy, C₃-Cs- cycloalkyl-Ci-C₄-alkyl, NH₂, NH(Ci-C₄-alkyl), N(Ci-C₄-alkyl)₂, N H(C₃-C₆-cycloalkyl), N(C₃-C₆-cycloalkyl)₂, C(=0)-Ci-C₄-alkyl, C(=0)OH, C(=0)-0-Ci-C₄-alkyl, C(=0)-

NH(Ci-C₄-alkyl), C(=0)-N(Ci-C₄-alkyl)₂, C(=0)-NH(C₃-C₆-cycloalkyl), C(=0)-N(C₃-C₆- cycloalkyl)₂, phenyl, heteroaryl, phenyl-Ci-C4-alkyl or heteroaryl-Ci-C4-alkyl, wherein the heteroaryl radical in the last-mentioned groups is 5- or 6-membered; and wherein the aliphatic, alicyclic and aromatic moieties of R² are unsubstituted or substituted by one, two, three or four or up to the maximum possible number of independently selected substituents R^2a; wherein R^2a is halogen, CN, N0₂, OH, SH, NH₂, Ci-Ce-alkyl, Ci-C6-haloalkyl, Ci-C6-alkoxy, Ci-C6-haloalkoxy, Ci-C6-alkylthio, Ci-C6-haloalkylthio, C3-Cs-cycloalkyl or Ci-C4-alkoxy-Ci-C4-alkyl.

According to a further preferred embodiment R² is hydrogen, halogen, CN, N0₂, OH, SH, Ci-C6-alkyl, Ci-C6-hydroxyalkyl, Ci-C6-haloalkyl, Ci-C6-alkoxy, Ci-C6-haloalkoxy, d-Ce-alkylthio, Ci-Ce-haloalkylthio, Ci-C₄-alkoxy-Ci-C₄-alkyl, C₂-C₆-alkenyl, C₂-C₆- alkynyl, C₂-C6-haloalkenyl, d-drhaloalkynyl, Cs-Cs-cycloalkyl, Cs-Cs-cycloalkyloxy, C₃-Cs-cycloalkyl-Ci-C4-alkyl, NH₂, NH(Ci-C₄-alkyl) or N(Ci-C₄-alkyl)₂. Preferably, R² is halogen, CN, N0₂, OH, NH₂, N(CH₃)₂, Ci-Ce-alkyl, Ci-C₆-haloalkyl, Ci-C₆-alkoxy, d-Ce-haloalkoxy, Ci-Ce-alkylthio, Ci-Ce-haloalkylthio, Ci-C4-alkoxy-Ci-C₄-alkyl, C₂-C6-alkenyl, C₂-C6-alkynyl or Cs-Cs-cycloalkyl.

According to another preferred embodiment R² is halogen, CN , N0₂, OH, SH, Ci-Ce- alkyl, Ci-C6-hydroxyalkyl, Ci-drhaloalkyl, Ci-C6-alkoxy, Ci-C6-haloalkoxy, C1-C6- alkylthio, Ci-C6-haloalkylthio, Ci-C4-alkoxy-Ci-C4-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C2-C6-haloalkenyl, C2-C6-haloalkynyl, Cs-Cs-cycloalkyl, Cs-Cs-cycloalkyloxy, C3-C8- cycloalkyl-Ci-C₄-alkyl, NH₂, NH(Ci-C₄-alkyl) or N(Ci-C₄-alkyl)₂. Preferably, R² is halogen, CN, N0₂, OH, NH₂, N(CH₃)₂, Ci-C₆-alkyl, Ci-C₆-haloalkyl, Ci-C₆-alkoxy,

Ci-C6-haloalkoxy, Ci-C6-alkylthio, Ci-C6-haloalkylthio, Ci-C₄-alkoxy-Ci-C₄-alkyl, C2-C6-alkenyl, C2-C6-alkynyl or Cs-Cs-cycloalkyl.

In still a further preferred embodiment R² is hydrogen, halogen, CN, OH, NH2, N(CHs)2, Ci-C6-alkyl, Ci-C6-haloalkyl, Ci-C6-alkoxy, Ci-C6-haloalkoxy, C2-C6-alkenyl, C2-C6- alkynyl or Cs-Cs-cycloalkyl.

In yet another preferred embodiment R² is halogen, CN, OH, NH2, N(CHs)2, Ci-C6-alkyl, Ci-C6-haloalkyl, Ci-C6-alkoxy, Ci-C6-haloalkoxy, C2-C6-alkenyl, C2-C6-alkynyl or Cs-Cs- cycloalkyl.

In another preferred embodiment R² is hydrogen, halogen, CN, OH, NH2, N(CHs)2, Ci-C6-alkyl, Ci-C6-alkoxy, C2-C6-alkenyl, C2-C6-alkynyl and Cs-Cs-cycloalkyl.

In still another preferred embodiment R² is halogen, CN, OH, NH2, N(CHs)2, Ci-C6-alkyl, Ci-C6-alkoxy, C2-C6-alkenyl, C2-C6-alkynyl and Cs-Cs-cycloalkyl.

According to a further preferred embodiment of the invention, R² is Cs-Cs-cycloalkyl, phenyl or 5- or 6-membered heteroaryl, wherein the alicyclic and aromatic moieties of R² are unsubstituted or substituted by one, two, three or four or up to the maximum possible number of independently selected substituents R^2a. In another preferred embodiment R² is Cs-Cs-cycloalkyl, in particular cyclopropyl.

According to a further preferred embodiment of the invention, R² is phenyl or 5- or 6- membered heteroaryl, wherein the aromatic moieties of R² is unsubstituted or substituted by one, two, three or four or up to the maximum possible number of independently selected substituents R^2a.

In another preferred embodiment R² is C2-C6-alkenyl, in particular 2-propenyl, or C2-C6- alkynyl, in particular 2-propynyl and 2-butynyl.

In one further preferred aspect of the invention R² is Ci-C6-haloalkyl, in particular CF3 or CHF2, or Ci-C6-haloalkoxy, in particular OCF3 or OCHF2.

In a preferred embodiment R² is halogen, in particular chlorine or bromine.

According to a further preferred embodiment R² is Ci-C6-alkyl, in particular Ci-C₄-alkyl, more particularly methyl, ethyl and 1 -methylethyl.

Furthermore, in a preferred embodiment R² is Ci-C6-alkoxy, in particular methoxy, ethoxy or 1 -methylethoxy.

In another preferred embodiment R² is C2-C6-alkenyl, in particular 2-propenyl, or C2-C6- alkynyl, in particular 2-propynyl and 2-butynyl. In one further aspect of the invention R² is Ci-C6-haloalkyl, in particular CF3 or CHF2, or Ci-C6-haloalkoxy, in particular OCF3 or OCHF2. In another preferred embodiment R² is hydrogen. According to one embodiment of the invention R¹ is halogen, CN, NO2, OH, SH, C1-C6- alkyl, Ci-C6-alkoxy, Ci-C6-alkylthio, Ci-C6-alkylsulfinyl, Ci-C6-alkylsulfonyl, C2-C6-alk- enyl, C2-C6-alkynyl, Cs-Cs-cycloalkyl, Cs-Cs-cycloalkyloxy, C3-Cs-cycloalkyl-Ci-C₄-alkyl, NH₂, NH(Ci-C₄-alkyl), N(Ci-C₄-alkyl)₂, NH(C₃-C₆-cycloalkyl), N(C₃-C₆-cycloalkyl)2, C(=0)-Ci-C₄-alkyl, C(=0)OH, C(=0)-0-Ci-C₄-alkyl, C(=0)-NH(Ci-C₄-alkyl),

C(=0)-NH(C₃-C₆-cycloalkyl), C(=0)-N(C₃-C₆-cycloalkyl)₂, phenyl, heteroaryl, phenyl-Ci-C₄-alkyl or heteroaryl-Ci-C4-alkyl, wherein the heteroaryl radical in the last-mentioned groups is 5- or 6-membered; and wherein the aliphatic, alicyclic and aromatic moieties of R¹ are unsubstituted or substituted by one, two, three or four or up to the maximum possible number of independently selected substituents R^1a; wherein R^1a is halogen, CN, N0₂, OH, SH, NH₂, Ci-C₆-alkyl, Ci-C₆-haloalkyl, d-C₆-alk- oxy, Ci-C6-haloalkoxy, Ci-C6-alkylthio, Ci-C6-haloalkylthio, Cs-Cs-cycloalkyl or Ci-C₄- alkoxy-Ci-C₄-alkyl and R² is independently as defined or preferably defined above. According to another embodiment R¹ is halogen, CN, N0₂, OH, SH, Ci-C6-alkyl, C1-C6- hydroxyalkyl, Ci-C6-haloalkyl, Ci-C6-alkoxy, Ci-C6-haloalkoxy, Ci-C6-alkylthio, C1-C6- haloalkylthio, Ci-C₄-alkoxy-Ci-C₄-alkyl, C₂-C6-alkenyl, C₂-C6-alkynyl, C₂-C6-haloalkenyl, C₂-C6-haloalkynyl, Cs-Cs-cycloalkyl, C3-Cs-cycloalkyloxy, C3-C8-cycloalkyl-Ci-C₄-alkyl, NH₂, NH(Ci-C₄-alkyl) or N(Ci-C₄-alkyl)₂ and R² is independently as defined for R¹ or hydrogen. Preferably, R¹ is halogen, CN, N0₂, OH, NH₂, N(CH₃)₂, Ci-C₆-alkyl, Ci-C₆- haloalkyl, Ci-C6-alkoxy, Ci-C6-haloalkoxy, Ci-C6-alkylthio, Ci-C6-haloalkylthio, Ci-C₄- alkoxy-Ci-C₄-alkyl, C₂-C6-alkenyl, C₂-C6-alkynyl or Cs-Cs-cycloalkyl and R² is as defined or preferably defined above. In a further preferred embodiment R¹ is halogen, CN, OH, NH₂, N(CHs)₂, d-Ce-alkyl, Ci-C₆-haloalkyl, Ci-C₆-alkoxy, Ci-C₆-haloalkoxy, C₂-C₆-alk- enyl, C₂-C6-alkynyl or Cs-Cs-cycloalkyl and R² is independently as defined or preferably defined above.

In still another preferred embodiment R¹ is halogen, CN, OH, NH₂, N(CHs)₂, Ci-C6-alkyl, Ci-C6-alkoxy, C₂-C6-alkenyl, C₂-C6-alkynyl and Cs-Cs-cycloalkyl and R² is

independently as defined or preferably defined above.

In one preferred embodiment R¹ is halogen, CN, N0₂, OH, NH₂, N(CHs)₂, Ci-C6-alkyl, Ci-C6-haloalkyl, Ci-C6-alkoxy, Ci-C6-haloalkoxy, Ci-C6-alkylthio, Ci-C6-haloalkylthio, Ci-C₄-alkoxy-Ci-C₄-alkyl, C₂-C6-alkenyl C₂-C6-alkynyl or Cs-Cs-cycloalkyl, and wherein R² is hydrogen or a radical as defined for R¹. In one aspect of the invention R¹ is CN and R² is as defined or preferably defined above. In a further aspect R¹ is CN and R² is CN. In yet another aspect R¹ is CN and R² is hydrogen.

In a further specific aspect of the invention R¹ is OH, SH or NH₂ and R² is as defined or preferably defined above. In still another specific aspect R² is hydrogen and R¹ is OH, SH or NH₂. In a further aspect R² is hydrogen and R¹ is OH, SH or NH₂.

In one preferred embodiment R¹ is C₂-C6-alkenyl, in particular 2-propenyl, or C₂-C6- alkynyl, in particular 2-propynyl and 2-butynyl and R² is as defined or preferably defined above. In a preferred embodiment R² is hydrogen and R¹ is C₂-C6-alkenyl, in particular 2-propenyl, or C₂-C6-alkynyl, in particular 2-propynyl and 2-butynyl.

In another preferred embodiment R¹ is Ci-C6-haloalkyl, in particular CF3 or CHF₂, or Ci-C6-haloalkoxy and R² is as defined or preferably defined above. In one further aspect of the invention R² is hydrogen and R¹ is Ci-C6-haloalkyl, in particular CF3 or CHF₂, or Ci-C6-haloalkoxy, in particular OCF3 or OCHF₂. In a further preferred embodiment R¹ is Cs-Cs-cycloalkyl, phenyl or 5- or 6-membered heteroaryl, wherein the alicyclic and aromatic moieties of R¹ are unsubstituted or substituted by one, two, three or four or up to the maximum possible number of independently selected substituents R^1a and R² is as defined or preferably defined above. In still another preferred embodiment R² is hydrogen and R¹ is Cs-Cs-cycloalkyl, phenyl or 5- or 6-membered heteroaryl, wherein the alicyclic and aromatic moieties of R¹ are unsubstituted or substituted by one, two, three or four or up to the maximum possible number of independently selected substituents R^1a.

According to a further embodiment of the invention, R¹ is phenyl or 5- or 6-membered heteroaryl, wherein the aromatic moieties of R¹ are unsubstituted or substituted by one, two, three or four or up to the maximum possible number of independently selected substituents R^1a and R² is independently as defined or preferably defined above.

According to yet another embodiment of the invention R² is hydrogen and R¹ is phenyl or 5- or 6-membered heteroaryl, wherein the aromatic moieties of R¹ are unsubstituted or substituted by one, two, three or four or up to the maximum possible number of independently selected substituents R^1a.

In another preferred embodiment R¹ is Cs-Cs-cycloalkyl, in particular cyclopropyl and R² is as defined or preferably defined above. In still a further preferred embodiment R² is hydrogen and R¹ is Cs-Cs-cycloalkyl, in particular cyclopropyl.

According to one embodiment of the invention R¹ and R² together with the carbon atom to which they are bound (denominated as C^*) form a vinyl group C^*=CR¹¹R²², wherein R¹¹ and R²² are as defined or preferably defined below; or R¹ and R² together with the carbon atom to which they are bound form a saturated or partially unsaturated three-, four-, five-, six- or seven-membered carbocycle or a saturated or partially unsaturated three-, four-, five-, six- or seven-membered heterocycle, wherein the heterocycle includes beside carbon atoms one, two, three or four heteroatoms independently selected from the group consisting of N, O and S, and wherein the carbo- and heterocycle are unsubstituted or carry one, two, three or four independently selected substituents R¹² as defined and preferably defined below, and wherein one or two Chb groups of the carbo- or heterocycle may be replaced by one or two groups

independently selected from the group of C(=0) and C(=S).

According to a further embodiment of the invention R¹ and R² together with the carbon atom to which they are bound (denominated as C^*) form a vinyl group C^*=CR¹¹R²², wherein R¹¹ and R²² are as defined or preferably defined below; or R¹ and R² together with the carbon atom to which they are bound form a saturated or partially unsaturated three-, four-, five-, six- or seven-membered carbocycle, which is unsubstituted or carries one, two, three or four independently selected substituents R¹² as defined and preferably defined below, and wherein one or two Chb groups of the carbocycle may be replaced by one or two groups independently selected from the group of C(=0) and C(=S). According to a further embodiment of the invention R¹ and R² together with the carbon atom to which they are bound (denominated as C^*) form a vinyl group C^*=CR¹¹R²², wherein R¹¹ and R²² are as defined or preferably defined below. R¹¹ and R²² according to the invention are independently selected from the group consisting of hydrogen, halogen, CN, NO2, OH, SH, NH2, Ci-C6-alkyl, Ci-C6-haloalkyl, Ci-C6-alkoxy, Ci-C6-haloalkoxy, Ci-C6-alkylthio, Ci-C6-haloalkylthio and Ci-C4-alkoxy- Ci-C4-alkyl. In another preferred embodiment R¹ and R² are independently selected from the group consisting of hydrogen, halogen and Ci-C6-alkyl. In a further preferred embodiment R¹¹ and R²² are hydrogen

In a further embodiment of the invention R¹ and R² together with the carbon atom to which they are bound form a saturated or partially unsaturated three-, four-, five-, six- or seven-membered carbocycle or a saturated or partially unsaturated three-, four-, five-, six- or seven-membered heterocycle, wherein the heterocycle includes beside carbon atoms one, two, three or four heteroatoms independently selected from the group consisting of N, O and S, and wherein the carbo- and heterocycle are unsubstituted or carry one, two, three or four independently selected substituents R¹² as defined and preferably defined below, wherein one or two CH2 groups of the carbo- or heterocycle may be replaced by one or two groups independently selected from the group of C(=0) and C(=S), such as in, for example, cyclopropanone, cyclopentanone, cyclopropanethione, cyclopentanethione, 5-oxazolone, cyclohexane-1 ,4-dione, cyclohexane-1 ,4-dithione. According to another embodiment of the invention R¹ and R² together with the carbon atom to which they are bound form a saturated or partially unsaturated three-, four-, five-, six- or seven-membered carbocycle which is unsubstituted or carries one, two, three or four independently selected substituents R¹² as defined and preferably defined below.

In one preferred embodiment R¹ and R² together with the carbon atom to which they are bound form a saturated carbocycle, in particular selected from the group consisting of cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl and cycloheptyl, wherein the carbocycle in each case is unsubstituted or carries one, two, three or four

independently selected substituents R¹² as defined and preferably defined below. In another preferred embodiment R¹ and R² together with the carbon atom to which they are bound form a partially unsaturated carbocycle, in particular selected from the group consisting of cyclopentenyl, cyclopentadienyl and cyclohexenyl and wherein the carbocycle is unsubstituted or carries one, two, three or four independently selected substituents R¹² as defined and preferably defined below.

In a specific embodiment thereof, R¹ and R² together with the carbon atom to which they are bound form a cyclopropyl ring which is unsubstituted or carries one, two, three or four independently selected substituents R¹² as defined and preferably defined below. According to a further specific embodiment R¹ and R² together with the carbon atom to which they are bound form a cyclobutyl ring which is unsubstituted or carries one, two, three or four independently selected substituents R¹² as defined and preferably defined below.

In still a further specific embodiment of the invention R¹ and R² together with the carbon atom to which they are bound form a cyclopentyl ring which is unsubstituted or carries one, two, three or four independently selected substituents R¹² as defined and preferably defined below.

In yet another preferred embodiment R¹ and R² together with the carbon atom to which they are bound form a cyclohexyl ring which is unsubstituted or carries one, two, three or four independently selected substituents R¹² as defined and preferably defined below.

According to still another embodiment of the invention R¹ and R² together with the carbon atom to which they are bound form a saturated or partially unsaturated three-, four-, five-, six- or seven-membered heterocycle, in particular a three-, four- or five- membered heterocycle, wherein the heterocycle includes beside carbon atoms one, two, three or four, in particular one or two, heteroatoms independently selected from the group consisting of N, O and S, and wherein the heterocycle is unsubstituted or carries one, two, three or four independently selected substituents R¹² as defined and preferably defined below.

In one specific embodiment thereof R¹ and R² form a heterocycle selected from the group consisting of oxirane, aziridine, thiirane, oxetane, azetidine, thiethane, 2- tetrahydrofuranyl, 3-tetrahydrofuranyl, 2-tetrahydrothienyl and 3-tetrahydrothienyl, wherein the heterocycle is unsubstituted or carries one, two, three or four

independently selected substituents R¹² as defined and preferably defined below. In a further specific embodiment R¹ and R² together with the carbon atom to which they are bound form an oxirane which is unsubstituted or carries one, two, three or four independently selected substituents R¹² as defined and preferably defined below. In still a further specific embodiment of the invention R¹ and R² together with the carbon atom to which they are bound form an oxetane which is unsubstituted or carries one, two, three or four independently selected substituents R¹² as defined and preferably defined below. R¹² according to the invention is in each case independently selected from the group consisting of halogen, CN , N0₂, OH , SH , N H₂, Ci-C₆-alkyl, d-C₆-haloalkyl,

Ci-C6-alkoxy, Ci-C6-haloalkoxy, Ci-C6-alkylthio, Ci-C6-haloalkylthio, Ci-C₄-alkoxy- Ci-C4-alkyl, phenyl or phenoxy; wherein the phenyl moieties of R¹² are unsubstituted or substituted by one, two, three or four independently selected substituents R^12a; wherein R^12a is halogen, CN , N0₂, OH , SH , N H₂, Ci-C₆-alkyl, Ci-C₆-haloalkyl, Ci-C₆-alkoxy,

Ci-C6-haloalkoxy, Ci-C6-alkylthio, Ci-C6-haloalkylthio, Cs-Cs-cycloalkyl or Ci-C₄-alkoxy- Ci-C₄-alkyl. In a preferred embodiment R¹² is halogen, CN , NO2, OH , SH , N H2, Ci-C6-alkyl, Ci-C6-haloalkyl, Ci-C6-alkoxy, Ci-C6-haloalkoxy, Ci-C6-alkylthio, Ci-C6-haloalkylthio or C 1 -C₄-a I koxy-C 1 -C₄-a I ky I .

In another preferred embodiment R¹² is halogen, CN , Ci-C6-alkyl, Ci-C6-haloalkyl, Ci-C6-alkoxy or Ci-C6-haloalkoxy. In another preferred embodiment R¹² is halogen, CN or Ci-C6-alkyl. In yet another preferred embodiment R¹² is halogen, in particular fluorine. In a further preferred embodiment R¹² is chlorine. In still another preferred aspect of the invention R¹² is Ci-C6-alkyl, in particular Ci-C₄-alkyl, even more preferably methyl.

X according to the invention is OR³ or CN . In one embodiment X is CN . According to another embodiment X is OR³, wherein R³ is hydrogen, Ci-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C2-C6-alkynyl, Cs-Cs-cycloalkyl, Ci-C6-alkylsulfonyl, phenylsulfonyl,

C(=0)-N H(Ci-C₄-alkyl),

C(=0)-Ci-C₄-alkylphenyl, phenyl, phenyl-Ci-C₄-alkyl, phenyl-C2-C₄-alkenyl or phenyl-C2-C₄-alkynyl; wherein the aliphatic, alicyclic and aromatic moieties of R³ are unsubstituted or substituted by one, two, three or four or up to the maximum possible number of independently selected substituents R^3a as defined or preferably defined below.

According to one specific embodiment thereof, R³ is hydrogen.

According to a further embodiment R³ is hydrogen Ci-C6-alkyl, Ci-C6-hydroxyalkyl, Ci-C6-haloalkyl, Ci-C₄-alkoxy-Ci-C₄-alkyl, C2-C6-alkenyl, C2-C6-alkynyl,

C2-C6-haloalkenyl, C2-C6-haloalkynyl, Cs-Cs-cycloalkyl, C3-Cs-cycloalkyl-Ci-C₄-alkyl, d-Ce-alkylsulfonyl, phenylsulfonyl,

C(=0)-N H(Ci-C₄-alkyl),

phenyl, phenyl-Ci-C₄-alkyl, phenyl-C2-C₄-alkenyl or phenyl-C2-C₄-alkynyl; wherein the aliphatic, alicyclic and aromatic moieties of R³ in each case either do not carry any further substituents or in each case may further carry one, two, three or up to the maximum possible number of independently selected substituents R^3a as defined or preferably defined below.

In another embodiment of the invention R³ is hydrogen, Ci-C6-alkyl, C1-C6- hydroxyalkyl, Ci-C6-haloalkyl, Ci-C₄-alkoxy-Ci-C₄-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C2-C6-haloalkenyl, C2-C6-haloalkynyl, Cs-Cs-cycloalkyl, C3-Cs-cycloalkyl-Ci-C₄-alkyl, Ci-Ce-alkylsulfonyl,

phenyl or wherein the aliphatic, alicyclic and aromatic groups of R³ in each case either do not carry any further substituents or in each case may further carry one, two, three or up to the maximum possible number independently selected substituents R^3a as defined and preferably defined below.

In another aspect of the invention R³ is hydrogen, Ci-C6-alkyl, C2-C6-alkenyl, C2-C6- alkynyl, Ci-C₄-alkoxy-Ci-C6-alkyl, C(=0)-Ci-C₄-alkyl, Ci-C6-alkylsulfonyl, phenyl or phenyl-Ci-C₄-alkyl, wherein the aliphatic and aromatic groups of R³ in each case either do not carry any further substituents or in each case may further carry one, two, three or up to the maximum possible number of independently selected substituents R^3a as defined and preferably defined below.

In a further preferred aspect of the invention R³ is C(=0)-Ci-C4-alkyl, in particular COCH3. In another preferred aspect R³ is Ci-C6-alkylsulfonyl, in particular

methylsulfonyl.

In another aspect of the invention R³ is Ci-C6-alkyl, preferably Ci-C4-alkyl, in particular methyl or ethyl. In a further preferred aspect R³ is C2-C6-alkenyl, in particular

2-propenyl. In yet another preferred embodiment R³ is C2-C6-alkynyl, in particular 2-propynyl or 2-butynyl.

According to one further specific embodiment, R³ is phenyl, which is unsubstituted or carries one, two, three or up to the maximum possible number of independently selected substituents R^3a as defined and preferably defined below. According to another preferred embodiment R³ is phenyl-Ci-C4-alkyl, in particular benzyl, wherein the aromatic moiety is unsubstituted or carries one, two, three or up to the maximum possible number of independently selected substituents R^3a as defined and preferably defined below.

In one specific embodiment of the invention R³ is Ci-C4-alkoxy-Ci-C6-alkyl, in particular methoxymethyl.

R^3a according to the invention is independently selected from a group consisting of halogen, CN, N0₂, OH, Ci-C₄-alkyl, Ci-C₄-halogenalkyl, C₃-C₈-cycloalkyl, Ci-C₄-alkoxy and Ci-C4-halogenalkoxy.

In a preferred embodiment, R^3a is independently selected from the group consisting of halogen, in particular F and CI, Ci-C4-alkoxy, in particular methoxy, and Ci-C4-alkyl, in particular methyl and ethyl.

R⁴ according to the present invention is independently selected from the group consisting of halogen, CN, NO2, OH, SH, d-Ce-alkyl, d-Ce-alkoxy, d-Ce-alkylthio, Ci-C6-alkylsulfinyl, Ci-C6-alkylsulfonyl, C2-C6-alkenyl, C2-C6-alkynyl, Cs-Cs-cycloalkyl, Cs-Cs-cycloalkyloxy, NH₂, NH(Ci-C₄-alkyl), N(Ci-C₄-alkyl)₂, NH(C₃-C₆-cycloalkyl), N(C₃-C₆-cycloalkyl)₂, C(=0)-Ci-C₄-alkyl, C(=0)OH, C(=0)-0-Ci-C₄-alkyl,

C(=0)-NH(Ci-C₄-alkyl), C(=0)-N(Ci-C₄-alkyl)₂, C(=0)-NH(C₃-C₆-cycloalkyl) and C(=0)-N(C3-C6-cycloalkyl)2; wherein the aliphatic and alicyclic moieties of R⁴ are unsubstituted or substituted by one, two, three or four or up to the maximum possible number of independently selected substituents R^4a; wherein R^4a is halogen, CN, NO2, OH, Ci-C₄-alkyl, Ci-C₄-haloalkyl, C₃-C₈-cycloalkyl, Ci-C₄-alkoxy or C1-C4- halogenalkoxy.

In another preferred embodiment R⁴ is independently selected from the group consisting of halogen, CN, NO2, OH, SH, Ci-C6-alkyl, Ci-C6-haloalkyl, Ci-C6-alkoxy, Ci-C6-haloalkoxy, Ci-C6-alkylthio, Ci-C6-haloalkylthio, Ci-C4-alkoxy-Ci-C4-alkyl,

C2-C6-alkenyl, C2-C6-alkynyl, C2-C6-haloalkenyl, C2-C6-haloalkynyl, Cs-Cs-cycloalkyl, C3-Cs-cycloalkyloxy and C3-C8-cycloalkyl-Ci-C4-alkyl. In one specific embodiment R⁴ is independently selected from the group consisting of halogen, CN, NO2, OH, d-Ce-alkyl, d-Ce-haloalkyl, d-Ce-alkoxy, d-Ce-haloalkoxy, d-dralkenyl, d-Gs-alkynyl, d-drhaloalkenyl and d-drhaloalkynyl.

In another preferred embodiment R⁴ is independently selected from the group consisting of halogen and d-C6-haloalkyl.

In a further preferred embodiment R⁴ is independently selected from the group consisting of 2-F, 3-F, 4-F, 2-CI, 3-CI, 4-CI, 4-Br, 4-1, 4-CH₃, 4-OCH₃, 2-CF₃, 3-CF₃, 4- CF₃, 2-CH F2, 3-CH F2, 4-CH F2, 2,4-F₂, 2,3-F₂, 2,5-F₂, 2,6-F₂, 3,4-F₂, 3,5-F₂, 2,4-CI₂, 2,3- Cl₂, 2,5-CI₂, 2,6-CI₂, 3,4-CI₂, 3,5-CI₂, 2,4-(CH₃)₂, 2,4-(CF₃)₂, 2,4-(CHF₂)₂, 2-F-4-CI, 2-F- 4-CF₃, 2-F-4-CH F2, 2-CI-4-F, 2-CI-4-CF₃, 2-CI-4-CHF₂, 2-CF₃-4-F, 2-CF₃-4-CI, 2-CF₃-4- CHF₂, 2-CH F2-4-F, 2-CH F2-4-CI, 2-CHF₂-4-CF₃, 2-CN, 3-CN, 4-CN, 2-F-4-CN, 2-CI-4- CN, 2-CF₃-4-CN and 2-CHF₂-4-CN.

In a further preferred embodiment R⁴ is independently selected from the group consisting of halogen, in particular fluorine and chlorine. In a particularly preferred aspect of the invention R⁴ is fluorine. In another particularly preferred aspect R⁴ is chlorine.

In another preferred embodiment of the invention R⁴ is independently selected from the group consisting of d-C6-haloalkyl, in particular CF₃ or CH F2. In yet another preferred aspect of the invention R⁴ is CN.

According to the invention n is 0, 1 , 2, 3 or 4. In a preferred embodiment n is 1 , 2, 3 or 4. In another preferred embodiment n is 0, 1 , 2 or 3. In another preferred embodiment n is 1 , 2 or 3. In a preferred aspect n is 0, 1 or 2. In still another preferred aspect n is 1 or 2. In a further preferred embodiment n is 1 . In yet another preferred embodiment the invention relates to compounds I wherein n is 2.

According to one embodiment of the invention n is 1 , 2, 3 or 4, in particular 1 , 2 or 3, wherein in each case one radical R⁴ is located in ortho-position of the phenyl ring. In another preferred aspect of the invention n is 1 , 2, 3 or 4, in particular 1 , 2 or 3, wherein in each case one radical R⁴ is located in para-position of the phenyl ring. In a preferred embodiment n is 1 , 2, 3 or 4, in particular 1 , 2 or 3, or particularly 1 or 2, wherein in each case one R⁴ is located in ortho- and one R⁴ is located in para-position of the phenyl ring. In still another preferred embodiment, n is 1 and this R⁴ is located in ortho- position of the phenyl ring. In a further preferred embodiment n is 1 and this R⁴ is located in para-position of the phenyl ring.

R⁵ and R⁶ according to the invention are independently selected from the group consisting of hydrogen, halogen, CN, NO2, OH, SH, Ci-C6-alkyl, Ci-C6-alkoxy, Ci-dr alkylthio, Ci-C6-alkylsulfinyl, Ci-C6-alkylsulfonyl, d-dralkenyl, d-Gs-alkynyl, C₃-C₃- cycloalkyl, C₃-C₈-cycloalkoxy, NH₂, NH(Ci-C₄-alkyl), N(Ci-C₄-alkyl)₂, NH(C₃-C₆- cycloalkyl), N(C₃-C₆-cycloalkyl)₂, C(=0)-Ci-C₄-alkyl, C(=0)OH, C(=0)-0-Ci-C₄-alkyl, C(=0)-NH(Ci-C₄-alkyl) or C(=0)-N(Ci-C₄-alkyl)₂, C(=0)-NH(C₃-C₆-cycloalkyl) and C(=0)-N(C₃-C6-cycloalkyl)2; wherein the aliphatic and alicyclic moieties of R⁵ and/or R⁶ are unsubstituted or substituted by one, two, three or four or up to the maximum possible number of independently selected substituents R⁵¹ ; wherein R⁵¹ is halogen, CN, N0₂, OH, SH, NH2, d-Ce-alkyl, Ci-C₆-haloalkyl, d-C₆-alkoxy, Ci-C₆-haloalkoxy, Ci-C6-alkylthio, Ci-C6-haloalkylthio, Cs-Cs-cycloalkyl and Ci-C4-alkoxy-Ci-C4-alkyl; or R⁵ and R⁶ together with the carbon atom to which they are bound form a saturated or partially unsaturated three-, four-, five-, six- or seven-membered carbocycle or a saturated or partially unsaturated three-, four-, five-, six- or seven-membered heterocycle, wherein the heterocycle includes beside carbon atoms one, two, three or four heteroatoms independently selected from the group consisting of N, O and S, and wherein the carbo- and heterocycle are unsubstituted or carry one, two, three or four independently selected substituents R⁵⁶, wherein one or two CH2 groups of the carbo- or heterocycle may be replaced by one or two groups independently selected from the group of C(=0) and C(=S); wherein R⁵⁶ is halogen, CN, N0₂, OH, SH, NH₂, Ci-Ce-alkyl, Ci-C6-haloalkyl, Ci-C6-alkoxy, Ci-C6-haloalkoxy, Ci-C6-alkylthio, Ci-C6-haloalkylthio or Ci-C4-alkoxy-Ci-C4-alkyl; or R⁵ and R⁶ together with the carbon atom to which they are bound (denominated as C*) form a vinyl group C*=CR⁵²R⁵³, wherein R⁵² and R⁵³ are independently selected from the group consisting of hydrogen, halogen, CN, NO2, OH, SH, NH₂, Ci-Ce-alkyl, Ci-C₆-haloalkyl, d-C₆-alkoxy, Ci-C₆-haloalkoxy, Ci-C₆-alkylthio, Ci-C6-haloalkylthio and Ci-C4-alkoxy-Ci-C4-alkyl; or R⁵ and R⁶ together with the carbon atom to which they are bound (denominated as C*) form a group selected from C*(=S), C^*(=0) and C*(=NOR"); wherein R" is hydrogen, Ci-Ce-alkyl, Ci-C₆-haloalkyl,

C2-C6-alkenyl, C2-C6-alkynyl or Ci-C4-alkoxy-Ci-C4-alkyl.

In another aspect R⁵ and R⁶ are independently selected from the group consisting of hydrogen, halogen, CN, N0₂, OH, SH , Ci-Ce-alkyl, d-Ce-hydroxyalkyl, d-Ce-haloalkyl, Ci-C6-alkoxy, Ci-C6-haloalkoxy, Ci-C6-alkylthio, Ci-C6-haloalkylthio, Ci-d-alkoxy- Ci-d-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C2-C6-haloalkenyl, C2-C6-haloalkynyl, Cs-Cs- cycloalkyl, C3-Cs-cycloalkyloxy and C3-C8-cycloalkyl-Ci-C4-alkyl.

In a further preferred embodiment R⁵ and R⁶ are independently selected from the group consisting of hydrogen, halogen, CN, Ci-C6-alkyl, Ci-C6-haloalkyl, Ci-C6-alkoxy, C1-C6- haloalkoxy, Ci-C4-alkoxy-Ci-C4-alkyl, d-dralkenyl, C2-C6-alkynyl, Cs-Cs-cycloalkyl and C3-Cs-cycloa I kyl-Ci -C4-a I kyl .

In still another preferred embodiment R⁵ and R⁶ are independently selected from the group consisting of hydrogen, halogen, Ci-C6-alkyl, Ci-C6-haloalkyl, Ci-C6-alkoxy, Ci-C6-haloalkoxy and Cs-Cs-cycloalkyl.

In a preferred embodiment R⁵ and R⁶ are Ci-C4-alkyl, in particular methyl.

In still another preferred embodiment R⁵ is hydrogen and R⁶ is halogen, CN, Ci-dr alkyl, Ci-C6-haloalkyl, Ci-C6-alkoxy, Ci-C6-haloalkoxy, Ci-C4-alkoxy-Ci-C4-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, Cs-Cs-cycloalkyl and Cs-Cs-cycloalkyl-Ci-d-alkyl.

In still another preferred embodiment R⁵ is hydrogen and R⁶ is halogen, Ci-C6-alkyl, Ci-C6-haloalkyl, Ci-C6-alkoxy, Ci-C6-haloalkoxy and Cs-Cs-cycloalkyl.

In still another preferred embodiment R⁵ is hydrogen and R⁶ is Ci-C6-alkyl, in particular methyl. According to another preferred embodiment R⁵ and R⁶ are hydrogen. In one aspect of the invention R⁵ and R⁶ together with the carbon atom to which they are bound form a saturated or partially unsaturated three-, four-, five-, six- or seven- membered, in particular three-, four- or five-membered, carbocycle or a saturated or partially unsaturated three-, four-, five-, six- or seven-membered, in particular three-, four- or five-membered heterocycle, wherein the heterocycle includes beside carbon atoms one, two, three or four heteroatoms independently selected from the group consisting of N, O and S, and wherein the carbo- and heterocycle are unsubstituted or carry one, two, three or four, in particular one or two, independently selected substituents R⁵¹ as defined or preferaby defined below; and wherein one or two Chb groups of the carbo- or heterocycle may be replaced by one or two groups

independently selected from the group of C(=0) and C(=S), such as in, for example, cyclopropanone, cyclopentanone, cyclopropanethione, cyclopentanethione, 5- oxazolone, cyclohexane-1 ,4-dione, cyclohexane-1 ,4-dithione, cyclohex-2-ene- 1 ,4-dione or cyclohex-2-ene-1 ,4-dithione;

In one specific aspect of the invention R⁵ and R⁶ together with the carbon atom to which they are bound form a saturated or partially unsaturated three-, four-, five-, six- or seven-membered, in particular three-, four- or five-membered, carbocycle which is unsubstituted or carries one, two, three or four independently selected substituents R⁵¹ as defined or preferaby defined below.

In another preferred aspect R⁵ and R⁶ together with the carbon atom to which they are bound form a carbocycle selected from the group consisting of cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl and cycloheptyl and wherein the carbocycle is unsubstituted or carries one, two, three or four independently selected substituents R⁵¹ as defined or preferaby defined below.

In one further aspect R⁵ and R⁶ together with the carbon atom to which they are bound form a carbocycle selected from the group consisting cyclopentenyl, cyclopentadienyl and cyclohexenyl and wherein the carbocycle is unsubstituted or carries one, two, three or four independently selected substituents R⁵¹ as defined or preferaby defined below.

In a further preferred embodiment R⁵ and R⁶ together with the carbon atom to which they are bound form a cyclopropyl ring which is unsubstituted or carries one, two, three or four independently selected substituents R⁵¹ as defined or preferaby defined below. In another preferred embodiment R⁵ and R⁶ together with the carbon atom to which they are bound form a cyclobutyl ring which is unsubstituted or carries one, two, three or four independently selected substituents R⁵¹ as defined or preferaby defined below. In still another preferred aspect R⁵ and R⁶ together with the carbon atom to which they are bound form a cyclopentyl ring which is unsubstituted or carries one, two, three or four independently selected substituents R⁵¹ as defined or preferaby defined below. In yet another preferred aspect R⁵ and R⁶ together with the carbon atom to which they are bound form a cyclohexyl ring which is unsubstituted or carries one, two, three or four independently selected substituents R⁵¹ as defined or preferaby defined below. In one embodiment of the invention R⁵ and R⁶ together with the carbon atom to which they are bound form a saturated or partially unsaturated three-, four-, five-, six- or seven-membered heterocycle, wherein the heterocycle includes beside carbon atoms one, two, three or four heteroatoms independently selected from the group consisting of N, O and S, and wherein the heterocycle is unsubstituted or carries one, two, three or four independently selected substituents R⁵¹ as defined or preferaby defined below. According to a further aspect of the invention R⁵ and R⁵ together with the carbon atom to which they are bound form a three-, four-, five-, six- or seven-membered

heterocycle, wherein the heterocycle includes beside carbon atoms one, two, three or four heteroatoms independently selected from the group consisting of N, O and S, and wherein the carbo- and heterocycle are unsubstituted or carry one, two, three or four substituents R⁵¹ as defined or preferaby defined below.

In one aspect R⁵ and R⁵ together with the carbon atom to which they are bound form a heterocycle selected from the group consisting of oxirane, aziridine, thiirane, oxetane, azetidine, thiethane, 2-tetrahydrofuranyl, 3-tetrahydrofuranyl, 2-tetrahydrothienyl and 3- tetrahydrothienyl, wherein the heterocycle is unsubstituted or carries one, two, three or four independently selected substituents R⁵¹ as defined or preferaby defined below. In a preferred embodiment R⁵ and R⁶ together with the carbon atom to which they are bound form an oxirane which is unsubstituted or carries one, two, three or four independently selected substituents R⁵¹. In a further preferred embodiment R⁵ and R⁶ together with the carbon atom to which they are bound form an oxetane which is unsubstituted or carries one, two, three or four independently selected substituents R⁵¹ as defined or preferaby defined below. R⁵¹ according to the invention in each case is independently selected from the group consisting of halogen, CN, N0₂, OH, SH, NH₂, Ci-C₆-alkyl, d-C₆-haloalkyl,

Ci-C6-alkoxy, Ci-C6-haloalkoxy, Ci-C6-alkylthio, Ci-C6-haloalkylthio, Cs-Cs-cycloalkyl and Ci-C4-alkoxy-Ci-C4-alkyl.

In a preferred aspect R⁵¹ in each case preferably is halogen, CN, NO2, OH, SH, NH2, d-Ce-alkyl, Ci-C₆-haloalkyl, Ci-C₆-alkoxy, Ci-C₆-haloalkoxy, Ci-C₆-alkylthio, Ci-C₆- haloalkylthio or Ci-C4-alkoxy-Ci-C4-alkyl. In another preferred embodiment R⁵¹ in each case is halogen, CN, Ci-C6-alkyl, Ci-C6-haloalkyl, Ci-C6-alkoxy or Ci-C6-haloalkoxy. In a further preferred embodiment R⁵¹ is halogen, CN or Ci-C6-alkyl. In yet another preferred embodiment R⁵¹ in each case is halogen, in particular fluorine. According to one specific aspect R⁵¹ in each case is chlorine. According to a further preferred aspect R⁵¹ in each case is Ci-C6-alkyl, in particular methyl.

R⁷ accding to the invention is hydrogen, halogen, CN, Ci-C6-alkyl, Ci-C6-haloalkyl, Ci-C6-alkoxy or Ci-C6-haloalkoxy. In one aspect of the invention R⁷ is hydrogen, halogen, CN or Ci-C6-alkyl. In a preferred embodiment R⁷ is hydrogen. In another preferred embodiment R⁷ is halogen, in particular fluorine or chlorine. Y according to the invention is a direct bond or a divalent radical selected from -0-, -S(=0)p-, -CR^Y1R^Y2-, -N(R^YN)-, -CR^Y3R^Y4-CR^Y5R^Y6-, -CR^Y7=C^Y8- and -C≡C-, wherein R^YN, R^Y1, R^Y2, R^Y3, R^Y4, R^Y5, R^Y6, R^Y7 and R^Y8 are as defined or preferably defined below; and wherein p is 0, 1 or 2.

In another peferred embodiment Y is a direct bond or a divalent radical selected from -0-, -S(=0)₂-, -CH2-, -CH2-CH2-, -CH=CH- or -C≡C-. In a further peferred embodiment

Y is a direct bond or a divalent radical selected from -0-, -S-, -S(=0)2- or -CH2-.

In a further aspect of the present invention Y is a direct bond, -O- or -CH2-.

In another aspect Y is a direct bond. Still another aspect relates to compounds wherein Y is -0-. In still another aspect Y is -S-. According to a further aspect of the invention Y is -S(=0)2-. According to yet another peferred embodiment Y is -CH2-.

R^YN, R^Y , R^Y2, R^Y3, R^Y4, R^Y5, R^Y6, R^Y7 and R^Y8 according to the invention are

independently selected from the group consisting of hydrogen, halogen, CN, nitro, OH, Ci-C4-alkyl, Ci-C4-halogenalkyl, Ci-C4-alkoxy and Ci-C4-halogenalkoxy.

In one preferred aspect of the invention R^YN, R^Y , R^Y2, R^Y3, R^Y4, R^Y5, R^Y6, R^Y7 and R^Y8 are independently selected from the group consisting of hydrogen and halogen, in particular fluorine or chlorine. In a further preferred aspect R^YN, R^Y1, R^Y2, R^Y3, R^Y4, R^Y5, R^Y6, R^Y7 and R^Y8 are independently selected from the group consisting of hydrogen and Ci-C₄-alkyl, in particular methyl or ethyl. In a preferred aspect R^YN, R^Y1, R^Y2, R^Y3, R^Y4, R^Y5, R^Y6, R^Y7 and R^Y8 are independently selected from the group consisting of hydrogen and Ci-C4-alkoxy, in particular methoxy and ethoxy. In another preferred aspect R^YN, R^Y1, R^Y2, R^Y3, R^Y4, R^Y5, R^Y6, R^Y7 and R^Y8 are independently selected from hydrogen or CN. In yet another preferred aspect R^YN, R^Y , R^Y2, R^Y3, R^Y4, R^Y5, R^Y6, R^Y7 and R^Y8 are independently selected from hydrogen or OH.

Z according to the invention is phenyl or a five- or six-membered heteroaryl, wherein the aromatic moiety is unsubstituted or carries one, two, three or four independently selected radicals R^L as defined or preferably defined below.

In a peferred embodiment Z is phenyl or a five- or six-membered heteroaryl selected from the group consisting of pyrimidin-2-yl, pyrimidin-3-yl, pyrimidin-4-yl, pyridin-2-yl, pyridin-3-yl, pyridin-4-yl, thiazol-2-yl, thiazol-4-yl, thiazol-5-yl, isothiazol-3-yl, isothiazol- 4-yl, isothiazol-5-yl, pyrazin-2-yl, pyridazin-3-yl, 1 ,3,5-triazin-2-yl and 1 ,2,4-triazin-3-yl; and wherein the phenyl or heteroaryl carry one, two, three or four independently selected radicals R^L as defined or preferably defined below.

In another peferred embodiment Z is phenyl which is unsubstituted or carries one, two, three or four independently selected radicals R^L as defined or preferably defined below. In a further peferred embodiment Z is a five- or six-membered heteroaryl which is unsubstituted or carries one, two, three or four independently selected radicals R^L as defined or preferably defined below.

In a further peferred embodiment Z is a five-membered heteroaryl which is

unsubstituted or carries one, two, three or four independently selected radicals R^L as defined or preferably defined below. In a further peferred embodiment Z is a six-membered heteroaryl which is

unsubstituted or carries one, two, three or four independently selected radicals R^L as defined or preferably defined below.

According to one preferred aspect of the invention Z is selected from the group consisting of pyrimidin-2-yl, pyrimidin-3-yl, pyrimidin-4-yl, pyridin-2-yl, pyridin-3-yl, pyridin-4-yl, thiazol-2-yl, pyrazin-2-yl, pyridazin-3-yl, 1 ,3,5-triazin-2-yl, and 1 ,2,4-triazin- 3-yl; preferably Z is pyrimidin-2-yl, pyridin-2-yl, pyridin-3-yl, pyridin-4-yl and thiazol-2-yl, which are unsubstituted or carry one, two, three or four independently selected radicals R^L as defined or preferably defined below.

In a further preferred embodiment Z is substituted by exactly one radical R^L as defined or preferably defined below. In still another preferred embodiment Z is substituted by two independently selected radicals R^L as defined or preferably defined below. In yet another preferred embodiment Z is substituted by three independently selected radicals R^L as defined or preferably defined below. In another preferred embodiment Z is substituted by four independently selected radicals R^L as defined or preferably defined below.

R^L according to the invention is independently selected from the group consisting of halogen, CN , N0₂, OH , SH , d-C₆-alkyl, Ci-C₆-alkoxy, Ci-C₆-alkylthio, Ci-C₆-alkylsul- finyl, Ci-C6-alkylsulfonyl, C2-C6-alkenyl, C2-C6-alkynyl, d-Cs-cycloalkyl, C₃-C₃- cycloalkyloxy, C₃-C₈-cycloalkyl-Ci-C₄-alkyl, N H₂, N H(Ci-C₄-alkyl), N(Ci-C₄-alkyl)₂, N H(C₃-C₆-cycloalkyl), N(C₃-C₆-cycloalkyl)₂, C(=0)-Ci-C₄-alkyl, C(=0)OH ,

C(=0)-0-Ci-C₄-alkyl, C(=0)-N H(Ci-C₄-alkyl), C(=0)-N(Ci-C₄-alkyl)₂, C(=0)-N H (C₃-C₆- cycloalkyl), C(=0)-N(C₃-C6-cycloalkyl)₂, phenyl and phenyl-Ci-C₄-alkyl , wherein the aliphatic, alicyclic and aromatic moieties are unsubstituted or substituted by one, two, three or four or up to the maximum possible number of independently selected substituents R^La; wherein R^La is halogen, CN , N0₂, OH , SH , N H₂, d-Ce-alkyl, Ci-Ce- haloalkyI, Ci-C6-alkoxy, Ci-C6-haloalkoxy, Ci-C6-alkylthio, Ci-C6-haloalkylthio or C₃-C₃- cycloalkyl.

In another embodiment of the invention R^L is independently selected from the group consisting of halogen, CN , N0₂, OH , SH , d-Ce-alkyl, d-Ce-hydroxyalkyl, Ci-Ce- haloalkyl, Ci-C6-alkoxy, Ci-C6-haloalkoxy, Ci-C6-alkylthio, Ci-drhaloalkylthio, C1-C6- alkylsulfinyl, Ci-C6-haloalkylsulfinyl, Ci-C6-alkylsulfonyl, Ci-C6-haloalkylsulfonyl, Ci-C₄- alkoxy-Ci-C₄-alkyl, Ci-C₄-alkoxy-Ci-C₄-alkoxy, C₂-C6-alkenyl, C₂-C6-alkynyl,

C₂-C6-haloalkenyl, C₂-C6-haloalkynyl, C₃-C8-cycloalkyl, d-Cs-cycloalkyloxy, C₃-C₃- cycloalkyl-Ci-C₄-alkyl and N H₂, N H(Ci-C₄-alkyl).

In still another embodiment R^L is independently selected from the group consisting of halogen, CN , OH , Ci-C6-alkyl, Ci-drhaloalkyl, Ci-C6-alkoxy and Ci-C6-haloalkoxy. In a further preferred embodiment R^L is independently selected from the group consisting of halogen, in particular fluorine or chlorine. In a further preferred aspect R^L is independently selected from the group consisting of Ci-C6-haloalkyl, in particular CF₃ or CH F₂. In one preferred embodiment R^L is CN . In still a further embodiment R^L is independently selected from the group consisting of 2-F, 3-F, 4-F, 2-CI, 3-CI, 4-CI, 2-CF₃, 3-CF₃, 4-CF₃, 2,4-F₂, 2,4-CI₂, 2,6-CI₂, 2-CN, 3-CN, 4- CN, 2-F-4-CN and 2-CI-4-CN. According to the invention m is 0 or 1. In a preferred embodiment m is 1 . In another preferred embodiment m is 0.

According to one preferred embodiment of the invention the group Z-Y- is attached to the phenyl ring in para-position with respect to the triazole bearing residue. In a further preferred embodiment the group Z-Y- is attached to the phenyl ring in metha-position with respect to the triazole bearing moiety.

According to further preferred embodiments of the invention R¹, R², D, X, Y and the position of Y with regards to the triazole bearing residue in each case are one of the following combinations of lines A-1 to A-2688 in table A.

Table A:

Line R¹ R² D X Y Pos.

A-131 OH H SH OH -0- para

A-132 NH₂ H SH OH -0- para

A-133 N(CH₃)₂ H SH OH -0- para

A-134 CHs CH₃ SH OH -0- para

A-135 CH2CH3 CH2CH3 SH OH -0- para

A-136 =CH₂ SH OH -0- para

A-137 cyclopropyl SH OH -0- para

A-138 cyclobutyl SH OH -0- para

A-139 cyclopentyl SH OH -0- para

A-140 cyclohexyl SH OH -0- para

A-141 1-triazolyl H SH OH -0- para

A-142 2-pyridinyl H SH OH -0- para

A-143 3-pyridinyl H SH OH -0- para

A-144 4-pyridinyl H SH OH -0- para

A-145 CHs H S-allyl OH -0- para

A-146 CH2CH3 H S-allyl OH -0- para

A-147 CH2CH2CH3 H S-allyl OH -0- para

A-148 CH(CH₃)₂ H S-allyl OH -0- para

A-149 OCH3 H S-allyl OH -0- para

A-150 OCH2CH3 H S-allyl OH -0- para

A-151 OCH(CH₃)₂ H S-allyl OH -0- para

A-152 F H S-allyl OH -0- para

A-153 CI H S-allyl OH -0- para

A-154 Br H S-allyl OH -0- para

A-155 OH H S-allyl OH -0- para

A-156 NH2 H S-allyl OH -0- para

A-157 N(CH₃)₂ H S-allyl OH -0- para

A-158 CH₃ CH₃ S-allyl OH -0- para

A-159 CH2CH3 CH2CH3 S-allyl OH -0- para

A-160 =CH₂ S-allyl OH -0- para

A-161 cyclopropyl S-allyl OH -0- para

A-162 cyclobutyl S-allyl OH -0- para

A-163 cyclopentyl S-allyl OH -0- para

A-164 cyclohexyl S-allyl OH -0- para

A-165 1-triazolyl H S-allyl OH -0- para

A-166 2-pyridinyl H S-allyl OH -0- para Line R¹ R² D X Y Pos.

A-167 3-pyridinyl H S-allyl OH -0- para

A-168 4-pyridinyl H S-allyl OH -0- para

A-169 CHs H SCN OH -0- para

A-170 CH2CH3 H SCN OH -0- para

A-171 CH2CH2CH3 H SCN OH -0- para

A-172 CH(CH₃)₂ H SCN OH -0- para

A-173 OCH3 H SCN OH -0- para

A-174 OCH2CH3 H SCN OH -0- para

A-175 OCH(CH₃)₂ H SCN OH -0- para

A-176 F H SCN OH -0- para

A-177 CI H SCN OH -0- para

A-178 Br H SCN OH -0- para

A-179 OH H SCN OH -0- para

A-180 NH2 H SCN OH -0- para

A-181 N(CH₃)₂ H SCN OH -0- para

A-182 CH₃ CH₃ SCN OH -0- para

A-183 CH₂CH₃ CH₂CH₃ SCN OH -0- para

A-184 =CH₂ SCN OH -0- para

A-185 cyclopropyl SCN OH -0- para

A-186 cyclobutyl SCN OH -0- para

A-187 cyclopentyl SCN OH -0- para

A-188 cyclohexyl SCN OH -0- para

A-189 1 -triazolyl H SCN OH -0- para

A-190 2-pyridinyl H SCN OH -0- para

A-191 3-pyridinyl H SCN OH -0- para

A-192 4-pyridinyl H SCN OH -0- para

A-193 CH₃ H H methoxy -0- para

A-194 CH₂CH₃ H H methoxy -0- para

A-195 CH2CH2CH₃ H H methoxy -0- para

A-196 CH(CH₃)₂ H H methoxy -0- para

A-197 OCH₃ H H methoxy -0- para

A-198 OCH₂CH₃ H H methoxy -0- para

A-199 OCH(CH₃)₂ H H methoxy -0- para

A-200 F H H methoxy -0- para

A-201 CI H H methoxy -0- para

A-202 Br H H methoxy -0- para

Line R¹ R² D X Y Pos.

A-239 3-pyridinyl H SH methoxy -0- para

A-240 4-pyridinyl H SH methoxy -0- para

A-241 CHs H S-allyl methoxy -0- para

A-242 CH2CH3 H S-allyl methoxy -0- para

A-243 CH2CH2CH3 H S-allyl methoxy -0- para

A-244 CH(CH₃)₂ H S-allyl methoxy -0- para

A-245 OCH3 H S-allyl methoxy -0- para

A-246 OCH2CH3 H S-allyl methoxy -0- para

A-247 OCH(CH₃)₂ H S-allyl methoxy -0- para

A-248 F H S-allyl methoxy -0- para

A-249 CI H S-allyl methoxy -0- para

A-250 Br H S-allyl methoxy -0- para

A-251 OH H S-allyl methoxy -0- para

A-252 NH2 H S-allyl methoxy -0- para

A-253 N(CH₃)₂ H S-allyl methoxy -0- para

A-254 CH₃ CH₃ S-allyl methoxy -0- para

A-255 CH₂CH₃ CH₂CH₃ S-allyl methoxy -0- para

A-256 =CH₂ S-allyl methoxy -0- para

A-257 cyclopropyl S-allyl methoxy -0- para

A-258 cyclobutyl S-allyl methoxy -0- para

A-259 cyclopentyl S-allyl methoxy -0- para

A-260 cyclohexyl S-allyl methoxy -0- para

A-261 1 -triazolyl H S-allyl methoxy -0- para

A-262 2-pyridinyl H S-allyl methoxy -0- para

A-263 3-pyridinyl H S-allyl methoxy -0- para

A-264 4-pyridinyl H S-allyl methoxy -0- para

A-265 CH₃ H SCN methoxy -0- para

A-266 CH₂CH₃ H SCN methoxy -0- para

A-267 CH2CH2CH₃ H SCN methoxy -0- para

A-268 CH(CH₃)₂ H SCN methoxy -0- para

A-269 OCH₃ H SCN methoxy -0- para

A-270 OCH₂CH₃ H SCN methoxy -0- para

A-271 OCH(CH₃)₂ H SCN methoxy -0- para

A-272 F H SCN methoxy -0- para

A-273 CI H SCN methoxy -0- para

A-274 Br H SCN methoxy -0- para

Line R¹ R² D X Y Pos.

A-31 1 3-pyridinyl H H ethoxy -0- para

A-312 4-pyridinyl H H ethoxy -0- para

A-313 CHs H SH ethoxy -0- para

A-314 CH2CH3 H SH ethoxy -0- para

A-315 CH2CH2CH3 H SH ethoxy -0- para

A-316 CH(CH₃)₂ H SH ethoxy -0- para

A-317 OCH3 H SH ethoxy -0- para

A-318 OCH2CH3 H SH ethoxy -0- para

A-319 OCH(CH₃)₂ H SH ethoxy -0- para

A-320 F H SH ethoxy -0- para

A-321 CI H SH ethoxy -0- para

A-322 Br H SH ethoxy -0- para

A-323 OH H SH ethoxy -0- para

A-324 NH2 H SH ethoxy -0- para

A-325 N(CH₃)₂ H SH ethoxy -0- para

A-326 CH₃ CH₃ SH ethoxy -0- para

A-327 CH₂CH₃ CH₂CH₃ SH ethoxy -0- para

A-328 =CH₂ SH ethoxy -0- para

A-329 cyclopropyl SH ethoxy -0- para

A-330 cyclobutyl SH ethoxy -0- para

A-331 cyclopentyl SH ethoxy -0- para

A-332 cyclohexyl SH ethoxy -0- para

A-333 1 -triazolyl H SH ethoxy -0- para

A-334 2-pyridinyl H SH ethoxy -0- para

A-335 3-pyridinyl H SH ethoxy -0- para

A-336 4-pyridinyl H SH ethoxy -0- para

A-337 CH₃ H S-allyl ethoxy -0- para

A-338 CH₂CH₃ H S-allyl ethoxy -0- para

A-339 CH2CH2CH₃ H S-allyl ethoxy -0- para

A-340 CH(CH₃)₂ H S-allyl ethoxy -0- para

A-341 OCH₃ H S-allyl ethoxy -0- para

A-342 OCH₂CH₃ H S-allyl ethoxy -0- para

A-343 OCH(CH₃)₂ H S-allyl ethoxy -0- para

A-344 F H S-allyl ethoxy -0- para

A-345 CI H S-allyl ethoxy -0- para

A-346 Br H S-allyl ethoxy -0- para

Line R¹ R² D X Y Pos.

A-455 3-pyridinyl H S-allyl O-allyl -0- para

A-456 4-pyridinyl H S-allyl O-allyl -0- para

A-457 CHs H SCN O-allyl -0- para

A-458 CH2CH3 H SCN O-allyl -0- para

A-459 CH2CH2CH3 H SCN O-allyl -0- para

A-460 CH(CH₃)₂ H SCN O-allyl -0- para

A-461 OCH3 H SCN O-allyl -0- para

A-462 OCH2CH3 H SCN O-allyl -0- para

A-463 OCH(CH₃)₂ H SCN O-allyl -0- para

A-464 F H SCN O-allyl -0- para

A-465 CI H SCN O-allyl -0- para

A-466 Br H SCN O-allyl -0- para

A-467 OH H SCN O-allyl -0- para

A-468 NH2 H SCN O-allyl -0- para

A-469 N(CH₃)₂ H SCN O-allyl -0- para

A-470 CH₃ CH₃ SCN O-allyl -0- para

A-471 CH₂CH₃ CH₂CH₃ SCN O-allyl -0- para

A-472 =CH₂ SCN O-allyl -0- para

A-473 cyclopropyl SCN O-allyl -0- para

A-474 cyclobutyl SCN O-allyl -0- para

A-475 cyclopentyl SCN O-allyl -0- para

A-476 cyclohexyl SCN O-allyl -0- para

A-477 1 -triazolyl H SCN O-allyl -0- para

A-478 2-pyridinyl H SCN O-allyl -0- para

A-479 3-pyridinyl H SCN O-allyl -0- para

A-480 4-pyridinyl H SCN O-allyl -0- para

A-481 CH₃ H H O-propargyl -0- para

A-482 CH₂CH₃ H H O-propargyl -0- para

A-483 CH2CH2CH₃ H H O-propargyl -0- para

A-484 CH(CH₃)₂ H H O-propargyl -0- para

A-485 OCH₃ H H O-propargyl -0- para

A-486 OCH₂CH₃ H H O-propargyl -0- para

A-487 OCH(CH₃)₂ H H O-propargyl -0- para

A-488 F H H O-propargyl -0- para

A-489 CI H H O-propargyl -0- para

A-490 Br H H O-propargyl -0- para Line R¹ R² D X Y Pos.

A-491 OH H H O-propargyl -0- para

A-492 NH₂ H H O-propargyl -0- para

A-493 N(CH₃)₂ H H O-propargyl -0- para

A-494 CHs CH₃ H O-propargyl -0- para

A-495 CH2CH3 CH2CH3 H O-propargyl -0- para

A-496 =CH₂ H O-propargyl -0- para

A-497 cyclopropyl H O-propargyl -0- para

A-498 cyclobutyl H O-propargyl -0- para

A-499 cyclopentyl H O-propargyl -0- para

A-500 cyclohexyl H O-propargyl -0- para

A-501 1-triazolyl H H O-propargyl -0- para

A-502 2-pyridinyl H H O-propargyl -0- para

A-503 3-pyridinyl H H O-propargyl -0- para

A-504 4-pyridinyl H H O-propargyl -0- para

A-505 CHs H SH O-propargyl -0- para

A-506 CH2CH3 H SH O-propargyl -0- para

A-507 CH2CH2CH3 H SH O-propargyl -0- para

A-508 CH(CH₃)₂ H SH O-propargyl -0- para

A-509 OCH3 H SH O-propargyl -0- para

A-510 OCH2CH3 H SH O-propargyl -0- para

A-51 1 OCH(CH₃)₂ H SH O-propargyl -0- para

A-512 F H SH O-propargyl -0- para

A-513 CI H SH O-propargyl -0- para

A-514 Br H SH O-propargyl -0- para

A-515 OH H SH O-propargyl -0- para

A-516 NH2 H SH O-propargyl -0- para

A-517 N(CH₃)₂ H SH O-propargyl -0- para

A-518 CH₃ CH₃ SH O-propargyl -0- para

A-519 CH2CH3 CH2CH3 SH O-propargyl -0- para

A-520 =CH₂ SH O-propargyl -0- para

A-521 cyclopropyl SH O-propargyl -0- para

A-522 cyclobutyl SH O-propargyl -0- para

A-523 cyclopentyl SH O-propargyl -0- para

A-524 cyclohexyl SH O-propargyl -0- para

A-525 1-triazolyl H SH O-propargyl -0- para

A-526 2-pyridinyl H SH O-propargyl -0- para Line R¹ R² D X Y Pos.

A-527 3-pyridinyl H SH O-propargyl -0- para

A-528 4-pyridinyl H SH O-propargyl -0- para

A-529 CHs H S-allyl O-propargyl -0- para

A-530 CH2CH3 H S-allyl O-propargyl -0- para

A-531 CH2CH2CH3 H S-allyl O-propargyl -0- para

A-532 CH(CH₃)₂ H S-allyl O-propargyl -0- para

A-533 OCH3 H S-allyl O-propargyl -0- para

A-534 OCH2CH3 H S-allyl O-propargyl -0- para

A-535 OCH(CH₃)₂ H S-allyl O-propargyl -0- para

A-536 F H S-allyl O-propargyl -0- para

A-537 CI H S-allyl O-propargyl -0- para

A-538 Br H S-allyl O-propargyl -0- para

A-539 OH H S-allyl O-propargyl -0- para

A-540 NH2 H S-allyl O-propargyl -0- para

A-541 N(CH₃)₂ H S-allyl O-propargyl -0- para

A-542 CH₃ CH₃ S-allyl O-propargyl -0- para

A-543 CH₂CH₃ CH₂CH₃ S-allyl O-propargyl -0- para

A-544 =CH₂ S-allyl O-propargyl -0- para

A-545 cyclopropyl S-allyl O-propargyl -0- para

A-546 cyclobutyl S-allyl O-propargyl -0- para

A-547 cyclopentyl S-allyl O-propargyl -0- para

A-548 cyclohexyl S-allyl O-propargyl -0- para

A-549 1 -triazolyl H S-allyl O-propargyl -0- para

A-550 2-pyridinyl H S-allyl O-propargyl -0- para

A-551 3-pyridinyl H S-allyl O-propargyl -0- para

A-552 4-pyridinyl H S-allyl O-propargyl -0- para

A-553 CH₃ H SCN O-propargyl -0- para

A-554 CH₂CH₃ H SCN O-propargyl -0- para

A-555 CH2CH2CH₃ H SCN O-propargyl -0- para

A-556 CH(CH₃)₂ H SCN O-propargyl -0- para

A-557 OCH₃ H SCN O-propargyl -0- para

A-558 OCH₂CH₃ H SCN O-propargyl -0- para

A-559 OCH(CH₃)₂ H SCN O-propargyl -0- para

A-560 F H SCN O-propargyl -0- para

A-561 CI H SCN O-propargyl -0- para

A-562 Br H SCN O-propargyl -0- para

Line R¹ R² D X Y Pos.

A-599 3-pyridinyl H H O-benzyl -0- para

A-600 4-pyridinyl H H O-benzyl -0- para

A-601 CHs H SH O-benzyl -0- para

A-602 CH2CH3 H SH O-benzyl -0- para

A-603 CH2CH2CH3 H SH O-benzyl -0- para

A-604 CH(CH₃)₂ H SH O-benzyl -0- para

A-605 OCH3 H SH O-benzyl -0- para

A-606 OCH2CH3 H SH O-benzyl -0- para

A-607 OCH(CH₃)₂ H SH O-benzyl -0- para

A-608 F H SH O-benzyl -0- para

A-609 CI H SH O-benzyl -0- para

A-610 Br H SH O-benzyl -0- para

A-61 1 OH H SH O-benzyl -0- para

A-612 NH2 H SH O-benzyl -0- para

A-613 N(CH₃)₂ H SH O-benzyl -0- para

A-614 CH₃ CH₃ SH O-benzyl -0- para

A-615 CH₂CH₃ CH₂CH₃ SH O-benzyl -0- para

A-616 =CH₂ SH O-benzyl -0- para

A-617 cyclopropyl SH O-benzyl -0- para

A-618 cyclobutyl SH O-benzyl -0- para

A-619 cyclopentyl SH O-benzyl -0- para

A-620 cyclohexyl SH O-benzyl -0- para

A-621 1 -triazolyl H SH O-benzyl -0- para

A-622 2-pyridinyl H SH O-benzyl -0- para

A-623 3-pyridinyl H SH O-benzyl -0- para

A-624 4-pyridinyl H SH O-benzyl -0- para

A-625 CH₃ H S-allyl O-benzyl -0- para

A-626 CH₂CH₃ H S-allyl O-benzyl -0- para

A-627 CH2CH2CH₃ H S-allyl O-benzyl -0- para

A-628 CH(CH₃)₂ H S-allyl O-benzyl -0- para

A-629 OCH₃ H S-allyl O-benzyl -0- para

A-630 OCH₂CH₃ H S-allyl O-benzyl -0- para

A-631 OCH(CH₃)₂ H S-allyl O-benzyl -0- para

A-632 F H S-allyl O-benzyl -0- para

A-633 CI H S-allyl O-benzyl -0- para

A-634 Br H S-allyl O-benzyl -0- para

Line R¹ R² D X Y Pos.

A-815 3-pyridinyl H SH OH -0- meta

A-816 4-pyridinyl H SH OH -0- meta

A-817 CHs H S-allyl OH -0- meta

A-818 CH2CH3 H S-allyl OH -0- meta

A-819 CH2CH2CH3 H S-allyl OH -0- meta

A-820 CH(CH₃)₂ H S-allyl OH -0- meta

A-821 OCH3 H S-allyl OH -0- meta

A-822 OCH2CH3 H S-allyl OH -0- meta

A-823 OCH(CH₃)₂ H S-allyl OH -0- meta

A-824 F H S-allyl OH -0- meta

A-825 CI H S-allyl OH -0- meta

A-826 Br H S-allyl OH -0- meta

A-827 OH H S-allyl OH -0- meta

A-828 NH2 H S-allyl OH -0- meta

A-829 N(CH₃)₂ H S-allyl OH -0- meta

A-830 CH₃ CH₃ S-allyl OH -0- meta

A-831 CH₂CH₃ CH₂CH₃ S-allyl OH -0- meta

A-832 =CH₂ S-allyl OH -0- meta

A-833 cyclopropyl S-allyl OH -0- meta

A-834 cyclobutyl S-allyl OH -0- meta

A-835 cyclopentyl S-allyl OH -0- meta

A-836 cyclohexyl S-allyl OH -0- meta

A-837 1 -triazolyl H S-allyl OH -0- meta

A-838 2-pyridinyl H S-allyl OH -0- meta

A-839 3-pyridinyl H S-allyl OH -0- meta

A-840 4-pyridinyl H S-allyl OH -0- meta

A-841 CH₃ H SCN OH -0- meta

A-842 CH₂CH₃ H SCN OH -0- meta

A-843 CH2CH2CH₃ H SCN OH -0- meta

A-844 CH(CH₃)₂ H SCN OH -0- meta

A-845 OCH₃ H SCN OH -0- meta

A-846 OCH₂CH₃ H SCN OH -0- meta

A-847 OCH(CH₃)₂ H SCN OH -0- meta

A-848 F H SCN OH -0- meta

A-849 CI H SCN OH -0- meta

A-850 Br H SCN OH -0- meta Line R¹ R² D X Y Pos.

A-851 OH H SCN OH -0- meta

A-852 NH₂ H SCN OH -0- meta

A-853 N(CH₃)₂ H SCN OH -0- meta

A-854 CHs CH₃ SCN OH -0- meta

A-855 CH2CH3 CH2CH3 SCN OH -0- meta

A-856 =CH₂ SCN OH -0- meta

A-857 cyclopropyl SCN OH -0- meta

A-858 cyclobutyl SCN OH -0- meta

A-859 cyclopentyl SCN OH -0- meta

A-860 cyclohexyl SCN OH -0- meta

A-861 1 -triazolyl H SCN OH -0- meta

A-862 2-pyridinyl H SCN OH -0- meta

A-863 3-pyridinyl H SCN OH -0- meta

A-864 4-pyridinyl H SCN OH -0- meta

A-865 CHs H H methoxy -0- meta

A-866 CH2CH3 H H methoxy -0- meta

A-867 CH2CH2CH3 H H methoxy -0- meta

A-868 CH(CH₃)₂ H H methoxy -0- meta

A-869 OCH3 H H methoxy -0- meta

A-870 OCH2CH3 H H methoxy -0- meta

A-871 OCH(CH₃)₂ H H methoxy -0- meta

A-872 F H H methoxy -0- meta

A-873 CI H H methoxy -0- meta

A-874 Br H H methoxy -0- meta

A-875 OH H H methoxy -0- meta

A-876 NH2 H H methoxy -0- meta

A-877 N(CH₃)₂ H H methoxy -0- meta

A-878 CH₃ CH₃ H methoxy -0- meta

A-879 CH2CH3 CH2CH3 H methoxy -0- meta

A-880 =CH₂ H methoxy -0- meta

A-881 cyclopropyl H methoxy -0- meta

A-882 cyclobutyl H methoxy -0- meta

A-883 cyclopentyl H methoxy -0- meta

A-884 cyclohexyl H methoxy -0- meta

A-885 1 -triazolyl H H methoxy -0- meta

A-886 2-pyridinyl H H methoxy -0- meta Line R¹ R² D X Y Pos.

A-887 3-pyridinyl H H methoxy -0- meta

A-888 4-pyridinyl H H methoxy -0- meta

A-889 CHs H SH methoxy -0- meta

A-890 CH2CH3 H SH methoxy -0- meta

A-891 CH2CH2CH3 H SH methoxy -0- meta

A-892 CH(CH₃)₂ H SH methoxy -0- meta

A-893 OCH3 H SH methoxy -0- meta

A-894 OCH2CH3 H SH methoxy -0- meta

A-895 OCH(CH₃)₂ H SH methoxy -0- meta

A-896 F H SH methoxy -0- meta

A-897 CI H SH methoxy -0- meta

A-898 Br H SH methoxy -0- meta

A-899 OH H SH methoxy -0- meta

A-900 NH2 H SH methoxy -0- meta

A-901 N(CH₃)₂ H SH methoxy -0- meta

A-902 CH₃ CH₃ SH methoxy -0- meta

A-903 CH₂CH₃ CH₂CH₃ SH methoxy -0- meta

A-904 =CH₂ SH methoxy -0- meta

A-905 cyclopropyl SH methoxy -0- meta

A-906 cyclobutyl SH methoxy -0- meta

A-907 cyclopentyl SH methoxy -0- meta

A-908 cyclohexyl SH methoxy -0- meta

A-909 1 -triazolyl H SH methoxy -0- meta

A-910 2-pyridinyl H SH methoxy -0- meta

A-91 1 3-pyridinyl H SH methoxy -0- meta

A-912 4-pyridinyl H SH methoxy -0- meta

A-913 CH₃ H S-allyl methoxy -0- meta

A-914 CH₂CH₃ H S-allyl methoxy -0- meta

A-915 CH2CH2CH₃ H S-allyl methoxy -0- meta

A-916 CH(CH₃)₂ H S-allyl methoxy -0- meta

A-917 OCH₃ H S-allyl methoxy -0- meta

A-918 OCH₂CH₃ H S-allyl methoxy -0- meta

A-919 OCH(CH₃)₂ H S-allyl methoxy -0- meta

A-920 F H S-allyl methoxy -0- meta

A-921 CI H S-allyl methoxy -0- meta

A-922 Br H S-allyl methoxy -0- meta

Line R¹ R² D X Y Pos.

A-959 3-pyridinyl H SCN methoxy -0- meta

A-960 4-pyridinyl H SCN methoxy -0- meta

A-961 CHs H H ethoxy -0- meta

A-962 CH2CH3 H H ethoxy -0- meta

A-963 CH2CH2CH3 H H ethoxy -0- meta

A-964 CH(CH₃)₂ H H ethoxy -0- meta

A-965 OCH3 H H ethoxy -0- meta

A-966 OCH2CH3 H H ethoxy -0- meta

A-967 OCH(CH₃)₂ H H ethoxy -0- meta

A-968 F H H ethoxy -0- meta

A-969 CI H H ethoxy -0- meta

A-970 Br H H ethoxy -0- meta

A-971 OH H H ethoxy -0- meta

A-972 NH2 H H ethoxy -0- meta

A-973 N(CH₃)₂ H H ethoxy -0- meta

A-974 CH₃ CH₃ H ethoxy -0- meta

A-975 CH₂CH₃ CH₂CH₃ H ethoxy -0- meta

A-976 =CH₂ H ethoxy -0- meta

A-977 cyclopropyl H ethoxy -0- meta

A-978 cyclobutyl H ethoxy -0- meta

A-979 cyclopentyl H ethoxy -0- meta

A-980 cyclohexyl H ethoxy -0- meta

A-981 1 -triazolyl H H ethoxy -0- meta

A-982 2-pyridinyl H H ethoxy -0- meta

A-983 3-pyridinyl H H ethoxy -0- meta

A-984 4-pyridinyl H H ethoxy -0- meta

A-985 CH₃ H SH ethoxy -0- meta

A-986 CH₂CH₃ H SH ethoxy -0- meta

A-987 CH2CH2CH₃ H SH ethoxy -0- meta

A-988 CH(CH₃)₂ H SH ethoxy -0- meta

A-989 OCH₃ H SH ethoxy -0- meta

A-990 OCH₂CH₃ H SH ethoxy -0- meta

A-991 OCH(CH₃)₂ H SH ethoxy -0- meta

A-992 F H SH ethoxy -0- meta

A-993 CI H SH ethoxy -0- meta

A-994 Br H SH ethoxy -0- meta

Line R¹ R² D X Y Pos.

A-1031 3-pyridinyl H S-allyl ethoxy -0- meta

A-1032 4-pyridinyl H S-allyl ethoxy -0- meta

A-1033 CHs H SCN ethoxy -0- meta

A-1034 CH2CH3 H SCN ethoxy -0- meta

A-1035 CH2CH2CH3 H SCN ethoxy -0- meta

A-1036 CH(CH₃)₂ H SCN ethoxy -0- meta

A-1037 OCH3 H SCN ethoxy -0- meta

A-1038 OCH2CH3 H SCN ethoxy -0- meta

A-1039 OCH(CH₃)₂ H SCN ethoxy -0- meta

A-1040 F H SCN ethoxy -0- meta

A-1041 CI H SCN ethoxy -0- meta

A-1042 Br H SCN ethoxy -0- meta

A-1043 OH H SCN ethoxy -0- meta

A-1044 NH2 H SCN ethoxy -0- meta

A-1045 N(CH₃)₂ H SCN ethoxy -0- meta

A-1046 CH₃ CH₃ SCN ethoxy -0- meta

A-1047 CH₂CH₃ CH₂CH₃ SCN ethoxy -0- meta

A-1048 =CH₂ SCN ethoxy -0- meta

A-1049 cyclopropyl SCN ethoxy -0- meta

A-1050 cyclobutyl SCN ethoxy -0- meta

A-1051 cyclopentyl SCN ethoxy -0- meta

A-1052 cyclohexyl SCN ethoxy -0- meta

A-1053 1 -triazolyl H SCN ethoxy -0- meta

A-1054 2-pyridinyl H SCN ethoxy -0- meta

A-1055 3-pyridinyl H SCN ethoxy -0- meta

A-1056 4-pyridinyl H SCN ethoxy -0- meta

A-1057 CH₃ H H O-allyl -0- meta

A-1058 CH₂CH₃ H H O-allyl -0- meta

A-1059 CH2CH2CH₃ H H O-allyl -0- meta

A-1060 CH(CH₃)₂ H H O-allyl -0- meta

A-1061 OCH₃ H H O-allyl -0- meta

A-1062 OCH₂CH₃ H H O-allyl -0- meta

A-1063 OCH(CH₃)₂ H H O-allyl -0- meta

A-1064 F H H O-allyl -0- meta

A-1065 CI H H O-allyl -0- meta

A-1066 Br H H O-allyl -0- meta

Line R¹ R² D X Y Pos.

A-1283 OH H SH O-benzyl -0- meta

A-1284 NH₂ H SH O-benzyl -0- meta

A-1285 N(CH₃)₂ H SH O-benzyl -0- meta

A-1286 CHs CH₃ SH O-benzyl -0- meta

A-1287 CH2CH3 CH2CH3 SH O-benzyl -0- meta

A-1288 =CH₂ SH O-benzyl -0- meta

A-1289 cyclopropyl SH O-benzyl -0- meta

A-1290 cyclobutyl SH O-benzyl -0- meta

A-1291 cyclopentyl SH O-benzyl -0- meta

A-1292 cyclohexyl SH O-benzyl -0- meta

A-1293 1 -triazolyl H SH O-benzyl -0- meta

A-1294 2-pyridinyl H SH O-benzyl -0- meta

A-1295 3-pyridinyl H SH O-benzyl -0- meta

A-1296 4-pyridinyl H SH O-benzyl -0- meta

A-1297 CHs H S-allyl O-benzyl -0- meta

A-1298 CH2CH3 H S-allyl O-benzyl -0- meta

A-1299 CH2CH2CH3 H S-allyl O-benzyl -0- meta

A-1300 CH(CH₃)₂ H S-allyl O-benzyl -0- meta

A-1301 OCH3 H S-allyl O-benzyl -0- meta

A-1302 OCH2CH3 H S-allyl O-benzyl -0- meta

A-1303 OCH(CH₃)₂ H S-allyl O-benzyl -0- meta

A-1304 F H S-allyl O-benzyl -0- meta

A-1305 CI H S-allyl O-benzyl -0- meta

A-1306 Br H S-allyl O-benzyl -0- meta

A-1307 OH H S-allyl O-benzyl -0- meta

A-1308 NH2 H S-allyl O-benzyl -0- meta

A-1309 N(CH₃)₂ H S-allyl O-benzyl -0- meta

A-1310 CH₃ CH₃ S-allyl O-benzyl -0- meta

A-131 1 CH2CH3 CH2CH3 S-allyl O-benzyl -0- meta

A-1312 =CH₂ S-allyl O-benzyl -0- meta

A-1313 cyclopropyl S-allyl O-benzyl -0- meta

A-1314 cyclobutyl S-allyl O-benzyl -0- meta

A-1315 cyclopentyl S-allyl O-benzyl -0- meta

A-1316 cyclohexyl S-allyl O-benzyl -0- meta

A-1317 1 -triazolyl H S-allyl O-benzyl -0- meta

A-1318 2-pyridinyl H S-allyl O-benzyl -0- meta

Line R¹ R² D X Y Pos.

A-1355 OH H H CN direct bond para

A-1356 NH₂ H H CN direct bond para

A-1357 N(CH₃)₂ H H CN direct bond para

A-1358 CHs CH₃ H CN direct bond para

A-1359 CH2CH3 CH2CH3 H CN direct bond para

A-1360 =CH₂ H CN direct bond para

A-1361 cyclopropyl H CN direct bond para

A-1362 cyclobutyl H CN direct bond para

A-1363 cyclopentyl H CN direct bond para

A-1364 cyclohexyl H CN direct bond para

A-1365 1 -triazolyl H H CN direct bond para

A-1366 2-pyridinyl H H CN direct bond para

A-1367 3-pyridinyl H H CN direct bond para

A-1368 4-pyridinyl H H CN direct bond para

A-1369 CHs H SH CN direct bond para

A-1370 CH2CH3 H SH CN direct bond para

A-1371 CH2CH2CH3 H SH CN direct bond para

A-1372 CH(CH₃)₂ H SH CN direct bond para

A-1373 OCH3 H SH CN direct bond para

A-1374 OCH2CH3 H SH CN direct bond para

A-1375 OCH(CH₃)₂ H SH CN direct bond para

A-1376 F H SH CN direct bond para

A-1377 CI H SH CN direct bond para

A-1378 Br H SH CN direct bond para

A-1379 OH H SH CN direct bond para

A-1380 NH2 H SH CN direct bond para

A-1381 N(CH₃)₂ H SH CN direct bond para

A-1382 CH₃ CH₃ SH CN direct bond para

A-1383 CH2CH3 CH2CH3 SH CN direct bond para

A-1384 =CH₂ SH CN direct bond para

A-1385 cyclopropyl SH CN direct bond para

A-1386 cyclobutyl SH CN direct bond para

A-1387 cyclopentyl SH CN direct bond para

A-1388 cyclohexyl SH CN direct bond para

A-1389 1 -triazolyl H SH CN direct bond para

A-1390 2-pyridinyl H SH CN direct bond para

Line R¹ R² D X Y Pos.

A-1535 3-pyridinyl H SCN OH direct bond para

A-1536 4-pyridinyl H SCN OH direct bond para

A-1537 CHs H H methoxy direct bond para

A-1538 CH2CH3 H H methoxy direct bond para

A-1539 CH2CH2CH3 H H methoxy direct bond para

A-1540 CH(CH₃)₂ H H methoxy direct bond para

A-1541 OCH3 H H methoxy direct bond para

A-1542 OCH2CH3 H H methoxy direct bond para

A-1543 OCH(CH₃)₂ H H methoxy direct bond para

A-1544 F H H methoxy direct bond para

A-1545 CI H H methoxy direct bond para

A-1546 Br H H methoxy direct bond para

A-1547 OH H H methoxy direct bond para

A-1548 NH2 H H methoxy direct bond para

A-1549 N(CH₃)₂ H H methoxy direct bond para

A-1550 CH₃ CH₃ H methoxy direct bond para

A-1551 CH₂CH₃ CH₂CH₃ H methoxy direct bond para

A-1552 =CH₂ H methoxy direct bond para

A-1553 cyclopropyl H methoxy direct bond para

A- 1554 cyclobutyl H methoxy direct bond para

A-1555 cyclopentyl H methoxy direct bond para

A-1556 cyclohexyl H methoxy direct bond para

A- 1557 1 -triazolyl H H methoxy direct bond para

A-1558 2-pyridinyl H H methoxy direct bond para

A-1559 3-pyridinyl H H methoxy direct bond para

A-1560 4-pyridinyl H H methoxy direct bond para

A-1561 CH₃ H SH methoxy direct bond para

A-1562 CH₂CH₃ H SH methoxy direct bond para

A-1563 CH2CH2CH₃ H SH methoxy direct bond para

A-1564 CH(CH₃)₂ H SH methoxy direct bond para

A-1565 OCH₃ H SH methoxy direct bond para

A-1566 OCH₂CH₃ H SH methoxy direct bond para

A-1567 OCH(CH₃)₂ H SH methoxy direct bond para

A-1568 F H SH methoxy direct bond para

A-1569 CI H SH methoxy direct bond para

A-1570 Br H SH methoxy direct bond para Line R¹ R² D X Y Pos.

A-1571 OH H SH methoxy direct bond para

A-1572 NH₂ H SH methoxy direct bond para

A-1573 N(CH₃)₂ H SH methoxy direct bond para

A-1574 CHs CH₃ SH methoxy direct bond para

A- 1575 CH2CH3 CH2CH3 SH methoxy direct bond para

A-1576 =CH₂ SH methoxy direct bond para

A- 1577 cyclopropyl SH methoxy direct bond para

A-1578 cyclobutyl SH methoxy direct bond para

A-1579 cyclopentyl SH methoxy direct bond para

A-1580 cyclohexyl SH methoxy direct bond para

A-1581 1 -triazolyl H SH methoxy direct bond para

A-1582 2-pyridinyl H SH methoxy direct bond para

A-1583 3-pyridinyl H SH methoxy direct bond para

A-1584 4-pyridinyl H SH methoxy direct bond para

A-1585 CHs H S-allyl methoxy direct bond para

A-1586 CH2CH3 H S-allyl methoxy direct bond para

A-1587 CH2CH2CH3 H S-allyl methoxy direct bond para

A-1588 CH(CH₃)₂ H S-allyl methoxy direct bond para

A-1589 OCH3 H S-allyl methoxy direct bond para

A-1590 OCH2CH3 H S-allyl methoxy direct bond para

A-1591 OCH(CH₃)₂ H S-allyl methoxy direct bond para

A-1592 F H S-allyl methoxy direct bond para

A-1593 CI H S-allyl methoxy direct bond para

A-1594 Br H S-allyl methoxy direct bond para

A-1595 OH H S-allyl methoxy direct bond para

A-1596 NH2 H S-allyl methoxy direct bond para

A-1597 N(CH₃)₂ H S-allyl methoxy direct bond para

A-1598 CH₃ CH₃ S-allyl methoxy direct bond para

A-1599 CH2CH3 CH2CH3 S-allyl methoxy direct bond para

A-1600 =CH₂ S-allyl methoxy direct bond para

A-1601 cyclopropyl S-allyl methoxy direct bond para

A-1602 cyclobutyl S-allyl methoxy direct bond para

A-1603 cyclopentyl S-allyl methoxy direct bond para

A-1604 cyclohexyl S-allyl methoxy direct bond para

A-1605 1 -triazolyl H S-allyl methoxy direct bond para

A-1606 2-pyridinyl H S-allyl methoxy direct bond para Line R¹ R² D X Y Pos.

A-1607 3-pyridinyl H S-allyl methoxy direct bond para

A-1608 4-pyridinyl H S-allyl methoxy direct bond para

A-1609 CHs H SCN methoxy direct bond para

A-1610 CH2CH3 H SCN methoxy direct bond para

A-161 1 CH2CH2CH3 H SCN methoxy direct bond para

A-1612 CH(CH₃)₂ H SCN methoxy direct bond para

A-1613 OCH3 H SCN methoxy direct bond para

A-1614 OCH2CH3 H SCN methoxy direct bond para

A-1615 OCH(CH₃)₂ H SCN methoxy direct bond para

A-1616 F H SCN methoxy direct bond para

A-1617 CI H SCN methoxy direct bond para

A-1618 Br H SCN methoxy direct bond para

A-1619 OH H SCN methoxy direct bond para

A-1620 NH2 H SCN methoxy direct bond para

A-1621 N(CH₃)₂ H SCN methoxy direct bond para

A-1622 CH₃ CH₃ SCN methoxy direct bond para

A-1623 CH₂CH₃ CH₂CH₃ SCN methoxy direct bond para

A-1624 =CH₂ SCN methoxy direct bond para

A-1625 cyclopropyl SCN methoxy direct bond para

A-1626 cyclobutyl SCN methoxy direct bond para

A-1627 cyclopentyl SCN methoxy direct bond para

A-1628 cyclohexyl SCN methoxy direct bond para

A-1629 1 -triazolyl H SCN methoxy direct bond para

A-1630 2-pyridinyl H SCN methoxy direct bond para

A-1631 3-pyridinyl H SCN methoxy direct bond para

A-1632 4-pyridinyl H SCN methoxy direct bond para

A-1633 CH₃ H H ethoxy direct bond para

A-1634 CH₂CH₃ H H ethoxy direct bond para

A-1635 CH2CH2CH₃ H H ethoxy direct bond para

A-1636 CH(CH₃)₂ H H ethoxy direct bond para

A-1637 OCH₃ H H ethoxy direct bond para

A-1638 OCH₂CH₃ H H ethoxy direct bond para

A-1639 OCH(CH₃)₂ H H ethoxy direct bond para

A-1640 F H H ethoxy direct bond para

A-1641 CI H H ethoxy direct bond para

A-1642 Br H H ethoxy direct bond para

Line R¹ R² D X Y Pos.

A-1679 3-pyridinyl H SH ethoxy direct bond para

A-1680 4-pyridinyl H SH ethoxy direct bond para

A-1681 CHs H S-allyl ethoxy direct bond para

A-1682 CH2CH3 H S-allyl ethoxy direct bond para

A-1683 CH2CH2CH3 H S-allyl ethoxy direct bond para

A-1684 CH(CH₃)₂ H S-allyl ethoxy direct bond para

A-1685 OCH3 H S-allyl ethoxy direct bond para

A-1686 OCH2CH3 H S-allyl ethoxy direct bond para

A-1687 OCH(CH₃)₂ H S-allyl ethoxy direct bond para

A-1688 F H S-allyl ethoxy direct bond para

A-1689 CI H S-allyl ethoxy direct bond para

A-1690 Br H S-allyl ethoxy direct bond para

A-1691 OH H S-allyl ethoxy direct bond para

A-1692 NH2 H S-allyl ethoxy direct bond para

A-1693 N(CH₃)₂ H S-allyl ethoxy direct bond para

A-1694 CH₃ CH₃ S-allyl ethoxy direct bond para

A-1695 CH₂CH₃ CH₂CH₃ S-allyl ethoxy direct bond para

A-1696 =CH₂ S-allyl ethoxy direct bond para

A-1697 cyclopropyl S-allyl ethoxy direct bond para

A-1698 cyclobutyl S-allyl ethoxy direct bond para

A-1699 cyclopentyl S-allyl ethoxy direct bond para

A-1700 cyclohexyl S-allyl ethoxy direct bond para

A-1701 1 -triazolyl H S-allyl ethoxy direct bond para

A-1702 2-pyridinyl H S-allyl ethoxy direct bond para

A-1703 3-pyridinyl H S-allyl ethoxy direct bond para

A-1704 4-pyridinyl H S-allyl ethoxy direct bond para

A-1705 CH₃ H SCN ethoxy direct bond para

A-1706 CH₂CH₃ H SCN ethoxy direct bond para

A-1707 CH2CH2CH₃ H SCN ethoxy direct bond para

A-1708 CH(CH₃)₂ H SCN ethoxy direct bond para

A-1709 OCH₃ H SCN ethoxy direct bond para

A-1710 OCH₂CH₃ H SCN ethoxy direct bond para

A-171 1 OCH(CH₃)₂ H SCN ethoxy direct bond para

A-1712 F H SCN ethoxy direct bond para

A-1713 CI H SCN ethoxy direct bond para

A-1714 Br H SCN ethoxy direct bond para

Line R¹ R² D X Y Pos.

A-1751 3-pyridinyl H H O-allyl direct bond para

A-1752 4-pyridinyl H H O-allyl direct bond para

A-1753 CHs H SH O-allyl direct bond para

A-1754 CH2CH3 H SH O-allyl direct bond para

A- 1755 CH2CH2CH3 H SH O-allyl direct bond para

A-1756 CH(CH₃)₂ H SH O-allyl direct bond para

A- 1757 OCH3 H SH O-allyl direct bond para

A-1758 OCH2CH3 H SH O-allyl direct bond para

A-1759 OCH(CH₃)₂ H SH O-allyl direct bond para

A-1760 F H SH O-allyl direct bond para

A-1761 CI H SH O-allyl direct bond para

A-1762 Br H SH O-allyl direct bond para

A-1763 OH H SH O-allyl direct bond para

A-1764 NH2 H SH O-allyl direct bond para

A-1765 N(CH₃)₂ H SH O-allyl direct bond para

A-1766 CH₃ CH₃ SH O-allyl direct bond para

A-1767 CH₂CH₃ CH₂CH₃ SH O-allyl direct bond para

A-1768 =CH₂ SH O-allyl direct bond para

A-1769 cyclopropyl SH O-allyl direct bond para

A-1770 cyclobutyl SH O-allyl direct bond para

A-1771 cyclopentyl SH O-allyl direct bond para

A-1772 cyclohexyl SH O-allyl direct bond para

A-1773 1 -triazolyl H SH O-allyl direct bond para

A-1774 2-pyridinyl H SH O-allyl direct bond para

A- 1775 3-pyridinyl H SH O-allyl direct bond para

A-1776 4-pyridinyl H SH O-allyl direct bond para

A- 1777 CH₃ H S-allyl O-allyl direct bond para

A-1778 CH₂CH₃ H S-allyl O-allyl direct bond para

A-1779 CH2CH2CH₃ H S-allyl O-allyl direct bond para

A-1780 CH(CH₃)₂ H S-allyl O-allyl direct bond para

A-1781 OCH₃ H S-allyl O-allyl direct bond para

A-1782 OCH₂CH₃ H S-allyl O-allyl direct bond para

A-1783 OCH(CH₃)₂ H S-allyl O-allyl direct bond para

A-1784 F H S-allyl O-allyl direct bond para

A-1785 CI H S-allyl O-allyl direct bond para

A-1786 Br H S-allyl O-allyl direct bond para

Line R¹ R² D X Y Pos.

A-2003 OH H SCN O-benzyl direct bond para

A-2004 NH₂ H SCN O-benzyl direct bond para

A-2005 N(CH₃)₂ H SCN O-benzyl direct bond para

A-2006 CHs CH₃ SCN O-benzyl direct bond para

A-2007 CH2CH3 CH2CH3 SCN O-benzyl direct bond para

A-2008 =CH₂ SCN O-benzyl direct bond para

A-2009 cyclopropyl SCN O-benzyl direct bond para

A-2010 cyclobutyl SCN O-benzyl direct bond para

A-201 1 cyclopentyl SCN O-benzyl direct bond para

A-2012 cyclohexyl SCN O-benzyl direct bond para

A-2013 1 -triazolyl H SCN O-benzyl direct bond para

A-2014 2-pyridinyl H SCN O-benzyl direct bond para

A-2015 3-pyridinyl H SCN O-benzyl direct bond para

A-2016 4-pyridinyl H SCN O-benzyl direct bond para

A-2017 CHs H H CN direct bond meta

A-2018 CH2CH3 H H CN direct bond meta

A-2019 CH2CH2CH3 H H CN direct bond meta

A-2020 CH(CH₃)₂ H H CN direct bond meta

A-2021 OCH3 H H CN direct bond meta

A-2022 OCH2CH3 H H CN direct bond meta

A-2023 OCH(CH₃)₂ H H CN direct bond meta

A-2024 F H H CN direct bond meta

A-2025 CI H H CN direct bond meta

A-2026 Br H H CN direct bond meta

A-2027 OH H H CN direct bond meta

A-2028 NH2 H H CN direct bond meta

A-2029 N(CH₃)₂ H H CN direct bond meta

A-2030 CH₃ CH₃ H CN direct bond meta

A-2031 CH2CH3 CH2CH3 H CN direct bond meta

A-2032 =CH₂ H CN direct bond meta

A-2033 cyclopropyl H CN direct bond meta

A-2034 cyclobutyl H CN direct bond meta

A-2035 cyclopentyl H CN direct bond meta

A-2036 cyclohexyl H CN direct bond meta

A-2037 1 -triazolyl H H CN direct bond meta

A-2038 2-pyridinyl H H CN direct bond meta

Line R¹ R² D X Y Pos.

A-2075 OH H S-allyl CN direct bond meta

A-2076 NH₂ H S-allyl CN direct bond meta

A-2077 N(CH₃)₂ H S-allyl CN direct bond meta

A-2078 CHs CH₃ S-allyl CN direct bond meta

A-2079 CH2CH3 CH2CH3 S-allyl CN direct bond meta

A-2080 =CH₂ S-allyl CN direct bond meta

A-2081 cyclopropyl S-allyl CN direct bond meta

A-2082 cyclobutyl S-allyl CN direct bond meta

A-2083 cyclopentyl S-allyl CN direct bond meta

A-2084 cyclohexyl S-allyl CN direct bond meta

A-2085 1 -triazolyl H S-allyl CN direct bond meta

A-2086 2-pyridinyl H S-allyl CN direct bond meta

A-2087 3-pyridinyl H S-allyl CN direct bond meta

A-2088 4-pyridinyl H S-allyl CN direct bond meta

A-2089 CHs H SCN CN direct bond meta

A-2090 CH2CH3 H SCN CN direct bond meta

A-2091 CH2CH2CH3 H SCN CN direct bond meta

A-2092 CH(CH₃)₂ H SCN CN direct bond meta

A-2093 OCH3 H SCN CN direct bond meta

A-2094 OCH2CH3 H SCN CN direct bond meta

A-2095 OCH(CH₃)₂ H SCN CN direct bond meta

A-2096 F H SCN CN direct bond meta

A-2097 CI H SCN CN direct bond meta

A-2098 Br H SCN CN direct bond meta

A-2099 OH H SCN CN direct bond meta

A-2100 NH2 H SCN CN direct bond meta

A-2101 N(CH₃)₂ H SCN CN direct bond meta

A-2102 CH₃ CH₃ SCN CN direct bond meta

A-2103 CH2CH3 CH2CH3 SCN CN direct bond meta

A-2104 =CH₂ SCN CN direct bond meta

A-2105 cyclopropyl SCN CN direct bond meta

A-2106 cyclobutyl SCN CN direct bond meta

A-2107 cyclopentyl SCN CN direct bond meta

A-2108 cyclohexyl SCN CN direct bond meta

A-2109 1 -triazolyl H SCN CN direct bond meta

A-21 10 2-pyridinyl H SCN CN direct bond meta

Line R¹ R² D X Y Pos.

A-2255 3-pyridinyl H SH methoxy direct bond meta

A-2256 4-pyridinyl H SH methoxy direct bond meta

A-2257 CHs H S-allyl methoxy direct bond meta

A-2258 CH2CH3 H S-allyl methoxy direct bond meta

A-2259 CH2CH2CH3 H S-allyl methoxy direct bond meta

A-2260 CH(CH₃)₂ H S-allyl methoxy direct bond meta

A-2261 OCH3 H S-allyl methoxy direct bond meta

A-2262 OCH2CH3 H S-allyl methoxy direct bond meta

A-2263 OCH(CH₃)₂ H S-allyl methoxy direct bond meta

A-2264 F H S-allyl methoxy direct bond meta

A-2265 CI H S-allyl methoxy direct bond meta

A-2266 Br H S-allyl methoxy direct bond meta

A-2267 OH H S-allyl methoxy direct bond meta

A-2268 NH2 H S-allyl methoxy direct bond meta

A-2269 N(CH₃)₂ H S-allyl methoxy direct bond meta

A-2270 CH₃ CH₃ S-allyl methoxy direct bond meta

A-2271 CH₂CH₃ CH₂CH₃ S-allyl methoxy direct bond meta

A-2272 =CH₂ S-allyl methoxy direct bond meta

A-2273 cyclopropyl S-allyl methoxy direct bond meta

A-2274 cyclobutyl S-allyl methoxy direct bond meta

A-2275 cyclopentyl S-allyl methoxy direct bond meta

A-2276 cyclohexyl S-allyl methoxy direct bond meta

A-2277 1 -triazolyl H S-allyl methoxy direct bond meta

A-2278 2-pyridinyl H S-allyl methoxy direct bond meta

A-2279 3-pyridinyl H S-allyl methoxy direct bond meta

A-2280 4-pyridinyl H S-allyl methoxy direct bond meta

A-2281 CH₃ H SCN methoxy direct bond meta

A-2282 CH₂CH₃ H SCN methoxy direct bond meta

A-2283 CH2CH2CH₃ H SCN methoxy direct bond meta

A-2284 CH(CH₃)₂ H SCN methoxy direct bond meta

A-2285 OCH₃ H SCN methoxy direct bond meta

A-2286 OCH₂CH₃ H SCN methoxy direct bond meta

A-2287 OCH(CH₃)₂ H SCN methoxy direct bond meta

A-2288 F H SCN methoxy direct bond meta

A-2289 CI H SCN methoxy direct bond meta

A-2290 Br H SCN methoxy direct bond meta Line R¹ R² D X Y Pos.

A-2291 OH H SCN methoxy direct bond meta

A-2292 NH₂ H SCN methoxy direct bond meta

A-2293 N(CH₃)₂ H SCN methoxy direct bond meta

A-2294 CHs CH₃ SCN methoxy direct bond meta

A-2295 CH2CH3 CH2CH3 SCN methoxy direct bond meta

A-2296 =CH₂ SCN methoxy direct bond meta

A-2297 cyclopropyl SCN methoxy direct bond meta

A-2298 cyclobutyl SCN methoxy direct bond meta

A-2299 cyclopentyl SCN methoxy direct bond meta

A-2300 cyclohexyl SCN methoxy direct bond meta

A-2301 1 -triazolyl H SCN methoxy direct bond meta

A-2302 2-pyridinyl H SCN methoxy direct bond meta

A-2303 3-pyridinyl H SCN methoxy direct bond meta

A-2304 4-pyridinyl H SCN methoxy direct bond meta

A-2305 CHs H H ethoxy direct bond meta

A-2306 CH2CH3 H H ethoxy direct bond meta

A-2307 CH2CH2CH3 H H ethoxy direct bond meta

A-2308 CH(CH₃)₂ H H ethoxy direct bond meta

A-2309 OCH3 H H ethoxy direct bond meta

A-2310 OCH2CH3 H H ethoxy direct bond meta

A-231 1 OCH(CH₃)₂ H H ethoxy direct bond meta

A-2312 F H H ethoxy direct bond meta

A-2313 CI H H ethoxy direct bond meta

A-2314 Br H H ethoxy direct bond meta

A-2315 OH H H ethoxy direct bond meta

A-2316 NH2 H H ethoxy direct bond meta

A-2317 N(CH₃)₂ H H ethoxy direct bond meta

A-2318 CH₃ CH₃ H ethoxy direct bond meta

A-2319 CH2CH3 CH2CH3 H ethoxy direct bond meta

A-2320 =CH₂ H ethoxy direct bond meta

A-2321 cyclopropyl H ethoxy direct bond meta

A-2322 cyclobutyl H ethoxy direct bond meta

A-2323 cyclopentyl H ethoxy direct bond meta

A-2324 cyclohexyl H ethoxy direct bond meta

A-2325 1 -triazolyl H H ethoxy direct bond meta

A-2326 2-pyridinyl H H ethoxy direct bond meta Line R¹ R² D X Y Pos.

A-2327 3-pyridinyl H H ethoxy direct bond meta

A-2328 4-pyridinyl H H ethoxy direct bond meta

A-2329 CHs H SH ethoxy direct bond meta

A-2330 CH2CH3 H SH ethoxy direct bond meta

A-2331 CH2CH2CH3 H SH ethoxy direct bond meta

A-2332 CH(CH₃)₂ H SH ethoxy direct bond meta

A-2333 OCH3 H SH ethoxy direct bond meta

A-2334 OCH2CH3 H SH ethoxy direct bond meta

A-2335 OCH(CH₃)₂ H SH ethoxy direct bond meta

A-2336 F H SH ethoxy direct bond meta

A-2337 CI H SH ethoxy direct bond meta

A-2338 Br H SH ethoxy direct bond meta

A-2339 OH H SH ethoxy direct bond meta

A-2340 NH2 H SH ethoxy direct bond meta

A-2341 N(CH₃)₂ H SH ethoxy direct bond meta

A-2342 CH₃ CH₃ SH ethoxy direct bond meta

A-2343 CH₂CH₃ CH₂CH₃ SH ethoxy direct bond meta

A-2344 =CH₂ SH ethoxy direct bond meta

A-2345 cyclopropyl SH ethoxy direct bond meta

A-2346 cyclobutyl SH ethoxy direct bond meta

A-2347 cyclopentyl SH ethoxy direct bond meta

A-2348 cyclohexyl SH ethoxy direct bond meta

A-2349 1 -triazolyl H SH ethoxy direct bond meta

A-2350 2-pyridinyl H SH ethoxy direct bond meta

A-2351 3-pyridinyl H SH ethoxy direct bond meta

A-2352 4-pyridinyl H SH ethoxy direct bond meta

A-2353 CH₃ H S-allyl ethoxy direct bond meta

A-2354 CH₂CH₃ H S-allyl ethoxy direct bond meta

A-2355 CH2CH2CH₃ H S-allyl ethoxy direct bond meta

A-2356 CH(CH₃)₂ H S-allyl ethoxy direct bond meta

A-2357 OCH₃ H S-allyl ethoxy direct bond meta

A-2358 OCH₂CH₃ H S-allyl ethoxy direct bond meta

A-2359 OCH(CH₃)₂ H S-allyl ethoxy direct bond meta

A-2360 F H S-allyl ethoxy direct bond meta

A-2361 CI H S-allyl ethoxy direct bond meta

A-2362 Br H S-allyl ethoxy direct bond meta

Line R¹ R² D X Y Pos.

A-2399 3-pyridinyl H SCN ethoxy direct bond meta

A-2400 4-pyridinyl H SCN ethoxy direct bond meta

A-2401 CHs H H O-allyl direct bond meta

A-2402 CH2CH3 H H O-allyl direct bond meta

A-2403 CH2CH2CH3 H H O-allyl direct bond meta

A-2404 CH(CH₃)₂ H H O-allyl direct bond meta

A-2405 OCH3 H H O-allyl direct bond meta

A-2406 OCH2CH3 H H O-allyl direct bond meta

A-2407 OCH(CH₃)₂ H H O-allyl direct bond meta

A-2408 F H H O-allyl direct bond meta

A-2409 CI H H O-allyl direct bond meta

A-2410 Br H H O-allyl direct bond meta

A-241 1 OH H H O-allyl direct bond meta

A-2412 NH2 H H O-allyl direct bond meta

A-2413 N(CH₃)₂ H H O-allyl direct bond meta

A-2414 CH₃ CH₃ H O-allyl direct bond meta

A-2415 CH₂CH₃ CH₂CH₃ H O-allyl direct bond meta

A-2416 =CH₂ H O-allyl direct bond meta

A-2417 cyclopropyl H O-allyl direct bond meta

A-2418 cyclobutyl H O-allyl direct bond meta

A-2419 cyclopentyl H O-allyl direct bond meta

A-2420 cyclohexyl H O-allyl direct bond meta

A-2421 1 -triazolyl H H O-allyl direct bond meta

A-2422 2-pyridinyl H H O-allyl direct bond meta

A-2423 3-pyridinyl H H O-allyl direct bond meta

A-2424 4-pyridinyl H H O-allyl direct bond meta

A-2425 CH₃ H SH O-allyl direct bond meta

A-2426 CH₂CH₃ H SH O-allyl direct bond meta

A-2427 CH2CH2CH₃ H SH O-allyl direct bond meta

A-2428 CH(CH₃)₂ H SH O-allyl direct bond meta

A-2429 OCH₃ H SH O-allyl direct bond meta

A-2430 OCH₂CH₃ H SH O-allyl direct bond meta

A-2431 OCH(CH₃)₂ H SH O-allyl direct bond meta

A-2432 F H SH O-allyl direct bond meta

A-2433 CI H SH O-allyl direct bond meta

A-2434 Br H SH O-allyl direct bond meta

Line R¹ R² D X Y Pos.

A-2471 3-pyridinyl H S-allyl O-allyl direct bond meta

A-2472 4-pyridinyl H S-allyl O-allyl direct bond meta

A-2473 CHs H SCN O-allyl direct bond meta

A-2474 CH2CH3 H SCN O-allyl direct bond meta

A-2475 CH2CH2CH3 H SCN O-allyl direct bond meta

A-2476 CH(CH₃)₂ H SCN O-allyl direct bond meta

A-2477 OCH3 H SCN O-allyl direct bond meta

A-2478 OCH2CH3 H SCN O-allyl direct bond meta

A-2479 OCH(CH₃)₂ H SCN O-allyl direct bond meta

A-2480 F H SCN O-allyl direct bond meta

A-2481 CI H SCN O-allyl direct bond meta

A-2482 Br H SCN O-allyl direct bond meta

A-2483 OH H SCN O-allyl direct bond meta

A-2484 NH2 H SCN O-allyl direct bond meta

A-2485 N(CH₃)₂ H SCN O-allyl direct bond meta

A-2486 CH₃ CH₃ SCN O-allyl direct bond meta

A-2487 CH₂CH₃ CH₂CH₃ SCN O-allyl direct bond meta

A-2488 =CH₂ SCN O-allyl direct bond meta

A-2489 cyclopropyl SCN O-allyl direct bond meta

A-2490 cyclobutyl SCN O-allyl direct bond meta

A-2491 cyclopentyl SCN O-allyl direct bond meta

A-2492 cyclohexyl SCN O-allyl direct bond meta

A-2493 1 -triazolyl H SCN O-allyl direct bond meta

A-2494 2-pyridinyl H SCN O-allyl direct bond meta

A-2495 3-pyridinyl H SCN O-allyl direct bond meta

A-2496 4-pyridinyl H SCN O-allyl direct bond meta

A-2497 CH₃ H H O-propargyl direct bond meta

A-2498 CH₂CH₃ H H O-propargyl direct bond meta

A-2499 CH2CH2CH₃ H H O-propargyl direct bond meta

A-2500 CH(CH₃)₂ H H O-propargyl direct bond meta

A-2501 OCH₃ H H O-propargyl direct bond meta

A-2502 OCH₂CH₃ H H O-propargyl direct bond meta

A-2503 OCH(CH₃)₂ H H O-propargyl direct bond meta

A-2504 F H H O-propargyl direct bond meta

A-2505 CI H H O-propargyl direct bond meta

A-2506 Br H H O-propargyl direct bond meta

A-2688 4-pyridinyl H SCN O-benzyl direct bond meta

Further preferred embodiments relate to compounds I wherein (R⁴)_n in each case has one of the following meanings as defined in lines B-1 to B-77 in table B.

Table B:

line (R⁴)n line (R⁴)n

B-1 2-F B-34 2,4-F₂

B-2 3-F B-35 2,3-F₂

B-3 4-F B-36 2,5-F₂

B-4 2-CI B-37 2,6-F₂

B-5 3-CI B-38 3,4-F₂

B-6 4-CI B-39 3,5-F₂

B-7 2-Br B-40 2,4-CI₂

B-8 3-Br B-41 2,3-CI₂

B-9 4-Br B-42 2,5-CI₂

B-10 2-I B-43 2,6-CI₂

B-1 1 3-I B-44 3,4-CI₂

B-12 4-I B-45 3,5-CI₂

B-13 2-CHs B-46 2,4-(CH₃₎2

B-14 3-CHs B-47 2,3-(CH₃)₂

B-15 4-CHs B-48 2,5-(CH₃)₂

B-16 2-OCHs B-49 2,6-(CH₃)₂

B-17 3-OCHs B-50 3,4-(CH₃)₂

B-18 4-OCHs B-51 3,5-(CH₃)₂

B-19 2-CFs B-52 2,4-(CF₃)₂

B-20 3-CFs B-53 2,3-(CF₃)₂

B-21 4-CFs B-54 2,5-(CF₃)₂

B-22 2-CHF₂ B-55 2,6-(CF₃)₂

B-23 3-CHF2 B-56 3,4-(CF₃)₂

B-24 4-CHF2 B-57 3,5-(CF₃)₂

B-25 2-SCHs B-58 2,4-CHF₂

B-26 3-SCHs B-59 2-F-4-CI

B-27 4-SCHs B-60 2-F-4-CF3

B-28 2-S(=0)CH₃ B-61 2-F-4-CHF2

B-29 3-S(=0)CH₃ B-62 2-CI-4-F

B-30 4-S(=0)CH₃ B-63 2-CI-4-CF3

B-31 2-SO2CH3 B-64 2-CI-4-CHF2

B-32 3-SO2CH3 B-65 2-CF3-4-F

B-33 4-SO2CH3 B-66 2-CF3-4-CI line (R⁴)n line (R⁴)n

B-67 2-CF3-4-CHF2 B-73 4-CN

B-68 2-CHF2-4-F B-74 2-F-4-CN

B-69 2-CHF2-4-CI B-75 2-CI-4-CN

B-70 2-CHF2-4-CF3 B-76 2-CF3-4-CN

B-71 2-CN B-77 2-CHF2-4-CN

B-72 3-CN

According to further preferred embodiments of the invention Z is a phenyl ring which is substituted by one or more radicals R^L as defined in lines C-1 to C-17 in table C. The radicals R^L in Table C are to be construed in positions relative to the group Y.

Table C:

In still further preferred embodiments of the invention the group Z in each case is one of the following as defined in lines Z-1 to Z-1 1 in table Z, wherein # indicates the point of attachment of the group Y:

Table Z:

Further embodiments of the invention relate to compounds I, wherein the combination of the groups A, R⁵, R⁶ and R⁷ are as specified in compounds of the formulae I.A, I.B, I.C, I

With respect to their use, particular preference is given to the compounds compiled in the Tables 1 to 1288 below, wherein the meaning of the combination of substituents R¹, R², X, D, Y and the position of group Y on the phenyl ring are selected from line A-1 to A-2688 in Table A; and wherein the meaning of the group R⁴ and n are selected from line B-1 to B-77 as described in Table B; and wherein the meaning of the group R^L is selected from lines C-1 to C-17 in Table C; and wherein the meaning of Z is phenyl or is selected from lines Z-1 to Z-1 1 in Table Z.

Table 1 : Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B (compounds I. A.a1.b1 to I.A.a672.b1 ).

Table 2: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-2 in Table B (compounds I. A.a1.b2 to I.A.a672.b2).

Table 3: Compounds I.A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-3 in Table B (compounds I. A.a1.b3 to I.A.a672.b3).

Table 4: Compounds I.A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B (compounds I. A.a1.b4 to I.A.a672.b4).

Table 5: Compounds I.A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-5 in Table B (compounds I. A.a1.b5 to I.A.a672.b5).

Table 6: Compounds I.A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-6 in Table B (compounds I. A.a1.b6 to I.A.a672.b6).

Table 7: Compounds I.A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-7 in Table B (compounds I. A.a1.b7 to I.A.a672.b7).

Table 8: Compounds I.A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-8 in Table B (compounds I. A.a1.b8 to I.A.a672.b8).

Table 9: Compounds I.A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-9 in Table B (compounds I. A.a1.b9 to I.A.a672.b9).

Table 10: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-10 in Table B (compounds I. A.a1.b10 to I.A.a672.b10).

Table 1 1 : Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 1 in Table B (compounds I. A.a1.b1 1 to I.A.a672.b1 1 ).

Table 12: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-12 in Table B (compounds I. A.a1.b12 to I.A.a672.b12).

Table 13: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-13 in Table B (compounds I. A.a1.b13 to I.A.a672.b13).

Table 14: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-14 in Table B (compounds I. A.a1.b14 to I.A.a672.b14).

Table 15: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-15 in Table B (compounds I. A.a1.b15 to I.A.a672.b15).

Table 16: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-16 in Table B (compounds I. A.a1.b16 to l.A.a672.b16).

Table 17: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-17 in Table B (compounds I. A.a1.b17 to I.A.a672.b17).

Table 18: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-18 in Table B (compounds I. A.a1.b18 to I.A.a672.b18).

Table 19: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B (compounds I. A.a1.b19 to I.A.a672.b19). Table 20: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-20 in Table B (compounds I. A.a1.b20 to I.A.a672.b20).

Table 21 : Compounds I.A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-21 in Table B (compounds I. A.a1.b21 to I.A.a672.b21 ).

Table 22: Compounds I.A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-22 in Table B (compounds I. A.a1.b22 to I.A.a672.b22).

Table 23: Compounds I.A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-23 in Table B (compounds I. A.a1.b23 to I.A.a672.b23).

Table 24: Compounds I.A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-24 in Table B (compounds I. A.a1.b24 to I.A.a672.b24).

Table 25: Compounds I.A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-25 in Table B (compounds I. A.a1.b25 to I.A.a672.b25).

Table 26: Compounds I.A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-26 in Table B (compounds I. A.a1.b26 to I.A.a672.b26).

Table 27: Compounds I.A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-27 in Table B (compounds I. A.a1.b27 to I.A.a672.b27).

Table 28: Compounds I.A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-28 in Table B (compounds I. A.a1.b28 to I.A.a672.b28).

Table 29: Compounds I.A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-29 in Table B (compounds I. A.a1.b29 to I.A.a672.b29).

Table 30: Compounds I.A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-30 in Table B (compounds I. A.a1.b30 to I.A.a672.b30).

Table 31 : Compounds I .A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-31 in Table B (compounds I. A.a1.b31 to I.A.a672.b31 ).

Table 32: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-32 in Table B (compounds I. A.a1.b32 to I.A.a672.b32).

Table 33: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-33 in Table B (compounds I. A.a1 .b33 to I.A.a672.b33).

Table 34: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-34 in Table B (compounds I. A.a1.b34 to I.A.a672.b34).

Table 35: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-35 in Table B (compounds I. A.a1.b35 to I.A.a672.b35).

Table 36: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-36 in Table B (compounds I. A.a1.b36 to I.A.a672.b36).

Table 37: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-37 in Table B (compounds I. A.a1.b37 to I.A.a672.b37).

Table 38: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-38 in Table B (compounds I. A.a1.b38 to I.A.a672.b38).

Table 39: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-39 in Table B (compounds I. A.a1.b39 to I.A.a672.b39).

Table 40: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-40 in Table B (compounds I. A.a1.b40 to I.A.a672.b40). Table 41 : Compounds I .A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-41 in Table B (compounds I. A.a1.b41 to I.A.a672.b41 ).

Table 42: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-42 in Table B (compounds I. A.a1.b42 to I.A.a672.b42).

Table 43: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-43 in Table B (compounds I. A.a1.b43 to I.A.a672.b43).

Table 44: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-44 in Table B (compounds I. A.a1.b44 to I.A.a672.b44).

Table 45: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-45 in Table B (compounds I. A.a1.b45 to I.A.a672.b45).

Table 46: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-46 in Table B (compounds I. A.a1.b46 to I.A.a672.b46).

Table 47: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-47 in Table B (compounds I. A.a1.b47 to I.A.a672.b47).

Table 48: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-48 in Table B (compounds I. A.a1.b48 to I.A.a672.b48).

Table 49: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-49 in Table B (compounds I. A.a1.b49 to I.A.a672.b49).

Table 50: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-50 in Table B (compounds I. A.a1.b50 to I.A.a672.b50).

Table 51 : Compounds I .A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-51 in Table B (compounds I. A.a1.b51 to I.A.a672.b51 ).

Table 52: Compounds I .A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-52 in Table B (compounds I. A.a1.b52 to I.A.a672.b52).

Table 53: Compounds I .A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-53 in Table B (compounds I. A.a1.b53 to I.A.a672.b53).

Table 54: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-54 in Table B (compounds I. A.a1 .b54 to I.A.a672.b54).

Table 55: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-55 in Table B (compounds I. A.a1.b55 to I.A.a672.b55).

Table 56: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-56 in Table B (compounds I. A.a1.b56 to I.A.a672.b56).

Table 57: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-57 in Table B (compounds I. A.a1.b57 to I.A.a672.b57).

Table 58: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-58 in Table B (compounds I. A.a1.b58 to I.A.a672.b58).

Table 59: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-59 in Table B (compounds I. A.a1.b59 to I.A.a672.b59).

Table 60: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-60 in Table B (compounds I. A.a1.b60 to I.A.a672.b60).

Table 61 : Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-61 in Table B (compounds I. A.a1.b61 to I.A.a672.b61 ). Table 62: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-62 in Table B (compounds I. A.a1.b62 to I.A.a672.b62).

Table 63: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-63 in Table B (compounds I. A.a1.b63 to I.A.a672.b63).

Table 64: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-64 in Table B (compounds I. A.a1.b64 to I.A.a672.b64).

Table 65: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-65 in Table B (compounds I. A.a1.b65 to I.A.a672.b65).

Table 66: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-66 in Table B (compounds I. A.a1.b66 to I.A.a672.b66).

Table 67: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-67 in Table B (compounds I. A.a1.b67 to I.A.a672.b67).

Table 68: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-68 in Table B (compounds I. A.a1.b68 to I.A.a672.b68).

Table 69: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-69 in Table B (compounds I. A.a1.b69 to I.A.a672.b69).

Table 70: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-70 in Table B (compounds I. A.a1.b70 to I.A.a672.b70).

Table 71 : Compounds I.A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-71 in Table B (compounds I. A.a1.b71 to I.A.a672.b71 ).

Table 72: Compounds I.A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-72 in Table B (compounds I. A.a1.b72 to I.A.a672.b72).

Table 73: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-73 in Table B (compounds I. A.a1.b73 to I.A.a672.b73).

Table 74: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-74 in Table B (compounds I. A.a1.b74 to I.A.a672.b74).

Table 75: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-75 in Table B (compounds I. A.a1.b75 to I.A.a672.b75).

Table 76: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-76 in Table B (compounds I. A.a1.b76 to I.A.a672.b76).

Table 77: Compounds I. A , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-77 in Table B (compounds I. A.a1.b77 to I.A.a672.b77).

Table 78: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 of table C (compounds I.A.a1 .b1 .c1 to I.A.a2688.b1 .c1 ).

Table 79: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 of table C (compounds I.A.a1 .b4.c1 to I.A.a2688.b4.c1 ).

Table 80: Compounds I .A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 of table C (compounds I.A.a1 .b19.c1 to I.A.a2688.b19.c1 ).

Table 81 : Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-2 of table C (compounds I.A.a1 .b1 .c2 to I.A.a2688.b1 .c2). Table 82: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-2 of table C (compounds I.A.a1 .b4.c2 to I.A.a2688.b4.c2).

Table 83: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-2 of table C (compounds I.A.a1 .b19.c2 to I.A.a2688.b19.c2).

Table 84: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-3 of table C (compounds I.A.a1.b1 .c3 to I.A.a2688.b1 .c3).

Table 85: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-3 of table C (compounds I.A.a1 .b4.c3 to I.A.a2688.b4.c3).

Table 86: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-3 of table C (compounds I.A.a1 .b19.c3 to I.A.a2688.b19.c3).

Table 87: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-4 of table C (compounds I.A.a1 .b1 .c4 to I.A.a2688.b1 .c4).

Table 88: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-4 of table C (compounds I.A.a1 .b4.c4 to I.A.a2688.b4.c4).

Table 89: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-4 of table C (compounds I.A.a1 .b19.c4 to I.A.a2688.b19.c4).

Table 90: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-5 of table C (compounds I.A.a1 .b1 .c5 to I.A.a2688.b1 .c5).

Table 91 : Compounds I .A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-5 of table C (compounds I.A.a1 .b4.c5 to I.A.a2688.b4.c5).

Table 92: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-5 of table C (compounds I.A.a1 .b19.c5 to I.A.a2688.b19.c5).

Table 93: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-6 of table C (compounds I.A.a1 .b1 .c6 to I.A.a2688.b1 .c6).

Table 94: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-6 of table C (compounds I.A.a1 .b4.c6 to I.A.a2688.b4.c6).

Table 95: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-6 of table C (compounds I.A.a1 .b19.c6 to I.A.a2688.b19.c6).

Table 96: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-7 of table C (compounds I.Aa1.b1 .c7 to I.A.a2688.b1 .c7).

Table 97: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-7 of table C (compounds I.A.a1 .b4.c7 to I.A.a2688.b4.c7).

Table 98: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-7 of table C (compounds I.A.a1 .b19.c7 to I.A.a2688.b19.c7). Table 99: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-8 of table C (compounds I.A.a1 .b1 .c8 to I.A.a2688.b1 .c8).

Table 100: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-8 of table C (compounds I.A.a1 .b4.c8 to I.A.a2688.b4.c8).

Table 101 : Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-8 of table C (compounds I.A.a1 .b19.c8 to I.A.a2688.b19.c8).

Table 102: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-9 of table C (compounds I.A.a1 .b1 .c9 to I.A.a2688.b1 .c9).

Table 103: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-9 of table C (compounds I.A.a1 .b4.c9 to I.A.a2688.b4.c9).

Table 104: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-9 of table C (compounds I.A.a1 .b19.c9 to I.A.a2688.b19.c9).

Table 105: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-10 of table C (compounds I.A.a1 .b1 .c10 to I.A.a2688.b1.c10).

Table 106: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-10 of table C (compounds I.A.a1 .b4.c10 to I.A.a2688.b4.c10).

Table 107: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-10 of table C (compounds I.A.a1 .b19.c10 to I.A.a2688.b19.c10).

Table 108: Compounds I .A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 1 of table C (compounds I.A.a1 .b1 .c1 1 to I.A.a2688.b1.c1 1 ).

Table 109: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 1 of table C (compounds I.A.a1 .b4.c1 1 to I.A.a2688.b4.c1 1 ).

Table 1 10: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 1 of table C (compounds I.Aa1 .b19.c1 1 to I.A.a2688.b19.c1 1 ).

Table 1 1 1 : Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-12 of table C (compounds I.A.a1 .b1 .c12 to I.A.a2688.b1.c12).

Table 1 12: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-12 of table C (compounds I.A.a1 .b4.c12 to I.A.a2688.b4.c12).

Table 1 13: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-12 of table C (compounds I.A.a1 .b19.c12 to I.A.a2688.b19.c12).

Table 1 14: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-13 of table C (compounds I.A.a1 .b1 .c13 to I.A.a2688.b1.c13).

Table 1 15: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-13 of table C (compounds I.A.a1 .b4.c13 to I.A.a2688.b4.c13). Table 1 16: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-13 of table C (compounds I.A.a1 .b19.c13 to I.A.a2688.b19.c13).

Table 1 17: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-14 of table C (compounds I.A.a1.b1.c14 to I.A.a2688.b1.c14).

Table 1 18: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-14 of table C (compounds I.A.a1 .b4.c14 to I.A.a2688.b4.c14).

Table 1 19: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-14 of table C (compounds I.A.a1 .b19.c14 to I.A.a2688.b19.c14).

Table 120: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-15 of table C (compounds I.A.a1 .b1 .c15 to I.A.a2688.b1.c15).

Table 121 : Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-15 of table C (compounds I.A.a1 .b4.c15 to I.A.a2688.b4.c15).

Table 122: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-15 of table C (compounds I.A.a1 .b19.c15 to I.A.a2688.b19.c15).

Table 123: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-16 of table C (compounds I.A.a1 .b1 .c16 to I.A.a2688.b1.c16).

Table 124: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-16 of table C (compounds I.A.a1.b4.c16 to I.A.a2688.b4.c16).

Table 125: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-16 of table C (compounds I.A.a1 .b19.c16 to I.A.a2688.b19.c16).

Table 126: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-17 of table C (compounds I.A.a1 .b1 .c17 to I.A.a2688.b1.c17).

Table 127: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-17 of table C (compounds I.A.a1 .b4.c17 to I.A.a2688.b4.c17).

Table 128: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-17 of table C (compounds I.A.a1 .b19.c17 to I.A.a2688.b19.c17).

Table 129: Compounds I .A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-1 of table Z (compounds I.A.al .b1 .z1 to

I.A.a2688.b1.z1 ).

Table 130: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-1 of table Z (compounds I.A.al . b4.z1 to

I.A.a2688.b4.z1 ).

Table 131 : Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-1 of table Z (compounds I.A.al .b19.z1 to

I.A.a2688.b19.z1 ).

Table 132: Compounds I .A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-2 of table Z (compounds I.A.al .b1 .z2 to

I.A.a2688.b1.z2). Table 133: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-2 of table Z (compounds I.A.a1.b4.z2 to

I.A.a2688.b4.z2).

Table 134: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-2 of table Z (compounds I.A.al .b19.z2 to

I.A.a2688.b19.z2).

Table 135: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-3 of table Z (compounds I.A.al .b1 .z3 to

I.A.a2688.b1.z3).

Table 136: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-3 of table Z (compounds I.A.al . b4.z3 to

I.A.a2688.b4.z3).

Table 137: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-3 of table Z (compounds I.A.al .b19. z3 to

I.A.a2688.b19.z3).

Table 138: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-4 of table Z (compounds I.A.al .b1 .z4 to

I.A.a2688.b1.z4).

Table 139: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-4 of table Z (compounds I.A.al . b4.z4 to

I.A.a2688.b4.z4).

Table 140: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-4 of table Z (compounds I.A.al . b19. z4 to

I.A.a2688.b19.z4).

Table 141 : Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-5 of table Z (compounds I.A.al .b1 .z5 to

I.A.a2688.b1.z5).

Table 142: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-5 of table Z (compounds I.A.al . b4.z5 to

I.A.a2688.b4.z5).

Table 143: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-5 of table Z (compounds I.A.al .b19.z5 to

I.A.a2688.b19.z5).

Table 144: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-6 of table Z (compounds I.A.al .b1 .z6 to

I.A.a2688.b1.z6).

Table 145: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-6 of table Z (compounds I.A.al . b4.z6 to

I.A.a2688.b4.z6).

Table 146: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-6 of table Z (compounds I.A.al .b19. z6 to

I.A.a2688.b19.z6).

Table 147: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-7 of table Z (compounds I.A.al .b1 .z7 to

I.A.a2688.b1.z7).

Table 148: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-7 of table Z (compounds I.A.al . b4.z7 to

I.A.a2688.b4.z7).

Table 149: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-7 of table Z (compounds I.A.al .b19. z7 to

I.A.a2688.b19.z7). Table 150: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-8 of table Z (compounds I.A.al .b1 .z8 to

I.A.a2688.b1.z8).

Table 151 : Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-8 of table Z (compounds I.A.al . b4.z8 to

I.A.a2688.b4.z8).

Table 152: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-8 of table Z (compounds I.A.al .b19. z8 to

I.A.a2688.b19.z8).

Table 153: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-9 of table Z (compounds I.A.al .b1 .z9 to

I.A.a2688.b1.z9).

Table 154: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-9 of table Z (compounds I.A.al . b4.z9 to

I.A.a2688.b4.z9).

Table 155: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-9 of table Z (compounds I.A.al .b19. z9 to

I.A.a2688.b19.z9).

Table 156: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-10 of table Z (compounds I.A.al . b1.z10 to I.A.a2688.b1 .z10).

Table 157: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-10 of table Z (compounds I.A.al . b4.z10 to I.A.a2688.b4.z10).

Table 158: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-10 of table Z (compounds I.A.a1.b19.z10 to I.A.a2688.b19.z10).

Table 159: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-1 1 of table Z (compounds I.A.al .b1.z1 1 to I.A.a2688.b1 .z1 1 ).

Table 160: Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-1 1 of table Z (compounds I.A.al .b4.z1 1 to I.A.a2688.b4.z1 1 ).

Table 161 : Compounds I. A , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-1 1 of table Z (compounds I.A.al . b19. z1 1 to I.A.a2688.b19.z1 1 ).

Table 162: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B (compounds I. B.a1.b1 to I.B.a672.b1 ).

Table 163: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-2 in Table B (compounds I. B.a1.b2 to I.B.a672.b2).

Table 164: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-3 in Table B (compounds I. B.a1.b3 to I.B.a672.b3).

Table 165: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B (compounds I. B.a1.b4 to I.B.a672.b4).

Table 166: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-5 in Table B (compounds I. B.a1.b5 to I.B.a672.b5).

Table 167: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-6 in Table B (compounds I. B.a1.b6 to I.B.a672.b6).

Table 168: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-7 in Table B (compounds I. B.a1.b7 to I.B.a672.b7).

Table 169: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-8 in Table B (compounds I. B.a1.b8 to I.B.a672.b8).

Table 170: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-9 in Table B (compounds I. B.a1.b9 to l.B.a672.b9).

Table 171 : Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-10 in Table B (compounds I. B.a1 .b10 to I.B.a672.b10).

Table 172: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 1 in Table B (compounds I. B.a1.b1 1 to I.B.a672.b1 1 ).

Table 173: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-12 in Table B (compounds I. B.a1.b12 to I.B.a672.b12).

Table 174: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-13 in Table B (compounds I. B.a1.b13 to I.B.a672.b13).

Table 175: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-14 in Table B (compounds I. B.a1.b14 to I.B.a672.b14).

Table 176: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-15 in Table B (compounds I. B.a1.b15 to I.B.a672.b15).

Table 177: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-16 in Table B (compounds I. B.a1.b16 to I.B.a672.b16).

Table 178: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-17 in Table B (compounds I. B.a1.b17 to I.B.a672.b17). Table 179: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-18 in Table B (compounds I. B.a1.b18 to I.B.a672.b18).

Table 180: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B (compounds I. B.a1.b19 to I.B.a672.b19).

Table 181 : Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-20 in Table B (compounds I. B.a1.b20 to I.B.a672.b20).

Table 182: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-21 in Table B (compounds I. B.a1.b21 to I.B.a672.b21 ).

Table 183: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-22 in Table B (compounds I. B.a1.b22 to I.B.a672.b22).

Table 184: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-23 in Table B (compounds I. B.a1.b23 to I.B.a672.b23).

Table 185: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-24 in Table B (compounds I. B.a1.b24 to I.B.a672.b24).

Table 186: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-25 in Table B (compounds I. B.a1.b25 to I.B.a672.b25).

Table 187: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-26 in Table B (compounds I. B.a1.b26 to I.B.a672.b26).

Table 188: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-27 in Table B (compounds I. B.a1.b27 to I.B.a672.b27).

Table 189: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-28 in Table B (compounds I. B.a1.b28 to I.B.a672.b28).

Table 190: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-29 in Table B (compounds I. B.a1.b29 to I.B.a672.b29).

Table 191 : Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-30 in Table B (compounds I. B.a1 .b30 to l.B.a672.b30).

Table 192: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-31 in Table B (compounds I. B.a1.b31 to I.B.a672.b31 ).

Table 193: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-32 in Table B (compounds I. B.a1.b32 to I.B.a672.b32).

Table 194: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-33 in Table B (compounds I. B.a1.b33 to I.B.a672.b33).

Table 195: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-34 in Table B (compounds I. B.a1.b34 to I.B.a672.b34).

Table 196: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-35 in Table B (compounds I. B.a1.b35 to I.B.a672.b35).

Table 197: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-36 in Table B (compounds I. B.a1.b36 to I.B.a672.b36).

Table 198: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-37 in Table B (compounds I. B.a1.b37 to I.B.a672.b37).

Table 199: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-38 in Table B (compounds I. B.a1.b38 to I.B.a672.b38). Table 200: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-39 in Table B (compounds I. B.a1.b39 to I.B.a672.b39).

Table 201 : Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-40 in Table B (compounds I. B.a1.b40 to I.B.a672.b40).

Table 202: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-41 in Table B (compounds I. B.a1.b41 to I.B.a672.b41 ).

Table 203: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-42 in Table B (compounds I. B.a1.b42 to I.B.a672.b42).

Table 204: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-43 in Table B (compounds I. B.a1.b43 to I.B.a672.b43).

Table 205: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-44 in Table B (compounds I. B.a1.b44 to I.B.a672.b44).

Table 206: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-45 in Table B (compounds I. B.a1.b45 to I.B.a672.b45).

Table 207: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-46 in Table B (compounds I. B.a1.b46 to I.B.a672.b46).

Table 208: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-47 in Table B (compounds I. B.a1.b47 to I.B.a672.b47).

Table 209: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-48 in Table B (compounds I. B.a1.b48 to I.B.a672.b48).

Table 210: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-49 in Table B (compounds I. B.a1 .b49 to I.B.a672.b49).

Table 21 1 : Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-50 in Table B (compounds I. B.a1 .b50 to I.B.a672.b50).

Table 212: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-51 in Table B (compounds I. B.a1.b51 to I.B.a672.b51 ).

Table 213: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-52 in Table B (compounds I. B.a1.b52 to I.B.a672.b52).

Table 214: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-53 in Table B (compounds I. B.a1.b53 to I.B.a672.b53).

Table 215: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-54 in Table B (compounds I. B.a1.b54 to I.B.a672.b54).

Table 216: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-55 in Table B (compounds I. B.a1.b55 to I.B.a672.b55).

Table 217: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-56 in Table B (compounds I. B.a1.b56 to I.B.a672.b56).

Table 218: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-57 in Table B (compounds I. B.a1.b57 to I.B.a672.b57).

Table 219: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-58 in Table B (compounds I. B.a1.b58 to I.B.a672.b58).

Table 220: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-59 in Table B (compounds I. B.a1.b59 to I.B.a672.b59). Table 221 : Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-60 in Table B (compounds I. B.a1.b60 to I.B.a672.b60).

Table 222: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-61 in Table B (compounds I. B.a1.b61 to I.B.a672.b61 ).

Table 223: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-62 in Table B (compounds I. B.a1.b62 to I.B.a672.b62).

Table 224: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-63 in Table B (compounds I. B.a1.b63 to I.B.a672.b63).

Table 225: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-64 in Table B (compounds I. B.a1.b64 to I.B.a672.b64).

Table 226: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-65 in Table B (compounds I. B.a1.b65 to I.B.a672.b65).

Table 227: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-66 in Table B (compounds I. B.a1.b66 to I.B.a672.b66).

Table 228: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-67 in Table B (compounds I. B.a1.b67 to I.B.a672.b67).

Table 229: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-68 in Table B (compounds I. B.a1.b68 to I.B.a672.b68).

Table 230: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-69 in Table B (compounds I. B.a1 .b69 to I.B.a672.b69).

Table 231 : Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-70 in Table B (compounds I. B.a1.b70 to I.B.a672.b70).

Table 232: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-71 in Table B (compounds I. B.a1.b71 to I.B.a672.b71 ).

Table 233: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-72 in Table B (compounds I. B.a1.b72 to l.B.a672.b72).

Table 234: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-73 in Table B (compounds I. B.a1.b73 to I.B.a672.b73).

Table 235: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-74 in Table B (compounds I. B.a1.b74 to I.B.a672.b74).

Table 236: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-75 in Table B (compounds I. B.a1.b75 to I.B.a672.b75).

Table 237: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-76 in Table B (compounds I. B.a1.b76 to I.B.a672.b76).

Table 238: Compounds I.B , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-77 in Table B (compounds I. B.a1.b77 to I.B.a672.b77).

Table 239: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 of table C (compounds I.B.a1 .b1 .c1 to I.B.a2688.b1 .d ).

Table 240: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 of table C (compounds I.B.a1 .b4.c1 to I.B.a2688.b4.c1 ).

Table 241 : Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 of table C (compounds I.B.a1 .b19.c1 to I.B.a2688.b19.c1 ).

Table 242: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-2 of table C (compounds I.B.a1 .b1 .c2 to I.B.a2688.b1 .c2).

Table 243: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-2 of table C (compounds I.B.a1 .b4.c2 to I.B.a2688.b4.c2).

Table 244: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-2 of table C (compounds I.B.a1 .b19.c2 to I.B.a2688.b19.c2).

Table 245: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-3 of table C (compounds I.B.a1 .b1 .c3 to I.B.a2688.b1 .c3).

Table 246: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-3 of table C (compounds I.B.a1 .b4.c3 to I.B.a2688.b4.c3).

Table 247: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-3 of table C (compounds I.B.a1 .b19.c3 to I.B.a2688.b19.c3).

Table 248: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-4 of table C (compounds I.B.a1 .b1 .c4 to I.B.a2688.b1 .c4).

Table 249: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-4 of table C (compounds I.B.al .b4.c4 to I.B.a2688.b4.c4). Table 250: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-4 of table C (compounds I.B.a1 .b19.c4 to I.B.a2688.b19.c4).

Table 251 : Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-5 of table C (compounds I.B.a1 .b1 .c5 to I.B.a2688.b1 .c5).

Table 252: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-5 of table C (compounds I.B.a1 .b4.c5 to I.B.a2688.b4.c5).

Table 253: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-5 of table C (compounds I.B.a1 .b19.c5 to I.B.a2688.b19.c5).

Table 254: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-6 of table C (compounds I.B.al .b1 .c6 to I.B.a2688.b1 .c6).

Table 255: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-6 of table C (compounds I.B.al .b4.c6 to I.B.a2688.b4.c6).

Table 256: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-6 of table C (compounds I.B.a1 .b19.c6 to I.B.a2688.b19.c6).

Table 257: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-7 of table C (compounds I.B.al .b1 .c7 to I.B.a2688.b1 .c7).

Table 258: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-7 of table C (compounds I.B.a1 .b4.c7 to I.B.a2688.b4.c7).

Table 259: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-7 of table C (compounds I.B.a1 .b19.c7 to I.B.a2688.b19.c7).

Table 260: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-8 of table C (compounds I.B.al .b1 .c8 to I.B.a2688.b1 .c8).

Table 261 : Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-8 of table C (compounds I.B.a1 .b4.c8 to I.B.a2688.b4.c8).

Table 262: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-8 of table C (compounds I.B.a1 .b19.c8 to I.B.a2688.b19.c8).

Table 263: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-9 of table C (compounds I.B.al .b1 .c9 to I.B.a2688.b1.c9).

Table 264: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-9 of table C (compounds I.B.a1 .b4.c9 to I.B.a2688.b4.c9).

Table 265: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-9 of table C (compounds I.B.a1 .b19.c9 to I.B.a2688.b19.c9).

Table 266: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-10 of table C (compounds I.B.al .b1 .c10 to I.B.a2688.b1.c10). Table 267: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-10 of table C (compounds I.B.a1 .b4.c10 to I.B.a2688.b4.c10).

Table 268: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-10 of table C (compounds I.B.a1 .b19.c10 to I.B.a2688.b19.c10).

Table 269: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 1 of table C (compounds I.B.a1 .b1 .c1 1 to I.B.a2688.b1.c1 1 ).

Table 270: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 1 of table C (compounds I.B.a1 .b4.c1 1 to I.B.a2688.b4.c1 1 ).

Table 271 : Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 1 of table C (compounds I.B.a1 .b19.c1 1 to I.B.a2688.b19.c1 1 ).

Table 272: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-12 of table C (compounds I.B.a1 .b1 .c12 to I.B.a2688.b1.c12).

Table 273: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-12 of table C (compounds I.B.al .b4.c12 to I.B.a2688.b4.c12).

Table 274: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-12 of table C (compounds I.B.a1 .b19.c12 to I.B.a2688.b19.c12).

Table 275: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-13 of table C (compounds I.B.al .b1 .c13 to I.B.a2688.b1.c13).

Table 276: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-13 of table C (compounds I.B.al .b4.c13 to I.B.a2688.b4.c13).

Table 277: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-13 of table C (compounds I.B.al .b19.c13 to I.B.a2688.b19.c13).

Table 278: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-14 of table C (compounds I.B.al .b1 .c14 to I.B.a2688.b1.c14).

Table 279: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-14 of table C (compounds I.B.al .b4.c14 to I.B.a2688.b4.c14).

Table 280: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-14 of table C (compounds I.B.al .b19.c14 to I.B.a2688.b19.c14).

Table 281 : Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-15 of table C (compounds I.B.al .b1 .c15 to I.B.a2688.b1.c15).

Table 282: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-15 of table C (compounds I.B.a1 .b4.c15 to I.B.a2688.b4.c15).

Table 283: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-15 of table C (compounds I.B.al .b19.c15 to I.B.a2688.b19.c15). Table 284: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-16 of table C (compounds I.B.a1.b1.c16 to I.B.a2688.b1.c16).

Table 285: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-16 of table C (compounds I.B.a1 .b4.c16 to I.B.a2688.b4.c16).

Table 286: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-16 of table C (compounds I.B.a1 .b19.c16 to I.B.a2688.b19.c16).

Table 287: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-17 of table C (compounds I.B.a1 .b1 .c17 to I.B.a2688.b1.c17).

Table 288: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-17 of table C (compounds I.B.a1 .b4.c17 to I.B.a2688.b4.c17).

Table 289: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-17 of table C (compounds I.B.a1 .b19.c17 to I.B.a2688.b19.c17).

Table 290: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-1 of table Z (compounds I.B.al .b1 .z1 to

I.B.a2688.b1.z1 ).

Table 291 : Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-1 of table Z (compounds I.B.al .b4.z1 to

I.B.a2688.b4.z1 ).

Table 292: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-1 of table Z (compounds I.B.al .b19.z1 to

I.B.a2688.b19.z1 ).

Table 293: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-2 of table Z (compounds I.B.al .b1 .z2 to

I.B.a2688.b1.z2).

Table 294: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-2 of table Z (compounds I.B.a1.b4.z2 to

I.B.a2688.b4.z2).

Table 295: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-2 of table Z (compounds I.B.al .b19.z2 to

I.B.a2688.b19.z2).

Table 296: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-3 of table Z (compounds I.B.al .b1 .z3 to

I.B.a2688.b1.z3).

Table 297: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-3 of table Z (compounds I.B.al .b4.z3 to

I.B.a2688.b4.z3).

Table 298: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-3 of table Z (compounds I.B.al .b19.z3 to

I.B.a2688.b19.z3).

Table 299: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-4 of table Z (compounds I.B.al .b1 .z4 to

I.B.a2688.b1.z4).

Table 300: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-4 of table Z (compounds I.B.al .b4.z4 to

I.B.a2688.b4.z4). Table 301 : Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-4 of table Z (compounds I.B.al .b19.z4 to

I.B.a2688.b19.z4).

Table 302: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-5 of table Z (compounds I.B.al .b1 .z5 to

I.B.a2688.b1.z5).

Table 303: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-5 of table Z (compounds I.B.a1.b4.z5 to

I.B.a2688.b4.z5).

Table 304: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-5 of table Z (compounds I.B.al .b19.z5 to

I.B.a2688.b19.z5).

Table 305: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-6 of table Z (compounds I.B.al .b1 .z6 to

I.B.a2688.b1.z6).

Table 306: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-6 of table Z (compounds I.B.a1.b4.z6 to

I.B.a2688.b4.z6).

Table 307: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-6 of table Z (compounds I.B.al .b19.z6 to

I.B.a2688.b19.z6).

Table 308: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-7 of table Z (compounds I.B.al .b1 .z7 to

I.B.a2688.b1 .z7).

Table 309: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-7 of table Z (compounds I.B.a1.b4.z7 to

I.B.a2688.b4.z7).

Table 310: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-7 of table Z (compounds I.B.al .b19.z7 to

I.B.a2688.b19.z7).

Table 31 1 : Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-8 of table Z (compounds I.B.al .b1.z8 to

I.B.a2688.b1.z8).

Table 312: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-8 of table Z (compounds I.B.a1.b4.z8 to

I.B.a2688.b4.z8).

Table 313: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-8 of table Z (compounds I.B.al .b19.z8 to

I.B.a2688.b19.z8).

Table 314: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-9 of table Z (compounds I.B.al .b1 .z9 to

I.B.a2688.b1.z9).

Table 315: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-9 of table Z (compounds I.B.a1.b4.z9 to

I.B.a2688.b4.z9).

Table 316: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-9 of table Z (compounds I.B.al .b19.z9 to

I.B.a2688.b19.z9).

Table 317: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-10 of table Z (compounds I.B.al .b1.z10 to I.B.a2688.b1 .z10). Table 318: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-10 of table Z (compounds I.B.al .b4.z10 to I.B.a2688.b4.z10).

Table 319: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-10 of table Z (compounds I.B.a1.b19.z10 to I.B.a2688.b19.z10).

Table 320: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-1 1 of table Z (compounds I.B.al .b1.z1 1 to I.B.a2688.b1 .z1 1 ).

Table 321 : Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-1 1 of table Z (compounds I.B.al .b4.z1 1 to I.B.a2688.b4.z1 1 ).

Table 322: Compounds I.B , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-1 1 of table Z (compounds I.B.a1.b19.z1 1 to I.B.a2688.b19.z1 1 ).

Table 323: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B (compounds I. C.a1 .b1 to I.C.a672.b1 ).

Table 324: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-2 in Table B (compounds I. C.a1 .b2 to I.C.a672.b2).

Table 325: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-3 in Table B (compounds I. C.a1 .b3 to I.C.a672.b3).

Table 326: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B (compounds I. C.a1 .b4 to I.C.a672.b4).

Table 327: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-5 in Table B (compounds I. C.a1 .b5 to I.C.a672.b5).

Table 328: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-6 in Table B (compounds I. C.a1 .b6 to I.C.a672.b6).

Table 329: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-7 in Table B (compounds I. C.a1 .b7 to l.C.a672.b7).

Table 330: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-8 in Table B (compounds I. C.a1 .b8 to I.C.a672.b8).

Table 331 : Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-9 in Table B (compounds I. C.a1 .b9 to I.C.a672.b9).

Table 332: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-10 in Table B (compounds I. C.a1 .b10 to I.C.a672.b10).

Table 333: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 1 in Table B (compounds I. C.a1 .b1 1 to I.C.a672.b1 1 ).

Table 334: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-12 in Table B (compounds I. C.a1 .b12 to I.C.a672.b12).

Table 335: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-13 in Table B (compounds I. C.a1 .b13 to I.C.a672.b13).

Table 336: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-14 in Table B (compounds I. C.a1 .b14 to I.C.a672.b14).

Table 337: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-15 in Table B (compounds I. C.a1 .b15 to I.C.a672.b15). Table 338: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-16 in Table B (compounds I. C.a1 .b16 to I.C.a672.b16).

Table 339: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-17 in Table B (compounds I. C.a1 .b17 to I.C.a672.b17).

Table 340: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-18 in Table B (compounds I. C.a1 .b18 to I.C.a672.b18).

Table 341 : Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B (compounds I. C.a1 .b19 to I.C.a672.b19).

Table 342: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-20 in Table B (compounds I. C.a1 .b20 to I.C.a672.b20).

Table 343: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-21 in Table B (compounds I. C.a1 .b21 to I.C.a672.b21 ).

Table 344: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-22 in Table B (compounds I. C.a1.b22 to I.C.a672.b22).

Table 345: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-23 in Table B (compounds I. C.a1 .b23 to I.C.a672.b23).

Table 346: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-24 in Table B (compounds I. C.a1 .b24 to I.C.a672.b24).

Table 347: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-25 in Table B (compounds I. C.a1 .b25 to I.C.a672.b25).

Table 348: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-26 in Table B (compounds I. C.a1 .b26 to I.C.a672.b26).

Table 349: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-27 in Table B (compounds I. C.a1 .b27 to I.C.a672.b27).

Table 350: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-28 in Table B (compounds I. C.a1 .b28 to l.C.a672.b28).

Table 351 : Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-29 in Table B (compounds I. C.a1 .b29 to I.C.a672.b29).

Table 352: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-30 in Table B (compounds I. C.a1 .b30 to I.C.a672.b30).

Table 353: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-31 in Table B (compounds I. C.a1 .b31 to I.C.a672.b31 ).

Table 354: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-32 in Table B (compounds I. C.a1 .b32 to I.C.a672.b32).

Table 355: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-33 in Table B (compounds I. C.a1 .b33 to I.C.a672.b33).

Table 356: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-34 in Table B (compounds I. C.a1 .b34 to I.C.a672.b34).

Table 357: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-35 in Table B (compounds I. C.a1 .b35 to I.C.a672.b35).

Table 358: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-36 in Table B (compounds I. C.a1 .b36 to I.C.a672.b36). Table 359: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-37 in Table B (compounds I. C.a1 .b37 to I.C.a672.b37).

Table 360: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-38 in Table B (compounds I. C.a1 .b38 to I.C.a672.b38).

Table 361 : Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-39 in Table B (compounds I. C.a1 .b39 to I.C.a672.b39).

Table 362: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-40 in Table B (compounds I. C.a1 .b40 to I.C.a672.b40).

Table 363: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-41 in Table B (compounds I. C.a1.b41 to I.C.a672.b41 ).

Table 364: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-42 in Table B (compounds I. C.a1.b42 to I.C.a672.b42).

Table 365: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-43 in Table B (compounds I. C.a1 .b43 to I.C.a672.b43).

Table 366: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-44 in Table B (compounds I. C.a1 .b44 to I.C.a672.b44).

Table 367: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-45 in Table B (compounds I. C.a1 .b45 to I.C.a672.b45).

Table 368: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-46 in Table B (compounds I. C.a1 .b46 to I.C.a672.b46).

Table 369: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-47 in Table B (compounds I. C.a1 .b47 to I.C.a672.b47).

Table 370: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-48 in Table B (compounds I. C.a1 .b48 to I.C.a672.b48).

Table 371 : Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-49 in Table B (compounds I. C.a1 .b49 to l.C.a672.b49).

Table 372: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-50 in Table B (compounds I. C.a1 .b50 to I.C.a672.b50).

Table 373: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-51 in Table B (compounds I. C.a1 .b51 to I.C.a672.b51 ).

Table 374: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-52 in Table B (compounds I. C.a1 .b52 to I.C.a672.b52).

Table 375: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-53 in Table B (compounds I. C.a1 .b53 to I.C.a672.b53).

Table 376: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-54 in Table B (compounds I. C.a1 .b54 to I.C.a672.b54).

Table 377: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-55 in Table B (compounds I. C.a1 .b55 to I.C.a672.b55).

Table 378: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-56 in Table B (compounds I. C.a1 .b56 to I.C.a672.b56).

Table 379: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-57 in Table B (compounds I. C.a1 .b57 to I.C.a672.b57). Table 380: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-58 in Table B (compounds I. C.a1 .b58 to I.C.a672.b58).

Table 381 : Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-59 in Table B (compounds I. C.a1 .b59 to I.C.a672.b59).

Table 382: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-60 in Table B (compounds I. C.a1 .b60 to I.C.a672.b60).

Table 383: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-61 in Table B (compounds I. C.a1.b61 to I.C.a672.b61 ).

Table 384: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-62 in Table B (compounds I. C.a1 .b62 to I.C.a672.b62).

Table 385: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-63 in Table B (compounds I. C.a1 .b63 to I.C.a672.b63).

Table 386: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-64 in Table B (compounds I. C.a1 .b64 to I.C.a672.b64).

Table 387: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-65 in Table B (compounds I. C.a1 .b65 to I.C.a672.b65).

Table 388: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-66 in Table B (compounds I. C.a1 .b66 to I.C.a672.b66).

Table 389: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-67 in Table B (compounds I. C.a1 .b67 to I.C.a672.b67).

Table 390: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-68 in Table B (compounds I. C.a1 .b68 to I.C.a672.b68).

Table 391 : Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-69 in Table B (compounds I. C.a1 .b69 to I.C.a672.b69).

Table 392: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-70 in Table B (compounds I. C.a1 .b70 to l.C.a672.b70).

Table 393: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-71 in Table B (compounds I. C.a1 .b71 to I.C.a672.b71 ).

Table 394: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-72 in Table B (compounds I. C.a1 .b72 to I.C.a672.b72).

Table 395: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-73 in Table B (compounds I. C.a1 .b73 to I.C.a672.b73).

Table 396: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-74 in Table B (compounds I. C.a1 .b74 to I.C.a672.b74).

Table 397: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-75 in Table B (compounds I. C.a1 .b75 to I.C.a672.b75).

Table 398: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-76 in Table B (compounds I. C.a1 .b76 to I.C.a672.b76).

Table 399: Compounds I.C , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-77 in Table B (compounds I. C.a1 .b77 to I.C.a672.b77).

Table 400: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 of table C (compounds I.C.a1.b1.c1 to I.C.a2688.b1 .c1 ). Table 401 : Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 of table C (compounds I.C.a1.b4.c1 to I.C.a2688.b4.c1 ).

Table 402: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 of table C (compounds I.C.a1.b19.c1 to I.C.a2688.b19.c1 ).

Table 403: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-2 of table C (compounds I.C.a1.b1.c2 to I.C.a2688.b1 .c2).

Table 404: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-2 of table C (compounds I.C.al .b4.c2 to I.C.a2688.b4.c2).

Table 405: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-2 of table C (compounds I.C.al . b19.c2 to I.C.a2688.b19.c2).

Table 406: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-3 of table C (compounds I.C.al .b1.c3 to I.C.a2688.b1 .c3).

Table 407: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-3 of table C (compounds I.C.al .b4.c3 to I.C.a2688.b4.c3).

Table 408: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-3 of table C (compounds I.C.al . b19.c3 to I.C.a2688.b19.c3).

Table 409: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-4 of table C (compounds I.C.al .b1 .c4 to I.C.a2688.b1 .c4).

Table 410: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-4 of table C (compounds I.C.a1.b4.c4 to I.C.a2688.b4.c4).

Table 41 1 : Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-4 of table C (compounds I.C.al . b19.c4 to I.C.a2688.b19.c4).

Table 412: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-5 of table C (compounds I.C.al .b1.c5 to I.C.a2688.b1 .c5).

Table 413: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-5 of table C (compounds I.C.al . b4.c5 to I.C.a2688.b4.c5).

Table 414: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-5 of table C (compounds I.C.al . b19.c5 to I.C.a2688.b19.c5).

Table 415: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-6 of table C (compounds I.C.al .b1.c6 to I.C.a2688.b1 .c6).

Table 416: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-6 of table C (compounds I.C.al . b4.c6 to I.C.a2688.b4.c6).

Table 417: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-6 of table C (compounds I.C.al . b19.c6 to I.C.a2688.b19.c6). Table 418: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-7 of table C (compounds I.C.al .b1.c7 to I.C.a2688.b1 .c7).

Table 419: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-7 of table C (compounds I.C.al . b4.c7 to I.C.a2688.b4.c7).

Table 420: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-7 of table C (compounds I.C.al . b19.c7 to I.C.a2688.b19.c7).

Table 421 : Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-8 of table C (compounds I.C.al .b1.c8 to I.C.a2688.b1 .c8).

Table 422: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-8 of table C (compounds I.C.al .b4.c8 to I.C.a2688.b4.c8).

Table 423: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-8 of table C (compounds I.C.al . b19.c8 to I.C.a2688.b19.c8).

Table 424: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-9 of table C (compounds I.C.al .b1.c9 to I.C.a2688.b1 .c9).

Table 425: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-9 of table C (compounds I.C.al .b4.c9 to I.C.a2688.b4.c9).

Table 426: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-9 of table C (compounds I.C.a1.b19.c9 to I.C.a2688.b19.c9).

Table 427: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-10 of table C (compounds I.C.a1.b1.c10 to I.C.a2688.b1.c10).

Table 428: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-10 of table C (compounds I.C.a1 .b4.c10 to I.C.a2688.b4.c10).

Table 429: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-10 of table C (compounds I.C.a1.b19.c10 to I.C.a2688.b19.c10).

Table 430: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 1 of table C (compounds I.C.a1.b1.c1 1 to I.C.a2688.b1.c1 1 ).

Table 431 : Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 1 of table C (compounds I.C.a1.b4.c1 1 to I.C.a2688.b4.c1 1 ).

Table 432: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 1 of table C (compounds I.C.a1.b19.c1 1 to I.C.a2688.b19.c1 1 ).

Table 433: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-12 of table C (compounds I.C.a1.b1.c12 to I.C.a2688.b1.c12).

Table 434: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-12 of table C (compounds I.C.a1.b4.c12 to I.C.a2688.b4.c12). Table 435: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-12 of table C (compounds I.C.a1.b19.c12 to I.C.a2688.b19.c12).

Table 436: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-13 of table C (compounds I.C.a1.b1.c13 to I.C.a2688.b1.c13).

Table 437: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-13 of table C (compounds I.C.a1.b4.c13 to I.C.a2688.b4.c13).

Table 438: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-13 of table C (compounds I.C.a1.b19.c13 to I.C.a2688.b19.c13).

Table 439: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-14 of table C (compounds I.C.a1.b1.c14 to I.C.a2688.b1.c14).

Table 440: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-14 of table C (compounds I.C.al .b4.c14 to I.C.a2688.b4.c14).

Table 441 : Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-14 of table C (compounds I.C.al . b19.c14 to I.C.a2688.b19.c14).

Table 442: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-15 of table C (compounds I.C.al . b1.c15 to I.C.a2688.b1.c15).

Table 443: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-15 of table C (compounds I.C.a1.b4.c15 to I.C.a2688.b4.c15).

Table 444: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-15 of table C (compounds I.C.a1.b19.c15 to I.C.a2688.b19.c15).

Table 445: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-16 of table C (compounds I.C.a1.b1.c16 to I.C.a2688.b1.c16).

Table 446: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-16 of table C (compounds I.C.a1.b4.c16 to I.C.a2688.b4.c16).

Table 447: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-16 of table C (compounds I.C.a1.b19.c16 to I.C.a2688.b19.c16).

Table 448: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-17 of table C (compounds I.C.a1.b1.c17 to I.C.a2688.b1.c17).

Table 449: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-17 of table C (compounds I.C.a1.b4.c17 to I.C.a2688.b4.c17).

Table 450: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-17 of table C (compounds I.C.a1.b19.c17 to I.C.a2688.b19.c17).

Table 451 : Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-1 of table Z (compounds I.C.al .b1 .z1 to

I.C.a2688.b1 .z1 ). Table 452: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-1 of table Z (compounds I.C.al .b4.z1 to

I.C.a2688.b4.z1 ).

Table 453: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-1 of table Z (compounds I.C.al .b19.z1 to

I.C.a2688.b19.z1 ).

Table 454: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-2 of table Z (compounds I.C.al .b1.z2 to

I.C.a2688.b1.z2).

Table 455: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-2 of table Z (compounds I.C.a1.b4.z2 to

I.C.a2688.b4.z2).

Table 456: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-2 of table Z (compounds I.C.al .b19.z2 to

I.C.a2688.b19.z2).

Table 457: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-3 of table Z (compounds I.C.al .b1.z3 to

I.C.a2688.b1.z3).

Table 458: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-3 of table Z (compounds I.C.a1.b4.z3 to

I.C.a2688.b4.z3).

Table 459: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-3 of table Z (compounds I.C.al .b19.z3 to

I.C.a2688.b19.z3).

Table 460: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-4 of table Z (compounds I.C.al .b1.z4 to

I.C.a2688.b1.z4).

Table 461 : Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-4 of table Z (compounds I.C.al . b4.z4 to

I.C.a2688.b4.z4).

Table 462: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-4 of table Z (compounds I.C.al .b19.z4 to

I.C.a2688.b19.z4).

Table 463: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-5 of table Z (compounds I.C.al .b1 .z5 to

I.C.a2688.b1.z5).

Table 464: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-5 of table Z (compounds I.C.a1.b4.z5 to

I.C.a2688.b4.z5).

Table 465: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-5 of table Z (compounds I.C.al .b19.z5 to

I.C.a2688.b19.z5).

Table 466: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-6 of table Z (compounds I.C.al .b1 .z6 to

I.C.a2688.b1.z6).

Table 467: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-6 of table Z (compounds I.C.a1.b4.z6 to

I.C.a2688.b4.z6).

Table 468: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-6 of table Z (compounds I.C.al .b19.z6 to

I.C.a2688.b19.z6). Table 469: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-7 of table Z (compounds I.C.al .b1 .z7 to

I.C.a2688.b1.z7).

Table 470: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-7 of table Z (compounds I.C.a1.b4.z7 to

I.C.a2688.b4.z7).

Table 471 : Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-7 of table Z (compounds I.C.al .b19.z7 to

I.C.a2688.b19.z7).

Table 472: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-8 of table Z (compounds I.C.al .b1 .z8 to

I.C.a2688.b1.z8).

Table 473: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-8 of table Z (compounds I.C.a1.b4.z8 to

I.C.a2688.b4.z8).

Table 474: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-8 of table Z (compounds I.C.al .b19.z8 to

I.C.a2688.b19.z8).

Table 475: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-9 of table Z (compounds I.C.al .b1 .z9 to

I.C.a2688.b1.z9).

Table 476: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-9 of table Z (compounds I.C.a1.b4.z9 to

I.C.a2688.b4.z9).

Table 477: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-9 of table Z (compounds I.C.al .b19.z9 to

I.C.a2688.b19.z9).

Table 478: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-10 of table Z (compounds I.C.al .b1.z10 to I.C.a2688.b1 .z10).

Table 479: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-10 of table Z (compounds I.C.al .b4.z10 to I.C.a2688.b4.z10).

Table 480: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-10 of table Z (compounds I.C.a1.b19.z10 to

I.C.a2688.b19.z10).

Table 481 : Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-1 1 of table Z (compounds I.C.al .b1.z1 1 to

I.C.a2688.b1 .z1 1 ).

Table 482: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-1 1 of table Z (compounds I.C.al .b4.z1 1 to I.C.a2688.b4.z1 1 ).

Table 483: Compounds I.C , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-1 1 of table Z (compounds I.C.a1.b19.z1 1 to I.C.a2688.b19.z1 1 ).

Table 484: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B (compounds I. D.a1 .b1 to I.D.a672.b1 ).

Table 485: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-2 in Table B (compounds I. D.a1 .b2 to I.D.a672.b2).

Table 486: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-3 in Table B (compounds I. D.a1 .b3 to I.D.a672.b3).

Table 487: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B (compounds I. D.a1 .b4 to I.D.a672.b4).

Table 488: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-5 in Table B (compounds I. D.a1 .b5 to l.D.a672.b5).

Table 489: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-6 in Table B (compounds I. D.a1 .b6 to I.D.a672.b6).

Table 490: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-7 in Table B (compounds I. D.a1 .b7 to I.D.a672.b7).

Table 491 : Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-8 in Table B (compounds I. D.a1 .b8 to I.D.a672.b8).

Table 492: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-9 in Table B (compounds I. D.a1 .b9 to I.D.a672.b9).

Table 493: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-10 in Table B (compounds I. D.a1 .b10 to I.D.a672.b10).

Table 494: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 1 in Table B (compounds I. D.a1 .b1 1 to I.D.a672.b1 1 ).

Table 495: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-12 in Table B (compounds I. D.a1 .b12 to I.D.a672.b12).

Table 496: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-13 in Table B (compounds I. D.a1 .b13 to I.D.a672.b13). Table 497: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-14 in Table B (compounds I. D.a1.b14 to I.D.a672.b14).

Table 498: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-15 in Table B (compounds I. D.a1 .b15 to I.D.a672.b15).

Table 499: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-16 in Table B (compounds I. D.a1 .b16 to I.D.a672.b16).

Table 500: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-17 in Table B (compounds I. D.a1 .b17 to I.D.a672.b17).

Table 501 : Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-18 in Table B (compounds I. D.a1 .b18 to I.D.a672.b18).

Table 502: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B (compounds I. D.a1 .b19 to I.D.a672.b19).

Table 503: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-20 in Table B (compounds I. D.a1 .b20 to I.D.a672.b20).

Table 504: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-21 in Table B (compounds I. D.a1 .b21 to I.D.a672.b21 ).

Table 505: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-22 in Table B (compounds I. D.a1 .b22 to I.D.a672.b22).

Table 506: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-23 in Table B (compounds I. D.a1 .b23 to I.D.a672.b23).

Table 507: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-24 in Table B (compounds I. D.a1 .b24 to I.D.a672.b24).

Table 508: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-25 in Table B (compounds I. D.a1 .b25 to I.D.a672.b25).

Table 509: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-26 in Table B (compounds I. D.a1 .b26 to l.D.a672.b26).

Table 510: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-27 in Table B (compounds I. D.a1 .b27 to I.D.a672.b27).

Table 51 1 : Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-28 in Table B (compounds I. D.a1 .b28 to I.D.a672.b28).

Table 512: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-29 in Table B (compounds I. D.a1 .b29 to I.D.a672.b29).

Table 513: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-30 in Table B (compounds I. D.a1 .b30 to I.D.a672.b30).

Table 514: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-31 in Table B (compounds I. D.a1 .b31 to I.D.a672.b31 ).

Table 515: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-32 in Table B (compounds I. D.a1 .b32 to I.D.a672.b32).

Table 516: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-33 in Table B (compounds I. D.a1.b33 to I.D.a672.b33).

Table 517: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-34 in Table B (compounds I. D.a1.b34 to I.D.a672.b34). Table 518: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-35 in Table B (compounds I. D.a1 .b35 to I.D.a672.b35).

Table 519: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-36 in Table B (compounds I. D.a1 .b36 to I.D.a672.b36).

Table 520: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-37 in Table B (compounds I. D.a1 .b37 to I.D.a672.b37).

Table 521 : Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-38 in Table B (compounds I. D.a1 .b38 to I.D.a672.b38).

Table 522: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-39 in Table B (compounds I. D.a1 .b39 to I.D.a672.b39).

Table 523: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-40 in Table B (compounds I. D.a1 .b40 to I.D.a672.b40).

Table 524: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-41 in Table B (compounds I. D.a1 .b41 to I.D.a672.b41 ).

Table 525: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-42 in Table B (compounds I. D.a1 .b42 to I.D.a672.b42).

Table 526: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-43 in Table B (compounds I. D.a1 .b43 to I.D.a672.b43).

Table 527: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-44 in Table B (compounds I. D.a1 .b44 to I.D.a672.b44).

Table 528: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-45 in Table B (compounds I. D.a1 .b45 to I.D.a672.b45).

Table 529: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-46 in Table B (compounds I. D.a1 .b46 to I.D.a672.b46).

Table 530: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-47 in Table B (compounds I. D.a1 .b47 to l.D.a672.b47).

Table 531 : Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-48 in Table B (compounds I. D.a1 .b48 to I.D.a672.b48).

Table 532: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-49 in Table B (compounds I. D.a1 .b49 to I.D.a672.b49).

Table 533: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-50 in Table B (compounds I. D.a1 .b50 to I.D.a672.b50).

Table 534: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-51 in Table B (compounds I. D.a1 .b51 to I.D.a672.b51 ).

Table 535: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-52 in Table B (compounds I. D.a1 .b52 to I.D.a672.b52).

Table 536: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-53 in Table B (compounds I. D.a1.b53 to I.D.a672.b53).

Table 537: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-54 in Table B (compounds I. D.a1 .b54 to I.D.a672.b54).

Table 538: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-55 in Table B (compounds I. D.a1 .b55 to I.D.a672.b55). Table 539: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-56 in Table B (compounds I. D.a1 .b56 to I.D.a672.b56).

Table 540: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-57 in Table B (compounds I. D.a1 .b57 to I.D.a672.b57).

Table 541 : Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-58 in Table B (compounds I. D.a1 .b58 to I.D.a672.b58).

Table 542: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-59 in Table B (compounds I. D.a1 .b59 to I.D.a672.b59).

Table 543: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-60 in Table B (compounds I. D.a1 .b60 to I.D.a672.b60).

Table 544: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-61 in Table B (compounds I. D.a1 .b61 to I.D.a672.b61 ).

Table 545: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-62 in Table B (compounds I. D.a1 .b62 to I.D.a672.b62).

Table 546: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-63 in Table B (compounds I. D.a1 .b63 to I.D.a672.b63).

Table 547: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-64 in Table B (compounds I. D.a1 .b64 to I.D.a672.b64).

Table 548: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-65 in Table B (compounds I. D.a1 .b65 to I.D.a672.b65).

Table 549: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-66 in Table B (compounds I. D.a1 .b66 to I.D.a672.b66).

Table 550: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-67 in Table B (compounds I. D.a1 .b67 to I.D.a672.b67).

Table 551 : Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-68 in Table B (compounds I. D.a1 .b68 to l.D.a672.b68).

Table 552: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-69 in Table B (compounds I. D.a1 .b69 to I.D.a672.b69).

Table 553: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-70 in Table B (compounds I. D.a1 .b70 to I.D.a672.b70).

Table 554: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-71 in Table B (compounds I. D.a1 .b71 to I.D.a672.b71 ).

Table 555: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-72 in Table B (compounds I. D.a1.b72 to I.D.a672.b72).

Table 556: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-73 in Table B (compounds I. D.a1.b73 to I.D.a672.b73).

Table 557: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-74 in Table B (compounds I. D.a1 .b74 to I.D.a672.b74).

Table 558: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-75 in Table B (compounds I. D.a1 .b75 to I.D.a672.b75).

Table 559: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-76 in Table B (compounds I. D.a1 .b76 to I.D.a672.b76). Table 560: Compounds I.D , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-77 in Table B (compounds I. D.a1 .b77 to I.D.a672.b77).

Table 561 : Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 of table C (compounds I.D.a1.b1.c1 to I.D.a2688.b1 .c1 ).

Table 562: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 of table C (compounds I.D.a1 .b4.c1 to I.D.a2688.b4.c1 ).

Table 563: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 of table C (compounds I.D.a1.b19.c1 to I.D.a2688.b19.c1 ).

Table 564: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-2 of table C (compounds I.D.al .b1.c2 to I.D.a2688.b1 .c2).

Table 565: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-2 of table C (compounds I.D.a1.b4.c2 to I.D.a2688.b4.c2).

Table 566: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-2 of table C (compounds I.D.a1.b19.c2 to I.D.a2688.b19.c2).

Table 567: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-3 of table C (compounds I.D.al .b1.c3 to I.D.a2688.b1 .c3).

Table 568: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-3 of table C (compounds I.D.a1.b4.c3 to I.D.a2688.b4.c3).

Table 569: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-3 of table C (compounds I.D.a1.b19.c3 to I.D.a2688.b19.c3).

Table 570: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-4 of table C (compounds I.D.al .b1.c4 to I.D.a2688.b1 .c4).

Table 571 : Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-4 of table C (compounds I.D.a1.b4.c4 to I.D.a2688.b4.c4).

Table 572: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-4 of table C (compounds I.D.a1.b19.c4 to I.D.a2688.b19.c4).

Table 573: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-5 of table C (compounds I.D.al .b1.c5 to I.D.a2688.b1 .c5).

Table 574: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-5 of table C (compounds I.D.al .b4.c5 to I.D.a2688.b4.c5).

Table 575: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-5 of table C (compounds I.D.a1.b19.c5 to I.D.a2688.b19.c5).

Table 576: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-6 of table C (compounds I.D.al .b1.c6 to I.D.a2688.b1 .c6). Table 577: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-6 of table C (compounds I.D.al .b4.c6 to I.D.a2688.b4.c6).

Table 578: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-6 of table C (compounds I.D.a1.b19.c6 to I.D.a2688.b19.c6).

Table 579: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-7 of table C (compounds I.D.a1.b1.c7 to I.D.a2688.b1 .c7).

Table 580: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-7 of table C (compounds I.D.al .b4.c7 to I.D.a2688.b4.c7).

Table 581 : Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-7 of table C (compounds I.D.a1 .b19.c7 to I.D.a2688.b19.c7).

Table 582: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-8 of table C (compounds I.D.al .b1.c8 to I.D.a2688.b1 .c8).

Table 583: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-8 of table C (compounds I.D.al .b4.c8 to I.D.a2688.b4.c8).

Table 584: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-8 of table C (compounds I.D.a1.b19.c8 to I.D.a2688.b19.c8).

Table 585: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-9 of table C (compounds I.D.al .b1.c9 to I.D.a2688.b1 .c9).

Table 586: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-9 of table C (compounds I.D.a1.b4.c9 to I.D.a2688.b4.c9).

Table 587: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-9 of table C (compounds I.D.a1.b19.c9 to I.D.a2688.b19.c9).

Table 588: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-10 of table C (compounds I.D.al .b1 .c10 to I.D.a2688.b1.c10).

Table 589: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-10 of table C (compounds I.D.a1.b4.c10 to I.D.a2688.b4.c10).

Table 590: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-10 of table C (compounds I.D.a1.b19.c10 to I.D.a2688.b19.c10).

Table 591 : Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 1 of table C (compounds I.D.a1.b1.c1 1 to I.D.a2688.b1.c1 1 ).

Table 592: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 1 of table C (compounds I.D.a1.b4.c1 1 to I.D.a2688.b4.c1 1 ).

Table 593: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 1 of table C (compounds I.D.a1.b19.c1 1 to I.D.a2688.b19.c1 1 ). Table 594: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-12 of table C (compounds I.D.a1.b1.c12 to I.D.a2688.b1.c12).

Table 595: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-12 of table C (compounds I.D.a1 .b4.c12 to I.D.a2688.b4.c12).

Table 596: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-12 of table C (compounds I.D.a1.b19.c12 to I.D.a2688.b19.c12).

Table 597: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-13 of table C (compounds I.D.a1.b1.c13 to I.D.a2688.b1.c13).

Table 598: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-13 of table C (compounds I.D.a1.b4.c13 to I.D.a2688.b4.c13).

Table 599: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-13 of table C (compounds I.D.a1.b19.c13 to I.D.a2688.b19.c13).

Table 600: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-14 of table C (compounds I.D.a1.b1.c14 to I.D.a2688.b1.c14).

Table 601 : Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-14 of table C (compounds I.D.al .b4.c14 to I.D.a2688.b4.c14).

Table 602: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-14 of table C (compounds I.D.a1.b19.c14 to I.D.a2688.b19.c14).

Table 603: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-15 of table C (compounds I.D.a1.b1.c15 to I.D.a2688.b1.c15).

Table 604: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-15 of table C (compounds I.D.a1.b4.c15 to I.D.a2688.b4.c15).

Table 605: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-15 of table C (compounds I.D.a1.b19.c15 to I.D.a2688.b19.c15).

Table 606: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-16 of table C (compounds I.D.a1.b1.c16 to I.D.a2688.b1.c16).

Table 607: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-16 of table C (compounds I.D.a1.b4.c16 to I.D.a2688.b4.c16).

Table 608: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-16 of table C (compounds I.D.a1.b19.c16 to I.D.a2688.b19.c16).

Table 609: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-17 of table C (compounds I.D.a1.b1.c17 to I.D.a2688.b1.c17).

Table 610: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-17 of table C (compounds I.D.a1.b4.c17 to I.D.a2688.b4.c17). Table 61 1 : Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-17 of table C (compounds I.D.a1.b19.c17 to I.D.a2688.b19.c17).

Table 612: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-1 of table Z (compounds I.D.al .b1 .z1 to

I.D.a2688.b1.z1 ).

Table 613: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-1 of table Z (compounds I.D.al .b4.z1 to

I.D.a2688.b4.z1 ).

Table 614: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-1 of table Z (compounds I.D.a1.b19.z1 to

I.D.a2688.b19.z1 ).

Table 615: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-2 of table Z (compounds I.D.al .b1 .z2 to

I.D.a2688.b1.z2).

Table 616: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-2 of table Z (compounds I.D.a1.b4.z2 to

I.D.a2688.b4.z2).

Table 617: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-2 of table Z (compounds I.D.al .b19.z2 to

I.D.a2688.b19.z2).

Table 618: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-3 of table Z (compounds I.D.al .b1 .z3 to

I.D.a2688.b1.z3).

Table 619: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-3 of table Z (compounds I.D.a1.b4.z3 to

I.D.a2688.b4.z3).

Table 620: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-3 of table Z (compounds I.D.al .b19.z3 to

I.D.a2688.b19.z3).

Table 621 : Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-4 of table Z (compounds I.D.al .b1 .z4 to

I.D.a2688.b1.z4).

Table 622: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-4 of table Z (compounds I.D.a1.b4.z4 to

I.D.a2688.b4.z4).

Table 623: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-4 of table Z (compounds I.D.al .b19.z4 to

I.D.a2688.b19.z4).

Table 624: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-5 of table Z (compounds I.D.al .b1 .z5 to

I.D.a2688.b1.z5).

Table 625: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-5 of table Z (compounds I.D.a1.b4.z5 to

I.D.a2688.b4.z5).

Table 626: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-5 of table Z (compounds I.D.al .b19.z5 to

I.D.a2688.b19.z5).

Table 627: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-6 of table Z (compounds I.D.al .b1 .z6 to

I.D.a2688.b1.z6). Table 628: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-6 of table Z (compounds I.D.al .b4.z6 to

I.D.a2688.b4.z6).

Table 629: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-6 of table Z (compounds I.D.al .b19.z6 to

I.D.a2688.b19.z6).

Table 630: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-7 of table Z (compounds I.D.al .b1 .z7 to

I.D.a2688.b1.z7).

Table 631 : Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-7 of table Z (compounds I.D.al .b4.z7 to

I.D.a2688.b4.z7).

Table 632: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-7 of table Z (compounds I.D.al .b19.z7 to

I.D.a2688.b19.z7).

Table 633: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-8 of table Z (compounds I.D.al .b1 .z8 to

I.D.a2688.b1.z8).

Table 634: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-8 of table Z (compounds I.D.a1.b4.z8 to

I.D.a2688.b4.z8).

Table 635: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-8 of table Z (compounds I.D.al .b19.z8 to

I.D.a2688.b19.z8).

Table 636: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-9 of table Z (compounds I.D.al .b1 .z9 to

I.D.a2688.b1.z9).

Table 637: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-9 of table Z (compounds I.D.a1.b4.z9 to

I.D.a2688.b4.z9).

Table 638: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-9 of table Z (compounds I.D.al .b19.z9 to

I.D.a2688.b19.z9).

Table 639: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-10 of table Z (compounds I.D.al .b1.z10 to I.D.a2688.b1.z10).

Table 640: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-10 of table Z (compounds I.D.al .b4.z10 to I.D.a2688.b4.z10).

Table 641 : Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-10 of table Z (compounds I.D.a1.b19.z10 to

I.D.a2688.b19.z10).

Table 642: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-1 1 of table Z (compounds I.D.al .b1.z1 1 to

I.D.a2688.b1 .z1 1 ).

Table 643: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-1 1 of table Z (compounds I.D.al .b4.z1 1 to I.D.a2688.b4.z1 1 ).

Table 644: Compounds I.D , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-1 1 of table Z (compounds I.D.a1.b19.z1 1 to I.D.a2688.b19.z1 1 ). Table 645: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B (compounds I. E.a1.b1 to I.E.a672.b1 ).

Table 646: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-2 in Table B (compounds I. E.a1.b2 to I.E.a672.b2).

Table 647: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-3 in Table B (compounds I. E.a1.b3 to I.E.a672.b3).

Table 648: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B (compounds I. E.a1.b4 to I.E.a672.b4).

Table 649: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-5 in Table B (compounds I. E.a1 .b5 to I.E.a672.b5).

Table 650: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-6 in Table B (compounds I. E.a1.b6 to I.E.a672.b6).

Table 651 : Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-7 in Table B (compounds I. E.a1.b7 to I.E.a672.b7).

Table 652: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-8 in Table B (compounds I. E.a1.b8 to I.E.a672.b8).

Table 653: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-9 in Table B (compounds I. E.a1.b9 to I.E.a672.b9).

Table 654: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-10 in Table B (compounds I. E.a1.b10 to I.E.a672.b10).

Table 655: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 1 in Table B (compounds I. E.a1.b1 1 to I.E.a672.b1 1 ).

Table 656: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-12 in Table B (compounds I. E.a1.b12 to I.E.a672.b12).

Table 657: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-13 in Table B (compounds I. E.a1.b13 to l.E.a672.b13).

Table 658: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-14 in Table B (compounds I. E.a1.b14 to I.E.a672.b14).

Table 659: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-15 in Table B (compounds I. E.a1.b15 to I.E.a672.b15).

Table 660: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-16 in Table B (compounds I. E.a1.b16 to I.E.a672.b16).

Table 661 : Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-17 in Table B (compounds I. E.a1.b17 to I.E.a672.b17).

Table 662: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-18 in Table B (compounds I. E.a1.b18 to I.E.a672.b18).

Table 663: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B (compounds I. E.a1.b19 to I.E.a672.b19).

Table 664: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-20 in Table B (compounds I. E.a1.b20 to I.E.a672.b20).

Table 665: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-21 in Table B (compounds I. E.a1.b21 to I.E.a672.b21 ). Table 666: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-22 in Table B (compounds I. E.a1.b22 to I.E.a672.b22).

Table 667: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-23 in Table B (compounds I. E.a1.b23 to I.E.a672.b23).

Table 668: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-24 in Table B (compounds I. E.a1.b24 to I.E.a672.b24).

Table 669: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-25 in Table B (compounds I. E.a1.b25 to I.E.a672.b25).

Table 670: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-26 in Table B (compounds I. E.a1 .b26 to I.E.a672.b26).

Table 671 : Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-27 in Table B (compounds I. E.a1.b27 to I.E.a672.b27).

Table 672: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-28 in Table B (compounds I. E.a1.b28 to I.E.a672.b28).

Table 673: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-29 in Table B (compounds I. E.a1.b29 to I.E.a672.b29).

Table 674: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-30 in Table B (compounds I. E.a1.b30 to I.E.a672.b30).

Table 675: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-31 in Table B (compounds I. E.a1.b31 to I.E.a672.b31 ).

Table 676: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-32 in Table B (compounds I. E.a1.b32 to I.E.a672.b32).

Table 677: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-33 in Table B (compounds I. E.a1.b33 to I.E.a672.b33).

Table 678: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-34 in Table B (compounds I. E.a1.b34 to l.E.a672.b34).

Table 679: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-35 in Table B (compounds I. E.a1.b35 to I.E.a672.b35).

Table 680: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-36 in Table B (compounds I. E.a1.b36 to I.E.a672.b36).

Table 681 : Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-37 in Table B (compounds I. E.a1.b37 to I.E.a672.b37).

Table 682: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-38 in Table B (compounds I. E.a1.b38 to I.E.a672.b38).

Table 683: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-39 in Table B (compounds I. E.a1.b39 to I.E.a672.b39).

Table 684: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-40 in Table B (compounds I. E.a1.b40 to I.E.a672.b40).

Table 685: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-41 in Table B (compounds I. E.a1.b41 to I.E.a672.b41 ).

Table 686: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-42 in Table B (compounds I. E.a1.b42 to I.E.a672.b42). Table 687: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-43 in Table B (compounds I. E.a1.b43 to I.E.a672.b43).

Table 688: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-44 in Table B (compounds I. E.a1.b44 to I.E.a672.b44).

Table 689: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-45 in Table B (compounds I. E.a1 .b45 to I.E.a672.b45).

Table 690: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-46 in Table B (compounds I. E.a1.b46 to I.E.a672.b46).

Table 691 : Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-47 in Table B (compounds I. E.a1.b47 to I.E.a672.b47).

Table 692: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-48 in Table B (compounds I. E.a1.b48 to I.E.a672.b48).

Table 693: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-49 in Table B (compounds I. E.a1.b49 to I.E.a672.b49).

Table 694: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-50 in Table B (compounds I. E.a1.b50 to I.E.a672.b50).

Table 695: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-51 in Table B (compounds I. E.a1.b51 to I.E.a672.b51 ).

Table 696: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-52 in Table B (compounds I. E.a1.b52 to I.E.a672.b52).

Table 697: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-53 in Table B (compounds I. E.a1.b53 to I.E.a672.b53).

Table 698: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-54 in Table B (compounds I. E.a1.b54 to I.E.a672.b54).

Table 699: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-55 in Table B (compounds I. E.a1.b55 to l.E.a672.b55).

Table 700: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-56 in Table B (compounds I. E.a1.b56 to I.E.a672.b56).

Table 701 : Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-57 in Table B (compounds I. E.a1.b57 to I.E.a672.b57).

Table 702: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-58 in Table B (compounds I. E.a1.b58 to I.E.a672.b58).

Table 703: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-59 in Table B (compounds I. E.a1.b59 to I.E.a672.b59).

Table 704: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-60 in Table B (compounds I. E.a1.b60 to I.E.a672.b60).

Table 705: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-61 in Table B (compounds I. E.a1.b61 to I.E.a672.b61 ).

Table 706: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-62 in Table B (compounds I. E.a1.b62 to I.E.a672.b62).

Table 707: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-63 in Table B (compounds I. E.a1.b63 to I.E.a672.b63). Table 708: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-64 in Table B (compounds I. E.a1.b64 to I.E.a672.b64).

Table 709: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-65 in Table B (compounds I. E.a1 .b65 to I.E.a672.b65).

Table 710: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-66 in Table B (compounds I. E.a1.b66 to I.E.a672.b66).

Table 71 1 : Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-67 in Table B (compounds I. E.a1.b67 to I.E.a672.b67).

Table 712: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-68 in Table B (compounds I. E.a1.b68 to I.E.a672.b68).

Table 713: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-69 in Table B (compounds I. E.a1.b69 to I.E.a672.b69).

Table 714: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-70 in Table B (compounds I. E.a1.b70 to I.E.a672.b70).

Table 715: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-71 in Table B (compounds I. E.a1.b71 to I.E.a672.b71 ).

Table 716: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-72 in Table B (compounds I. E.a1.b72 to I.E.a672.b72).

Table 717: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-73 in Table B (compounds I. E.a1.b73 to I.E.a672.b73).

Table 718: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-74 in Table B (compounds I. E.a1.b74 to I.E.a672.b74).

Table 719: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-75 in Table B (compounds I. E.a1.b75 to I.E.a672.b75).

Table 720: Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-76 in Table B (compounds I. E.a1.b76 to l.E.a672.b76).

Table 721 : Compounds I.E , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-77 in Table B (compounds I. E.a1.b77 to I.E.a672.b77).

Table 722: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 of table C (compounds I.E.a1 .b1 .c1 to I.E.a2688.b1 .d ).

Table 723: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 of table C (compounds I.E.a1 .b4.c1 to I.E.a2688.b4.c1 ).

Table 724: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 of table C (compounds I.E.a1 .b19.c1 to I.E.a2688.b19.c1 ).

Table 725: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-2 of table C (compounds I.E.a1 .b1 .c2 to I.E.a2688.b1 .c2).

Table 726: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-2 of table C (compounds I.E.a1 .b4.c2 to I.E.a2688.b4.c2).

Table 727: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-2 of table C (compounds I.E.a1 .b19.c2 to I.E.a2688.b19.c2).

Table 728: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-3 of table C (compounds I.E.a1 .b1 .c3 to I.E.a2688.b1 .c3).

Table 729: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-3 of table C (compounds I.E.a1 .b4.c3 to I.E.a2688.b4.c3).

Table 730: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-3 of table C (compounds I.E.a1 .b19.c3 to I.E.a2688.b19.c3).

Table 731 : Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-4 of table C (compounds I.E.a1 .b1 .c4 to I.E.a2688.b1 .c4).

Table 732: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-4 of table C (compounds I.E.a1 .b4.c4 to I.E.a2688.b4.c4).

Table 733: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-4 of table C (compounds I.E.a1 .b19.c4 to I.E.a2688.b19.c4).

Table 734: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-5 of table C (compounds I.E.a1 .b1 .c5 to I.E.a2688.b1 .c5).

Table 735: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-5 of table C (compounds I.E.a1 .b4.c5 to I.E.a2688.b4.c5). Table 736: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-5 of table C (compounds I.E.a1 .b19.c5 to I.E.a2688.b19.c5).

Table 737: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-6 of table C (compounds I.E.a1 .b1 .c6 to I.E.a2688.b1 .c6).

Table 738: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-6 of table C (compounds I.E.a1 .b4.c6 to I.E.a2688.b4.c6).

Table 739: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-6 of table C (compounds I.E.a1 .b19.c6 to I.E.a2688.b19.c6).

Table 740: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-7 of table C (compounds I.E.al .b1 .c7 to I.E.a2688.b1 .c7).

Table 741 : Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-7 of table C (compounds I.E.a1.b4.c7 to I.E.a2688.b4.c7).

Table 742: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-7 of table C (compounds I.E.al .b19.c7 to I.E.a2688.b19.c7).

Table 743: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-8 of table C (compounds I.E.al .b1 .c8 to I.E.a2688.b1 .c8).

Table 744: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-8 of table C (compounds I.E.a1 .b4.c8 to I.E.a2688.b4.c8).

Table 745: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-8 of table C (compounds I.E.a1 .b19.c8 to I.E.a2688.b19.c8).

Table 746: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-9 of table C (compounds I.E.a1 .b1 .c9 to I.E.a2688.b1 .c9).

Table 747: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-9 of table C (compounds I.E.a1 .b4.c9 to I.E.a2688.b4.c9).

Table 748: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-9 of table C (compounds I.E.a1 .b19.c9 to I.E.a2688.b19.c9).

Table 749: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-10 of table C (compounds I.E.al .b1 .c10 to I.E.a2688.b1.c10).

Table 750: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-10 of table C (compounds I.E.al .b4.c10 to I.E.a2688.b4.c10).

Table 751 : Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-10 of table C (compounds I.E.a1 .b19.c10 to I.E.a2688.b19.c10).

Table 752: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 1 of table C (compounds I.E.a1 .b1 .c1 1 to I.E.a2688.b1.c1 1 ). Table 753: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 1 of table C (compounds I.E.a1 .b4.c1 1 to I.E.a2688.b4.c1 1 ).

Table 754: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 1 of table C (compounds I.E.a1 .b19.c1 1 to I.E.a2688.b19.c1 1 ).

Table 755: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-12 of table C (compounds I.E.a1.b1 .c12 to I.E.a2688.b1.c12).

Table 756: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-12 of table C (compounds I.E.al .b4.c12 to I.E.a2688.b4.c12).

Table 757: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-12 of table C (compounds I.E.a1 .b19.c12 to I.E.a2688.b19.c12).

Table 758: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-13 of table C (compounds I.E.a1 .b1 .c13 to I.E.a2688.b1.c13).

Table 759: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-13 of table C (compounds I.E.al .b4.c13 to I.E.a2688.b4.c13).

Table 760: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-13 of table C (compounds I.E.a1 .b19.c13 to I.E.a2688.b19.c13).

Table 761 : Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-14 of table C (compounds I.E.al .b1 .c14 to I.E.a2688.b1.c14).

Table 762: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-14 of table C (compounds I.E.a1.b4.c14 to I.E.a2688.b4.c14).

Table 763: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-14 of table C (compounds I.E.a1 .b19.c14 to I.E.a2688.b19.c14).

Table 764: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-15 of table C (compounds I.E.al .b1 .c15 to I.E.a2688.b1.c15).

Table 765: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-15 of table C (compounds I.E.al .b4.c15 to I.E.a2688.b4.c15).

Table 766: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-15 of table C (compounds I.E.a1 .b19.c15 to I.E.a2688.b19.c15).

Table 767: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-16 of table C (compounds I.E.al .b1 .c16 to I.E.a2688.b1.c16).

Table 768: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-16 of table C (compounds I.E.a1 .b4.c16 to I.E.a2688.b4.c16).

Table 769: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-16 of table C (compounds I.E.a1 .b19.c16 to I.E.a2688.b19.c16). Table 770: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-17 of table C (compounds I.E.a1 .b1 .c17 to I.E.a2688.b1.c17).

Table 771 : Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-17 of table C (compounds I.E.a1 .b4.c17 to I.E.a2688.b4.c17).

Table 772: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-17 of table C (compounds I.E.a1 .b19.c17 to I.E.a2688.b19.c17).

Table 773: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-1 of table Z (compounds I.E.al .b1 .z1 to

I.E.a2688.b1.z1 ).

Table 774: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-1 of table Z (compounds I.E.al .b4.z1 to

I.E.a2688.b4.z1 ).

Table 775: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-1 of table Z (compounds I.E.al .b19.z1 to

I.E.a2688.b19.z1 ).

Table 776: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-2 of table Z (compounds I.E.al .b1 .z2 to

I.E.a2688.b1.z2).

Table 777: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-2 of table Z (compounds I.E.a1.b4.z2 to

I.E.a2688.b4.z2).

Table 778: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-2 of table Z (compounds I.E.al .b19.z2 to

I.E.a2688.b19.z2).

Table 779: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-3 of table Z (compounds I.E.al .b1 .z3 to

I.E.a2688.b1.z3).

Table 780: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-3 of table Z (compounds I.E.a1.b4.z3 to

I.E.a2688.b4.z3).

Table 781 : Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-3 of table Z (compounds I.E.al .b19.z3 to

I.E.a2688.b19.z3).

Table 782: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-4 of table Z (compounds I.E.al .b1 .z4 to

I.E.a2688.b1 .z4).

Table 783: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-4 of table Z (compounds I.E.a1.b4.z4 to

I.E.a2688.b4.z4).

Table 784: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-4 of table Z (compounds I.E.al .b19.z4 to

I.E.a2688.b19.z4).

Table 785: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-5 of table Z (compounds I.E.al .b1.z5 to

I.E.a2688.b1.z5).

Table 786: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-5 of table Z (compounds I.E.a1.b4.z5 to

I.E.a2688.b4.z5). Table 787: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-5 of table Z (compounds I.E.al .b19.z5 to

I.E.a2688.b19.z5).

Table 788: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-6 of table Z (compounds I.E.al .b1 .z6 to

I.E.a2688.b1.z6).

Table 789: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-6 of table Z (compounds I.E.a1.b4.z6 to

I.E.a2688.b4.z6).

Table 790: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-6 of table Z (compounds I.E.al .b19.z6 to

I.E.a2688.b19.z6).

Table 791 : Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-7 of table Z (compounds I.E.al .b1 .z7 to

I.E.a2688.b1.z7).

Table 792: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-7 of table Z (compounds I.E.a1.b4.z7 to

I.E.a2688.b4.z7).

Table 793: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-7 of table Z (compounds I.E.al .b19.z7 to

I.E.a2688.b19.z7).

Table 794: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-8 of table Z (compounds I.E.al .b1 .z8 to

I.E.a2688.b1.z8).

Table 795: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-8 of table Z (compounds I.E.a1.b4.z8 to

I.E.a2688.b4.z8).

Table 796: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-8 of table Z (compounds I.E.al .b19.z8 to

I.E.a2688.b19.z8).

Table 797: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-9 of table Z (compounds I.E.al .b1 .z9 to

I.E.a2688.b1.z9).

Table 798: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-9 of table Z (compounds I.E.a1.b4.z9 to

I.E.a2688.b4.z9).

Table 799: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-9 of table Z (compounds I.E.al .b19.z9 to

I.E.a2688.b19.z9).

Table 800: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-10 of table Z (compounds I.E.al .b1.z10 to I.E.a2688.b1 .z10).

Table 801 : Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-10 of table Z (compounds I.E.al .b4.z10 to I.E.a2688.b4.z10).

Table 802: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-10 of table Z (compounds I.E.a1.b19.z10 to

I.E.a2688.b19.z10).

Table 803: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-1 1 of table Z (compounds I.E.al .b1.z1 1 to

I.E.a2688.b1 .z1 1 ). Table 804: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-1 1 of table Z (compounds I.E.al .b4.z1 1 to I.E.a2688.b4.z1 1 ).

Table 805: Compounds I.E , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-1 1 of table Z (compounds I.E.a1.b19.z1 1 to I.E.a2688.b19.z1 1 ).

Table 806: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B (compounds I. F.a1 .b1 to I.F.a672.b1 ).

Table 807: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-2 in Table B (compounds I. F.a1 .b2 to I.F.a672.b2).

Table 808: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-3 in Table B (compounds I. F.a1 .b3 to I.F.a672.b3).

Table 809: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B (compounds I. F.a1 .b4 to I.F.a672.b4).

Table 810: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-5 in Table B (compounds I. F.a1 .b5 to I.F.a672.b5).

Table 81 1 : Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-6 in Table B (compounds I. F.a1 .b6 to I.F.a672.b6).

Table 812: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-7 in Table B (compounds I. F.a1 .b7 to I.F.a672.b7).

Table 813: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-8 in Table B (compounds I. F.a1 .b8 to I.F.a672.b8). Table 814: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-9 in Table B (compounds I. F.a1 .b9 to I.F.a672.b9).

Table 815: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-10 in Table B (compounds I. F.a1 .b10 to I.F.a672.b10).

Table 816: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 1 in Table B (compounds I. F.a1 .b1 1 to I.F.a672.b1 1 ).

Table 817: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-12 in Table B (compounds I. F.a1 .b12 to I.F.a672.b12).

Table 818: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-13 in Table B (compounds I. F.a1 .b13 to I.F.a672.b13).

Table 819: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-14 in Table B (compounds I. F.a1 .b14 to I.F.a672.b14).

Table 820: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-15 in Table B (compounds I. F.a1 .b15 to I.F.a672.b15).

Table 821 : Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-16 in Table B (compounds I. F.a1 .b16 to I.F.a672.b16).

Table 822: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-17 in Table B (compounds I. F.a1 .b17 to I.F.a672.b17).

Table 823: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-18 in Table B (compounds I. F.a1 .b18 to I.F.a672.b18).

Table 824: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B (compounds I. F.a1 .b19 to I.F.a672.b19).

Table 825: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-20 in Table B (compounds I. F.a1 .b20 to I.F.a672.b20).

Table 826: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-21 in Table B (compounds I. F.a1 .b21 to I.F.a672.b21 ).

Table 827: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-22 in Table B (compounds I. F.a1 .b22 to I.F.a672.b22).

Table 828: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-23 in Table B (compounds I. F.a1 .b23 to I.F.a672.b23).

Table 829: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-24 in Table B (compounds I. F.a1 .b24 to I.F.a672.b24).

Table 830: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-25 in Table B (compounds I. F.a1 .b25 to I.F.a672.b25).

Table 831 : Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-26 in Table B (compounds I. F.a1 .b26 to I.F.a672.b26).

Table 832: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-27 in Table B (compounds I. F.a1 .b27 to I.F.a672.b27).

Table 833: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-28 in Table B (compounds I. F.a1 .b28 to I.F.a672.b28).

Table 834: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-29 in Table B (compounds I. F.a1 .b29 to I.F.a672.b29). Table 835: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-30 in Table B (compounds I. F.a1 .b30 to I.F.a672.b30).

Table 836: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-31 in Table B (compounds I. F.a1 .b31 to I.F.a672.b31 ).

Table 837: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-32 in Table B (compounds I. F.a1 .b32 to I.F.a672.b32).

Table 838: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-33 in Table B (compounds I. F.a1 .b33 to I.F.a672.b33).

Table 839: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-34 in Table B (compounds I. F.a1 .b34 to I.F.a672.b34).

Table 840: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-35 in Table B (compounds I. F.a1 .b35 to I.F.a672.b35).

Table 841 : Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-36 in Table B (compounds I. F.a1 .b36 to I.F.a672.b36).

Table 842: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-37 in Table B (compounds I. F.a1 .b37 to I.F.a672.b37).

Table 843: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-38 in Table B (compounds I. F.a1 .b38 to I.F.a672.b38).

Table 844: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-39 in Table B (compounds I. F.a1 .b39 to I.F.a672.b39).

Table 845: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-40 in Table B (compounds I. F.al .MO to I.F.a672.b40).

Table 846: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-41 in Table B (compounds I. F.a1 .b41 to I.F.a672.b41 ).

Table 847: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-42 in Table B (compounds I. F.a1 .b42 to l.F.a672.b42).

Table 848: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-43 in Table B (compounds I. F.a1 .b43 to I.F.a672.b43).

Table 849: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-44 in Table B (compounds I. F.a1 .b44 to I.F.a672.b44).

Table 850: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-45 in Table B (compounds I. F.a1 .b45 to I.F.a672.b45).

Table 851 : Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-46 in Table B (compounds I. F.a1 .b46 to I.F.a672.b46).

Table 852: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-47 in Table B (compounds I. F.a1 .b47 to I.F.a672.b47).

Table 853: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-48 in Table B (compounds I. F.a1 .b48 to I.F.a672.b48).

Table 854: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-49 in Table B (compounds I. F.a1 .b49 to I.F.a672.b49).

Table 855: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-50 in Table B (compounds I. F.a1 .b50 to I.F.a672.b50). Table 856: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-51 in Table B (compounds I. F.a1 .b51 to I.F.a672.b51 ).

Table 857: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-52 in Table B (compounds I. F.a1 .b52 to I.F.a672.b52).

Table 858: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-53 in Table B (compounds I. F.a1 .b53 to I.F.a672.b53).

Table 859: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-54 in Table B (compounds I. F.a1 .b54 to I.F.a672.b54).

Table 860: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-55 in Table B (compounds I. F.a1 .b55 to I.F.a672.b55).

Table 861 : Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-56 in Table B (compounds I. F.a1 .b56 to I.F.a672.b56).

Table 862: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-57 in Table B (compounds I. F.a1 .b57 to I.F.a672.b57).

Table 863: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-58 in Table B (compounds I. F.a1 .b58 to I.F.a672.b58).

Table 864: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-59 in Table B (compounds I. F.a1 .b59 to I.F.a672.b59).

Table 865: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-60 in Table B (compounds I. F.a1 .b60 to I.F.a672.b60).

Table 866: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-61 in Table B (compounds I. F.a1 .b61 to I.F.a672.b61 ).

Table 867: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-62 in Table B (compounds I. F.a1 .b62 to I.F.a672.b62).

Table 868: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-63 in Table B (compounds I. F.a1 .b63 to l.F.a672.b63).

Table 869: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-64 in Table B (compounds I. F.a1 .b64 to I.F.a672.b64).

Table 870: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-65 in Table B (compounds I. F.a1 .b65 to I.F.a672.b65).

Table 871 : Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-66 in Table B (compounds I. F.a1 .b66 to I.F.a672.b66).

Table 872: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-67 in Table B (compounds I. F.a1 .b67 to I.F.a672.b67).

Table 873: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-68 in Table B (compounds I. F.a1 .b68 to I.F.a672.b68).

Table 874: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-69 in Table B (compounds I. F.a1 .b69 to I.F.a672.b69).

Table 875: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-70 in Table B (compounds I. F.a1 .b70 to I.F.a672.b70).

Table 876: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-71 in Table B (compounds I. F.a1 .b71 to I.F.a672.b71 ). Table 877: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-72 in Table B (compounds I. F.a1 .b72 to I.F.a672.b72).

Table 878: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-73 in Table B (compounds I. F.a1 .b73 to I.F.a672.b73).

Table 879: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-74 in Table B (compounds I. F.a1 .b74 to I.F.a672.b74).

Table 880: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-75 in Table B (compounds I. F.a1 .b75 to I.F.a672.b75).

Table 881 : Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-76 in Table B (compounds I. F.a1 .b76 to I.F.a672.b76).

Table 882: Compounds I.F , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-77 in Table B (compounds I. F.a1.b77 to I.F.a672.b77).

Table 883: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 of table C (compounds I.F.a1.b1.c1 to I.F.a2688.b1 .d ).

Table 884: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 of table C (compounds I.F.a1.b4.c1 to I.F.a2688.b4.c1 ).

Table 885: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 of table C (compounds I.F.a1.b19.c1 to I.F.a2688.b19.c1 ).

Table 886: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-2 of table C (compounds I.F.a1.b1.c2 to I.F.a2688.b1 .c2).

Table 887: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-2 of table C (compounds I.F.a1.b4.c2 to I.F.a2688.b4.c2).

Table 888: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-2 of table C (compounds I.F.a1.b19.c2 to I.F.a2688.b19.c2).

Table 889: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-3 of table C (compounds I.F.a1.b1.c3 to I.F.a2688.b1 .c3).

Table 890: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-3 of table C (compounds I.F.a1.b4.c3 to I.F.a2688.b4.c3).

Table 891 : Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-3 of table C (compounds I.F.a1.b19.c3 to I.F.a2688.b19.c3).

Table 892: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-4 of table C (compounds I.F.al .b1.c4 to I.F.a2688.b1 .c4).

Table 893: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-4 of table C (compounds I.F.a1.b4.c4 to I.F.a2688.b4.c4).

Table 894: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-4 of table C (compounds I.F.a1.b19.c4 to I.F.a2688.b19.c4). Table 895: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-5 of table C (compounds I.F.al .b1.c5 to I.F.a2688.b1 .c5).

Table 896: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-5 of table C (compounds I.F.a1.b4.c5 to I.F.a2688.b4.c5).

Table 897: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-5 of table C (compounds I.F.a1.b19.c5 to I.F.a2688.b19.c5).

Table 898: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-6 of table C (compounds I.F.al .b1.c6 to I.F.a2688.b1 .c6).

Table 899: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-6 of table C (compounds I.F.al .b4.c6 to I.F.a2688.b4.c6).

Table 900: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-6 of table C (compounds I.F.a1.b19.c6 to I.F.a2688.b19.c6).

Table 901 : Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-7 of table C (compounds I.F.al .b1 .c7 to I.F.a2688.b1 .c7).

Table 902: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-7 of table C (compounds I.F.al .b4.c7 to I.F.a2688.b4.c7).

Table 903: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-7 of table C (compounds I.F.a1.b19.c7 to I.F.a2688.b19.c7).

Table 904: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-8 of table C (compounds I.F.a1.b1.c8 to I.F.a2688.b1 .c8).

Table 905: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-8 of table C (compounds I.F.a1.b4.c8 to I.F.a2688.b4.c8).

Table 906: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-8 of table C (compounds I.F.a1.b19.c8 to I.F.a2688.b19.c8).

Table 907: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-9 of table C (compounds I.F.a1.b1.c9 to I.F.a2688.b1 .c9).

Table 908: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-9 of table C (compounds I.F.a1.b4.c9 to I.F.a2688.b4.c9).

Table 909: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-9 of table C (compounds I.F.a1.b19.c9 to I.F.a2688.b19.c9).

Table 910: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-10 of table C (compounds I.F.a1.b1.c10 to I.F.a2688.b1.c10).

Table 91 1 : Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-10 of table C (compounds I.F.a1.b4.c10 to I.F.a2688.b4.c10). Table 912: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-10 of table C (compounds I.F.a1.b19.c10 to I.F.a2688.b19.c10).

Table 913: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 1 of table C (compounds I.F.a1.b1.c1 1 to I.F.a2688.b1.c1 1 ).

Table 914: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 1 of table C (compounds I.F.a1.b4.c1 1 to I.F.a2688.b4.c1 1 ).

Table 915: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 1 of table C (compounds I.F.a1.b19.c1 1 to I.F.a2688.b19.c1 1 ).

Table 916: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-12 of table C (compounds I.F.a1.b1.c12 to I.F.a2688.b1.c12).

Table 917: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-12 of table C (compounds I.F.al .b4.c12 to I.F.a2688.b4.c12).

Table 918: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-12 of table C (compounds I.F.a1.b19.c12 to I.F.a2688.b19.c12).

Table 919: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-13 of table C (compounds I.F.a1.b1.c13 to I.F.a2688.b1.c13).

Table 920: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-13 of table C (compounds I.F.a1.b4.c13 to I.F.a2688.b4.c13).

Table 921 : Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-13 of table C (compounds I.F.a1.b19.c13 to I.F.a2688.b19.c13).

Table 922: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-14 of table C (compounds I.F.al .b1 .c14 to I.F.a2688.b1.c14).

Table 923: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-14 of table C (compounds I.F.a1.b4.c14 to I.F.a2688.b4.c14).

Table 924: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-14 of table C (compounds I.F.a1.b19.c14 to I.F.a2688.b19.c14).

Table 925: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-15 of table C (compounds I.F.a1.b1.c15 to I.F.a2688.b1.c15).

Table 926: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-15 of table C (compounds I.F.a1.b4.c15 to I.F.a2688.b4.c15).

Table 927: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-15 of table C (compounds I.F.a1.b19.c15 to I.F.a2688.b19.c15).

Table 928: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-16 of table C (compounds I.F.a1.b1.c16 to I.F.a2688.b1.c16). Table 929: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-16 of table C (compounds I.F.a1.b4.c16 to I.F.a2688.b4.c16).

Table 930: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-16 of table C (compounds I.F.a1.b19.c16 to I.F.a2688.b19.c16).

Table 931 : Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-17 of table C (compounds I.F.a1.b1.c17 to I.F.a2688.b1.c17).

Table 932: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-17 of table C (compounds I.F.a1.b4.c17 to I.F.a2688.b4.c17).

Table 933: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-17 of table C (compounds I.F.a1.b19.c17 to I.F.a2688.b19.c17).

Table 934: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-1 of table Z (compounds I.F.al .b1 .z1 to

I.F.a2688.b1 .z1 ).

Table 935: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-1 of table Z (compounds I.F.al .b4.z1 to

I.F.a2688.b4.z1 ).

Table 936: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-1 of table Z (compounds I.F.al .b19.z1 to

I.F.a2688.b19.z1 ).

Table 937: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-2 of table Z (compounds I.F.al .b1 .z2 to

I.F.a2688.b1 .z2).

Table 938: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-2 of table Z (compounds I.F.a1.b4.z2 to

I.F.a2688.b4.z2).

Table 939: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-2 of table Z (compounds I.F.al .b19.z2 to

I.F.a2688.b19.z2).

Table 940: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-3 of table Z (compounds I.F.al .b1 .z3 to

I.F.a2688.b1 .z3).

Table 941 : Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-3 of table Z (compounds I.F.a1.b4.z3 to

I.F.a2688.b4.z3).

Table 942: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-3 of table Z (compounds I.F.a1.b19.z3 to

I.F.a2688.b19.z3).

Table 943: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-4 of table Z (compounds I.F.al .b1 .z4 to

I.F.a2688.b1 .z4).

Table 944: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-4 of table Z (compounds I.F.a1.b4.z4 to

I.F.a2688.b4.z4).

Table 945: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-4 of table Z (compounds I.F.a1.b19.z4 to

I.F.a2688.b19.z4). Table 946: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-5 of table Z (compounds I.F.al .b1 .z5 to

I.F.a2688.b1 .z5).

Table 947: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-5 of table Z (compounds I.F.a1.b4.z5 to

I.F.a2688.b4.z5).

Table 948: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-5 of table Z (compounds I.F.al .b19.z5 to

I.F.a2688.b19.z5).

Table 949: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-6 of table Z (compounds I.F.al .b1 .z6 to

I.F.a2688.b1 .z6).

Table 950: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-6 of table Z (compounds I.F.a1.b4.z6 to

I.F.a2688.b4.z6).

Table 951 : Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-6 of table Z (compounds I.F.al .b19.z6 to

I.F.a2688.b19.z6).

Table 952: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-7 of table Z (compounds I.F.al .b1 .z7 to

I.F.a2688.b1 .z7).

Table 953: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-7 of table Z (compounds I.F.a1.b4.z7 to

I.F.a2688.b4.z7).

Table 954: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-7 of table Z (compounds I.F.al .b19.z7 to

I.F.a2688.b19.z7).

Table 955: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-8 of table Z (compounds I.F.al .b1 .z8 to

I.F.a2688.b1 .z8).

Table 956: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-8 of table Z (compounds I.F.a1.b4.z8 to

I.F.a2688.b4.z8).

Table 957: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-8 of table Z (compounds I.F.al .b19.z8 to

I.F.a2688.b19.z8).

Table 958: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-9 of table Z (compounds I.F.al .b1 .z9 to

I.F.a2688.b1 .z9).

Table 959: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-9 of table Z (compounds I.F.a1.b4.z9 to

I.F.a2688.b4.z9).

Table 960: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-9 of table Z (compounds I.F.al .b19.z9 to

I.F.a2688.b19.z9).

Table 961 : Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-10 of table Z (compounds I.F.al .b1.z10 to I.F.a2688.b1 .z10).

Table 962: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-10 of table Z (compounds I.F.al .b4.z10 to I.F.a2688.b4.z10). Table 963: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-10 of table Z (compounds I.F.a1.b19.z10 to I.F.a2688.b19.z10).

Table 964: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-1 1 of table Z (compounds I.F.al .b1.z1 1 to I.F.a2688.b1 .z1 1 ).

Table 965: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-1 1 of table Z (compounds I.F.al .b4.z1 1 to I.F.a2688.b4.z1 1 ).

Table 966: Compounds I.F , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-1 1 of table Z (compounds I.F.a1.b19.z1 1 to I.F.a2688.b19.z1 1 ).

Table 967: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B (compounds I. G.a1 .b1 to I.G.a672.b1 ).

Table 968: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-2 in Table B (compounds I. G.a1 .b2 to I.G.a672.b2).

Table 969: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-3 in Table B (compounds I. G.a1 .b3 to I.G.a672.b3).

Table 970: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B (compounds I. G.a1 .b4 to I.G.a672.b4).

Table 971 : Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-5 in Table B (compounds I. G.a1 .b5 to I.G.a672.b5).

Table 972: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-6 in Table B (compounds I. G.a1 .b6 to I.G.a672.b6).

Table 973: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-7 in Table B (compounds I. G.a1 .b7 to I.G.a672.b7).

Table 974: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-8 in Table B (compounds I. G.a1 .b8 to l.G.a672.b8).

Table 975: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-9 in Table B (compounds I. G.a1 .b9 to I.G.a672.b9).

Table 976: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-10 in Table B (compounds I. G.a1 .b10 to I.G.a672.b10).

Table 977: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 1 in Table B (compounds I. G.a1 .b1 1 to I.G.a672.b1 1 ).

Table 978: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-12 in Table B (compounds I. G.a1 .b12 to I.G.a672.b12).

Table 979: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-13 in Table B (compounds I. G.a1 .b13 to I.G.a672.b13).

Table 980: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-14 in Table B (compounds I. G.a1 .b14 to I.G.a672.b14).

Table 981 : Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-15 in Table B (compounds I. G.a1 .b15 to I.G.a672.b15).

Table 982: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-16 in Table B (compounds I. G.a1 .b16 to I.G.a672.b16). Table 983: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-17 in Table B (compounds I. G.a1 .b17 to I.G.a672.b17).

Table 984: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-18 in Table B (compounds I. G.a1 .b18 to I.G.a672.b18).

Table 985: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B (compounds I. G.a1 .b19 to I.G.a672.b19).

Table 986: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-20 in Table B (compounds I. G.a1 .b20 to I.G.a672.b20).

Table 987: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-21 in Table B (compounds I. G.a1 .b21 to I.G.a672.b21 ).

Table 988: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-22 in Table B (compounds I. G.a1 .b22 to I.G.a672.b22).

Table 989: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-23 in Table B (compounds I. G.a1 .b23 to I.G.a672.b23).

Table 990: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-24 in Table B (compounds I. G.a1 .b24 to I.G.a672.b24).

Table 991 : Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-25 in Table B (compounds I. G.a1 .b25 to I.G.a672.b25).

Table 992: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-26 in Table B (compounds I. G.a1 .b26 to I.G.a672.b26).

Table 993: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-27 in Table B (compounds I. G.a1 .b27 to I.G.a672.b27).

Table 994: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-28 in Table B (compounds I. G.a1 .b28 to I.G.a672.b28).

Table 995: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-29 in Table B (compounds I. G.a1 .b29 to l.G.a672.b29).

Table 996: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-30 in Table B (compounds I. G.a1 .b30 to I.G.a672.b30).

Table 997: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-31 in Table B (compounds I. G.a1 .b31 to I.G.a672.b31 ).

Table 998: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-32 in Table B (compounds I. G.a1 .b32 to I.G.a672.b32).

Table 999: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-33 in Table B (compounds I. G.a1 .b33 to I.G.a672.b33).

Table 1000: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-34 in Table B (compounds I. G.a1 .b34 to I.G.a672.b34).

Table 1001 : Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-35 in Table B (compounds I. G.a1 .b35 to I.G.a672.b35).

Table 1002: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-36 in Table B (compounds I. G.a1 .b36 to I.G.a672.b36).

Table 1003: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-37 in Table B (compounds I. G.a1 .b37 to I.G.a672.b37). Table 1004: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-38 in Table B (compounds I. G.a1 .b38 to I.G.a672.b38).

Table 1005: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-39 in Table B (compounds I. G.a1 .b39 to I.G.a672.b39).

Table 1006: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-40 in Table B (compounds I. G.a1 .b40 to I.G.a672.b40).

Table 1007: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-41 in Table B (compounds I. G.a1 .b41 to I.G.a672.b41 ).

Table 1008: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-42 in Table B (compounds I. G.a1 .b42 to I.G.a672.b42).

Table 1009: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-43 in Table B (compounds I. G.a1 .b43 to I.G.a672.b43).

Table 1010: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-44 in Table B (compounds I. G.a1 .b44 to I.G.a672.b44).

Table 101 1 : Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-45 in Table B (compounds I. G.a1 .b45 to I.G.a672.b45).

Table 1012: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-46 in Table B (compounds I. G.a1 .b46 to I.G.a672.b46).

Table 1013: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-47 in Table B (compounds I. G.a1 .b47 to I.G.a672.b47).

Table 1014: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-48 in Table B (compounds I. G.a1 .b48 to I.G.a672.b48).

Table 1015: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-49 in Table B (compounds I. G.a1 .b49 to I.G.a672.b49).

Table 1016: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-50 in Table B (compounds I. G.a1 .b50 to I.G.a672.b50).

Table 1017: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-51 in Table B (compounds I. G.a1 .b51 to I.G.a672.b51 ).

Table 1018: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-52 in Table B (compounds I. G.a1 .b52 to I.G.a672.b52).

Table 1019: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-53 in Table B (compounds I. G.a1 .b53 to I.G.a672.b53).

Table 1020: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-54 in Table B (compounds I. G.a1 .b54 to I.G.a672.b54).

Table 1021 : Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-55 in Table B (compounds I. G.a1 .b55 to I.G.a672.b55).

Table 1022: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-56 in Table B (compounds I. G.a1 .b56 to I.G.a672.b56).

Table 1023: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-57 in Table B (compounds I. G.a1 .b57 to I.G.a672.b57).

Table 1024: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-58 in Table B (compounds I. G.a1 .b58 to I.G.a672.b58). Table 1025: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-59 in Table B (compounds I. G.a1 .b59 to I.G.a672.b59).

Table 1026: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-60 in Table B (compounds I. G.a1 .b60 to I.G.a672.b60).

Table 1027: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-61 in Table B (compounds I. G.a1 .b61 to I.G.a672.b61 ).

Table 1028: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-62 in Table B (compounds I. G.a1 .b62 to I.G.a672.b62).

Table 1029: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-63 in Table B (compounds I. G.a1 .b63 to I.G.a672.b63).

Table 1030: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-64 in Table B (compounds I. G.a1 .b64 to I.G.a672.b64).

Table 1031 : Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-65 in Table B (compounds I. G.a1 .b65 to I.G.a672.b65).

Table 1032: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-66 in Table B (compounds I. G.a1 .b66 to I.G.a672.b66).

Table 1033: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-67 in Table B (compounds I. G.a1 .b67 to I.G.a672.b67).

Table 1034: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-68 in Table B (compounds I. G.a1 .b68 to I.G.a672.b68).

Table 1035: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-69 in Table B (compounds I.

G.a1 .b69 to I.G.a672.b69).

Table 1036: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-70 in Table B (compounds I.

G.a1 .b70 to I.G.a672.b70).

Table 1037: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-71 in Table B (compounds I. G.a1 .b71 to I.G.a672.b71 ).

Table 1038: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-72 in Table B (compounds I.

G.a1 .b72 to I.G.a672.b72).

Table 1039: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-73 in Table B (compounds I.

G.a1 .b73 to I.G.a672.b73).

Table 1040: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-74 in Table B (compounds I.

G.a1 .b74 to I.G.a672.b74).

Table 1041 : Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-75 in Table B (compounds I.

G.a1 .b75 to I.G.a672.b75).

Table 1042: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-76 in Table B (compounds I. G.a1 .b76 to I.G.a672.b76).

Table 1043: Compounds I.G , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-77 in Table B (compounds I.

G.a1 .b77 to I.G.a672.b77).

Table 1044: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to

A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 of table C (compounds

I.G.a1.b1 .c1 to I.G.a2688.b1 .c1 ).

Table 1045: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to

A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 of table C (compounds I.G.a1 .b4.c1 to I.G.a2688.b4.c1 ).

Table 1046: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 of table C (compounds I.G.a1 .b19.c1 to I.G.a2688.b19.c1 ).

Table 1047: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-2 of table C (compounds I.G.al .b1 .c2 to I.G.a2688.b1 .c2).

Table 1048: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-2 of table C (compounds I.G.al . b4.c2 to I.G.a2688.b4.c2).

Table 1049: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-2 of table C (compounds I.G.al . b19.c2 to I.G.a2688.b19.c2).

Table 1050: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-3 of table C (compounds I.G.al .b1 .c3 to I.G.a2688.b1 .c3).

Table 1051 : Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-3 of table C (compounds I.G.al . b4.c3 to I.G.a2688.b4.c3).

Table 1052: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-3 of table C (compounds I.G.al . b19.c3 to I.G.a2688.b19.c3).

Table 1053: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-4 of table C (compounds I.G.al .b1 .c4 to I.G.a2688.b1 .c4). Table 1054: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-4 of table C (compounds I.G.al .b4.c4 to I.G.a2688.b4.c4).

Table 1055: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-4 of table C (compounds I.G.al . b19.c4 to I.G.a2688.b19.c4).

Table 1056: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-5 of table C (compounds I.G.al . b1 .c5 to I.G.a2688.b1 .c5).

Table 1057: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-5 of table C (compounds I.G.al .b4.c5 to I.G.a2688.b4.c5).

Table 1058: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-5 of table C (compounds I.G.al . b19.c5 to I.G.a2688.b19.c5).

Table 1059: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-6 of table C (compounds I.G.al .b1 .c6 to I.G.a2688.b1 .c6).

Table 1060: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-6 of table C (compounds I.G.al .b4.c6 to I.G.a2688.b4.c6).

Table 1061 : Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-6 of table C (compounds I.G.al . b19.c6 to I.G.a2688.b19.c6).

Table 1062: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-7 of table C (compounds I.G.al .b1 .c7 to I.G.a2688.b1 .c7).

Table 1063: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-7 of table C (compounds I.G.al .b4.c7 to I.G.a2688.b4.c7).

Table 1064: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-7 of table C (compounds I.G.al . b19.c7 to I.G.a2688.b19.c7).

Table 1065: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-8 of table C (compounds I.G.al .b1 .c8 to I.G.a2688.b1.c8).

Table 1066: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-8 of table C (compounds I.G.al .b4.c8 to I.G.a2688.b4.c8).

Table 1067: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-8 of table C (compounds I.G.al . b19.c8 to I.G.a2688.b19.c8).

Table 1068: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-9 of table C (compounds I.G.al .b1 .c9 to I.G.a2688.b1 .c9).

Table 1069: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-9 of table C (compounds I.G.al . b4.c9 to I.G.a2688.b4.c9).

Table 1070: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-9 of table C (compounds I.G.al . b19.c9 to I.G.a2688.b19.c9). Table 1071 : Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-10 of table C (compounds I.G.a1 .b1 .c10 to I.G.a2688.b1.c10).

Table 1072: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-10 of table C (compounds I.G.a1 .b4.c10 to I.G.a2688.b4.c10).

Table 1073: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-10 of table C (compounds I.G.a1 .b19.c10 to I.G.a2688.b19.c10).

Table 1074: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 1 of table C (compounds I.G.a1 .b1 .c1 1 to I.G.a2688.b1.c1 1 ).

Table 1075: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 1 of table C (compounds I.G.a1 .b4.c1 1 to I.G.a2688.b4.c1 1 ).

Table 1076: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 1 of table C (compounds I.G.a1 .b19.c1 1 to I.G.a2688.b19.c1 1 ).

Table 1077: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-12 of table C (compounds I.G.a1 .b1 .c12 to I.G.a2688.b1.c12).

Table 1078: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-12 of table C (compounds I.G.al .b4.c12 to I.G.a2688.b4.c12).

Table 1079: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-12 of table C (compounds I.G.a1 .b19.c12 to I.G.a2688.b19.c12).

Table 1080: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-13 of table C (compounds I.G.al .b1 .c13 to I.G.a2688.b1.c13).

Table 1081 : Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-13 of table C (compounds I.G.al . b4.c13 to I.G.a2688.b4.c13).

Table 1082: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-13 of table C (compounds I.G.al . b19.c13 to I.G.a2688.b19.c13).

Table 1083: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-14 of table C (compounds I.G.al .b1 .c14 to I.G.a2688.b1.c14).

Table 1084: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-14 of table C (compounds I.G.al .b4.c14 to I.G.a2688.b4.c14).

Table 1085: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-14 of table C (compounds I.G.al . b19.c14 to I.G.a2688.b19.c14).

Table 1086: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-15 of table C (compounds I.G.al .b1 .c15 to I.G.a2688.b1.c15).

Table 1087: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-15 of table C (compounds I.G.al . b4.c15 to I.G.a2688.b4.c15). Table 1088: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-15 of table C (compounds I.G.a1 .b19.c15 to I.G.a2688.b19.c15).

Table 1089: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-16 of table C (compounds I.G.a1 .b1 .c16 to I.G.a2688.b1.c16).

Table 1090: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-16 of table C (compounds I.G.a1 .b4.c16 to I.G.a2688.b4.c16).

Table 1091 : Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-16 of table C (compounds I.G.a1 .b19.c16 to I.G.a2688.b19.c16).

Table 1092: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-17 of table C (compounds I.G.a1 .b1 .c17 to I.G.a2688.b1.c17).

Table 1093: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-17 of table C (compounds I.G.a1 .b4.c17 to I.G.a2688.b4.c17).

Table 1094: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-17 of table C (compounds I.G.a1 .b19.c17 to I.G.a2688.b19.c17).

Table 1095: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-1 of table Z (compounds I.G.al .b1.z1 to

I.G.a2688.b1 .z1 ).

Table 1096: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-1 of table Z (compounds I.G.al .b4.z1 to

I.G.a2688.b4.z1 ).

Table 1097: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-1 of table Z (compounds I.G.al .b19. z1 to

I.G.a2688.b19.z1 ).

Table 1098: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-2 of table Z (compounds I.G.al .b1.z2 to

I.G.a2688.b1 .z2).

Table 1099: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-2 of table Z (compounds I.G.a1.b4.z2 to

I.G.a2688.b4.z2).

Table 1 100: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-2 of table Z (compounds I.G.al .b19. z2 to

I.G.a2688.b19.z2).

Table 1 101 : Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-3 of table Z (compounds I.G.al .b1 .z3 to

I.G.a2688.b1 .z3).

Table 1 102: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-3 of table Z (compounds I.G.a1.b4.z3 to

I.G.a2688.b4.z3).

Table 1 103: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-3 of table Z (compounds I.G.al .b19. z3 to

I.G.a2688.b19.z3).

Table 1 104: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-4 of table Z (compounds I.G.al .b1.z4 to

I.G.a2688.b1 .z4). Table 1 105: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-4 of table Z (compounds I.G.a1.b4.z4 to

I.G.a2688.b4.z4).

Table 1 106: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-4 of table Z (compounds I.G.al .b19.z4 to

I.G.a2688.b19.z4).

Table 1 107: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-5 of table Z (compounds I.G.al .b1.z5 to

I.G.a2688.b1 .z5).

Table 1 108: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-5 of table Z (compounds I.G.a1.b4.z5 to

I.G.a2688.b4.z5).

Table 1 109: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-5 of table Z (compounds I.G.al .b19. z5 to

I.G.a2688.b19.z5).

Table 1 1 10: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-6 of table Z (compounds I.G.al .b1.z6 to

I.G.a2688.b1 .z6).

Table 1 1 1 1 : Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-6 of table Z (compounds I.G.a1.b4.z6 to

I.G.a2688.b4.z6).

Table 1 1 12: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-6 of table Z (compounds I.G.al .b19.z6 to

I.G.a2688.b19.z6).

Table 1 1 13: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-7 of table Z (compounds I.G.al .b1.z7 to

I.G.a2688.b1 .z7).

Table 1 1 14: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-7 of table Z (compounds I.G.a1.b4.z7 to

I.G.a2688.b4.z7).

Table 1 1 15: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-7 of table Z (compounds I.G.al .b19.z7 to

I.G.a2688.b19.z7).

Table 1 1 16: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-8 of table Z (compounds I.G.al .b1.z8 to

I.G.a2688.b1 .z8).

Table 1 1 17: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-8 of table Z (compounds I.G.a1.b4.z8 to

I.G.a2688.b4.z8).

Table 1 1 18: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-8 of table Z (compounds I.G.al .b19. z8 to

I.G.a2688.b19.z8).

Table 1 1 19: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-9 of table Z (compounds I.G.al .b1.z9 to

I.G.a2688.b1 .z9).

Table 1 120: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-9 of table Z (compounds I.G.a1.b4.z9 to

I.G.a2688.b4.z9).

Table 1 121 : Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-9 of table Z (compounds I.G.al .b19. z9 to

I.G.a2688.b19.z9). Table 1 122: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-10 of table Z (compounds I.G.a1 .b1.z10 to I.G.a2688.b1 .z10).

Table 1 123: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-10 of table Z (compounds I.G.a1.b4.z10 to I.G.a2688.b4.z10).

Table 1 124: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-10 of table Z (compounds I.G.a1.b19.z10 to I.G.a2688.b19.z10).

Table 1 125: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-1 1 of table Z (compounds I.G.al .b1.z1 1 to I.G.a2688.b1 .z1 1 ).

Table 1 126: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-1 1 of table Z (compounds I.G.al .b4.z1 1 to I.G.a2688.b4.z1 1 ).

Table 1 127: Compounds I.G , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-1 1 of table Z (compounds I.G.a1.b19.z1 1 to I.G.a2688.b19.z1 1 ).

Table 1 128: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B (compounds I. H.a1 .b1 to I.H.a672.b1 ).

Table 1 129: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-2 in Table B (compounds I. H.a1 .b2 to I.H.a672.b2).

Table 1 130: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-3 in Table B (compounds I. H.a1 .b3 to I.H.a672.b3). Table 1 131 : Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B (compounds I. H.a1 .b4 to I.H.a672.b4).

Table 1 132: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-5 in Table B (compounds I. H.a1 .b5 to I.H.a672.b5).

Table 1 133: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-6 in Table B (compounds I. H.a1 .b6 to I.H.a672.b6).

Table 1 134: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-7 in Table B (compounds I. H.a1 .b7 to I.H.a672.b7).

Table 1 135: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-8 in Table B (compounds I. H.a1 .b8 to I.H.a672.b8).

Table 1 136: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-9 in Table B (compounds I. H.a1 .b9 to I.H.a672.b9).

Table 1 137: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-10 in Table B (compounds I. H.a1.b10 to I.H.a672.b10).

Table 1 138: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 1 in Table B (compounds I. H.a1.b1 1 to I.H.a672.b1 1 ).

Table 1 139: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-12 in Table B (compounds I. H.a1 .b12 to I.H.a672.b12).

Table 1 140: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-13 in Table B (compounds I. H.a1 .b13 to l.H.a672.b13).

Table 1 141 : Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-14 in Table B (compounds I. H.a1 .b14 to I.H.a672.b14).

Table 1 142: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-15 in Table B (compounds I. H.a1 .b15 to I.H.a672.b15).

Table 1 143: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-16 in Table B (compounds I. H.a1 .b16 to l.H.a672.b16).

Table 1 144: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-17 in Table B (compounds I. H.a1 .b17 to I.H.a672.b17).

Table 1 145: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-18 in Table B (compounds I. H.a1 .b18 to I.H.a672.b18).

Table 1 146: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B (compounds I. H.a1 .b19 to I.H.a672.b19).

Table 1 147: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-20 in Table B (compounds I. H.a1 .b20 to I.H.a672.b20).

Table 1 148: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-21 in Table B (compounds I. H.a1 .b21 to I.H.a672.b21 ).

Table 1 149: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-22 in Table B (compounds I. H.a1 .b22 to I.H.a672.b22).

Table 1 150: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-23 in Table B (compounds I. H.a1 .b23 to I.H.a672.b23).

Table 1 151 : Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-24 in Table B (compounds I. H.a1 .b24 to I.H.a672.b24). Table 1 152: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-25 in Table B (compounds I. H.a1 .b25 to I.H.a672.b25).

Table 1 153: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-26 in Table B (compounds I. H.a1 .b26 to I.H.a672.b26).

Table 1 154: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-27 in Table B (compounds I. H.a1 .b27 to I.H.a672.b27).

Table 1 155: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-28 in Table B (compounds I. H.a1 .b28 to I.H.a672.b28).

Table 1 156: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-29 in Table B (compounds I. H.a1.b29 to I.H.a672.b29).

Table 1 157: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-30 in Table B (compounds I. H.a1 .b30 to I.H.a672.b30).

Table 1 158: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-31 in Table B (compounds I. H.a1 .b31 to I.H.a672.b31 ).

Table 1 159: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-32 in Table B (compounds I. H.a1 .b32 to I.H.a672.b32).

Table 1 160: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-33 in Table B (compounds I. H.a1 .b33 to I.H.a672.b33).

Table 1 161 : Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-34 in Table B (compounds I. H.a1 .b34 to I.H.a672.b34).

Table 1 162: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-35 in Table B (compounds I. H.a1 .b35 to I.H.a672.b35).

Table 1 163: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-36 in Table B (compounds I. H.a1 .b36 to I.H.a672.b36).

Table 1 164: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-37 in Table B (compounds I. H.a1 .b37 to l.H.a672.b37).

Table 1 165: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-38 in Table B (compounds I. H.a1 .b38 to I.H.a672.b38).

Table 1 166: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-39 in Table B (compounds I. H.a1 .b39 to I.H.a672.b39).

Table 1 167: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-40 in Table B (compounds I. H.a1 .b40 to I.H.a672.b40).

Table 1 168: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-41 in Table B (compounds I. H.a1 .b41 to I.H.a672.b41 ).

Table 1 169: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-42 in Table B (compounds I. H.a1 .b42 to I.H.a672.b42).

Table 1 170: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-43 in Table B (compounds I. H.a1 .b43 to I.H.a672.b43).

Table 1 171 : Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-44 in Table B (compounds I. H.a1 .b44 to I.H.a672.b44).

Table 1 172: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-45 in Table B (compounds I. H.a1 .b45 to I.H.a672.b45). Table 1 173: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-46 in Table B (compounds I. H.a1 .b46 to I.H.a672.b46).

Table 1 174: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-47 in Table B (compounds I. H.a1.b47 to I.H.a672.b47).

Table 1 175: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-48 in Table B (compounds I. H.a1 .b48 to I.H.a672.b48).

Table 1 176: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-49 in Table B (compounds I. H.a1 .b49 to I.H.a672.b49).

Table 1 177: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-50 in Table B (compounds I. H.a1 .b50 to I.H.a672.b50).

Table 1 178: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-51 in Table B (compounds I. H.a1 .b51 to I.H.a672.b51 ).

Table 1 179: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-52 in Table B (compounds I. H.a1 .b52 to I.H.a672.b52).

Table 1 180: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-53 in Table B (compounds I. H.a1 .b53 to I.H.a672.b53).

Table 1 181 : Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-54 in Table B (compounds I. H.a1 .b54 to I.H.a672.b54).

Table 1 182: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-55 in Table B (compounds I. H.a1 .b55 to I.H.a672.b55).

Table 1 183: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-56 in Table B (compounds I. H.a1 .b56 to I.H.a672.b56).

Table 1 184: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-57 in Table B (compounds I. H.a1 .b57 to I.H.a672.b57).

Table 1 185: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-58 in Table B (compounds I. H.a1 .b58 to l.H.a672.b58).

Table 1 186: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-59 in Table B (compounds I. H.a1 .b59 to I.H.a672.b59).

Table 1 187: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-60 in Table B (compounds I. H.a1 .b60 to I.H.a672.b60).

Table 1 188: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-61 in Table B (compounds I. H.a1 .b61 to I.H.a672.b61 ).

Table 1 189: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-62 in Table B (compounds I. H.a1 .b62 to I.H.a672.b62).

Table 1 190: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-63 in Table B (compounds I. H.a1 .b63 to I.H.a672.b63).

Table 1 191 : Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-64 in Table B (compounds I. H.a1 .b64 to I.H.a672.b64).

Table 1 192: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-65 in Table B (compounds I. H.a1 .b65 to I.H.a672.b65).

Table 1 193: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-66 in Table B (compounds I. H.a1 .b66 to I.H.a672.b66). Table 1 194: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-67 in Table B (compounds I. H.a1 .b67 to I.H.a672.b67).

Table 1 195: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-68 in Table B (compounds I. H.a1 .b68 to I.H.a672.b68).

Table 1 196: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-69 in Table B (compounds I. H.a1 .b69 to I.H.a672.b69).

Table 1 197: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-70 in Table B (compounds I. H.a1 .b70 to I.H.a672.b70).

Table 1 198: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-71 in Table B (compounds I. H.a1 .b71 to I.H.a672.b71 ).

Table 1 199: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-72 in Table B (compounds I. H.a1 .b72 to I.H.a672.b72).

Table 1200: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-73 in Table B (compounds I. H.a1 .b73 to I.H.a672.b73).

Table 1201 : Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-74 in Table B (compounds I. H.a1 .b74 to I.H.a672.b74).

Table 1202: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-75 in Table B (compounds I. H.a1 .b75 to I.H.a672.b75).

Table 1203: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-76 in Table B (compounds I. H.a1 .b76 to I.H.a672.b76).

Table 1204: Compounds I.H , wherein m is 0 and wherein the combination of substituents R¹, R², X and D corresponds to one line of lines A-1 to A-672 in table A and wherein the meaning of (R⁴)_n corresponds to line B-77 in Table B (compounds I.

H. a1 .b77 to I.H.a672.b77).

Table 1205: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 of table C (compounds

I. H.a1 .b1 .c1 to I.H.a2688.b1 .c1 ).

Table 1206: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 of table C (compounds

I.H.a1.b4.c1 to I.H.a2688.b4.c1 ).

Table 1207: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 of table C (compounds

I.H.a1.b19.c1 to I.H.a2688.b19.c1 ).

Table 1208: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-2 of table C (compounds

I.H.a1.b1.c2 to I.H.a2688.b1 .c2).

Table 1209: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-2 of table C (compounds

I.H.a1.b4.c2 to I.H.a2688.b4.c2).

Table 1210: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-2 of table C (compounds

I.H.a1.b19.c2 to I.H.a2688.b19.c2).

Table 121 1 : Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-3 of table C (compounds

I.H.al .b1.c3 to I.H.a2688.b1 .c3).

Table 1212: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-3 of table C (compounds

I.H.a1 .b4.c3 to I.H.a2688.b4.c3). Table 1213: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-3 of table C (compounds I.H.a1.b19.c3 to I.H.a2688.b19.c3).

Table 1214: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-4 of table C (compounds I.H.a1.b1.c4 to I.H.a2688.b1 .c4).

Table 1215: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-4 of table C (compounds I.H.a1.b4.c4 to I.H.a2688.b4.c4).

Table 1216: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-4 of table C (compounds I.H.a1.b19.c4 to I.H.a2688.b19.c4).

Table 1217: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-5 of table C (compounds I.H.al .b1.c5 to I.H.a2688.b1 .c5).

Table 1218: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-5 of table C (compounds I.H.a1.b4.c5 to I.H.a2688.b4.c5).

Table 1219: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-5 of table C (compounds I.H.a1.b19.c5 to I.H.a2688.b19.c5).

Table 1220: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-6 of table C (compounds I.H.al .b1.c6 to I.H.a2688.b1 .c6).

Table 1221 : Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-6 of table C (compounds I.H.a1.b4.c6 to I.H.a2688.b4.c6).

Table 1222: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-6 of table C (compounds I.H.a1.b19.c6 to I.H.a2688.b19.c6).

Table 1223: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-7 of table C (compounds I.H.a1.b1.c7 to I.H.a2688.b1 .c7).

Table 1224: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-7 of table C (compounds I.H.a1.b4.c7 to I.H.a2688.b4.c7).

Table 1225: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-7 of table C (compounds I.H.a1.b19.c7 to I.H.a2688.b19.c7).

Table 1226: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-8 of table C (compounds I.H.al .b1.c8 to I.H.a2688.b1 .c8).

Table 1227: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-8 of table C (compounds I.H.a1.b4.c8 to I.H.a2688.b4.c8).

Table 1228: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-8 of table C (compounds I.H.a1.b19.c8 to I.H.a2688.b19.c8).

Table 1229: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-9 of table C (compounds I.H.al .b1.c9 to I.H.a2688.b1 .c9). Table 1230: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-9 of table C (compounds I.H.a1.b4.c9 to I.H.a2688.b4.c9).

Table 1231 : Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-9 of table C (compounds I.H.a1.b19.c9 to I.H.a2688.b19.c9).

Table 1232: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-10 of table C (compounds I.H.a1.b1.c10 to I.H.a2688.b1.c10).

Table 1233: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-10 of table C (compounds I.H.a1 .b4.c10 to I.H.a2688.b4.c10).

Table 1234: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-10 of table C (compounds I.H.a1.b19.c10 to I.H.a2688.b19.c10).

Table 1235: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 1 of table C (compounds I.H.a1.b1.c1 1 to I.H.a2688.b1.c1 1 ).

Table 1236: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 1 of table C (compounds I.H.a1.b4.c1 1 to I.H.a2688.b4.c1 1 ).

Table 1237: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-1 1 of table C (compounds I.H.a1.b19.c1 1 to I.H.a2688.b19.c1 1 ).

Table 1238: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-12 of table C (compounds I.H.a1.b1.c12 to I.H.a2688.b1.c12).

Table 1239: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-12 of table C (compounds I.H.a1.b4.c12 to I.H.a2688.b4.c12).

Table 1240: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-12 of table C (compounds I.H.a1 .b19.c12 to I.H.a2688.b19.c12).

Table 1241 : Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-13 of table C (compounds I.H.a1.b1.c13 to I.H.a2688.b1.c13).

Table 1242: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-13 of table C (compounds I.H.a1.b4.c13 to I.H.a2688.b4.c13).

Table 1243: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-13 of table C (compounds I.H.a1.b19.c13 to I.H.a2688.b19.c13).

Table 1244: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-14 of table C (compounds I.H.a1.b1.c14 to I.H.a2688.b1.c14).

Table 1245: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-14 of table C (compounds I.H.a1.b4.c14 to I.H.a2688.b4.c14).

Table 1246: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-14 of table C (compounds I.H.a1.b19.c14 to I.H.a2688.b19.c14). Table 1247: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-15 of table C (compounds I.H.a1.b1.c15 to I.H.a2688.b1.c15).

Table 1248: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-15 of table C (compounds I.H.a1.b4.c15 to I.H.a2688.b4.c15).

Table 1249: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-15 of table C (compounds I.H.a1 .b19.c15 to I.H.a2688.b19.c15).

Table 1250: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-16 of table C (compounds I.H.a1.b1.c16 to I.H.a2688.b1.c16).

Table 1251 : Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-16 of table C (compounds I.H.a1.b4.c16 to I.H.a2688.b4.c16).

Table 1252: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-16 of table C (compounds I.H.a1.b19.c16 to I.H.a2688.b19.c16).

Table 1253: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is phenyl and R^L is as defined in line C-17 of table C (compounds I.H.a1.b1.c17 to I.H.a2688.b1.c17).

Table 1254: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is phenyl and R^L is as defined in line C-17 of table C (compounds I.H.a1.b4.c17 to I.H.a2688.b4.c17).

Table 1255: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is phenyl and R^L is as defined in line C-17 of table C (compounds I.H.a1.b19.c17 to I.H.a2688.b19.c17).

Table 1256: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-1 of table Z (compounds I.H.al .b1 .z1 to

I.H.a2688.b1.z1 ).

Table 1257: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-1 of table Z (compounds I.H.al .b4.z1 to

I.H.a2688.b4.z1 ).

Table 1258: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-1 of table Z (compounds I.H.al .b19.z1 to

I.H.a2688.b19.z1 ).

Table 1259: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-2 of table Z (compounds I.H.al .b1 .z2 to

I.H.a2688.b1.z2).

Table 1260: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-2 of table Z (compounds I.H.a1.b4.z2 to

I.H.a2688.b4.z2).

Table 1261 : Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-2 of table Z (compounds I.H.al .b19.z2 to

I.H.a2688.b19.z2).

Table 1262: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-3 of table Z (compounds I.H.al .b1.z3 to

I.H.a2688.b1.z3).

Table 1263: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-3 of table Z (compounds I.H.a1.b4.z3 to

I.H.a2688.b4.z3). Table 1264: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-3 of table Z (compounds I.H.al .b19.z3 to

I.H.a2688.b19.z3).

Table 1265: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-4 of table Z (compounds I.H.al .b1 .z4 to

I.H.a2688.b1.z4).

Table 1266: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-4 of table Z (compounds I.H.a1.b4.z4 to

I.H.a2688.b4.z4).

Table 1267: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-4 of table Z (compounds I.H.al .b19.z4 to

I.H.a2688.b19.z4).

Table 1268: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-5 of table Z (compounds I.H.al .b1 .z5 to

I.H.a2688.b1.z5).

Table 1269: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-5 of table Z (compounds I.H.a1.b4.z5 to

I.H.a2688.b4.z5).

Table 1270: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-5 of table Z (compounds I.H.al .b19.z5 to

I.H.a2688.b19.z5).

Table 1271 : Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-6 of table Z (compounds I.H.al .b1 .z6 to

I.H.a2688.b1.z6).

Table 1272: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-6 of table Z (compounds I.H.a1.b4.z6 to

I.H.a2688.b4.z6).

Table 1273: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-6 of table Z (compounds I.H.al .b19.z6 to

I.H.a2688.b19.z6).

Table 1274: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-7 of table Z (compounds I.H.al .b1 .z7 to

I.H.a2688.b1.z7).

Table 1275: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-7 of table Z (compounds I.H.a1.b4.z7 to

I.H.a2688.b4.z7).

Table 1276: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-7 of table Z (compounds I.H.al .b19.z7 to

I.H.a2688.b19.z7).

Table 1277: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-8 of table Z (compounds I.H.al .b1 .z8 to

I.H.a2688.b1.z8).

Table 1278: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-8 of table Z (compounds I.H.a1.b4.z8 to

I.H.a2688.b4.z8).

Table 1279: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-8 of table Z (compounds I.H.al .b19.z8 to

I.H.a2688.b19.z8).

Table 1280: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-9 of table Z (compounds I.H.al .b1 .z9 to

I.H.a2688.b1.z9). Table 1281 : Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-9 of table Z (compounds I.H.a1.b4.z9 to

I.H.a2688.b4.z9).

Table 1282: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-9 of table Z (compounds I.H.al .b19.z9 to

I.H.a2688.b19.z9).

Table 1283: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-10 of table Z (compounds I.H.al .b1.z10 to I.H.a2688.b1 .z10).

Table 1284: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-10 of table Z (compounds I.H.al .b4.z10 to I.H.a2688.b4.z10).

Table 1285: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-10 of table Z (compounds I.H.a1.b19.z10 to I.H.a2688.b19.z10).

Table 1286: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-1 in Table B and wherein Z is as defined in line Z-1 1 of table Z (compounds I.H.al .b1.z1 1 to I.H.a2688.b1 .z1 1 ).

Table 1287: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-4 in Table B and wherein Z is as defined in line Z-1 1 of table Z (compounds I.H.al .b4.z1 1 to I.H.a2688.b4.z1 1 ).

Table 1288: Compounds I.H , wherein m is 1 and wherein the combination of substituents R¹, R², X, D, Y and the position of Y corresponds to one line of lines A-1 to A-2688 in table A and wherein the meaning of (R⁴)_n corresponds to line B-19 in Table B and wherein Z is as defined in line Z-1 1 of table Z (compounds I.H.a1.b19.z1 1 to I.H.a2688.b19.z1 1 ).

Accordingly a compound I having the following formula

wherein A is N, D is hydrogen, R¹ is ethyl, R² is hydrogen, X is OH, (R⁴)_n is 4-CI, m is 0, R⁵ is methyl and wherein R⁶ and R⁷ are hydrogen, is denominated as compound I.B.a98.b6 and is individualized in Table 167.

The compounds I and the compositions according to the invention, respectively, are suitable as fungicides. They are distinguished by an outstanding effectiveness against a broad spectrum of phytopathogenic fungi, including soil-borne fungi, which derive especially from the classes of the Plasmodiophoromycetes, Peronosporomycetes (syn. Oomycetes), Chytridiomycetes, Zygomycetes, Ascomycetes, Basidiomycetes and

Deuteromycetes (syn. Fungi imperfecti). Some are systemically effective and they can be used in crop protection as foliar fungicides, fungicides for seed dressing and soil fungicides. Moreover, they are suitable for controlling harmful fungi, which inter alia occur in wood or roots of plants.

The compounds I and the compositions according to the invention are particularly important in the control of a multitude of phytopathogenic fungi on various cultivated plants, such as cereals, e. g. wheat, rye, barley, triticale, oats or rice; beet, e. g. sugar beet or fodder beet; fruits, such as pomes, stone fruits or soft fruits, e. g. apples, pears, plums, peaches, almonds, cherries, strawberries, raspberries, blackberries or gooseberries; leguminous plants, such as lentils, peas, alfalfa or soybeans; oil plants, such as rape, mustard, olives, sunflowers, coconut, cocoa beans, castor oil plants, oil palms, ground nuts or soybeans; cucurbits, such as squashes, cucumber or melons; fiber plants, such as cotton, flax, hemp or jute; citrus fruit, such as oranges, lemons, grapefruits or mandarins; vegetables, such as spinach, lettuce, asparagus, cabbages, carrots, onions, tomatoes, potatoes, cucurbits or paprika; lauraceous plants, such as avocados, cinnamon or camphor; energy and raw material plants, such as corn, soybean, rape, sugar cane or oil palm; corn; tobacco; nuts; coffee; tea; bananas; vines (table grapes and grape juice grape vines); hop; turf; sweet leaf (also called Stevia); natural rubber plants or ornamental and forestry plants, such as flowers, shrubs, broad- leaved trees or evergreens, e. g. conifers; and on the plant propagation material, such as seeds, and the crop material of these plants.

Preferably, compounds I and compositions thereof, respectively are used for controlling a multitude of fungi on field crops, such as potatoes sugar beets, tobacco, wheat, rye, barley, oats, rice, corn, cotton, soybeans, rape, legumes, sunflowers, coffee or sugar cane; fruits; vines; ornamentals; or vegetables, such as cucumbers, tomatoes, beans or squashes. The term "plant propagation material" is to be understood to denote all the generative parts of the plant such as seeds and vegetative plant material such as cuttings and tubers (e. g. potatoes), which can be used for the multiplication of the plant. This includes seeds, roots, fruits, tubers, bulbs, rhizomes, shoots, sprouts and other parts of plants, including seedlings and young plants, which are to be transplanted after germination or after emergence from soil. These young plants may also be protected before transplantation by a total or partial treatment by immersion or pouring.

Preferably, treatment of plant propagation materials with compounds I and compositions thereof, respectively, is used for controlling a multitude of fungi on cereals, such as wheat, rye, barley and oats; rice, corn, cotton and soybeans.

The term "cultivated plants" is to be understood as including plants which have been modified by breeding, mutagenesis or genetic engineering including but not limiting to agricultural biotech products on the market or in development (cf. http://cera-gmc.org/, see GM crop database therein). Genetically modified plants are plants, which genetic material has been so modified by the use of recombinant DNA techniques that under natural circumstances cannot readily be obtained by cross breeding, mutations or natural recombination. Typically, one or more genes have been integrated into the genetic material of a genetically modified plant in order to improve certain properties of the plant. Such genetic modifications also include but are not limited to targeted post- translational modification of protein(s), oligo- or polypeptides e. g. by glycosylation or polymer additions such as prenylated, acetylated or farnesylated moieties or PEG moieties. Plants that have been modified by breeding, mutagenesis or genetic engineering, e. g. have been rendered tolerant to applications of specific classes of herbicides, such as auxin herbicides such as dicamba or 2,4-D; bleacher herbicides such as hydroxyl- phenylpyruvate dioxygenase (HPPD) inhibitors or phytoene desaturase (PDS) inhibitors; acetolactate synthase (ALS) inhibitors such as sulfonyl ureas or imidazolinones; enolpyruvylshikimate-3-phosphate synthase (EPSPS) inhibitors, such as glyphosate; glutamine synthetase (GS) inhibitors such as glufosinate; protoporphyrinogen-IX oxidase inhibitors; lipid biosynthesis inhibitors such as acetyl CoA carboxylase (ACCase) inhibitors; or oxynil (i. e. bromoxynil or ioxynil) herbicides as a result of conventional methods of breeding or genetic engineering. Furthermore, plants have been made resistant to multiple classes of herbicides through multiple genetic modifications, such as resistance to both glyphosate and glufosinate or to both glyphosate and a herbicide from another class such as ALS inhibitors, HPPD inhibitors, auxin herbicides, or ACCase inhibitors. These herbicide resistance technologies are e. g. described in Pest Managem. Sci. 61 , 2005, 246; 61 , 2005, 258; 61 , 2005, 277; 61 , 2005, 269; 61 , 2005, 286; 64, 2008, 326; 64, 2008, 332; Weed Sci. 57, 2009, 108; Austral. J. Agricult. Res. 58, 2007, 708; Science 316, 2007, 1 185; and references quoted therein. Several cultivated plants have been rendered tolerant to herbicides by conventional methods of breeding (mutagenesis), e. g. Clearfield® summer rape (Canola, BASF SE, Germany) being tolerant to imidazolinones, e. g. imazamox, or ExpressSun® sunflowers (DuPont, USA) being tolerant to sulfonyl ureas, e. g. tribenuron. Genetic engineering methods have been used to render cultivated plants such as soybean, cotton, corn, beets and rape, tolerant to herbicides such as glyphosate and glufosinate, some of which are commercially available under the trade names RoundupReady® (glyphosate-tolerant, Monsanto, U.S.A.), Cultivance® (imidazolinone tolerant, BASF SE, Germany) and LibertyLink® (glufosinate-tolerant, Bayer CropScience, Germany).

Furthermore, plants are also covered that are by the use of recombinant DNA techniques capable to synthesize one or more insecticidal proteins, especially those known from the bacterial genus Bacillus, particularly from Bacillus thuringiensis, such as δ-endotoxins, e. g. CrylA(b), CrylA(c), CrylF, CrylF(a2), CryllA(b), CrylllA,

CrylllB(bl ) or Cry9c; vegetative insecticidal proteins (VIP), e. g. VIP1 , VIP2, VIP3 or VIP3A; insecticidal proteins of bacteria colonizing nematodes, e. g. Photorhabdus spp. or Xenorhabdus spp.; toxins produced by animals, such as scorpion toxins, arachnid toxins, wasp toxins, or other insect-specific neurotoxins; toxins produced by fungi, such Streptomycetes toxins, plant lectins, such as pea or barley lectins; agglutinins;

proteinase inhibitors, such as trypsin inhibitors, serine protease inhibitors, patatin, cystatin or papain inhibitors; ribosome-inactivating proteins (RIP), such as ricin, maize- RIP, abrin, luffin, saporin or bryodin; steroid metabolism enzymes, such as 3-hydroxy- steroid oxidase, ecdysteroid-IDP-glycosyl-transferase, cholesterol oxidases, ecdysone inhibitors or HMG-CoA-reductase; ion channel blockers, such as blockers of sodium or calcium channels; juvenile hormone esterase; diuretic hormone receptors (helicokinin receptors); stilben synthase, bibenzyl synthase, chitinases or glucanases. In the context of the present invention these insecticidal proteins or toxins are to be understood expressly also as pre-toxins, hybrid proteins, truncated or otherwise modified proteins. Hybrid proteins are characterized by a new combination of protein domains, (see, e. g. WO 02/015701 ). Further examples of such toxins or genetically modified plants capable of synthesizing such toxins are disclosed, e. g., in EP-A 374 753, WO 93/007278, WO 95/34656, EP-A 427 529, EP-A 451 878, WO 03/18810 und WO 03/52073. The methods for producing such genetically modified plants are generally known to the person skilled in the art and are described, e. g. in the publications mentioned above. These insecticidal proteins contained in the genetically modified plants impart to the plants producing these proteins tolerance to harmful pests from all taxonomic groups of athropods, especially to beetles (Coeloptera), two-winged insects (Diptera), and moths (Lepidoptera) and to nematodes (Nematoda). Genetically modified plants capable to synthesize one or more insecticidal proteins are, e. g., described in the publications mentioned above, and some of which are commercially available such as YieldGard® (corn cultivars producing the CrylAb toxin), YieldGard® Plus (corn cultivars producing CrylAb and Cry3Bb1 toxins), Starlink® (corn cultivars producing the Cry9c toxin), Herculex® RW (corn cultivars producing Cry34Ab1 , Cry35Ab1 and the enzyme Phosphinothricin-N-Acetyltransferase [PAT]); NuCOTN® 33B (cotton cultivars producing the CrylAc toxin), Bollgard® I (cotton cultivars producing the CrylAc toxin), Bollgard® II (cotton cultivars producing CrylAc and Cry2Ab2 toxins); VIPCOT® (cotton cultivars producing a VIP-toxin); NewLeaf® (potato cultivars producing the Cry3A toxin); Bt-Xtra®, NatureGard®, KnockOut®, BiteGard®, Protecta®, Bt1 1 (e. g. Agrisure® CB) and Bt176 from Syngenta Seeds SAS, France, (corn cultivars producing the CrylAb toxin and PAT enyzme), MIR604 from Syngenta Seeds SAS, France (corn cultivars producing a modified version of the Cry3A toxin, c.f. WO 03/018810), MON 863 from Monsanto Europe S.A., Belgium (corn cultivars producing the Cry3Bb1 toxin), IPC 531 from Monsanto Europe S.A., Belgium (cotton cultivars producing a modified version of the CrylAc toxin) and 1507 from Pioneer Overseas Corporation, Belgium (corn cultivars producing the Cry1 F toxin and PAT enzyme). Furthermore, plants are also covered that are by the use of recombinant DNA techniques capable to synthesize one or more proteins to increase the resistance or tolerance of those plants to bacterial, viral or fungal pathogens. Examples of such proteins are the so-called "pathogenesis-related proteins" (PR proteins, see, e. g. EP-A 392 225), plant disease resistance genes (e. g. potato cultivars, which express resistance genes acting against Phytophthora infestans derived from the mexican wild potato Solanum bulbocastanum) or T4-lysozym (e. g. potato cultivars capable of synthesizing these proteins with increased resistance against bacteria such as Erwinia amylvora). The methods for producing such genetically modified plants are generally known to the person skilled in the art and are described, e. g. in the publications mentioned above.

Furthermore, plants are also covered that are by the use of recombinant DNA techniques capable to synthesize one or more proteins to increase the productivity (e. g. bio mass production, grain yield, starch content, oil content or protein content), tolerance to drought, salinity or other growth-limiting environmental factors or tolerance to pests and fungal, bacterial or viral pathogens of those plants.

Furthermore, plants are also covered that contain by the use of recombinant DNA techniques a modified amount of substances of content or new substances of content, specifically to improve human or animal nutrition, e. g. oil crops that produce health- promoting long-chain omega-3 fatty acids or unsaturated omega-9 fatty acids (e. g. Nexera® rape, DOW Agro Sciences, Canada).

Furthermore, plants are also covered that contain by the use of recombinant DNA techniques a modified amount of substances of content or new substances of content, specifically to improve raw material production, e. g. potatoes that produce increased amounts of amylopectin (e. g. Amflora® potato, BASF SE, Germany).

The compounds I and compositions thereof, respectively, are particularly suitable for controlling the following plant diseases:

Albugo spp. (white rust) on ornamentals, vegetables (e. g. A. Candida) and sunflowers (e. g. A. tragopogonis); Alternaria spp. (Alternaria leaf spot) on vegetables, rape (A. brassicola or brassicae), sugar beets (A. tenuis), fruits, rice, soybeans, potatoes (e. g. A. solani or A. alternata), tomatoes (e. g. A. solani or A. alternata) and wheat; Aphano- myces spp. on sugar beets and vegetables; Ascochyta spp. on cereals and vegetables, e. g. A. tritici (anthracnose) on wheat and A. hordei on barley; Bipolaris and Drechslera spp. (teleomorph: Cochliobolus spp.), e. g. Southern leaf blight (D. maydis) or Northern leaf blight (B. zeicola) on corn, e. g. spot blotch (B. sorokiniana) on cereals and e.g. B. oryzae on rice and turfs; Blumeria (formerly Erysiphe) graminis (powdery mildew) on cereals (e. g. on wheat or barley); Botrytis cinerea (teleomorph: Botryotinia fuckeliana: grey mold) on fruits and berries (e. g. strawberries), vegetables (e. g. lettuce, carrots, celery and cabbages), rape, flowers, vines, forestry plants and wheat; Bremia lactucae (downy mildew) on lettuce; Ceratocystis (syn. Ophiostoma) spp. (rot or wilt) on broad- leaved trees and evergreens, e. g. C. ulmi (Dutch elm disease) on elms; Cercospora spp. (Cercospora leaf spots) on corn (e.g. Gray leaf spot: C. zeae-maydis), rice, sugar beets (e. g. C. beticola), sugar cane, vegetables, coffee, soybeans (e. g. C. sojina or C. kikuchii) and rice; Cladosporium spp. on tomatoes (e. g. C. fulvum: leaf mold) and cereals, e. g. C. herbarum (black ear) on wheat; Claviceps purpurea (ergot) on cereals; Cochliobolus (anamorph: Helminthosporium of Bipolaris) spp. (leaf spots) on corn (C. carbonum), cereals (e. g. C. sativus, anamorph: B. sorokiniana) and rice (e. g. C.

miyabeanus, anamorph: H. oryzae); Colletotrichum (teleomorph: Glomerella) spp. (anthracnose) on cotton (e. g. C. gossypii), corn (e. g. C. graminicola: Anthracnose stalk rot), soft fruits, potatoes (e. g. C. coccodes: black dot), beans (e. g. C. lindemuthi- anum) and soybeans (e. g. C. truncatum or C. gloeosporioides); Corticium spp., e. g. C. sasakii (sheath blight) on rice; Corynespora cassiicola (leaf spots) on soybeans and ornamentals; Cycloconium spp., e. g. C. oleaginum on olive trees; Cylindrocarpon spp. (e. g. fruit tree canker or young vine decline, teleomorph: Nectria or Neonectria spp.) on fruit trees, vines (e. g. C. liriodendri, teleomorph: Neonectria liriodendri: Black Foot Disease) and ornamentals; Dematophora (teleomorph: Rosellinia) necatrix (root and stem rot) on soybeans; Diaporthe spp., e. g. D. phaseolorum (damping off) on soybeans; Drechslera (syn. Helminthosporium, teleomorph: Pyrenophora) spp. on corn, cereals, such as barley (e. g. D. teres, net blotch) and wheat (e. g. D. tritici-repentis: tan spot), rice and turf; Esca (dieback, apoplexy) on vines, caused by Formitiporia (syn. Phellinus) punctata, F. mediterranea, Phaeomoniella chlamydospora (earlier Phaeo- acremonium chlamydosporum), Phaeoacremonium aleophilum and/or Botryosphaeria obtusa; Elsinoe spp. on pome fruits (E. pyri), soft fruits (E. veneta: anthracnose) and vines (E. ampelina: anthracnose); Entyloma oryzae (leaf smut) on rice; Epicoccum spp. (black mold) on wheat; Erysiphe spp. (powdery mildew) on sugar beets (E. betae), vegetables (e. g. E. pisi), such as cucurbits (e. g. E. cichoracearum), cabbages, rape (e. g. E. cruciferarum); Eutypa lata (Eutypa canker or dieback, anamorph: Cytosporina lata, syn. Libertella blepharis) on fruit trees, vines and ornamental woods; Exserohilum (syn. Helminthosporium) spp. on corn (e. g. E. turcicum); Fusarium (teleomorph:

Gibberella) spp. (wilt, root or stem rot) on various plants, such as F. graminearum or F. culmorum (root rot, scab or head blight) on cereals (e. g. wheat or barley), F. oxy- sporum on tomatoes, F. solani on soybeans and F. verticillioides on corn; Gaeumanno- myces graminis (take-all) on cereals (e. g. wheat or barley) and corn; Gibberella spp. on cereals (e. g. G. zeae) and rice (e. g. G. fujikuroi: Bakanae disease); Glomerella cingulata on vines, pome fruits and other plants and G. gossypii on cotton; Grain- staining complex on rice; Guignardia bidwellii (black rot) on vines; Gymnosporangium spp. on rosaceous plants and junipers, e. g. G. sabinae (rust) on pears; Helmintho- sporium spp. (syn. Drechslera, teleomorph: Cochliobolus) on corn, cereals and rice; Hemileia spp., e. g. H. vastatrix (coffee leaf rust) on coffee; Isariopsis clavispora (syn. Cladosporium vitis) on vines; Macrophomina phaseolina (syn. phaseoli) (root and stem rot) on soybeans and cotton; Microdochium (syn. Fusarium) nivale (pink snow mold) on cereals (e. g. wheat or barley); Microsphaera diffusa (powdery mildew) on soybeans; Monilinia spp., e. g. M. laxa, M. fructicola and M. fructigena (bloom and twig blight, brown rot) on stone fruits and other rosaceous plants; Mycosphaerella spp. on cereals, bananas, soft fruits and ground nuts, such as e. g. M. graminicola (anamorph: Septoria tritici, Septoria blotch) on wheat or M. fijiensis (black Sigatoka disease) on bananas; Peronospora spp. (downy mildew) on cabbage (e. g. P. brassicae), rape (e. g. P.

parasitica), onions (e. g. P. destructor), tobacco (P. tabacina) and soybeans (e. g. P. manshurica); Phakopsora pachyrhizi and P. meibomiae (soybean rust) on soybeans; Phialophora spp. e. g. on vines (e. g. P. tracheiphila and P. tetraspora) and soybeans (e. g. P. gregata: stem rot); Phoma lingam (root and stem rot) on rape and cabbage and P. betae (root rot, leaf spot and damping-off) on sugar beets; Phomopsis spp. on sunflowers, vines (e. g. P. viticola: can and leaf spot) and soybeans (e. g. stem rot: P. phaseoli, teleomorph: Diaporthe phaseolorum); Physoderma maydis (brown spots) on corn; Phytophthora spp. (wilt, root, leaf, fruit and stem root) on various plants, such as paprika and cucurbits (e. g. P. capsici), soybeans (e. g. P. megasperma, syn. P. sojae), potatoes and tomatoes (e. g. P. infestans: late blight) and broad-leaved trees (e. g. P. ramorum: sudden oak death); Plasmodiophora brassicae (club root) on cabbage, rape, radish and other plants; Plasmopara spp., e. g. P. viticola (grapevine downy mildew) on vines and P. halstedii on sunflowers; Podosphaera spp. (powdery mildew) on rosaceous plants, hop, pome and soft fruits, e. g. P. leucotricha on apples; Polymyxa spp., e. g. on cereals, such as barley and wheat (P. graminis) and sugar beets (P. betae) and thereby transmitted viral diseases; Pseudocercosporella herpotrichoides (eyespot, teleomorph: Tapesia yallundae) on cereals, e. g. wheat or barley; Pseudoperonospora (downy mildew) on various plants, e. g. P. cubensis on cucurbits or P. humili on hop; Pseudopezicula tracheiphila (red fire disease or .rotbrenner', anamorph: Phialophora) on vines; Puccinia spp. (rusts) on various plants, e. g. P. triticina (brown or leaf rust), P. striiformis (stripe or yellow rust), P. hordei (dwarf rust), P. graminis (stem or black rust) or P. recondita (brown or leaf rust) on cereals, such as e. g. wheat, barley or rye, P. kuehnii (orange rust) on sugar cane and P. asparagi on asparagus; Pyrenophora (anamorph: Drechslera) tritici-repentis (tan spot) on wheat or P. teres (net blotch) on barley; Pyricularia spp., e. g. P. oryzae (teleomorph: Magnaporthe grisea, rice blast) on rice and P. grisea on turf and cereals; Pythium spp. (damping-off) on turf, rice, corn, wheat, cotton, rape, sunflowers, soybeans, sugar beets, vegetables and various other plants (e. g. P. ultimum or P. aphanidermatum); Ramularia spp., e. g. R. collo-cygni (Ramularia leaf spots, Physiological leaf spots) on barley and R. beticola on sugar beets; Rhizoctonia spp. on cotton, rice, potatoes, turf, corn, rape, potatoes, sugar beets, vegetables and various other plants, e. g. R. solani (root and stem rot) on soybeans, R. solani (sheath blight) on rice or R. cerealis (Rhizoctonia spring blight) on wheat or barley; Rhizopus stolonifer (black mold, soft rot) on strawberries, carrots, cabbage, vines and tomatoes; Rhynchosporium secalis (scald) on barley, rye and triticale; Sarocladium oryzae and S. attenuatum (sheath rot) on rice; Sclerotinia spp. (stem rot or white mold) on vegetables and field crops, such as rape, sunflowers (e. g. S. sclerotiorum) and soybeans (e. g. S. rolfsii or S. sclerotiorum); Septoria spp. on various plants, e. g. S. glycines (brown spot) on soybeans, S. tritici (Septoria blotch) on wheat and S. (syn. Stagonospora) nodorum (Stagonospora blotch) on cereals;

Uncinula (syn. Erysiphe) necator (powdery mildew, anamorph: Oidium tuckeri) on vines; Setospaeria spp. (leaf blight) on corn (e. g. S. turcicum, syn. Helminthosporium turcicum) and turf; Sphacelotheca spp. (smut) on corn, (e. g. S. reiliana: head smut), sorghum und sugar cane; Sphaerotheca fuliginea (powdery mildew) on cucurbits;

Spongospora subterranea (powdery scab) on potatoes and thereby transmitted viral diseases; Stagonospora spp. on cereals, e. g. S. nodorum (Stagonospora blotch, teleomorph: Leptosphaeria [syn. Phaeosphaeria] nodorum) on wheat; Synchytrium endobioticum on potatoes (potato wart disease); Taphrina spp., e. g. T. deformans (leaf curl disease) on peaches and T. pruni (plum pocket) on plums; Thielaviopsis spp.

(black root rot) on tobacco, pome fruits, vegetables, soybeans and cotton, e. g. T.

basicola (syn. Chalara elegans); Tilletia spp. (common bunt or stinking smut) on cereals, such as e. g. T. tritici (syn. T. caries, wheat bunt) and T. controversa (dwarf bunt) on wheat; Typhula incarnata (grey snow mold) on barley or wheat; Urocystis spp., e. g. U. occulta (stem smut) on rye; Uromyces spp. (rust) on vegetables, such as beans (e. g. U. appendiculatus, syn. U. phaseoli) and sugar beets (e. g. U. betae); Ustilago spp. (loose smut) on cereals (e. g. U. nuda and U. avaenae), corn (e. g. U. maydis: corn smut) and sugar cane; Venturia spp. (scab) on apples (e. g. V. inaequalis) and pears; and Verticillium spp. (wilt) on various plants, such as fruits and ornamentals, vines, soft fruits, vegetables and field crops, e. g. V. dahliae on strawberries, rape, potatoes and tomatoes.

The compounds I and compositions thereof, respectively, are also suitable for controlling harmful fungi in the protection of stored products or harvest and in the protection of materials. The term "protection of materials" is to be understood to denote the protection of technical and non-living materials, such as adhesives, glues, wood, paper and paperboard, textiles, leather, paint dispersions, plastics, colling lubricants, fiber or fabrics, against the infestation and destruction by harmful microorganisms, such as fungi and bacteria. As to the protection of wood and other materials, the particular attention is paid to the following harmful fungi: Ascomycetes such as

Ophiostoma spp., Ceratocystis spp., Aureobasidium pullulans, Sclerophoma spp.,

Chaetomium spp., Humicola spp., Petriella spp., Trichurus spp.; Basidiomycetes such as Coniophora spp., Coriolus spp., Gloeophyllum spp., Lentinus spp., Pleurotus spp., Poria spp., Serpula spp. and Tyromyces spp., Deuteromycetes such as Aspergillus spp., Cladosporium spp., Penicillium spp., Trichorma spp., Alternaria spp.,

Paecilomyces spp. and Zygomycetes such as Mucor spp., and in addition in the protection of stored products and harvest the following yeast fungi are worthy of note: Candida spp. and Saccharomyces cerevisae.

The method of treatment according to the invention can also be used in the field of protecting stored products or harvest against attack of fungi and microorganisms.

According to the present invention, the term "stored products" is understood to denote natural substances of plant or animal origin and their processed forms, which have been taken from the natural life cycle and for which long-term protection is desired.

Stored products of crop plant origin, such as plants or parts thereof, for example stalks, leafs, tubers, seeds, fruits or grains, can be protected in the freshly harvested state or in processed form, such as pre-dried, moistened, comminuted, ground, pressed or roasted, which process is also known as post-harvest treatment. Also falling under the definition of stored products is timber, whether in the form of crude timber, such as construction timber, electricity pylons and barriers, or in the form of finished articles, such as furniture or objects made from wood. Stored products of animal origin are hides, leather, furs, hairs and the like. The combinations according the present invention can prevent disadvantageous effects such as decay, discoloration or mold. Preferably "stored products" is understood to denote natural substances of plant origin and their processed forms, more preferably fruits and their processed forms, such as pomes, stone fruits, soft fruits and citrus fruits and their processed forms.

The compounds I and compositions thereof, resepectively, may be used for improving the health of a plant. The invention also relates to a method for improving plant health by treating a plant, its propagation material and/or the locus where the plant is growing or is to grow with an effective amount of compounds I and compositions thereof, respectively. The term "plant health" is to be understood to denote a condition of the plant and/or its products which is determined by several indicators alone or in combination with each other such as yield (e. g. increased biomass and/or increased content of valuable ingredients), plant vigor (e. g. improved plant growth and/or greener leaves ("greening effect")), quality (e. g. improved content or composition of certain ingredients) and tolerance to abiotic and/or biotic stress. The above identified indicators for the health condition of a plant may be interdependent or may result from each other.

The compounds of formula I can be present in different crystal modifications whose biological activity may differ. They are likewise subject matter of the present invention.

The compounds I are employed as such or in form of compositions by treating the fungi or the plants, plant propagation materials, such as seeds, soil, surfaces, materials or rooms to be protected from fungal attack with a fungicidally effective amount of the active substances. The application can be carried out both before and after the infection of the plants, plant propagation materials, such as seeds, soil, surfaces, materials or rooms by the fungi. Plant propagation materials may be treated with compounds I as such or a composition comprising at least one compound I prophylactically either at or before planting or transplanting.

The invention also relates to agrochemical compositions comprising an auxiliary and at least one compound I according to the invention. In a particular embodiment, the invention relates to compositions, further comprising seed.

An agrochemical composition comprises a fungicidally effective amount of a compound I. The term "effective amount" denotes an amount of the composition or of the compounds I, which is sufficient for controlling harmful fungi on cultivated plants or in the protection of materials and which does not result in a substantial damage to the treated plants. Such an amount can vary in a broad range and is dependent on various factors, such as the fungal species to be controlled, the treated cultivated plant or material, the climatic conditions and the specific compound I used.

The compounds I, their N-oxides and salts can be converted into customary types of agrochemical compositions, e. g. solutions, emulsions, suspensions, dusts, powders, pastes, granules, pressings, capsules, and mixtures thereof. Examples for composition types are suspensions (e.g. SC, OD, FS), emulsifiable concentrates (e.g. EC), emul- sions (e.g. EW, EO, ES, ME), capsules (e.g. CS, ZC), pastes, pastilles, wettable powders or dusts (e.g. WP, SP, WS, DP, DS), pressings (e.g. BR, TB, DT), granules (e.g. WG, SG, GR, FG, GG, MG), insecticidal articles (e.g. LN), as well as gel formulations for the treatment of plant propagation materials such as seeds (e.g. GF). These and further compositions types are defined in the "Catalogue of pesticide formulation types and international coding system", Technical Monograph No. 2, 6th Ed. May 2008, CropLife International.

The compositions are prepared in a known manner, such as described by Mollet and Grubemann, Formulation technology, Wiley VCH, Weinheim, 2001 ; or Knowles, New developments in crop protection product formulation, Agrow Reports DS243, T&F Informa, London, 2005.

Suitable auxiliaries are solvents, liquid carriers, solid carriers or fillers, surfactants, dispersants, emulsifiers, wetters, adjuvants, solubilizers, penetration enhancers, protective colloids, adhesion agents, thickeners, humectants, repellents, attractants, feeding stimulants, compatibilizers, bactericides, anti-freezing agents, anti-foaming agents, colorants, tackifiers and binders. Suitable solvents and liquid carriers are water and organic solvents, such as mineral oil fractions of medium to high boiling point, e.g. kerosene, diesel oil; oils of vegetable or animal origin; aliphatic, cyclic and aromatic hydrocarbons, e. g. toluene, paraffin, tetrahydronaphthalene, alkylated naphthalenes; alcohols, e.g. ethanol, propanol, butanol, benzylalcohol, cyclohexanol; glycols; DMSO; ketones, e.g. cyclohexanone; esters, e.g. lactates, carbonates, fatty acid esters, gamma-butyrolactone; fatty acids; phosphonates; amines; amides, e.g. N-methylpyrrolidone, fatty acid dimethylamides; and mixtures thereof.

Suitable solid carriers or fillers are mineral earths, e.g. silicates, silica gels, talc, kaolins, limestone, lime, chalk, clays, dolomite, diatomaceous earth, bentonite, calcium sulfate, magnesium sulfate, magnesium oxide; polysaccharides, e.g. cellulose, starch; fertilizers, e.g. ammonium sulfate, ammonium phosphate, ammonium nitrate, ureas; products of vegetable origin, e.g. cereal meal, tree bark meal, wood meal, nutshell meal, and mixtures thereof.

Suitable surfactants are surface-active compounds, such as anionic, cationic, nonionic and amphoteric surfactants, block polymers, polyelectrolytes, and mixtures thereof. Such surfactants can be used as emusifier, dispersant, solubilizer, wetter, penetration enhancer, protective colloid, or adjuvant. Examples of surfactants are listed in

McCutcheon's, Vol.1 : Emulsifiers & Detergents, McCutcheon's Directories, Glen Rock, USA, 2008 (International Ed. or North American Ed.).

Suitable anionic surfactants are alkali, alkaline earth or ammonium salts of sulfonates, sulfates, phosphates, carboxylates, and mixtures thereof. Examples of sulfonates are alkylarylsulfonates, diphenylsulfonates, alpha-olefin sulfonates, lignine sulfonates, sulfonates of fatty acids and oils, sulfonates of ethoxylated alkylphenols, sulfonates of alkoxylated arylphenols, sulfonates of condensed naphthalenes, sulfonates of dodecyl- and tridecylbenzenes, sulfonates of naphthalenes and alkylnaphthalenes,

sulfosuccinates or sulfosuccinamates. Examples of sulfates are sulfates of fatty acids and oils, of ethoxylated alkylphenols, of alcohols, of ethoxylated alcohols, or of fatty acid esters. Examples of phosphates are phosphate esters. Examples of carboxylates are alkyl carboxylates, and carboxylated alcohol or alkylphenol ethoxylates.

Suitable nonionic surfactants are alkoxylates, N-subsituted fatty acid amides, amine oxides, esters, sugar-based surfactants, polymeric surfactants, and mixtures thereof. Examples of alkoxylates are compounds such as alcohols, alkylphenols, amines, amides, arylphenols, fatty acids or fatty acid esters which have been alkoxylated with 1 to 50 equivalents. Ethylene oxide and/or propylene oxide may be employed for the alkoxylation, preferably ethylene oxide. Examples of N-subsititued fatty acid amides are fatty acid glucamides or fatty acid alkanolamides. Examples of esters are fatty acid esters, glycerol esters or monoglycerides. Examples of sugar-based surfactants are sorbitans, ethoxylated sorbitans, sucrose and glucose esters or alkylpolyglucosides. Examples of polymeric surfactants are home- or copolymers of vinylpyrrolidone, vinylalcohols, or vinylacetate.

Suitable cationic surfactants are quaternary surfactants, for example quaternary ammonium compounds with one or two hydrophobic groups, or salts of long-chain primary amines. Suitable amphoteric surfactants are alkylbetains and imidazolines. Suitable block polymers are block polymers of the A-B or A-B-A type comprising blocks of polyethylene oxide and polypropylene oxide, or of the A-B-C type comprising alkanol, polyethylene oxide and polypropylene oxide. Suitable polyelectrolytes are polyacids or polybases. Examples of polyacids are alkali salts of polyacrylic acid or polyacid comb polymers. Examples of polybases are polyvinylamines or polyethyleneamines.

Suitable adjuvants are compounds, which have a neglectable or even no pesticidal activity themselves, and which improve the biological performance of the compound I on the target. Examples are surfactants, mineral or vegetable oils, and other auxilaries. Further examples are listed by Knowles, Adjuvants and additives, Agrow Reports DS256, T&F Informa UK, 2006, chapter 5.

Suitable thickeners are polysaccharides (e.g. xanthan gum, carboxymethylcellulose), anorganic clays (organically modified or unmodified), polycarboxylates, and silicates.

Suitable bactericides are bronopol and isothiazolinone derivatives such as alkyliso- thiazolinones and benzisothiazolinones.

Suitable anti-freezing agents are ethylene glycol, propylene glycol, urea and glycerin.

Suitable anti-foaming agents are silicones, long chain alcohols, and salts of fatty acids.

Suitable colorants (e.g. in red, blue, or green) are pigments of low water solubility and water-soluble dyes. Examples are inorganic colorants (e.g. iron oxide, titan oxide, iron hexacyanoferrate) and organic colorants (e.g. alizarin-, azo- and phthalocyanine colorants).

Suitable tackifiers or binders are polyvinylpyrrolidone, polyvinylacetates, polyvinyl alcohols, polyacrylates, biological or synthetic waxes, and cellulose ethers. Examples for composition types and their preparation are:

i) Water-soluble concentrates (SL, LS)

10-60 wt% of a compound I and 5-15 wt% wetting agent (e.g. alcohol alkoxylates) are dissolved in water and/or in a water-soluble solvent (e.g. alcohols) ad 100 wt%. The active substance dissolves upon dilution with water.

ii) Dispersible concentrates (DC)

5-25 wt% of a compound I and 1 -10 wt% dispersant (e. g. polyvinylpyrrolidone) are dissolved in organic solvent (e.g. cyclohexanone) ad 100 wt%. Dilution with water gives a dispersion.

iii) Emulsifiable concentrates (EC)

15-70 wt% of a compound I and 5-10 wt% emulsifiers (e.g. calcium dodecylben- zenesulfonate and castor oil ethoxylate) are dissolved in water-insoluble organic solvent (e.g. aromatic hydrocarbon) ad 100 wt%. Dilution with water gives an emulsion. iv) Emulsions (EW, EO, ES)

5-40 wt% of a compound I and 1 -10 wt% emulsifiers (e.g. calcium dodecylbenzene- sulfonate and castor oil ethoxylate) are dissolved in 20-40 wt% water-insoluble organic solvent (e.g. aromatic hydrocarbon). This mixture is introduced into water ad 100 wt% by means of an emulsifying machine and made into a homogeneous emulsion. Dilution with water gives an emulsion. v) Suspensions (SC, OD, FS)

In an agitated ball mill, 20-60 wt% of a compound I are comminuted with addition of 2- 10 wt% dispersants and wetting agents (e.g. sodium lignosulfonate and alcohol ethoxylate), 0.1 -2 wt% thickener (e.g. xanthan gum) and water ad 100 wt% to give a fine active substance suspension. Dilution with water gives a stable suspension of the active substance. For FS type composition up to 40 wt% binder (e.g. polyvinylalcohol) is added.

vi) Water-dispersible granules and water-soluble granules (WG, SG)

50-80 wt% of a compound I are ground finely with addition of dispersants and wetting agents (e.g. sodium lignosulfonate and alcohol ethoxylate) ad 100 wt% and prepared as water-dispersible or water-soluble granules by means of technical appliances (e. g. extrusion, spray tower, fluidized bed). Dilution with water gives a stable dispersion or solution of the active substance.

vii) Water-dispersible powders and water-soluble powders (WP, SP, WS)

50-80 wt% of a compound I are ground in a rotor-stator mill with addition of 1 -5 wt% dispersants (e.g. sodium lignosulfonate), 1 -3 wt% wetting agents (e.g. alcohol ethoxylate) and solid carrier (e.g. silica gel) ad 100 wt%. Dilution with water gives a stable dispersion or solution of the active substance.

viii) Gel (GW, GF)

In an agitated ball mill, 5-25 wt% of a compound I are comminuted with addition of 3-10 wt% dispersants (e.g. sodium lignosulfonate), 1 -5 wt% thickener (e.g. carboxy- methylcellulose) and water ad 100 wt% to give a fine suspension of the active substance. Dilution with water gives a stable suspension of the active substance.

ix) Microemulsion (ME)

5-20 wt% of a compound I are added to 5-30 wt% organic solvent blend (e.g. fatty acid dimethylamide and cyclohexanone), 10-25 wt% surfactant blend (e.g. alcohol ethoxylate and arylphenol ethoxylate), and water ad 100 %. This mixture is stirred for 1 h to produce spontaneously a thermodynamically stable microemulsion.

x) Microcapsules (CS)

An oil phase comprising 5-50 wt% of a compound I, 0-40 wt% water insoluble organic solvent (e.g. aromatic hydrocarbon), 2-15 wt% acrylic monomers (e.g. methylmethac- rylate, methacrylic acid and a di- or triacrylate) are dispersed into an aqueous solution of a protective colloid (e.g. polyvinyl alcohol). Radical polymerization initiated by a radical initiator results in the formation of poly(meth)acrylate microcapsules. Alternatively, an oil phase comprising 5-50 wt% of a compound I according to the invention, 0-40 wt% water insoluble organic solvent (e.g. aromatic hydrocarbon), and an isocyanate monomer (e.g. diphenylmethene-4,4'-diisocyanatae) are dispersed into an aqueous solution of a protective colloid (e.g. polyvinyl alcohol). The addition of a polyamine (e.g. hexamethylenediamine) results in the formation of polyurea microcapsules. The mono- mers amount to 1 -10 wt%. The wt% relate to the total CS composition.

xi) Dustable powders (DP, DS)

1 -10 wt% of a compound I are ground finely and mixed intimately with solid carrier (e.g. finely divided kaolin) ad 100 wt%. xii) Granules (GR, FG)

0.5-30 wt% of a compound I is ground finely and associated with solid carrier (e.g. silicate) ad 100 wt%. Granulation is achieved by extrusion, spray-drying or fluidized bed.

xiii) Ultra-low volume liquids (UL)

1 -50 wt% of a compound I are dissolved in organic solvent (e.g. aromatic hydrocarbon) ad 100 wt%.

The compositions types i) to xiii) may optionally comprise further auxiliaries, such as 0.1 -1 wt% bactericides, 5-15 wt% anti-freezing agents, 0.1 -1 wt% anti-foaming agents, and 0.1 -1 wt% colorants.

The agrochemical compositions generally comprise between 0.01 and 95%, preferably between 0.1 and 90%, and in particular between 0.5 and 75%, by weight of active substance. The active substances are employed in a purity of from 90% to 100%, preferably from 95% to 100% (according to NMR spectrum).

Solutions for seed treatment (LS), Suspoemulsions (SE), flowable concentrates (FS), powders for dry treatment (DS), water-dispersible powders for slurry treatment (WS), water-soluble powders (SS), emulsions (ES), emulsifiable concentrates (EC) and gels (GF) are usually employed for the purposes of treatment of plant propagation materials, particularly seeds. The compositions in question give, after two-to-tenfold dilution, active substance concentrations of from 0.01 to 60% by weight, preferably from 0.1 to 40%, in the ready-to-use preparations. Application can be carried out before or during sowing. Methods for applying compound I and compositions thereof, respectively, on to plant propagation material, especially seeds include dressing, coating, pelleting, dusting, soaking and in-furrow application methods of the propagation material.

Preferably, compound I or the compositions thereof, respectively, are applied on to the plant propagation material by a method such that germination is not induced, e. g. by seed dressing, pelleting, coating and dusting. When employed in plant protection, the amounts of active substances applied are, depending on the kind of effect desired, from 0.001 to 2 kg per ha, preferably from 0.005 to 2 kg per ha, more preferably from 0.05 to 0.9 kg per ha, and in particular from 0.1 to 0.75 kg per ha.

In treatment of plant propagation materials such as seeds, e. g. by dusting, coating or drenching seed, amounts of active substance of from 0.1 to 1000 g, preferably from 1 to 1000 g, more preferably from 1 to 100 g and most preferably from 5 to 100 g, per 100 kilogram of plant propagation material (preferably seeds) are generally required. When used in the protection of materials or stored products, the amount of active substance applied depends on the kind of application area and on the desired effect. Amounts customarily applied in the protection of materials are 0.001 g to 2 kg, preferably 0.005 g to 1 kg, of active substance per cubic meter of treated material. Various types of oils, wetters, adjuvants, fertilizer, or micronutrients, and further pesticides (e.g. herbicides, insecticides, fungicides, growth regulators, safeners, biopesticides) may be added to the active substances or the compositions comprising them as premix or, if appropriate not until immediately prior to use (tank mix). These agents can be admixed with the compositions according to the invention in a weight ratio of 1 :100 to 100:1 , preferably 1 :10 to 10:1.

A pesticide is generally a chemical or biological agent (such as a virus, bacterium, antimicrobial or disinfectant) that through its effect deters, incapacitates, kills or otherwise discourages pests. Target pests can include insects, plant pathogens, weeds, mollusks, birds, mammals, fish, nematodes (roundworms), and microbes that destroy property, cause nuisance, spread disease or are vectors for disease. The term pesticides includes also plant growth regulators that alter the expected growth, flowering, or reproduction rate of plants; defoliants that cause leaves or other foliage to drop from a plant, usually to facilitate harvest; desiccants that promote drying of living tissues, such as unwanted plant tops; plant activators that activate plant physiology for defense of against certain pests; safeners that reduce unwanted herbicidal action of pesticides on crop plants; and plant growth promoters that affect plant physiology to increase plant growth, biomass, yield or any other quality parameter of the harvestable goods of acrop plant.

Biopesticides are typically created by growing and concentrating naturally occurring organisms and/or their metabolites including bacteria and other microbes, fungi, viruses, nematodes, proteins, etc. They are often considered to be important components of integrated pest management (IPM) programmes.

Biopesticides fall into two major classes, microbial and biochemical pesticides:

(1 ) Microbial pesticides consist of bacteria, fungi or viruses (and often include the metabolites that bacteria and fungi produce). Entomopathogenic nematodes are also classed as microbial pesticides, even though they are multi-cellular.

(2) Biochemical pesticides are naturally occurring substances that control pests or provide other crop protection uses as defined below, but are relatively non-toxic to mammals.

The user applies the composition according to the invention usually from a predosage device, a knapsack sprayer, a spray tank, a spray plane, or an irrigation system.

Usually, the agrochemical composition is made up with water, buffer, and/or further auxiliaries to the desired application concentration and the ready-to-use spray liquor or the agrochemical composition according to the invention is thus obtained. Usually, 20 to 2000 liters, preferably 50 to 400 liters, of the ready-to-use spray liquor are applied per hectare of agricultural useful area.

According to one embodiment, individual components of the composition according to the invention such as parts of a kit or parts of a binary or ternary mixture may be mixed by the user himself in a spray tank or any other kind of vessel used for applications (e.g seed treater drums, seed pelleting machinery, knapsack sprayer) and further auxiliaries may be added, if appropriate. When living microorganisms, such as pesticides from groups L1 ), L3) and L5), form part of such kit, it must be taken care that choice and amounts of the components (e.g. chemcial pesticidal agents) and of the further auxiliaries should not influence the viability of the microbial pesticides in the composition mixed by the user. Especially for bactericides and solvents, compatibility with the respective microbial pesticide has to be taken into account.

Consequently, one embodiment of the invention is a kit for preparing a usable pesticidal composition, the kit compring a) a composition comprising component 1 ) as defined herein and at least one auxiliary; and b) a composition comprising component 2) as defined herein and at least one auxiliary; and optionally c) a composition comprising at least one auxiliary and optionally a further active component 3) as defined herein.

Mixing the compounds I or the compositions comprising them in the use form as fungicides with other fungicides results in many cases in an expansion of the fungicidal spectrum of activity being obtained or in a prevention of fungicide resistance development. Furthermore, in many cases, synergistic effects are obtained.

The following list of pesticides II (e.g. pesticidally-active substances and biopesticides), in conjunction with which the compounds I can be used, is intended to illustrate the possible combinations but does not limit them:

A) Respiration inhibitors

Inhibitors of complex III at Q₀ site (e.g. strobilurins): azoxystrobin (A.1 .1 ), coumethoxystrobin (A.1.2), coumoxystrobin (A.1 .3), dimoxystrobin (A.1 .4), enestroburin (A.1 .5), fenaminstrobin (A.1 .6), fenoxystrobin/flufenoxystrobin (A.1.7), fluoxastrobin (A.1.8), kresoxim-methyl (A.1 .9), mandestrobin (A.1 .10), metominostrobin (A.1 .1 1 ), orysastrobin (A.1 .12), picoxystrobin (A.1 .13), pyraclostrobin (A.1.14), pyrametostrobin (A.1 .15), pyraoxystrobin (A.1.16), trifloxystrobin (A.1.17) and 2-(2-(3-(2,6-dichlorophenyl)-1 -methyl-allylidene- aminooxymethyl)-phenyl)-2-methoxyimino-N-methyl-acetamide (A.1 .18), pyribencarb (A.1.19), triclopyricarb/chlorodincarb (A.1.20), famoxadone (A.1.21 ), fenamidone (A.1.21 );

inhibitors of complex III at Qi site: cyazofamid (A.2.1 ), amisulbrom (A.2.2),

[(3S,6S,7R,8R)-8-benzyl-3-[(3-acetoxy-4-methoxy-pyridine-2-carbonyl)amino]- 6-methyl-4,9-dioxo-1 ,5-dioxonan-7-yl] 2-methylpropanoate (A.2.3),

[(3S,6S,7R,8R)-8-benzyl-3-[[3-(acetoxymethoxy)-4-methoxy-pyridine- 2-carbonyl]amino]-6-methyl-4,9-dioxo-1 ,5-dioxonan-7-yl] 2-methylpropanoate (A.2.4), [(3S,6S,7R,8R)-8-benzyl-3-[(3-isobutoxycarbonyloxy-4-methoxy-pyridine- 2-carbonyl)amino]-6-methyl-4,9-dioxo-1 ,5-dioxonan-7-yl] 2-methylpropanoate (A.2.5), [(3S,6S,7R,8R)-8-benzyl-3-[[3-(1 ,3-benzodioxol-5-ylmethoxy)-4-methoxy- pyridine-2-carbonyl]amino]-6-methyl-4,9-dioxo-1 ,5-dioxonan-7-yl] 2-methylpropanoate (A.2.6); (3S,6S,7R,8R)-3-[[(3-hydroxy-4-methoxy-2- pyridinyl)carbonyl]amino]-6-methyl-4,9-dioxo-8-(phenylmethyl)-1 ,5-dioxonan-7-yl 2-methylpropanoate (A.2.7); inhibitors of complex II (e. g. carboxamides): benodanil (A.3.1 ), benzovindiflupyr (A.3.2), bixafen (A.3.3), boscalid (A.3.4), carboxin (A.3.5), fenfuram (A.3.6), fluopyram (A.3.7), flutolanil (A.3.8), fluxapyroxad (A.3.9), furametpyr (A.3.10), isofetamid (A.3.1 1 ), isopyrazam (A.3.12), mepronil (A.3.13), oxycarboxin

(A.3.14), penflufen (A.3.14), penthiopyrad (A.3.15), sedaxane (A.3.16), tecloftalam (A.3.17), thifluzamide (A.3.18), N-(4'-trifluoromethylthiobiphenyl-2-yl)-

3- difluoromethyl-1 -methyl-1 H-pyrazole-4-carboxamide (A.3.19), N-(2-(1 ,3,3- trimethyl-butyl)-phenyl)-1 ,3-dimethyl-5-fluoro-1 H-pyrazole-4-carboxamide (A.3.20), 3-(difluoromethyl)-1 -methyl-N-(1 ,1 ,3-trimethylindan-4-yl)pyrazole-4- carboxamide (A.3.21 ), 3-(trifluoromethyl)-1 -methyl-N-(1 ,1 ,3-trimethylindan-4- yl)pyrazole-4-carboxamide (A.3.22), 1 ,3-dimethyl-N-(1 ,1 ,3-trimethylindan-4- yl)pyrazole-4-carboxamide (A.3.23), 3-(trifluoromethyl)-1 ,5-dimethyl-N-(1 ,1 ,3- trimethylindan-4-yl)pyrazole-4-carboxamide (A.3.24), 1 ,3,5-trimethyl-N-(1 ,1 ,3- trimethylindan-4-yl)pyrazole-4-carboxamide (A.3.25), N-(7-fluoro-1 ,1 ,3-trimethyl- indan-4-yl)-1 ,3-dimethyl-pyrazole-4-carboxamide (A.3.26), N-[2-(2,4- dichlorophenyl)-2-methoxy-1 -methyl-ethyl]-3-(difluoromethyl)-1 -methyl-pyrazole-

4- carboxamide (A.3.27);

other respiration inhibitors (e.g. complex I, uncouplers): diflumetorim (A.4.1 ), (5,8- difluoroquinazolin-4-yl)-{2-[2-fluoro-4-(4-trifluoromethylpyridin-2-yloxy)-phenyl]- ethyl}-amine (A.4.2); nitrophenyl derivates: binapacryl (A.4.3), dinobuton (A.4.4), dinocap (A.4.5), fluazinam (A.4.6); ferimzone (A.4.7); organometal compounds: fentin salts, such as fentin-acetate (A.4.8), fentin chloride (A.4.9) or fentin hydroxide (A.4.10); ametoctradin (A.4.1 1 ); and silthiofam (A.4.12);

B) Sterol biosynthesis inhibitors (SBI fungicides)

- C14 demethylase inhibitors (DMI fungicides): triazoles: azaconazole (B.1 .1 ), bitertanol (B.1.2), bromuconazole (B.1 .3), cyproconazole (B.1.4), difenoconazole (B.1.5), diniconazole (B.1 .6), diniconazole-M (B.1.7), epoxiconazole (B.1 .8), fenbuconazole (B.1.9), fluquinconazole (B.1.10), flusilazole (B.1 .1 1 ), flutriafol (B.1.12), hexaconazole (B.1 .13), imibenconazole (B.1 .14), ipconazole (B.1.15), metconazole (B.1 .17), myclobutanil (B.1 .18), oxpoconazole (B.1.19),

paclobutrazole (B.1 .20), penconazole (B.1.21 ), propiconazole (B.1 .22), prothio- conazole (B.1 .23), simeconazole (B.1 .24), tebuconazole (B.1.25), tetraconazole (B.1.26), triadimefon (B.1.27), triadimenol (B.1 .28), triticonazole (B.1.29), uniconazole (B.1 .30), 1 -[rel-(2S;3R)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)- oxiranylmethyl]-5-thiocyanato-1 H-[1 ,2,4]triazolo (B.1 .31 ), 2-[rel-(2S;3R)-3-(2- chlorophenyl)-2-(2,4-difluorophenyl)-oxiranylmethyl]-2H-[1 ,2,4]triazole-3-thiol (B.1.32), 2-[2-chloro-4-(4-chlorophenoxy)phenyl]-1-(1 ,2,4-triazol-1 -yl)pentan-2-ol (B.1.33), 1 -[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1 -cyclopropyl-2-(1 ,2,4- triazol-1 -yl)ethanol (B.1 .34), 2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1 - (1 ,2,4-triazol-1 -yl)butan-2-ol (B.1 .35), 2-[2-chloro-4-(4-chlorophenoxy)phenyl]-1 -

(1 ,2,4-triazol-1 -yl)butan-2-ol (B.1 .36), 2-[4-(4-chlorophenoxy)-2- (trifluoromethyl)phenyl]-3-methyl-1 -(1 ,2,4-triazol-1-yl)butan-2-ol (B.1 .37), 2-[4-(4- chlorophenoxy)-2-(trifluoromethyl)phenyl]-1 -(1 ,2,4-triazol-1 -yl)propan-2-ol (B.1.38), 2-[2-chloro-4-(4-chlorophenoxy)phenyl]-3-methyl-1 -(1 ,2,4-triazol-1 - yl)butan-2-ol (B.1.39), 2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1 -(1 ,2,4- triazol-1 -yl)pentan-2-ol (B.1 .40), 2-[4-(4-fluorophenoxy)-2-(trifluoromethyl)phenyl]- 1 -(1 ,2,4-triazol-1 -yl)propan-2-ol (B.1.41 ); imidazoles: imazalil (B.1.42), pefurazoate (B.1.43), prochloraz (B.1 .44), triflumizol (B.1.45); pyrimidines, pyridines and piperazines: fenarimol (B.1.46), nuarimol (B.1.47), pyrifenox (B.1.48), triforine (B.1 .49), [3-(4-chloro-2-fluoro-phenyl)-5-(2,4-difluoro- phenyl)isoxazol-4-yl]-(3-pyridyl)methanol (B.1 .50);

Delta14-reductase inhibitors: aldimorph (B.2.1 ), dodemorph (B.2.2), dodemorph- acetate (B.2.3), fenpropimorph (B.2.4), tridemorph (B.2.5), fenpropidin (B.2.6), piperalin (B.2.7), spiroxamine (B.2.8);

Inhibitors of 3-keto reductase: fenhexamid (B.3.1 );

C) Nucleic acid synthesis inhibitors

phenylamides or acyl amino acid fungicides: benalaxyl (C.1.1 ), benalaxyl-M (C.1 .2), kiralaxyl (C.1 .3), metalaxyl (C.1 .4), metalaxyl-M (mefenoxam, C.1 .5), ofurace (C.1 .6), oxadixyl (C.1 .7);

others: hymexazole (C.2.1 ), octhilinone (C.2.2), oxolinic acid (C.2.3), bupirimate (C.2.4), 5-fluorocytosine (C.2.5), 5-fluoro-2-(p-tolylmethoxy)pyrimidin-4-amine (C.2.6), 5-fluoro-2-(4-fluorophenylmethoxy)pyrimidin-4-amine (C.2.7);

D) Inhibitors of cell division and cytoskeleton

tubulin inhibitors, such as benzimidazoles, thiophanates: benomyl (D1 .1 ), carbendazim (D1.2), fuberidazole (D1 .3), thiabendazole (D1 .4), thiophanate- methyl (D1 .5); triazolopyrimidines: 5-chloro-7-(4-methylpiperidin-1 -yl)-6-(2,4,6- trifluorophenyl)-[1 ,2,4]triazolo[1 ,5-a]pyrimidine (D1 .6);

- other cell division inhibitors: diethofencarb (D2.1 ), ethaboxam (D2.2), pencycuron (D2.3), fluopicolide (D2.4), zoxamide (D2.5), metrafenone (D2.6), pyriofenone (D2.7);

E) Inhibitors of amino acid and protein synthesis

methionine synthesis inhibitors (anilino-pyrimidines): cyprodinil (E.1 .1 ), mepani- pyrim (E.1.2), pyrimethanil (E.1.3);

protein synthesis inhibitors: blasticidin-S (E.2.1 ), kasugamycin (E.2.2), kasugamycin hydrochloride-hydrate (E.2.3), mildiomycin (E.2.4), streptomycin (E.2.5), oxytetracyclin (E.2.6), polyoxine (E.2.7), validamycin A (E.2.8);

F) Signal transduction inhibitors

- MAP / histidine kinase inhibitors: fluoroimid (F.1 .1 ), iprodione (F.1 .2),

procymidone (F.1.3), vinclozolin (F.1 .4), fenpiclonil (F.1 .5), fludioxonil (F.1 .6); G protein inhibitors: quinoxyfen (F.2.1 );

G) Lipid and membrane synthesis inhibitors

Phospholipid biosynthesis inhibitors: edifenphos (G.1 .1 ), iprobenfos (G.1 .2), pyrazophos (G.1 .3), isoprothiolane (G.1.4);

lipid peroxidation: dicloran (G.2.1 ), quintozene (G.2.2), tecnazene (G.2.3), tolclofos-methyl (G.2.4), biphenyl (G.2.5), chloroneb (G.2.6), etridiazole (G.2.7); phospholipid biosynthesis and cell wall deposition: dimethomorph (G.3.1 ), flumorph (G.3.2), mandipropamid (G.3.3), pyrimorph (G.3.4), benthiavalicarb (G.3.5), iprovalicarb (G.3.6), valifenalate (G.3.7) and N-(1 -(1 -(4-cyano-phenyl)- ethanesulfonyl)-but-2-yl) carbamic acid-(4-fluorophenyl) ester (G.3.8);

- compounds affecting cell membrane permeability and fatty acides: propamocarb (G.4.1 );

fatty acid amide hydrolase inhibitors: oxathiapiprolin (G.5.1 ), 2-{3-[2-(1 -{[3,5- bis(difluoromethyl-1 H-pyrazol-1 -yl]acetyl}piperidin-4-yl)-1 ,3-thiazol-4-yl]-4,5- dihydro-1 ,2-oxazol-5-yl}phenyl methanesulfonate (G.5.2), 2-{3-[2-(1 -{[3,5- bis(difluoromethyl)-1 H-pyrazol-1 -yl]acetyl}piperidin-4-yl) 1 ,3-thiazol-4-yl]-4,5- dihydro-1 ,2-oxazol-5-yl}-3-chlorophenyl methanesulfonate (G.5.3);

H) Inhibitors with Multi Site Action

inorganic active substances: Bordeaux mixture (H.1 .1 ), copper acetate (H.1.2), copper hydroxide (H.1.3), copper oxychloride (H.1.4), basic copper sulfate (H.1 .5), sulfur (H.1.6);

thio- and dithiocarbamates: ferbam (H.2.1 ), mancozeb (H.2.2), maneb (H.2.3), metam (H.2.4), metiram (H.2.5), propineb (H.2.6), thiram (H.2.7), zineb (H.2.8), ziram (H.2.9);

organochlorine compounds (e.g. phthalimides, sulfamides, chloronitriles):

anilazine (H.3.1 ), chlorothalonil (H.3.2), captafol (H.3.3), captan (H.3.4), folpet

(H.3.5), dichlofluanid (H.3.6), dichlorophen (H.3.7), hexachlorobenzene (H.3.8), pentachlorphenole (H.3.9) and its salts, phthalide (H.3.10), tolylfluanid (H.3.1 1 ), N-(4-chloro-2-nitro-phenyl)-N-ethyl-4-methyl-benzenesulfonamide (H.3.12); guanidines and others: guanidine (H.4.1 ), dodine (H.4.2), dodine free base (H.4.3), guazatine (H.4.4), guazatine-acetate (H.4.5), iminoctadine (H.4.6), iminoctadine-triacetate (H.4.7), iminoctadine-tris(albesilate) (H.4.8), dithianon (H.4.9), 2,6-dimethyl-1 H,5H-[1 ,4]dithiino[2,3-c:5,6-c']dipyrrole-1 ,3,5,7(2H,6H)- tetraone (H.4.10);

I) Cell wall synthesis inhibitors

- inhibitors of glucan synthesis: validamycin (1.1.1 ), polyoxin B (1.1 .2);

melanin synthesis inhibitors: pyroquilon (1.2.1 ), tricyclazole (1.2.2), carpropamid

(I.2.3), dicyclomet (I.2.4), fenoxanil (I.2.5);

J) Plant defence inducers

acibenzolar-S-methyl (J.1.1 ), probenazole (J.1 .2), isotianil (J.1 .3), tiadinil (J.1.4), prohexadione-calcium (J.1.5); phosphonates: fosetyl (J.1 .6), fosetyl-aluminum

(J.1.7), phosphorous acid and its salts (J.1 .8), potassium or sodium bicarbonate

(J.1 .9);

K) Unknown mode of action

bronopol (K.1.1 ), chinomethionat (K.1 .2), cyflufenamid (K.1.3), cymoxanil (K.1 .4), dazomet (K.1 .5), debacarb (K.1.6), diclomezine (K.1 .7), difenzoquat (K.1 .8), difenzoquat-methylsulfate (K.1.9), diphenylamin (K.1 .10), fenpyrazamine

(K.1.1 1 ), flumetover (K.1 .12), flusulfamide (K.1.13), flutianil (K.1.14),

methasulfocarb (K.1 .15), nitrapyrin (K.1 .16), nitrothal-isopropyl (K.1.18), oxathiapiprolin (K.1 .19), tolprocarb (K.1 .20), oxin-copper (K.1 .21 ), proquinazid (K.1.22), tebufloquin (K.1 .23), tecloftalam (K.1.24), triazoxide (K.1 .25), 2-butoxy- 6-iodo-3-propylchromen-4-one (K.1.26), 2-[3,5-bis(difluoromethyl)-1 H-pyrazol-1 - _y|]-1 -[4-(4-{5-[2-(prop-2-yn-1 -yloxy)phenyl]-4,5-dihydro-1 ,2-oxazol-3-yl}-1 ,3- thiazol-2-yl)piperidin-1 -yl]ethanone (K.1.27), 2-[3,5-bis(difluoromethyl)-1 H- pyrazol-1 -yl]-1 -[4-(4-{5-[2-fluoro-6-(prop-2-yn-1 -yloxy)phenyl]-4,5-dihydro-1 ,2- oxazol-3-yl}-1 ,3-thiazol-2-yl)piperidin-1 -yl]ethanone (K.1 .28), 2-[3,5- bis(difluoromethyl)-1 H-pyrazol-1 -yl]-1 -[4-(4-{5-[2-chloro-6-(prop-2-yn-1 -yl- oxy)phenyl]-4,5-dihydro-1 ,2-oxazol-3-yl}-1 ,3-thiazol-2-yl)piperidin-1 -yl]ethanone (K.1.29), N-(cyclopropylmethoxyimino-(6-difluoro-methoxy-2,3-difluoro-phenyl)- methyl)-2-phenyl acetamide (K.1 .30), N'-(4-(4-chloro-3-trifluoromethyl-phenoxy)- 2,5-dimethyl-phenyl)-N-ethyl-N-methyl formamidine (K.1 .31 ), N'-(4-(4-fluoro-3- trifluoromethyl-phenoxy)-2,5-dimethyl-phenyl)-N-ethyl-N-methyl formamidine (K.1.32), N'-(2-methyl-5-trifluoromethyl-4-(3-trimethylsilanyl-propoxy)-phenyl)-N- ethyl-N-methyl formamidine (K.1.33), N'-(5-difluoromethyl-2-methyl-4-(3-tri- methylsilanyl-propoxy)-phenyl)-N-ethyl-N-methyl formamidine (K.1.34), methoxy- acetic acid 6-tert-butyl-8-fluoro-2,3-dimethyl-quinolin-4-yl ester (K.1 .35), 3-[5-(4- methylphenyl)-2,3-dimethyl-isoxazolidin-3-yl]-pyridine (K.1 .36), 3-[5-(4-chloro- phenyl)-2,3-dimethyl-isoxazolidin-3-yl]-pyridine (pyrisoxazole) (K.1 .37), N-(6- methoxy-pyridin-3-yl) cyclopropanecarboxylic acid amide (K.1 .38), 5-chloro- 1 -(4,6-dimethoxy-pyrimidin-2-yl)-2-methyl-1 H-benzoimidazole (K.1.39), 2-(4- chloro-phenyl)-N-[4-(3,4-dimethoxy-phenyl)-isoxazol-5-yl]-2-prop-2-ynyloxy- acetamide, ethyl (Z)-3-amino-2-cyano-3-phenyl-prop-2-enoate (K.1.40), picarbutrazox (K.1.41 ), pentyl N-[6-[[(Z)-[(1 -methyltetrazol-5-yl)-phenyl- methylene]amino]oxymethyl]-2-pyridyl]carbamate (K.1 .42), 2-[2-[(7,8-difluoro-2- methyl-3-quinolyl)oxy]-6-fluoro-phenyl]propan-2-ol (K.1 .43), 2-[2-fluoro-6-[(8- fluoro-2-methyl-3-quinolyl)oxy]phen-yl]propan-2-ol (K.1 .44), 3-(5-fluoro-3,3,4,4- tetramethyl-3,4-dihydroisoquinolin-1 -yl)quinoline (K.1.45), 3-(4,4-difluoro-3,3- dimethyl-3,4-dihydroisoquinolin-1 -yl)quinoline (K.1 .46), 3-(4,4,5-trifluoro-3,3- dimethyl-3,4-dihydroisoquinolin-1 -yl)quinoline (K.1 .47);

Biopesticides

L1 ) Microbial pesticides with fungicidal, bactericidal, viricidal and/or plant

defense activator activity: Ampelomyces quisqualis, Aspergillus flavus, Aureobasidium pullulans, Bacillus amyloliquefaciens, B. mojavensis, B. pumilus, B. simplex, B. solisalsi, B. subtilis, B. subtilis var.

amyloliquefaciens, Candida oleophila, C. saitoana, Clavibacter

michiganensis (bacteriophages), Coniothyrium minitans, Cryphonectria parasitica, Cryptococcus albidus, Dilophosphora alopecuri, Fusarium oxysporum, Clonostachys rosea f. catenulate (also named Gliocladium catenulatum), Gliocladium roseum, Lysobacter antibioticus, L.

enzymogenes, Metschnikowia fructicola, Microdochium dimerum,

Microsphaeropsis ochracea, Muscodor albus, Paenibacillus polymyxa, Pantoea vagans, Phlebiopsis gigantea, Pseudomonas sp., Pseudomonas chloraphis, Pseudozyma flocculosa, Pichia anomala, Pythium oligandrum, Sphaerodes mycoparasitica, Streptomyces griseoviridis, S. lydicus, S. violaceusniger, Talaromyces flavus, Trichoderma asperellum, T. atroviride, T. fertile, T. gamsii, T. harmatum, T. harzianum; mixture of T. harzianum and T. viride; mixture of T. polysporum and T. harzianum; T. stromaticum, T. virens (also named Gliocladium virens), T. viride, Typhula phacorrhiza, Ulocladium oudemansii, Verticillium dahlia, zucchini yellow mosaic virus (avirulent strain);

Biochemical pesticides with fungicidal, bactericidal, viricidal and/or plant defense activator activity: chitosan (hydrolysate), harpin protein, laminarin, Menhaden fish oil, natamycin, Plum pox virus coat protein, potassium or sodium bicarbonate, Reynoutria sachlinensis extract, salicylic acid, tea tree oil;

Microbial pesticides with insecticidal, acaricidal, molluscidal and/or nematicidal activity: Agrobacterium radiobacter, Bacillus cereus, B. firmus, B. thuringiensis, B. thuringiensis ssp. aizawai, B. t. ssp. israelensis, B. t. ssp. galleriae, B. t. ssp. kurstaki, B. t. ssp. tenebrionis, Beauveria bassiana, B. brongniartii , Burkholderia sp., Chromobacterium subtsugae, Cydia pomonella granulosis virus, Cryptophlebia leucotreta granulovirus (CrleGV), Isaria fumosorosea, Heterorhabditis bacteriophora, Lecanicillium

longisporum, L. muscarium (formerly Verticillium lecanii), Metarhizium anisopliae, M. anisopliae var. acridum, Nomuraea rileyi, Paecilomyces fumosoroseus, P. lilacinus, Paenibacillus popilliae, Pasteuria spp., P.

nishizawae, P. penetrans, P. ramose, P. reneformis, P. thornea, P. usgae, Pseudomonas fluorescens, Steinernema carpocapsae, S. feltiae, S.

kraussei;

Biochemical pesticides with insecticidal, acaricidal, molluscidal, pheromone and/or nematicidal activity: L-carvone, citral, (E,Z)-7,9-dodecadien-1 -yl acetate, ethyl formate, (E,Z)-2,4-ethyl decadienoate (pear ester), (Ζ,Ζ,Ε)- 7,1 1 ,13-hexadecatrienal, heptyl butyrate, isopropyl myristate, lavanulyl senecioate, cis-jasmone, 2-methyl 1 -butanol, methyl eugenol, methyl jasmonate, (E,Z)-2,13-octadecadien-1 -ol, (E,Z)-2, 13-octadecadien-1 -ol acetate, (E,Z)-3,13-octadecadien-1 -ol, R-1 -octen-3-ol, pentatermanone, potassium silicate, sorbitol actanoate, (E,Z,Z)-3,8,1 1 -tetradecatrienyl acetate, (Z,E)-9,12-tetradecadien-1 -yl acetate, Z-7-tetradecen-2-one, Z-9- tetradecen-1 -yl acetate, Z-1 1 -tetradecenal, Z-1 1 -tetradecen-1 -ol, Acacia negra extract, extract of grapefruit seeds and pulp, extract of Chenopodium ambrosiodae, Catnip oil, Neem oil, Quillay extract, Tagetes oil;

Microbial pesticides with plant stress reducing, plant growth regulator, plant growth promoting and/or yield enhancing activity: Azospirillum

amazonense, A. brasilense, A. lipoferum, A. irakense, A. halopraeferens, Bradyrhizobium sp., B. elkanii, B. japonicum, B. liaoningense, B. lupini, Delftia acidovorans, Glomus intraradices, Mesorhizobium sp., Paenibacillus alvei, Penicillium bilaiae, Rhizobium leguminosarum bv. phaseoli, R. I. trifolii, R. I. bv. viciae, R. tropici, Sinorhizobium meliloti;

L6) Biochemical pesticides with plant stress reducing, plant growth regulator and/or plant yield enhancing activity: abscisic acid, aluminium silicate (kaolin), 3-decen-2-one, formononetin, genistein, hesperetin,

homobrassinlide, humates, jasmonic acid or salts or derivatives thereof, lysophosphatidyl ethanolamine, naringenin, polymeric polyhydroxy acid, Ascophyllum nodosum (Norwegian kelp, Brown kelp) extract and Ecklonia maxima (kelp) extract;

M) Growth regulators

abscisic acid (M.1.1 ), amidochlor, ancymidol, 6-benzylaminopurine, brassinolide, butralin, chlormequat (chlormequat chloride), choline chloride, cyclanilide, daminozide, dikegulac, dimethipin, 2,6-dimethylpuridine, ethephon, flumetralin, flurprimidol, fluthiacet, forchlorfenuron, gibberellic acid, inabenfide, indole-3- acetic acid , maleic hydrazide, mefluidide, mepiquat (mepiquat chloride), naphthaleneacetic acid, N-6-benzyladenine, paclobutrazol, prohexadione

(prohexadione-calcium), prohydrojasmon, thidiazuron, triapenthenol, tributyl phosphorotrithioate, 2,3,5-tri-iodobenzoic acid , trinexapac-ethyl and uniconazole; N) Herbicides

- acetamides: acetochlor (N.1 .1 ), alachlor, butachlor, dimethachlor, dimethenamid (N.1 .2), flufenacet (N.1 .3), mefenacet (N.1.4), metolachlor (N.1.5), metazachlor (N.1 .6), napropamide, naproanilide, pethoxamid, pretilachlor, propachlor, thenylchlor;

amino acid derivatives: bilanafos, glyphosate (N.2.1 ), glufosinate (N.2.2), sulfosate (N.2.3);

aryloxyphenoxypropionates: clodinafop (N.3.1 ), cyhalofop-butyl, fenoxaprop

(N.3.2), fluazifop (N.3.3), haloxyfop (N.3.4), metamifop, propaquizafop, quizalofop, quizalofop-P-tefuryl;

Bipyridyls: diquat, paraquat (N.4.1 );

- (thio)carbamates: asulam, butylate, carbetamide, desmedipham, dimepiperate, eptam (EPTC), esprocarb, molinate, orbencarb, phenmedipham (N.5.1 ), prosulfocarb, pyributicarb, thiobencarb, triallate;

cyclohexanediones: butroxydim, clethodim (N.6.1 ), cycloxydim (N.6.2), profoxydim (N.6.3), sethoxydim (N.6.4), tepraloxydim (N.6.5), tralkoxydim;

- dinitroanilines: benfluralin, ethalfluralin, oryzalin, pendimethalin (N.7.1 ),

prodiamine (N.7.2), trifluralin (N.7.3);

diphenyl ethers: acifluorfen (N.8.1 ), aclonifen, bifenox, diclofop, ethoxyfen, fomesafen, lactofen, oxyfluorfen;

hydroxybenzonitriles: bomoxynil (N.9.1 ), dichlobenil, ioxynil;

- imidazolinones: imazamethabenz, imazamox (N.10.1 ), imazapic (N.10.2),

imazapyr (N.10.3), imazaquin (N.10.4), imazethapyr (N.10.5);

phenoxy acetic acids: clomeprop, 2,4-dichlorophenoxyacetic acid (2,4-D)

(N.1 1.1 ), 2,4-DB, dichlorprop, MCPA, MCPA-thioethyl, MCPB, Mecoprop; pyrazines: chloridazon (N.1 1.1 ), flufenpyr-ethyl, fluthiacet, norflurazon, pyridate; pyridines: aminopyralid, clopyralid (N.12.1 ), diflufenican, dithiopyr, fluridone, fluroxypyr (N.12.2), picloram (N.12.3), picolinafen (N.12.4), thiazopyr;

sulfonyl ureas: amidosulfuron, azimsulfuron, bensulfuron (N.13.1 ), chlorimuron- ethyl (N.13.2), chlorsulfuron, cinosulfuron, cyclosulfamuron (N.13.3),

ethoxysulfuron, flazasulfuron, flucetosulfuron, flupyrsulfuron, foramsulfuron, halosulfuron, imazosulfuron, iodosulfuron (N.13.4), mesosulfuron (N.13.5), metazosulfuron, metsulfuron-methyl (N.13.6), nicosulfuron (N.13.7), oxasulfuron, primisulfuron, prosulfuron, pyrazosulfuron, rimsulfuron (N.13.8), sulfometuron, sulfosulfuron, thifensulfuron, triasulfuron, tribenuron, trifloxysulfuron, triflusulfuron (N.13.9), tritosulfuron, 1 -((2-chloro-6-propyl-imidazo[1 ,2-b]pyridazin-3-yl)sulfonyl)- 3-(4 , 6-d i methoxy-pyri m id i n-2-yl) u rea ;

triazines: ametryn, atrazine (N.14.1 ), cyanazine, dimethametryn, ethiozin, hexazinone (N.14.2), metamitron, metribuzin, prometryn, simazine,

terbuthylazine, terbutryn, triaziflam;

ureas: chlorotoluron, daimuron, diuron (N.15.1 ), fluometuron, isoproturon, linuron, methabenzthiazuron, tebuthiuron;

other acetolactate synthase inhibitors: bispyribac-sodium, cloransulam-methyl, diclosulam, florasulam (N.16.1 ), flucarbazone, flumetsulam, metosulam, ortho- sulfamuron, penoxsulam, propoxycarbazone, pyribambenz-propyl, pyribenzoxim, pyriftalid, pyriminobac-methyl, pyrimisulfan, pyrithiobac, pyroxasulfone (N.16.2), pyroxsulam;

others: amicarbazone, aminotriazole, anilofos, beflubutamid, benazolin, bencarbazone,benfluresate, benzofenap, bentazone (N.17.1 ), benzobicyclon, bicyclopyrone, bromacil, bromobutide, butafenacil, butamifos, cafenstrole, carfentrazone, cinidon-ethyl (N.17.2), chlorthal, cinmethylin (N.17.3), clomazone (N.17.4), cumyluron, cyprosulfamide, dicamba (N.17.5), difenzoquat,

diflufenzopyr (N.17.6), Drechslera monoceras, endothal, ethofumesate, etobenzanid, fenoxasulfone, fentrazamide, flumiclorac-pentyl, flumioxazin, flupoxam, flurochloridone, flurtamone, indanofan, isoxaben, isoxaflutole, lenacil, propanil, propyzamide, quinclorac (N.17.7), quinmerac (N.17.8), mesotrione (N.17.9), methyl arsonic acid, naptalam, oxadiargyl, oxadiazon, oxaziclomefone, pentoxazone, pinoxaden, pyraclonil, pyraflufen-ethyl, pyrasulfotole, pyrazoxyfen, pyrazolynate, quinoclamine, saflufenacil (N.17.10), sulcotrione (N.17.1 1 ), sulfentrazone, terbacil, tefuryltrione, tembotrione, thiencarbazone, topramezone (N.17.12), (3-[2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6- dihydro-2H-pyrimidin-1 -yl)-phenoxy]-pyridin-2-yloxy)-acetic acid ethyl ester, 6- amino-5-chloro-2-cyclopropyl-pyrimidine-4-carboxylic acid methyl ester, 6-chloro- 3-(2-cyclopropyl-6-methyl-phenoxy)-pyridazin-4-ol, 4-amino-3-chloro-6-(4-chloro- phenyl)-5-fluoro-pyridine-2-carboxylic acid, 4-amino-3-chloro-6-(4-chloro-2-fluoro- 3-methoxy-phenyl)-pyridine-2-carboxylic acid methyl ester, and 4-amino-3-chloro- 6-(4-chloro-3-dimethylamino-2-fluoro-phenyl)-pyridine-2-carboxylic acid methyl ester; ecticides

organo(thio)phosphates: acephate (0.1.1 ), azamethiphos (0.1 .2), azinphos- methyl (0.1.3), chlorpyrifos (0.1 .4), chlorpyrifos-methyl (0.1 .5), chlorfenvinphos (0.1.6), diazinon (0.1 .7), dichlorvos (0.1.8), dicrotophos (0.1.9), dimethoate (0.1.10), disulfoton (0.1 .1 1 ), ethion (0.1.12), fenitrothion (0.1 .13), fenthion

(0.1.14), isoxathion (0.1 .15), malathion (0.1 .16), methamidophos (0.1.17), methidathion (0.1 .18), methyl-parathion (0.1.19), mevinphos (0.1.20), monocrotophos (0.1.21 ), oxydemeton-methyl (0.1 .22), paraoxon (0.1.23), parathion (0.1.24), phenthoate (0.1.25), phosalone (0.1 .26), phosmet (0.1.27), phosphamidon (0.1 .28), phorate (0.1 .29), phoxim (0.1 .30), pirimiphos-methyl

(0.1.31 ), profenofos (0.1.32), prothiofos (0.1 .33), sulprophos (0.1.34), tetrachlorvinphos (0.1.35), terbufos (0.1 .36), triazophos (0.1 .37), trichlorfon (0.1 .38);

carbamates: alanycarb (0.2.1 ), aldicarb (0.2.2), bendiocarb (0.2.3), benfuracarb (0.2.4), carbaryl (0.2.5), carbofuran (0.2.6), carbosulfan (0.2.7), fenoxycarb

(0.2.8), furathiocarb (0.2.9), methiocarb (0.2.10), methomyl (0.2.1 1 ), oxamyl (0.2.12), pirimicarb (0.2.13), propoxur (0.2.14), thiodicarb (0.2.15), triazamate (0.2.16);

pyrethroids: allethrin (0.3.1 ), bifenthrin (0.3.2), cyfluthrin (0.3.3), cyhalothrin (0.3.4), cyphenothrin (0.3.5), cypermethrin (0.3.6), alpha-cypermethrin (0.3.7), beta-cypermethrin (0.3.8), zeta-cypermethrin (0.3.9), deltamethrin (0.3.10), esfenvalerate (0.3.1 1 ), etofenprox (0.3.1 1 ), fenpropathrin (0.3.12), fenvalerate (0.3.13), imiprothrin (0.3.14), lambda-cyhalothrin (0.3.15), permethrin (0.3.16), prallethrin (0.3.17), pyrethrin I and II (0.3.18), resmethrin (0.3.19), silafluofen (O.3.20), tau-fluvalinate (0.3.21 ), tefluthrin (0.3.22), tetramethrin (0.3.23), tralomethrin (0.3.24), transfluthrin (0.3.25), profluthrin (0.3.26), dimefluthrin (0.3.27);

insect growth regulators: a) chitin synthesis inhibitors: benzoylureas:

chlorfluazuron (0.4.1 ), cyramazin (0.4.2), diflubenzuron (0.4.3), flucycloxuron (0.4.4), flufenoxuron (0.4.5), hexaflumuron (0.4.6), lufenuron (0.4.7), novaluron

(0.4.8), teflubenzuron (0.4.9), triflumuron (0.4.10); buprofezin (0.4.1 1 ), diofenolan (0.4.12), hexythiazox (0.4.13), etoxazole (0.4.14), clofentazine (0.4.15); b) ecdysone antagonists: halofenozide (0.4.16), methoxyfenozide (0.4.17), tebufenozide (0.4.18), azadirachtin (0.4.19); c) juvenoids: pyriproxyfen (O.4.20), methoprene (0.4.21 ), fenoxycarb (0.4.22); d) lipid biosynthesis inhibitors: spirodiclofen (0.4.23), spiromesifen (0.4.24), spirotetramat (0.4.24); nicotinic receptor agonists/antagonists compounds: clothianidin (0.5.1 ), dinotefuran (0.5.2), flupyradifurone (0.5.3), imidacloprid (0.5.4), thiamethoxam (0.5.5), nitenpyram (0.5.6), acetamiprid (0.5.7), thiacloprid (0.5.8), 1 -2-chloro- thiazol-5-ylmethyl)-2-nitrimino-3,5-dimethyl-[1 ,3,5]triazinane (0.5.9);

GABA antagonist compounds: endosulfan (0.6.19, ethiprole (0.6.2), fipronil (0.6.3), vaniliprole (0.6.4), pyrafluprole (0.6.5), pyriprole (0.6.6), 5-amino-1 -(2,6- dichloro-4-methyl-phenyl)-4-sulfinamoyl-1 H-pyrazole-3-carbothioic acid amide (0.6.7);

macrocyclic lactone insecticides: abamectin (0.7.1 ), emamectin (0.7.2), milbemectin (0.7.3), lepimectin (0.7.4), spinosad (0.7.5), spinetoram (0.7.6); mitochondrial electron transport inhibitor (METI) I acaricides: fenazaquin (0.8.1 ), pyridaben (0.8.2), tebufenpyrad (0.8.3), tolfenpyrad (0.8.4), flufenerim (0.8.5); METI II and III compounds: acequinocyl (0.9.1 ), fluacyprim (0.9.2),

hydramethylnon (0.9.3);

Uncouplers: chlorfenapyr (0.10.1 );

oxidative phosphorylation inhibitors: cyhexatin (0.1 1.1 ), diafenthiuron (0.1 1 .2), fenbutatin oxide (0.1 1 .3), propargite (0.1 1 .4);

moulting disruptor compounds: cryomazine (0.12.1 );

mixed function oxidase inhibitors: piperonyl butoxide (0.13.1 );

sodium channel blockers: indoxacarb (0.14.1 ), metaflumizone (0.14.2);

ryanodine receptor inhibitors: chlorantraniliprole (0.15.1 ), cyantraniliprole

(0.15.2), flubendiamide (0.15.3), N-[4,6-dichloro-2-[(diethyl-lambda-4- sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyr- azole-3-carboxamide (0.15.4); N-[4-chloro-2-[(diethyl-lambda-4- sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(triflu- oromethyl)pyrazole-3-carboxamide (0.15.5); N-[4-chloro-2-[(di-2-propyl-lambda-

4- sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5- (trifluoromethyl)pyrazole-3-carboxamide (0.15.6); N-[4,6-dichloro-2-[(di-2-propyl- lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-

5- (trifluoromethyl)pyrazole-3-carboxamide (0.15.7); N-[4,6-dichloro-2-[(diethyl- lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5- (difluoromethyl)pyrazole-3-carboxamide (0.15.8); N-[4,6-dibromo-2-[(di-2-propyl- lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5- (trifluoromethyl)pyrazole-3-carboxamide (0.15.9); N-[4-chloro-2-[(di-2-propyl- lambda-4-sulfanylidene)carbamoyl]-6-cyano-phenyl]-2-(3-chloro-2-pyridyl)-5- (trifluoromethyl)pyrazole-3-carboxamide (0.15.10); N-[4,6-dibromo-2-[(diethyl- lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(tri- fluoromethyl)pyrazole-3-carboxamide (0.15.1 1 );

others: benclothiaz (0.16.1 ), bifenazate (0.16.2), artap (0.16.3), flonicamid (0.16.4), pyridalyl (0.16.5), pymetrozine (0.16.6), sulfur (0.16.7), thiocyclam (0.16.8), cyenopyrafen (0.16.9), flupyrazofos (O.16.10), cyflumetofen (0.16.1 1 ), amidoflumet (0.16.12), imicyafos (0.16.13), bistrifluron (0.16.14),

pyrifluquinazon (0.16.15) and 1 ,1 '-[(3S,4R,4aR,6S,6aS,12R,12aS,12bS)-4-[[(2- cyclopropylacetyl)oxy]methyl]-1 ,3,4,4a,5,6,6a,12,12a,12b-decahydro-12-hydroxy- 4,6a, 12b-trimethyl-1 1 -oxo-9-(3-pyridinyl)-2H , 1 1 H-naphtho[2, 1 -b]pyrano[3,4- e]pyran-3,6-diyl] cyclopropaneacetic acid ester (0.16.16).

The present invention furthermore relates to agrochemical compositions comprising a mixture of at least one compound I (component 1 ) and at least one further active substance useful for plant protection, e. g. selected from the groups A) to O) (component 2), in particular one further fungicide, e. g. one or more fungicide from the groups A) to K), as described above, and if desired one suitable solvent or solid carrier. Those mixtures are of particular interest, since many of them at the same application rate show higher efficiencies against harmful fungi. Furthermore, combating harmful fungi with a mixture of compounds I and at least one fungicide from groups A) to L), as described above, is more efficient than combating those fungi with individual compounds I or individual fungicides from groups A) to L). By applying compounds I together with at least one active substance from groups A) to O) a synergistic effect can be obtained, i.e. more then simple addition of the individual effects is obtained (synergistic mixtures).

This can be obtained by applying the compounds I and at least one further active substance simultaneously, either jointly (e. g. as tank-mix) or seperately, or in succession, wherein the time interval between the individual applications is selected to ensure that the active substance applied first still occurs at the site of action in a sufficient amount at the time of application of the further active substance(s). The order of application is not essential for working of the present invention.

When applying compounds I and a pesticide II sequentially the time between both applications may vary e.g. between 2 hours to 7 days. Also a broader range is possible ranging from 0.25 hour to 30 days, preferably from 0.5 hour to 14 days, particularly from 1 hour to 7 days or from 1 .5 hours to 5 days, even more preferred from 2 hours to 1 day. In case of a mixture comprising a pesticide II selected from group L), it is preferred that the pesticide II is applied as last treatment.

According to the invention, the solid material (dry matter) of the biopesticides (with the exception of oils such as Neem oil, Tagetes oil, etc.) are considered as active components (e.g. to be obtained after drying or evaporation of the extraction medium or the suspension medium in case of liquid formulations of the microbial pesticides). In accordance with the present invention, the weight ratios and percentages used herein for a biological extract such as Quillay extract are based on the total weight of the dry content (solid material) of the respective extract(s).

The total weight ratios of compositions comprising at least one microbial pesticide in the form of viable microbial cells including dormant forms, can be determined using the amount of CFU of the respective microorganism to calclulate the total weight of the respective active component with the following equation that 1 x 10⁹ CFU equals one gram of total weight of the respective active component. Colony forming unit is measure of viable microbial cells, in particular fungal and bacterial cells. In addition, here "CFU" may also be understood as the number of (juvenile) individual nematodes in case of (entomopathogenic) nematode biopesticides, such as Steinernema feltiae.

In binary mixtures, i.e. compositions according to the invention comprising one compound I (component 1 ) and one further active substance (component 2), e. g. one active substance from groups A) to O), the weight ratio of component 1 and component 2 generally depends from the properties of the active substances used, usually it is in the range of from 1 :100 to 100:1 , regularly in the range of from 1 :50 to 50:1 , preferably in the range of from 1 :20 to 20:1 , more preferably in the range of from 1 :10 to 10:1 and even more preferably in the range of from 1 :3 to 3:1 and in particular in the range of from 1 :2 to 2:1 .

According to a further embodiments of the binary mixtures and compositions, the weight ratio of the component 1 ) and the component 2) usually is in the range of from 1000:1 to 1 :1 , often in the range of from 100:1 to 1 :1 , regularly in the range of from 50:1 to 1 :1 , preferably in the range of from 20:1 to 1 :1 , more preferably in the range of from 10:1 to 1 :1 , even more preferably in the range of from 4:1 to 1 :1 and in particular in the range of from 2:1 to 1 :1.

According to a further embodiments of the binary mixtures and compositions, the weight ratio of the component 1 ) and the component 2) usually is in the range of from 1 :1 to 1 :1000, often in the range of from 1 :1 to 1 :100, regularly in the range of from 1 :1 to 1 :50, preferably in the range of from 1 :1 to 1 :20, more preferably in the range of from 1 :1 to 1 :10, even more preferably in the range of from 1 :1 to 1 :4 and in particular in the range of from 1 :1 to 1 :2.

In ternary mixtures, i.e. compositions according to the invention comprising one compound I (component 1 ) and a first further active substance (component 2) and a second further active substance (component 3), e. g. two active substances from groups A) to O), the weight ratio of component 1 and component 2 depends from the properties of the active substances used, usually it is in the range of from 1 :100 to 100:1 , regularly in the range of from 1 :50 to 50:1 , preferably in the range of from 1 :20 to 20:1 , more preferably in the range of from 1 :10 to 10:1 and in particular in the range of from 1 :4 to 4:1 , and the weight ratio of component 1 ) and component 3) usually it is in the range of from 1 :100 to 100:1 , regularly in the range of from 1 :50 to 50:1 , preferably in the range of from 1 :20 to 20:1 , more preferably in the range of from 1 :10 to 10:1 and in particular in the range of from 1 :4 to 4:1 .

Any further active components are, if desired, added in a ratio of from 20:1 to 1 :20 to the component 1 ).

These ratios are also suitable for inventive mixtures applied by seed treatment.

Preference is also given to mixtures comprising a compound I (component 1 ) and at least one active substance selected from group A) (component 2) and particularly selected from azoxystrobin (A.1.1 ), dimoxystrobin (A.1 .4), fluoxastrobin (A.1 .8), kresoxim-methyl (A.1 .9), orysastrobin (A.1 .12), picoxystrobin (A.1 .13), pyraclostrobin (A.1.14), trifloxystrobin (A.1 .17), pyribencarb (A.1 .19), famoxadone (A.1.21 ), cyazofamid (A.2.1 ), amisulbrom (A.2.2), benzovindiflupyr (A.3.2), bixafen (A.3.3), boscalid (A.3.4), fluopyram (A.3.7), flutolanil (A.3.8), fluxapyroxad (A.3.9), isopyrazam (A.3.12), oxycarboxin (A.3.14), penflufen (A.3.14), penthiopyrad (A.3.15), sedaxane (A.3.16), N-(4'-trifluoromethylthiobiphenyl-2-yl)-3-difluoromethyl-1 -methyl-1 H-pyrazole- 4-carboxamide (A.3.19), N-(2-(1 ,3,3-trimethyl-butyl)-phenyl)-1 ,3-dimethyl-5-fluoro-1 H- pyrazole-4-carboxamide (A.3.20), 3-(difluoromethyl)-1 -methyl-N-(1 ,1 ,3-trimethylindan- 4-yl)pyrazole-4-carboxamide (A.3.21 ), 3-(trifluoromethyl)-1 -methyl-N-(1 ,1 ,3-trimethyl- indan-4-yl)pyrazole-4-carboxamide (A.3.22), 1 ,3-dimethyl-N-(1 ,1 ,3-trimethylindan-4- yl)pyrazole-4-carboxamide (A.3.23), 3-(trifluoromethyl)-1 ,5-dimethyl-N-(1 ,1 ,3- trimethylindan-4-yl)pyrazole-4-carboxamide (A.3.24), 1 ,3,5-trimethyl-N-(1 ,1 ,3- trimethylindan-4-yl)pyrazole-4-carboxamide (A.3.25), N-(7-fluoro-1 ,1 ,3-trimethyl-indan- 4-yl)-1 ,3-dimethyl-pyrazole-4-carboxamide (A.3.26), N-[2-(2,4-dichlorophenyl)-2- methoxy-1 -methyl-ethyl]-3-(difluoromethyl)-1 -methyl-pyrazole-4-carboxamide (A.3.27), dinocap (A.4.5), fluazinam (A.4.6); fentin-acetate (A.4.8), fentin chloride (A.4.9) and ametoctradin (A.4.1 1 ).

Preference is given to mixtures comprising a compound of formula I (component 1 ) and at least one active substance selected from group B) (component 2) and particularly selected from cyproconazole (B.1.4), difenoconazole (B.1 .5), diniconazole (B.1 .6), epoxiconazole (B.1 .8), fluquinconazole (B.1.10), flusilazole (B.1 .1 1 ), flutriafol (B.1.12), metconazole (B.1 .17), myclobutanil (B.1.18), penconazole (B.1.21 ), propiconazole (B.1.22), prothioconazole (B.1.23), tebuconazole (B.1 .25), tetraconazole (B.1.26), triadimefon (B.1 .27), triadimenol (B.1.28), triticonazole (B.1.29), uniconazole (B.1.30), 1 -[re/-(2S;3R)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)-oxiranylmethyl]-5-thiocyanato- 1 H-[1 ,2,4]triazolo (B.1.31 ), 2-[re/-(2S;3R)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)-oxi- ranylmethyl]-2H-[1 ,2,4]triazole-3-thiol (B.1 .32), 2-[2-chloro-4-(4-chlorophenoxy)phenyl]- 1 -(1 ,2,4-triazol-1 -yl)pentan-2-ol (B.1 .33), 1 -[4-(4-chlorophenoxy)-2-(trifluoro- methyl)phenyl]-1 -cyclopropyl-2-(1 ,2,4-triazol-1 -yl)ethanol (B.1 .34), 2-[4-(4-chloro- phenoxy)-2-(trifluoromethyl)phenyl]-1 -(1 ,2,4-triazol-1 -yl)butan-2-ol (B.1.35), 2-[2-chloro- 4-(4-chlorophenoxy)phenyl]-1 -(1 ,2,4-triazol-1 -yl)butan-2-ol (B.1 .36), 2-[4-(4-chloro- phenoxy)-2-(trifluoromethyl)phenyl]-3-methyl-1 -(1 ,2,4-triazol-1 -yl)butan-2-ol (B.1 .37), 2- [4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1 -(1 ,2,4-triazol-1 -yl)propan-2-ol

(B.1.38), 2-[2-chloro-4-(4-chlorophenoxy)phenyl]-3-methyl-1 -(1 ,2,4-triazol-1 -yl)butan-2- ol (B.1 .39), 2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1 -(1 ,2,4-triazol-1 - yl)pentan-2-ol (B.1 .40), 2-[4-(4-fluorophenoxy)-2-(trifluoromethyl)phenyl]-1 -(1 ,2,4- triazol-1 -yl)propan-2-ol (B.1.41 ), imazalil (B.1.42), prochloraz (B.1.44), fenarimol (B.1.46), triforine (B.1 .49), [3-(4-chloro-2-fluoro-phenyl)-5-(2,4-difluorophenyl)isoxazol- 4-yl]-(3-pyridyl)methanol (B.1.50), dodemorph (B.2.2), fenpropimorph (B.2.4), tridemorph (B.2.5), fenpropidin (B.2.6), piperalin (B.2.7), spiroxamine (B.2.8) and fenhexamid (B.3.1 ).

Preference is given to mixtures comprising a compound of formula I (component 1 ) and at least one active substance selected from group C) (component 2) and particularly selected from metalaxyl (C.1 .4), metalaxyl-M (mefenoxam, C.1 .5), ofurace (C.1 .6) and bupirimate (C.2.4).

Preference is given to mixtures comprising a compound of formula I (component 1 ) and at least one active substance selected from group D) (component 2) and particularly selected from benomyl (D1 .1 ), carbendazim (D1 .2), thiabendazole (D1 .4), thiophanate- methyl (D1 .5),

ethaboxam (D2.2), fluopicolide (D2.4), zoxamide (D2.5), metrafenone (D2.6), pyriofenone (D2.7). Preference is also given to mixtures comprising a compound I (component 1 ) and at least one active substance selected from group E) (component 2) and particularly selected from cyprodinil (E.1.1 ), mepanipyrim (E.1.2), pyrimethanil (E.1 .3).

Preference is also given to mixtures comprising a compound I (component 1 ) and at least one active substance selected from group F) (component 2) and particularly selected from iprodione (F.1 .2), vinclozolin (F.1.4), fenpiclonil (F.1 .5), fludioxonil (F.1 .6) and quinoxyfen (F.2.1 ).

Preference is also given to mixtures comprising a compound I (component 1 ) and at least one active substance selected from group G) (component 2) and particularly selected from dimethomorph (G.3.1 ), flumorph (G.3.2), mandipropamid (G.3.3), pyrimorph (G.3.4), benthiavalicarb (G.3.5), iprovalicarb (G.3.6), propamocarb (G.4.1 ), oxathiapiprolin (G.5.1 ).

Preference is also given to mixtures comprising a compound I (component 1 ) and at least one active substance selected from group H) (component 2) and particularly selected from copper acetate (H.1.2), copper hydroxide (H.1 .3), copper oxychloride (H.1 .4), basic copper sulfate (H.1.5), sulfur (H.1 .6), mancozeb (H.2.2), metiram (H.2.5), thiram (H.2.7), chlorothalonil (H.3.2), captafol (H.3.3), captan (H.3.4), folpet (H.3.5), dichlofluanid (H.3.6), N-(4-chloro-2-nitro-phenyl)-N-ethyl-4-methyl-benzenesulfonamide (H.3.12), dodine (H.4.2), iminoctadine (H.4.6), dithianon (H.4.9) and 2,6-dimethyl- 1 H,5H-[1 ,4]dithiino[2,3-c:5,6-c']dipyrrole-1 ,3,5,7(2H,6H)-tetraone (H.4.10).

Preference is also given to mixtures comprising a compound I (component 1 ) and at least one active substance selected from group I) (component 2) and particularly selected from carpropamid (1.2.3), and fenoxanil (1.2.5).

Preference is also given to mixtures comprising a compound I (component 1 ) and at least one active substance selected from group J) (component 2) and particularly selected from acibenzolar-S-methyl (J.1.1 ), probenazole (J.1.2), isotianil (J.1.3), tiadinil (J.1.4), prohexadione-calcium (J.1 .5), fosetyl (J.1 .6), fosetyl-aluminum (J.1 .7), phosphorous acid and its salts (J.1.8), potassium or sodium bicarbonate (J.1 .9).

Preference is also given to mixtures comprising a compound I (component 1 ) and at least one active substance selected from group K) (component 2) and particularly selected from cymoxanil (K.1.4), dazomet (K.1 .5), difenzoquat (K.1.8), flumetover (K.1.12), flusulfamide (K.1.13), flutianil (K.1.14), methasulfocarb (K.1.15),

oxathiapiprolin (K.1 .19) and proquinazid (K.1.22).

The biopesticides from group L) of pesticides II, their preparation and their pesticidal activity e.g. against harmful fungi or insects are known (e-Pesticide Manual V 5.2 (ISBN 978 1 901396 85 0) (2008-201 1 ); http://www.epa.gov/opp00001/biopesticides/, see product lists therein; http://www.omri.org/omri-lists, see lists therein; Bio-Pesticides Database BPDB http://sitem.herts.ac.uk/aeru/bpdb/, see A to Z link therein).

The biopesticides from group L1 ) and/or L2) may also have insecticidal, acaricidal, molluscidal, pheromone, nematicidal, plant stress reducing, plant growth regulator, plant growth promoting and/or yield enhancing activity. The biopesticides from group L3) and/or L4) may also have fungicidal, bactericidal, viricidal, plant defense activator, plant stress reducing, plant growth regulator, plant growth promoting and/or yield enhancing activity. The biopesticides from group L5) and/or L6) may also have fungicidal, bactericidal, viricidal, plant defense activator, insecticidal, acaricidal, molluscidal, pheromone and/or nematicidal activity.

Many of these biopesticides are registered and/or are commercially available:

aluminium silicate (Screen™ Duo from Certis LLC, USA), Agrobacterium radiobacter K1026 (e.g. NoGall® from Becker Underwood Pty Ltd., Australia), A. radiobacter K84 (Nature 280, 697-699, 1979; e.g. GallTroll® from AG Biochem, Inc., C, USA),

Ampelomyces quisqualis M-10 (e.g. AQ 10® from Intrachem Bio GmbH & Co. KG,

Germany), Ascophyllum nodosum (Norwegian kelp, Brown kelp) extract or filtrate (e.g. ORKA GOLD from Becker Underwood, South Africa; or Goemar® from Laboratoires Goemar, France), Aspergillus flavus NRRL 21882 isolated from a peanut in Georgia in 1991 by the USDA, National Peanut Research Laboratory (e.g. in Afla-Guard® from Syngenta, CH), mixtures of Aureobasidium pullulans DSM14940 and DSM 14941 (e.g. blastospores in Blossom Protect® from bio-ferm GmbH, Germany), Azospirillum amazonense BR 1 1 140 (SpY2^T) (Proc. 9^th Int. and 1 ^st Latin American PGPR meeting, Quimara, Medellin, Colombia 2012, p. 60, ISBN 978-958-46-0908-3), A. brasilense AZ39 (Eur. J. Soil Biol 45(1 ), 28-35, 2009), A. brasilense XOH (e.g. AZOS from Xtreme Gardening, USA or RTI Reforestation Technologies International; USA), A. brasilense BR 1 1002 (Proc. 9^th Int. and 1 ^st Latin American PGPR meeting, Quimara, Medellin, Colombia 2012, p. 60, ISBN 978-958-46-0908-3), A. brasilense BR 1 1005 (SP245; e.g. in GELFIX Gramineas from BASF Agricultural Specialties Ltd., Brazil), A. lipoferum BR 1 1646 (Sp31 ) (Proc. 9^th Int. and 1 ^st Latin American PGPR meeting, Quimara, Medellin, Colombia 2012, p. 60), Bacillus amyloliquefaciens FZB42 (e.g. in RhizoVital® 42 from AbiTEP GmbH, Berlin, Germany), B. amyloliquefaciens IN937a (J. Microbiol.

Biotechnol. 17(2), 280-286, 2007; e.g. in BioYield® from Gustafson LLC, TX, USA), B. amyloliquefaciens IT-45 (CNCM I-3800) (e.g. Rhizocell C from ITHEC, France), B. amyloliquefaciens subsp. plantarum MBI600 (NRRL B-50595, deposited at United States Department of Agriculture) (e.g. Integral®, Subtilex® NG from Becker

Underwood, USA), B. cereus CNCM 1-1562 (US 6,406,690), B. firmus CNCM 1-1582 (WO 2009/126473, WO 2009/124707, US 6,406,690; Votivo® from Bayer Crop

Science LP, USA), B. pumilus GB34 (ATCC 700814; e.g. in YieldShield® from

Gustafson LLC, TX, USA), and Bacillus pumilus KFP9F (NRRL B-50754) (e.g. in BAC- UP or FUSION-P from Becker Underwood South Africa), B. pumilus QST 2808 (NRRL B-30087) (e.g. Sonata® and Ballad® Plus from AgraQuest Inc., USA), B. subtilis GB03 (e.g. Kodiak® or BioYield® from Gustafson, Inc., USA; or Companion® from Growth Products, Ltd., White Plains, NY 10603, USA), B. subtilis GB07 (Epic® from Gustafson, Inc., USA), B. subtilis QST-713 (NRRL B-21661 in Rhapsody®, Serenade® MAX and Serenade® ASO from AgraQuest Inc., USA), B. subtilis var. amyloliquefaciens FZB24 (e.g. Taegro® from Novozyme Biologicals, Inc., USA), B. subtilis var. amyloliquefaciens D747 (e.g. Double Nickel 55 from Certis LLC, USA), B. thuringiensis ssp. aizawai ABTS-1857 (e.g. in XenTari® from BioFa AG, Munsingen, Germany), B. t. ssp. aizawai SAN 401 I, ABG-6305 and ABG-6346, Bacillus t. ssp. israelensis AM65-52 (e.g. in VectoBac® from Valent Biosciences, IL, USA), Bacillus thuringiensis ssp. kurstaki SB4 (NRRL B-50753; e.g. Beta Pro® from Becker Underwood, South Africa), B. t. ssp. kurstaki ABTS-351 identical to HD-1 (ATCC SD-1275; e.g. in Dipel® DF from Valent Biosciences, IL, USA), B. t. ssp. kurstaki EG 2348 (e.g. in Lepinox® or Rapax® from CBC (Europe) S.r.l., Italy), B. t. ssp. tenebrionis DSM 2803 (EP 0 585 215 B1 ; identical to NRRL B-15939; Mycogen Corp.), B. t. ssp. tenebrionis NB-125 (DSM 5526; EP 0 585 215 B1 ; also referred to as SAN 418 I or ABG-6479; former production strain of Novo-Nordisk), B. t. ssp. tenebrionis NB-176 (or NB-176-1 ) a gamma-irridated, induced high-yielding mutant of strain NB-125 (DSM 5480; EP 585 215 B1 ; Novodor® from

Valent Biosciences, Switzerland), Beauveria bassiana ATCC 74040 (e.g. in Naturalis® from CBC (Europe) S.r.l., Italy), B. bassiana DSM 12256 (US 200020031495; e.g. BioExpert® SC from Live Sytems Technology S.A., Colombia), B. bassiana GHA (BotaniGard® 22WGP from Laverlam Int. Corp., USA), B. bassiana PPRI 5339

(ARSEF number 5339 in the USDA ARS collection of entomopathogenic fungal cultures; NRRL 50757) (e.g. Broad Band® from Becker Underwood, South Africa), B. brongniartii (e.g. in Melocont® from Agrifutur, Agrianello, Italy, for control of cockchafer; J. Appl. Microbiol. 100(5), 1063-72, 2006), Bradyrhizobium sp. (e.g. Vault® from Becker Underwood, USA), B. japonicum (e.g. VAULT® from Becker Underwood, USA), Candida oleophila 1-182 (NRRL Y-18846; e.g. Aspire® from Ecogen Inc., USA,

Phytoparasitica 23(3), 231 -234, 1995), C. oleophila strain O (NRRL Y-2317; Biological Control 51 , 403-408, 2009),, Candida saitoana (e.g. Biocure® (in mixture with lysozyme) and BioCoat® from Micro Flo Company, USA (BASF SE) and Arysta), Chitosan (e.g. Armour-Zen® from BotriZen Ltd., NZ), Clonostachys rosea f. catenulata, also named Gliocladium catenulatum (e.g. isolate J 1446: Prestop® from Verdera Oy, Finland), Chromobacterium subtsugae PRAA4-1 isolated from soil under an eastern hemlock (Tsuga canadensis) in the Catoctin Mountain region of central Maryland (e.g. in GRANDEVO from Marrone Bio Innovations, USA), Coniothyrium minitans

CON/M/91 -08 (e.g. Contans® WG from Prophyta, Germany), Cryphonectria parasitica (e.g. Endothia parasitica from CNICM, France), Cryptococcus albidus (e.g. YIELD PLUS® from Anchor Bio-Technologies, South Africa), Cryptophlebia leucotreta granulovirus (CrIeGV) (e.g. in CRYPTEX from Adermatt Biocontrol, Switzerland), Cydia pomonella granulovirus (CpGV) V03 (DSM GV-0006; e.g. in MADEX Max from

Andermatt Biocontrol, Switzerland), CpGV V22 (DSM GV-0014; e.g. in MADEX Twin from Adermatt Biocontrol, Switzerland), Delftia acidovorans RAY209 (ATCC PTA-4249; WO 2003/57861 ; e.g. in BIOBOOST from Brett Young, Winnipeg, Canada),

Dilophosphora alopecuri (Twist Fungus from Becker Underwood, Australia), Ecklonia maxima (kelp) extract (e.g. KELPAK SL from Kelp Products Ltd, South Africa), formononetin (e.g. in MYCONATE from Plant Health Care pic, U.K.), Fusarium oxysporum (e.g. BIOFOX® from S.I.A.P.A., Italy, FUSACLEAN® from Natural Plant Protection, France), Glomus intraradices (e.g. MYC 4000 from ITHEC, France), Glomus intraradices RTI-801 (e.g. MYKOS from Xtreme Gardening, USA or RTI Reforestation Technologies International; USA), grapefruit seeds and pulp extract (e.g. BC-1000 from Chemie S.A., Chile), harpin (alpha-beta) protein (e.g. MESSENGER or HARP-N-Tek from Plant Health Care pic, U.K.; Science 257, 1-132, 1992),

Heterorhabditis bacteriophaga (e.g. Nemasys® G from Becker Underwood Ltd., UK), Isaria fumosorosea Apopka-97 (ATCC 20874) (PFR-97™ from Certis LLC, USA), cis- jasmone (US 8,221 ,736), laminarin (e.g. in VACCI PLANT from Laboratoires Goemar, St. Malo, France or Stahler SA, Switzerland), Lecanicillium longisporum KV42 and KV71 (e.g. VERTALEC® from Koppert BV, Netherlands), L. muscarium KV01 (formerly Verticillium lecanii) (e.g. MYCOTAL from Koppert BV, Netherlands), Lysobacter antibioticus 13-1 (Biological Control 45, 288-296, 2008), L. antibioticus HS124 (Curr. Microbiol. 59(6), 608-615, 2009), L. enzymogenes 3.1 T8 (Microbiol. Res. 158, 107-1 15; Biological Control 31 (2), 145-154, 2004), Metarhizium anisopliae var. acridum IMI 330189 (isolated from Ornithacris cavroisi in Niger; also NRRL 50758) (e.g. GREEN MUSCLE® from Becker Underwood, South Africa), M. a. var. acridum FI-985 (e.g. GREEN GUARD® SC from Becker Underwood Pty Ltd, Australia), M. anisopliae Fl- 1045 (e.g. BIOCANE® from Becker Underwood Pty Ltd, Australia), M. anisopliae F52 (DSM 3884, ATCC 90448; e.g. MET52® Novozymes Biologicals BioAg Group,

Canada), M. anisopliae ICIPE 69 (e.g. METATHRIPOL from ICIPE, Nairobe, Kenya), Metschnikowia fructicola (NRRL Y-30752; e.g. SHEMER® from Agrogreen, Israel, now distributed by Bayer CropSciences, Germany; US 6,994,849), Microdochium dimerum (e.g. ANTIBOT® from Agrauxine, France), Microsphaeropsis ochracea P130A (ATCC 74412 isolated from apple leaves from an abandoned orchard, St-Joseph-du-Lac, Quebec, Canada in 1993; Mycologia 94(2), 297-301 , 2002), Muscodor albus QST 20799 originally isolated from the bark of a cinnamon tree in Honduras (e.g. in development products Muscudor™ or QRD300 from AgraQuest, USA), Neem oil (e.g. TRILOGY®, TRIACT® 70 EC from Certis LLC, USA), Nomuraea rileyi strains

SA86101 , GU87401 , SR86151 , CG128 and VA9101 , Paecilomyces fumosoroseus FE 9901 (e.g. NO FLY™ from Natural Industries, Inc., USA), P. Iilacinus 251 (e.g. in BioAct®/MeloCon® from Prophyta, Germany; Crop Protection 27, 352-361 , 2008; originally isolated from infected nematode eggs in the Philippines), P. Iilacinus DSM 15169 (e.g. NEMATA® SC from Live Systems Technology S.A., Colombia), P. Iilacinus BCP2 (NRRL 50756; e.g. PL GOLD from Becker Underwood BioAg SA Ltd, South Africa), mixture of Paenibacillus alvei NAS6G6 (NRRL B-50755), Pantoea vagans (formerly agglomerans) C9-1 (originally isolated in 1994 from apple stem tissue;

BlightBan C9-1® from NuFrams America Inc., USA, for control of fire blight in apple; J. Bacteriol. 192(24) 6486-6487, 2010), Pasteuria spp. ATCC PTA-9643 (WO

2010/085795), Pasteuria spp. ATCC SD-5832 (WO 2012/064527), P. nishizawae (WO 2010/80169), P. penetrans (US 5,248,500), P. ramose (WO 2010/80619), P. thornea (WO 2010/80169), P. usgae (WO 2010/80169), Penicillium bilaiae (e.g. Jump Start® from Novozymes Biologicals BioAg Group, Canada, originally isolated from soil in southern Alberta; Fertilizer Res. 39, 97-103, 1994), Phlebiopsis gigantea (e.g.

RotStop® from Verdera Oy, Finland), Pichia anomala WRL-076 (NRRL Y-30842; US 8,206,972), potassium bicarbonate (e.g. Amicarb® fromm Stahler SA, Switzerland), potassium silicate (e.g. Sil-MATRIX™ from Certis LLC, USA), Pseudozyma flocculosa PF-A22 UL (e.g. Sporodex® from Plant Products Co. Ltd., Canada), Pseudomonas sp. DSM 13134 (WO 2001/40441 , e.g. in PRORADIX from Sourcon Padena GmbH & Co. KG, Hechinger Str. 262, 72072 Tubingen, Germany), P. chloraphis MA 342 (e.g. in CERALL or CEDEMON from BioAgri AB, Uppsala, Sweden), P. fluorescens CL 145A (e.g. in ZEQUANOX from Marrone Biolnnovations, Davis, CA, USA; J. Invertebr.

Pathol. 1 13(1 ):104-14, 2013), Pythium oligandrum DV 74 (ATCC 38472; e.g.

POLYVERSUM® from Remeslo SSRO, Biopreparaty, Czech Rep. and GOWAN, USA; US 2013/0035230), Reynoutria sachlinensis extract (e.g. REGALIA® SC from Marrone Biolnnovations, Davis, CA, USA), Rhizobium leguminosarum bv. phaseoli (e.g. RHIZO- STICK from Becker Underwood, USA), R. I. trifolii RP1 13-7 (e.g. DORMAL from Becker Underwood, USA; Appl. Environ. Microbiol. 44(5), 1096-1 101 ), R. I. bv. viciae

P1 NP3Cst (also referred to as 1435; New Phytol 179(1 ), 224-235, 2008; e.g. in

NODULATOR PL Peat Granule from Becker Underwood, USA; or in NODULATOR XL PL bfrom Becker Underwood, Canada), R. I. bv. viciae SU303 (e.g. NODULAID Group E from Becker Underwood, Australia), R. I. bv. viciae WSM1455 (e.g. NODULAID

Group F from Becker Underwood, Australia), R. tropici SEMIA 4080 (identical to PRF 81 ; Soil Biology & Biochemistry 39, 867-876, 2007), Sinorhizobium meliloti MSDJ0848 (INRA, France) also referred to as strain 201 1 or RCR201 1 (Mol Gen Genomics (2004) 272: 1-17; e.g. DORMAL ALFALFA from Becker Underwood, USA; NITRAGIN® Gold from Novozymes Biologicals BioAg Group, Canada), Sphaerodes mycoparasitica IDAC 301008-01 (WO 201 1/022809), Steinernema carpocapsae (e.g. MILLENIUM® from Becker Underwood Ltd., UK), S. feltiae (NEMASHIELD® from BioWorks, Inc., USA; NEMASYS® from Becker Underwood Ltd., UK), S. kraussei L137 (N E MAS YS® L from Becker Underwood Ltd., UK), Streptomyces griseoviridis K61 (e.g. MYCOSTOP® from Verdera Oy, Espoo, Finland; Crop Protection 25, 468-475, 2006), S. lydicus WYEC 108 (e.g. Actinovate® from Natural Industries, Inc., USA, US 5,403,584), S. violaceusniger YCED-9 (e.g. DT-9® from Natural Industries, Inc., USA, US 5,968,503), Talaromyces flavus V1 17b (e.g. PROTUS® from Prophyta, Germany), Trichoderma asperellum SKT-1 (e.g. ECO-HOPE® from Kumiai Chemical Industry Co., Ltd., Japan), T.

asperellum ICC 012 (e.g. in TENET WP, REMDIER WP, BIOTEN WP from Isagro NC, USA, BIO-TAM from AgraQuest, USA), T. atroviride LC52 (e.g. SENTINEL® from Agrimm Technologies Ltd, NZ), T. atroviride CNCM 1-1237 (e.g. in Esquive WG from Agrauxine S.A., France, e.g. against pruning wound diseases on vine and plant root pathogens), T. fertile JM41 R (NRRL 50759; e.g. RICHPLUS™ from Becker Underwood Bio Ag SA Ltd, South Africa), T. gamsii ICC 080 (e.g. in TENET WP, REMDIER WP, BIOTEN WP from Isagro NC, USA, BIO-TAM from AgraQuest, USA), T. harzianum T- 22 (e.g. PLANTSHIELD® der Firma BioWorks Inc., USA), T. harzianum TH 35 (e.g. ROOT PRO® from Mycontrol Ltd., Israel), T. harzianum T-39 (e.g. TRICHODEX® and TRICHODERMA 2000® from Mycontrol Ltd., Israel and Makhteshim Ltd., Israel), T. harzianum and T. viride (e.g. TRICHOPEL from Agrimm Technologies Ltd, NZ), T. harzianum ICC012 and T. viride ICC080 (e.g. REMEDIER® WP from Isagro Ricerca, Italy), T. polysporum and T. harzianum (e.g. BINAB® from BINAB Bio-Innovation AB, Sweden), T. stromaticum (e.g. TRICOVAB® from C.E.P.L.A.C., Brazil), T. virens GL-21 (also named Gliocladium virens) (e.g. SOILGARD® from Certis LLC, USA), T. viride (e.g. TRIECO® from Ecosense Labs. (India) Pvt. Ltd., Indien, BIO-CURE® F from T. Stanes & Co. Ltd., Indien), T. viride TV1 (e.g. T. viride TV1 from Agribiotec srl, Italy) and Ulocladium oudemansii HRU3 (e.g. in BOTRY-ZEN® from Botry-Zen Ltd, NZ). Strains can be sourced from genetic resource and deposition centers: American Type Culture Collection, 10801 University Blvd., Manassas, VA 201 10-2209, USA (strains with ATCC prefic); CABI Europe - International Mycological Institute, Bakeham Lane, Egham, Surrey, TW20 9TYNRRL, UK (strains with prefices CABI and IMI);

Centraalbureau voor Schimmelcultures, Fungal Biodiversity Centre, Uppsalaan 8, PO Box 85167, 3508 AD Utrecht, Netherlands (strains with prefic CBS); Division of Plant Industry, CSIRO, Canberra, Australia (strains with prefix CC); Collection Nationale de Cultures de Microorganismes, Institut Pasteur, 25 rue du Docteur Roux, F-75724 PARIS Cedex 15 (strains with prefix CNCM); Leibniz-lnstitut DSMZ-Deutsche

Sammlung von Mikroorganismen und Zellkulturen GmbH, Inhoffenst^e 7 B, 38124 Braunschweig, Germany (strains with prefix DSM); International Depositary Authority of Canada Collection, Canada (strains with prefix IDAC); Interntional Collection of Micro- orgniasms from Plants, Landcare Research, Private Bag 92170, Auckland Mail Centre, Auckland 1 142, New Zealand (strans with prefix ICMP); IITA, PMB 5320, Ibadan, Nigeria (straisn with prefix IITA); The National Collections of Industrial and Marine Bacteria Ltd., Torry Research Station, P.O. Box 31 , 135 Abbey Road, Aberdeen, AB9 8DG, Scotland (strains with prefix NCIMB); ARS Culture Collection of the National Center for Agricultural Utilization Research, Agricultural Research Service, U.S.

Department of Agriculture, 1815 North University Street, Peoria, Illinois 61604, USA (strains with prefix NRRL); Department of Scientific and Industrial Research Culture Collection, Applied Biochemistry Division, Palmerston North, New Zealand (strains with prefix NZP); FEPAGRO-Fundagao Estadual de Pesquisa Agropecuaria, Rua

Gongalves Dias, 570, Bairro Menino Deus, Porto Alegre/RS, Brazil (strains with prefix SEMIA); SARDI, Adelaide, South Australia (strains with prefix SRDI); U.S. Department of Agriculture, Agricultural Research Service, Soybean and Alfalfa Research

Laboratory, BARC-West, 10300 Baltimore Boulevard, Building 01 1 , Room 19-9, Beltsville, MD 20705, USA (strains with prefix USDA: Beltsville Rhizobium Culture Collection Catalog March 1987 USDA-ARS ARS-30:

http://pdf.usaid.gov/pdf_docs/PNAAW891.pdf); and Murdoch University, Perth, Western Australia (strains with prefix WSM). Further strains may be found at the Global catalogue of Microorganisms: http://gcm.wfcc.info/ and

http://www.landcareresearch.co.nz/resources/collections/icmp and further references to strain collections and their prefixes at http://refs.wdcm.org/collections.htm.

Bacillus amyloliquefaciens subsp. plantarum MBI600 (NRRL B-50595) is deposited under accession number NRRL B-50595 with the strain designation Bacillus subtilis 1430 (and identical to NCIMB 1237). Recently, MBI 600 has been re-classified as Bacillus amyloliquefaciens subsp. plantarum based on polyphasic testing which combines classical microbiological methods relying on a mixture of traditional tools (such as culture-based methods) and molecular tools (such as genotyping and fatty acids analysis). Thus, Bacillus subtilis MBI600 (or MBI 600 or MBI-600) is identical to Bacillus amyloliquefaciens subsp. plantarum MBI600, formerly Bacillus subtilis MBI600. Bacillus amyloliquefaciens MBI600 is known as plant growth-promoting rice seed treatment from Int. J. Microbiol. Res. 3(2) (201 1 ), 120-130 and further described e.g. in US 2012/0149571 A1 . This strain MBI600 is e.g. commercially available as liquid formulation product INTEGRAL® (Becker-Underwood Inc., USA).

Bacillus subtilis strain FB17 was originally isolated from red beet roots in North America (System Appl. Microbiol 27 (2004) 372-379). This B. subtilis strain promotes plant health (US 2010/0260735 A1 ; WO 201 1/109395 A2). B. subtilis FB17 has also been deposited at ATCC under number PTA-1 1857 on April 26, 201 1. Bacillus subtilis strain FB17 may be referred elsewhere to as UD1022 or UD10-22.

Bacillus amyloliquefaciens AP-136 (NRRL B-50614), B. amyloliquefaciens AP-188 (NRRL B-50615), B. amyloliquefaciens AP-218 (NRRL B-50618), B. amyloliquefaciens AP-219 (NRRL B-50619), B. amyloliquefaciens AP-295 (NRRL B-50620), B. japonicum SEMIA 5079 (e.g. Gelfix 5 or Adhere 60 from Nitral Urbana Laoboratories, Brazil, a

BASF Company), B. japonicum SEMIA 5080 (e.g. GELFIX 5 or ADHERE 60 from Nitral Urbana Laoboratories, Brazil, a BASF Company), B. mojavensis AP-209 (NRRL B- 50616), B. solisalsi AP-217 (NRRL B-50617), B. pumilus strain INR-7 (otherwise referred to as BU-F22 (NRRL B-50153) and BU-F33 (NRRL B-50185)), B. simplex ABU 288 (NRRL B-50340) and B. amyloliquefaciens subsp. plantarum MBI600 (NRRL B- 50595) have been mentioned i.a. in US patent appl. 20120149571 , US 8,445,255, WO 2012/079073. Bradyrhizobium japonicum USDA 3 is known from US patent 7,262,151. Jasmonic acid or salts (jasmonates) or derivatives include without limitation potassium jasmonate, sodium jasmonate, lithium jasmonate, ammonium jasmonate, dimethyl- ammonium jasmonate, isopropylammonium jasmonate, diolammonium jasmonate, diethtriethanolammonium jasmonate, jasmonic acid methyl ester, jasmonic acid amide, jasmonic acid methylamide, jasmonic acid-L-amino acid (amide-linked) conjugates (e.g., conjugates with L-isoleucine, L-valine, L-leucine, or L-phenylalanine), 12-oxo- phytodienoic acid, coronatine, coronafacoyl-L-serine, coronafacoyl-L-threonine, methyl esters of 1 -oxo-indanoyl-isoleucine, methyl esters of 1 -oxo-indanoyl-leucine, coronalon (2-[(6-ethyl-l-oxo-indane-4-carbonyl) -amino]-3-methyl -pentanoic acid methyl ester), linoleic acid or derivatives thereof and cis-jasmone, or combinations of any of the above.

Humates are humic and fulvic acids extracted from a form of lignite coal and clay, known as leonardite. Humic acids are organic acids that occur in humus and other organically derived materials such as peat and certain soft coal. They have been shown to increase fertilizer efficiency in phosphate and micro-nutrient uptake by plants as well as aiding in the development of plant root systems. According to one embodiment of the inventive mixtures, the at least one pesticide II is selected from the groups L1 ) to L6):

L1 ) Microbial pesticides with fungicidal, bactericidal, viricidal and/or plant defense activator activity: Ampelomyces quisqualis M-10 (L.1 .1 ), Aspergillus flavus NRRL 21882 (L1 .2), Aureobasidium pullulans DSM 14940 (L1 .3), A. pullulans DSM 14941 (L.1.4), Bacillus amyloliquefaciens AP-136 (NRRL B-50614) (L.1 .5), B.

amyloliquefaciens AP-188 (NRRL B-50615) (L.1.6), B. amyloliquefaciens AP-218 (NRRL B-50618) (L.1.7), B. amyloliquefaciens AP-219 (NRRL B-50619) (L.1 .8), B. amyloliquefaciens AP-295 (NRRL B-50620) (L.1.9), B. amyloliquefaciens FZB42 (L.1.10), B. amyloliquefaciens IN937a (L.1.1 1 ), B. amyloliquefaciens IT-45 (CNCM I-3800) (L.1 .12), B. amyloliquefaciens subsp. plantarum MBI600 (NRRL B-50595) (L.1 .13), B. mojavensis AP-209 (NRRL B-50616) (L.1 .15), B. pumilus INR-7 (otherwise referred to as BU-F22 (NRRL B-50153) and BU-F33 (NRRL B-50185)) (L.1.14), B. pumilus KFP9F (L.1.15), B. pumilus QST 2808 (NRRL B-30087) (L.1 .16), B. pumilus GHA 181 (L.1.17), B. simplex ABU 288 (NRRL B-50340) (L.1 .18), B. solisalsi AP-217 (NRRL B-50617) (L.1.19), B. subtilis CX-9060 (L.1.20), B. subtilis GB03 (L.1.21 ), B. subtilis GB07 (L.1 .22), B. subtilis QST-713 (NRRL B-21661 ) (L.1 .23), B. subtilis var. amyloliquefaciens FZB24 (L.1 .24), B. subtilis var. amyloliquefaciens D747 (L.1.25), Candida oleophila I-82 (L.1 .26), C. oleophila O (L.1.27), C. saitoana (L.1.28),

Clavibacter michiganensis (bacteriophages) (L.1.29), Coniothyrium minitans

CON/M/91 -08 (L.1.30), Cryphonectria parasitica (L.1.31 ), Cryptococcus albidus (L.1.32), Dilophosphora alopecuri (L.1.33), Fusarium oxysporum (L.1.34),

Clonostachys rosea f. catenulata J 1446 (also named Gliocladium catenulatum) (L.1 .35), Gliocladium roseum 321 U (L.1 .36), Metschnikowia fructicola NRRL Y-30752 (L.1.37), Microdochium dimerum (L.1.38), Microsphaeropsis ochracea P130A (L.1.39), Muscodor albus QST 20799 (L.1.40), Paenibacillus polymyxa PKB1 (ATCC 202127) (L.1.41 ), Pantoea vagans C9-1 (L.1.42), Phlebiopsis gigantea (L.1.43), Pichia anomala WRL-76 (L.1 .44), Pseudozyma flocculosa PF-A22 UL (L.1 .45), Pythium oligandrum DV 74 (L.1 .46), Sphaerodes mycoparasitica IDAC 301008-01 (L.1 .47), Streptomyces griseoviridis K61 (L.1.48), S. lydicus WYEC 108 (L.1 .49), S. violaceusniger XL-2 (L.1.50), S. violaceusniger YCED-9 (L.1.51 ), Talaromyces flavus V1 17b (L.1.52), Trichoderma asperellum T34 (L.1 .53), T. asperellum SKT-1 (L.1 .54), T. asperellum ICC 012 (L.1.55), T. atroviride LC52 (L.1.56), T. atroviride CNCM 1-1237 (L.1.57), T. fertile JM41 R (L.1.58), T. gamsii ICC 080 (L.1 .59), T. harmatum TH 382 (L.1 .60), T.

harzianum TH-35 (L.1 .61 ), T. harzianum T-22 (L.1 .62), T. harzianum T-39 (L.1 .63); mixture of T. harzianum ICC012 and T. viride ICC080 (L.1 .64); mixture of T.

polysporum and T. harzianum (L.1.65); T. stromaticum (L.1 .66), T. virens (also named Gliocladium virens) GL-21 (L.1 .67), T. virens G41 (L.1.68), T. viride TV1 (L.1 .69), Typhula phacorrhiza 94671 (L.1.70), Ulocladium oudemansii HRU3 (L.1.71 ),

Verticillium dahlia (L.1.72), zucchini yellow mosaic virus (avirulent strain) (L.1 .73); L2) Biochemical pesticides with fungicidal, bactericidal, viricidal and/or plant defense activator activity: chitosan (hydrolysate) (L.2.1 ), harpin protein (L.2.2), laminarin (L.2.3), Menhaden fish oil (L.2.4), natamycin (L.2.5), Plum pox virus coat protein (L.2.6), potassium bicarbonate (L.2.7), Reynoutria sachlinensis extract (L.2.8), salicylic acid (L.2.9), potassium or sodium bicarbonate (L.2.10), tea tree oil (L.2.1 1 );

L3) Microbial pesticides with insecticidal, acaricidal, molluscidal and/or nematicidal activity: Agrobacterium radiobacter K1026 (L.3.1 ), A radiobacter K84 (L.3.2), Bacillus firmus 1-1582 (L.3.3); B. thuringiensis ssp. aizawai strains ABTS-1857 (L.3.4), SAN 401 I (L.3.5), ABG-6305 (L.3.6) and ABG-6346 (L.3.7); B. t. ssp. israelensis AM65-52 (L.3.8), B. t. ssp. israelensis SUM-6218 (L.3.9), B. t. ssp. galleriae SDS-502 (L.3.10), B. t. ssp. kurstaki EG 2348 (L.3.1 1 ), B. t. ssp. kurstaki SB4 (L.3.12), B. t. ssp. kurstaki ABTS-351 (HD-1 ) (L.3.13), Beauveria bassiana ATCC 74040 (L.3.14), B. bassiana GHA (L.3.15), B. bassiana H123 (L.3.16), B. bassiana DSM 12256 (L.3.17), B.

bassiana PPRI 5339 (L.3.18), B. brongniartii (L.3.19), Burkholderia sp. A396 (L.3.20), Chromobacterium subtsugae PRAA4-1 (L.3.21 ), Cydia pomonella granulosis virus V22 (L.3.22), Cydia pomonella granulosis virus V1 (L.3.23), Isaria fumosorosea Apopka-97 (L.3.24), Lecanicillium longisporum KV42 (L.3.25), L. longisporum KV71 (L.3.26), L. muscarium (formerly Verticillium lecanii) KV01 (L.3.27), Metarhizium anisopliae FI-985 (L.3.28), M. anisopliae FI-1045 (L.3.29), M. anisopliae F52 (L.3.30), M. anisopliae ICIPE 69 (L.3.31 ), M. anisopliae var. acridum IMI 330189 (L.3.32); Nomuraea rileyi strains SA86101 (L.3.33), GU87401 (L.3.34), SR86151 (L.3.35), CG128 (L.3.36) and VA9101 (L.3.37); Paecilomyces fumosoroseus FE 9901 (L.3.38), P. lilacinus 251 (L.3.39), P. lilacinus DSM 15169 (L.3.40), P. lilacinus BCP2 (L.3.41 ), Paenibacillus popilliae Dutky-1940 (NRRL B-2309 = ATCC 14706) (L.3.42), P. popilliae KLN 3, P. popilliae Dutky 1 (L.3.43), Pasteuria spp. Ph3 (L.3.44), Pasteuria spp. ATCC PTA-9643 (L.3.45), Pasteuria spp. ATCC SD-5832 (L.3.46), P. nishizawae PN-1 (L.3.46), P.

penetrans (L.3.47), P. ramose (L.3.48), P. reneformis Pr-3 (L.3.49), P. thornea (L.3.50), P. usgae (L.3.51 ), Pseudomonas fluorescens CL 145A (L.3.52), Steinernema carpocapsae (L.3.53), S. feltiae (L.3.54), S. kraussei L137 (L.3.55);

L4) Biochemical pesticides with insecticidal, acaricidal, molluscidal, pheromone and/or nematicidal activity: L-carvone (L.4.1 ), citral (L.4.2), (E,Z)-7,9-dodecadien-1 -yl acetate (L.4.3), ethyl formate (L.4.4), (E,Z)-2,4-ethyl decadienoate (pear ester) (L.4.5), (Z,Z,E)-7,1 1 ,13-hexadecatrienal (L.4.6), heptyl butyrate (L.4.7), isopropyl myristate (L.4.8), cis-jasmone (L.4.9), lavanulyl senecioate (L.4.10), 2-methyl 1 -butanol (L.4.1 1 ), methyl eugenol (L.4.12), methyl jasmonate (L.4.13), (E,Z)-2,13-octadecadien-1 -ol (L.4.14), (E,Z)-2,13-octadecadien-1 -ol acetate (L.4.15), (E,Z)-3,13-octadecadien-1 -ol (L.4.16), R-1 -octen-3-ol (L.4.17), pentatermanone (L.4.18), potassium silicate (L.4.19), sorbitol actanoate (L.4.20), (E,Z,Z)-3,8,1 1 -tetradecatrienyl acetate (L.4.21 ), (Z,E)-9,12- tetradecadien-1 -yl acetate (L.4.22), Z-7-tetradecen-2-one (L.4.23), Z-9-tetradecen-1 -yl acetate (L.4.24), Z-1 1 -tetradecenal (L.4.25), Z-1 1 -tetradecen-1 -ol (L.4.26), Acacia negra extract (L.4.27), extract of grapefruit seeds and pulp (L.4.28), extract of

Chenopodium ambrosiodae (L.4.29), Catnip oil (L.4.30), Neem oil (L.4.31 ), Quillay extract (L.4.32), Tagetes oil (L.4.33);

L5) Microbial pesticides with plant stress reducing, plant growth regulator, plant growth promoting and/or yield enhancing activity: Azospirillum amazonense BR 1 1 140 (SpY2^T) (L.5.1 ), A. brasilense AZ39 (L.5.2), A. brasilense XOH (L.5.3), A. brasilense BR 1 1005 (Sp245) (L.5.4), A. brasilense BR 1 1002 (L.5.5), A. lipoferum BR 1 1646 (Sp31 ) (L.5.6), A. irakense (L.5.7), A. halopraeferens (L.5.8), Bradyrhizobium sp.

PNL01 (L.5.9), B. sp. (Arachis) CB1015 (L.5.10), B. sp. (Arachis) USDA 3446 (L.5.1 1 ), B. sp. (Arachis) SEMIA 6144 (L.5.12), B. sp. (Arachis) SEMIA 6462 (L.5.13), B. sp. (Arachis) SEMIA 6464 (L.5.14), B. sp. (Vigna) (L.5.15), B. elkanii SEMIA 587 (L.5.16), B. elkanii SEMIA 5019 (L.5.17), B. elkanii U-1301 (L.5.18), B. elkanii U-1302 (L.5.19), B. elkanii USDA 74 (L.5.20), B. elkanii USDA 76 (L.5.21 ), B. elkanii USDA 94 (L.5.22), B. elkanii USDA 3254 (L.5.23), B. japonicum 532c (L.5.24), B. japonicum CPAC 15 (L.5.25), B. japonicum E-109 (L.5.26), B. japonicum G49 (L.5.27), B. japonicum TA-1 1 (L.5.28), B. japonicum USDA 3 (L.5.29), B. japonicum USDA 31 (L.5.30), B. japonicum USDA 76 (L.5.31 ), B. japonicum USDA 1 10 (L.5.32), B. japonicum USDA 121 (L.5.33), B. japonicum USDA 123 (L.5.34), B. japonicum USDA 136 (L.5.35), B. japonicum SEMIA 566 (L.5.36), B. japonicum SEMIA 5079 (L.5.37), B. japonicum SEMIA 5080 (L.5.38), B. japonicum WB74 (L.5.39), B. liaoningense (L.5.40), B. lupini LL13 (L.5.41 ), B. lupini WU425 (L.5.42), B. lupini WSM471 (L.5.43), B. lupini WSM4024 (L.5.44), Glomus intraradices RTI-801 (L.5.45), Mesorhizobium sp. WSM1271 (L.5.46), M. sp. WSM1497 (L.5.47), M. ciceri CC1 192 (L.5.48), M. huakii (L.5.49), M. loti CC829 (L.5.50), M. loti SU343 (L.5.51 ), Paenibacillus alvei NAS6G6 (L.5.52), Penicillium bilaiae (L.5.53), Rhizobium leguminosarum bv. phaseoli RG-B10 (L.5.54), R. I. bv. trifolii RP1 13-7 (L.5.55), R. I. bv. trifolii 095 (L.5.63), R. I. bv. trifolii TA1 (L.5.64), R. I. bv. trifolii CC283b (L.5.65), R. I. bv. trifolii CC275e (L.5.66), R. I. bv. trifolii CB782 (L.5.67), R. I. bv. trifolii CC1099 (L.5.68), R. I. bv. trifolii WSM1325 (L.5.69), R. I. bv. viciae SU303 (L.5.56), R. I. bv. viciae WSM1455 (L.5.57), R. I. bv. viciae P1 NP3Cst (L.5.58), R. I. bv. viciae RG-P2 (L.5.70), R. tropici SEMIA 4080 (L.5.59), R. tropici SEMIA 4077 (L.5.71 ), R. tropici CC51 1 (L.5.72), Sinorhizobium meliloti MSDJ0848 (L.5.60), S. meliloti NRG185 (L.5.61 ), S. meliloti RRI128 (L.5.62);

L6) Biochemical pesticides with plant stress reducing, plant growth regulator and/or plant yield enhancing activity: abscisic acid (L.6.1 ), aluminium silicate (kaolin) (L.6.2), 3-decen-2-one (L.6.3), formononectin (L.6.4), genistein (L.6.5), hesperetin (L.6.6), homobrassinlide (L.6.7), humates (L.6.8), methyl jasmonate (L.6.9), cis-jasmone (L.6.10), lysophosphatidyl ethanlamine (L.6.1 1 ), naringenin (L.6.12), polymeric polyhydroxy acid (L.6.13), salicylic acid (L.6.14), Ascophyllum nodosum (Norwegian kelp, Brown kelp) extract (L.6.15) and Ecklonia maxima (kelp) extract (L.6.16).

The present invention furthermore relates to agrochemical compositions comprising a mixture of compounds of formula I (component 1 ) and at least one biopesticide selected from the group L) (component 2), in particular at least one further fungicidal biopesticide selected from the groups L1 ) and L2), as described above, and if desired at least one suitable auxiliary.

Preference is also given to mixtures comprising as pesticide II (component 2) a biopesticide from group L1 ), preferably selected from Bacillus amyloliquefaciens AP- 136 (NRRL B-50614 and B-50330), B. amyloliquefaciens AP-188 (NRRL B-50615 and B-50331 ), B. amyloliquefaciens AP-218 (NRRL B-50618), B. amyloliquefaciens AP-219 (NRRL B-50619 and B-50332), B. amyloliquefaciens AP-295 (NRRL B-50620 and B- 50333), B. amyloliquefaciens IT-45 (CNCM I-3800), B. amyloliquefaciens subsp.

plantarum MBI600 (NRRL B-50595), B. mojavensis AP-209 (NRRL B-50616), B.

pumilus INR-7 (otherwise referred to as BU-F22 (NRRL B-50153) and BU-F33 (NRRL B-50185)), B. pumilus KFP9F, B. pumilus QST 2808 (NRRL B-30087), B. pumilus GHA 181 , B. simplex ABU 288 (NRRL B-50340), B. solisalsi AP-217 (NRRL B-50617), B. subtilis CX-9060, B. subtilis GB03, B. subtilis GB07, B. subtilis QST-713 (NRRL B- 21661 ), B. subtilis var. amyloliquefaciens FZB24, B. subtilis var. amyloliquefaciens D747, Paenibacillus alvei NAS6G6, Paenibacillus polymyxa PKB1 (ATCC 202127), Sphaerodes mycoparasitica IDAC 301008-01 and Trichoderma fertile JM41 R, even more preferably from Bacillus amyloliquefaciens AP-136 (NRRL B-50614), B.

amyloliquefaciens AP-188 (NRRL B-50615), B. amyloliquefaciens AP-218 (NRRL B- 50618), B. amyloliquefaciens AP-219 (NRRL B-50619), B. amyloliquefaciens AP-295 (NRRL B-50620), B. amyloliquefaciens IT-45 (CNCM I-3800), B. mojavensis AP-209 (NRRL B-50616), B. pumilus INR-7 (otherwise referred to as BU-F22 (NRRL B-50153) and BU-F33 (NRRL B-50185)), B. pumilus QST 2808 (NRRL B-30087), B. simplex ABU 288 (NRRL B-50340), B. subtilis QST-713 (NRRL B-21661 ), B. subtilis MBI600 (NRRL B-50595), Paenibacillus alvei NAS6G6, Sphaerodes mycoparasitica IDAC 301008-01 and Trichoderma fertile JM41 R.

According to one embodiment of the inventive mixtures, the at least one pesticide II is Bacillus amyloliquefaciens subsp. plantarum MBI600. These mixtures are particularly suitable in soybean.

According to another embodiment of the inventive mixtures, the at least one pesticide II is B. pumilus strain INR-7. These mixtures are particularly suitable in soybean and corn.

According to a further embodiment, the at least one pesticide II is Bacillus simplex, preferably B. simplex strain ABU 288. These mixtures are particularly suitable in soybean and corn.

According to one embodiment of the inventive mixtures, the at least one pesticide II is selected from Bacillus amyloliquefaciens AP-136, B. amyloliquefaciens AP-188, B. amyloliquefaciens AP-218, B. amyloliquefaciens AP-219, B. amyloliquefaciens AP-295, B. amyloliquefaciens FZB42, B. amyloliquefaciens IN937a, B. amyloliquefaciens IT-45, B. amyloliquefaciens subsp. plantarum MBI600, B. mojavensis AP-209, B. pumilus GB34, B. pumilus INR-7, B. pumilus KFP9F, B. pumilus QST 2808, B. pumilus GHA 181 , B. simplex ABU 288, B. solisalsi AP-217, B. subtilis CX-9060, B. subtilis GB03, B. subtilis GB07, B. subtilis QST-713, B. subtilis var. amyloliquefaciens FZB24 and B. subtilis var. amyloliquefaciens D747. These mixtures are particularly suitable in soybean and corn, in particular for seed treatment.

According to a further embodiment, the at least one pesticide II is selected from

Streptomyces spp. Preferably from S. griseoviridis, S. lydicus and S. violaceusniger, in particular from strains S. griseoviridis K61 , S. lydicus WYEC 108, S. violaceusniger XL- 2 and S. violaceusniger YCED-9.

According to a further embodiment, the at least one pesticide II is Sphaerodes mycoparasitica, preferably Sphaerodes mycoparasitica strain IDAC 301008-01 (also referred to as strain SMCD2220-01 ). These mixtures are particularly suitable in soybean, cereals and corn, in particular corn especially to combat Fusarium head blight. The present invention also relates to mixtures wherein the at least one pesticide II is selected from the following yests and fungi: Ampelomyces quisqualis, in particular strain AQ 10, Aureobasidium pullulans, in particular blastospores of strain DSM14940 or blastospores of strain DSM 14941 or mixtures thereof; Candida oleophila, in particular strains 1-182 and O, Coniothyrium minitans, in particular strain CON/M/91 -8; Dilophosphora alopecuri which reduces annual ryegrass toxicity (ARGT), a disease of livestock resulting from the ingestion of annual ryegrass seed-heads that have been infected by the toxin producing bacterium Rathayibacter toxicus; Gliocladium catenulatum, in particular strain J 1446; Metschnikovia fructicola, in particular strain NRRL Y-30752, Microsphaeropsis ochracea, in particular strain P130A for control of apple scab; (2.13) Muscodor albus, in particular strain QST 20799, Pichia anomala, in particular strain WRL-076, Pseudozyma flocculosa, in particular strain PF-A22 UL; Pythium oligandrum, in particular strain DV74;

The present invention also relates to mixtures wherein the at least one pesticide II is selected from the fungal genus Trichoderma, preferably from the strains Trichoderma asperellum T34, T. asperellum SKT-1 , T. asperellum ICC 012, T. atroviride LC52, T. atroviride CNCM 1-1237, T. fertile JM41 R, T. gamsii ICC 080, T. harmatum TH 382, T. harzianum TH-35, T. harzianum T-22, T. harzianum T-39, ; mixture of T. harzianum

ICC012 and T. viride ICC080; mixture of T. polysporum and T. harzianum; T.

stromaticum, T. virens GL-21 , T. virens G41 and T. viride TV1 ; in particular T. fertile

JM41 R.

The present invention also relates to mixtures wherein the at least one pesticide II is selected from the fungal genus Ulocladium, in particular U. oudemansii HRU3. Preference is also given to mixtures comprising as pesticide II (component 2) a biopesticide from group L2), preferably selected from chitosan (hydrolysate), methyl- jasmonate, cis-jasmone, laminarin, Reynoutria sachlinensis extract and tea tree oil; even more preferable from methyl jasmonate and laminarin. Preference is also given to mixtures comprising as pesticide II (component 2) a biopesticide from group L3), preferably selected from Agrobacterium radiobacter K1026, Bacillus firmus 1-1582, Bacillus thuringiensis ssp. kurstaki SB4, Beauveria bassiana GHA, B. bassiana H123, B. bassiana DSM 12256, B. bassiana PPRI 5339, Metarhizium anisopliae var. acridum IMI 330189, M. anisopliae FI-985, M. anisopliae FI-1045, M. anisopliae F52, M. anisopliae ICIPE 69, Paecilomyces lilacinus DSM

15169, P. lilacinus BCP2, Paenibacillus popilliae Dutky-1940 (NRRL B-2309 = ATCC 14706), P. popilliae KLN 3 and P. popilliae Dutky 1 , even more preferably from Bacillus thuringiensis ssp. kurstaki SB4, B. bassiana DSM 12256, B. bassiana PPRI 5339, Metarhizium anisopliae var. acridum IMI 330189, M. anisopliae FI-985, M. anisopliae FI-1045, Paecilomyces lilacinus DSM 15169, P. lilacinus BCP2, Paenibacillus popilliae Dutky-1940 (NRRL B-2309 = ATCC 14706), P. popilliae KLN 3 and P. popilliae Dutky 1 . According to a further embodiment, the at least one pesticide II is Beauveria bassiana, preferably selected from Beauveria bassiana ATCC 74040, B. bassiana GHA, B. bassiana H123, B. bassiana DSM 12256 and B. bassiana PPRI 5339, in particular Beauveria bassiana strain PPRI 5339. These mixtures are particularly suitable for wide range of arthropod pests, such as white flies, thrips, mites, aphids, tingids and all their developmental stages (eggs, immature stages, and adults) infesting numerous crops (vegetables, cucurbits, solanaceous fruits, strawberry, flowers and ornamentals, grapevine, citrus, pome, stone fruits, etc.). Recent studies have shown that these antagonistic fungal strains can effectively control also nut-weevils, wireworms (Agriotes spp.), and Tephritid flies, such as the Mediterranean fruit fly, Ceratitis capitata, the cherry fruit fly, Rhagoletis cerasi, and the olive fly, Bactrocera oleae. They are also useful in soybean and corn.

According to a further embodiment, the at least one pesticide II is Beauveria brongniartii.

According to a further embodiment, the at least one pesticide II is Metarhizium anisopliae or M. anisopliae var. acridium, preferably selected from M. anisopliae Fl- 1045, M. anisopliae F52, M. anisopliae var. acridum strains FI-985 and IMI 330189, in particular strain IMI 330189. These mixtures are particularly suitable for control of arthropod pests in soybean and corn.

According to a further embodiment, the at least one pesticide II is Lecanicillium sp., preferably selected from Lecanicillium longisporum KV42, L. longisporum KV71 and L. muscarium (formerly Verticillium lecanii) KV01 .

According to a further embodiment, the at least one pesticide II is Paecilomyces fumosoroseus, preferably strain FE 9901 especially for white fly control.

According to a further embodiment, the at least one pesticide II is selected from Nomuraea rileyi, preferably strains SA86101 , GU87401 , SR86151 , CG128 and VA9101 ; and P. lilacinus, preferably strains 251 , DSM 15169 or BCP2, in particular BCP2, which strains especially control the growth of plant-pathogenic nematodes. According to a further embodiment, the at least one pesticide II is Bacillus firmus, preferably spores of strain CNCM 1-1582, preferable for seed treatment of soybean and corn against nematodes and insects.

According to a further embodiment, the at least one pesticide II is B. cereus preferably spores of CNCM 1-1562, preferable for seed treatment of soybean and corn against nematodes and insects.

According to a further embodiment, the at least one pesticide II is a mixture of spores of B. firmus and B. cereus, preferably mixtures spores of strains CNCM 1-1582 and CNCM 1-1562, preferable for seed treatment of soybean and corn against nematodes and insects.

According to a further embodiment, the at least one pesticide II is selected from Bacillus thuringiensis, preferably B. thuringiensis ssp. aizawai, in particular B. t. ssp. aizawai strains ABTS-18, SAN 401 I, ABG-6305 and ABG-6346, which are effective against different lepidopteran species including also noctuidae. According to a further embodiment, the at least one pesticide II is selected from Bacillus t. ssp. israelensis, preferably AM65-52, SAN 402 I and ABG-6164, which are applied against larvae of various dipteran pests, e.g. mosquitoes and nematoceres. According to a further embodiment, the at least one pesticide II is selected from Bacillus t. ssp. kurstaki preferably from strains EG 2348, SB4 and ABTS-351 (HD-1 ), in particular B. thuringiensis ssp. kurstaki SB4. These strains are used for control of lepidopteran larvae, but without noctuidae.

According to a further embodiment, the at least one pesticide II is selected from Bacillus thuringiensis subsp. tenebrionis, preferably the strains DSM 2803, NB-125 and NB-176, in particular NB-176, which all protect plants e.g. against leaf beetle larvae.

Preference is also given to mixtures comprising as pesticide II (component 2) a biopesticide from group L4), preferably selected from methyl jasmonate, Acacia negra extract, extract of grapefruit seeds and pulp, Catnip oil, Neem oil, Quillay extract and Tagetes oil, in particular methyl jasmonate or water-based Quillay extract.

Preference is also given to mixtures comprising as pesticide II (component 2) a biopesticide from group L5), preferably selected from Azospirillum amazonense BR 1 1 140 (SpY2^T), A. brasilense XOH, A. brasilense BR 1 1005 (Sp245), A. brasilense BR 1 1002, A. lipoferum BR 1 1646 (Sp31 ), A. irakense, A. halopraeferens, Bacillus amyloliquefaciens AP-136 (NRRL B-50614), Bradyrhizobium sp. (Vigna), B. japonicum USDA 3, B. japonicum USDA 31 , B. japonicum USDA 76, B. japonicum USDA 1 10, B. japonicum USDA 121 , Glomus intraradices RTI-801 , Paenibacillus alvei NAS6G6, Penicillium bilaiae, Rhizobium leguminosarum bv. phaseoli, R. I. trifolii, R. I. bv. viciae, and Sinorhizobium meliloti, more preferably selected from Azospirillum brasilense BR 1 1005 (Sp245), Bradyrhizobium sp. (Vigna), B. japonicum USDA 3, B. japonicum USDA 31 , B. japonicum USDA 76, B. japonicum USDA 1 10, B. japonicum USDA 121 , Rhizobium leguminosarum bv. phaseoli, R. I. trifolii RP1 13-7, R. I. bv. viciae SU303, R. I. bv. viciae WSM1455, R. tropici SEMIA 4077, R. tropici SEMIA 4080 and

Sinorhizobium meliloti.

According to another embodiment of the inventive mixtures, Bradyrhizobium sp.

(meaning any Bradyrhizobium species and/or strain) as pesticide II is Bradyrhizobium japonicum (B. japonicum). These mixtures are particularly suitable in soybean. B. japonicum strains were cultivated using media and fermentation techniques known in the art, e.g. in yeast extract-mannitol broth (YEM) at 27°C for about 5 days.

The present invention also relates to mixtures, wherein the at least one pesticide II is selected from Bradyrhizobium japonicum (B. japonicum) and further comprisies a compound III, wherein compound III is selected from jasmonic acid or salts or derivatives thereof including cis-jasmone, preferably methyl-jasmonate or cis-jasmone. References for various B. japonicum strains are given e.g. in US 7,262,151 (B.

japonicum strains USDA 1 10 (= IITA 2121 , SEMIA 5032, RCR 3427, ARS 1-1 10, Nitragin 61A89; isolated from Glycine max in Florida in 1959, Serogroup 1 10; Appl Environ Microbiol 60, 940-94, 1994), USDA 31 (= Nitragin 61A164; isolated from Glycine max in Wisoconsin in 1941 , USA, Serogroup 31 ), USDA 76 (plant passage of strain USDA 74 which has been isolated from Glycine max in California, USA, in 1956, Serogroup 76), USDA 121 (isolated from Glycine max in Ohio, USA, in 1965), USDA 3 (isolated from Glycine max in Virginia, USA, in 1914, Serogroup 6), USDA 121 (Crop Science 26(5), 91 1 -916, 1986) and USDA 136 (= CB 1809, SEMIA 586, Nitragin 61A136, RCR 3407; isolated from Glycine max in Beltsville, Maryland in 1961 ; Appl Environ Microbiol 60, 940-94, 1994). Further suitable B. japonicum strain G49 (INRA, Angers, France) is described in Fernandez-Flouret, D. & Cleyet-Marel, J. C. (1987) C R Acad Agric Fr 73, 163-171 ), especially for soybean grown in Europe, in particular in France. Further suitable B. japonicum strain TA-1 1 (TA1 1 NOD⁺) (NRRL B-18466) is i.a. described in US 5,021 ,076; Appl Environ Microbiol (1990) 56, 2399-2403 and commercially available as liquid inoculant for soybean (VAULT® NP, Becker

Underwood, USA). Further B. japonicum strains as example for pesticide II are described in US2012/0252672A. Further suitable and especially in Canada

commercially available strain 532c (The Nitragin Company, Milwaukee, Wisconsin, USA, field isolate from Wisconsin; Nitragin strain collection No. 61A152; Can J Plant Sci 70 (1990), 661 -666) (e.g. in RHIZOFLO, HISTICK, HICOAT Super from Becker Underwood, Canada). Preferably, B. japonicum is selected from strains TA-1 1 and 532c, more preferably a mixture of B. japonicum strains TA-1 1 and 532c.

Other suitable and commercially available B. japonicum strains (see e.g. Appl Environ Microbiol 2007, 73(8), 2635) are SEMIA 566 (isolated from North American inoculant in 1966 and used in Brazilian commercial inoculants from 1966 to 1978), SEMIA 586 (= CB 1809; originally isolated in Maryland, USA but received from Austrailia in 1966 and used in Brazilian inoculants in 1977), CPAC 15 (= SEMIA 5079; a natural varaiant of SEMIA 566 used in commercial inoculants since 1992) and CPAC 7 (= SEMIA 5080; a natural variant of SEMIA 586 used in commercial inoculants since 1992). These strains are especially suitable for soybean grown in Australia or South America, in particular in Brazil. In particular, mixtures of B. japonicum SEMIA 5079 and SEMIA 5080 are suitable. Some of the abovementioned strains have been re-classified as a novel species Bradyrhizobium elkanii, e.g. strain USDA 76 (Can. J. Microbiol., 1992, 38, 501 - 505).

Another suitable and commercially available B. japonicum strain is E-109 (variant of strain USDA 138, see e.g. Eur. J. Soil Biol. 45 (2009) 28-35; Biol Fertil Soils (201 1 ) 47:81-89, deposited at Agriculture Collection Laboratory of the Instituto de

Microbiologia y Zoologia Agncola (IMYZA), Instituto Nacional de Tecnologi^'a

Agropecuaria (INTA), Castelar, Argentina). This strain is especially suitable for soybean grown in South America, in particular in Argentina.

Another suitable and commercially available B. japonicum strain are WB74 or WB74-1 (e.g. from Stimuplant CC, South Africa or from SoyGro Bio-Fertilizer Ltd, South Africa). These strains are especially suitable for soybean grown in South America and Africa, in particular in South Africa.

The present invention also relates to mixtures, wherein the at least one pesticide II is selected from Bradyrhizobium elkanii and Bradyrhizobium liaoningense (B. elkanii and B. liaoningense), more preferably from B. elkanii. These mixtures are particularly suitable in soybean. B. elkanii and liaoningense were cultivated using media and fermentation techniques known in the art, e.g. in yeast extract-mannitol broth (YEM) at 27°C for about 5 days.

The present invention also relates to mixtures wherein the at least one pesticide II is selected from selected from B. elkanii and B. liaoningense and further comprises a compound III, wherein compound III is selected from jasmonic acid or salts or derivatives thereof including cis-jasmone, preferably methyl-jasmonate or cis-jasmone. Suitable and commercially available B. elkanii strains are SEMIA 587 and SEMIA 5019 (=29W) (see e.g. Appl Environ Microbiol 2007, 73(8), 2635) and USDA 3254 and USDA 76 and USDA 94. Preferably, mixtures of B. elkanii strains SEMIA 587 and SEMIA 5019 are useful (e.g. in Gelfix 5 from Nitral Urbana Laboratories, Brazil, a BASF Company). Further commercially available B. elkanii strains are U-1301 and U-1302 (e.g. product Nitroagin® Optimize from Novozymes Bio As S.A., Brazil or NITRASEC for soybean from LAGE y Cia, Brazil). These strains are especially suitable for soybean grown in Australia or South America, in particular in Brazil.

The present invention also relates to mixtures, wherein pesticide II is selected from Bradyrhizobium sp. (Arachis) (B. sp. Arachis) which shall describe the cowpea miscellany cross-inoculation group which includes inter alia indigenous cowpea bradyrhizobia on cowpea (Vigna unguiculata), siratro (Macroptilium atropurpureum), lima bean (Phaseolus lunatus), and peanut (Arachis hypogaea). This mixture comprising as pesticide II B. sp. Arachis is especially suitable for use in peanut, Cowpea, Mung bean, Moth bean, Dune bean, Rice bean, Snake bean and Creeping vigna, in particular peanut.

The present invention also relates to mixtures wherein the at least one pesticide II is selected from B. sp. (Arachis) and further comprises a compound III, wherein compound III is selected from jasmonic acid or salts or derivatives thereof including cis- jasmone, preferably methyl-jasmonate or cis-jasmone.

Suitable and commercially available B. sp. (Arachis) strain is CB1015 (= IITA 1006, USDA 3446 presumably originally collected in India; from Australian Inoculants

Research Group; see e.g. http://www.qaseeds.com.au/inoculant_applic.php). These strains are especially suitable for peanut grown in Australia, North America or South America, in particular in Brazil. Further suitable strain is Bradyrhizobium sp. PNL01 (Becker Underwood, ; Bisson and Mason, April 29, 2010, Project report, Worcester Polytechnic Institute, Worcester, MA, USA: http://www.wpi.edu/Pubs/E- project/Available/E-project-042810-163614/).

Suitable and commercially available Bradyrhizobium sp. (Arachis) strains especially for cowpea and peanut but also for soybean are Bradyrhizobium SEMIA 6144, SEMIA 6462 (= BR 3267) and SEMIA 6464 (= BR 3262; see e.g. FEMS Microbiology Letters (2010) 303(2), 123-131 ; Revista Brasileira de Ciencia do Solo (201 1 ) 35(3);739-742, ISSN 0100-0683). The present invention also relates to mixtures, wherein the at least one pesticide II is selected from Bradyrhizobium sp. (Lupine) (also called B. lupini, B. lupines or

Rhizobium lupini). This mixture is especially suitable for use in dry beans and lupins. The present invention also relates to mixtures wherein the at least one pesticide II is selected from Bradyrhizobium sp. (Lupine) (B. lupini) and further comprises a compound III, wherein compound III is selected from jasmonic acid or salts or derivatives thereof including cis-jasmone, preferably methyl-jasmonate or cis-jasmone. Suitable and commercially available B. lupini strain is LL13 (isolated from Lupinus iuteus nodules from French soils; deposited at INRA, Dijon and Angers, France;

http://agriculture.gouv.fr/IMG/pdf/ch20060216.pdf). This strain is especially suitable for lupins grown in Australia, North America or Europe, in particular in Europe.

Further suitable and commercially available B. lupini strains WU425 (isolated in Esperance, Western Australia from a non-Australian legume Ornthopus compressus), WSM4024 (isolated from lupins in Australia by CRS during a 2005 survey) and

WSM471 (isolated from Ornithopus pinnatus in Oyster Harbour, Western Australia) are described e.g. in Palta J.A. and Berger J.B. (eds), 2008, Proceedings 12^th International Lupin Conference, 14-18 Sept. 2008, Fremantle, Western Australia. International Lupin Association, Canterbury, New Zealand, 47-50, ISBN 0-86476-153-8:

http://www.lupins.org/pdf/conference/2008/Agronomy%20and%20Production/John%20 Howieson%20and%20G%20OHara.pdf; Appl. Environ. Microbiol. 71 , 7041 -7052, 2005; Australian J. Exp. Agricult. 36(1 ), 63-70, 1996.

The present invention also relates to mixtures, wherein the at least one pesticide II is selected from Mesorhizobium sp. (meaning any Mesorhizobium species and/or strain), more preferably Mesorhizobium ciceri. These mixtures are particularly suitable in cowpea.

The present invention also relates to mixtures wherein the at least one pesticide II is selected from Mesorhizobium sp. and further comprises a compound III, wherein compound III is selected from jasmonic acid or salts or derivatives thereof including cis- jasmone, preferably methyl-jasmonate or cis-jasmone.

Suitable and commercially available Mesorhizobium sp. strains are e.g. M. ciceri CC1 192 (=UPM 848, CECT 5549; from Horticultural Research Station, Gosford, Australia; collected in Israel from Cicer arietinum nodules; Can J Microbial (2002) 48, 279-284) and Mesorhizobium sp. strains WSM1271 (collected in Sardinia, Italy, from plant host Biserrula pelecinus), WSM 1497 (collected in Mykonos, Greece, from plant host Biserrula pelecinus), M. loti strains CC829 (commerical inoculant for Lotus pedunculatus and L. ulginosus in Australia, isolated from L. ulginosus nodules in USA; NZP 2012), M. loti SU343 (a commercial inoculant for Lotus corniculatus in Australia; isolated from host nodules in USA). For references see e.g. Soil Biol Biochem (2004) 36(8), 1309-1317; Plant and Soil (201 1 ) 348(1 -2), 231 -243).

Suitable and commercially available M. loti strains are e.g. M. loti CC829 for Lotus pedunculatus.

The present invention also relates to mixtures wherein the at least one pesticide II is selected from Mesorhizobium huakuii, also referred to as Rhizobium huakuii (see e.g. Appl. Environ. Microbiol. 201 1 , 77(15), 5513-5516). These mixtures are particularly suitable in Astralagus, e.g. Astalagus sinicus (Chinese milkwetch), Thermopsis, e.g. Thermopsis luinoides (Goldenbanner) and alike.

The present invention also relates to mixtures wherein the at least one pesticide II is selected from Mesorhizobium huakuii and further comprises a compound III, wherein compound III is selected from jasmonic acid or salts or derivatives thereof including cis- jasmone, preferably methyl-jasmonate or cis-jasmone.

Suitable and commercially available M. huakuii strain is HN3015 which was isolated from Astralagus sinicus in a rice-growing field of Southern China (see e.g. World J. Microbiol. Biotechn. (2007) 23(6), 845-851 , ISSN 0959-3993).

The present invention also relates to mixtures, wherein the at least one pesticide II is selected from Azospirillum amazonense, A. brasilense, A. Iipoferum, A. irakense and A. halopraeferens, more preferably from A. brasilense, in particular selected from A.

brasilense strains BR 1 1005 (Sp245) and AZ39 which are both commercially used in Brazil and are obtainable from EMBRAPA-Agribiologia, Brazil. These mixtures are particularly suitable in soybean.

The present invention also relates to mixtures wherein the at least one pesticide II is selected from A. amazonense, A. brasilense, A. Iipoferum, A. irakense and A.

halopraeferens, more preferably A. brasilense, and further comprises a compound III, wherein compound III is selected from jasmonic acid or salts or derivatives thereof including cis-jasmone, preferably methyl-jasmonate or cis-jasmone.

The present invention also relates to mixtures wherein the at least one pesticide II is selected from Rhizobium leguminosarum bv. phaseoli, especially strain RG-B10 thereof; R. I. trifolii, especially strain RP1 13-7 thereof, R. I. bv. viciae, in particular strains SU303, WSM1455 and P1 NP3Cst thereof; R. tropici, especially strains CC51 1 , SEMIA 4077 and SEMIA 4080 thereof; and Sinorhizobium meliloti, especially strain MSDJ0848 thereof.

According to a further embodiment, in the inventive mixtures pesticide II is selected from one compound II selected from Sinorhizobium meliloti MSDJ0848, S. meliloti N RG 185, S. meliloti RR1128, S. meliloti S U277, Rhizobium leguminosarum bv.

phaseoli RG-B10, R. leguminosarum bv. viciae P1 NP3Cst, R. leguminosarum bv.

viciae RG-P2, R. leguminosarum bv. viciae SU303, R. leguminosarum bv. viciae

WSM1455, R. leguminosarum bv. trifolii RP1 13-7, R. leguminosarum bv. trifolii 095, R. leguminosarum bv. frifo/// TA1 , R. leguminosarum bv. trifolii CC283b, R.

leguminosarum bv. trifolii CB782, R. leguminosarum bv. trifolii CC1099, R.

leguminosarum bv. trifolii CC275e, R. leguminosarum bv. info// WSM 1325, R. tropici

CC51 1 , R. tropici SEMA 4077 and R. tropici SEMIA 4080.

Sinorhizobium meliloti is commercially available from Becker Underwood as product Dormal® Alfalfa & Luzerne. Rhizobium leguminosarum bv. phaseoli is commercially available from Becker Underwood as product Rhizo Stick. These strains are particulyrly suitable as inoculants for various legumes such as alfalfa, clover, peas, beans, lentils, soybeans, peanuts and others. Rhizobium leguminosarum bv. phaseoli, also called R. phaseoli and recently the type I isolates being re-classified as R. etli, is commercially available from Becker

Underwood, now BASF Corporation, USA, as product Rhizo-Stick for dry beans.

Particularly suitable strains especially for the legume common bean (Phaseolus vulgaris), but also for other crops such as corn and lettuce, are as follows: R.

leguminosarum bv. phaseoli RG-B10 (identical to strain USDA 9041 ) is commercially available as NODULATOR Dry Bean in Africa, HiStick NT Dry bean in US, and

NOUDLATOR Dry Bean in Canada from Becker Underwood, USA, now BASF

Corporation, USA and is known from Int. J. Syst. Bacteriol. 46(1 ), 240-244, 1996; Int. J. Syst. Evol. Microbiol. 50, 159-170, 2000.

Further R. I. bv. phaseoli or R. etli strains are e.g. known from the abovementioned refences and Appl. Environ. Microbiol. 45(3), 737-742, 1983; ibida 54(5), 1280-1283, 1988.

R. legominosarum bv. viciae P1 NP3Cst (also referred to as 1435) is known from New Phytol. 179(1 ), 224-235, 2008; and e.g. in NODULATOR PL Peat Granule from Becker Underwood, USA; or in NODULATOR XL PL from Becker Underwood, Canada). R. leguminosarum bv. viciae RG-P2 (also called P2) is commercially available as inoculant for pean and lentils as RhizUP peat in Canada from Becker Underwood, Canada now BASF Agricultural Specialties Ltd., Canada. R. leguminosarum bv. viciae WSM1455 is commercially available NODULAID for faba beans peat from Becker Underwood, Australia now BASF Agricultural Specialties Ltd., Australia. R.

leguminosarum bv. viciae SU303 is commercially available as NODULAID Group E, NODULAID NT peat or NODULATOR granules for peas from Becker Underwood, Australia now BASF Agricultural Specialties Ltd., Australia. R. leguminosarum bv. viciae WSM1455 is commercially available as NODULAID Group F peat, NODULAID NT and NODULATOR granules for faba bean from Becker Underwood, Australia, now BASF Agricultural Specialties, Australia, and is also as inoculant for faba beans as NODULATOR SA faba bean in Canada or as Faba Sterile Peat in Europe or as NODULATOR faba bean granules in Canada from Becker Underwood, Canada now BASF Agricultural Specialties Ltd., Canada.

Rhizobium leguminosarum bv. trifolii \s commercially available from Becker Underwood as product Nodulator or DORMAL true clover. Suitable strains are especially useful for all kind of clovers, are as follows: R. legominosarum bv. trifolii strains RP1 13-7 (also called 1 13-7) and 095 are commercially available from Becker Underwood, USA, now BASF Corporation, USA; see also Appl. Environ. Microbiol. 44(5), 1096-1 101 . Suitable strain R. legominosarum bv. fr/To//7 TA1 obtained from Australia is known from Appl. Environ. Microbiol. 49(1 ), 127-131 , 1985 and commercially available as NODULAID peat for white clover from Becker Underwood, Australia, now BASF Agricultural Specialties, Australia. R. leguminosarum bv. trifolii CC283b is commercially available as NODULAID peat for Caucasian clover from Becker Underwood, Australia, now BASF Agricultural Specialties, Australia. R. leguminosarum bv. trifolii CC1099 is commercially available as NODULAID peat for sainfoin from Becker Underwood, Australia, now BASF Agricultural Specialties, Australia. R. leguminosarum bv. trifolii CC275e is commercially available as NODULAID peat for NZ white clover from Becker Underwood, Australia, now BASF Agricultural Specialties, Australia. R. leguminosarum bv. trifolii CB782 is commercially available as NODULAID peat for Kenya white clover from Becker Underwood, Australia, now BASF Agricultural Specialties, Australia. R. legominosarum bv. trifolii strain WSM1325 has been collected in 1993 from the Greek Island of Serifos, is commercially available in NODULAID peat for sub clover and NODULATOR granules for sub clover both from Becker Underwood, Australia, now BASF Agricultural Specialties, Australia for a broad range of annual clovers of

Mediterranean origin, and is known from Stand. Genomic Sci. 2(3), 347-356, 2010. R. legominosarum bv. trifolii strain WSM2304 has been isolated from Trifolium

polymorphum in Uruguay in 1998 and is known from Stand. Genomic Sci. 2(1 ), 66-76, 2010, and is particularly suitable to nodulate its clover host in Uruguay.

R. tropici ls useful for a range of legume crops especially in tropical regions such as Brazil. Suitable strains are especially useful for all kind of clovers, are as follows: R. tropici strain SEMIA 4080 (identical to PRF 81 ; known from Soil Biology & Biochemistry 39, 867-876, 2007; BMC Microbiol. 12:84, 2012) is commercially available in

NITRAFIX FEIJAO peat for beans from BASF Agricultural Specialties, Brazil and has been used as commercial inoculant for applications to common bean crops in Brazil since 1998, and is deposited with FEPAGRO-Fundagao Estadual de Pesquisa

Agropecuaria, Rua Gongalves Dias, 570, Bairro Menino Deus, Porto Alegre/RS, Brazil. R. tropici is useful for a range of legume crops especially in tropical regions such as Brazil. Suitable strains are especially useful for all kind of clovers, are as follows: R. tropici strain SEMIA 4077 (identical to CIAT899; Rev. Ciena Agron. 44(4) Fortaleza Oct./Dec. 2013) is commercially available in NITRAFIX FEIJAO peat for beans from BASF Agricultural Specialties, Brazil. R. tropici strain CC51 1 is commercially available as NODULAID peat for common bean from Becker Underwood, Australia, now BASF Agricultural Speciealties, Australia, and is known from Agronomy, N.Z. 36, 4-35, 2006. The present invention also relates to mixtures wherein the at least one pesticide II is selected from R. leguminosarum bv. phaseoli, R. I. trifolii, R. I. bv. viciae, R. tropici and Sinorhizobium meliloti, and further comprises a compound III, wherein compound III is selected from jasmonic acid or salts or derivatives thereof including cis-jasmone, preferably methyl-jasmonate or cis-jasmone.

According to a further embodiment, the at least one pesticide II is selected from Delftia acidovorans, in particular strain RAY209, especially in soybean and canola.

According to a further embodiment, the at least one pesticide II is selected from

Lysobacter spp., preferably selected from L.antibioticus, in particular strains 13-1 and

HS124, preferably in rice or pepper for control of Phytophthora or bacterial leaf blight.

According to a further embodiment, the at least one pesticide II is selected from L. enzymogenes, in particular strain 3.1 T8.

According to a further embodiment, the at least one pesticide II is selected from

Lysobacter spp., preferably selected from Pseudomonas spp., in particular strain MA

342 and Pseudomonas sp. DSM 13134. According to a further embodiment, the at least one pesticide II is selected from Penicillium bilaiae.

Preference is also given to mixtures comprising as pesticide II (component 2) a biopesticide from group L6), preferably selected from abscisic acid, aluminium silicate (kaolin), humates, Ascophyllum nodosum (Norwegian kelp, Brown kelp) extract and Ecklonia maxima (kelp) extract.

Preference is also given to mixtures comprising as pesticide II a biopesticide selected from the isoflavones formonennitin, hesperetin and naringenin.

Accordingly, the present invention furthermore relates to compositions comprising one compound I (component 1 ) and one further pesticide II (component 2), which pesticide II is selected from the column "Co. 2" of the lines D-1 to D-830 of Table D.

A further embodiment relates to the compositions D-1 to D-830 listed in Table D, where a row of Table D corresponds in each case to a fungicidal composition comprising as active components one of the in the present specification individualized compounds of formula I (component 1 ) and the respective further pesticide II from groups A) to O) (component 2) stated in the row in question. Preferably, the compositions described comprise the active components in synergistically effective amounts.

Table D: Compositions comprising as active components one indiviualized compound I (I) (in column Co.1 ) and as component 2) (in column Co.2) one further pesticide II from groups A) to O) [which is coded e.g. as (A.1.1 ) for azoxystrobin as defned above].

Mixt. Co.1 Co. 2 Mixt. Co.1 Co. 2 Mixt. Co.1 Co. 2

D-1 (I) (A.1 .1 ) D-18 (I) (A.1 .18) D-35 (I) (A.3.7)

D-2 (I) (A.1 .2) D-19 (I) (A.1 .19) D-36 (I) (A.3.8)

D-3 (I) (A.1 .3) D-20 (I) (A.1 .20) D-37 (I) (A.3.9)

D-4 (I) (A.1 .4) D-21 (I) (A.1 .21 ) D-38 (I) (A.3.10)

D-5 (I) (A.1 .5) D-22 (I) (A.2.1 ) D-39 (I) (A.3.1 1 )

D-6 (I) (A.1 .6) D-23 (I) (A.2.2) D-40 (I) (A.3.12)

D-7 (I) (A.1 .7) D-24 (I) (A.2.3) D-41 (I) (A.3.13)

D-8 (I) (A.1 .8) D-25 (I) (A.2.4) D-42 (I) (A.3.14)

D-9 (I) (A.1 .9) D-26 (I) (A.2.5) D-43 (I) (A.3.15)

D-10 (I) (A.1 .10) D-27 (I) (A.2.6) D-44 (I) (A.3.16)

D-1 1 (I) (A.1 .1 1 ) D-28 (I) (A.2.7) D-45 (I) (A.3.17)

D-12 (I) (A.1 .12) D-29 (I) (A.3.1 ) D-46 (I) (A.3.18)

D-13 (I) (A.1 .13) D-30 (I) (A.3.2) D-47 (I) (A.3.19)

D-14 (I) (A.1 .14) D-31 (I) (A.3.3) D-48 (I) (A.3.20)

D-15 (I) (A.1 .15) D-32 (I) (A.3.4) D-49 (I) (A.3.21 )

D-16 (I) (A.1 .16) D-33 (I) (A.3.5) D-50 (I) (A.3.22)

D-17 (I) (A.1 .17) D-34 (I) (A.3.6) D-51 (I) (A.3.23) Mixt. Co.1 Co.2 Mixt. Co.1 Co.2 Mixt. Co.1 Co.2

D-52 (I) (A.3.24) D-93 (I) (B.1.26) D-134 (I) (C.2.1)

D-53 (I) (A.3.25) D-94 (I) (B.1.27) D-135 (I) (C.2.2)

D-54 (I) (A.3.26) D-95 (I) (B.1.28) D-136 (I) (C.2.3)

D-55 (I) (A.3.27) D-96 (I) (B.1.29) D-137 (I) (C.2.4)

D-56 (I) (A.4.1) D-97 (I) (B.1.30) D-138 (I) (C.2.5)

D-57 (I) (A.4.2) D-98 (I) (B.1.31) D-139 (I) (C.2.6)

D-58 (I) (A.4.3) D-99 (I) (B.1.32) D-140 (I) (C.2.7)

D-59 (I) (A.4.4) D-100 (I) (B.1.33) D-141 (I) (D.1.1)

D-60 (I) (A.4.5) D-101 (I) (B.1.34) D-142 (I) (D.1.2)

D-61 (I) (A.4.6) D-102 (I) (B.1.35) D-143 (I) (D.1.3)

D-62 (I) (A.4.7) D-103 (I) (B.1.36) D-144 (I) (D.1.4)

D-63 (I) (A.4.8) D-104 (I) (B.1.37) D-145 (I) (D.1.5)

D-64 (I) (A.4.9) D-105 (I) (B.1.38) D-146 (I) (D.1.6)

D-65 (I) (A.4.10) D-106 (I) (B.1.39) D-147 (I) (D.2.1)

D-66 (I) (A.4.11) D-107 (I) (B.1.40) D-148 (I) (D.2.2)

D-67 (I) (A.4.12) D-108 (I) (B.1.41) D-149 (I) (D.2.3)

D-68 (I) (B.1.1) D-109 (I) (B.1.42) D-150 (I) (D.2.4)

D-69 (I) (B.1.2) D-110 (I) (B.1.43) D-151 (I) (D.2.5)

D-70 (I) (B.1.3) D-111 (I) (B.1.44) D-152 (I) (D.2.6)

D-71 (I) (B.1.4) D-112 (I) (B.1.45) D-153 (I) (D.2.7)

D-72 (I) (B.1.5) D-113 (I) (B.1.46) D-154 (I) (E.1.1)

D-73 (I) (B.1.6) D-114 (I) (B.1.47) D-155 (I) (E.1.2)

D-74 (I) (B.1.7) D-115 (I) (B.1.48) D-156 (I) (E.1.3)

D-75 (I) (B.1.8) D-116 (I) (B.1.49) D-157 (I) (E.2.1)

D-76 (I) (B.1.9) D-117 (I) (B.1.50) D-158 (I) (E.2.2)

D-77 (I) (B.1.10) D-118 (I) (B.2.1) D-159 (I) (E.2.3)

D-78 (I) (B.1.11) D-119 (I) (B.2.2) D-160 (I) (E.2.4)

D-79 (I) (B.1.12) D-120 (I) (B.2.3) D-161 (I) (E.2.5)

D-80 (I) (B.1.13) D-121 (I) (B.2.4) D-162 (I) (E.2.6)

D-81 (I) (B.1.14) D-122 (I) (B.2.5) D-163 (I) (E.2.7)

D-82 (I) (B.1.15) D-123 (I) (B.2.6) D-164 (I) (E.2.8)

D-83 (I) (B.1.16) D-124 (I) (B.2.7) D-165 (I) (F.1.1)

D-84 (I) (B.1.17) D-125 (I) (B.2.8) D-166 (I) (F.1.2)

D-85 (I) (B.1.18) D-126 (I) (B.3.1) D-167 (I) (F.1.3)

D-86 (I) (B.1.19) D-127 (I) (C.1.1) D-168 (I) (F.1.4)

D-87 (I) (B.1.20) D-128 (I) (C.1.2) D-169 (I) (F.1.5)

D-88 (I) (B.1.21) D-129 (I) (C.1.3) D-170 (I) (F.1.6)

D-89 (I) (B.1.22) D-130 (I) (C.1.4) D-171 (I) (F.2.1)

D-90 (I) (B.1.23) D-131 (I) (C.1.5) D-172 (I) (G.1.1)

D-91 (I) (B.1.24) D-132 (I) (C.1.6) D-173 (I) (G.1.2)

D-92 (I) (B.1.25) D-133 (I) (C.1.7) D-174 (I) (G.1.3) Mixt. Co.1 Co.2 Mixt. Co.1 Co.2 Mixt. Co.1 Co.2

D-175 (I) (G.1.4) D-216 (I) (H.3.7) D-257 (I) (K.1.11)

D-176 (I) (G.2.1) D-217 (I) (H.3.8) D-258 (I) (K.1.12)

D-177 (I) (G.2.2) D-218 (I) (H.3.9) D-259 (I) (K.1.13)

D-178 (I) (G.2.3) D-219 (I) (H.3.10) D-260 (I) (K.1.14)

D-179 (I) (G.2.4) D-220 (I) (H.3.11) D-261 (I) (K.1.15)

D-180 (I) (G.2.5) D-221 (I) (H.4.1) D-262 (I) (K.1.16)

D-181 (I) (G.2.6) D-222 (I) (H.4.2) D-263 (I) (K.1.17)

D-182 (I) (G.2.7) D-223 (I) (H.4.3) D-264 (I) (K.1.18)

D-183 (I) (G.3.1) D-224 (I) (H.4.4) D-265 (I) (K.1.19)

D-184 (I) (G.3.2) D-225 (I) (H.4.5) D-266 (I) (K.1.20)

D-185 (I) (G.3.3) D-226 (I) (H.4.6) D-267 (I) (K.1.21)

D-186 (I) (G.3.4) D-227 (I) (H.4.7) D-268 (I) (K.1.22)

D-187 (I) (G.3.5) D-228 (I) (H.4.8) D-269 (I) (K.1.23)

D-188 (I) (G.3.6) D-229 (I) (H.4.9) D-270 (I) (K.1.24)

D-189 (I) (G.3.7) D-230 (I) (H.4.10) D-271 (I) (K.1.25)

D-190 (I) (G.3.8) D-231 (I) (1.1.1) D-272 (I) (K.1.26)

D-191 (I) (G.4.1) D-232 (I) (1.1.2) D-273 (I) (K.1.27)

D-192 (I) (G.5.1) D-233 (I) (1.2.1) D-274 (I) (K.1.28)

D-193 (I) (G.5.2) D-234 (I) (I.2.2) D-275 (I) (K.1.29)

D-194 (I) (G.5.3) D-235 (I) (I.2.3) D-276 (I) (K.1.30)

D-195 (I) (H.1.1) D-236 (I) (I.2.4) D-277 (I) (K.1.31)

D-196 (I) (H.1.2) D-237 (I) (I.2.5) D-278 (I) (K.1.32)

D-197 (I) (H.1.3) D-238 (I) (J.1.1) D-279 (I) (K.1.33)

D-198 (I) (H.1.4) D-239 (I) (J.1.2) D-280 (I) (K.1.34)

D-199 (I) (H.1.5) D-240 (I) (J.1.3) D-281 (I) (K.1.35)

D-200 (I) (H.1.6) D-241 (I) (J.1.4) D-282 (I) (K.1.36)

D-201 (I) (H.2.1) D-242 (I) (J.1.5) D-283 (I) (K.1.37)

D-202 (I) (H.2.2) D-243 (I) (J.1.6) D-284 (I) (K.1.38)

D-203 (I) (H.2.3) D-244 (I) (J.1.7) D-285 (I) (K.1.39)

D-204 (I) (H.2.4) D-245 (I) (J.1.8) D-286 (I) (K.1.40)

D-205 (I) (H.2.5) D-246 (I) (J.1.9) D-287 (I) (K.1.41)

D-206 (I) (H.2.6) D-247 (I) (K.1.1) D-288 (I) (K.1.42)

D-207 (I) (H.2.7) D-248 (I) (K.1.2) D-289 (I) (K.1.43)

D-208 (I) (H.2.8) D-249 (I) (K.1.3) D-290 (I) (K.1.44)

D-209 (I) (H.2.9) D-250 (I) (K.1.4) D-291 (I) (K.1.45)

D-210 (I) (H.3.1) D-251 (I) (K.1.5) D-292 (I) (K.1.46)

D-211 (I) (H.3.2) D-252 (I) (K.1.6) D-293 (I) (K.1.47)

D-212 (I) (H.3.3) D-253 (I) (K.1.7) D-294 (I) (M.1.1)

D-213 (I) (H.3.4) D-254 (I) (K.1.8) D-295 (I) (M.1.2)

D-214 (I) (H.3.5) D-255 (I) (K.1.9) D-296 (I) (M.1.3)

D-215 (I) (H.3.6) D-256 (I) (K.1.10) D-297 (I) (M.1.4) Mixt. Co.1 Co.2 Mixt. Co.1 Co.2 Mixt. Co.1 Co.2

D-298 (I) (M.1.5) D-339 (I) (M.1.46) D-380 (I) (N.13.3)

D-299 (I) (M.1.6) D-340 (I) (M.1.47) D-381 (I) (N.13.4)

D-300 (I) (M.1.7) D-341 (I) (M.1.48) D-382 (I) (N.13.5)

D-301 (I) (M.1.8) D-342 (I) (M.1.49) D-383 (I) (N.13.6)

D-302 (I) (M.1.9) D-343 (I) (M.1.50) D-384 (I) (N.13.7)

D-303 (I) (M.1.10) D-344 (I) (N.1.1) D-385 (I) (N.13.8)

D-304 (I) (M.1.11) D-345 (I) (N.1.2) D-386 (I) (N.13.9)

D-305 (I) (M.1.12) D-346 (I) (N.1.3) D-387 (I) (N.14.1)

D-306 (I) (M.1.13) D-347 (I) (N.1.4) D-388 (I) (N.14.2)

D-307 (I) (M.1.14) D-348 (I) (N.1.5) D-389 (I) (N.15.1)

D-308 (I) (M.1.15) D-349 (I) (N.2.1) D-390 (I) (N.16.1)

D-309 (I) (M.1.16) D-350 (I) (N.2.2) D-391 (I) (N.16.2)

D-310 (I) (M.1.17) D-351 (I) (N.2.3) D-392 (I) (N.17.1)

D-311 (I) (M.1.18) D-352 (I) (N.3.1) D-393 (I) (N.17.2)

D-312 (I) (M.1.19) D-353 (I) (N.3.2) D-394 (I) (N.17.3)

D-313 (I) (M.1.20) D-354 (I) (N.3.3) D-395 (I) (N.17.4)

D-314 (I) (M.1.21) D-355 (I) (N.3.4) D-396 (I) (N.17.5)

D-315 (I) (M.1.22) D-356 (I) (N.4.1) D-397 (I) (N.17.6)

D-316 (I) (M.1.23) D-357 (I) (N.5.1) D-398 (I) (N.17.7)

D-317 (I) (M.1.24) D-358 (I) (N.6.1) D-399 (I) (N.17.8)

D-318 (I) (M.1.25) D-359 (I) (N.6.2) D-400 (I) (N.17.9)

D-319 (I) (M.1.26) D-360 (I) (N.6.3) D-401 (I) (N.17.10)

D-320 (I) (M.1.27) D-361 (I) (N.6.4) D-402 (I) (N.17.11)

D-321 (I) (M.1.28) D-362 (I) (N.6.5) D-403 (I) (N.17.12)

D-322 (I) (M.1.29) D-363 (I) (N.7.1) D-404 (I) (0.1.1)

D-323 (I) (M.1.30) D-364 (I) (N.7.2) D-405 (I) (0.1.2)

D-324 (I) (M.1.31) D-365 (I) (N.7.3) D-406 (I) (0.1.3)

D-325 (I) (M.1.32) D-366 (I) (N.8.1) D-407 (I) (0.1.4)

D-326 (I) (M.1.33) D-367 (I) (N.9.1) D-408 (I) (0.1.5)

D-327 (I) (M.1.34) D-368 (I) (N.10.1) D-409 (I) (0.1.6)

D-328 (I) (M.1.35) D-369 (I) (N.10.2) D-410 (I) (0.1.7)

D-329 (I) (M.1.36) D-370 (I) (N.10.3) D-411 (I) (0.1.8)

D-330 (I) (M.1.37) D-371 (I) (N.10.4) D-412 (I) (0.1.9)

D-331 (I) (M.1.38) D-372 (I) (N.10.5) D-413 (I) (0.1.10)

D-332 (I) (M.1.39) D-373 (I) (N.11.1) D-414 (I) (0.1.11)

D-333 (I) (M.1.40) D-374 (I) (N.12.1) D-415 (I) (0.1.12)

D-334 (I) (M.1.41) D-375 (I) (N.12.2) D-416 (I) (0.1.13)

D-335 (I) (M.1.42) D-376 (I) (N.12.3) D-417 (I) (0.1.14)

D-336 (I) (M.1.43) D-377 (I) (N.12.4) D-418 (I) (0.1.15)

D-337 (I) (M.1.44) D-378 (I) (N.13.1) D-419 (I) (0.1.16)

D-338 (I) (M.1.45) D-379 (I) (N.13.2) D-420 (I) (0.1.17) Mixt. Co.1 Co.2 Mixt. Co.1 Co.2 Mixt. Co.1 Co.2

D-421 (I) (0.1.18) D-462 (I) (0.3.5) D-503 (I) (0.4.19)

D-422 (I) (0.1.19) D-463 (I) (0.3.6) D-504 (I) (O.4.20)

D-423 (I) (0.1.20) D-464 (I) (0.3.7) D-505 (I) (0.4.21)

D-424 (I) (0.1.21) D-465 (I) (0.3.8) D-506 (I) (0.4.22)

D-425 (I) (0.1.22) D-466 (I) (0.3.9) D-507 (I) (0.4.23)

D-426 (I) (0.1.23) D-467 (I) (0.3.10) D-508 (I) (0.4.24)

D-427 (I) (0.1.24) D-468 (I) (0.3.11) D-509 (I) (0.5.1)

D-428 (I) (0.1.25) D-469 (I) (0.3.12) D-510 (I) (0.5.2)

D-429 (I) (0.1.26) D-470 (I) (0.3.13) D-511 (I) (0.5.3)

D-430 (I) (0.1.27) D-471 (I) (0.3.14) D-512 (I) (0.5.4)

D-431 (I) (0.1.28) D-472 (I) (0.3.15) D-513 (I) (0.5.5)

D-432 (I) (0.1.29) D-473 (I) (0.3.16) D-514 (I) (0.5.6)

D-433 (I) (0.1.30) D-474 (I) (0.3.17) D-515 (I) (0.5.7)

D-434 (I) (0.1.31) D-475 (I) (0.3.18) D-516 (I) (0.5.8)

D-435 (I) (0.1.32) D-476 (I) (0.3.19) D-517 (I) (0.5.9)

D-436 (I) (0.1.33) D-477 (I) (O.3.20) D-518 (I) (0.6.1)

D-437 (I) (0.1.34) D-478 (I) (0.3.21) D-519 (I) (0.6.2)

D-438 (I) (0.1.35) D-479 (I) (0.3.22) D-520 (I) (0.6.3)

D-439 (I) (0.1.36) D-480 (I) (0.3.23) D-521 (I) (0.6.4)

D-440 (I) (0.1.37) D-481 (I) (0.3.24) D-522 (I) (0.6.5)

D-441 (I) (0.1.38) D-482 (I) (0.3.25) D-523 (I) (0.6.6)

D-442 (I) (0.2.1) D-483 (I) (0.3.26) D-524 (I) (0.6.7)

D-443 (I) (0.2.2) D-484 (I) (0.3.27) D-525 (I) (0.7.1)

D-444 (I) (0.2.3) D-485 (I) (0.4.1) D-526 (I) (0.7.2)

D-445 (I) (0.2.4) D-486 (I) (0.4.2) D-527 (I) (0.7.3)

D-446 (I) (0.2.5) D-487 (I) (0.4.3) D-528 (I) (0.7.4)

D-447 (I) (0.2.6) D-488 (I) (0.4.4) D-529 (I) (0.7.5)

D-448 (I) (0.2.7) D-489 (I) (0.4.5) D-530 (I) (0.7.6)

D-449 (I) (0.2.8) D-490 (I) (0.4.6) D-531 (I) (0.8.1)

D-450 (I) (0.2.9) D-491 (I) (0.4.7) D-532 (I) (0.8.2)

D-451 (I) (0.2.10) D-492 (I) (0.4.8) D-533 (I) (0.8.3)

D-452 (I) (0.2.11) D-493 (I) (0.4.9) D-534 (I) (0.8.4)

D-453 (I) (0.2.12) D-494 (I) (0.4.10) D-535 (I) (0.8.5)

D-454 (I) (0.2.13) D-495 (I) (0.4.11) D-536 (I) (0.9.1)

D-455 (I) (0.2.14) D-496 (I) (0.4.12) D-537 (I) (0.9.2)

D-456 (I) (0.2.15) D-497 (I) (0.4.13) D-538 (I) (0.9.3)

D-457 (I) (0.2.16) D-498 (I) (0.4.14) D-539 (I) (O.10.1)

D-458 (I) (0.3.1) D-499 (I) (0.4.15) D-540 (I) (0.11.1)

D-459 (I) (0.3.2) D-500 (I) (0.4.16) D-541 (I) (0.11.2)

D-460 (I) (0.3.3) D-501 (I) (0.4.17) D-542 (I) (0.11.3)

D-461 (I) (0.3.4) D-502 (I) (0.4.18) D-543 (I) (0.11.4) Mixt. Co.1 Co.2 Mixt. Co.1 Co.2 Mixt. Co.1 Co.2

D-544 (I) (0.12.1) D-585 (I) (L.1.21) D-626 (I) (L.1.62)

D-545 (I) (0.13.1) D-586 (I) (L.1.22) D-627 (I) (L.1.63)

D-546 (I) (0.14.1) D-587 (I) (L.1.23) D-628 (I) (L.1.64)

D-547 (I) (0.14.2) D-588 (I) (L.1.24) D-629 (I) (L.1.65)

D-548 (I) (0.15.1) D-589 (I) (L.1.25) D-630 (I) (L.1.66)

D-549 (I) (0.15.2) D-590 (I) (L.1.26) D-631 (I) (L.1.67)

D-550 (I) (0.15.3) D-591 (I) (L.1.27) D-632 (I) (L.1.68)

D-551 (I) (0.15.4) D-592 (I) (L.1.28) D-633 (I) (L.1.69)

D-552 (I) (0.15.5) D-593 (I) (L.1.29) D-634 (I) (L.1.70)

D-553 (I) (0.15.6) D-594 (I) (L.1.30) D-635 (I) (L.1.71)

D-554 (I) (0.15.7) D-595 (I) (L.1.31) D-636 (I) (L.1.72)

D-555 (I) (0.15.8) D-596 (I) (L.1.32) D-637 (I) (L.1.73)

D-556 (I) (0.15.9) D-597 (I) (L.1.33) D-638 (I) (L.2.1)

D-557 (I) (O.15.10) D-598 (I) (L.1.34) D-639 (I) (L.2.2)

D-558 (I) (0.15.11) D-599 (I) (L.1.35) D-640 (I) (L.2.3)

D-559 (I) (0.16.1) D-600 (I) (L.1.36) D-641 (I) (L.2.4)

D-560 (I) (0.16.2) D-601 (I) (L.1.37) D-642 (I) (L.2.5)

D-561 (I) (0.16.3) D-602 (I) (L.1.38) D-643 (I) (L.2.6)

D-562 (I) (0.16.4) D-603 (I) (L.1.39) D-644 (I) (L.2.7)

D-563 (I) (0.16.5) D-604 (I) (L.1.40) D-645 (I) (L.2.8)

D-564 (I) (0.16.6) D-605 (I) (L.1.41) D-646 (I) (L.2.9)

D-565 (I) (L.1.1) D-606 (I) (L.1.42) D-647 (I) (L.2.10)

D-566 (I) (L.1.2) D-607 (I) (L.1.43) D-648 (I) (L.2.11)

D-567 (I) (L.1.3) D-608 (I) (L.1.44) D-649 (I) (L.3.1)

D-568 (I) (L.1.4) D-609 (I) (L.1.45) D-650 (I) (L.3.2)

D-569 (I) (L.1.5) D-610 (I) (L.1.46) D-651 (I) (L.3.3)

D-570 (I) (L.1.6) D-611 (I) (L.1.47) D-652 (I) (L.3.4)

D-571 (I) (L.1.7) D-612 (I) (L.1.48) D-653 (I) (L.3.5)

D-572 (I) (L.1.8) D-613 (I) (L.1.49) D-654 (I) (L.3.6)

D-573 (I) (L.1.9) D-614 (I) (L.1.50) D-655 (I) (L.3.7)

D-574 (I) (L.1.10) D-615 (I) (L.1.51) D-656 (I) (L.3.8)

D-575 (I) (L.1.11) D-616 (I) (L.1.52) D-657 (I) (L.3.9)

D-576 (I) (L.1.12) D-617 (I) (L.1.53) D-658 (I) (L.3.10)

D-577 (I) (L.1.13) D-618 (I) (L.1.54) D-659 (I) (L.3.11)

D-578 (I) (L.1.14) D-619 (I) (L.1.55) D-660 (I) (L.3.12)

D-579 (I) (L.1.15) D-620 (I) (L.1.56) D-661 (I) (L.3.13)

D-580 (I) (L.1.16) D-621 (I) (L.1.57) D-662 (I) (L.3.14)

D-581 (I) (L.1.17) D-622 (I) (L.1.58) D-663 (I) (L.3.15)

D-582 (I) (L.1.18) D-623 (I) (L.1.59) D-664 (I) (L.3.16)

D-583 (I) (L.1.19) D-624 (I) (L.1.60) D-665 (I) (L.3.17)

D-584 (I) (L.1.20) D-625 (I) (L.1.61) D-666 (I) (L.3.18) Mixt. Co.1 Co. 2 Mixt. Co.1 Co. 2 Mixt. Co.1 Co. 2

D-667 (I) (L.3.19) D-708 (I) (L.4.5) D-749 (I) (L.5.13)

D-668 (I) (L.3.20) D-709 (I) (L.4.6) D-750 (I) (L.5.14)

D-669 (I) (L.3.21 ) D-710 (I) (L.4.7) D-751 (I) (L.5.15)

D-670 (I) (L.3.22) D-71 1 (I) (L.4.8) D-752 (I) (L.5.16)

D-671 (I) (L.3.23) D-712 (I) (L.4.9) D-753 (I) (L.5.17)

D-672 (I) (L.3.24) D-713 (I) (L.4.10) D-754 (I) (L.5.18)

D-673 (I) (L.3.25) D-714 (I) (L.4.1 1 ) D-755 (I) (L.5.19)

D-674 (I) (L.3.26) D-715 (I) (L.4.12) D-756 (I) (L.5.20)

D-675 (I) (L.3.27) D-716 (I) (L.4.13) D-757 (I) (L.5.21 )

D-676 (I) (L.3.28) D-717 (I) (L.4.14) D-758 (I) (L.5.22)

D-677 (I) (L.3.29) D-718 (I) (L.4.15) D-759 (I) (L.5.23)

D-678 (I) (L.3.30) D-719 (I) (L.4.16) D-760 (I) (L.5.24)

D-679 (I) (L.3.31 ) D-720 (I) (L.4.17) D-761 (I) (L.5.25)

D-680 (I) (L.3.32) D-721 (I) (L.4.18) D-762 (I) (L.5.26)

D-681 (I) (L.3.33) D-722 (I) (L.4.19) D-763 (I) (L.5.27)

D-682 (I) (L.3.34) D-723 (I) (L.4.20) D-764 (I) (L.5.28)

D-683 (I) (L.3.35) D-724 (I) (L.4.21 ) D-765 (I) (L.5.29)

D-684 (I) (L.3.36) D-725 (I) (L.4.22) D-766 (I) (L.5.30)

D-685 (I) (L.3.37) D-726 (I) (L.4.23) D-767 (I) (L.5.31 )

D-686 (I) (L.3.38) D-727 (I) (L.4.24) D-768 (I) (L.5.32)

D-687 (I) (L.3.39) D-728 (I) (L.4.25) D-769 (I) (L.5.33)

D-688 (I) (L.3.40) D-729 (I) (L.4.26) D-770 (I) (L.5.34)

D-689 (I) (L.3.41 ) D-730 (I) (L.4.27) D-771 (I) (L.5.35)

D-690 (I) (L.3.42) D-731 (I) (L.4.28) D-772 (I) (L.5.36)

D-691 (I) (L.3.43) D-732 (I) (L.4.29) D-773 (I) (L.5.37)

D-692 (I) (L.3.44) D-733 (I) (L.4.30) D-774 (I) (L.5.38)

D-693 (I) (L.3.45) D-734 (I) (L.4.31 ) D-775 (I) (L.5.39)

D-694 (I) (L.3.46) D-735 (I) (L.4.32) D-776 (I) (L.5.40)

D-695 (I) (L.3.47) D-736 (I) (L.4.33) D-777 (I) (L.5.41 )

D-696 (I) (L.3.48) D-737 (I) (L.5.1 ) D-778 (I) (L.5.42)

D-697 (I) (L.3.49) D-738 (I) (L.5.2) D-779 (I) (L.5.43)

D-698 (I) (L.3.50) D-739 (I) (L.5.3) D-780 (I) (L.5.44)

D-699 (I) (L.3.51 ) D-740 (I) (L.5.4) D-781 (I) (L.5.45)

D-700 (I) (L.3.52) D-741 (I) (L.5.5) D-782 (I) (L.5.46)

D-701 (I) (L.3.53) D-742 (I) (L.5.6) D-783 (I) (L.5.47)

D-702 (I) (L.3.54) D-743 (I) (L.5.7) D-784 (I) (L.5.48)

D-703 (I) (L.3.55) D-744 (I) (L.5.8) D-785 (I) (L.5.49)

D-704 (I) (L.4.1 ) D-745 (I) (L.5.9) D-786 (I) (L.5.50)

D-705 (I) (L.4.2) D-746 (I) (L.5.10) D-787 (I) (L.5.51 )

D-706 (I) (L.4.3) D-747 (I) (L.5.1 1 ) D-788 (I) (L.5.52)

D-707 (I) (L.4.4) D-748 (I) (L.5.12) D-789 (I) (L.5.53) Mixt. Co.1 Co. 2 Mixt. Co.1 Co. 2 Mixt. Co.1 Co. 2

D-790 (I) (L.5.54) D-804 (I) (L.5.64) D-818 (I) (L.6.4)

D-791 (I) (L.5.55) D-805 (I) (L.5.65) D-819 (I) (L.6.5)

D-792 (I) (L.5.56) D-806 (I) (L.5.66) D-820 (I) (L.6.6)

D-793 (I) (L.5.57) D-807 (I) (L.5.67) D-821 (I) (L.6.7)

D-794 (I) (L.5.58) D-808 (I) (L.5.67) D-822 (I) (L.6.8)

D-795 (I) (L.5.59) D-809 (I) (L.5.67) D-823 (I) (L.6.9)

D-796 (I) (L.5.60) D-810 (I) (L.5.68) D-824 (I) (L.6.10)

D-797 (I) (L.5.60) D-81 1 (I) (L.5.69) D-825 (I) (L.6.1 1 )

D-798 (I) (L.5.60) D-812 (I) (L.5.70) D-826 (I) (L.6.12)

D-799 (I) (L.5.60) D-813 (I) (L.5.71 ) D-827 (I) (L.6.13)

D-800 (I) (L.5.60) D-814 (I) (L.5.72) D-828 (I) (L.6.14)

D-801 (I) (L.5.61 ) D-815 (I) (L.6.1 ) D-829 (I) (L.6.15)

D-802 (I) (L.5.62) D-816 (I) (L.6.2) D-830 (I) (L.6.16)

D-803 (I) (L.5.63) D-817 (I) (L.6.3)

The active substances referred to as component 2, their preparation and their activity e.g. against harmful fungi is known (cf.: http://www.alanwood.net/pesticides/); these substances are commercially available. The compounds described by lUPAC nomenclature, their preparation and their fungicidal activity are also known (cf. Can. J.

Plant Sci. 48(6), 587-94, 1968; EP-A 141 317; EP-A 152 031 ; EP-A 226 917;

EP-A 243 970; EP-A 256 503; EP-A 428 941 ; EP-A 532 022; EP-A 1 028 125; EP-A

1 035 122; EP-A 1 201 648; EP-A 1 122 244, JP 2002316902; DE 19650197;

DE 10021412; DE 102005009458; US 3,296,272; US 3,325,503; WO 98/46608;

WO 99/14187; WO 99/24413; WO 99/27783; WO 00/29404; WO 00/46148;

WO 00/65913; WO 01/54501 ; WO 01/56358; WO 02/22583; WO 02/40431 ;

WO 03/10149; WO 03/1 1853; WO 03/14103; WO 03/16286; WO 03/53145;

WO 03/61388; WO 03/66609; WO 03/74491 ; WO 04/49804; WO 04/83193;

WO 05/120234; WO 05/123689; WO 05/123690; WO 05/63721 ; WO 05/87772;

WO 05/87773; WO 06/15866; WO 06/87325; WO 06/87343; WO 07/82098;

WO 07/90624, WO 1 1/028657, WO2012/168188, WO 2007/006670, WO 201 1/77514;

W013/047749, WO 10/069882, WO 13/047441 , WO 03/16303, WO 09/90181 ,

WO 13/007767, WO 13/010862, WO 13/127704, WO 13/024009 and WO 13/024010.

The mixtures of active substances can be prepared as compositions comprising besides the active ingredients at least one inert ingredient (auxiliary) by usual means, e. g. by the means given for the compositions of compounds I.

Concerning usual ingredients of such compositions reference is made to the explanations given for the compositions containing compounds I.

The mixtures of active substances according to the present invention are suitable as fungicides, as are the compounds of formula I. They are distinguished by an outstanding effectiveness against a broad spectrum of phytopathogenic fungi, especially from the classes of the Ascomycetes, Basidiomycetes, Deuteromycetes and Peronosporomycetes (syn. Oomycetes). In addition, it is refered to the explanations regarding the fungicidal activity of the compounds and the compositions containing compounds I, respectively.

According to one embodiment, the microbial pesticides selected from groups L1 ), L3) and L5) embrace not only the isolated, pure cultures of the respective micro-organism as defined herein, but also its cell-free extract, its suspensions in a whole broth culture or as a metabolite-containing supernatant or a purified metabolite obtained from a whole broth culture of the microorganism or microorganism strain.

According to a further embodiment, the microbial pesticides selected from groups L1 ), L3 and L5) embraces not only the isolated, pure cultures of the respective micro- organism as defined herein, but also a cell-free extract thereof or at least one metabolite thereof, and/or a mutant of the respective micro-organism having all the identifying characteristics thereof and also a cell-free extract or at least one metabolite of the mutant.

"Whole broth culture" refers to a liquid culture containing both cells and media.

"Supernatant" refers to the liquid broth remaining when cells grown in broth are removed by centrifugation, filtration, sedimentation, or other means well known in the art.

The term "cell-free extract" refers to an extract of the vegetative cells, spores and/or the whole culture broth of a microorganism comprising cellular metabolites produced by the respective microorganism obtainable by cell disruption methods known in the art such as solvent-based (e.g. organic solvents such as alcohols sometimesin

combination with suitable salts), temperature-based, application of shear forces, cell disrupotion with an ultrasonicator. The desired extract may be concentrated by conventional concentration techniques such as drying, evaporation, centrifugation or alike. Certain washing steps using organic solents and/or water-based media may also be applied to the crude extract preferably prior to use.

The term "metabolite" refers to any compound, substance or byproduct produced by a microorganism (such as fungi and bacteria) that has improves plant growth, water use efficiency of the plant, plant health, plant appearance, or the population of beneficial microorganisms in the soil around the plant activity.

The term "mutant" refers a microorganism obtained by direct mutant selection but also includes microorganisms that have been further mutagenized or otherwise manipulated (e.g., via the introduction of a plasmid). Accordingly, embodiments include mutants, variants, and or derivatives of the respective microorganism, both naturally occurring and artificially induced mutants. For example, mutants may be induced by subjecting the microorganism to known mutagens, such as N-methyl-nitrosoguanidine, using conventional methods.

Suitable bactericides are bronopol and isothiazolinone derivatives such as alkyliso- thiazolinones and benzisothiazolinones. Suitable anti-freezing agents are ethylene glycol, propylene glycol, urea and glycerin. Suitable anti-foaming agents are silicones, long chain alcohols, and salts of fatty acids. Suitable colorants (e.g. in red, blue, or green) are pigments of low water solubility and water-soluble dyes. Examples are inorganic colorants (e.g. iron oxide, titan oxide, iron hexacyanoferrate) and organic colorants (e.g. alizarin-, azo- and phthalocyanine colorants). Suitable tackifiers or binders are polyvinylpyrrolidons, polyvinylacetates, polyvinyl alcohols, polyacrylates, biological or synthetic waxes, and cellulose ethers.

In the case of mixtures comprising microbial pesticides II selected from groups L1 ), L3) and L5), the microorganisms as used according to the invention can be cultivated continuously or discontinuously in the batch process or in the fed batch or repeated fed batch process. A review of known methods of cultivation will be found in the textbook by Chmiel (Bioprozesstechnik 1. Einfuhrung in die Bioverfahrenstechnik (Gustav Fischer Verlag, Stuttgart, 1991 )) or in the textbook by Storhas (Bioreaktoren und periphere Einrichtungen (Vieweg Verlag, Braunschweig/Wiesbaden, 1994)).

When living microorganisms, such as pesticides II from groups L1 ), L3) and L5), form part of the compositions, such compositions can be prepared as compositions comprising besides the active ingredients at least one auxiliary (inert ingredient) by usual means (see e.g. H.D. Burges: Formulation of Micobial Biopestcides, Springer, 1998). Suitable customary types of such compositions are suspensions, dusts, powders, pastes, granules, pressings, capsules, and mixtures thereof. Examples for composition types are suspensions (e.g. SC, OD, FS), capsules (e.g. CS, ZC), pastes, pastilles, wettable powders or dusts (e.g. WP, SP, WS, DP, DS), pressings (e.g. BR, TB, DT), granules (e.g. WG, SG, GR, FG, GG, MG), insecticidal articles (e.g. LN), as well as gel formulations for the treatment of plant propagation materials such as seeds (e.g. GF). Herein, it has to be taken into account that each formulation type or choice of auxiliary should not influence the viability of the microorganism during storage of thecomposition and when finally applied to the soil, plant or plant propagation material. Suitable formulations are e.g. mentioned in WO 2008/002371 , US 6955,912, US 5,422,107.

Examples for suitable auxiliaries are those mentioned earlier herein, wherein it must be taken care that choice and amounts of such auxiliaries should not influence the viability of the microbial pesticides in the composition. Especially for bactericides and solvents, compatibility with the respective microorganism of the respective microbial pesticide has to be taken into account. In addition, compositions with microbial pesticides may further contain stabilizers or nutrients and UV protectants. Suitable stabilzers or nutrients are e.g. alpha-tocopherol, trehalose, glutamate, potassium sorbate, various sugars like glucose, sucrose, lactose and maltodextrine (H.D. Burges: Formulation of Micobial Biopestcides, Springer, 1998). Suitable UV protectants are e.g. inorganic compouns like titan dioxide, zinc oxide and iron oxide pigments or organic compounds like benzophenones, benzotriazoles and phenyltriazines. The compositions may in addition to auxiliaries mentioned for compositions comprising compounds I herein optionally comprise 0.1 - 80% stabilizers or nutrients and 0.1 -10% UV protectants. When mixtures comprising microbial pesticides are employed in crop protection, the application rates preferably range from about 1 x 10⁶ to 5 x 10¹⁵ (or more) CFU/ha. Preferably, the spore concentration is about 1 x 10⁷ to about 1 x 10¹¹ CFU/ha. In the case of (entomopathogenic) nematodes as microbial pesticides (e.g. Steinernema feltiae), the application rates preferably range inform about 1 x 10⁵ to 1 x 10¹² (or more), more preferably from 1 x 10⁸ to 1 x 10¹¹, even more preferably from 5 x 10⁸ to 1 x 10¹⁰ individuals (e.g. in the form of eggs, juvenile or any other live stages, preferably in an infetive juvenile stage) per ha.

When mixtures comprising microbial pesticides are employed in seed treatment, the application rates with respect to plant propagation material preferably range from about 1 x 10⁶ to 1 x 10¹² (or more) CFU/seed. Preferably, the concentration is about 1 x 10⁶ to about 1 x 10¹¹ CFU/seed. In the case of the microbial pesticides II, the application rates with respect to plant propagation material also preferably range from about 1 x 10⁷ to 1 x 10¹⁴ (or more) CFU per 100 kg of seed, preferably from 1 x 10⁹ to about 1 x 10¹¹ CFU per 100 kg of seed.

I. Synthesis examples With due modification of the starting compounds, the procedures shown in the synthesis example below can be used to obtain further compounds I. 1 -(4- chlorophenyl)-2-cyclopropyl-propan-1 -one was obtained according to procedures described in DE 3406993, EP 321409 and CN 101565406. Example 1 : Preparation of 2-(4-chlorophenyl)-2-(1-cyclopropylethyl)-3-methyl-oxirane

(A)

A solution of 1 ,1 -dibromoethane (6.2 g, 0.03 mol in 200 mL THF) was cooled to -78°C. Simultaneously 1 -(4-chlorophenyl)-2-cyclopropyl-propan-1 -one (3.5 g, 0.016 mol in 20 mL THF) and n-buthyl lithium (13.5 mL, 0.03 mol, in hexanes) were added dropwise at -78°C to the solution of 1 ,1 -dibromoethane within 15 minutes. The solution was then warmed to room temperature and stirred overnight. After addition of a saturated solution of ammonium chloride (200 mL) the mixture was extracted with methyl tert- butyl ether (two times, 100 mL). The combined organic phases were washed with a saturated aqueous solution of sodium chloride, dried over sodium sulfate and concentrated. The resulting crude material was purified by means of column

chromatography, which yielded compound A (3.0 g, 73%). ¹H-NMR (CDCI₃ 400 MHz): δ = 7.39 (m, 2H), 7.31 (m, 2H), 3.06 (m, 1 H), 1.41 (s, 3H), 0.99 (s, 3H), 1.05 (m, 1 H), 0.50 (m, 3H), 0.13-0.29 (m, 2H ).

Example 2: Preparation of 3-(4-chlorophenyl)-2-cyclopropyl-4-(1 ,2,4-triazol-1 -yl)pentan- 3-ol (B)

To a mixture of A (1 .2 g, 5.0 mmol) and 1 ,2,4-trizole (0.52 g, 7.6 mmol) in N,N- dimethylformamide (50 mL) was added cesium carbonate (2.0 g, 10.0 mmol) and heated to 160°C for 4h using microwave irraditation. After cooling to room temperature, water (100 mL) was added to the reaction mixture and extracted with ethyl acetate (two times, 100 mL). The combined organic phases were washed with a saturated aqueous solution of sodium chloride (50 mL), dried over sodium sulfate and concentrated. The resulting material was purified by means of column chromatography, which afforded compound B (400 mg, 26%).¹H-NMR (CDCI₃, 400 MHz): δ = 8.13 (1 H), 7.98 (1 H), 7.16- 7.69 (4H), 5.46 (1 H), 4.69-4.73 (1 H), 1.35 (3H), 1 .05 (1 H), 0.85 (3H), 0.35-0.44 (3H ), 0.10-0.19 (2H ).

II. Examples of the action against harmful fungi The fungicidal action of the compounds of the formula I was demonstrated by the following experiments:

11.1 Greenhouse tests The spray solutions were prepared in several steps: The stock solution were prepared: a mixture of acetone and/or dimethylsulfoxide and the wetting agent/emulsifier Wettol, which is based on ethoxylated alkylphenoles, in a relation (volume) solvent : emulsifier of 99 : 1 was added to 25 mg of the compound to give a total of 5 ml. Water was then added to a total volume of 100 ml. This stock solution was further diluted with the described solvent-emulsifier-water mixture to the given concentration.

Use example 1 : Protective control of soy bean rust on soy beans caused by

Phakopsora pachyrhizi (Phakpa P1 ) Leaves of pot-grown soy bean seedlings were sprayed to run-off with an aqueous suspension, containing the concentration of active ingredient as described below. The plants were allowed to air-dry. The trial plants were cultivated for 1 day in a

greenhouse chamber at 23-27°C and a relative humidity between 60 and 80%. Then the plants were inoculated with spores of Phakopsora pachyrhizi. To ensure the success the artificial inoculation, the plants were transferred to a humid chamber with a relative humidity of about 95 % and 20 to 24°C for 24 h. The trial plants were cultivated for fourteen days in a greenhouse chamber at 23-27°C and a relative humidity between 60 and 80%. The extent of fungal attack on the leaves was visually assessed as % diseased leaf area. In this test, the plants which had been treated with 150 ppm of the active substance B showed an infection of 1 % whereas the untreated plants were 90% infected. Use example 2. Preventative control of leaf blotch on wheat caused by Septoria tritici (Septtr P1 )

Leaves of pot-grown wheat seedling were sprayed to run-off with an aqueous suspension of the active compound, prepared as described. The plants were allowed to air-dry. At the following day the plants were inoculated with an aqueous spore suspension of Septoria tritici. Then the trial plants were immediately transferred to a humid chamber at 18-22°C and a relative humidity close to 100%. After 4 days the plants were transferred to a chamber with 18-22°C and a relative humidity close to 70%. After 4 weeks the extent of fungal attack on the leaves was visually assessed as % diseased leaf area.

In this test, the plants which had been treated with 150 ppm of the active substance B showed an infection of 1 % whereas the untreated plants were 90% infected. Use example 3: Preventative control of brown rust on wheat caused by Puccinia recondita (Puccrt P1 )

The first two developed leaves of pot-grown wheat seedling were sprayed to run-off with an aqueous suspension, containing the concentration of active ingredient as described below. The next day the plants were inoculated with spores of Puccinia recondita. To ensure the success the artificial inoculation, the plants were transferred to a humid chamber without light and a relative humidity of 95 to 99% and 20 to 24°C for 24 h. Then the trial plants were cultivated for 6 days in a greenhouse chamber at 20-24°C and a relative humidity between 65 and 70%. The extent of fungal attack on the leaves was visually assessed as % diseased leaf area.

In this test, the plants which had been treated with 150 ppm of the active substance B showed an infection of 15% whereas the untreated plants were 90% infected. Use example 4: Preventative fungicidal control of Botrytis cinerea on leaves of green pepper (Botrci P1 )

Young seedlings of green pepper were grown in pots to the 4 to 5 leaf stage. These plants were sprayed to run-off with an aqueous suspension, containing the

concentration of active ingredient as described below. The next day the plants were inoculated with an aqueous biomalt solution containing the spore suspension of Botrytis cinerea. Then the plants were immediately transferred to a humid chamber. After 5 days at 22 to 24°C and a relative humidity close to 100% the extent of fungal attack on the leaves was visually assessed as % diseased leaf area.

In this test, the plants which had been treated with 150 ppm of the active substance B showed an infection of 7% whereas the untreated plants were 100% infected.

Claims

claim:

Compounds of formula I

is N or CH; is hydrogen, halogen or SR^D; wherein

R^D is hydrogen, CN, Ci-C₆-alkyl, Ci-C₆-haloalkyl, C₂-C₆-alkenyl,

C2-C6-haloalkenyl, C2-C6-alkynyl or C2-C6-haloalkynyl; is halogen, CN, N0₂, OH, SH, Ci-C₆-alkyl, Ci-C₆-alkoxy, Ci-C₆-alkylthio, Ci-C6-alkylsulfinyl, Ci-C6-alkylsulfonyl, C2-C6-alkenyl, C2-C6-alkynyl, C₃-Cs- cycloalkyl, C₃-C8-cycloalkoxy, C3-C8-cycloalkyl-Ci-C4-alkyl, NH₂, NH(Ci-C₄- alkyl), N(Ci-C₄-alkyl)₂, NH(C₃-C₆-cycloalkyl), N(C₃-C₆-cycloalkyl)₂,

C(=0)-Ci-C₄-alkyl, C(=0)OH, C(=0)-0-Ci-C₄-alkyl, C(=0)-NH(Ci-C₄-alkyl), C(=0)-N(Ci-C₄-alkyl)₂, C(=0)-NH(C₃-C6-cycloalkyl), C(=0)-N(C₃-C₆- cycloalkyl)2, phenyl, heteroaryl, phenyl-Ci-C₄-alkyl or heteroaryl-Ci-C₄-alkyl, wherein the heteroaryl radical in the last-mentioned groups is 5- or 6- membered; and wherein the aliphatic, alicyclic and aromatic moieties of R¹ are unsubstituted or substituted by one, two, three or four or up to the maximum possible number of independently selected substituents R^1a; wherein

R^1a is halogen, CN, N0₂, OH, SH, NH₂, Ci-C₆-alkyl, Ci-C₆-haloalkyl, Ci-C6-alkoxy, Ci-C6-haloalkoxy, Ci-C6-alkylthio, Ci-C6-haloalkylthio, C₃-C8-cycloalkyl or Ci-C₄-alkoxy-Ci-C₄-alkyl; is hydrogen, halogen, CN, NO2, OH, SH, d-Ce-alkyl, d-Ce-alkoxy, C-i-Ce- alkylthio, Ci-C6-alkylsulfinyl, Ci-C6-alkylsulfonyl, C2-C6-alkenyl, C2-C6- alkynyl, C₃-C8-cycloalkyl, C₃-C8-cycloalkyloxycycloalkoxy, NH2, NH(Ci-C₄- alkyl), N(Ci-C₄-alkyl)₂, NH(C₃-C₆-cycloalkyl), N(C₃-C₆-cycloalkyl)₂,

C(=0)-Ci-C₄-alkyl, C(=0)OH, C(=0)-0-Ci-C₄-alkyl, C(=0)-NH(Ci-C₄-alkyl), C(=0)-N(Ci-C₄-alkyl)₂, C(=0)-NH(C₃-C₆-cycloalkyl), C(=0)-N(C₃-C₆- cycloalkyl)2, phenyl, heteroaryl, phenyl-Ci-C₄-alkyl or heteroaryl-Ci-C₄-alkyl, wherein the heteroaryl group in the last-mentioned groups is 5- or 6- membered; and wherein the aliphatic, alicyclic and aromatic moieties of R² are unsubstituted or substituted by one, two, three or four or up to the maximum possible number of independently selected substituents R^2a; wherein

R^2a is halogen, CN, N0₂, OH, SH, NH₂, Ci-C₆-alkyl, Ci-C₆-haloalkyl, Ci-C6-alkoxy, Ci-C6-haloalkoxy, Ci-C6-alkylthio, Ci-C6-haloalkylthio, C3-C8-cycloalkyl or Ci-C4-alkoxy-Ci-C4-alkyl; or R¹ and R² together with the carbon atom to which they are bound

(denominated as C*) form a vinyl group C*=CR¹¹ R²², wherein

R¹¹ and R²² are independently selected from the group consisting of hydrogen, halogen, CN, N0₂, OH, SH, NH₂, Ci-C₆-alkyl, Ci-C6-haloalkyl, Ci-C6-alkoxy, Ci-C6-haloalkoxy, Ci-C6-alkylthio, Ci-C6-haloalkylthio and Ci-C4-alkoxy-Ci-C4-alkyl; or R¹ and R² together with the carbon atom to which they are bound form a saturated or partially unsaturated three-, four-, five-, six- or seven-membered carbocycle or a saturated or partially unsaturated three-, four-, five-, six- or seven-membered heterocycle, wherein the heterocycle includes beside carbon atoms one, two, three or four heteroatoms independently selected from the group consisting of N , O and S, and wherein the carbo- and heterocycle are

unsubstituted or carry one, two, three or four independently selected substituents R¹², wherein one or two CH₂ groups of the carbo- or heterocycle may be replaced by one or two groups independently selected from the group of C(=0) and C(=S); wherein

R ² is halogen, CN, N0₂, OH, SH, NH₂, Ci-C₆-alkyl, Ci-C₆-haloalkyl,

Ci-C6-alkoxy, Ci-C6-haloalkoxy, Ci-C6-alkylthio, Ci-C6-haloalkylthio, Ci-C4-alkoxy-Ci-C4-alkyl, phenyl or phenoxy; wherein the phenyl moieties of R¹² are unsubstituted or substituted by one, two, three or four independently selected substituents R^12a; wherein

R ^2a is halogen, CN, N0₂, OH, SH, NH₂, Ci-C₆-alkyl, Ci-C₆-haloalkyl, Ci-C6-alkoxy, Ci-C6-haloalkoxy, Ci-C6-alkylthio, C1-C6- haloalkylthio, Cs-Cs-cycloalkyl or Ci-C4-alkoxy-Ci-C4-alkyl; is OR³ or CN; wherein

R³ is hydrogen, Ci-C6-alkyl, C₂-C6-alkenyl, C₂-C6-alkynyl, C₂-C6-alkynyl, Cs-Cs-cycloalkyl, Ci-C6-alkylsulfonyl, phenylsulfonyl, C(=0)-Ci-C4- alkyl, C(=0)-0-Ci-C₄-alkyl, C(=0)-NH(Ci-C₄-alkyl),

alkyl)2, C(=0)-Ci-C4-alkylphenyl, phenyl, phenyl-Ci-C₄-alkyl, phenyl- C2-C₄-alkenyl or phenyl-C2-C₄-alkynyl; wherein the aliphatic, alicyclic and aromatic moieties of R³ are unsubstituted or substituted by one, two, three or four or up to the maximum possible number of independently selected substituents R^3a; wherein

R^3a is halogen, CN , N0₂, OH , C C₄-alkyl, C C₄-halogenalkyl, C₃-C₈-cycloalkyl, Ci-C₄-alkoxy or Ci-C₄-halogenalkoxy; is independently selected from the group consisting of halogen, CN , NO2, OH , SH , d-Ce-alkyl, Ci-C₆-alkoxy, Ci-C₆-alkylthio, Ci-C₆-alkylsulfinyl, Ci-C6-alkylsulfonyl, C2-C6-alkenyl, C2-C6-alkynyl, Cs-Cs-cycloalkyl, C3-C8- cycloalkyloxy, N H₂, NH(Ci-C -alkyl), N(Ci-C₄-alkyl)₂, N H(C₃-C₆-cycloalkyl), N(C₃-C₆-cycloalkyl)₂,

C(=0)-N H(C₃-C₆-cycloalkyl) and C(=0)-N(C₃-C₆-cycloalkyl)₂; wherein the aliphatic and alicyclic moieties of R⁴ are unsubstituted or substituted by one, two, three or four or up to the maximum possible number of independently selected substituents R^4a; wherein

R^4a is halogen, CN , N0₂, OH , C C₄-alkyl, C C₄-haloalkyl, Cs-Cs- cycloalkyl, Ci-C₄-alkoxy or Ci-C₄-halogenalkoxy; is 0, 1 , 2, 3 or 4; is a direct bond or a divalent radical selected from -0-, -S(=0)_p-, -CR^Y1 R^Y2-, -N(R^YN)-, -CR^Y3R^Y4-CR^Y5R^Y6-, -CR^Y7=C^Y8- and -C≡C-, wherein

R^YN, R^Y , R^Y2, R^Y3, R^Y4, R^Y5, R^Y6, R^Y7 and R^Y8 are independently selected from the group consisting of hydrogen, halogen, CN , nitro, OH , Ci-C₄- alkyl, Ci-C₄-halogenalkyl, Ci-C₄-alkoxy and Ci-C₄-halogenalkoxy;

P is 0, 1 or 2; is phenyl or a five- or six-membered heteroaryl, wherein the aromatic moiety is unsubstituted or carries one, two, three or four independently selected radicals R^L; wherein R^L is halogen, CN , N0₂, OH , SH , Ci-C₆-alkyl, Ci-C₆-alkoxy, Ci-C₆- alkylthio, Ci-C6-alkylsulfinyl, Ci-C6-alkylsulfonyl, C2-C6-alkenyl, C2-C6- alkynyl, Cs-Cs-cycloalkyl, C3-Cs-cycloalkyloxy, C3-Cs-cycloalkyl-Ci-C₄- alkyl, N H₂, N H(Ci-C -alkyl), N(Ci-C₄-alkyl)₂, N H(C₃-C₆-cycloalkyl), N(C₃-C₆-cycloalkyl)₂, C(=0)-Ci-C₄-alkyl, C(=0)OH,

alkyl, C(=0)-NH(Ci-C₄-alkyl),

C(=0)-NH(C₃-C₆- cycloalkyl), C(=0)-N(C3-C6-cycloalkyl)2, phenyl and phenyl-Ci-C₄- alkyl; and wherein the aliphatic, alicyclic and aromatic moieties are unsubstituted or substituted by one, two, three or four or up to the maximum possible number of independently selected substituents R^La; wherein

R^La is halogen, CN , N0₂, OH , SH , N H₂, Ci-C₆-alkyl, Ci-C₆-haloalkyl, Ci-C6-alkoxy, Ci-C6-haloalkoxy, Ci-C6-alkylthio, C1-C6- haloalkylthio or Cs-Cs-cycloalkyl; m is 0 or 1 ;

R⁵ and R⁶ are independently selected from the group consisting of hydrogen, halogen, CN , N0₂, OH , SH , Ci-Ce-alkyl, Ci-C₆-alkoxy, d-Ce-alkylthio, C 1 -C6-a I ky I s u If i ny I , Ci-C6-alkylsulfonyl, C2-C6-alkenyl, C2-C6-alkynyl, Cs-Cs- cycloalkyl, Cs-Cs-cycloalkoxy, N H₂, NH(Ci-C -alkyl), N (Ci-C₄-alkyl)₂, N H(C₃-C₆-cycloalkyl), N(C₃-C₆-cycloalkyl)₂,

C(=0)OH ,

or C(=0)-N(Ci-C₄-alkyl)₂, C(=0)-N H(C₃-C₆-cycloalkyl) and C(=0)-N(C₃-C₆-cycloalkyl)₂; wherein the aliphatic and alicyclic moieties of R⁵ and/or R⁶ are unsubstituted or substituted by one, two, three or four or up to the maximum possible number of independently selected substituents R⁵¹ ; wherein

R⁵¹ is halogen, CN , N0₂, OH , SH , N H₂, Ci-Ce-alkyl, Ci-C₆-haloalkyl, Ci-C6-alkoxy, Ci-C6-haloalkoxy, Ci-C6-alkylthio, Ci-C6-haloalkylthio, Cs-Cs-cycloalkyl and Ci-C₄-alkoxy-Ci-C₄-alkyl; or R⁵ and R⁶ together with the carbon atom to which they are bound form a saturated or partially unsaturated three-, four-, five-, six- or seven-membered carbocycle or a saturated or partially unsaturated three-, four-, five-, six- or seven-membered heterocycle, wherein the heterocycle includes beside carbon atoms one, two, three or four heteroatoms independently selected from the group consisting of N , O and S, and wherein the carbo- and heterocycle are

unsubstituted or carry one, two, three or four independently selected substituents R⁵⁶, wherein one or two CH₂ groups of the carbo- or heterocycle may be replaced by one or two groups independently selected from the group of C(=0) and C(=S); wherein is halogen, CN , N0₂, OH , SH , N H₂, Ci-Ce-alkyl, Ci-C₆-haloalkyl, Ci-C6-alkoxy, Ci-C6-haloalkoxy, Ci-C6-alkylthio, Ci-C6-haloalkylthio C 1 -C₄-a I koxy-C 1 -C₄-a I ky I ; or R⁵ and R⁶ together with the carbon atom to which they are bound

(denominated as C^*) form a vinyl group C^*=CR⁵²R⁵³, wherein

R⁵² and R⁵³ are independently selected from the group consisting of hydrogen, halogen, CN, N0₂, OH, SH, NH₂, Ci-C₆-alkyl, Ci-C6-haloalkyl, Ci-C6-alkoxy, Ci-C6-haloalkoxy, Ci-C6-alkylthio, Ci-C6-haloalkylthio and Ci-C4-alkoxy-Ci-C4-alkyl; or R⁵ and R⁶ together with the carbon atom to which they are bound

(denominated as C^*) form a group selected from C^*(=S), C^*(=0) and C^*(=NOR"); wherein

R" is hydrogen, Ci-C6-alkyl, Ci-C6-haloalkyl, C2-C6-alkenyl, C2-C6-alkynyl or Ci-C4-alkoxy-Ci-C4-alkyl;

R⁷ is hydrogen, halogen, CN, Ci-C6-alkyl, Ci-C6-haloalkyl, Ci-C6-alkoxy or Ci-C6-haloalkoxy; and the N-oxides and the agriculturally acceptable salts of the compounds of formula I.

Compounds according to claim 1 , wherein A is N.

Compounds according to claim 1 or 2, wherein R¹ is halogen, CN, NO2, OH, NH2, N(CH₃)₂, d-Ce-alkyl, Ci-C₆-haloalkyl, Ci-C₆-alkoxy, Ci-C₆-haloalkoxy, Ci-C₆- alkylthio, Ci-C6-haloalkylthio, Ci-C4-alkoxy-Ci-C4-alkyl, C2-C6-alkenyl C2-C6- alkynyl or Cs-Cs-cycloalkyl, and wherein R² is hydrogen or a radical as defined for R .

Compounds according to any one of claims 1 or 3, wherein R³ is hydrogen.

Compounds according to any one of claims 1 to 4, wherein n is 1 , 2, 3 or 4 and one radical R⁴ is located in 2-position of the phenyl ring.

Compounds according to any one of claims 1 to 5, wherein R⁴ is independently selected from the group consisting of halogen, CN, NO2, OH, Ci-C6-alkyl, C1-C6- haloalkyl, Ci-C6-alkoxy, Ci-C6-haloalkoxy, C2-C6-alkenyl, C2-C6-alkynyl,

C2-C6-haloalkenyl and C2-C6-haloalkynyl.

Compounds according to any one of claims 1 to 6, wherein R⁵ is hydrogen and R⁶ is d-Ce-alkyl.

8. Compounds according to any of claims 1 to 7, wherein Y is -O- or a direct bond.

9. Compounds according to any of claims 1 to 8, wherein Z is phenyl, wherein the phenyl carries one, two, three or four radicals R^L.

10. Compounds according to any of claims 1 to 9, wherein the group Z-Y- is attached to the phenyl ring in para-position with respect to the triazole bearing residue.

1 1 . A composition comprising an auxiliary and at least one compound of formula I or an N-oxide or an agriculturally acceptable salt thereof according to any of claims

1 to 10.

12. The composition according to claim 1 1 comprising at least one further active substance.

13. A method for combating phytopathogenic fungi, comprising treating the fungi or the materials, plants, the soil or seeds to be protected against fungal attack, with an effective amount of at least one compound of formula I or an N-oxide or an agriculturally acceptable salt thereof, according to any of claims 1 to 10.

14. A use of compounds of formula I, their N-oxides or their agriculturally acceptable salts, according to any of claims 1 to 10 for combating phytopathogenic fungi.

15. Seed treated with a compound of formula I, or an N-oxide or an agriculturally acceptable salt thereof, as defined in any of claims 1 to 10, in an amount of from 0.1 g to 10 kg per 100 kg of seed.